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Programmes of theSchool of Life Sciences 生命科學學院課程•Biochemistry
•Biology
•Cell&MolecularBiology
•EnvironmentalScience
•FoodandNutritionalSciences
•MolecularBiotechnology
Faculty of Science | 理學院
Table of Contents
Message from the Director 01
Establishment of the School of Life Sciences 02
Why SLS at CUHK? 03
High Diversity in Life Sciences 04
CourseListfor4-yearCohort(2016-17)
StudyScheme
ExamplesofcoursepatternsfortheExplorationphase
World Class Education 11
Excellent Research 18
BreakingNews
AcademicHonoreesandAwardees
ResearchintheSchool
ResearchInstitutesandCenters
Ample Opportunities 31
Good Internationalization 34
Outstanding Career Prospects 35
Individual Programmes 40
Biochemistry
Biology
Cell&MolecularBiology
EnvironmentalScience
Food&NutritionalSciences
MolecularBiotechnology
Minimum Admission Requirements 59
Contact 60
| SCHOOL OF LIFE SCIENCES
Establishment ofthe School of Life Sciences
–ProfessorWongKam-Bo
Year Event
1963 EstablishedDepartmentofBiology
1971 EstablishedDepartmentofBiochemistry
1994 EstablishedEnvironmentalScienceProgramme, jointlybyDepartmentsofBiochemistry,Biology,andChemistry
EstablishedFood&NutritionalSciencesProgramme,jointlyby DepartmentsofBiochemistryandBiology
1998 EstablishedMolecularBiotechnologyProgramme,jointlyby DepartmentsofBiochemistryandBiology
2008 EstablishedCell&MolecularBiologyProgramme
2009 LaunchedLifeSciencesBroad-basedAdmissionScheme
2010 EstablishedtheSchoolofLifeSciences
01
TheSchoolofLifeScienceswasestablished
in 2010 under the Faculty of Science by
merging theDepartmentsofBiochemistry
and Biology, which are among the oldest
departmentsinCUHK.OurSchoolofferssix
majorprogrammes:Biochemistry,Biology,
Cell & Molecular Biology, Environmental
Science, Food & Nutritional Science, and
Molecular Biotechnology, which have
trained over 8400 alumni over the years.
Our curriculum is designed to meet the
diverse interests of life science students.
The students will receive training in fundamental knowledge in life sciences in their junior
years,beforetheyspecializeintooneofthesixprogrammesintheirsenioryears.
In addition to quality teaching, we also strive for excellence in research. For example, two
researchprojects“PlantandAgriculturalBiotechnology”and“CentreforOrganelleBiogenesis
andFunction”ledbyourschoolhavebeenselectedbytheUniversityGrantsCommitteeasone
oftheAreas-of-ExcellenceinHongKong.Webelievethatthebestwaytotrainfuturegeneration
ofscientistsistoinspirethestudentsandgivethemtheopportunitiestotakepartincutting-
edgeresearchthemselves.Tothisend,wehavetheSMART(youngScientistMentorshipAnd
ResearchTraining)andDREAM(DedicatedResearchExchangeAndMentorship)programsto
allowmotivatedstudentstoengageinresearchinlocalandoverseaslaboratories.Toequipour
studentswithaglobalperspectiveandenhancetheirlearningexperienceinaworld-renowned
university,wehaveintroducedaBerkeleyBiosciencesStudyAbroad(BBSA)Programme,which
enablesourstudentstospendasemesterinUCBerkeley.
If you are interested in the science of living organisms - from the structure and function of
DNAandproteinstotheinteractionsamonglivingorganismsinanecosystem;frompreparing
a career in environmental protection, food technologists, or nutritionists to research and
development of biotechnological products - you will find our diverse courses and flexible
curriculumfityourinterests.
Message from the Director
| SCHOOL OF LIFE SCIENCES
Why SLS at CUHK?
HighdiversityinlifesciencesThe School provides highly diverse and sophisticated courses in life sciences. Study topics cover frombiomoleculestoecology.AndtheflexiblecurriculumofferedbytheSchoolalsofitstheneedsofindividualstudents.
WorldclasseducationTheextraordinaryreputationofourprogrammesandtheexcellentquality ineducationarecommendedandaffirmedbytheQualityAssuranceCounciloftheHongKongUniversityGrantsCommittee(UGC).
ExcellentresearchThe School has a marvelous team of teachers who are field-pioneers and outstanding researchers. Forinstance,ourplantbiotechnologyresearchisanAreaofExcellence,withtheestablishmentoftheState-key laboratoryofAgrobiotechnology.Withavarietyof thestate-of-the-artequipmentandourexcellentresearchpersonnel,weensurethatourresearchshallcontinuetoprosper.
AmpleopportunitiesWe provide incomparable undergraduate research opportunities, for instance DREAM and SMARTprogrammes,andthesechancesaresomethingdifficulttofindinotherinstitutes.Studentswillalsofindnumerousexchangeandinternshipopportunitiesthatthelearningexperiencewillnotbeconfinedtothetextbooks and classrooms. A newly introduced Berkeley Biosciences Study Abroad (BBSA) Programmeenables selected students to study in UC Berkeley for a term with subsidies. In addition, plentiful ofotheractivitiesalsohelp todevelop theall-roundcompetence.Numerousscholarshipsareprovided tooutstandingstudentsthroughoutthestudies.
HighinternationalizationOurprogrammesattractlocalandoverseasstudents.Thisenablesstudentstoappreciatedifferentcultures,honelanguageskillsandgrowasconfidentindividuals.
OutstandingcareerprospectsAccording to the recent career survey of our graduates, the distribution of the work type of therespondents is as follows: 45% in scientific/research work and medical & health service; 10% inadministration/management; 15% in business/commerce; 6% each in environmental science,mediaandteaching,therestinhotel/tourism,disciplinedservice,construction/architecture,humanresource/trainingandlogistics/shipping,etc.
High Diversity in Life Sciences
03
High Diversity in Life Sciences
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
TheSchoolofLifeSciencesofferssixprogrammesthatfocusonthestudyofanextensiverangeoftopicsinallaspectsoflifesciences.
Intotal,weprovideover130coursesattheundergraduatelevelforourstudents.Inadditiontothelecturecourses,morethan40%ofthecoursestheSchooloffersarelaboratoriescourses,workshops,student-orientedteachingcourses,independentstudymodules,andsupervisedresearchcourses.Thiswidevarietyofcourseformatandcoursecontentfacilitatestheestablishmentofthesolidknowledgefoundationinlifesciences,andfostersthedevelopmentofstudents’all-roundcompetence.
Course Code Course Title Unit(s)LSCI1000 BiochemistryofHealthandDisease 3LSCI1001 BasicConceptsinBiologicalSciences 3LSCI1002 IntroductiontoBiologicalSciences 3LSCI1003 LifeSciencesforEngineers 3LSCI2002 BasicLaboratoryTechniquesinLife 2 SciencesLSCI2003 ScientificConductandEthics 2LSCI3000 SyntheticBiologyWorkshop 2LSCI4000 LiteratureResearchinLifeSciences 3
Course Code Course Title Unit(s)BIOL2120 CellBiology 3BIOL2210 Ecology 3BIOL2213 EcologyLaboratory 1BIOL2313 GeneticsLaboratory 1BIOL2410 GeneralGenetics 2BIOL3012 BiodiversityLaboratoryI 2BIOL3022 BiodiversityLaboratoryII 2BIOL3310 HumanBiology 3BIOL3410 GeneralMicrobiology 3BIOL3413 MicrobiologyLaboratory 1BIOL3530 PlantPhysiology 3BIOL3560 BiologyofFungiandNon-VascularPlants 2BIOL3570 BiologyofVascularPlants 2BIOL3610 InvertebrateFormandFunction 2BIOL3620 VertebrateLife 2BIOL3630 AnimalPhysiology 3BIOL3710 MarineBiology 3BIOL4010 EvolutionaryBiology 3BIOL4012 FieldandEnvironmentalBiology 2BIOL4032 PhysiologicalInvestigations 2BIOL4120 DevelopmentalBiology 3BIOL4220 EnvironmentalBiotechnology 3BIOL4260 ConservationBiology 3BIOL4310 HumanGenetics 3BIOL4510 HongKongFloraandVegetation 3BIOL4901 SeniorExperimentalProjectI 2BIOL4902 SeniorExperimentalProjectII 2BIOL4903 SeniorExperimentalProjectIII 2BIOL4906 Internship 2BIOL4907 FieldStudy 2
Course Code Course Title Unit(s)FNSC2001 IntroductiontoFoodSci&Technology 2FNSC2002 NutritionforHealth 2FNSC3001 FoodSciLabI 2FNSC3002 NutritionalSciLabI 2FNSC3010 NutritionandHumanDevelopment 3FNSC3030 NutritionalBiochemistry 3FNSC3110 FoodChemistryandAnalysis 3FNSC3180 FoodMicrobiology 3FNSC4001 FoodSciLabII 2FNSC4002 NutritionalSciLabII 2FNSC4110 FoodTechnology 3FNSC4120 CommunityNutrition 3FNSC4150 IntroductiontoMedicalNutritionTherapy 3FNSC4160 NutritionPlanningandFoodPolicy 3FNSC4170 FoodProductDevelopmentandQuality 3 ControlFNSC4901 SeniorExperimentalProjectI 2FNSC4902 SeniorExperimentalProjectII 2FNSC4903 SeniorExperimentalProjectIII 2FNSC4906 Internship 2FNSC5130 HumanPhysiology 3FNSC5320 NutritionalPhysiology 3FNSC5430 FoodToxicologyandSafety 3
