Allergy & Immunology (Titles published by Nova Science)

Gazelle AcademicAllergy & Clinical Immunology

Titles published by Nova Science

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Bacteriology ResearchDevelopments

Cell Biology Research

Eye & VisionResearch

Developments

Health & HumanDevelopment

Human Anatomy &Physiology

Immunology &Immune System

Disorders

Protein Biochemistry,Synthesis,

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CONTENTS

ALLERGIES & INFECTIOUS DISEASES 1

BACTERIOLOGY RESEARCH DEVELOPMENTS 3

CELL BIOLOGY RESEARCH 4

EYE & VISION RESEARCH DEVELOPMENTS 4

HEALTH & HUMAN DEVELOPMENT 5

HUMAN ANATOMY & PHYSIOLOGY 5

IMMUNOLOGY & IMMUNE SYSTEM DISORDERS 5

PROTEIN BIOCHEMISTRY, SYNTHESIS, STRUCTURE & CELLULAR FUNCTIONS 12

ALLERGIES & INFECTIOUS DISEASES

ALLERGIES & AUTISMMichael J. Dochniak, Denise H. Dunn

The immune-response perspective in cognitive development is intended to explore how certainenvironmental proteins and genetic factors affect neuro-cognitive development and mentalhealth thereafter. Specifically, naturally occurring proteins are known to cause severe andpervasive immune responses. More specifically, environmental antigenic/allergenic proteinsmay trigger IgE mediated reaction antibodies that influence cross-react immune responses tohomologous exogenous/endogenous proteins. Repeated exposure to antigenic/allergenicproteins has been shown to cause an increased incidence of sensitisation, adverse allergicreactions, and even death through anaphylactic shock.

PB 9781608763528 £35.99 May 2010 Nova Science 132 pages

NEW TITLEANAPHYLAXISPrinciples & PracticeEdited by M. Thirumala Krishna

This is a clinical text for practising Allergists and Clinical Immunologists providing an evidence-based systematic problem oriented approach in investigation and management of this lifethreatening condition. This book has received excellent contributions from internationalexperts from various countries and each chapter has embraced recent advances as well asinternational recommendations giving the reader 'best practice' parameters. Special features ofthis book include 'clinical cases' to compliment the text and put the reader into a clinicalperspective and 'clinical pearls' at the end of each chapter with 'key take home messages'. Wehope that this text will be helpful to the specialist physician in the provision of good quality ofcare for their patients.

HB 9781626186880 £124.99 July 2013 Nova Science 319 pages


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BACTERIAL INFECTIONSCharacteristics, Types & TreatmentEdited by Jonas Müller, Luka Koch

In this book, the authors present topical research in the study of the characteristics, types andtreatment of bacterial infections. Topics discussed include chronic pseudomonas aeruginosainfection in cystic fibrosis; bacteriophage therapy; antimicrobial applications of phages; humancutaneous tuberculosis and skin dendritic cells; the pathophysiology and prevention ofbacterial endocarditis and current antibiotics for ocular infections.

HB 9781619423657 £79.50 June 2012 Nova Science

CYTOMEGALOVIRUS INFECTIONSRisk Factors, Causes & ManagementIrmeli Lautenschlager

This book deals primarily with pathogenesis, specific immunology, clinical management andefforts to prevent and treat Cytomegalovirus infection. The book includes chapters on themanagement of CMV infection in pregnancy, CMV and male fertility, CMV and immunity, riskfactors, diagnosis and impact on immunity and health, as well as antiviral and vaccine strategiesagainst CMV.

HB 9781619422216 £154.50 April 2012 Nova Science 338 pages

HOW TO PREVENT & SURVIVE FOOD-BORNE DISEASESAlcides Troncoso

Given that micro-organisms are everywhere, they naturally appear in plants and animals. Asmall percentage of these micro-organisms are pathogenic and, therefore, require controlmeasures. It could be thought that finding a microbial etiological agent in a food could be veryuseful. But, maybe, the detection in foods of micro-organisms will only be tackled when anoutbreak occurs. This book focuses on how to prevent and survive food-borne diseases.

