Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in...

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© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Transcript of Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in...

Page 1: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 2: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 3: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 4: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 5: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 6: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 7: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 8: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 9: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 10: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics

Page 11: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

© 1997 Nature Publishing Group http://www.nature.com/naturegenetics


Cleavage-Polyadenylation in the Immunoglobulin ,uL Gene

Cleavage-Polyadenylation in the Immunoglobulin ,uL Gene

Complete humanization of the mouse immunoglobulin loci ...

Complete humanization of the mouse immunoglobulin loci ...

IgTree©: Creating Immunoglobulin variable region gene lineage trees

IgTree©: Creating Immunoglobulin variable region gene lineage trees

Epitope specific antibody response is controlled by immunoglobulin VH polymorphisms

Epitope specific antibody response is controlled by immunoglobulin VH polymorphisms

Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim1

Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim1

HOXB1 founder mutation in humans recapitulates the phenotype of Hoxb1-/- mice

HOXB1 founder mutation in humans recapitulates the phenotype of Hoxb1-/- mice

A Single Immunoglobulin-like Domain of the Human Neural Cell Adhesion Molecule L1 Supports Adhesion by Multiple Vascular and Platelet Integrins

A Single Immunoglobulin-like Domain of the Human Neural Cell Adhesion Molecule L1 Supports Adhesion by Multiple Vascular and Platelet Integrins

Emergence of the immunoglobulin family: conservation in protein sequence and plasticity in gene organization

Emergence of the immunoglobulin family: conservation in protein sequence and plasticity in gene organization

peran immunoglobulin a dan lisozim dalam

peran immunoglobulin a dan lisozim dalam

A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis

A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus

Immunoglobulin class-switch recombination deficiencies

Immunoglobulin class-switch recombination deficiencies

Immunoglobulin: A Natural Way to Suppress Helicobacter pylori in Humans

Immunoglobulin: A Natural Way to Suppress Helicobacter pylori in Humans

Interactive Effects of Immunoglobulin Gamma and Human Leucocyte Antigen Genotypes on Response to Interferon Based Therapy of Hepatitis C Virus

Interactive Effects of Immunoglobulin Gamma and Human Leucocyte Antigen Genotypes on Response to Interferon Based Therapy of Hepatitis C Virus

Immunoglobulin Free Light Chains Are Increased in Hypersensitivity Pneumonitis and Idiopathic Pulmonary Fibrosis

Immunoglobulin Free Light Chains Are Increased in Hypersensitivity Pneumonitis and Idiopathic Pulmonary Fibrosis

Immunological Functions of Oxidized Human Immunoglobulin G in Type 1 Diabetes Mellitus: Its Potential Role in Diabetic Smokers as a Biomarker of Elevated Oxidative Stress

Immunological Functions of Oxidized Human Immunoglobulin G in Type 1 Diabetes Mellitus: Its Potential Role in Diabetic Smokers as a Biomarker of Elevated Oxidative Stress

Analysis of hybridoma mutants defective in synthesis of immunoglobulin M

Analysis of hybridoma mutants defective in synthesis of immunoglobulin M

Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation

Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation

Ligation of Macrophage Fcγ Receptors Recapitulates the Gene Expression Pattern of Vulnerable Human Carotid Plaques

Ligation of Macrophage Fcγ Receptors Recapitulates the Gene Expression Pattern of Vulnerable Human Carotid Plaques

Increasing intrathecal lymphocytosis and immunoglobulin G production in neurologically asymptomatic HIV-1 infection

Increasing intrathecal lymphocytosis and immunoglobulin G production in neurologically asymptomatic HIV-1 infection