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100
International Union of Nutritional Sciences (IUNS)
Federation of European Nutrition Societies (FENS)
IUNS
An Official Journal of
S. KargerMedical and Scientifi c PublishersBasel . Freiburg . Paris . London . New York . New Delhi . Bangkok . Beijing . Tokyo . Kuala Lumpur . Singapore . Sydney
Ann Nutr Metab61(3) 181–270 (2012) 61 | 3 | 12 print
ISSN 0250–6807onlinee-ISSN 1421–9697
www.karger.com/anm
ISBN 978–3–318–02288–9
The Discovery of Vitamins100th Anniversary Special Issue
EditorsR.D. Semba, Baltimore, Md.K. Kraemer, Basel
An up-to-date and comprehensive handbook
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Vitamin A plays a key role among the vitamins es-sential for healthy growth and development. Vitamin A defi ciency disorders (VADD) are therefore an im-portant part of general malnutrition that in the ma-jority of cases leads to failure to thrive and under-weight. Moreover, apart from adverse eff ects on health and survival in general, VADD can also lead to blindness, called xerophthalmia, and are also fre-quently accompanied by various infections. Last but not least, it has become evident that even mild de-grees of VAD (and all other forms of nutritional defi -ciencies) have important adverse implications for health and are thus much more widespread than previously assumed.This publication systematically covers detailed and up-to-date information on every relevant aspect of VADD, with particular emphasis on providing an out-line of their setting, nature, and signifi cance. In addi-tion to cutting-edge scientifi c information, the latest available data on the global occurrence of VAD from the World Health Organization is also included.
Contents
AcknowledgementsPrefaceForeword
• Foreground• Vitamin A in Nature• Methods of Analysis• Food Sources• Bioavailability of Carotenoids• Vitamin A in Health• Assessment of Vitamin A Status• Xerophthalmia• Mortality and Morbidity Especially in
Relation to Infections• Other Eff ects of VAD• Interaction of Vitamin A and
Other Micronutrients• Global Occurrence• Epidemiology• Retinoids and Carotenoids in
General Medicine• Control
Manual on Vitamin A Defi ciency Disorders (VADD)EditorsDonald S. McLarenKlaus Kraemer
World Review of Nutrition and Dietetics
Editor: B. Koletzko
Vol. 103
Manual on Vitamin A Deficiency Disorders (VADD)Editors
D.S. McLarenK. Kraemer
cLarenmer
ADD
Karger – Medical and Scientifi c PublishersCH–4009 Basel, Switzerlandorders@karger.ch, f: +41 61 306 12 34www.karger.com
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Manual on Vitamin A Defi ciency Disorders (VADD)Editors: McLaren, D.S. (Worthing); Kraemer, K. (Basel)XII + 192 p., 76 fi g., 4 in color, 55 tab., hard cover, 2012CHF 196.– / EUR 163.– / USD 231.00Prices subject to changeEUR price for Germany, USD price for USA onlyISBN 978–3–318–02143–1e-ISBN 978–3–318–02144–8
World Review of Nutrition and Dietetics, Vol. 103Series Editor: Koletzko, B. (Munich)Listed in MEDLINE/PubMed
KI12649
Printed in Switzerland on acid-free and non-aging paper (ISO 9706) by Reinhardt Druck, Basel
Appears every 6 weeks: 2 volumes per year (8 issues)
Editor
B. Koletzko, Munich
Assistant Editor
B. Kessler, Munich
Associate Editors
P.S.W. Davies, Brisbane, Qld.L. de Groot, WageningenG. Desoye, GrazA. Gil, GranadaJ. Heinrich, NeuherbergR. Meier, LiestalS. Nagata, IzunokuniL. Poston, LondonM. Schulze, NuthetalM.B. Zimmermann, Zurich
Editorial Board
A. Astrup, CopenhagenA. Berg, FreiburgZ.A. Bhutta, KarachiS.C. Bischoff, StuttgartF. Branca, RomeR. Brigelius-Flohé, NuthetalP.C. Calder, SouthamptonS. Carlson, Kansas City, Kan.I. Cetin, MilanR.J. Deckelbaum, New York, N.Y.T. Decsi, Pécs
C.J. Field, EdmontonK. Godfrey, SouthamptonR. Hakkak, Little Rock, Ark.W.S. Harris, Sioux Falls, S. Dak.H. Hauner, MunichM. Hernández-Triana, HavanaH. Heseker, PaderbornE. Hypponen, LondonJ. Kopecky, PragueM. Krawinkel, GiessenM. Lamprecht, GrazW. Langhans, ZurichJ. Linseisen, HeidelbergO. Ljungqvist, ÖrebroJ.A. Martinez, PamplonaH.J. McArdle, AberdeenY. Naito, KyotoP.W. Nathanielsz, San Antonio, Tex.H. Oberritter, BonnR. Saffery, Parkville, Vic.W.H.M. Saris, MaastrichtL. Serra-Majem, Las Palmas de Gran
CanariaC. Sieber, NürnbergA.P. Simopoulos, Washington, D.C.P. Singer, Petah TikvaN.W. Solomons, Guatemala CityP. Stehle, BonnI. Thorsdottir, ReykjavikK. Tontisirin, Nakhon PathomR. Uauy, SantiagoS. Villalpando, Cuernavaca MorelosT. Yoshikawa, KyotoA. Zittermann, Bad Oeynhausen
Founded 1959 as ‘Nutritio et Dieta’ by E. Azerad, H. Kapp and J. Trémolières. Continued by A. Wretlind (1961–1969). Continued by N. Zöllner (1970–1990) as ‘Nutrition and Metabolism’ (1970–1980), since 1980 integrating ‘Annales de la Nutrition et de l’Alimentation’, continued as ‘Annals of Nutrition and Metabolism’. Continued by G. Wolfram (1991–1999), Continued by I. Elmadfa (2000–2010)
An Official Journal ofInternational Union of Nutritional Sciences (IUNS)Federation of European Nutrition Societies (FENS)European Neutraceutical Association (ENA)Deutsche Gesellschaft für Ernährung (DGE)
2012EB 20.2.12GL 23.4.12GI 20.2.12
International Union of Nutritional Sciences (IUNS)
IUNS
Federation of European Nutrition Societies (FENS)
An Official Journal of
European Neutraceutical Association (ENA)
Deutsche Gesellschaft für Ernährung (DGE)
IUNS Editorial RepresentativeI. Elmadfa, Vienna
