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Univ.-Prof. Dr. Dr.h.c. Rudolf Bauer

Personal Information

Born on 30. September 1956 in Obertaufkirchen, Germany

Married with Christine Bauer, three sons: Maximilian, Thomas and Sebastian (*1988, 1991, 1994), one daughter: Franziska (*1997)

Education

1976-1980 Studies of “Pharmacy” at University of Munich, Germany

1980-1984 Ph.D. dissertation: Pharmaceutical Biology, University of Munich; supervisor Prof. Dr. H. Wagner

1984-1990 Post doc and finally Habilitation in Pharmaceutical Biology, Privatdozent, Faculty of Chemistry and Pharmacy, University of Munich

Professional Experience

1980-1993 Employment as Scientific Assistant, Akademischer Rat and Oberrat at the Institute for Pharmaceutical Biology, University of Munich

1993-2002 University Professor (C3) in Pharmaceutical Biology at the Faculty of Mathematics and Natural Sciences, University of Düsseldorf, Germany

since 2002 Full Professor in Pharmacognosy at the Faculty of Natural Sciences, University of Graz

2002-2004 Head of the Institute of Pharmacognosy, University of Graz

2004-2020 Head of the Institute of Pharmaceutical Sciences, University of Graz

since 2020 Deputy Head of the Institute of Pharmaceutical Sciences and Head of the Department of Pharmacognosy, University of Graz

Selected Career-related Activities

1987 Post doctoral studies at the Department of Ecology and Biology, University of California, Irvine, U.S.A. (Prof. Dr. E. Rodriguez)

1990/91 Guest Professor at the Institute of Pharmacognosy, University of Innsbruck

1996-2015 Co-Editor of Planta Medica

2002-2007 President of the Society for Medicinal Plant Research (GA)

since 2005 Member of the Expert Group 13A of the European Pharmacopoeia Commission

since 2008 Member of the TCM Working Group of the European Pharmacopoeia Commission

2005-2015 Member of the Advisory Board on Traditional Asian Medicine (TAM) of the Austrian Minister of Health

since 2007 Head of the TCM Research Center Graz, Herbal Medicine Research

since 2010 Member of the Academic Committee of International Science & Technology Cooperation Base of Heilongjiang University of Chinese Medicine, Harbin, China

2010-2015 Member of the Biology and Medicine Panel of the Hong Kong Research Grants Council

since 2010 Vice-Chairman of the Expert Committee of TCM Pharmaceutical Analysis of the World Federation of Chinese Medicine Societies

2012-2014 Founding president of The Good Practice in TCM Research Association ∙

2015-2017 President of the International Society of Ethnopharmacology

since 2015 Vice-Chairman of the Expert Committee of the 1st Board of Specialty Committee of Multidimensional Evaluation of Genuine Medicinal Material of World Federation of Chinese Medicine Societies

since 2014 Associate Editor-in-chief of the World Journal of Traditional Chinese Medicine

since 2017 Chairman of the working group on TCM of the European Pharmacopoeia Commission

Member of the Editorial Board of Journal of Ethnopharmacology, Frontiers in Pharmacology (Associate Editor

in Ethnopharmacology), Clinical Phytoscience, Chinese Journal of Natural Medicines (Associate Editor-in-chief), Chinese Herbal Medicines (Associate Editor-in-chief), Chinese Journal of Integrative Medicine, etc.

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Publishing Activities (orcid.org/0000-0002-0057-5547)

Author of 388 scientific publications and 6 patents;

h-index 55 (self citations excluded, Research Gate 07.01.2021)

Editor and co-editor of several books

Awards

1990 Egon-Stahl-Award of the Society for Medicinal Plant Research

1994 Cipla Distinguished Fellowship in Pharmaceutical Sciences of the Department of Chemical Technology der University of Bombay

1996 International Award of the Belgian Society of Pharmaceutical Sciences

2000 Honorary Guest Professor of the School of Chinese Materia Medica of the Beijing University of Chinese Medicine

2006 Honorary Guest Research Fellow of the Guangxi Botanical Garden of Medicinal Plants and the Institute of Guangxi Medicinal Plants

2010 Norman R. Farnsworth Excellence in Botanical Research Award of the American Botanical Council

2011 Guest Professor of Institute of Medicinal Plant Development (IMPLAD), China Academy of Medical Sciences, Beijing

2011 Guest Professor of Chengdu University of Traditional Chinese Medicine

2011 Guest Professor of Heilongjiang University of Chinese Medicine, Harbin

2011 Guest Professor of Changchun University of Chinese Medicine

2016 Distinguished Achievement Award of the International Conference on the Science of Botanicals, Oxford, MS (USA), in recognition of the contributions to promote the quality control and global safety of herbal medicines, sponsored by Waters Corporation

2017 Qihuang International Prize of China Association of Chinese Medicine for the great contributions and achievements in the field of scientific research and development in Chinese medicine (China)

2017 Outstanding Contribution Award der Shanghai International Conference on TCM and Natural Medicine

2018 Outstanding International Scientist Award (Pranab Banerji Memorial Award) der Society for Ethnopharmacology India (SFE) for outstanding contributions in the field of ethnobotany, ethnopharmacology and medicinal plant research.”

2019 Award for Outstanding Contribution in TCM Analysis & Quality Standards of the TCM Pharmaceutical Analysis Specialty Group of the World Federation of Chinese Medicine Societies

2019 Varro E. Tyler Award of the American Society of Pharmacognosy

2019 Honorary Doctorate of the Faculty of Philosophy at University of Helsinki, Finland

Main research areas:

• Quality control and standardization of herbal drugs and herbal medicinal products including Chinese herbal drugs

• Isolation and structure elucidation of biologically active plant constituents

• Pharmacological screening of plant constituents with anti-inflammatory activity (e.g. inhibition of COX, NFkB, iNOS)

• Isolation and structure elucidation of plant constituents with anticancer and antimicrobial activity

• Phytochemical and pharmacological investigation of Echinacea species

• Pharmakokinetic studies with herbal medicinal products

• Plant metabolomics based drug discovery

• Interaction of herbal medicinal products with gut microbiota

Contact data:

Univ.-Prof. Dr. Dr.h.c. Rudolf Bauer Institute of Pharmaceutical Sciences Karl-Franzens-Universitaet Graz Universitaetsplatz 4, 8010 Graz, Austria Phone: ++43-(0)316-380-8700 Fax: ++43-(0)316-380-9860 E-mail: rudolf.bauer@uni-graz.at http://www.kfunigraz.ac.at/phgwww/

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Supervised PhD Theses

Univ.-Prof. Dr. Dr. h.c. Rudolf Bauer as by 16.09.2020 1. Karl Redl, "Phytochemische und Pharmakologische Untersuchungen von Bidens campylotheca Schultz Bip. ssp.

campylotheca und anderen polyacetylenhaltigen Arzneipflanzen", München 1992. 2. Andrea Pröbstle, "Phytochemische und pharmakologische Untersuchungen mit Houttuynia cordata, einer

entzündungshemmend wirksamen Arzneidroge der Traditionellen Chinesischen Medizin", München 1994. 3. Barbara Müller-Jakic, "Phytochemische und pharmakologische Untersuchungen von Zanthoxy-lum armatum DC.

und Zanthoxylum chalybeum Engl., sowie Untersuchungen zur Beeinflussung der Prostaglandin- und Leukotrienbiosynthese durch pflanzliche Inhaltsstoffe", München 1995.

4. Liu Yong, "Phytochemische und pharmakologische Untersuchungen von Lysionotus pauciflorus Maxim. und

Lycopus lucidus Turcz.", München 1996. 5. Sibylle Zschocke, "Phytochemische und pharmakologische Untersuchungen von Notopterygium incisum Ting ex

H.T. Chang und Angelica sinensis (Oliv.) Diels. sowie verwandter antiinflammatorischer Arzneidrogen aus der Familie der Umbelliferae", Düsseldorf 15.1.1998.

6. Marion Resch, "Zur Inhaltsstofführung und antiphlogistischen Wirkung der Rhizome von Atractylodes lancea und

verwandter Arten“, Düsseldorf 8.1.1999. Ausgezeichnet mit dem Egon-Stahl-Preis der Society for Medicinal Plant Research 7. Jochen Stöhr, "Vergleichende phytochemische und pharmakologische Untersuchung chinesischer Pfefferarten,

sowie zu Inhaltsstoffen und der pharmakologischen Wirkung von Piper sarmentosum", Düsseldorf, 1.6.1999. 8. Eveline Reininger, "Vergleichende phytochemische und pharmakologische Untersuchungen zur Hemmung der

Prostaglandin-H-Synthase Isoenzyme mit Arzneidrogen der chinesischen Medizin, insbesondere Platycodi radix und Chaenomelis fructus", Düsseldorf, 26.1.2001.