PB 9781619426832 £43.50 July 2012 Nova Science 62 pages

LEISHMANIASISSymptoms, Treatment & Potential ComplicationsEdited by Carlos Sepulveda

The leishmaniases are vector-borne diseases due to infection caused by parasitic protozoansbelonging to the Leishmania genus, which find hosts in various wild and domestic animals andcan be occasionally transmitted to humans by insect vectors. In this book, the authors discussthe symptoms, treatment and potential complications of leishmaniasis. Topics includeimmunity against leishmaniasis; the clinical haematology, epidemiology and aetiology ofleishmaniasis; the role of neutrophils in visceral leishmaniasis; atypical manifestations of caninevisceral leishmaniasis; and the parasitological and serological diagnosis of canine visceralleishmaniasis.

PB 9781624177002 £57.50 April 2013 Nova Science 91 pages


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PEANUTSBioactivities & AllergiesEdited by Iván López Expósito, Ana Belen Blazquez

The peanut is an important crop grown on over 21 million hectares worldwide. Althoughpeanuts have had an adverse image due to their content in saturated fatty acids, it is importantto mention they also are an excellent source of protein, vitamins, and minerals for humannutrition. In addition, peanuts contain relevant bioactive constituents that can provide a widerange of health benefits. Unfortunately, peanuts are also one, if not, the most allergenicvegetables and the most common food-related cause of IgE-mediated allergic reactions, mainlyin westernised countries. This book will present an up-to-date overview regarding peanutcomposition, physical characteristics and bioactive properties. The second part will coverpeanut and legume allergen characteristics, together with their prevalence. In addition, thetherapeutic strategies to treat peanut allergy and the problem regarding the cross-reactivity ofpeanut and other allergens will be discussed.

HB 9781624173875 £91.99 April 2013 Nova Science 138 pages

PLASMODIUM FALCIPARUMMorphology, Life Cycle & Health ImpactEdited by Ghislaine Mayer

Malaria is one of the most prevalent infectious diseases worldwide. Severe malaria leads to thedeath of close to two million individuals every year. Plasmodium falciparum, the causativeagent of the most severe form of malaria is becoming increasingly resistant to current drugs,including artemisinin. This book presents current advances and comprehensive material in thebiology of the parasite responsible for the most enduring and devastating disease of mankind.This book addresses P. falciparum infection and severe malaria, the role of heat shock proteinsin the development and pathogenicity of the parasite, the biosynthesis of isoprenoid,specifically the methylerythritol phosphate (MEP) pathway in the erythrocytic stages of theparasite is described.

HB 9781622573608 £124.99 January 2013 Nova Science 148 pages

BACTERIOLOGY RESEARCH DEVELOPMENTS

GERMS & TISSUESFrank Macfarlane Burnet, Peter Brian Medawar & the ImmunologicalConjunctureHyung Wook Park

The Nobel Prize in Physiology and Medicine in 1960 was awarded to two renowned scientists inAustralia and Britain, Frank Macfarlane Burnet and Peter Brian Medawar. Many historicalaccounts have described Burnet's theoretical prediction of immunological "tolerance" and itsexperimental confirmation by Medawar as a momentous achievement in immunology. Thisbook examines their distinct research pathways, especially their different ways of approachingthe immunological changes of the host organism during embryogenesis and foetaldevelopment.

PB 9781616684112 £35.99 September 2010 Nova Science


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CELL BIOLOGY RESEARCH

HANDBOOK OF MACROPHAGESLife Cycle, Functions & DiseasesEdited by Rikiya Takahashi, Hibiki Kai

Macrophages are widely distributed innate immune cells, which play a pivotal role not only inthe primary response to pathogens but also in adaptive immune response, in tissue repair andin the maintenance of local tissue homoeostasis. This book includes current research in the lifecycle, functions and diseases associated with macrophages. Topics discussed includemacrophages as regulatory and effector cells in the immune system; macrophages from humanpluripotent stem cells; mucosal macrophage phenotype and functionality in homoeostasis andpathology; macrophage plasticity and polarization; defective macrophage function in Crohn'sdisease; macrophages in viral infection and atherosclerosis; and macrophage polarization in thecourse and treatment of autoimmune diseases.


