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 JOURNAL READING :

“Safety and ecacy of tinea pedis andonychomycosis treatment in people with

diabetes: a systematic review”

Pembimbing :

dr. Vitalis Pribadi, Sp.KK 

ib!at "leh :#ahmandra $ %S' $ (()*)()**+

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Kepanitraan Klini/ 'lm! Kesehatan K!lit dan Kelamin0a/!ltas Kedo/teran 1niversitas %S'

#!mah Sa/it 2hayang/ata 3/.' #aden Said S!/antoPeriode ( esember *)(4 $ 4 5an!ari *)(4

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 3inea Pedis

Etiologi

• 3.#!br!m• 3.6entagrophytes• 7.0loccos!m

GambaranKlinis

• 2ent!/ 'ntertriginosa•

2ent!/ Vesi/!lar a/!t• 2ent!/ 6occasin 0oot

Diagno

sis

• iagnosis ditega/an berdasar/an gambaran /lini/ dan

pemeri/saan /ero/an /!lit K"8 ()9*)

Terapi

• &nti ;am!r topi/al• &nti ;am!r oral• 3er/adang dengan disertai pengobatan antibioti/

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"n/omi/osis - 3inea 1ng!i!m

Etiologi

•

 3.6entagrophytes• 3.#!br!m

Gambaran Klinik 

•

2ent!/s!b!ng!aldistalis

• 2ent!/ tri/o

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&bstract•

7=ective treatment of tinea pedis and onychomycosis iscr!cial for patients with diabetes as these infections may leadto foot !lcers and secondary bacterial infections res!lting inevent!al lower limb amp!tation

2ac/gro!nd

• & systematic literat!re search of fo!r electronic databases

>Scop!s, 7bsco8ost, "vid, ?eb of Science@ was !nderta/en>-(-((@.

6ethods

• 2ased on the best available evidence identi

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'ntrod!ction

iabetes a=ects approEimately *+Dmillion people worldwide, with

estimates eEpected to rise to 4+million in *)) F(G.

iabetes is associated with an!mber of serio!s and costly healthcomplications, in partic!lar, diabetic

foot !lcers.

2oth tinea pedis and

onychomycosis may lead to thedevelopment of foot !lcers.

'n both cases, in;!ry creates a portal of entryfor pathogens which promotes the

development of f!rther complications

incl!ding cell!litis, osteomyelitis, gangreneand lower limb amp!tation

 3he p!rpose of this st!dy was therefore,to determine the evidence available forthe safety and ecacy of all treatment

interventions

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6ethods

& systematicliterat!re search

was cond!cted todetermine theevidence for all

antif!ngaltreatment

interventions for

ad!lts >aged (+years and older@with tinea pedis

and-oronychomycosis of

the toenails inpeople with

diabetes.

Criteria forincl!sion

 3he primary o!tcomemeas!res assessed in

this review wereHsafetyI and HecacyI.

HSafetyI was deB6 and K3@independently applied these

criteria to locate trials forthis review.

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• 0o!r electronic databases >Scop!s, 7bsco8ost,"vid, ?eb of Science@ were searched !sing thesearch strategy s!mmarised in 3able (.

Systematic search

strategy

• &ll st!dies incl!ded in this review were readby two reviewers independently >B6 and K3@for content eEtraction and appraised for theirlevel of evidence !sing the J86#C hierarchyof evidence scale FG >3able *@.

7val!ation, analysis andsynthesis of st!diesincl!ded for review

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#es!lt

 3he systematic reviewidenti

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