9. Kerstin Paulus, "Untersuchungen zur Leukotrienbiosynthese-hemmenden Wirkung chinesischer Arzneidrogen,

insbesondere von Salviae miltiorrhizae radix", Düsseldorf, 8.7.2002. 10. Birgit Dietz, "Inhaltsstoffe von Echinacea atrorubens, sowie zur Wirkung und Bioverfügbarkeit von Alkamiden",

Düsseldorf, 9.7.2002. 11. Anne Schwarte, "Phytochemische und pharmakologische Untersuchungen der Wurzeln von Sophora flavescens,

unter besonderer Berücksichtigung ihrer Wirkung auf die Leukotrien- und Prostaglandinbiosynthese", Düsseldorf, 9.7.2002.

12. Stefan Kahl, “Zur Suche neuer Wirkstoffe mit Antitumorwirksamkeit in chinesischen Arzneipflanzen”, Graz,

18.3.2005 13. Karin Wölkart, “Über phytochemische und pharmakologische Untersuchungen von Echinacea angustifolia DC.

sowie klinische Studien und neue Erkenntnisse zu molekularen Wirkmechanismen”, Graz, 14.7.2005 Ausgezeichnet mit dem Egon-Stahl-Preis der Society for Medicinal Plant Research 14. Michael Adams, "Investigations on the active principles of Chinese herbs with anti-inflammatory,

antimycobacterial and anticancer activity", Graz 11.11.2005. 15. Mathilde Fischer, "Phytochemische und pharmakologische Untersuchungen chinesischer Arzneipflanzen unter

besonderer Berücksichtigung von Centipeda minima", Graz 18.8.2006.

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16. Chanai Noysang, „Pharmacological and phytochemical investigations of Thai medicinal plants”, Graz 19.8.2008 17. Sandra Gusenleitner, „Establishment of NF-kB1 and COX-2 Gene Expression Assays in THP-1 cells for Bioassay-

Guided Isolation of Anti-inflammatory Compounds from TCM Drugs and Identification of Active Compounds from Cinnamomum cassia”, Graz 7.11.2008

18. María Salomé Gachet Otá ez, „Screening of Ecuadorian Plants for Anti-protozoal Activity and Phytochemical

Investigation of Jacaranda glabra (Bignoniaceae) and Cupania cinerea (Sapindaceae)“, Graz 30.11.2009 19. Martina Blunder, “Phytochemische und pharmakologische Untersuchungen von Arzneipflanzen mit

antiinflammatorischer Wirkung” (Phytochemical and pharmacological investigations of medicinal plants with anti-inflammatory activity), Graz 28.01.2011

20. Nadine Kretschmer, “Phytochemical and pharmacological investigations on constituents of medicinal plants with

potential anti-cancer activity” (Phytochemische und pharmakologische Untersuchungen von Arzneipflanzen mit potentieller Antikrebs-Wirkung), Graz 04.04.2011

21. Elisabeth Feizlmayr, “Phytochemical and pharmacological investigations of Echinacea pallida (NUTT.) NUTT.

roots including new insights into the biological activity of polyacetylenes and polyenes” (Phytochemische und pharmakologische Untersuchungen von Echinacea pallida (NUTT.) NUTT. mit neuen Erkenntnissen zur biologischen Wirkung von Polyacetalenen und Polyenen), Graz 17.11.2011

22. Ute Widowitz, “Phytochemical profiling and evaluation of the pharmacological effects of the Chinese herbal

decoction Huang Lian Jie Du Tang” (Phytochemische Analyse und Evalierung der pharmakologischen Effekte der chinesischen Kräuterteemischung Huang Lian Jie Du Tang), Graz 19.01.2012

23. Susanne Wagner, “Bioassay-guided isolation of cytotoxic compounds from Chinese medicinal plants with special

focus on Periploca sepium and Caesalpinia sappan“ (Aktivitätsgerichtete Isolierung von zytotoxischen Inhaltsstoffen aus chinesischen Arzneipflanzen mit speziellem Fokus auf Periploca sepium und Caesalpinia sappan), Graz 14.11.2012

24. Antje Bodensieck, “Phytochemische und pharmakologische Untersuchungen der Arzneipflanze Petasites

hybridus sowie weiterer Petasites-Arten” (Phytochemical and pharmacological investigations into the medicinal plant Petasites hybridus as well as into other Petasites species), Graz 11.07.2013.

25. Nadine Otto, "Inhibition of pro-inflammatory mediators NF-kB1 and COX-2 by Chinese medicinal plants and

bioassay-guided fractionation of Semen Ziziphi spinosae" (Hemmung der pro-inflammatorischen Mediatoren NF-kB1 und COX-2 durch Chinesische Arzneipflanzen und aktivitätsgerichtete Fraktionierung von Semen Ziziphi spinosae), Graz 12.06.2014.

26. Sabine Ortmann, "Phytochemical and pharmacological investigations of the anti-inflammatory principles of

Lonicera species using a plant metabolomics approach" (Phytochemische und pharmacologische Untersuchungen der entzündungshemmenden Inhaltsstoffe von Lonicera-Arten unter Verwendung von Pflanzenmetabolomics), Graz 08.06.2015.

27. Stefanie Nikles, “Metabolic and pharmacological profiling of three classical TCM formulations used for chronic

inflammatory diseases with immune dysfunction”, Graz 30.11.2016 28. San-Po Pan, “Phytochemical and pharmacological studies of leaves of Epipremnum pinnatum with a special

focus on the inhibition of COX-2 and IL-8 expression”, Graz 17.3.2017 29. Triet Thanh Nguyen, “Phytochemical and biological investigations of Vietnamese medicinal plants with a special

focus on anti-cancer and anti-inflammatory activities”, Graz, 17. Januar 2019 30. Christin Durchschein, “Phytochemical investigations of Zicao species and pharmacological investigations of novel

shikonin derivatives on melanoma cells”, Graz, 25. Januar 2019

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31. Huyen Tran Thi, “Phytochemical and pharmacological investigations of Sphaeranthus africanus”, Graz 25. November 2019

32. Xuehong Nöst, “A metabolomics approach for the holistic investigation of two complex herbal TCM

formulations”, Graz, 23. März 2020 33. Timo Andreas Thumann, “Studies on the interaction of the herbal medicinal product STW 5 with human

intestinal microorganisms”, Graz, 25. Juni 2020 34. Muhammad Khalil-ur-Rehman, “Phytochemical and pharmacological investigations of Asian medicinal plants

with potential anticancer activity – Dischidia nummularia, Sauromatum venosum, Trillium govanianum and Barringtonia acutangular”, Graz, 7. September 2020

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Publications

Univ.-Prof. Dr. Dr. h.c. Rudolf Bauer as by 25.12.2020 A) Published and edited books 1. Echinacea - Ein Handbuch für Ärzte, Apotheker und andere Naturwissenschaftler, Bauer, R., Wagner, H.,

Wissenschaftliche Verlagsgesellschaft mbH Stuttgart (1990) 2. Phytomedicines of Europe - Chemistry and Biological Activity, ACS Symposium Series 691, Eds. L.D. Lawson and

R. Bauer, ACS Books (1998) 3. Pharmazeutische Biologie 2, Arzneidrogen und ihre Inhaltsstoffe, 6. Auflage, H. Wagner unter Mitarbeit von R.

Bauer, Wissenschaftliche Verlagsgesellschaft mbH Stuttgart (1999) 4. Die Mistel in der Tumortherapie - Grundlagenforschung und Klinik, R. Scheer, R. Bauer, H. Becker, P. Berg, V.

Fintelmann (Eds.), KVC Verlag Essen (2001) 5. Fortschritte in der Misteltherapie, R. Scheer, R. Bauer, H. Becker, V. Fintelmann, F.H. Kemper, H. Schilcher (Eds.),

KVC Verlag Essen (2005) 6. Chinese Drug Monographs and Analysis (Eds. H. Wagner und R. Bauer), Verlag für Ganzheitliche Medizin Dr.

Erich Wühr GmbH, Kötzting (1996 - 2009) 7. Chromatographic Fingerprint Analysis of Herbal Medicines - Thin-layer and High Performance Liquid

Chromatography of Chinese Drugs; Vol. 1, 2, 3 & 4; H. Wagner, R. Bauer, D. Melchart, P.-G. Xiao, A. Staudinger (Eds.), Springer-Verlag, Wien (2016)

B) Patents 1. Wagner, Hildebert; Bauer, Rudolf; Ott, Holger

Isolation of sesquiterpene derivatives and pharmaceuticals containing thses compounds. Ger. Offen. (1987), 8 pp. CODEN: GWXXBX DE 3522075 A1 19870102 2. Bauer, Rudolf; Wagner, Hildebert. Tartrate-containing Echinacea extracts as immunostimulants. Ger. Offen. (1989), 6 pp. CODEN: GWXXBX DE 3744570 A1 19890713 3. Bauer, Rudolf; Wagner, Hildebert.

Immunostimulant Echinacea extracts containing carboxylic acid isobutylamides, oxoalkenes and oxoalkynes. Ger. Offen. (1989), 10 pp. CODEN: GWXXBX DE 3744571 A1 19890713 4. Wagner, Hildebert; Bauer, Rudolf; Ott, Holger.