EYE & VISION RESEARCH DEVELOPMENTS

NEW TITLEALLERGIC DISORDERS OF THE OCULAR SURFACEDe Gaulle I. Chigbu

This is a textbook for students and practitioners involved in the management of patients withocular allergy. Allergic disorders of the ocular surface affect more than 20% of the generalpopulation and they are ocular diseases in which IgE- and/or T-lymphocyte mediatedmechanisms are involved. They can have a significant impact on an individual's quality of life.This book addresses the important aspects of allergic disorders of the ocular surface withparticular emphasis on the pathomechanism and pharmacotherapy of the different types ofocular allergy. The cellular and molecular mechanisms involved in the pathomechanism ofallergic eye diseases, as well as the lymphocytic activation process are also discussed. The bookwill provide the reader with considerable insight into the pharmacotherapy of allergic eyediseases with emphasis on the clinical pharmacology of anti-allergic and anti-inflammatorypharmaceutical agents.

HB 9781624176142 £70.99 June 2013 Nova Science 126 pages


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HEALTH & HUMAN DEVELOPMENT

HUMAN IMMUNODEFICIENCY VIRUS (HIV) RESEARCHSocial Science AspectsHugh Klein, Joav Merrick

Looking back over the course of the three-plus decades of the HIV/AIDS epidemic, scholars andresearchers have made many significant strides in understanding and responding to HIV andAIDS. From the inception of the HIV/AIDS epidemic during the early 1980s until the mid-1990s,when highly active antiretroviral treatment (HAART) was introduced as an innovative andhighly-effective way of controlling HIV and HIV-related diseases, the "average" persondiagnosed as being HIV-positive could expect to live for several months and if lucky, for a fewyears. Today, with the medical advances that have been made in the fight against HIV/AIDS,people who have contracted HIV usually can expect to live relatively healthy lives, in mostinstances for many years without experiencing any serious complications of HIV disease. Thisbook focuses on the social science aspects of current HIV research.

HB 9781620812938 £124.99 October 2012 Nova Science 133 pages

HUMAN ANATOMY & PHYSIOLOGY

SARCOIDOSISDiagnosis, Epidemiology & Treatment OptionsEdited by Michael R. Connor, Ryan S. Stevens

Sarcoidosis is a systemic inflammatory granulomatous disease of unknown origin, with a widevariety of imaging features. The organs most commonly involved are the lungs, eyes, and skin.The characteristic histologic lesion, a non-caseating granuloma, has been described as affectingall organ systems. In this book, the authors present topical research in the study of thediagnosis, epidemiology and treatment options for sarcoidosis. Topics include recent advancesin the immunogenetics of sarcoidosis; nodular sarcoidosis; pulmonary hypertension associatedwith sarcoidosis; nuclear medicine imaging in the diagnosis of cardiac sarcoidosis and anexperimental model of sarcoidosis using Kveim tissue.

HB 9781621007647 £79.50 December 2011 Nova Science 166 pages

IMMUNOLOGY & IMMUNE SYSTEM DISORDERS

ANTIBIOTIC RESISTANCEEdited by Rufus Finley, Marcos Solomon

Infections that were once treatable have become more difficult to treat because of antibioticresistance. Antibiotics have saved millions of lives, but antibiotic use in food animalscontributes to the emergence of resistant bacteria that may affect humans. The Departmentsof Health and Human Services (HHS) and Agriculture (USDA) are primarily responsible forensuring food safety. This book presents the risk assessment and monitoring efforts ofantibiotic resistance.



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ANTIMICROBIAL PEPTIDESProperties, Functions & Role in Immune ResponseEdited by Myung-Dae Seong, Young-Il Hak

Antimicrobial peptides (AMPs) are small peptides which exhibit broad-spectrum antimicrobialactivity and often activity against virus. In addition, AMPs exert several functions includingendotoxin neutralization, chemotactic and immunomodulating activities, angiogenesis, andwound repair. In this book, the authors discuss the innate immune system andlipopolysaccharides; the biological role of fish antimicrobial peptides; casein-derived peptides;antimicrobial peptides in intestinal inflammation and infection; insect antimicrobial peptides inimmunity and mechanisms of action; potential of AMPs as therapeutic tools against infectiousdisease; and how LC-MS/MS-based quantitative protein profiling can aid mechanistic studies ofantimicrobial peptides.