FENS Editorial RepresentativeD. Lairon, Marseilles
ENA Editorial RepresentativeM. Lamprecht, Graz
DGE Editorial ReresentativeH. Oberritter, Bonn
An excellent source of up-to-date information
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In high-performance sport an optimal diet and nu-tritional interventions can make the diff erence be-tween victory and defeat. In recent years, sport nutri-tion research has increased. This publication provides scientifi cally-based information with regard to the bioeffi cacy of trendy sport supplements and dietary approaches off the mainstream. International experts in the specifi c fi elds inform and clarify under which circumstances the application of certain supple-ments and nutritional interventions would be ben-efi cial, either for the performance or health of the athletes. A broad spectrum of recent topics in sport nutrition is provided: selected sport supplements aside of mainstream, nutritional interventions and athlete‘s health, hydration and fl uid balance and cur-rent aspects in exercise and exercise recovery. Finally, the publication concludes with recent information about the risk of supplementation and inadvertent doping. The book will be of benefi t to sport physicians and scientists, nutritionists, coaches and athletes, as well as to the sport nutrition trade and related industries.
Contents
Preface: Lamprecht, M.
Selected Off -Mainstream Sport Supplements• Beta-Alanine Supplementation in High-Intensity Exercise: Harris, R.C.; Sale, C.
• Arginine and Citrulline Supplementation in Sports and Exercise: Ergogenic Nutrients?: Sureda, A.; Pons, A.
• Dietary Nitrate and O2 Consumption during Exercise: Jones, A.M.; Bailey, S.J.; Vanhatalo, A.
• GABA Supplementation and Growth Hormone Response: Powers, M.
Nutritional Interventions and Athlete’s Health • Exercise, Intestinal Barrier Dysfunction and Probiotic Supplementation: Lamprecht, M.; Frauwallner, A.
• Pleuran (β-Glucan from Pleurotus ostreatus): An Eff ective Nutritional Supplement against Upper Respiratory Tract Infections?: Majtan, J.
Bovine Colostrum and Immune Function after Exercise: Davison, G.
• Supplementation with Mixed Fruit and Vegetable Concentrates in Relation to Athlethe’s Health and Performance: Scientifi c Insight and Practical Relevance: Lamprecht, M.
• Cherry Juice Targets Antioxidant Potential and Pain Relief: Kuehl, K.S.
• Impact of Milk Consumption and Resistance Training on Body Composition of Female Athletes: Josse, A.R.; Phillips, S.M.
Hydration and Fluid Balance• Glycerol Use in Hyperhydration and Rehydration: Scientifi c Update: van Rosendal, S.P.; Coombes, J.S.
• Salt and Fluid Loading: Eff ects on Blood Volume and Exercise Performance: Mora-Rodriguez, R.; Hamouti, N.
• Milk Protein and the Restoration of Fluid Balance after Exercise: James, L.
Current Aspects of Recovery• Chocolate Milk: A Post-Exercise Recovery Beverage for Endurance Sports: Pritchett, K.; Pritchett, R.
• Role of Supplementary L-Carnitine in Exercise and Exercise Recovery: Huang, A.; Owen, K.
Supplementation and Inadvertent Doping• Supplements and Inadvertent Doping – How Big Is the Risk to Athletes?: Judkins, C.; Prock, P.
Acute Topics in Sport Nutrition EditorsManfred Lamprecht
Medicine and Sport Science
Editors: J. Borms, M. Hebbelinck, A.P. Hills, T. Noakes
Vol. 59
Acute Topics in Sport NutritionEditor
M. Lamprecht
Karger – Medical and Scientifi c PublishersCH–4009 Basel, Switzerlandorders@karger.ch, f: +41 61 306 12 34www.karger.com
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Acute Topics in Sport Nutriton Editor: Lamprecht, M. (Graz)VIII + 156 p., 17 fi g., 6 tab., hard cover, 2012CHF 189.– / EUR 158.– / USD 222.00Prices subject to changeEUR price for Germany, USD price for USA onlyISBN 978–3–8055–9992–4e-ISBN 978–3–8055–9993–1
Medicine and Sport Science, Vol. 59Series Editors: Borms, J.; Hebbelinck, M.(Brussels); Hills, A.P. (Brisbane, Qld.); Noakes, T. (Cape Town) Listed in MEDLINE/PubMed
KI12474
Identifying novel interdisciplinary approaches
Adult
Nutrition
Nestlé Nutrition Institute Workshop Series | Vol. 73
Obesity Treatmentand Prevention: New Directions
Adam Drewnowski Barbara J. Rolls
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Obesity continues to be a major problem for global public health, aff ecting not only adults, but increas-ingly also adolescents and even young children. Moreover, obesity and diabetes are no longer limited to wealthy societies: rates are also rising in low- and middle-income countries.Summarizing some of the key issues in obesity treat-ment and prevention, this publication promotes novel and interdisciplinary approaches and explores cutting-edge ideas that span child development, nutrition, behavioral sciences, economics, geography and public health.Contributions suggest a sequence of steps that may result in new ways to address obesity at the person-al as well as at the population level: First, a clear un-derstanding of who becomes obese, where, and for what reason is needed. Second, the likely contribu-tions to overeating by the brain, biology, economics and the environment need to be identifi ed. Then, based on the understanding of disease etiology and its distribution by geography and by social strata, targeted yet comprehensive strategies for obesity prevention and treatment for both individuals and groups need to be developed.