Isolation of sesquiterpene esters from Parthenium integrifolium as immunomodulators. Ger. Offen. (1988), 10 pp. CODEN: GWXXBX DE 3638715 A1 19880526 5. Adams, Michael; Bauer, Rudolf; Bucar, Franz; Wube, Abraham Abebe: Pharmaceutical preparation for treating mycobacterial infections with 4-quinolines from Evodia rutaecarpa. PCT Int. Appl. (2006), 18pp. CODEN: PIXXD2 WO 2006094327 A1 20060914 6. BAUER, Rudolf; WENZIG, Eva-Maria; FRANZ, Chlodwig; STEFANON, Bruno; TZIKA, Eleni; KYRIAKIS, Spiros;

FARINACCI, Maura; SGORLON, Sandy Use larch wood material for treating inflammation. PCT Int. Appl. (2009), 35pp. PCT/AT2008/000473 WO/2009/079680 A1

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C) Published original and review papers 1. Bauer, R., Tittel, G., Wagner, H. HPLC-Nachweis und Isolierung von Phorbolestern aus Crotonöl - Eine neue Analysen-Methode für

Diterpenester in Euphorbiaceen Planta Medica 48, 10 - 16 (1983) 2. Bauer, R., Wagner, H. Cucurbitacinhaltige Drogen - Analyse und Standardisierung von Arzneidrogen und Phytopräparaten durch

HPLC und andere chromatographische Verfahren Dtsch. Apoth. Ztg. 123, 1313 - 1321 (1983) 3. Wagner, H., Schwarting, G., Varljen, J., Bauer, R., Hamdard, M.E., El-Faer, M.Z., Beal, J. Die chemische Zusammensetzung der Convolvulaceenharze IV - Die Glycosidsäuren von Ipomoea quamoclit,

I. lacunosa, I. pandurata und Convolvulus al-sirensis Planta Medica 49, 154 - 157 (1983) 4. Bauer, R., Berganza, L., Seligmann, O., Wagner, H. Cucurbitacins and Flavone C-Glykosides from Cayaponia tayuya Phytochemistry 24, 1587 - 1591 (1985) 5. Bauer, R., Khan, I.A., Wagner, H. Isolierung und Analyse neuer terpenoider Inhaltsstoffe aus Echinacea purpurea Acta Agron. Hung. 34, Suppl., 88 (1985) 6. Wagner, H., Reger, H., Bauer, R. Saponinhaltige Drogen und Fertigarzneimittel - HPLC-Analyse am Beispiel von Roßkastaniensamen Dtsch. Apoth. Ztg. 125, 1513 - 1518 (1985) 7. Bauer, R., Khan, I.A., Lotter, H., Wagner, H., Wray, V. Structure and Stereochemistry of New Sesquiterpene Esters from Echinacea purpurea (L.) MOENCH Helv. Chim. Acta 68, 2355 - 2358 (1985) 8. Antus, S., Bauer, R., Gottsegen, A., Seligmann, O., Wagner, H. Synthesis of Americanin-D Flavonoids and Bioflavonoids 31 - 38 (1985) 9. Bauer, R., Khan, I., Wagner, H. Neue Möglichkeiten zur Standardisierung von Echinacea-Extrakten Sci. Pharm. 54, 145 (1986) 10. Bauer, R., Khan, I., Wagner, H. Echinacea-Drogen - Standardisierung mittels HPLC und DC Dtsch. Apoth. Ztg. 126, 1065 - 1070 (1986) 11. Wagner, H., Wierer, M., Bauer, R. In vitro-Hemmung der Prostaglandin-Biosynthese durch etherische Öle und phenolische Verbindungen Planta Medica 52, 184 - 188 (1986) 12. Bauer, R., Khan, I.A., Wray, V., Wagner, H. Two Acetylenic Compounds from Echinacea pallida Roots Phytochemistry 26, 1198 - 1200 (1987) 13. Antus, S., Bauer, R., Gottsegen, A., Seligmann, O., Wagner, H. Synthese von Americanin-D Liebigs Ann. Chem. 357 - 360 (1987)

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14. Bauer, R., Wray, V., Wagner, H. The Chemical Discrimination of Echinacea angustifolia and Echinacea pallida Pharm. Weekbl. Sci. Ed. 9, 220 (1987) 15. Bauer, R., Khan, I.A., Wagner, H. Echinacea - Nachweis einer Verfälschung von Echinacea purpurea (L.) Moench mit Parthenium integrifolium

L. Dtsch. Apoth. Ztg. 127, 1325 - 1330 (1987) 16. Bauer, R., Wagner, H. Neue Ergebnisse zur Analytik von Echinacea Wurzeln Sci. Pharm. 55, 159 - 161 (1987) 17. Wagner, H., Jurcic, K., Bauer, R., Kreher, B. Immunologische In-vitro- und In-vivo-Untersuchungen von Arzneipräparaten Z. Phytother. 8, 180 - 183 (1987) 18. Bauer, R., Remiger, P., Wagner, H. Echinacea - Vergleichende DC- und HPLC-Analyse der Herba-Drogen von Echinacea purpurea, E. pallida und E.

angustifolia (3.Mitt.) Dtsch. Apoth. Ztg. 128, 174 - 180 (1988) 19. Bauer, R., Remiger, P., Wagner, H. New Alkamides from Echinacea angustifolia and Echinacea purpurea Roots Planta Medica 54, 563 - 564 (1988) 20. Dubois, M.-A., Bauer, R., Cagiotti, M.R., Wagner, H. Foetidissimoside A, A New 3,28-Bidesmosidic Triterpenoid Saponin, and Cucurbitacins from Cucurbita

foetidissima Phytochemistry 27, 881 - 885 (1988) 21. Bauer, R., Jurcic, K., Puhlmann, J., Wagner, H. Immunologische In-vivo- und In-vitro-Untersuchungen mit Echinacea-Extrakten Arzneim.-Forsch./Drug Res. 38(I), 276 - 281 (1988) 22. Bauer, R., Remiger, P., Wagner, H. Alkamides from the Roots of Echinacea purpurea Phytochemistry 27, 2339 - 2342 (1988) 23. Bauer, R., Wagner, H. Echinacea - Der Sonnenhut - Stand der Forschung Z. Phytother. 9, 151 - 159 (1988) 24. Heubl, G.R., Bauer, R., Wagner, H. Morphologische und anatomische Studien an Echinacea purpurea, E. angustifolia, E. pallida und Parthenium

integrifolium Sci. Pharm. 56, 145 - 160 (1988) 25. Bauer, R., Khan, I.A., Wagner, H. TLC and HPLC Analysis of Echinacea pallida and E. angustifolia Roots Planta Medica 54, 426 - 430 (1988) 26. Bauer, R., Remiger, P., Wray, V., Wagner, H. A Germacrene Alcohol from Fresh Aerial Parts of Echinacea purpurea Planta Medica 54, 478 - 479 (1988) 27. Bauer, R., Wagner, H.

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Echinacea-Drogen - Who is who? Z. Phytother. 9, 191 - 192 (1988) 28. Bauer, R., Remiger, P., Jurcic, K., Wagner, H. Beeinflussung der Phagozytose-Aktivität durch Echinacea-Extrakte Z. Phytother. 10, 43 - 48 (1989) 29. Jurcic, K., Melchart, D., Holzmann, M., Martin, P., Bauer, R., Doenecke, A., Wagner, H. Zwei Probandenstudien zur Stimulierung der Granulozytenphagozytose durch Echinacea-Extrakt-haltige

Präparate Z. Phytother. 10, 67 - 70 (1989) 30. Bauer, R., Remiger, P., Wagner, H. Alkamides from the Roots of Echinacea angustifolia Phytochemistry 28, 505 - 508 (1989) 31. Bauer, R., Remiger, P. TLC and HPLC Analysis of Alkamides in Echinacea Drugs Planta Medica 55, 367 - 371 (1989) 32. Heubl, G.R., Bauer, R. Echinacea-Arten - Mikroskopische Merkmale zur Identifizierung der Wurzeldrogen sowie der Verfälschung mit

Parthenium integrifolium Dtsch. Apoth. Ztg. 129, 2497 - 2499 (1989) 33. Bauer, R., Remiger, P. Der Einsatz der HPLC bei der Standardisierung von Echinacea-Drogen Arch. Pharm. 322, 324 (1989) 34. Antus, S., Baitz-Gacs, E., Bauer, R., Gottsegen, A., Seligmann, O., Wagner, H. Regioselective Synthesis of 2- and 3-Aryl-1,4-benzodioxanes Liebigs Ann. Chem. 1147 - 1151 (1989) 35. Antus, S., Baitz-Gács, E., Bauer, R., Gottsegen, A., Seligmann, O., Wagner, H. Total Synthesis of Cedrusin and Its Methyl Ether Liebigs Ann. Chem. 495 - 497 (1990) 36. Bauer R., Remiger P., Alstat E. Alkamides and Caffeic Acid Derivatives form the Root of Echinacea tennesseensis Planta Medica 56, 533 - 534 (1990) 37. Antus, S., Bauer, R., Gottsegen, A., Wagner, H. Enantiomeric separation of racemic pterocarpans by high performance liquid chromatography on

(+)poly(triphenylmethyl methacrylate) coated silica gel J. Chromatography, 508, 212 - 216 (1990) 38. Vogel, H., Jatisatienr, A., Bauer, R. Zur quantitativen Bestimmung der Glykoalkaloide Solasonin und Solamargin und deren Verteilung in Blättern

von Solanum laciniatum Ait. Angew. Botanik 64, 393 - 400 (1990) 39. Stuppner, H., Huber, M., Bauer,R. Festphasenextraktion und Headspace-Technik zur Probenvorbereitung für die GC-Analyse des Ätherischen

Öles in Kamillenpräparaten Sci. Pharm. 59, 71 (1991) 40. Bauer, R., Wagner, H.