HB 9781622578436 £124.99 March 2013 Nova Science 168 pages

ARTHRITISTypes, Treatment & PreventionEdited by Marc N. Pelt

Osteoarthritis (OA) also known as degenerative arthritis or degenerative joint disease, is agroup of mechanical abnormalities involving degradation of joints, including articular cartilageand subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, andsometimes an effusion. Psoriatic arthritis is a type of inflammatory arthritis that will develop inup to 30 percent of people who have the chronic skin condition psoriasis. This book presentstopical research on both these topics including the pharmacological treatment of osteoarthritis;the health effects and current treatment of psoriasis and psoriatic arthritis; the role ofaquaporins in human synovitis and subclinical atherosclerosis in patients with psoriatic arthritis.

HB 9781614707196 £79.50 April 2012 Nova Science

AUTOANTIBODIESDetection, Pathogenicity & Health ImplicationsEdited by Graham E. Jenkins, Joanne I. Hall

Autoantibodies that are directed against self-antigens are called autoantibodies. Not allautoantibodies are harmful. Autoantibodies can be useful in the removal of cell debris duringinflammation. Some autoantibodies may be the actual pathogenic agents of autoimmunedisease, the secondary consequences of tissue damage, or the harmless footprints of anetiologic agent. In this book, the authors present current research in the detection,pathogenicity and health implications of autoantibodies. Topics include the implicatedautoantibodies in kidney disease and Alzheimer's disease; autoimmunity in cardiovasculardisease; detection and analysis of natural autoantibodies; and B Cells and autoantibodies inmultiple sclerosis.

HB 9781620815601 £99.99 September 2012 Nova Science


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CHRONIC FATIGUE SYNDROMESymptoms, Causes & PreventionEdited by Edita Svoboda, Kristof Zelenjcik

Chronic fatigue syndrome (CFS) is a complicated disorder characterised by extreme fatigue thatdoesn't improve with bed rest and may worsen with physical or mental activity. Chronic fatiguesyndrome may occur after an infection, such as a cold or viral illness. The onset can also beduring or shortly after a time of great stress, or it may come on gradually without a clearstarting point or obvious cause. This book discusses new research in CFS, including the effectsthat CFS may have on immune system responses. The possible implications and prevention ofCFS are also explored.

HB 9781607414933 £120.99 August 2010 Nova Science 189 pages

NEW TITLECHRONIC INFLAMMATIONCauses, Treatment Options & Role in DiseaseEdited by Wei-Chiao Chang, Wen-Chang Chang

The primary focus of this book is to provide readers with a comprehensive overview of therecent advances in inflammation, especially in molecular biological and clinical aspects.Chapters contained in this book are written by invited authors from all over the world, who arewell-known experts in their respective fields. In the book, chapters discussed include themolecular basis of inflammatory mechanisms, the functional roles of inflammation in diseasesand new treatments of anti-inflammation. This book will be useful to all who wish tounderstand the scientific basis of inflammatory disease.


DNA VACCINESTypes, Advantages & LimitationsEdited by Erin C. Donnelly, Arthur M. Dixon

DNA vaccination is one of the most promising techniques for immunisation against diseasescaused by viruses, protozoa, bacteria, and even for tumours and illnesses with genetic origins.These vaccines can be administered by direct inoculation of plasmid by several routes. In thisbook, the authors present topical research in the study of the types, advantages and limitationsof DNA vaccines. Topics discussed include the role of novel carrier constructs in effective andsafe DNA vaccine delivery; improving the immunogenicity of DNA vaccines; the role of DNA-IL-12 vaccination in cosinphilic inflammation; genetic immunisation enabling re-direction of thehost immune system resulting in the development of effective immune responses; and DNAvaccination against herpesvirus.