Contents
Preface
Foreword
Contributors
Obesity Treatment: Challenges and Opportunities• Brain Reorganization following Weight Loss:
Rosenbaum, M.; Leibel, R.L.• Physical Activity and Weight Loss: Jakicic, J.M.• Dietary Strategies for Weight Management: Rolls, B.J.• Targeting Adipose Tissue Infl ammation to Treat the Underlying Basis of the Metabolic Complications of Obesity: Goran, M.I.; Alderete, T.L.
• Summary Discussion on Obesity Treatment: Challenges and Opportunities
New Directions for Prevention• The Gut Microbiome and Obesity: Hullar, M.A.J.; Lampe, J.W.• Starting Early: Obesity Prevention during Infancy: Birch, L.L.;
Anzman-Frasca, S.; Paul, I.M.• The Economics of Food Choice Behavior: Why Poverty and Obesity Are Linked: Drewnowski, A.
• The Importance of the Food and Physical Activity Environments: Oppert, J.-M.; Charreire, H.
• The Importance of Systems Thinking to Address Obesity: Finegood, D.T.
• Summary Discussion on New Directions for Prevention• Concluding Remarks
Obesity Treatment and Prevention: New DirectionsEditorsAdam DrewnowskiBarbara J. Rolls
Karger – Medical and Scientifi c PublishersCH–4009 Basel, Switzerlandorders@karger.com, f: +41 61 306 12 34www.karger.com
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Obesity Treatment and Prevention: New DirectionsEditors: Drewnowski, Adam (Seattle, Wash.); Rolls, B.J. (University Park, Pa.)XVI + 150 p., 12 fi g., 8 tab., hard cover, 2012CHF 50.– / EUR 42.– / USD 59.00Prices subject to changeEUR price for Germany, USD price for USA onlyISBN 978–3–318–02115–8e-ISBN 978–3–318–02116–5
Nestlé Nutrition Institute Workshop Series, Vol. 73ISSN 1664–2147e-ISSN 1664–2155
KI12684
Fiel
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of In
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; Ob
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; Ped
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Clin
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Nut
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Nestlé Nutrition Institute Workshop Series, Vol. 70ISSN 1664–2147 / e-ISSN 1664–2155
Meeting Micronutrient Requirements for Health and Development70th Nestlé Nutrition Institute Workshop, Cebu, March 2011 Editors: Bhutta, Z.A. (Karachi); Hurrell, R.F. (Zurich); Rosenberg I.H. (Boston, Mass.)XVIII + 194 p., 24 fi g., 16 tab., hard cover, 2012CHF 50.– / EUR 42.– / USD 59.00Prices subject to changeEUR price for Germany, USD price for USA onlyISBN 978–3–318–02111–0 / e-ISBN 978–3–318–02112–7
PediatricN
utrition
Nestlé Nutrition Institute Workshop Series | Vol. 70
Meeting Micronutrient Requirements for Health and Development
Zulfiqar A. Bhutta Richard F. HurrellIrwin H. Rosenberg
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2658
Micronutrients and their signifi cance in pregnancy and early childhood
Meeting Micronutrient Requirements for Health and DevelopmentEditorsZulfi qar A. BhuttaRichard F. HurrellIrwin H. Rosenberg
Meeting macro- and micronutrient require-ments during pregnancy and early childhood is crucial for short- and long-term health and cognitive function. Meta-analyses confi rm that supplementation or fortifi cation of food with the ‘big four’ (vitamin A, iron, zinc, and iodine) is effi cacious to reduce the risk of infectious disease and improves growth and cognitive outcome. More recently, folate and vitamin B12 defi ciencies during pregnancy have been shown to be associated with poor neurodevel-opmental outcome and childhood obesity. The papers collected in the book at hand ad-dress the fact that maternal and fetal defi cien-cies can induce inadequate metabolic pro-gramming in the off spring, with increased risk for non-communicable diseases later in life. World-renowned experts in the fi elds of epide-miology and nutritional intervention met with those in genetics, epigenetics, and metabolic outcome to clarify the pathogenesis of micro-nutrient defi ciencies in pregnancy and child-hood, preventive methods and strategies, and opportunities for treatment.
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Contents
Introduction to Micronutrient RequirementsGlobal Micronutrient Defi ciencies in Childhood
and Impact on Growth and Survival: Challeng-es and Opportunities: Imdad, A.; Bhutta, Z.A.
Micronutrients in the Treatment of Stunting and Moderate Malnutrition: Penny, M.E.
Discussion on Micronutrient Requirements: Solomons, N.W.
Zinc in Maternal and Child HealthZinc Requirements: Assessment and Population
Needs: Hambidge, K.M. et al.Role of Zinc in Child Health and Survival:
Black, R.E.; Fischer Walker, C.Discussion on Zinc in Maternal and Child Health:
Wasantwisut, E.
Multiple Micronutrient Defi ciencies in Pregnancy
Global Burden and Signifi cance of Multiple Micronutrient Defi ciencies in Pregnancy: Darnton-Hill, I.
Intervention Strategies to Address Multiple Micronutrient Defi ciencies in Pregnancy and Early Childhood: Imdad, A.; Bhutta, Z.A.
Summary on Micronutrient Requirements and Defi ciencies in Maternal and Child Nutrition: Bhutta, Z.
Vitamin A in Childhood: Evidence and Controversy
Vitamin A Supplementation, Infectious Disease and Child Mortality: A Summary of the Evidence: Thorne-Lyman, A.; Fawzi, W.W.