Course Code Course Title Unit(s)CMBI2200 LiteraturesurveyinCMBandScientific 2 CommunicationCMBI2500 ResearchInternship 2CMBI3010 CMBLaboratoryI 3CMBI3020 CMBLaboratoryII 3CMBI3030 CMBLaboratoryIII 1CMBI3040 CMBLaboratoryIV 1CMBI3100 MethodologyofCriticalThinkinginCMB 2CMBI3101 BiologyofModelOrganismsforCMB 3 ResearchCMBI3200 ProposalFormulationandCreative 2 ScientificWritinginCMBCMBI4001 ProteinTrafficking 1CMBI4002 ProteinFolding 1CMBI4003 SignalTransduction 1CMBI4101 CancerCellBiology 1CMBI4102 StemCellBiology 1CMBI4103 NeuronalCellBiology 1CMBI4201 GenomicsandTranscriptomics 1CMBI4202 Proteomics 1CMBI4203 Metabolomics 1CMBI4301 CurrentTopicsinCellBiology 1CMBI4302 CurrentTopicsinMolecularBiology 1CMBI4303 CurrentTopicsinBiotechniques 1CMBI4901 SeniorExperimentalProjectI 2CMBI4902 SeniorExperimentalProjectII 2CMBI4903 SeniorExperimentalProjectIII 2
Course Code Course Title Unit(s)ENSC2270 IntroductiontoEnvironmentalScience 3ENSC2515 EnvironmentalChemistry 3ENSC2517 EnvironmentalChemistryLaboratory 2ENSC3230 PrinciplesofEnvironmentalProtection 3 andPollutionControlENSC3415 EnvironmentalInstrumentationTechniques 3ENSC3417 EnvironmentalInstrumentationTechniques 2 LaboratoryENSC3520 EnvironmentalandBiochemicalToxicology3ENSC3820 EnvironmentalandBiochemicalToxicology 2 LaboratoryENSC4210 EnvironmentalPollutionandToxicology 3ENSC4240 EnvironmentalImpactAssessment 3ENSC4242 EnvironmentalImpactAssessmentLaboratory2ENSC4250 EnvironmentalHealth 3ENSC4310 MethodsinToxicologicalResearch 3ENSC4510 MethodsinToxicologicalResearchLaboratory 2ENSC4525 AdvancedEnvironmentalChemistry 3ENSC4535 ChemicalTreatmentProcesses 3ENSC4901 SeniorExperimentalProjectI 2ENSC4902 SeniorExperimentalProjectII 2ENSC4903 SeniorExperimentalProjectIII 2ENSC4906 Internship 2ENSC4907 FieldStudy 2
Course Code Course Title Unit(s)MBTE2000 IntroductiontoMolecularBiotechnology 2MBTE2010 DiversityofLife:Applicationsand 2 SustainabilityMBTE3000 BusinessandSocialAspectsof 3 BiotechnologyMBTE4033 MethodsinMolecularBiotechnology 2 LaboratoryIMBTE4034 MethodsinMolecularBiotechnology 2 LaboratoryIIMBTE4320 GeneticEngineering 3MBTE4510 PlantBiotechnology 3MBTE4520 AnimalBiotechnology 3MBTE4530 MicrobialBiotechnology 3MBTE4901 SeniorExperimentalProjectI 2MBTE4902 SeniorExperimentalProjectII 2MBTE4903 SeniorExperimentalProjectIII 2MBTE4906 Internship 2
Course List for 4-year Cohort (2016-17)Life Sciences Biology
Food and NutritionalCell and Molecular Biology
Enviromental Science
Molecular Biotechnology
Course Code Course Title Unit(s)BCHE2000 FrontiersinBiochemistry 2BCHE2030 FundamentalsofBiochemistry 3BCHE2070 ResearchInternship 2BCHE3030 MethodsinBiochemistry 3BCHE3040 ProteinsandEnzymes 3BCHE3050 MolecularBiology 2BCHE3070 RecombinantDNATechniques 1BCHE3080 BioenergeticsandMetabolism 3BCHE3090 Self-studyModulesinBiochemistry 2BCHE3650 MolecularBiologyandRecombinant 2 DNALaboratoryBCHE3730 AnalyticalBiochemistryLaboratory 2BCHE4030 ClinicalBiochemistry 3BCHE4040 AspectsofNeuroscience 3BCHE4060 BasicandAppliedImmunology 3BCHE4080 BiochemistryforForensicSciences 2BCHE4090 BiochemistryforSportandExercise 2BCHE4130 MolecularEndocrinology 3BCHE4760 ImmunologyandHaematologyLaboratory 2BCHE4830 MedicalBiochemistryLaboratory 2BCHE4901 SeniorExperimentalProjectI 2BCHE4902 SeniorExperimentalProjectII 2BCHE4903 SeniorExperimentalProjectIII 2
Biochemistry
05 06
| SCHOOL OF LIFE SCIENCES
Study SchemeStarting from 2012, students who wish to choose Biochemistry, Biology, Cell & Molecular Biology,EnvironmentalScience,Food&NutritionalSciences,andMolecularBiotechnologyastheirmajorsarefirstnecessarytoenroll intheScienceProgramme(JS4601).Then,theybegintheirfirstphaseofstudy,whichcomprises thefirst3 terms, tostrengthen thebasicknowledge ingeneralscience. InTerm1andTerm2,studentsarerecommendedtofinishtheFacultyPackagewhichsecuresawideexposuretorelateddisciplines.ThisPackageincludes2introductorycoursesinlifescienceandchemistry,plus1electivecourseinphysics,mathematicsorstatistics.Afterward,inTerm3, 3coursesonthefundamentalsofbiochemistryandbiologyarecompulsorytostudents.Thesecourseswellserveasthesolidfoundationsforthesubsequentspecializedmajorstudiesinlifescience.
Thenextphaseoftheundergraduatestudyhelpstounderstandinmoredetailofthe6majorprogrammesintheSchoolofLifeSciences.InTerm4,studentscanchooseclassesfrom14differentcoursesofferedby our programmes. To avoid possible overloading, students are recommended not to take more than13unitsofmajorcourses.Nonetheless,thislimitationcanalreadyaccommodatetherequirementsofupto3majorstoacquiretheirpreliminarysavors.Throughthisflexiblecourse-selectingscheme,studentscancomprehendtheirspecificinterestsinthediversefieldsinlifesciencesandformulatetheirbestfittingchoiceforthemajors.
a choose only ONE laboratory course from BIOL2213, BIOL2313 or BIOL3413 (offered in the second year) for the major requirement of BIO.
General Study Scheme for entrants from 3-3-4 curricular system
Term 1
Term2
Term3
Term4
Term5
Term6
Term7
Term8
with foundation courses in life sciences in Term 3:LSCI2002+BIOL2120 +BCHE2030
Build up fundamental knowledgewith Faculty Package in Terms 1 and 2
LSCI1002* + CHEM1280 or CHEM1070 + onecoursefromMaths,Physics,Statistics.
Confi rm your interestSelect preferred courses from a list of 14 offered by all 6 programmes
BCHE2000 BCHE3050 BCHE3070 BCHE3650 BIOL2210 BIOL2213 BIOL2313 BIOL2410 CMBI2200 ENSC2270 FNSC2001, 2002 FNSC3180 MBTE2000 MBTE2010
Foster to be a specialistEngage in the advanced and specialized study
posed by your Major program
* Students who do not have high school Biology should take LSCI1001 prior to LSCI1002.
BCHE2000
BCHE3050
BCHE3070
BCHE3650
BIOL2210
BIOL2213
BIOL2313
BIOL2410
CMBI2200
ENSC2270
FNSC2001
FNSC2002
FNSC3180
MBTE2000
MBTE2010
Course code Unit BCHE BIOL CMBI ENSC FNSC MBTE
2
2
1
2
3
1
1
2
2
3
2
2
3
2
2
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07
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Examples of course patterns for the Exploration phase� Example 1:Alancanneverresistthetemptationfromfood.Startingfromseveralyearsago,theissuesofmalachitegreenandnitrofuranresiduesfoundinfreshwaterfish,Sudandyesineggsaswellasmelamineindairyproductshadarousedhisawarenessinthescienceoffoodsafety.Hence,hedecidestomajorinFNSC.
� Example 2:Jacksonenjoysnatureandoutdooractivities.Wheneverhehasachance,hewouldgocampingordivingwith his friends. However, it frustrates him a lot lately as he can hardly find a nice local place for theactivities due to pollution or urbanization. He wonders if he can contribute something to preserve ourplanet.Therefore,hewantstofocusonthestudyofbiodiversityandenvironmentalscience.
� Example 3:JennyisinterestedinthestudyofDNAandproteins,andwishestofindoutmoreaboutBCHE,CMBI,andMBTEbeforeshemakesafinaldecisiononhermajor.
Suggested course pattern in second term for:
Example 1: Alan
Course Unit
BIOL2410 2
FNSC2002 2
FNSC3180 3
1majorelective 3
Example 2: Jackson
Course Unit
BIOL2210 3
BIOL2213 1
BIOL2410 2
ENSC2270 3
Example 3: Jenny
Course Unit
BCHE2000 2
BIOL2410 2
BIOL2313 1
CMBI2200 2
MBTE2000 2
Total: 10 Total: 9 Total: 9
Afterthesecondphaseofstudy,studentsshouldfinalizetheirdecisionsonmajorselectionaccordingtotheirinterests.Thereare 3occasionsonwhichstudentscandeclaretheirmajor:afteradmission,bytheendofthefirstyearandbytheendofthesecondyearofstudy.Dependingonthepre-definedacademicachievements,studentscandeclaretheirmajoronanyoneofthe3occasionswithinthefirst2yearsofstudy.
Aftermajordeclaration,inthefinalphasewhichisbasicallythelast4terms,studentstakecoursestofulfillthestudyrequirementposedbythespecificmajortograduate.
Condition
* Apply to FNSC only
BiologyOR
ChemistryOR
CombinedScience(withBiologyorChemistrycomponent)ORIntegratedScienceOR
TechnologyandLiving*(FoodScienceandTechnologyStrandonly)
Level 5 or above in HKDSE of
LSCI1002
C+ or above in
LSCI1002,LSCI2002,
BCHE2030AND
BIOL2120
Taken(NOT necessarily ALL PASSED)
Declaration occasion After admission End of Year 1 End of Year 2
09 10
SCHOOL OF LIFE SCIENCES |
The Hong Kong University Grants Committee (UGC) stated that the University‘provides high quality student learning experience that refl ects its mission and role statement, underpinned by good quality assurance systems’.
Thismerit,ofcourse, isnottheonlyaffirmation.HongKongEconomicJournalMonthlyrankedCUHKtobe the top among the other UGC-funded universities.The six major criteria included the percentage ofPhDholdersforacademicstaff,JUPASadmissionresults,teachingqualities,financialresources,qualityofgraduates,andresearchperformance.
Indeed,thefacultymembersfromtheSchoolofLifeScienceshavebeenrecognizedtobecommendablethatoverthelastfewyears,ourteachershavebeenreceivingvariousteachingawards.