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ENCYCLOPEDIA OF IMMUNOLOGY RESEARCH3 Volume SetEdited by Meredith E. Daniels

This book presents current research in the study of immunology. Topics discussed include TLRagonists as immune adjuvants; modulating immune response with CpG-Oligodeoxynucleotidethrough the skin; evolution of immunosuppression in liver transplantation; the role ofpharmacogenomics in tailoring immunosuppressive therapy for liver transplant recipients;sunlight induced immunosuppression; antibiotic resistance and probiotics; antibiotic resistancein food lactic acid bacteria and nanobiotics to combat bacterial drug resistance.

HB 9781613248591 £329.50 January 2011 Nova Science

IMMUNITY & IMMUNOTHERAPY OF HUMAN FUNGAL INFECTIONSMawieh Hamad, Khaled Abu-Elteen

Immunity and immunotherapy of human fungal infections is an up-to-date in-depth assessmentof the current status of immune-based anti-fungal preventive and therapeutic interventions.This book consists of integrative chapters that deal with the subject from different angles. Alsodiscussed herein is an updated review of medically important fungi, the diseases they cause,morbidity and mortality trends that associate with them, conventional anti-fungalchemotherapy, and non-immune-based (actual and/or potential) unconventional treatments.The intended audiences of this book include, but are not limited to, students, researchers, andpractitioners in the general fields of immunology, mycology, dermatology, and allergy.

HB 9781617289767 £74.50 June 2011 Nova Science

IMMUNOTHERAPYActivation, Suppression & TreatmentsEdited by Blake C. Facinelli

Immunotherapy is a medical term defined as "treatment of disease by inducing, enhancing, orsuppressing an immune response". Immunotherapies are designed to elicit or amplify animmune response and are classified as activation immunotherapies. Immunotherapiesdesigned to reduce, suppress or more appropriately direct an existing immune response, as incases of autoimmunity or allergy, are classified as suppression immunotherapies. This bookpresents topical data on immunotherapies including: antifungal immunotherapy; active andspecific immunotherapeutical strategies for the prevention and treatment of cancer; allergenimmunotherapy; dendritic cell/tumour fusion cell vaccine in cancer therapy; CRLA-4 inhibitionin malignant melanoma; and others.

HB 9781616685850 £107.50 March 2011 Nova Science 241 pages

INFLIXIMABPharmacology, Uses & LimitationsEdited by Antonio D. Medrano Acevedo, Montserrat Fajardo Gaitan

Infliximab is an established therapy for some auto-immune diseases like rheumatoid arthritis,Crohn's disease, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis and ulcerative colitis.In this book, the authors present current research in the study of the pharmacology, uses andlimitations of infliximab. Topics discussed include the risk of infection in patients treated withinfliximab; the efficacy and safety of infliximab during pregnancy and breastfeeding in womenwith inflammatory bowel disease; and disease activity, treatment response and drugcontinuation rates among patients with rheumatoid arthritis treated with infliximab.

HB 9781619423435 £79.50 August 2012 Nova Science 188 pages


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LUPUSSymptoms, Treatment & Potential ComplicationsEdited by Thiago Devesa Marquez, Davi Urgeiro Neto

Lupus is one of many disorders of the immune system known as auto-immune diseases,wherein the immune system attacks parts of the patient's body, leading to inflammation andinjury in body tissues. This book presents current research in the study of the symptoms,treatment and potential complications of lupus. Topics include autoantibody-producing B cellsand B cell therapy in systemic lupus erythematosus; neuropsychiatric and hematologicmanifestations of systemic lupus erythematosus; pulmonary hypertension in systemic lupuserythematosus; dual roles for antibodies in lupus nephritis; and treatment of systemic lupuserythematosus with intravenous immunoglobulins.

HB 9781620810781 £116.99 August 2012 Nova Science

MOLECULAR ASPECTS OF INFECTIOUS DISEASESEdited by Mazen T. Saleh

This book contains material relevant for students and researchers interested in the basicscience of infectious diseases. The material in this book is organised into three major sections.The first describes the structures of various pathogenic microbes. The emphasis in this sectionis on the surface structures as they mediate the critical step of adsorption of pathogens to theirtarget host cells. There is also a subsection on protein secretion in bacteria. The second sectionreviews the basics of innate immunity as these are the first line of immune defence and areimportant to understand the immunological response and its consequences on the healthstatus and physiological balance in the host. The third section provides a description of anumber of infectious diseases, particularly those of the respiratory system and prion-relatedinfections.