Issues and Controversies with Vitamin A in Childhood: Murguía Peniche, M.T.
Discussion on Vitamin A Supplementation in Childhood: Bhatia, J.
IronInfl uence of Infl ammatory Disorders and Infection
on Iron Absorption and Effi cacy of Iron-Fortifi ed Foods: Hurrell, R.F.
Safety of Iron Fortifi cation and Supplementation in Malaria-Endemic Areas: Brittenham, G.M.
Discussion on Iron: Lynch, S.Summary on Vitamin A and Iron: Hurrell, R.F.
IodineAre Weaning Infants at Risk of Iodine Defi ciency
Even in Countries with Established Iodized Salt Programs? Zimmermann, M.B.
Current Challenges in Meeting Global Iodine Requirements: Eastman, C.J.; Jooste, P.
Folate, Vitamin B12 and BrainFolate and Vitamin B12: Function and Importance
in Cognitive Development: Troen, A.M.Discussion on Folate and Vitamin B12 Importance
in Cognitive Development: Rosenberg, I.H.Pros and Cons of Increasing Folic Acid and Vitamin
B12 Intake by Fortifi cation: Allen, L.H.Discussion on Vitamin B12 and Folic Acid
Fortifi cation: Rosenberg, I.H.Summary on Iodine Folate and Vitamin B12:
Rosenberg, I.H.
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ISSN Print Edition: 0250–6807ISSN Online Edition: 1421–9697
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World Review of Nutrition and Dietetics, Vol. 104Series Editor: Koletzko, B. (Munich)ISSN 0084–2230 / e-ISSN 1662–3975
Semba, R.D. (Baltimore, Md.)The Vitamin A StoryLifting the Shadow of DeathXVI + 208 p., 41 fi g., 2 in color, 9 tab., hard cover, 2012CHF 88.– / EUR 73.– / USD 104.00Prices subject to changeEUR price for Germany, USD price for USA onlyISBN 978–3–318–02188–2e-ISBN 978–3–318–02189–9
World Review of Nutrition and Dietetics
Editor: B. Koletzko
Vol. 104
R.D. Semba
The Vitamin A StoryLifting the Shadow of Death
KI 1
2669
Intriguing reading for specialists and the interested public alike
Richard D. Semba
The Vitamin A StoryLifting the Shadow of Death
This book shows how vitamin A defi ciency – before the vitamin was known to scientists – aff ected mil-lions of people throughout history. It is a story of sailors and soldiers, penniless mothers, orphaned infants, and young children left susceptible to blindness and fatal infections. We also glimpse the fortunate ones who, with ample vitamin A-rich food, escaped this elusive stalker. Why were people going blind and dying? To unravel this puzzle, sci-entists around the world competed over the course of a century. Their persistent eff orts led to the iden-tifi cation of vitamin A and its essential role in health. As a primary focus of today’s international public health eff orts, vitamin A has saved hundreds of thousands of lives. But, we discover, they could save many more were it not for obstacles erected by political and ideological zealots who lack a his-torical perspective of the problem. Although exhaustively researched and document-ed, this book is written for intellectually curious lay readers as well as for specialists. Public health pro-fessionals, nutritionists, and historians of science and medicine have much to learn from this book about the cultural and scientifi c origins of their disciplines. Likewise, readers interested in military and cultural history will learn about the interaction of health, society, science, and politics. The author’s presentation of vitamin A defi ciency is likely to become a classic case study of health disparities in the past as well as the present.
Contents
PrefaceGlossary
Chapter 1Vitamin A Defi ciency in Nineteenth Century Naval Medicine
Chapter 2Paris in the Time of François Magendie
Chapter 3Deprivation Provides a Laboratory
Chapter 4Free but Not Equal
Chapter 5The Long, Rocky Road to Understanding Vitamins
Chapter 6Milk, Butter, and Early Steps in Human Trials
Chapter 7Rise of the ‘Anti-Infective Vitamin’
Chapter 8Vitamin A Defi ciency in Europe’s Former Colonies
Chapter 9Saving the Children: Rescue Missions against Strong Undertow
AppendixNight Blindness Among Black Troops and White Troops in the US Civil War
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Contents
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© 2012 S. Karger AG, Basel
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Aims and ScopeThe journal focuses on human nutrition and metabo-lism and related areas, including experimental stud-ies and basic science that can inform human nutrition science. We welcome manuscripts describing obser-vational and intervention studies as well as basic sci-ence reports on the topics of foods, diets and dietary supplements, nutrigenomics and genetics related to metabolism, on energy metabolism, macro- and mi-cronutrients including vitamins and minerals, biofunc-tional compounds, dietetics, obesity, clinical nutrition, social sciences and health economy as related to nutri-tion and metabolism and nutrition policy. Laboratory-based science may include descriptions of relevant ex-perimental models. In addition to Original Papers, the journal will publish Review Articles on topical subjects, Systematic Reviews, short Commentaries and View-point articles that may address current controversies, short Meeting Reports, Letters to the Editor, and An-nouncements/Society News. The journal will also pub-lish Supplements with proceedings from internation-ally relevant conferences on nutrition and metabolism.
SubmissionManuscripts written in English are considered and should be submitted online at
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Authors may suggest up to four Referees who have expert knowledge on the subject. Suggested Refer-ees should not be from the same institution, not have published with the authors during the last 5 years, and should not be prejudiced.