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Äußere Einflüsse auf den Flavonoidgehalt von Kamillenblüten Sci. Pharm. 59, 3 (1991) 41. Bauer, R., Mayrbäurl, I., Stuppner, H. Vergleichende Untersuchungen der hydrophilen Inhaltsstoffe von Kamillenpräparaten Sci. Pharm. 59, 2 (1991) 42. Bauer, R., Breu, W., Wagner, H., Weigand, W. Enantiomeric separation of racemic thiosulphinate esters by high-performance liquid chromatography J. Chromatogr. 541, 464 - 468 (1991) 43. Bauer, R., Wagner, H. Echinacea Species as Potential Immunostimulatory Drugs in: Economic and Medicinal Plant Research, Vol. V, 253 - 321, Academic Press London (1991) 44. Bauer, R. Neues zu Inhaltsstoffen und Wirkung von Echinacea-Drogen Österr. Apoth. Ztg. 35/36, 705 - 714 (1991) 45. Bauer, R., Foster, S. Analysis of Alkamides and Caffeic Acid Derivatives from Echinacea simulata and E. paradoxa Roots Planta Medica 57, 447 - 449 (1991) 46. Bauer, R., Redl, K., Davis, B. Phytochemical and Pharmacological Investigations of Bidens campylotheca Planta Medica 57, Suppl. 2, A 68 (1991) 47. Redl, K., Davis, B., Bauer, R. New Polyacetylene Glycosides from Bidens campylotheca Planta Medica 57, Suppl. 2, A 88 (1991) 48. Bauer, R. Echinacea-Drogen - Neue Ergebnisse zur Frage der Wirksubstanzen Der informierte Arzt - Gazette Médicale 463 - 470 (1992) 49. Bauer, R., Redl, K., Davis, B. Four polyacetylene glucosides from Bidens campylotheca Phytochemistry 31, 2035 - 2037 (1992) 50. Antus, S., Bauer, R., Gottsegen, Á., Lotter, H., Seligmann, O., Wagner, H. Enantiomeric separation of racemic isoflavanones and related compounds on (+)-poly(triphenylmethyl

methacrylate)-coated silica gel J. Chromatography 603, 133 - 137 (1992) 51. Bauer, R., Pröbstle, A. Aristolactams and a 4,5-Dioxoaporphine Derivative from Houttuynia cordata Planta Medica 58, 568 - 569 (1992) 52. Redl, K., Davis, B., Bauer, R. Chalcone Glycosides from Bidens campylotheca Phytochemistry 32, 218 - 220 (1993) 53. Bauer, R. Echinacea-Drogen - Neue Ergebnisse zur Frage der Wirksubstanzen Natur und Ganzheitsmedizin (6) 13 - 22 (1993)

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54. Stuppner, H., Huber, M., Bauer, R. Zur Analytik des Ätherischen Öles in Kamillenpräparaten - Headspace-Gaschromatographie Pharm. Ztg. Wiss. 138, 46 - 49 (1993) 55. Bauer, R., Czygan, F.-C., Franz, G., Ihrig, M., Nahrstedt, A., Sprecher, E. Qualitätsansprüche an rational anwendbare Phytopharmaka Dtsch. Apoth. Ztg. 133, 4105 - 4108 (1993) 56. Bauer, R. Neue Ergebnisse zur Frage der Wirksubstanzen von Echinacea-Drogen Der Deutsche Apotheker, 45, 289 - 298 (1993) 57. Bauer, R., Liersch, R. Echinacea In: Hagers Handbuch der Pharmazeutischen Praxis, R. Hänsel, K. Keller, H. Rimpler, G. Schneider (Hrsg.) Band 5,

Drogen E - O, S. 1 - 34, Springer Verlag, Berlin, Heidelberg, New York (1993) 58. Bauer, R. Echinacea - Eine Arzneidroge auf dem Weg zum rationalen Phytotherapeutikon Dtsch. Apoth. Ztg., 134, 94 - 103 (1994) 59. Melchart, D., Linde, K., Worku, F., Bauer, R., Wagner H. Immunmodulation mit Echinacea-haltigen Arzneimitteln - Eine kriterien-gestützte Analyse der vorliegenden

kontrollierten klinischen Studien Forschende Komplementärmedizin 1, 27 - 36 (1994) 60. Müller, B., Redl, K., Breu, W., Pröbstle, A., Greger, H., Bauer, R. In Vitro Inhibition of Cyclooxygenase and 5-Lipoxygenase by Alkamides from Echinacea and Achillea Species Planta Medica 60, 37 - 40 (1994) 61. Redl, K., Breu, W., Davis, B., Bauer, R. Antiinflammatory Active Polyacetylenes from Bidens campylotheca Planta Medica 60, 58 - 62 (1994) 62. Bauer, R. Echinacea-Präparate: Unterschiede, Wirkung, Anwendung Apotheker Journal 16, 12 - 21 (1994) 63. Bauer, R., Czygan, F.-C., Franz, G., Ihrig, M., Nahrstedt, A., Sprecher, E. Pharmazeutische Qualität, Standardisierung und Normierung von Phytopharmaka Z. Phytother. 15, 82 - 91 (1994) 64. Pröbstle, A., Neszmelyi, A., Jerkovich, G., Wagner, H. Bauer, R. Novel Pyridine and 1,4-Dihydropyridine Alkaloids from Houttuynia cordata Natural Products Letters 4, 235 - 240 (1994) 65. Bauer, R. Chinesische Arzneidrogen als Quelle neuer Arzneistoffe für die westliche Medizin Pharmazie in unserer Zeit 23, 291 - 300 (1994) 66. Antus, S., Bauer, R., Gottsegen, Á., Lotter, H., Wagner, H. About the Chiral Regognition Mechanism of (+)-Poly(triphenylmethyl methacrylate)-coated silica gel ACH - Models in Chemistry 131, 467 -473 (1994) 67. Melchart, D., Linde, K., Worku, F., Bauer, R., Wagner H. Immunmodulation with Echinacea - A systematic review of controlled clinical trials Phytomedicine 1 (3), 245 - 254 (1994)

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68. Panossian, A.G., Müller-Jakic, B. Bauer, R., Wagner H. Dose dependent reversal effects of plumbagin on metabolism of arachidonic acid in porcine

polymorphonuclear leukocytes Phytomedicine 1 (4), 291 - 298 (1995) 69. Bauer, R. Chinesische Arzneidrogen und ihr Potential für die westliche Medizin Pharm. Ztg. 140, 1929 - 1941 (1995) 70. Liu, Y., Seligmann, O., Wagner, H., Bauer, R. Paucifloside, a New Phenylpropanoid Glycoside from Lysionotus pauciflorus Natural Product Letters 7, 23 - 28 (1995) 71. Kuhnt, M., Pröbstle, A., Rimpler, H., Bauer, R., Heinrich, M. Biological and pharmacological activities and further constituents of Hyptis verticillata Planta Medica 61(3), 227 - 232 (1995) 72. Bauer, R. Analytik und Standardisierung von Echinacea-haltigen Phytopharmaka Pharmazie in unserer Zeit 24, 93 - 95 (1995) 73. Bauer, R., Tittel, G. Quality assessment of herbal preparations as a precondition of pharmacological and clinical studies Phytomedicine 2, 193 - 198 (1996) 74. Müller-Jakic, B., Greger, H., Vermes, B., Bauer, R. Cyclooxygenase and 5-lipoxygenase inhibitory activity of tetrahydrofurofuran lignans Flavonoids and Bioflavonoids 1995 (Eds. S. Antus, M. Gabor, K. Vetschera) pp. 149 - 156, Akademiai Kiado,

Budapest (1996) 75. Liu, Y., Wagner, H., Bauer, R. New flavon glycosides from Lysionotus pauciflorus Maxim. Flavonoids and Bioflavonoids 1995 (Eds. S. Antus, M. Gabor, K. Vetschera) pp. 339 - 343, Akademiai Kiado,