HB 9781617286902 £129.50 February 2011 Nova Science 206 pages

NEW TARGETS & APPROACHES TO AUTOIMMUNE-INDUCED SALIVARYHYPOFUNCTIONDouglas Dickinson, Kalu Ogbureke, Scott De Rossi, Stephen Hsu

The pathogenesis of autoimmune diseases is multifaceted, and the complexity of symptoms,diagnosis and treatment options associated with these diseases reflects this. Sjogren'ssyndrome (SS) is an autoimmune disorder affecting up to 4 million Americans, and results fromautoimmune reactions in secretory glands (primary SS) and other tissues (secondary SS).Current treatment options for SS are aimed largely at amelioration of symptoms, but withoutfunctional restoration in the secretory glands. Prescribed medications for salivary hypo-function or xerostomia are often associated with severe side effects, typically due to the effectsof systemically administered muscarinic cholinergic receptor agonistis. This book presentsresearch on novel agents for treatment of autoimmune disorders.

PB 9781611223071 £35.99 February 2011 Nova Science 49 pages


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QUANTITATIVE IMMUNOHISTOLOGYProblems & SolutionsAnthony S-Y Leong, Trishe Y-M Leong

As immunohistochemistry enters its fourth decade as a diagnostic tool, this analyticalprocedure continues to experience poor reproducibility, albeit in specific situations. Theproblem becomes more important with the mounting pressure to employ the assay in aquantitative manner for the assessment of therapeutic and prognostic markers in a number ofneoplasms. Qualitative applications of immunohistochemistry are well established andcontinue to increase with the range of sensitive antibodies and detection systems available,however, numerous variables that influence the immunoexpression of proteins in formalin-fixed tissue continue to exist in the pre-analytical and analytical phases of the test procedure.This book emphasises these problems in detail and suggests possible solutions.

PB 9781616682613 £35.99 August 2010 Nova Science 70 pages

RHEUMATOID ARTHRITISPrevalence, Risk Factors & Health EffectsEdited by Michael H. Madsen

Rheumatoid arthritis (RA) is a chronic inflammatory auto-immune disease characterised byprogressive joint destruction resulting from chronic synovial inflammation. It leads to variousdegrees of disability, and ultimately has a profound impact on the social, economic,psychological, and sexual aspects of the patient's life. This book presents current research fromacross the globe in the study of rheumatoid arthritis, including the relevance of genetic riskfactors in rheumatoid arthritis; cervical reconstruction for cervical disorders in rheumatoidarthritis; sub-clinical atherosclerosis in patients with rheumatoid and psoriatic arthritis; andhand involvement and quality of life effects on patients with rheumatoid arthritis.


NEW TITLESCLERODERMASymptoms, Diagnosis & TreatmentEdited by Romain De Winter

Systemic sclerosis or scleroderma is an autoimmune disease characterised by widespreadmicroangiopathy, immune system alterations and fibrosis of the skin and internal organs. Thisbook presents current research in the study of the symptoms, diagnosis and treatment ofscleroderma. Topics discussed include the identification and treatment of the pulmonarymanifestations of systemic sclerosis; interstitial lung disease in systemic sclerosis; nailfoldcapillaroscopy and early diagnosis of systemic sclerosis; localised scleroderma; evaluation of anew CENPB epitope array for systemic sclerosis-associated centromere autoantibodies; andiloprost in the treatment of Raynaud phenomenon secondary to scleroderma.