Vice Chancellor’s Exemplary Teaching Award Exemplary Teaching Award in General Education
Year Awardees2002 ProfessorLeeSau-TuenSusanna2003 ProfessorGeWei2007 ProfessorGeWei2008 ProfessorLeungKwok-Nam2012 ProfessorKongSiu-Kai
Year Awardees2012 Dr.ChiuChi-Ming Lawrence
Teachers in the School of Life Sciences
Chan Michael Kenneth, PhD (UC Berkeley)Email:[email protected]
ResearchInterests:1.Proteincrystallography2.Chemicalbiology
Director
12
World Class Education
World Class Education
Chan Ho-Yin Edwin, PhD (Cantab)Director,M.Sc.ProgrammeinBiochemicalandBiomedicalSciencesEmail:[email protected]
ResearchInterests:1.Cellular,geneticandbiochemical
analysesofRNAandproteintoxicityinneurologicaldiseases
2.Humandiseasemodelling
Professors
Wong Kam-Bo, PhD (Cantab)Director,SchoolofLifeSciencesEmail:[email protected]
ResearchInterests:1.Structure-functionstudiesofproteins2.Structure-determinationofproteinsby NMRspectroscopyandX-raycrystallography3.Proteinengineeringanddesign4.Simulationandmodelingofproteins
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Au Wing-Ngor Shannon, PhD (HK)Email:[email protected]
ResearchInterests:1.Proteinpost-translational modification2.Macromolecularassembly
Chan King-Ming, PhD (Nfl d.)Director,EnvironmentalScienceProgrammeEmail:[email protected]
ResearchInterests:1.Aquatictoxicology2.Molecularendocrinology3.Marinebiotechnology4.Environmentalpolicy
Chan Ting-Fung Philos, PhD (Wash.)Email:[email protected]
ResearchInterests:RNAgenomicsandbioinformatics:1.Functionsandregulationsof non-codingRNAsinbiological processesanddiseases;2.Genotype-phenotyperelationships incomplexdiseasesortraits;3.Softwaredevelopmentforhigh-throughputdataanalysis;4.Applicationsinsyntheticbiology
Wong Po-Keung, PhD (UC Davis)AssociateDirector,EnvironmentalScienceProgrammeEmail:[email protected]
ResearchInterests:1.Environmentalbiotechnologyand
microbiology2.Environmentaltechnology3.Ecotoxicology
Zhang Jian-Hua, PhD (Lancaster)Email:[email protected]
ResearchInterests:1.Plantphysiologyandmolecular
biologyunderenvironmentalstresses2.Cropphysiologyandcropproduction
Jiang Liwen, PhD (S. Fraser)Director,CellandMolecularBiologyProgrammeDirector,CentreforCellandDevelopmentalBiologyEmail:[email protected]
ResearchInterests:1.Cellandmolecularbiology2.Proteintargetingandtrafficking3.Plantendocytosisandexocytosis4.Organelledynamicsandbiogenesis5.Plantbiotechnology
Kong Siu-Kai, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Developmentofbiosensors2.Erythropoiesisandapoptosis3.Mitochondriaasregulatorsof
celldeath4.Cancerbiochemistry
Lam Hon-Ming, PhD (Northwestern)Director,MolecularBiotechnologyProgrammeEmail:[email protected]
ResearchInterests:1.Genomicstudyofsoybean2.Identificationandcharacterization offunctionalgenestoimprove
abioticstresstoleranceanddiseaseresistanceinplants;
3.Manipulationofnitrogensink-sourcerelationshipinplants
Shaw Pang-Chui, PhD (Lond.)Director,BiochemistryProgrammeDirector,CentreforProteinScienceandCrystallographyEmail:[email protected]
ResearchInterests:1.Structure-functionstudiesofproteins2.AuthenticationandqualitycontrolofChinese
medicinalmaterial
Associate Professors
13 14
Chen Zhen-Yu, PhD (Mass.)DivisionHead,ResearchPostgraduateProgrammesEmail:[email protected]
ResearchInterests:1.Cholesterolmetabolismandheart
diseases2.Antioxidantsandfreeradicals3.Fattyacidsandhealth
Cheung Chi-Keung Peter, PhD (NSW)AssociateDirector,FoodandNutritionalSciencesProgrammeEmail:[email protected]
ResearchInterests:1.Structure-functionofcellwall
polysaccharides2.Bioactivesubstancesfrom
mushroomandediblefungi3.Chemicalpropertiesandbiological
functionsofdietaryfiberandprebiotics
4.Functionalfoodsandnutraceuticals
Chu Ka-Hou, PhD (MIT/WHOI)Director,BiologyProgrammeDirector,SimonF.S.LiMarineScienceLaboratoryEmail:[email protected]
ResearchInterests:1.Molecularmarinebiologyand
biotechnology2.Biologyofcrustaceans
Fong Wing-Ping, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Structureandfunctionofantiquitin2.Anti-tumoreffectsofnovel photosensitizersin photodynamictherapy3.RoleofmiR-200inovariancancer development
.Structure-functionstudiesofproteins
.AuthenticationandqualitycontrolofChinese
Chu Lee-Man, PhD (Liv.)Email:[email protected]
ResearchInterests:1.Industrial,restorationand
urbanecology2.Pollutionstudies
Chung Hau-Yin, PhD (Louisiana State)AssociateDirector,FoodandNutritionalSciencesProgrammeEmail:[email protected]
ResearchInterests:1.Foodflavorchemistry,analysis
andapplication2.Naturalproduct,safety,health
andapplication3.Foodevaluationandfoodproduct
development4.Soy-basedfermentedfoodandseafood
Guo Dian-Jing Diane,DS(ChineseAcad.ofSc.)Email:[email protected]
ResearchInterests:1.Genomicsandbioinformatics2.Systemsbiology3.Plantstressresponse4.Plantsecondarymetabolismand trichomefunction
Kang, Byung-ho, PhD (Wisconsin-Madison)Email:[email protected]
ResearchInterests:1.Plantcellbiology2.3Delectronmicroscopy
Kwan Kin-Ming, PhD (HK)Email:[email protected]
ResearchInterests:1.Geneticmanipulationbytransgenic
andgeneknockouttechnology2.Studyoforganogenesisand
tumorigensis3.Mammalianneuraldevelopment4.Stemcellresearch
Kang, Byung-ho, PhD (Wisconsin-Madison)
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Kwan Hoi-Shan, PhD (UC Davis)Email:[email protected]
ResearchInterests:1.Genomicsandfunctionalgenomics2.Foodsafetyandauthentication3.Microbiology,molecularbiology andbiotechnology4.MolecularanalysisofChinesemedicine andfood
Ang Put Jr., PhD (Br. Col.)Email:[email protected]
ResearchInterests:1.Coralandcoralreefbiology,ecology
andecophysiology2.Seaweedecology,ecophysiology,
phylogeographyandapplications3.Environmentalandfunctional
responsesofmarineecosystems
He Jun-Xian, DS (Lanzhou)Email:[email protected]
ResearchInterests:1.Plantdevelopmentandsignal
transduction2.Functionalgenomicsandsignaling
mechanismsofplantstressresistance3.Improvementofcropyieldand qualityusingmolecularbiotechnologies
Hui Ho-Lam Jerome, DPhil (Oxon)Email:[email protected]
ResearchInterests:1.Organismalbiology/Evodevo2.MicroRNAsinanimal developmentalbiologyandevolution3.Homeoboxgenesregulationand
evolutioninanimals4.Invertebratesendocrinology,
reproductionandbiotechnology5.Genomicsandtranscriptomics
Luo Haiwei, PhD (South Carolina)Email:[email protected]
ResearchInterests:1.Molecularevolutionofmarine
bacteriaandarchaea2.Microbialgenomics3.Ecologicalandevolutionarybioinformatics
Ngo Chi-Ki Jacky, PhD (UC San Diego)Email:[email protected]
ResearchInterests:1.Structure-functionstudiesof
proteinsregulatingpre-mRNAsplicing2.Therolesofsplicingkinasesin
variouscancersandviralinfections3.Molecularbasisofinteractions
betweenkinasesandtheirsubstrates4.Structure-functionstudiesofcancer-relatedproteases
Wong Wing-Tak, Jack, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Vascularandmetabolicbiology2.Stemcellbiology3.Cardiovascularregeneration
Zhong Silin Steven, PhD (Nottingham)Email:[email protected]
ResearchInterests:1.Geneticsandepi-geneticsinplant
development2.Therolesoftranscriptionfactorin
hormonesignaling3.Sequencingtechnologyand
computationalbiology
Zhuang Xiaohong, PhD (CUHK)Email:[email protected]
ResearchInterests:1.PlantCellandMolecularBiology2.AutophagosomeBiogenesisand
AutophagyFunctioninPlants3.MembraneandProteinTrafficking
inPlantCells
.Ecologicalandevolutionarybioinformatics
.Coralandcoralreefbiology,ecology
developmentalbiologyandevolution
mechanismsofplantstressresistance
Lau Kwok-Fai, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Molecularneuroscience2.Molecularpathogenesisof neurodegeneration
Lee Sau-Tuen Susanna, PhD (Cornell)Email:[email protected]
ResearchInterests:1.NuclearreceptorPPARinhealth
anddiseases2.Phytochemicalsastherapeutic
targetsofmetabolicdiseases3.Transgenicanimalsfordisease
models
Leung Lai-Kwok, PhD (KentuckyDirector,FoodandNutritionalSciencesProgrammeEmail:[email protected]
ResearchInterests:1.Toxicologyandpharmacologyof
foodchemicals
Ngai Sai-Ming, PhD (Alta.)Email:[email protected]
ResearchInterests:1.Bioinformaticsandproteomics2.Protein/peptidestructuraland functionalstudies3.Researchanddevelopmenton modernChinesemedicine
Tsang Suk-Ying, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Stemcellbiology2.Derivativesofhumanembryonic stemcellsfortherapeuticpurposes3.Ionchannelsandcardiovascular physiology
Chen Li-yuan, PhD (East Anglia)Email:[email protected]
ResearchInterests:1.PlantE3ligases2.Stemcellsexpressedproteins
inplants3.Planthormonesignalpathways
Koon Chun, Alex, PhD (Mass.)AssociateDirector,LaboratoryofDrosophilaResearchEmail:[email protected]
ResearchInterests:1.Synapticplasticity2.Neurodegenerativediseases3.Neurobiology4.Developemtalbiology
Lee Ming-Ming Marianne, PhD (Ohio State)Email:[email protected]
ResearchInterests:1.Protein2.Proteindelivery3.Chemicalbiology
Qin Jing, PhD (HKU)Email:[email protected]
ResearchInterests:1.Bioinformatics2.Integrativeomicsapproachesfor
generegulationstudies3.Generegulatorynetworks4.Marinegenomics5.Stemcellandcancermulti-omics
Research Assistant Professors
Research Professor
Research Associate Professor
Assistant Professors
proteinsregulatingpre-mRNAsplicing
Zhong Silin Steven, PhD (Nottingham)
15 16
.MolecularanalysisofChinesemedicine
AssociateDirector,Laboratoryof
| SCHOOL OF LIFE SCIENCES
Chow Cheung-Ming Cherry, PhD (Oxford)Email:[email protected]
ResearchInterests:1.Plantcellbiology2.Membranetrafficking3.Nitrogenmetabolisminplants
Lo Fai-Hang, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Molecularcellbiology2.Cancerresearch3.Naturalproductresearch4.Lifescienceresearchandeducation methodologies
Ngai Hung-Kui, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Proteinbiochemistry2.Scienceeducation
Pang Kok-Shuen Iris, PhD (Yale)Email:[email protected]
ResearchInterests:1.Immunology2.Immunedefenseagainstviruses3.Commensalbacteriaandmucosal
immunity
Siow Lam Nina, PhD (HKUST)Email:[email protected]
ResearchInterests:1.Molecularandcellularneuroscience2.Cellsignalingandgeneregulation
Yam Kwan-Mei, MPhil (CUHK)Email:[email protected]
ResearchInterests:1.Molecularbiology2.Endocrinology3.Popularsciencepromotion4.Learningandteachingmethodologies
Chu Kin-Kan Astley, MPhil (CUHK)Email:[email protected]
ResearchInterests:1.Chemicalandphysicalanalyses
offoodmaterials2.Foodprocessingtechnology3.Foodproductdevelopment4.Molecularmarkerforfood authentication
Chui Pui Yi, Apple, PhD (CUHK)Email:[email protected]
ResearchInterests:1.Reproductiveandlarvalecology
ofcorals2.Coralrecruitmentdynamics3.Restorationecologyofcoralreefs
Yip Pui-Sze Peggy, MPH(BenedictineUniversity),RegisteredDietitian(USA)Email:[email protected]
ResearchInterests:1.Nutritionpromotion2.Publichealthandcommunity nutrition
Lecturers
Assistant Lecturers
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ExcellentResearchExcellentResearch
Senior Lecturer
Chiu Chi-Ming Lawrence, PhD (HKU)Email:[email protected]
ResearchInterests:1.Cellsignalinginapoptosis2.Cancerchemopreventionand chemotherapywithnatural
productstargetingthemolecularpathwaysincarcinogenesis
3.Applicationsofflowcytometry
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Hope for Patients withSpinocerebellar AtaxiaSpinocerebellarataxias(SCAs)refertoagroupofgeneticdiseasesthatcauseprogressivedeteriorationof the nervous system, particularly the cerebellum (referred to as ‘small brain’), and are, at present,consideredtobeincurable.Sufferersgraduallylosethefinemotorfunctionsoftheirbodiesandhavedifficultymaintainingbalanceorcoordinatingdailymovements.