Should you experience problems with your submission, please contact
Prof. Dr. B. KoletzkoDiv. Metabolic and Nutritional MedicineDr. von Hauner Children’s HospitalLudwig-Maximilians-University of MunichLindwurmstrasse 4D–80337 Munich (Germany)Tel. +49 89 5160 2826E-Mail ANM@med.uni-muenchen.de
ConditionsAll manuscripts are subject to editorial review. Manu-scripts are received with the explicit understanding that they are not under simultaneous consideration by any other publication. Submission of an article for publica-tion implies transfer of the copyright from the author to the publisher upon acceptance. Accepted papers be-come the permanent property of ‘Annals of Nutrition and Metabolism’ and may not be reproduced by any means, in whole or in part, without the written consent of the publisher. It is the author’s responsibility to ob-tain permission to reproduce illustrations, tables, etc. from other publications.
Types of ArticlesThe journal consists of the following sections:
Original Papers are full-length research papers which will be considered for the journal. Articles cover top-ics relevant to clinical studies. Basic and experimental work appear only if directly related to clinical issues (max. 2,500 words).
Review Articles/Systematic Reviews are comprehensive, state-of-the-art papers of important clinical problems. Reviews may be invited by the Editor or they may be unsolicited views (max. 5,000 words).Commentaries and Viewpoint of an editorial nature may be submitted to the journal. In these communica-tions, usual manuscript subdivisions do not apply, and a summary statement is not needed; however, a very brief reference list may be included (max. 500 words).
Meeting Reports are brief summaries of scientific meet-ings in the field of nutrition and metabolism. Authors should write a letter to the Editors inquiring about po-tential interest before submitting the paper. (max. 1,500 words).
Letters to the Editor are encouraged if they directly concern articles previously published in this journal or clinical subjects related to the matters discussed. The editor reserves the right to submit copies of such letters to the authors of the articles concerned prior to publication in order to permit them to respond in the same issue of the journal (max. 500 words).
Editorials are usually invited by the Editor (max. 1,000 words). Please send suggestions to the Editor.
Authors are referred to the uniform requirements for manuscripts submitted to biomedical journals (http://www.icmje.org/ethical_1author.html) for fur-ther guidance.
Conflicts of InterestAuthors are required to disclose any sponsorship or funding arrangements relating to their research and all authors should disclose any possible conflicts of inter-est. Conflict of interest statements will be published at the end of the article.
EthicsPublished research must comply with the guidelines for human studies and animal welfare regulations. Authors should state that subjects have given their informed consent and that the study protocol has been approved by the institute’s committee on human research. Fur-ther, they should also state that animal experiments conform to institutional standards.
Plagiarism PolicyPlagiarism is misrepresenting somebody else’s pub-lished intellectual work-product as your own (Note, this definition excludes ‘self-plagiarism’). In short, it is a misuse of source material. Whether intentional or unintentional, plagiarism is a serious violation of the Annals of Nutrition and Metabolism policy. Periodi-cally, manuscripts are screened for plagiarism and if your manuscript is found to be consistent with what the Editors define* as plagiarism prior to review of the manuscript then:
1) it will be rejected without review and the author(s) notified as such with a chance for rebuttal.
If a manuscript is found to contain evidence of plagia-rism after acceptance and/or publication then:
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If the rebuttal arguments are not found to be satisfac-tory, as judged by the Editors, the manuscript will be rejected and the author sanctioned from publishing ad-ditional papers in the Journal for a period to be deter-mined by the Editorial Board. The period of sanction imposed is dependent on the magnitude of plagiarism with a minimum sanction of one year.
If a manuscript already published in the Journal is found to exhibit evidence of plagiarism as defined by the Editors*, then we will request a retraction.*Definition of plagiarism – a 25% similarity in theResults or Discussion that exactly reproduces anotherpaper.
ArrangementTitle page: The first page of each paper should indi-cate the title, the authors’ names, the institute where the work was conducted, and a short title for use as running head.
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Key words: For indexing purposes, a list of 3–10 key words in English is essential.
Abstract: Each paper needs an abstract of up to 200 words. It should be structured as follows:Background/Aims: What is the major problem that
prompted the study?Methods: How was the study performed?Results: Most important findings?Conclusion: Most important conclusion?
Footnotes: Avoid footnotes.
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References: In the text, identify references by Arabic numerals [in square brackets]. Material submitted for publication but not yet accepted should be noted as ‘un-published data’ and not be included in the reference list. The list of references should include only those publi-cations which are cited in the text. Do not alphabet-ize; number references in the order in which they are first mentioned in the text. The surnames of the authors followed by initials should be given. There should be no punctuation other than a comma to separate the authors. Preferably, please cite all authors. Abbreviate journal names according to the Index Medicus system. Also see International Committee of Medical Journal Editors: Uniform requirements for manuscripts sub-mitted to biomedical journals (www.icmje.org).
Examples(a) Papers published in periodicals: Chatel J-M, Bernard H, Orson FM: Isolation and characterization of two complete Ara h 2 isoforms cDNA. Int Arch Allergy Immunol 2003;131:14–18.(b) Papers published only with DOI numbers:Theoharides TC, Boucher W, Spear K: Serum inter-leukin-6 reflects disease severity and osteoporosis in mastocytosis patients. Int Arch Allergy Immunol DOI: 10.1159/000063858.(c) Monographs: Matthews DE, Farewell VT: Using and Understanding Medical Statistics, ed 3, revised. Basel, Karger, 1996.
Guidelines for Authors
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© 2012 S. Karger AG, Basel
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Guidelines for Authors
(d) Edited books: DuBois RN: Cyclooxygenase-2 and colorectal cancer; in Dannenberg AJ, Dubois RN (eds): COX-2. Prog Exp Tum Res. Basel, Karger, 2003, vol 37, pp 124–137.
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Supplementary MaterialSupplementary material is restricted to additional data that are not necessary for the scientific integrity and conclusions of the paper. Please note that all supple-mentary files will undergo editorial review and should be submitted together with the original manuscript. The Editors reserve the right to limit the scope and length of the supplementary material. Supplementary material must meet production quality standards for Web publication without the need for any modifica-tion or editing. In general, supplementary files should not exceed 10 MB in size. All figures and tables should have titles and legends and all files should be supplied separately and named clearly. Acceptable files and for-
mats are: Word or PDF files, Excel spreadsheets (only if the data cannot be converted properly to a PDF file), and video files (.mov, .avi, .mpeg).