PB 9781626188020 £57.50 July 2013 Nova Science 101 pages


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NEW TITLESYSTEMIC LUPUS ERYTHEMATOSUS (SLE)Prevalence, Pathophysiology & PrognosisEdited by Syuichi Koarada

Systemic lupus erythematosus (SLE) is one of the prototypical systemic autoimmune diseasescharacterised by inflammation, immune complex deposition, and vasculitis. Patients with SLEshow various symptoms and clinical images, both constitutional and specific organ symptoms.They include the skin, joints, muscles, kidneys, lungs, nervous system, and blood vessels.Although the aetiology of the disease is still unclear, genetic, hormonal, immunologicabnormalities and environmental factors complicatedly play important roles in thepathophysiology in SLE. It is evident that multiple genes show genetic susceptibility to SLE.Environmental factors of SLE and immunologic abnormalities, especially the production of anumber of auto-antibody, are important features of the disease. In this book, we presentrecent knowledge about the prevalence, pathophysiology and prognosis of SLE. The bookincludes various interesting chapters: Chapter One: An illustrated overview of the prevalenceand clinical symptoms of systemic lupus erythematosus; Chapter Two: Pathophysiology ofsystemic lupus erythematosus; Chapter Three: MBL and MBL genotypes in SLE; Chapter Four:Novel biological activities of autoantibodies as the potential markers of systematic lupuserythematosus; Chapter Five: Cytokines in systemic lupus erythematosus (sle) with clinicalaspects and prognostics; Chapter Six: Prognosis in systemic lupus erythematosus; ChapterSeven: Auto-antibody-producing RP105-negative B cells in humans and a murine model of lupuserythematosus.


TECHNIQUES IN EPIDERMAL BIOLOGYAn Integrated Approach to Autoimmune Skin DiseaseEdited by Nicola Cirillo

The high-throughput techniques underlying a systems level analysis of biological organismshave emerged as powerful tools in the study of disease mechanisms. On the other hand, theyrequire substantial funding and multidisciplinary skills. Therefore, basic biochemical/cellbiology methods from molecular bioscience are still needed to address key biological questions.This book uses the auto-immune disease Pemphigus Vulgaris (PV) as an experimental model ofepidermal disease. Simple molecular bioscience principles and high-throughput methods toclarify disease pathophysiology are presented, which lead to novel therapeutic modalities.


NEW TITLETYPE I INTERFERON IN AUTOIMMUNE DISEASES & ITS CLINICAL APPLICATIONSEdited by Yihong Yao

Type I interferons (IFNs), especially IFN-& 945;/& 946;, have multiple biological functionsincluding anti-viral and anti-bacterial properties, immuno-modulation, anti-proliferation, andintensive studies over decades have also revealed important roles in auto-immunity andcancer. Sustained Type I IFN elevation has been implicated in immune responses against self-antigens and tissue damage, which has led to the hypothesis that type I IFN might play a criticalrole in the pathogenesis of some auto-immune and inflammatory diseases. This book providesan overview of many key topics surrounding type I IFNs, beginning with detailed discussion ofthe type I IFN signalling pathway, the interplay between components that regulate thispathway, its involvement in auto-immunity, and a detailed review of the roles of type I IFNs in aseries of well characterised inflammatory and auto-immune diseases.



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VACCINATIONSProcedures, Types & ControversyAdeline I. Bezio, Braydon E. Campbell

Vaccines play an essential role in keeping humans and animals healthy. The vaccine has beenone of the most important interventions designed to both prevent and to treat diseases,strengthening and improving the weakened immune system. In this book, the authors discussveterinary sector vaccines and how they may be applied to improve human vaccines;immunisation recommendations for healthcare workers; a new vaccination method forexogenous and endogenous antigen initiated disorders; the impact of vaccination on diseaseprevention and control; and T-Cell vaccination for multiple sclerosis.


PROTEIN BIOCHEMISTRY, SYNTHESIS, STRUCTURE & CELLULAR FUNCTIONS

INTERFERONSCharacterization, Mechanism of Action & Clinical ApplicationsEdited by Joe H. Thomas, Adrian Roberts

Interferons are cytokines that are very important in regulating both innate and adaptiveimmune response. Of the two different types of interferons, Type I interferons are potentmediators of the innate immune response against viruses and cancer. Type II interferons,mainly IFN-y enhances T cell polarisation in the lymph nodes that result in their expansion. Thisbook discusses the characterisation, mechanisms of action and clinical applications ofinterferons. Topics include interferon-gamma, oligodendrocyte injury and inflammatorydemyelination; the role of IFN-y in oesophageal squamous cell carcinoma; interferons inmultiple sclerosis; the effect of interferons on NK cell activity in HIV infection and tumour celldevelopment; and understanding the mechanisms of interaction between serine proteases,serine protease receptors and interferons.