Budapest (1996) 76. Pröbstle, A., Lotter, H., Wagner-Redecker, W., Matthiesen, U., Bauer, R. Cyclooxygenase inhibitory constituents from Houttuynia cordata Phytomedicine 2 (4), 305 - 308 (1996) 77. Bauer, R. Echinacea-Drogen - Wirkungen und Wirksubstanzen Z. ärztl. Fortbild. 90, 111 - 115 (1996) 78. Liu, Y., Wagner, H., Bauer, R. Nevadensin glycosides from Lysionotus pauciflorus Phytochemistry 42, 1203 - 1205 (1996) 79. Offermann, F., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Radix Bupleuri (Chaihu) Chinese Drug Monographs and Analysis, Vol. 1(1), 1996 80. Offermann, F., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Bulbus Fritillariae (Beimu) Chinese Drug Monographs and Analysis, Vol. 1(2), 1996

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81. Nenninger, A., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Radix Rehmanniae (Dihuang) Chinese Drug Monographs and Analysis, Vol. 1(3), 1996 82. Nenninger, A., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Fructus Schisandrae (Wuweizi) Chinese Drug Monographs and Analysis, Vol. 1(4), 1996 83. Bauer, R., S. Zschocke Medizinische Anwendung von Ginkgo biloba L. - Geschichtliche Entwicklung Z. Phytother. 17, 275-283 (1996) 84. Zschocke, S., Lehner, M., Bauer, R. 5-Lipoxygenase and Cyclooxygenase Inhibitory Constituents from Qianghuo (Notopterygium incisum) Planta Medica 63, 203-206 (1997) 85. Chrubasik, S., Enderlein, W., Bauer, R., Grabner, W. Evidence for antirheumatic effectiveness of Herba Urticae dioicae in acute arthritis: A pilot study Phytomedicine 4, 105-108 (1997) 86. Resch, M., Steigel, A., Bauer, R. Diacetoxy-substituted polyacetylenes from Atractylodes lancea Phytochemistry, 46(6), 1023-1028 (1997) 87. Bauer, R., Holz, A., Chrubasik, S., Kaffeoyläpfelsäure als Leitsubstanz in Brennesselzubereitungen in: S. Chrubasik und M. Wink (Hrsg.), Rheumatherapie mit Phytopharmaka, S. 112-120, Hippokrates Verlag

(1997) 88. Bauer, R. Echinacea - Pharmazeutische Qualität und therapeutischer Wert Z. Phytother. 18, 207-214 (1997) 89. Bauer, R. Standardisierung von Echinacea purpurea-Preßsaft auf Cichoriensäure und Alkamide Z. Phytother. 18, 270-276 (1997) 90. Roos, G., Waiblinger, J., Zschocke, S., Liu, J.H., Klaiber, I. Kraus, W., Bauer, R. Isolation, Identification and Screening for COX-1- and 5-LO-Inhibition of Coumarins from Angelica

archangelica Pharm. Pharmacol. Lett. 7, 157-160 (1997) 91. Seibt, A., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Herba Asari (Xixin) Chinese Drug Monographs and Analysis, Vol. 1(5), 1997 92. Pröbstle, A., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Herba Houttuyniae cordatae (Yuxingcao) Chinese Drug Monographs and Analysis, Vol. 1(6), 1997 93. Mayr, C., Wild, B., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Rhizoma Pinelliae (Banxia) Chinese Drug Monographs and Analysis, Vol. 1(7), 1997 94. Mayr, C., Michler, H., Wagner, H., Bauer, R., Xiao Peigen, Chen Jianming Radix Astragali (Huangqii) Chinese Drug Monographs and Analysis, Vol. 1(8), 1997

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95. Bauer, R. Quality criteria and standardization of phytopharmaceuticals: Can acceptable drug standards be achieved? Drug Information Journal 32, 101-110 (1998) 96. Bauer, R Echinacea - Biological Effects and Active Principles in: Phytomedicines of Europe - Chemistry and Biological Activity, ACS Symposium Series 691, Hrsg. L.D. Lawson

und R. Bauer, ACS Books (1998) 97. Resch, M., Steigel, A., Chen, Z.L., Bauer, R. 5-Lipoxygenase and cyclooxygenase inhibitory active compounds from Atractylodes lancea J. Nat. Prod. 61, 347-350 (1998) 98. Heilmann, J., Resch, M., Bauer, R. Antioxidant activity of constituents from Atractylodes lancea Pharm. Pharmacol. Lett. 8, 69-71 (1998) 99. Liu, Y., Wagner, H., Bauer, R. Phenylpropanoids and flavonoid glycosides from Lysionotus pauciflorus Phytochemistry 48, 339-343 (1998) 100. Bauer, R. Pflanzliche Immunstimulanzien in der Selbstmedikation Pharmazie in unserer Zeit 27, 144-157 (1998) 101. Liu, J.-H., Zschocke, S., Reininger, E., Bauer, R. Inhibitory effect of Radix Angelicae pubescentis on 5-lipoxygenase and cyclooxygenase Planta Medica 64, 525-529 (1998) 102. Bauer, R. The Echinacea Story - The Scientific Development of an Herbal Immunostimulant in: Plants for Food and Medicine - Modern Treatments and Traditional Remedies (Ed. H.D.V. Prendergast, N.L.

Etkin,, D.R. Harris, P.J. Houghton), S. 317 - 332, The Royal Botanic Gardens, Kew (1998) 103. Lobitz, G.O., Heilmann, J., Zschocke, S., Tamayo-Castillo, G., Bauer, R., Merfort, I. Bornyl cinnamate derivatives with anti-inflammatory activity from Verbesina turbacensis Pharm. Pharmacol. Lett. 8, 115-118 (1998) 104. Pietta, P., Mauri, P., Bauer, R. MEKC Analysis of Different Echinacea Species Planta Medica 64, 649-652 (1998) 105. Liu, J.-H., Zschocke, S., Bauer, R. A polyacetylenic acetate and a coumarin from Angelica pubescens f. biserrata Phytochemistry 49, 211-213 (1998) 106. Zschocke, S., Liu, J.-H., Stuppner, H., Bauer, R. Comparative Study of Roots from Angelica sinensis and Related Umbelliferous Drugs by Means of TLC, HPLC

and LC-MS Analysis Phytochemical Analysis 9, 283-290 (1998) 107. Liu, J.-H., Zschocke, S., Reininger, E., Bauer, R. Comparison of Radix Angelicae pubescentis and substitutes - Constituents and inhibitory effect on 5-

lipoxygenase and cyclooxygenase Pharmaceutical Biology 36, 207-216 (1998)

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108. Bauer, R., Zschocke, S. Angelika-Arten in außereuropäischen Ethnien Zeitschrift für Phytotherapie 19, 349-350 (1998) 109. Bucar, F., Resch, M., Bauer, R., Burits, M., Knauder, E., Schubert-Zsilavecz, M. 5-Methylflavasperone and rhamnetin from Guiera senegalensis and their antioxidative and 5-lipoxygenase

inhibitory activity Pharmazie 53, 875-878 (1998) 110. Tank, V., Mayr, C., Bauer, R. Über die Identität von „Mummy“, einer alten indischen Sakermedizin Greifvögel und Falknerei 1997, 116-118 (1998) 111. Bauer, R. Chemistry, analysis and immunological investigations of Echinacea phytopharmaceuticals. In: Immunomodulatory Agents from Plants (Ed. H. Wagner) Birkhäuser Verlag, Basel (1999) 112. Stöhr, J.R., Xiao, P.-G., Bauer, R. Isobutylamides and a New Methylbutylamide from Piper sarmentosum Planta Med. 65, 175-177 (1999) 113. E. Hahn-Deinstrop, R. Bauer Echinacea - Chromatographischer Nachweis einer Kreuzung von E. purpurea und E. angustifolia BIOforum 22, 109-114 (1999) 114. Bauer, R. 5-Lipoxygenase and cyclooxygenase as target for medicinal plant research in: Bioassay Methods in Natural Product Research and Drug Development (Eds. L. Bohlin, J.C. Bruhn), Kluwer

Acacemic Publishers, Dordrecht, Boston, London, (1999) 115. Melchart, D., Linde, K., Weidenhammer, W., Hager, S., Liao, J., Bauer, R., Wagner, H. Use of Traditional Drugs in a Hospital of Chinese Medicine in Germany Pharmacoepidemiology and Drug Safety 8, 115 - 120 (1999)

116. Heinrich, M., Koehler, I., Rimpler, H., Bauer, R. Bioactive compounds from the Mixe indian medicinal plant Peperomia pellucida Rev. Soc. Quim. Mex. 42, 245 - 248 (1999) 117. Bauer, R., Hoheisel, O., Stuhlfauth, I., Wolf, H. Preßsaft aus dem Kraut von Echinacea purpurea: ein allopathisches Phytoimmunstimulans Wiener Med. Wochenschr. 149, 185 - 189 (1999) 118. Melchart, D., Linde, K., Weidenhammer, W., Hager, S., Shaw, D., Bauer, R. Liver enzyme elevations in patients treated with traditional Chinese medicine JAMA 282 (1), 28-9 (1999) 119. Heilmann, J., Bauer, R., New medical applications of plant secondary metabolites In: Functions of Plant Secondary Metabolites and their exploitation in biotechnology. Annual Plant Reviews, Vol.