Breaking News
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Innovative Platform for Food Authentication
Supermarketsmislabeledoilfishfiletascodfishfilet.Storesclaimedwhelkpiecesasabaloneslides.‘Fraudulentsubstitutions’ishotinthecity.TheydamagetheconfidenceofbothlocalsandtouristsinfoodproductsinHongKong.
The Innovative and Technology Commission of the HongKong Government funded a HK$3 million project ‘First-StageDevelopmentofPlatformforAuthenticationofDriedSeafoodandTonicFoodProducts’.TheleaderoftheprojectisProfessorKwanHoiShan,DirectoroftheFoodResearchCentreatCUHK.Theprojectaimstodevelopadatabaseandplatformwithmorphologicaldataand DNA sequences of common dried seafood and tonic foodproducts in Hong Kong. This platform enables the government,
local industry, and testing laboratories to monitor food products withDNAsequencemarkers.ThesecondtargetoftheprojectistodeveloparapidDNA-baseddiagnostickit forspeciesauthentication.Laboratoriescan quickly distinguish genuine products from the fake ones with thedatabaseandthekit.
Withtheseefficientqualityassurancecontrols,mislabelingandfraudulentsubstitutioninthelocalmarketscanbecontrolled.Theprojectwillcontributetofoodsafetyandenhancethereputationofthelocalfoodmarket.
Professor Kwan received a Bronze Bauhinia Star (BBS) of 2012for his meritorious public and community service, particularly hiscontributiontopromotingfoodsafetyandqualityassurance.
Professor Edwin Chan and histeam, consisting of biochemists,bioinformaticians, cell biologists,chemical pathologist, medicalgeneticists, neurologists andradiologist, embarked on a cross-disciplinary study with the aim ofunveiling the underlying cause of afamilialformofSCAidentifiedinthelocal population. With a concertedexperimental and bioinformaticeffort,theresearchersfinallyconfinedthe SCA mutation to the coiled-coildomain containing 88C (CCDC88C)gene. Thisnewlydiscovered formofSCAhasbeenrecognizedas ‘SCA40’.Thisworkwaspublished inJournalofMedicalGenetics,aleadinginternationalpeer-reviewedjournalinhumangenetics,in2014.ThisisthefirsttimethatresearchersfromHongKonghaveidentifiedanovelgenemutationthatleadstoSCA.TheHumanGenomeOrganizationGeneNomenclatureCommittee,aninfluentialinternationalorganizationformedbyscientistswhostudyhumangenetics,recentlyapprovedtheuseof‘SCA40’todescribethisnewtypeofSCA.ThisimportantfindinghasputHongKongontheworldmapofSCAresearch,andalsoshednewlightonfindingtherapeuticdirections.
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New Way to Battle Stomach Ulcers and CancerHalfofthehumanpopulationcarriesHelicobacter pylori,theonlyknownbacteriumthatsurvivesintheextremeacidicenvironmentinsidethestomach.Thisbacteriumdamagesthemucouscoatingofthegutafterwhichthestomachacideatsawaythesensitiveorgan lining resulting in peptic ulcers. The infection by thisbacterium is also well documented to be a high risk factor ofstomach cancer. Despite the effective mean with high efficacyof using antibiotics to battle with this bacterium, claims ofantibiotic-resistanceovertheyearshaveurgedthedevelopmentfornewtherapies.
‘Thekey to thesurvivalofHelicobacter pylori in theacidicbath in thehumanstomach is itsuseofanenzymecalledurease toneutralizegastricacid’, saidProfessorWongKam-Boof theCentre forProteinScience and Crystallography, School of Life Sciences. Urease requires two nickel ions to be functional.ProfessorWongandhisresearchteamdiscoveredthat,usingX-raycrystallographytovisualizeproteinswithatomicresolution,theassemblyoftheureasewiththenickelionsinvolvesfourhelperproteins:UreE,UreF,UreGandUreH.Theyfurtherrevealedthatdisruptingtheformationofthehelperproteincomplexforbidsthechannelingofthetwonickelionsinplaceandthusinhibitsthesynthesisoftheactiveureasethatisessentialtosurvival.
Theseconspicuousresultshavebeenreleasedlatelyas‘PaperoftheWeek’inJournalofBiologicalChemistry.ProfessorWongsaid,‘Withabetterunderstandingonhowthemolecularmachineisassembled,wecannowproceedtostudywaysthatdissembleit.AsactiveureaseisthekeytothesurvivalofHelicobacter pylori,newdrugsdesignedto target thiscomplexmaywellbeanovelandviablestrategy toeradicatethepathogen.’TheteamisnowdesigningdrugstoinhibitassemblyofthismolecularmachinethatkeepsHelicobacter pylorialiveinhumanstomach.
Breaking News
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The Story Inside and Behind the Soybean Genome
Genomic differences between wild and cultivated soybeans(Photo from Prof. Lam Hon-Ming)
Soybean,firstdomesticatedinChina,isthethirdmostimportantcashcropintheinternationaltrademarket. It istheNo.1sourceof vegetable protein, the leading source of edible oils as wellas a source of biodiesel. In addition, its high symbiotic nitrogenfixingcapacity isenvironmentally importantas itscultivationcannaturallyreplenishsoilnutrients.
Currently,morethantwo-thirdofthesoybeanconsumedinChinais imported. In2013, total importvalueofsoybeanbyChinahadrisentoarecordhighofUS$40billion,mostlyfromtheUSA,Braziland Argentina. However, due to the reduction of arable landsandfreshwaterresourcesinChinaandtheworld,theproductionof soybeans could not meet the its growing demand. Adverseenvironments like salinity also pose severe threat to agriculturalproductivity. Production of stress tolerant soybeans enables abetter use of marginal and low-fertility lands, and hence couldpromotesustainableagriculture.
Prof.LamHon-Ming,DirectoroftheCenterforSoybeanResearch(CSR),hasbeenworkingontheidentificationofstresstolerancegenesinsoybeanformorethan10years.In2010,Prof.LampublishedacoverarticleintherenownedscientificjournalNatureGenetics,reportingthedecodingof31wildandcultivatedsoybeangenomesthatrevealedamuchhigherbiodiversityinwildsoybeans.In2014,histeam has successfully identified and cloned a major salt tolerance gene fromwildsoybeans.ThisfindingwasrecentlypublishedinNatureCommunications,amulti-disciplinaryscientificjournalrankedjustafterNatureandScience.Itisamilestoneinthemassproductionofhighqualitysalttolerantsoybeans,astagereachedwhichwilleventuallybenefitagricultureinChinaandworldwide.
Prof.LamisnowworkingwithsoybeanbreedersinChinatoproducesalinityanddrought tolerantsoybeansthatcanbegrownonsalineand/orarid lands,vianon-GMmethods.Underhis leadership,CSRalsoholdsinternationalsoybeansymposium for researchers worldwide to facilitate international academicexchanges.
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FREE1: A Magic Plant Protein
Left to right: Cui, Gao, Jiang, Luo and Zeng.
Left to right: Gao, Jiang, and Zhuang.
Cellisthebasicunitoflife,whiletheorganellesinsidethecellaretheessential‘organs’oftheplant.Eachcellcontainsmanydifferentkindsoforganelles,whileorganelletypecomprisesdifferentproteinstoperformtheirspecificfunctionsthatcontroltheplantgrowthanddevelopment.
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iGEM – Gold Medal StorySyntheticbiology,arapidlyemergingfieldthatappliesabstractionand other important engineering concepts to biological science,has taken the undergraduate science and engineering educationby storm. The annual iGEM competition has quickly become themajorevent thatencouragesundergraduatestudentworldwide tospearheadinsyntheticbiologyresearch.
OuriGEMteamsconsistmainlybutnotlimitedtostudentsfromtheFacultyofScienceandEngineering.Weworktogetherusingsyntheticbiologyexperimentstodeveloptheir“bio-bricks”,thestandardizedDNApartstailor-madefordifferentspecifictasks,andcharacterizethemsystemicallyandscientifically,wealsoneedtoexplaintheirprojectstoothernon-sciencestudentsandrecentlytosecondaryschoolpupilsandthegeneralpublic.Since the iGEMgamesare internationalgames,weareable tomakecontactswith theirpeers fromuniversitiesoverseasviatheInternetandinthevirtualcompetitionduringtheiGEMJamborees.Thegamesalso
Professor Jiang’s research team has been workingon the underlying mechanisms of protein transport,organellebiogenesisand function inplantcells for15years at CUHK. They have recently discovered a newplant-specific protein (termed FREE1) playing multiplefunctional roles in regulating protein trafficking,organellebiogenesisandfunctioninplants.FREE1wasshownto1)Regulatethetraffickingofvacuolarproteins,2) Control the formation of intraluminal vesicles ofmultivesicular body (MVB), 3) Regulate the vacuolebiogenesis and 4) Mediate vacuole-autophagosomefusion and degradation during autophagy in plants.Since vacuole controls many important aspects ofcropphysiologyincludingseedgermination,pathogendefense,andgrowthundernutrient-limitingconditions,knowledge on the underlying mechanisms of vacuolebiogenesis and degradation will provide new tools forcropimprovementandplantbiotechnology.