HB 9781620812983 £124.99 October 2012 Nova Science 172 pages


Gazelle AcademicAllergy & Clinical Immunology – Titles published by Nova Science

Pricelist (April 2014)

ALLERGIC DISORDERS OF THE OCULAR SURFACE 2013 HB 9781624176142 £70.99

ALLERGIES & AUTISM 2010 PB 9781608763528 £35.99

ANAPHYLAXIS 2013 HB 9781626186880 £124.99

ANTIBIOTIC RESISTANCE 2012 HB 9781619424166 £104.50

ANTIMICROBIAL PEPTIDES 2013 HB 9781622578436 £124.99

ARTHRITIS 2012 HB 9781614707196 £79.50

AUTOANTIBODIES 2012 HB 9781620815601 £99.99

BACTERIAL INFECTIONS 2012 HB 9781619423657 £79.50

CHRONIC FATIGUE SYNDROME 2010 HB 9781607414933 £120.99

CHRONIC INFLAMMATION 2013 HB 9781628080940 £124.99

CYTOMEGALOVIRUS INFECTIONS 2012 HB 9781619422216 £154.50

DNA VACCINES 2012 HB 9781613244449 £116.99

ENCYCLOPEDIA OF IMMUNOLOGY RESEARCH 2011 HB 9781613248591 £329.50

GERMS & TISSUES 2010 PB 9781616684112 £35.99

HANDBOOK OF MACROPHAGES 2012 HB 9781620811627 £191.99

HOW TO PREVENT & SURVIVE FOOD-BORNE DISEASES 2012 PB 9781619426832 £43.50

HUMAN IMMUNODEFICIENCY VIRUS (HIV) RESEARCH 2012 HB 9781620812938 £124.99

IMMUNITY & IMMUNOTHERAPY OF HUMAN FUNGAL INFECTIONS 2011 HB 9781617289767 £74.50

IMMUNOTHERAPY 2011 HB 9781616685850 £107.50

INFLIXIMAB 2012 HB 9781619423435 £79.50

INTERFERONS 2012 HB 9781620812983 £124.99

LEISHMANIASIS 2013 PB 9781624177002 £57.50

LUPUS 2012 HB 9781620810781 £116.99

MOLECULAR ASPECTS OF INFECTIOUS DISEASES 2011 HB 9781617286902 £129.50

NEW TARGETS & APPROACHES TO AUTOIMMUNE-INDUCED SALIVARY HYPOFUNCTION 2011 PB 9781611223071 £35.99

PEANUTS 2013 HB 9781624173875 £91.99

PLASMODIUM FALCIPARUM 2013 HB 9781622573608 £124.99

QUANTITATIVE IMMUNOHISTOLOGY 2010 PB 9781616682613 £35.99

RHEUMATOID ARTHRITIS 2011 HB 9781617619311 £98.50

SARCOIDOSIS 2011 HB 9781621007647 £79.50

SCLERODERMA 2013 PB 9781626188020 £57.50

SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) 2014 HB 9781628089905 £70.99

TECHNIQUES IN EPIDERMAL BIOLOGY 2012 HB 9781612096216 £40.99

TYPE I INTERFERON IN AUTOIMMUNE DISEASES & ITS CLINICAL APPLICATIONS 2013 HB 9781624173790 £145.99

VACCINATIONS 2012 HB 9781620810361 £124.99

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Gazelle AcademicAllergy & Clinical Immunology

Titles published by Nova Science

Allergies &/ŶĨĞĐƟŽƵƐ��ŝƐĞĂƐĞƐ�

Bacteriology ResearchDevelopments

Cell Biology Research

Eye & VisionResearch

Developments

Health & HumanDevelopment

Human Anatomy &Physiology

Immunology &Immune System

Disorders

Protein Biochemistry,Synthesis,

Structure &�ĞůůƵůĂƌ�&ƵŶĐƟŽŶƐ�

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Allergy & Immunology (Titles published by Nova Science)

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