3 (Ed. M. Wink), pp. 274-310, Sheffield Academic Press, Sheffield (1999) 120. Bauer, R., Standardization of Echinacea purpurea Expressed Juice with Reference to Cichoric Acid and Alkamides J. Herbs, Spices & Med. Plants 6, 51-62 (1999)

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121. Wolf, H.-T., Zündorf, I., Winckler, Th., Bauer, R., Dingermann, Th. Characterization of Echinacea species and detection of possible adulterations by RAPD analysis Planta Med. 65, 773-774 (1999) 122. Liu, J.-H., Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Radix Angelicae pubescentis (Duhuo) Chinese Drug Monographs and Analysis, Vol. 2(9), 1999 123. Resch, M., Wagner, H., Bauer, R., Xiao P.G., Chen J.M. Rhizoma Atractylodis macrocephalae (Baizhu) Chinese Drug Monographs and Analysis, Vol. 2(10), 1999 124. Nenninger, A., Wagner, H., Bauer, R., Xiao P.G., Chen J.M. Rhizoma Belamcandae sinensis (Shegan) Chinese Drug Monographs and Analysis, Vol. 2(11), 1999 125. Liu Y., Wagner, H., Bauer, R., Xiao P.G., Chen J.M. Herba Lycopi lucidi (Zelan) Chinese Drug Monographs and Analysis, Vol. 2(12), 1999 126. Zschocke, S., Wagner, H., Bauer, R., Xiao P.G., Chen J.M. Rhizoma seu Radix Notopterygii (Qianghuo) Chinese Drug Monographs and Analysis, Vol. 2(13), 1999 127. Bauer, R., La ricerca nel campo dell´immunomodulazione

Erboristeria Domani Nov. 1999, 65-72 (1999) 128. Melchart, D., Linde, K., Hager, S., Käsmayr, J., Shaw, D., Bauer, R., Weidenhammer, W. Monitoring of liver enzymes in patients treated with traditional Chinese drugs Compl. Ther. Med. 7, 208-216 (1999) 129. Gaidi, G., Marouf, A., Hanquet, B., Bauer, R., Correia, M., Chauffert, B., Lacaille-Dubois, M.A. A New Major Triterpene Saponin from the Roots of Cucurbita foetidissima J. Nat. Prod. 63, 122-124 (2000) 130. von Raison, J., Heilmann, J., Merfort, I., Schmidt, T.J., Brock, F.E., Leven, W., Bomme, U., Bauer, R. Arnika - Arzneipflanze mit Tradition und Zukunft Z. Phytother. 21, 39-54 (2000) 131. Liu, J.-H., Steigel, A., Reininger, E., Bauer, R. Two New Prenylated 3-Benzoxepin Derivatives as Cyclooxygenase Inhibitors from Perilla frutescens var. acuta J. Nat. Prod. 63, 403-405 (2000) 132. Zschocke, S., Drewes, S.E., Paulus, K., Bauer, R., Van Staden, J. Analytical and pharmacological investigation of Ocotea bullata (black stinkwood) bark and leaves J. Ethnopharmacol. 71, 219-230 (2000) 133. Bauer, R. Anti-inflammatory herbal drugs: Pharmacological Aspects In: Herbal medicinal products for the treatment of pain. S. Chrubasik, B. Roufogalis, Eds., pp. 8-29, Southern

Cross University Press, Lismore 2000. 134. Bauer, R. Chemistry, Pharmacology and Clinical Applications of Echinacea Products In: Herbs, Botanicals and Teas. G. Mazza, B.D. Oomah, Eds., pp. 45-73, Technomic Publishing Company,

Lancaster, Basel 2000.

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135. Nüsslein, B., Kurzmann, M., Bauer, R. Kreis, W. Enzymatic Degradation of Cichoric Acid in Echinacea purpurea Preparations J. Nat. Prod. 63, 1615-1618 (2000) 136. Zschocke, S., van Staden, J., Paulus, K., Bauer, R., Horn, M.M., Munro, O.Q., Brown, N.J., Drewes, S.E. Stereostructure and anti-inflammatory activity of three diastereomers of ocobullenone from Ocotea bullata Phytochemistry 54(6), 591-595 (2000) 137. Bauer, R. Traditionelle Chinesische Medizin In: Arzneimittel der komplementären Medizin. J. Reichling, W.-D. Müller-Jahncke, A. Borchardt. S. 184-210, Govi-

Verlag, Eschborn 2001. 138. Franz, G., Bauer, R., Blaschek, W., Hamacher, H., Nahrstedt, A. Zukunftsperspektive für pflanzliche Extrakte Pharm. Ztg. 146, 488-494 (2001) 139. Dietz, B., Bauer, R. The constituents of Echinacea atrorubens roots and aerial parts Pharm. Biology. 39, 11-15 (2001) 140. Stöhr, J.R., Xiao P.G., Bauer, R. Constituents of Chinese Piper species and their inhibitory activity on prostaglandin and leukotriene

biosynthesis in vitro J. Ethnopharmacol. 75, 133-139 (2001) 141. Abourashed, E.A., Muhammad, I., Resch, M., Bauer, R., El-Feraly, F.S., Hufford, C.D.: Inhibitory Effects of Maesanin and Analogs on Arachidonic Acid Metabolizing Enzymes Planta Med. 67, 360-361 (2001) 142. Resch, M., Heilmann, J., Steigel, A., Bauer, R. Further phenols and polyacetylenes from the rhizomes of Atractylodes lancea and their anti-inflammatory

activity Planta Med. 67, 437-442 (2001) 143. Bauer, R., Netsch, M., Kreuter, M.H. Physiological function of phytopharmaceuticals and its utilization II - Echinacea purpurea (in Japanese) Food Processing and Ingredients 36, 58-62 (2001) 144. Zschocke, S., Claßen-Houben, D., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Radix Angelicae sinensis (Danggui) Chinese Drug Monographs and Analysis, Vol. 3(14), 2001 145. Zschocke, S., Claßen-Houben, D., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Radix Angelicae dahuricae (Baizhi) Chinese Drug Monographs and Analysis, Vol. 3(15), 2001 146. Zschocke, S., Claßen-Houben, D., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Radix Ligustici chuanxiong (Chuanxiong) Chinese Drug Monographs and Analysis, Vol. 3(16), 2001 147. Müller-Jakić, B., Claßen-Houben, D., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Pericarpium Zanthoxyli (Huajiao) Chinese Drug Monographs and Analysis, Vol. 3(17), 2001

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148. Dietz, B., Heilmann, J., Bauer, R. Absorption of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides after oral application of Echinacea

purpurea tincture Planta Med. 67, 863-864 (2001) 149. Goel, V., Chang, Ch., Slama, J.V., Barton, R., Bauer, R., Gahler, R., Basu, T.K. Alkylamides of Echinacea purpurea stimulate alveolar macrophage function in normal rats Int. Immunopharmacol. 2 (2-3) 381-387 (2002) 150. Aguilar JL, Rojas P, Marcelo A, Plaza A, Bauer R, Reininger E, Klaas CA, Merfort I. Anti-inflammatory activity of two different extracts of Uncaria tomentosa (Rubiaceae) J. Ethnopharmacol. 81(2), 271-276 (2002) 151. Jager H, Meinel L, Dietz B, Lapke C, Bauer R, Merkle HP, Heilmann J. Transport of Alkamides from Echinacea Species through Caco-2 Monolayers Planta Med. 68(5), 469-471(2002) 152. Bauer, R., Netsch, M., Kreuter, M.H. Physiological function of phytopharmaceuticals and its utilization XV - Stinging Nettle Root (in Japanese) Food Processing and Ingredients 37(3), 69-72 (2002) 153. Goel, V., Chang, Ch., Slama, J.V., Barton, R., Bauer, R., Gahler, R., Basu, T.K. Echinacea stimulates macrophage function in the lung and spleen of normal rats J. Nutr. Biochem. 13, 487–492 (2002) 154. Bauer, R. Neue Erkenntnisse zur Wirkung und zur Wirksamkeit von Echinacea purpurea-Preßsaftzubereitungen Wiener Med. Wochenschr. 152, 407 - 411 (2002) 155. Efferth T, Olbrich A, Bauer R. mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate,

arteether, and artemether Biochem. Pharmacol. 64(4) 617 - 623 (2002) 156. Ingolfsdottir K, Gudmundsdottir GF, Ogmundsdottir HM, Paulus K, Haraldsdottir S, Kristinsson H, Bauer R. Effects of tenuiorin and methyl orsellinate from the lichen Peltigera leucophlebia on 5-/15-lipoxygenases and

proliferation of malignant cell lines in vitro Phytomedicine 9(7), 654 - 658 (2002) 157. Grieblinger, E., Wagner, H., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Cortex Magnoliae officinalis (Houpo) Chinese Drug Monographs and Analysis, Vol. 4(18), 2003 158. Offermann, F., Grieblinger, E., Wagner, H., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Rhizoma Drynariae (Gusuibu) Chinese Drug Monographs and Analysis, Vol. 4(19), 2003 159. Michler, H., Bächer, S., Wagner, H., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Radix Puerariae (Gegen) Chinese Drug Monographs and Analysis, Vol. 4(20), 2003 160. Nörr, H., Bächer, S., Wagner, H., Bauer, R. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Radix Codonopis pilosulae (Dangshen) Chinese Drug Monographs and Analysis, Vol. 4(21), 2003