These findings, shedding new light on the molecularmechanismsofproteintransport,organellebiogenesisand function in plants, have been published recentlyin two international journals: the Current Biology in2014andtheProceedingsof theNationalAcademyofSciences (PNAS) in 2015. Major contributors of thiswork include Drs. GAO Caiji, ZHUANG Xiaohong, CUIYong,LUOMingandMr.ZENGYunglin.
Previous iGEM projects of Hong Kong_CUHK and their achievements
Year Team Name Specifi c Project Achievements
2010 Bioencryption Using bacterial DNA to store encrypted World Jamboree Gold Medal information
2011 ChloriColight Using light-inducible halorhodopsin Gold Medal, best bio-brick, to transport chloride ion best bio-brick measurement, advanced to world jamboree
2012 Light of No Return Using light to attract bacteria to move by a Gold Medal, advanced to light-sensitive protein linked to a signaling world jamboree pathway to stimulate cell motility
2013 Switch off PAHs Using enzymes to degrade benzo-a-pyrene Silver Medal, advanced to or other polycyclic aromatic hydrocarbons world jamboree
2014 ABCDE, AzotoBacter Developed a protein expression system in Gold Medal obtained in vinelandaii Cluster- Azotobacter with genome recombination World Jamboree transformable Deoxygenated gene transfer cluster mechanism protein Expression
2015 Magnetosome Forming An expression system for the biosynthesis Gold Medal obtained in Azotobacter vinelandii of magnetosomes - prokaryotic intracellular World Jamboree organelles with magnetic properties - in Azotobacter for biotechnology applications
putemphasisonpresentationsinoralformat,posterformat,andtheuseofwikipages.
Joiningsuchcompetitioncouldprovideuswithopportunitiestobeatthefrontrowseattolearnthelatestdevelopmentof researchfieldandnewtechniquesoutsideof theclassroom.Most importantly,wealsolearnhowtoworktogetherandinteractwiththeirpeersattopuniversitiesaroundtheworld.Since2010,wehaveobtained4goldawards,1silveraward,andobtainedBestNewBio-BrickPart(Natural),BestBio-BrickMeasurementApproach,in2011AsiaJamboree(Table1).Ourteamshavehadmanyexposurestothegeneralpublicandmassmediathroughdifferentchannels.
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Academic Honorees and AwardeesAcademician of the Chinese Academy of Engineering and the International Eurasian Academy of Sciences
Professor SUN Sai-Ming SamuelProfessorSun is theResearchProfessorofBiology.He joined theUniversity in1995andwasChairoftheDepartmentofBiologyfrom1996to2004aswellastheFoundingDirector of the Molecular Biotechnology Programme from 1998 to 1999. He hasalso been the Director/Coordinator of the UGC-AoE Centre for Plant and AgriculturalBiotechnology(formerasPlantandFungalBiotechnologyCentre)since2000,Director
ofInstituteofPlantMolecularBiologyandAgriculturalBiotechnologysince2006,DirectorofStateKeyLabofAgrobiotechnology(CUHK)since2008,andMasterofS.H.HoCollegesince2009.
ProfessorSun’sresearchinterestsencompassanumberofareassuchasplantgeneisolation,characterization,transfer,expression,andregulation;plantbioreactors;aswellasricequality improvementandfunctionalgenomics.ProfessorSun iscreditedas thescientistwhofirstclonedaplantgene,discoveredplantgeneinterveningsequences,andenhancedanessentialaminoacidinplantthroughbiotechnologicalapproach.
Croucher Senior Research Fellowship
Professor JIANG LiwenDr.JiangjoinedCUHKBiologyasanAssistantProfessorin2000andwaspromotedasProfessorin2007.ProfessorJiangiscurrentlyChoh-MingLiProfessorofLifeSciencesofSchoolofLifeSciencesandDirectorofRGC-AoECentreforOrganelleBiogenesisandFunction,aswellasDirectorofCentreforCellandDevelopmentalBiology. Professor Jiang’s research team has been working on the underlyingmechanismsofprotein transport,organellebiogenesisand function inplantsfor15yearsatCUHK,andhasbeeninternationallyrecognizedasaleadinggroupinthefield.ProfessorJiangreceivednumerousawardsforteachingandresearchachievements,includingCUHKScienceFacultyExemplaryTeachingAward2008,CUHKResearchExcellenceAwardtwice(2006-07&2009-10),CroucherSenior Research Fellowship twice (2009-10 & 2015-16), Ministry of Education (MOE) Higher EducationOutstandingScientificResearchOutputAwardstwice(2009&2013),OutstandingFellowoftheFacultyofScience(2013)andChoh-MingLiProfessorshipofLifeSciences(2014).GraduatestudentsfromProfessorJiang’slabhavealsoreceivedmanyprestigiousawards,includingCUHKYoungScholarsDissertationAward(twice),PostgraduateResearchOutputAward(fourtimes),KeystoneSymposiumScholarship(twice)andHumanFrontierScienceProgramLong-TermFellows(twice).
As PI/PC, Professor Jiang has received competitive research grants worth over HK$70 million from theResearch Grants Council of Hong Kong, the Croucher Foundation and other important funding bodies.Professor Jiang has also served as editorial board member of several international journals, includingThe Plant Cell, Molecular Plant, BMC Plant Biology, Protoplasma, and Journal of Genetics and Genomics.
Breaking News
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Research Grant Council (RGC)-funded Collaborative Research Fund
Inthelastthreeyears,theSchoolofLifeSciencesreceivedboththeAoEandCRFfundingfromRGCtobuilduponourexistingstrengthsanddevelop them intoAreasofExcellence (AoE)and to fundprojectswithsignificantpotentialtodevelopintoanareaofstrength.
AoE Project:
Professor Liwen JiangandhisteamreceivedanAoEgrantofHK$47.25MtoestablishtheCenterofOrganelleBiogenesisandFunctionbeginninginJanuary2014.
CRF Project:
Professor Liwen JiangandhiscollaboratorswereawardedHK$7.36Mfor“EXPO(Exocyst-positiveOrganelle): Dynamics, Biogenesis and Functions in Plants”. Professor Jiang has just been awardedHK$8.36Mfor“EXPOandAutophagosomeinPlants”.
Professor Hon-Ming Lam and his collaborators were funded HK$6.99M for “Genomic andMolecularStudiesofaSalinityToleranceLocusintheWildSoybeanGenome”.
Professor Edwin Chan was granted HK$7M for his project titled “Targeting RNA and ProteinToxicitiesofPolyglutamineDiseasesUsingPeptidylicInhibitors”.
Professor KH ChuwasawardedHK$7.2Mforhisproject“MarineGenomics:CrustaceanEvolutionandAquaculture”
Other Research Awards
Research Excellence Award
CUHK Young Researcher Award
Year Awardees 2006-2007 ProfessorJiangLiwen 2007-2008 ProfessorChuKa-Hou 2008-2009 ProfessorChenZhen-Yu 2009-2010 ProfessorJiangLiwen 2012-2013 ProfessorLamHon-Ming
Year Awardees 2008-2009 ProfessorKwanKin-Ming 2009-2010 ProfessorChanHo-YinEdwin
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Research in the SchoolTheSchoolofLifeSciencesengagesactivelyinawidearrayofresearchareas.Theyvaryfromassmallasamoleculetoaslargeasahabitat.
Cell BiologyThiscoversawiderangeofinterdisciplinaryareasinlifesciencesthatexplainthemolecular and cellular organization, and how the signaling pathway regulatescellularfunction.Majortopicsincludesignaltransduction,cellfate,neuroscience,stemcellbiology,andcancercellbiology.
Molecular mechanisms of protein trafficking in the plant secretary andendocyticpathwaysprovidehintsforusingplantsasbioreactorsforproducingpharmaceuticals.
Recent development of stem cell research focuses on the basic biology andbiomedical application of embryonic stem cells that aim to identify possiblestrategiesforclinicaluses.
Cancer cells were discovered to be capable of recovering after exposure toa chemical cocktail that triggers programmed cell death. This finding couldpotentiallyhelpthedevelopmentofnew,moreeffectiveanti-cancerdrugs.
Neuroscience is the biology of nervous system, which allows us to sense and respond to the externalenvironment. Our neuroscience research actively investigates the pain hypersensitivity, neuronaldifferentiation,andthepathogenesisofnervoussystemdiseases,forinstance,Alzheimer’sandParkinson’sDiseases.
Ecology and Environmental ScienceOneofourresearchareasisinthedisciplineofwildlifeconservationandhabitatrestoration.Analysesofecosystemfunctioning,bioindicatorassemblages,andmicrobiologicalstatusarethekeyattributesofthedesirableecologicalchangesintermsoftheecosystemintegrityandhealth,whichareofprimaryconcernintheecologicalrestoration.Wealsoinvestigatevegetationcompositionandecologicalsuccessiononfly-ashlagoonsandusedmunicipallandfillsitesforbetterhabitatrestoration.
Enzymesfromfungiandmicroorganismsarestudiedforthebioremediationofsitespollutedbytoxicorganicmatters.Wealsostudythecontaminationsofmetalsandtraceorganicsinthecoastalareasandinlandwaters.
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Marine ScienceA number of nuclear protein-coding genes are used as DNA markersfor resolving the phylogenetic relationships among the decapodscrustaceanssuchasshrimps,lobstersandcrabs.
Thestudiesofdolphin,coralcommunities,andseaweedareunderwayinlocalmarineparks.Impactsofclimatechangeonmarineecosystemsarealsoofourconcerns.
Food & Nutritional SciencesNutritive food ingredients, like lipids and dietary fibers, and non-nutritivechemicals isolated from plant foods are investigated for their potentialbenefitsinpreventionofchronicdiseasedevelopment.
Thepalatabilityoffooddependsonoursensualperception.Keyfoodchemicalingredientsinteractingwithoursensoryreceptorareinvestigated.
Totacklediseasesthathavenotyetbeencuredbymodernmedicine,severalmembersintheSchoolareworkingonfunctionalfoodsandnutraceuticals.The neurological, anti-tumor, and immunomodulatory effects of the activecompoundsisolatedfromtraditionalChinesemedicinesandfunctionalfoodsareexaminedatgeneandproteinlevels,usingpathwayguided,genomicandproteomicapproaches.
Genomics & BioinformaticsThe Human Genome Project has brought enormoustechnological breakthroughs in sequencing technologythat give rise to a new area of research focusing onthe sequence, structural, and functional analysis ofthe genome of all living organisms. The importance ofgenomics isbestexemplifiedduringtheSARSoutbreakin 2003. CUHK researchers deciphered the SARS-coronavirus genome isolated from the patients, andinvestigatehowitmutatesfromthestaininpalmcivets.A number of professors in our School specialize indifferentaspectsofgenomicresearchsuchasevolution,population genetics and epigenetics, in a wide-rangeof living organisms with particular strengths in human,crustacean,andplantgenomics.