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NIH-Funded Research The U.S. National Institutes of Health (NIH) mandates under the NIH Public Access Policy that final, peer-re-viewed manuscripts appear in its digital database with-in 12 months of the official publication date. As a ser-vice to authors, Karger submits the final version of your article on your behalf to PubMed Central. For those se-lecting our premium Author’s ChoiceTM service, we will send your article immediately upon publishing, accel-erating the accessibility of your work without the usual embargo. More details on NIH’s Public Access Policy is available at http://publicaccess.nih.gov/FAQ.htm#a1
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vided the following conditions are met: Articles may not be used for commercial purposes, must be linked to the publisher’s version, and must acknowledge the publisher’s copyright. Authors selecting Karger’s Au-thor’s ChoiceTM feature, however, are also permitted to archive the final, published version of their article, which includes copyediting and design improvements as well as citation links.
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A new vision to understanding medicine
Handbook of Clinical Gender Medicine
XVI + 522 p., 62 fi g., 4 in color, 63 tab., soft cover, 2012CHF 69.– / EUR 51.– / USD 69.00ISBN 978–3–8055–9929–0e-ISBN 978–3–8055–9930–6
Prices subject to changeEUR price for Germany, USD price for USA only
AGGTATCCAATGATAAGCATGATAAAAGCTCACGGTATCCAATGATAAGCATCACGGTATCATCCAATGATAAGCATGATATTTATCCAATGATAAGCATCACGGTATATCCAATGATAAGCATGATAAGCTCACGGTATCCAAAATGATAAGCATCACGGT
AGCATGATAAGCTCACGGTATCCAATATGATAAGCATCACGGTATCCAATGATAAGCATGATATAAGCTCACGGTATCGAGCATCACGGTATCCAATGATAAGCATTGATAAGCGTG ATCCAATGATAAGCATCACGGTATCCCCAATGATAAGCATG
GGGTATCCAATGATAAGCATCACGGTATCCCAATGATAAGCATGATAAGCCACGGTATCCAATGAGATAAGCATCACGGGATAAGCATGATAAGCTCACGGTATCCAATGTGATAAGCATCACGGTATCCAATGATAAGCATGATATAAGCTCACGGAAGCATCACGGTATCCAATGATAAGCATGATAAAGCTCACGGTATCCAATGATAAGCATCACGGTATCTCCAATGATAA
AAGCTCACGGTATCCAATGATAAGCATCACGGTATATCCAATGATAAGCATGATAAGCTCACGGTATCCAAATGATAAGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCACAATGATAAGCATCACGGTATCCAATGATAAGCATATGATAAGCCAATGATAAGCATCACGGTATCCAATGATAAGCATGGATAAGCTCAA CGGTATCCAATGATAAGCATCACGGGGTATC
AGCATGATAAGCTCACGGTATCCAATGATAAGCATCACACGGTATCCAATGATAAGCATGATAAGCTCACGGTATATCAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGGGTATCCAATGATAAGCATCACGGTATCCAATGAATATAA
AAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGAGATAAGCATGATAAGCTCACGGTATCAGCATGATAATTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATATAAGCTCACGGTATCCAATGATAAGCATCACGGT
AGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCTCCAATGATAAGCATGATAAGCTCACGGTATCAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCCAATGATAAGA CATCACGGTATCCAATGATAA
GGAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCACATGATAAGTCACGGTATCCAATGATAAGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACACGGTATCCAATGATAAGCATGATAAGCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATATCCAATGATAAGCATCACGGTATC
CAGCATGATAAGCCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAATAAGCATGATAAGCTCACGGTATCCAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAAAGCATCACGGTATCCAATGATAA
AAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGAGCTCACGGTATCCAATGATAAGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCTCCAATGATAAGCATGATAAGCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGGATAAGCATCACGGTATC
AGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGAGATAAGCTCACGGTATCAAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACACGGTATCCAATGATAA
AAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGGTATCCAATGATAAGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATATAAGCATGATA AAGCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATATCACGGTATC
AGCATGATAAGCGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTGTATCCAATGAGGTATCCAATGATAAGCATGATAAGCCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCGCATGATAATTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATATCACGGT
AGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGGTATCAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGAGATAA
AAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATTAAAGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGAG
CAATGATAAGCATCACGGTATCCAATGATAAGAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATC
AAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAG
CAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGTCACGGTATCCAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAA
GGAGCCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAG
CAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATC
ATGATAAAATCCAGGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGAGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATA
TATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACAGCATCACGGTATCCAATGATAAGCATGATAAGCGTATGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCCACGGTATCCAATGATAAGCATCACGGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGAGTATCCAATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAATATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCAGCATGATA
TAATCCCAAATGATTAACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCGGTATCCAATGAATAAGCATGATAAA CTCACGGTA CTCCAATGATAAGCATCACGGTATCCAATGATAAGCATGCCAAATGA AAGCCATCACGGTAT CAATGATAAGCAATG
GCATGTGATAAGGATAAGGGTATCGGTATCTATCCCAATGCATCACGGTATCCGCATCACGGTATCC
CACGGTATCCAATGCAACGGTATCCCAATGACGGACGGTACGGTACGGTACGGACGGTACGGTCGCGCGACGGACCA TGAGAGAGATGATGATTGATGATGATGATATAAAAAAAAGAGAAAAAAAAAAAA
AGCCATTCACGGGTATATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCCAATGATAAGCATCACGGTATCCAAAGCATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTAAGCATAAGGCATCACGGGTATCCAATGATAAGCATGATAAGCTCAACGGTATCCAATGATAAGCATCACGGTAAAAAAACCCCCGGCCGGGGGGG CCACAAAAAAAAAAATATA
AGCATAG CACGGGTATCCAATGATAAGCATGATAAGAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATTGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAATGATAAGCATCACGGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAA
TAAAGCAATGATACAATGATTAATGATAAGCTGATAAGCCATTGATAAAGATCCAATGATAAGATTCCAATGATATAAG
AGCATGATAAGCTCAGCCATGATAAGGCTCACGGAAGCATGATAGCATGATATCACGGTATCACGGTGTGTTGTTTATCCAATCCAATCCAATCCATCCAATCCAATCCATCCATCCACCATCCATCCAATCCACCACCAAA AAAAAAAAAACGGACGACGGACGACGGACGGACGACGGACGGACGGGGACGGACGACGACGA GCAGCACGCACAGCACACACACACAGCAGCATGTGTGTGATGATGATTGATGTGATGAGTGAGTG
Handbook of Clinical Gender MedicineEditors
Karin Schenck-GustafssonPaula R. DeColaDonald W. PfaffDavid S. Pisetsky
S. Karger AG, P.O. BoxCH–4009 Basel
(Switzerland) Fax. +41 61 306 12 34
E-Mail orders@karger.chwww.karger.com
Editors: Karin Schenck-Gustafsson (Stockholm), Paula R. DeCola, Donald W. Pfaff (New York, N.Y.), David S.Pisetsky (Durham N.C.)