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161. Goel V, Lovlin R, Barton R, Lyon MR, Bauer R, Lee TD, Basu TK Efficacy of a standardized echinacea preparation (EchinilinTM) for the treatment of the common cold: a

randomized, double-blind, placebo-controlled trial. J Clin. Pharm. Ther. 29(1): 75-83 (2004) 162. Bauer, R. Das Potenzial von Arzneipflanzen zur Regulation des Lipidstoffwechsels und zur Arterioskleroseprophylaxe Phytotherapie 4(1), 17 - 20 (2004) 163. Wagner, H., Bauer, R. Grieblinger, E. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Fructus Gardeniae (Zhizi) Chinese Drug Monographs and Analysis, Vol. 5 (22), 2004 164. Wagner, H., Bauer, R. Grieblinger, E. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Rhizoma Gastrodiae (Tianma) Chinese Drug Monographs and Analysis, Vol. 5 (23), 2004 165. Wagner, H., Bauer, R. Grieblinger, E. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Herba Ecliptae (Mohanlian) Chinese Drug Monographs and Analysis, Vol. 5 (24), 2004 166. Wagner, H., Bauer, R. Bächer, S. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Herba Andrographitis (Chuanxinlian) Chinese Drug Monographs and Analysis, Vol. 5 (25), 2004 167. Wagner, H., Bauer, R. Bächer, S. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Radix Paeoniae albae/rubrae (Baishao/Chishao) Chinese Drug Monographs and Analysis, Vol. 5 (26), 2004 168. Wagner, H., Bauer, R. Bächer, S. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Flos Sophorae (Huaimi/Huaihua) Chinese Drug Monographs and Analysis, Vol. 5 (27), 2004 169. Wagner, H., Bauer, R. Grieblinger, E., Fischer, M. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M., Eds.) Rhizoma Coptidis (Huanglian) Chinese Drug Monographs and Analysis, Vol. 5 (28), 2004 170. Wagner, H., Bauer, R. Bächer, S. (Wagner, H., Bauer, R., Xiao P.G., Chen J.M.,( Eds.) Radix Stephaniae tetrandrae (Hanfangji) Chinese Drug Monographs and Analysis, Vol. 5 (29), 2004 171. Adams, M., Kunert, O., Haslinger, E., Bauer, R. Inhibition of leukotriene biosynthesis by quinolinone alkaloids from the fruits of Evodia rutaecarpa. Planta Medica 70, 904 - 908 (2004) 172. Schwaiger, S., Adams, M., Seger, C., Ellmerer, E.P., Bauer, R., Stuppner, H. Novel constituents of Leontopodium alpinum Cass. and their in vitro leukotriene biosynthesis inhibitory

activity. Planta Medica 70, 978 - 985 (2004) 173. Wagner, H., Bauer, R. Analytik von TCM-Drogen Dtsch. Apoth. Ztg. 144, 5007 - 5011 (2004) 174. Wölkart, K., Gangemi, J.D., Turner, R.B., Bauer, R. Enzymatic Degradation of Echinacoside and Cynarine in Echinacea angustifolia Root Preparations Pharm. Biology 42(6), 443 - 448 (2004)

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175. Cusan, C., Spalluto, G., Prato, M., Adams, M., Bodensieck, A., Bauer, R., Tubaro, A., Bernardi, P., Da Ros, T. Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and lipoxygenase (5-LOX) inhibitors

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277. Kretschmer N, Blunder M, Kunert O, Rechberger GN, Bauer R, Schuehly W. Cytotoxic Furanogermacranolides from the Flowers of Helianthus angustifolius. Planta Med. 77: 1912-1915 (2011)

278. Uzuner H, Bauer R, Fan TP, Guo DA, Dias A, El-Nezami H, Efferth T, Williamson EM, Heinrich M, Robinson N, Hylands PJ, Hendry BM, Cheng YC, Xu Q. Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities. J Ethnopharmacol. 140: 458-468 (2012)

279. Deeg, K.; Eichhorn, T.; Alexie, G.; Kretschmer, Nadine; Andersch, K.; Bauer, Rudolf; Efferth, T. Growth inhibition of human acute lymphoblastic CCRF-CEM leukemia cells by medicinal plants of the West-Canadian Gwich’in Native Americans. Natural Products and Bioprospecting 2: 35-40 (2012)

280. Kretschmer N, Rinner B, Deutsch AJ, Lohberger B, Knausz H, Kunert O, Blunder M, Boechzelt H, Schaider H, Bauer R. Naphthoquinones from Onosma paniculata Induce Cell-Cycle Arrest and Apoptosis in Melanoma Cells. J. Nat. Prod., 75(5): 865-869 (2012) DOI: 10.1021/np2006499

281. Wube A, Guzman JD, Hüfner A, Hochfellner C, Blunder M, Bauer R, Gibbons S, Bhakta S, Bucar F. Synthesis and Antibacterial Evaluation of a New Series of N-Alkyl-2-alkynyl/(E)-alkenyl-4-(1H)-quinolones. Molecules 17(7): 8217-40 (2012)

282. Gregori A, Kretschmer N, Wagner S, Boechzelt H, Klinar D, Bauer R, Pohleven F. Influence of Olive Oil Press Cakes on Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Berk.) Singer (Higher Basidiomycetes) Fruiting Bodies Production and Effect of their Crude Polysaccharides on CCRF-CEM Cell Proliferation. International Journal of Medicinal Mushrooms, 14(4): 419–424 (2012)

283. Kretschmer N, Rinner B, Stuendl N, Kaltenegger H, Wolf E, Kunert O, Boechzelt H, Leithner A, Bauer R, Lohberger B. Effect of Costunolide and Dehydrocostus Lactone on Cell Cycle, Apoptosis, and ABC Transporter Expression in Human Soft Tissue Sarcoma Cells. Planta Med. 78(16), 1749-1756 (2012)

284. Damianakos H, Kretschmer N, Sykłowska-Baranek K, Pietrosiuk A, Bauer R, Chinou I Antimicrobial and cytotoxic isohexenylnaphthazarins from Arnebia euchroma (Royle) Jonst. (Boraginaceae) callus and cell suspension culture. Molecules 17(12): 14310-22 (2012). doi: 10.3390/molecules171214310

285. Ip PS, Tsim KW, Chan K, Bauer R. Application of complementary and alternative medicine on neurodegenerative disorders: current status and

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286. Landa, P., Kutil, Z., Temml, V., Malik, J., Kokoska, L., Widowitz, U., Pribylova, M., Dvorakova, M., Marsik, P., Schuster, D., Bauer, R., Vanek, T. Inhibition of In Vitro Leukotriene B4 Biosynthesis in Human Neutrophil Granulocytes and Docking Studies of Natural Quinones. Natural Product Communications 8(1), 105-108 (2013)

287. Mahringer A, Ardjomand-Woelkart K, Bauer R, Fricker G, Efferth T. Alkamides from Echinacea angustifolia Interact with P-Glycoprotein of Primary Brain Capillary Endothelial Cells Isolated from Porcine Brain Blood Vessels. Planta Med. 79(3-4), 214 - 218 (2013)

288. Lohberger, B., Rinner, B., Stuendl, N., Kaltenegger, H., Steinecker-Frohnwieser, B., Rad, E.B., Weinberg, A.M., Leithner, A., Bauer, R., Kretschmer N., 2013. Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells. P L o S One 8,6 (2013)

289. Atanasov, A.G.; Blunder, Martina; Fakhrudin, N.; Liu, Xin; Noha, S.M.; Malainer, C.; Kramer, M.; Cocic, A.; Kunert, Olaf; Schinkovitz, Andreas; Heiss, E.H.; Schuster, D.; Dirsch, V.M.; Bauer, Rudolf Polyacetylenes from Notopterygium incisum–New Selective Partial Agonists of Peroxisome Proliferator-Activated Receptor-Gamma, P L o S One 4,8 (2013)

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292. Peter, K., Schinnerl, J., Felsinger, S., Brecker, L., Bauer, R., Breiteneder, H., Xu, R., Ma, Y. A novel concept of detoxification: Complexation between aconitine and liquiritin in a Chinese herbal formula (‘Sini Tang') J Ethnopharmacol. 149(2): 562-9 (2013)

293. Macková, A., Mučaji, P., Widowitz, U., Bauer, R. In vitro anti-inflammatory activity of Ligustrum vulgare extracts and their analytical characterization Nat. Prod. Commun. 8(11): 1509-1512 (2013)

294. Köberl M., Schmidt R., Ramadan EM., Bauer R., Berg G. The microbiome of medicinal plants: diversity and importance for plant growth, quality and health. Front Microbiol. 4, 400 (2013) .