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Plant & Agricultural ScienceAchieved international excellence andobtained the official approval from TheMinistry of Science and Technology of P.R.China, SLS members established the State Key Laboratory (SKL) of Agrobiotechnology,in partnership with the prestigious ChinaAgricultural University in 2008. This SKL,comprised 16 principal investigators fromCUHK and 5 associate members from other
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ToxicologyTheresearchof toxicologyandhealthcentreson livermetabolismanddetoxificationenzymesofdrugsandenvironmentaltoxicants,chemicalcarcinogenesis,andthedevelopmentofbiomarkersofeffectsfromchemicaltoxicants.
Research Institutes and Centres�CentreofPlantMolecularBiologyandAgriculturalBiotechnology�CentreforCellandDevelopmentalBiology�CentreforProteinScienceandCrystallography�FoodResearchCentre�SimonFSLiMarineScienceLaboratory
Effects of environmental pollutants, such asmetals,pesticides,and traceorganicson livermetabolism of fish and rats are investigated.Sophisticated techniques involved in thetoxicology research include the differentialgene expression and proteomic studies,molecular toxicologicalapproachwith theuseofgenecloningandDNAarrayaswellastheuseof enzyme markers or reporter gene systemsfor the evaluations of potential health risksof the environmental contaminants includingendocrinedisruptors.Bothmammalianmodelsand fish models are being used for toxicityassessments.
NormalSlight deformity: curved backbone
Severe deformity: curved backbone and tail
Deformity observed in zebrafi sh larvae exposed to Brominated Diphenyl Ether (BDE)-47
Protein ScienceIn this post-genomic era, protein structure-function study is of majorimportance in understanding the molecular basis of cellular pathwaysand developing therapeutic targets. Our ongoing research projects focuson proteins in cellular signaling and biomedical science, pathogenicmicroorganisms,andareofbiotechnologicalsignificance.
Developmental BiologyHow can a single cell (fertilized egg) develop into amulticellular organism with specialized structures andorgans? This question also becomes a very importantmedicalquestion.
Anewbornmaypossesssometragicabnormalitywhentheembryodevelopmentgoeswrongasshowninthefiguresassomegenesaremutatedbygeneticengineeringtechnology.
Theknowledgeofnormaldevelopmentisthebaseforunderstandingabnormaldevelopmentaldiseases.
Thisareaofstudyismadepossiblebytheadvancedmolecularbiology,cellbiology,andgeneticengineeringtechnology.Themammalianembryonicdevelopmentalprocessisstudiedwithmouseasthemodelorganism.
The SKL team and the researchers from the member laboratories at the SKL 2014 Annual Meeting. The current director and deputy director are Prof. Jianhua Zhang and Prof. Hon-Ming Lam (front row, 7th and 9th from left, respectively).
localUniversities,hasreceivedasupporttotalled$19M(2011-2016)fromtheInnovationandTechnologyCommission.This national-level laboratory has a mission to up-scale China’s agricultural technology totheworldfrontierforincreasingagriculturalproductivity,safeguardingfoodsecurityinChina,improvingpeople’snutritionandpromotingcooperationbetweenChinaandHongKongonscientificadvancement.Prioritizedresearchareasincludethedevelopmentofstresstolerant,high-quantity,high-qualityandhighvalue-added crops via the application of state-of-the-art technologies such as genomics, proteomics,metabolomicsandrecombinantDNAapproaches.
SCHOOL OF LIFE SCIENCES || Life Science Programme
AmpleOpportunities
AmpleOpportunities
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SMARTThe new Young Scientist Mentorship And Research Training (SMART) Programme specifically offers adistinguishedresearchexperiencetofirstyearstudents.ThroughindividualguidancefromProfessorsinresearch laboratories, students are able to ignite their inquisitiveness in scientific research at the verybeginningoftheuniversityjourney.Besides,theymayalsoreceiveupto$3300asrewardsforworkingintheresearchlaboratory.
DREAMThe Dedicated Research Exchange And Mentorship (DREAM)Programmeprovidespreciousopportunitiesforourstudentstoexposetothefrontiersofbiologicalresearches.Ourstudentsfirstparticipateinacoachingprogramme,andlearnthebasictechniquesandbackgroundinformationrelatedtotheprojectfromalocalsupervisorintheSchool.During summer, as sponsored by the School, they travel abroad andconduct research projects in foreign laboratories or corporations.Participating institutions and corporations in 2015 include UniversityofCaliforniaatDavis,InstituteofMolecularBiology,AcademiaSinica,andtheLawOfficesofAlbertWai-KitChan,UniversityofTübingen,UniversityofCaliforniaofRiverside,UniversityofOklahoma,BrockUniversity,InstituteofBiologicalChemistryandBiodiversityResearchCenter,AcademiaSinica,etc.
Internship, Scholarship and other opportunities
BBSATheBerkeleyBiosciencesStudyAbroad(BBSA)ProgrammeisnewlyintroducedtoenableupperyearstudentsofourSchooltospendasemesterinUCBerkeley.Theycantake12unitsofupperlevelIntegrativeBiologyand Molecular & Cell Biology courses thereand the credits can be transferred back toCUHKtofulfilltheirgraduationrequirements.SelectedstudentswillbeawardedsubsidiesfortuitionfeeinUCBerkeley.
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University Student Sponsorship Programme
“ThankstotheUniversityandOceanParkConservationFoundation,wewenttoBohol,thePhilippinesfora10-daycetaceansurvey.Duringthe survey, the Pilipino cetacean experts led us to the sea alonga designated line transect. On the boat, three members took turneveryhourtoactivelysearchforthesignsofdolphinandwhalewithbinocular.During2-weeksurvey,wespottedcountlessdolphinsandwhales,rangingfromsmallFraser’sDolphintoenormousPilotWhale,and from active Spinner Dolphin to the shy Melon-headed Whales.Besides,10-meterWhaleShark,waterbirds,differentkindsoffishesand numerous marine organisms were also encountered. This tripbroughtustothenatureandtobeface-to-facewiththewildanimalsthatwecanneverexperienceandseeinHongKong!What’smore,itwasavaluablechanceforustoexperiencethethreathumanposedonourbelovedocean.Afterthistrip,wewoulddefinitelybemoreactivelyengagingourselvesintheconservationofourocean!”
2011participants–LamKa-YiuEric(ENSC)andLeGa-Wun(BIOL)
“It is really an unforgettable experience to participate in a birdpopulation research. Sponsored by Ocean Park ConservationFoundation,westayedinaforestofCebu,thePhilippinesfor14daystolookforanendemicendangeredbirdspeciesBlackShamaCopsychuscebuensis.These birds make long melodious call, and they are onlyfound in Cebu with a population of around 3000. During the 14-daystay,welearntbirdringingandradio-telemetry.Infact,whatwelearntmost was to appreciate the nature. A forest contains various typesofvegetation,and ishome fornumerousanimals. It isalways joyfulto live with the forest, the lovely animals and the stunning naturalenvironmentinharmony.”
2010participant–ChowMing-Him(ENSC)
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Good InternationalizationEveryyear,theUniversityattractsexcellentsecondarystudentsbothfromlocalandoverseas.Currently,theUniversityhascloseto2,000internationalstudentsfromcountriesandregions:allovertheworld.TheSchoolofLifeSciencesadmitted232studentsin2015/16.
SCHOOL OF LIFE SCIENCES |
Outstanding Career Prospects
Outstanding Career Prospects
ThediversetrainingbytheSchoolpreparesourgraduatestonotonlyfeatureinareasrelatedtotheirstudies,butalsofindtheirstarringpathsinareasoutsidelifesciences.
Interviews of Alumni
Biology programme at CUHK was my top choice for my undergraduate study. It offered a broadcurriculumaswellasspecialtopicsinlifesciencethatprovidedmeaverygoodfoundationformygraduatestudyinmarinebiologyaswellasthescientificknowledge,training,skillsof logicalandcriticalthinkingformycareerasaSeniorFisheriesOfficerinthegovernment.
1991Alumnus(Biology)-ChowWing-KuenSenior Marine Conservation Officer, Agriculture, Fisheries and Conservation Department of theGovernmentofHKSAR
I would like to say thanks to all my teachers for their guidance, support, and also the researchopportunitiessuchasthesummerresearchprogrammeandtheinternshipprogrammethatpromptedmetoapplytograduateschoolformoreintensegraduateresearchtraining.ThestudyatCUHKnotonlyprovidedmewithaplatformtoacquiretextbookknowledgeofbiochemistry,butmostimportantlyenabledmetoappreciateitsbeautyofthescientificknowledge.BeingaprofessoratCUHKnow,inadditiontofosteringresponsiblestudentsandresearchers,oneofmyanticipatedrolesistomakesurethattheknowledgeofbiochemistryandlifesciencescanreachdifferentstrataofoursociety,andultimatelyeveryonecanapplyscientificknowledgetotheirworkpositionsanddailylives.
1995Alumnus(Biochemistry)–ChanHo-YinEdwinProfessor,SchoolofLifeSciences,CUHKFacultyExemplaryTeachingAwardeeYoungResearcherAwardeeGeneticsSocietyofChinaThirteenthJu-ChiLiAnimalGeneticsPrizewinner
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To me, the program offered broad knowledge of fundamental science and ample opportunities totranslatewhatIhadlearntintopracticalresearchprojects. Interactivelabcourses,groupprojects,presentations, and diverse program activities are features of this program, which allowed us todevelopindependentthinking,teamwork,andeffectivecommunication.Ibelievetheprogramwillcontinuetothriveandfostertalentswhowillshineindifferentfields.
2002Alumna(MolecularBiotechnology)–LamHung-MingAssistantProfessor,UniversityofWashington,SeattleYoungInvestigatorAward,ProstateCancerFoundationCareerDevelopmentAward,PacificNorthwestProstateCancerSPORE,NCI/NIHIdeaDevelopmentAward(NewInvestigator),DepartmentofDefense’
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IamgladthatIchoseFNSCatCUHKasmyundergraduatemajor.Inadditiontothesolidknowledgeon food science and nutrition from the coursework, the soft skills, like trouble-shooting andcommunicationskills,creativity,andpassionbenefitedmycareerdevelopment.Thesummerlabandundergraduatefinalyearresearchprogrammearesomethinginparticulartomentionastheyallowedmetogainearlyexposuretofoodlaboratoryenvironment.
1997 Alumnus(FoodandNutritionalSciences)–LeungArnoldSeniorFoodScientist,theCoca-ColaCompany
Thoughthereisnodirectlinkagebetweenmymajorandmycurrentoccupation,themorein-depthknowledge in biological science, environmental science and geography help my understandingandanalysestowardsissuesrelatedtoenvironmentandlifescience.Thesedefinitelyfacilitatetheformulationofmorethoroughnewsreports.