In well-referenced chapters, experts cogently and concisely explain how the incorporation of gender issues into research can aff ect the medical understanding and treatment of heart disease, osteopo-rosis, arthritis, pain as well as malaria among other conditions.
This intriguing and unique medical textbook provides readers with a valuable new perspective on how to incorporate gender issues into the diff erent branches of medicine.
More information and sample essays at:
www.karger.com/Gender_Medicine
Reaching beyond traditional nutrition support
The easiest way to order : w w w.karger.com/wrund
The care of ICU patients has seen many improve-ments over the years, both with regard to technical aspects and supportive measures. The fi rst part of this book analyzes nutritional support at various levels, ranging from the cell level to the whole-body aspect; drawing on recent prospective randomized studies, the authors propose a new approach for oral, enteral and/or parenteral nutrition. The second part under-lines the interference between nutrition and out-come to reach recovery, giving to this fi eld an in-creased importance for better short- and long-term management: The best glucose control, individual-ized nutritional support and the avoidance of harm-ful interferences is extensively discussed. The fi nal part deals with patients suff ering from multi-organ failure and the need for a better understanding of the interactions between disease and nutrition. Identifi -cation of the metabolic condition of the patient, existence or not of evidence-based medicine, expert opinion, treatment opportunities and the case man-ager recognizing threats are all integrated to reach the appropriate decision. This last part will help the reader to untangle the complexity of the ICU patient of the 21st century and to propose a personalized nutritional support process.
Contents
List of ContributorsPreface: Singer, P.
Requirements, Routes of Administration and Prescription• From Mitochondrial Disturbances to Energy Requirements: Singer, P.
• Protein Metabolism and Requirements: Biolo, G.• How to Choose the Route: Grecu, I.• How to Prescribe Nutritional Support Using Computers: Berger, M.M.
• Oral Feeding: Alvárez-Falcón, A.; Ruiz-Santana, S.• Enteral Nutrition: Anbar, R.• Parenteral Nutrition: Thibault, R.; Pichard, C.
How Can Nutrition Interfere with Outcome?• Can Nutrition Support Interfere with Recovery from Acute Critical Illness? Schulman, R.C.; Mechanick, J.I.
• Glucose Control: Preiser, J.-C.• Glutamine: Kim, M.; Wischmeyer, P.E.• Leucine and Citrulline: Two Major Regulators of Protein Turnover: Cynober, L.; de Bandt, J.-P.; Moinard, C.
Organ-Targeted Nutrition• The Surgical/Trauma Patient: Weimann, A.• Nutrition and Sepsis: Cohen, J.; Chin, W.D.N.• The Renal Failure Patient: Druml, W.• n–3 Fatty Acids and γ-Linolenic Acid Supplemen-tation in the Nutritional Support of Ventilated Patients with Acute Lung Injury or Acute Respira-tory Distress Syndrome: Lev, S.; Singer, P.
• Obesity: Frankenfi eld, D.C.• Nutritional Imbalances during Extracorporeal Life Support: Kagan, I.; Singer, P.
• Nutrition in Pancreatitis: McClave, S.A.• Which Nutritional Regimen for the Comorbid Complex Intensive Care Unit Patient? Singer, P.; Weinberger, H.; Tadmor, B.
• Nutrition Support for Wound Healing in the Intensive Care Unit Patient: Theilla, M.
Nutrition in Intensive Care: Beyond PhysiologyEditorPierre Singer105
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World Review of Nutrition and Dietetics
Editor: B. Koletzko
Vol. 105
Nutrition in Intensive Care Medicine: Beyond PhysiologyEditor
P. Singer
Karger – Medical and Scientifi c PublishersCH–4009 Basel, Switzerlandorders@karger.ch, f: +41 61 306 12 34www.karger.com
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Nutrition in Intensive Care: Beyond PhysiologyEditor: Singer P. (Petah Tikva)XII + 194 p., 18 fi g., 26 tab., hard cover, 2013CHF 196.– / EUR 163.– / USD 231.00Prices subject to changeEUR price for Germany, USD price for USA onlyISBN 978–3–318–02227–8e-ISBN 978–3–318–02228–5
World Review of Nutrition and Dietetics, Vol. 105Series Editor: Koletzko, B. (Munich)Listed in MEDLINE/PubMed
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Quality and Safety in Infant NutritionEditors: Koletzko, B. (Munich); Shamir, R. (Tel Aviv)46 p., 3 fi g., 4 tab., soft cover, 2012CHF 29.– / EUR 24.– / USD 34.00Prices subject to changeEUR price for Germany, USD price for USA onlyISBN 978–3–318–02178–3e-ISBN 978–3–318–02179–0
Annals of Nutrition and MetabolismVol. 60, No. 3 (2012)Included in subscription
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Quality and Safety in Infant NutritionEditorsB. KoletzkoR. Shamir
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Contents
Quality and Safety Aspects of Infant Nutrition: Koletzko, B.; Shamir, R.; Ashwell, M.; on behalf of the Early Nutrition Academy (ENA) and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN)
Thiamine-Defi cient Infant Formula: What Happened and What Have We Learned? Shamir, R.