295. Monschein M, Ardjomand-Woelkart K, Rieder J, Wolf I, Heydel B, Kunert O, Heuberger H, Bauer R. Accelerated sample preparation and formation of astragaloside IV in Astragali Radix Pharm Biol. 52(4): 403-409 (2014)

296. Bernaskova, M., Kretschmer, N., Schuehly, W., Huefner, A., Weis, R., Bauer, R. Synthesis of Tetrahydrohonokiol Derivates and Their Evaluation for Cytotoxic Activity against CCRF-CEM Leukemia, U251 Glioblastoma and HCT-116 Colon Cancer Cells Molecules 19, 1223-1237 (2014)

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297. Liu, JG, Peter, K., Shi, D.-Z., Zhang, L., Dong, G.-J., Zhang, D.-W., Breiteneder, H., Bauer, R., Jakowitsch, J., Ma, Y. Anti-inflammatory Effects of the Chinese Herbal Formula Sini Tang in Myocardial Infarction Rats Evidence-Based Complementary and Alternative Medicine, 2014, Article ID 309378, 10 pages (2014). doi:10.1155/2014/309378

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299. Schmidt R, Köberl M, Mostafa A, Ramadan EM, Monschein M, Jensen KB, Bauer R, Berg G Effects of bacterial inoculants on the indigenous microbiome and secondary metabolites of chamomile plants Front. Microbiol. 5:64 (2014) doi: 10.3389/fmicb.2014.00064

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302. Ardjomand-Woelkart, K., Bauer, R. Echinacea und seine Alkamide: Neue Erkenntnisse zur therapeutischen Wirksamkeit Deutsche Apotheker Zeitung, 154(4): 80-81 (2014)

303. Karsch-Völk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K

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304. Blunder, M., Kunert, O., Winkler, N.A., Schinkovitz, A., Schmiderer, C., Novak, J., Bauer, R.

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305. Pferschy-Wenzig, E.-M., Atanasov, A.G., Malainer, C., Noha, S.M., Kunert, O., Schuster, D., Heiss, E.H., Oberlies, N.H., Wagner, H., Bauer, R., Dirsch, V.M. Identification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gamma J. Nat. Prod. 77(4) 842 - 847 (2014)

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310. Noysang, C., Mahringer, A., Zeino, M., Saeed, M., Luanratana, O., Fricker, G., Bauer, R., Efferth, T. Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand Journal of Ethnopharmacology 155(1):633-41 (2014) DOI: 10.1016/j.jep.2014.06.001

311. Wang, L., Waltenberger, B., Pferschy-Wenzig, E.-M., Blunder, M., Liu, X., Malainer, C., Blazevic, T., Schwaiger, S., Rollinger, J.M., Heiss, E.H., Schuster, D., Kopp, B., Bauer, R., Stuppner, H., Dirsch, V.M., Atanasov, A.G. Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review Biochem. Pharmacol. In press (2014) DOI: 10.1016/j.bcp.2014.07.018

312. Wube, A.; Hüfner, A.; Seebacher, W.; Kaiser, M.; Brun, R.; Bauer, R.; Bucar, F. 1,2-Substituted 4-(1H)-Quinolones: Synthesis, Antimalarial and Antitrypanosomal Activities in Vitro Molecules 19(9), 14204-14220 (2014); doi:10.3390/molecules190914204

313. Peng L, Zou HQ, Bauer R, Liu Y, Tao O, Yan SR, Han Y, Li JH, Ren ZY, Yan YH Identification of Chinese Herbal Medicines from Zingiberaceae Family Using Feature Extraction and Cascade Classifier Based on Response Signals from E-Nose Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 963035, 7 pages, 2014. doi:10.1155/2014/963035

314. Zou HQ, Li S, Huang YH, Liu Y, Bauer R, Peng L, Tao O, Yan SR, Yan YH Rapid Identification of Asteraceae Plants with Improved RBF-ANN Classification Models Based on MOS Sensor E-Nose Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 425341, 6 pages, 2014. doi:10.1155/2014/425341

315. Galasso, S., Pacifico, S., Kretschmer, N., Pan, S.P., Marciano, S., Monaco, P., Bauer, R. Influence of seasonal variation on Thymus longicaulis C. Presl chemical composition and its antioxidant and anti-inflammatory properties Phytochemistry 107, 80-90 (2014). doi:10.1016/j.phytochem.2014.08.015

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317. Lohberger, B., Kretschmer, N., Bernhart, E., Rinner, B., Stuendl, N., Kaltenegger, H., Kahl, S., Bauer, R., Leithner,

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Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib

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319. Galasso, S., Piccolella, S., Kretschmer, N., Pan, S.P., Marciano, S., Bauer, R., Monaco, P. Seasonal variation in phenolic composition and antioxidant and anti-inflammatory activities of Calamintha nepeta (L.) Savi

Food Res. Int. 69: 121-132 (2015) DOI: 10.1016/j.foodres.2014.12.019 320. Leliebre-Lara V, Pferschy-Wenzig EM, Widowitz U, Ortmann S, Lima CN, Bauer R.

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322. Abdel Motaal, A., El-Askary, H., Crockett, S., Kunert, O., Sakr, B., Shaker, S., Grigore, A., Albulescu, R., Bauer, R.

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Inhibition of COX-2 and NF-kB1 Gene Expression, NO Production, 5-LOX, and COX-1 and COX-2 Enzymes by Extracts and Constituents of Onopordum acanthium

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327. Hummelsberger, J., Friedl, F., Gaus, W., Kohnen, R., Heuberger, H., Seidenberger, R., Aidelsburger, P., Bauer, R.,

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330. Zou, H.-Q., Lu, G., Liu, Y., Bauer, R., Tao, O., Gong, J.-T., Zhao, L.-Y., Li, J.-H., Ren, Z.-Y., Yan, Y.-H. Is it possible to rapidly and noninvasively identify different plants from Asteraceae using applying electronic nose with multiple mathematical algorithms?

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Novel Pharmaceutical Developments World J Tradit Chin Med 2(2): 1-23 (2016) 339. Lara V, Monzote Fidalgo L, Pferschy-Wenzig EM, Kunert O, Nogueiras Lima C, Bauer R. In Vitro Antileishmanial Activity of Sterols from Trametes versicolor (Bres. Rivarden) Molecules 21(8) pii: E1045 (2016) doi: 10.3390/molecules21081045. 340. Efferth T, Romero MR, Bilia AR, Osman AG, ElSohly M, Wink M, Bauer R, Khan I, Bergonzi MC, Marin Jose J.G. Expanding the Therapeutic Spectrum of Artemisinin: Activity Against Infectious Diseases Beyond Malaria and

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342. Blunder, M., Orthaber, A., Bauer, R., Bucar, F., Kunert, O. Efficient identification of flavones, flavanones and their glycosides in routine analysis via off-line combination

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Wrona, Rudolf Bauer Advancing Metabolic Profiling of Herbal Medicines with LC–HRMS LC-GC North America. 34(10): 10-17 (2017) 347. Nikzad-Langerodi R, Ortmann S, Pferschy-Wenzig EM, Bochkov V, Zhao YM, Miao JH, Saukel J, Ladurner A, Heiss

EH, Dirsch VM, Bauer R, Atanasov AG. Assessment of anti-inflammatory properties of extracts from Honeysuckle (Lonicera sp. L., Caprifoliaceae) by ATR-FTIR spectroscopy.

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Yuk, Giorgis Isaac, Rudolf Bauer Metabolic profiling of the traditional Chinese medicine formulation Yu Ping Feng San for the identification of constituents relevant for effects on expression of TNF-α, IFN-γ, IL-1β and IL-4 in U937 cells. J Pharm Biomed Anal. 145: 219-229 (2017). doi: 10.1016/j.jpba.2017.03.049

349. Wang, L., Palme, V., Schilcher, N., Ladurner, A., Heiss, E.H., Stangl, H., Bauer, R., Dirsch, V.M., Atanasov, A.G.

The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability Frontiers in Pharmacology 8, 596 (2017), DOI=10.3389/fphar.2017.00596

350. Liu X, Latkolik S, Atanasov AG, Kunert O, Pferschy-Wenzig EM, Heiss EH, Malainer C, Schinkovitz A, Kollroser M,

Dirsch VM, Bauer R. Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF-κB Inhibitors. Planta Med. 83(14-15): 1242-1250 (2017); doi: 10.1055/s-0043-118226.

351. Tzika, E. D., Tassis, P. D., Papatsiros, V. G., Pferschy-Wenzig, E. M., Siochu, A., Bauer, R., Alexopoulos, C., Kyriakis,

S.C., Franz, C. Evaluation of in-feed larch sawdust anti-inflammatory effect in sows Polish Journal of Veterinary Sciences, 20(2), 321-327 (2017). DOI: 10.1515/pjvs-2017-0039

352. Pferschy-Wenzig, E.M., Koskinen K., Moissl-Eichinger, C., Bauer R.

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