2000Alumnus(EnvironmentalScience)–PunWai-LamSeniorReporter,TVB
Iamgladthatsome10yearsagoIputCUHKFoodandNutritionalSciencesprogrammeasmyfirstpriorityinmyJUPASform.Notmentioningitsmulti-disciplinarycurriculum(includingfoodscienceandtechnology,nutrition,biochemistry,biologyetc)providedmewithsolidscientificknowledge,theprogrammealsotrainedmewithavarietyofsoftskillsparticularlycriticalthinking,whicharestillveryusefulinmyeverydaywork.Inaddition,theprogrammeofferedalotofgreatlaboratoryresearchopportunities,especiallyfoodtechnologyandproductdevelopmentaswellasfinalyearproject,whichhelpedmetolearneffectivelyinapracticalandfunway!
2003Alumnus(FoodandNutritionalSciences)–MaKa-MingScientificOfficer,FoodandEnvironmentalHygieneDepartment,HKSARGovernment
Thecriticalpieceofmindacquiredfromprojectworkandassignmentwork,comprehensivethinkingand good communication/presentation skills obtained from lab report and project works, andpersistenceandapieceofmindtoservethecommunitylearntfromthefinalyearprojectaresomeof the critical generic skills that were trained by my major programme. These figured me into anenthusiasticterritoryeducatortoinspirestudentsinScienceEducationofthenextgeneration.Ibrokemyschool’s11yearsofrecordwiththehighestcreditratesandfullpassesformyclasses.SomeofmygraduateshavejoinedtheSchoolofLifeSciencesatCUHKintheseseveralyears.
2005Alumnus(Biology)–HoTikShunHead,DepartmentofScience,TheChineseFoundationSecondarySchool
WhenIenteredtheMBTprogrammein1998,Iwascompletelynewtothefieldofmolecularbiotechnology.Ithenprogressivelyacquiredstate-of-the-artmolecularbiotechnologyknowledgethroughamultitudeofways,includinglectures,sitevisits,summerinternship,aswellasbeingastudenthelperinthelaboratoryofwell-establishedscientists.Nowbeingateacherandmolecularvirologistmyself,Iamofferingthesesimilarwaystotrainandnurtureanewgenerationofourfuturescientists.Withoutdoubts,theMBTprogrammewillbeaperfectstageforthosewhoareseekingtodevelopandshineinthegoldenageofbiotechnology.
2001 Alumnus(MolecularBiotechnology)–ChanChi-WaiMartinResearchAssistantProfessorDepartmentofMicrobiology,TheChineseUniversityofHongKong
LookbackthetimewhenIchosemymajoratCUHK,Ibelievedthatfollowingmyownpersonalinterestswouldgiveno regrets tomy life,so Idevoted toScience,andMBTwasmyfirstchoiceas I reallyliketheideaofDNAandgenes.MBTprogramhasgivenmewonderfulUniversitylife,theProfessorsareinspiringandthelabcoursesarepractical,well-equippedmewithscientificknowledge,criticalthinking and laboratory techniques. Final year project has also trained me to be a careful, tough,logicalandoptimisticperson.Aftergraduation,IfurtherstudiedattheCUHKGraduateSchool,andwenttobothCanadaandUSAforaperiodofpost-doctraining.Luckily,nowIgotmyfacultypositionattheMacauUniversityofScienceandTechnology,andhavetheopportunitiestorunmyownlabandresearchprojects.Aftersomanyyears,IamstillveryproudofbeingthefirstyearofMBTgraduatesasithasstartedmyscientificcareerasaScientist,andIbelievedthatIhadmadethebestchoice.
2001 Alumna(MolecularBiotechnology)-LEUNGLaiHan,ElaineAssistantProfessorMacauInstituteforAppliedResearchinMedicineandHealthMacauUniversityofScienceandTechnology
ThecurriculuminFNSCatCUHKisnotonlybeneficialtomycareerbutalsomylife. Theseriesoffoodsafetyandmicrobiologycoursesbuiltupmyknowledge,preparedmewelltowinthejobasaHealthInspectorandgrantedmecompetitiveadvantageinmycareer.Ontheotherhand,thenutritionrelatedonesallowedmeto liveahealthier life though Iwasnot in thatfield.Not tomention, theinspiringandheartfeltwaysofteachingandinteractivelearningenabledmetoseeandthinkfromdifferentangles.AlsothankstotheFNSacademicvisitandexcursionprogramswhichhaveledmyeyesbeyondthelocalityandallowedmetoexchangetheexperiencewithcounterpartsoffoodandnutritionalsciencesinothercountries.
2006Alumnus(FoodandNutritionalSciences)–ChanYun-kwanHealthInspector,FoodandEnvironmentalHygieneDepartmentoftheGovernmentofHKSAR
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| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |39 40
Learninginterestingfactsaboutfoodandnutrition,doinglabs,cookingfornewfoodproducts–IwouldsaystudyingintheFNSprogrammewasoneofthemostenjoyabletimeinmylife.Ithasalsopavedthewayformycareerofbecomingaregistereddietitian.FNSteachingstaffweresupportiveandhelpedmemeetalltheessentialrequirementstoenrollintotheoverseasdieteticsmaster’sprogramme.TheknowledgeacquiredfromtheFNSprogrammewasusefulandpractical,whichenabledmetooftenexcelinthepostgraduatestudyofdietetics.OurFNSdietitianalumniwereveryhelpfultoobysharingtheirexperiencesinoverseasdieteticstudyandreal-lifeworkasalocaldietitian.Iwouldliketotakethisgoodopportunitytosay“thankyou”toyouall.
2006 Alumnus(FoodandNutritionalSciences)–WongSze-ManCandyDietitian,HospitalAuthorityMasterofScienceinNutritionandDietetics,theUniversityofSydneyAccreditedDietitian,HongKongDietitiansAssociationAccreditedPractisingDietitian,DietitiansAssociationofAustralia
Biochemistry
Biology
CellandMolecularBiology
Programmes in the School of Life Sciences
EnvironmentalScience
Food&NutritionalSciences
MolecularBiotechnology
Aftergraduation,Icontinuedmystudyinthefinanceareas,andobtainedmyMasterdegreeinFinanceandtheAdvancedDiplomainProfessionalFinancialPlanning.Iamnowworkingintheareaoffinancialplanningengaginginthewealthandrelationshipmanagement.Financialworldisfullofuncertainties.StrongandindependentlogicalthinkingandscientificmethodIacquiredfrommyundergraduatestudybenefitmyjudgmentindecipheringthereasonandfindingouttheanswersfortheseuncertainties.Iparticularlythanktheinspirationprovidedbymyprogrammeforthescientificandpersonalgrowth.
2007Alumnus(Biology)–MokKai-CheungStevenChiefWealthManagementAdvisor,ConvoyFinancialServicesLimitedSwissPrivilege–FinancialPlanningTop10AwardeeHongKongInstituteofBank–FinancialPlanningCompetitionAwardee
Theprogrammeequippedmewithknowledge,boththeoreticalandpractical,ofcurrentadvancesin the field and skills for conducting research in life sciences.These prepared me well for thestudyofM.Philthatfacilitatedmyjobhuntingintheeducationfieldaftergraduation.ThetrainingalsoallowsmetosharethecurrentdevelopmentinthefieldwithstudentsbothfromtheviewofresearchersaswellaspublichealthwhichishotinLiberalStudies.
2007 Alumnus(Biochemistry)–HoLilianGraduateMaster/Mistress,HolyTrinityCollege
SCHOOL OF LIFE SCIENCES |
BackgroundBiochemistry isabranchofsciencethat investigatesthechemicalcompoundsandprocessesoccurringinlivingorganismsatmolecularlevel.Theknowledgeprocuredfromthestudyinbiochemistryhasfoundextensiveapplicationsinmedicineandbiotechnologythatdrasticallyrevolutionizeourdailylife.
In1971,theUniversityestablishedtheDepartmentofBiochemistry(nowtheBiochemistryprogramme),anditquicklybecameastrongprogrammeinteachingandresearch.ThestudyofBiochemistryintheSchoolcomprisesabroadarrayofscientificdisciplines,includingthechemistryoflifeprocesses,bioinformatics,the metabolism of biomolecules and their regulation, energy transformation, the functions of enzymesandthestructure-functionrelationshipofenzymesandproteins,genomeresearchandgeneticdiseases,heredityandevolution,themechanismsofthenervous,immuneandendocrinesystems,biotechnology,andbiomedicalsciences.
Mission� Toprovideconceptsandmechanismsofbiochemicalprocesses,withemphasisonclinicalandbiomedical
sciences�Toprovidetrainingonthelatestbiochemicaltechnology�Tocultivatetheabilityofcriticalthinking,aproactiveandresponsibleattitudeandefficientcommunication
skillsforhighcompetitivenessinfurtherstudyandinthejobmarket
BIOCHEMISTRY
Curriculum Highlights�Currenttopicsinbiochemistryandmolecularbiologythathavescientific,medicalandsocialsignificance�Self-studymodulesandindependentresearchopportunity
Biochemistry (BCHE)
Study Focus: Elective Areas:� GeneticsandCellBiology � IndependentresearchinBiochemistry
� ProteinandEnzymes � Self-studymodulesinBiochemistry
� BioenergeticsandMetabolism � ClinicalBiochemistry
� MethodsinBiochemistryand � Immunology
MolecularBiology � Endocrinology
� BiomedicalandHealthSciences � Neuroscience
� IndependentResearch � ForensicSciences
� SportSciences
� AdvancedtopicsofferedbySLSprogrammes:
Biology: Microbiology,AnimalPhysiology,HumanGenetics
Cell & Molecular Biology:ProteinTraffickingandFolding,StemCellBiology, CellBiologyofCancerandNeuronalSystem
Environmental Science:BiochemicalToxicology,EnvironmentalHealth Food & Nutritional Sciences: MedicalNutritionTherapy,Nutritionand HumanDevelopment
Molecular Biotechnology:AnimalBiotechnology
� Statistics:Biostatistics
Curriculum
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Career Talks given by Alumni
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Expected learning outcomes
Views of current students
ContactWebsite:www.bch.cuhk.edu.hk/Email:[email protected]:852-3943-6359
ProgrammeDirector:[email protected]
BackgroundBiologyisabroadfieldembracingmanydifferentdisciplines,whichincludethestudyoflivingorganismsfromvirustohuman.Fundamentaltothestudyoflifeisunfoldingbiologicalorganizationatitsmanylevels,from molecular architecture to ecosystem structure. During the past few decades, new discoveries inbiologyhashavebroughtsignificantimpactonthewaywelive.Armedwithexcitingnewresearchmethodsandinformationfromgenomicsofhumanandotherlivingorganisms,biologistsarebeginningtounravelsomeoflife’smostengagingmysteries.