Current Safety Standards in Infant Nutrition – A European Perspective: Hernell, O.
Safety Standards in Infant Nutrition: A United States Perspective: Bier, D.M.
Preclinical Assessment of Infant Formula: Lönnerdal, B.
Clinical Safety Assessment of Infant Nutrition: Fewtrell, M.S.
The Role of Systematic Data Reviews in Safety Assessment of Infant Nutrition: Szajewska, H.
Quality Control throughout the Production Process of Infant Food: Hamrin, P.; Hoeft, B.
Safety Aspects in Preparation and Handling of Infant Food: Turck, D.
Non-Breast Milk Feeding in Developing Countries: Challenge from Microbial and Chemical Contaminants: Weisstaub, G.; Uauy, R.
International Union of Nutritional Sciences (IUNS)
Federation of European Nutrition Societies (FENS)
IUNS
An Offi cial Journal of
S. KargerMedical and Scientifi c PublishersBasel . Freiburg . Paris . London . New York . New Delhi . Bangkok . Beijing . Tokyo . Kuala Lumpur . Singapore . Sydney
Ann Nutr Metab60(3) 175–220 (2012) 60 | 3 | 12 print
ISSN 0250–6807onlinee-ISSN 1421–9697
www.karger.com/anm
ISBN 978–3–318–02178–3
Quality and Safety in Infant Nutrition
EditorsB. Koletzko, MunichR. Shamir, Tel Aviv
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An interdisciplinary journal on human and clinical nutrition
Annals of Nutrition and Metabolism is a leading international peer-reviewed journal for sharing information on human nutrition, metabolism and related fi elds, covering the broad and mul-tidisciplinary nature of science in nutrition and metabolism. The journal focuses on human nu-trition and metabolism and related areas, includ-ing experimental studies and basic science that can inform human nutrition science. We wel-come manuscripts describing observational and intervention studies as well as basic science re-ports on the topics of foods, diets and dietary supplements, nutrigenomics and genetics re-lated to metabolism, on energy metabolism, macro- and micronutrients including vitamins and minerals, biofunctional compounds, dietet-ics, obesity, clinical nutrition, social sciences and health economy as related to nutrition and me-tabolism and nutrition policy. Laboratory-based science may include descriptions of relevant ex-perimental models. In addition to Original Pa-pers, the journal will publish Review Articles on topical subjects, Systematic Reviews, short Com-mentaries and Viewpoint articles that may ad-dress current controversies, short Meeting Re-ports, Letters to the Editor, and Announcements/Society News. The journal will also publish Sup-plements with proceedings from internationally relevant conferences on nutrition and metabo-lism.
Selected contributions• Glycemic Responses of Patients with Type 2 Diabetes to Individual Carbohydrate-
Rich Foods and Mixed Meals: Robert, S.D.; Ismail, A.A.-S. (Kelantan)
• Vitamin D in Relation to Myocardial Structure and Function after Eight Years of Follow-Up: The Hoorn Study: van Ballegooijen, A.J.; Snijder, M.B.; Visser, M.; van den Hurk, K.; Kamp, O.; Dekker, J.M.; Nijpels, G. (Amsterdam); Stehouwer, C.D.A.; Henry, R.M.A. (Maastricht); Paulus, W.J.; Brouwer, I.A. (Amsterdam)
• Health Eff ects Related to Low Vitamin D Concentrations: Beyond Bone Metabolism: Moreno, L.A. (Zaragoza); Valtueña, J. (Madrid); Pérez-López, F. (Zaragoza); González-Gross, M. (Madrid/Bonn)
• Upregulation of Hepatic 11-Hydroxysteroid Dehydrogenase-1 Expression in Calcium-Defi cient Rats: Takaya, J.; Iharada, A.; Okihana, H.; Kaneko, K. (Moriguchi)
• Diet-Dependent Net Endogenous Acid Load of Vegan Diets in Relation to Food Groups and Bone Health-Related Nutrients: Results from the German Vegan Study: Ströhle, A. (Hannover); Waldmann, A. (Lübeck); Koschizke, J. (Hannover); Leitzmann, C. (Giessen); Hahn, A. (Hannover)
• Eff ect of Selenium Supplementation on Glutathione Peroxidase and Catalase Activities in Senescent Cultured Human Fibroblasts: Ghneim, H.K.; Al-Sheikh, Y.A. (Riyadh)
• Role of Nutritional Status in Predicting the Length of Stay in Cancer: A Systematic Review of the Epidemiological Literature: Gupta, D.; Vashi, P.G.; Lammersfeld, C.A.; Braun, D.P. (Zion, Ill.)
• Eff ects of Monounsaturated Fatty Acids on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis: Schwingshackl, L.; Strasser, B.; Hoffmann, G. (Hall in Tirol)
Annals of Nutrition and Metabolism2013: Volumes 62, 634 issues per volumeLanguage: EnglishISSN 0250–6807 (print)ISSN 1421–9697 (online)
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