TheDepartmentofBiology,nowtheBiologyProgramme,wasestablishedin1963,andisoneoftheoldestdepartmentsintheUniversity.Indeed,wearethefirstbiologicalsciencesdepartmentinHongKongawardedtheAreaofExcellencebyUniversityGrantsCommittee.Weofferabroadrangeofsubjectsforstudentstochoosefrom,includinggenetics,physiology,plantbiology,zoology,marinebiology,andecology.
Mission�Topreparestudentsforcareersinbiologicalsciencesandrelatedfields� Toprovidestudentswithknowledgeonthelatestdevelopmentsandadvancementsinbiology� To promote excellence in teaching and research in all levels of biological sciences from molecular to
organismalbiology
BIOLOGY
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� Understand the core knowledge in biochemistry coveringbiomolecules,molecularbiology,cellularbiochemistry,metabolism,bioinformatics,proteinsandenzymes
� Gain the knowledge of the latest biochemical technology inclinical biochemistry, immunology, neurosciences, biotechnology,endocrinology,sportandforensicsciences,genomicsandproteomics
�Possess skills in designing experiments to test hypothesis,writingresearchreport,applyingtheirknowledgetodailylife,anddevelopingself-learningcapability
�Becomeall-roundcompetent
ThecurriculumofBiochemistryprogrammecoversdifferentaspectsofbiochemistry.IcanchoosetopicsinwhichIaminterested for in-depth study. There are also abundantopportunities for students to participate in a researchproject. This helps to develop my critical thinking skill.Apart from academic studies, I have also enjoyed thedifferentactivitiesorganizedby theBiochemistrySociety,whichmakemyuniversitylifemoreenjoyableandfruitful.
ChanWai-Wa
Myinterest inclinicalbiochemistryandbiomedicalsciencesgotmetochooseBiochemistryasmymajor.Havingamarvelousteachingteamandmanyinterestingstudytopics,theprogrammeprovidesquality education and numerous research opportunities for us. These help to equip me in manydifferentaspectslikeresearchandcommunicationskills.
WanTsz-Yau
Biochemistry 40th Anniversary High Table Dinner
Studying the stream ecology through fi eld investigation
Appreciating the value of plants in a campus walk
Examining the fl oral structures
Investigating biodiversity at a rocky shore
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Biology (BIOL)
Study Focus: Elective Areas:� Ecology � Microbiology,EvolutionaryBiology,Plant,Marine&AnimalBiology,
� Genetics DevelopmentalBiology,ConservationBiology,Physiology,FieldStudy
� Biodiversity � Advancedtopicsofferedbyotherprogrammes:
� FundamentalsofBiochemistry& Biochemistry:BioenergeticsandMetabolism,MolecularBiology,
CellBiology Immunology,Endocrinology
� FundamentalsinOrganicChemistry, Cell & Molecular Biology: ProteinTraffickingandFolding,StemCellBiology,
Mathematics,andPhysics CellBiologyofCancerandNeuronalSystem
Environmental Science:PollutionandToxicology
Food & Nutritional Sciences:FoodMicrobiology
Molecular Biotechnology:MolecularBiotechnology
Statistics: Biostatistics
Curriculum
Curriculum HighlightsThree recommended packages based on the different combinations of the courses offered by BiologyProgramme:(1)OrganismicBiology;(2)HumanBiology;and(3)BiologyforTeachingCareer.
Expected learning outcomes� Acquirebasicknowledgeinallaspectsofbiologicalsciencesandin-depthunderstandinginatleastone
majorareaofbiology� Developskillsinscientificproblemsolving,statisticsandinformationtechnology� Understandthelatestdevelopmentsandadvancementsinbiology� Appreciatetheimportanceofbiologicalconservationandenvironmentalissues
Views of current students
After finishing my associate degree in Health Studies at HKCC, I joined CUHK due to its diversechoices in life sciences. Finally, I picked Biology as my major because I think Biology is a veryinterestingtopicandtheknowledgeacquiredhelpspreparemyselftofurtherstudyinbiomedicalsciences,suchasmusculoskeletalmedicineandrehabilitation.
YauMan-Ho
TheBiologyProgrammeoffersnumerouscourseswhichcovermany topics inbiologicalsciencesfromtinymicroscopiccells to themacroscopicecosystem,and italsohasstudypackageswhichhelpusplanourcareerpathupongraduation.Inaddition,careertalksareorganizedbytheBiologySocietyannuallyforourbetterunderstandingtowardspossiblejobopportunities.
LeungHill-ToneJessica
ContactWebsite:www.bio.cuhk.edu.hkEmail:[email protected]:852-3943-6249
ProgrammeDirector:[email protected]
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Winter Camp BBQ gathering of students and teachers
Sampling water from the sea
| SCHOOL OF LIFE SCIENCES
BackgroundCell and molecular biology is the foundation of contemporarylife sciences and represents the frontiers of modern biology andbiomedicine.Withthecompletionofgenomeprojectsinhumanandan increasing number of different organisms, the focus of modernbiology is quickly shifting to functional genomics which aims atunderstanding the functions of genes at molecular, cellular, andorganismlevels.
It is in this background that the University proudly launched thenew Cell and Molecular Biology programme in 2008. As the firstprogramme focusing on cell and molecular biology in the region,we target to train superior professionals that fulfill the increasingmanpowerdemandforthecutting-edgeresearchesinthefieldsofcellbiologyandmolecularbiology.Theseadvancedscientificdisciplinesincludestemcellbiology,cancercellbiology,neurobiology,signalingtransduction,anddevelopmentalbiology.
Mission
Cell & Molecular Biology
Curriculum Highlights� STOTcoursesconductedineitherasmallclassor1student-on-1teacherbasis� Intensiveproject-basedlabtraining� Extensivecoverageofcontemporaryandadvancedtopicsincellandmolecularbiologyontopofthe
solidknowledgeinlifesciences
Cell and Molecular Biology (CMBI)
Study Focus: Elective Areas:� ResearchmethodsandScientificcommunication � IndependentresearchinCell&MolecularBiology
� StemCellBiology,CellBiologyofCancerand � AdvancedtopicsofferedbyotherSLSprogrammes:
NeuronalSystem Biology:Physiology,DevelopmentalBiology
� Genomics,Transcriptomics&Metabolomics Biochemistry:Clinicalbiochemistry,Neuroscience,Immunology� ContemporarytopicsinCellBiologyand MolecularBiotechnology:Animal,PlantandMicrobial
MolecularBiology Biotechnology,andGeneticEngineering
FundamentalsinBiochemistryandGenetics � BiomedicalEngineeringofferedbytheFacultyofEngineering
FundamentalsinOrganicChemistry, � Statistics:Biostatistics
Mathematics,andPhysics
Curriculum
� Toprovidethebesteducationandtrainingthatpreparestudentswithprofessionalresearchcompetenceinbiologicalandbiomedicalsciencesaswellasbiotechnology
� Tobecomearegionaleducationcentrewithinternationalrecognitionandapremierresearchhubforcutting-edgeresearchincellandmolecularbiology
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| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Expected learning outcomes� Acquiresolidsubjectknowledgeinthefieldsofcellbiologyandmolecularbiology� Comprehendlaboratoryskillsessentialforaresearchcareer� Possessall-roundcompetence
Views of current students
This one-to-one STOT learning scheme provides studentswith an extraordinary angle to appreciate the wonderfulscientific world. Family-like atmosphere in CMB allowsgood interactions among teachers, staff and students.The project- based CMBI lab courses are fascinating. Notonlythatwelearnttheessentialtechniquesformolecularcloning, we also worked with plant cells and mammaliancellsforourcellbiologyprojects.
MaTsz-ChingCharlotte
Marvelousteachingteam,niceresearchfacility,interestingstudy topics, and constructive career development aresomeofthemanyreasonsthatIwouldrecommendCMBtoyou.Theskillsinwriting,presentation,criticalthinking,andscientificresearchhavewellpreparedmetobeascientifiresearcher.
KwokChun-HoLeo
ContactWebsite:www.cuhk.edu.hk/cmb/Email:[email protected]:852-3943-1361
ProgrammeDirector:[email protected]
BackgroundEnvironmental Science is an integrated science usingthe basic knowledge and skills of applied biochemistry,biologyandchemistrytoassessandresolveenvironmentalproblems. In response to the growing public concernsabout the environmental protection and conservationissues, the University established the EnvironmentalScienceprogrammein1994.
We foster our students with training in ecology,environmental chemistry, pollution control, wastemanagement, biodiversity, conservation, toxicology andhealth,energyresearch,environmentalimpactassessment,andpolicydevelopment.OurbodyoflecturingstaffcomprisesprofessorsfromtheSchoolofLifeSciencesandDepartmentofChemistry,aswellasotherprofessionalsfromrelateddisciplines.Inaddition,ourAdvisoryCommittee,composedofthespecialistsfromtheGovernment,industries,andotheracademicsectors,alsoprovidespreciousadviceoncurricularmatters,thusimprovingtherelevanceofourgraduatestothelocalneedinparticular,andthatofoverseasaswell.
Mission� To provide wide multidisciplinary background in environmental sciences with good communication
skills� Tocultivatehighlevelofcompetenceinscientificunderstandingofenvironmentalissueswithcreative
ideainsolvingenvironmentalproblems� Totrainourstudentswiththeappropriateprofessionaltechniquesinaddressingdifferentenvironmental
issues
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ENVIRONMENTAL Science
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Curriculum Highlights� Electivecourses fromtheDepartmentofGeographyandResource
Management in Faculty of Social Science and the Public HealthProgramme in Faculty of Medicine, such as, Urban EnvironmentalProblems, Ecosystem Restoration and Management, HydrologyandWaterResources,Biostatistics,SoilScience,EnvironmentandHealth,etc.
� ElectivecoursesfromChemistryandEarthSystemScienceinFacultyof Science, and Energy Engineering in Faculty of Engineering, suchas Energy Utilization and Human Behavior, Atmospheric Science,ChemistryinBiofuel,etc.
Expected learning outcomes� Understand the core knowledge covering environmental chemistry,
biologicalconservation,toxicologyandenvironmentalimpacts
� Developtobeanactiveresearcherandprofessionalinvariousaspectsofenvironmentalsciencewithinnovativeideas
� Adapt to fast-changingsocialenvironment tostaycompetitive in jobmarket and be aware of the latest developments in environmentalpolicyandissues
Enviromental Science (ENSC)
Study Focus: Elective Areas:� Ecology � ChemistryinBiofuels
� EnvironmentalChemistry&Instrumentations � ChemicalTreatmentProcesses
� EnvironmentalImpactAssessments � ConservationBiology
� EnvironmentalandBiochemicalToxicology � EnvironmentalBiotechnology
� Internship � EnvironmentalProtection&PollutionControl
� EnvironmentalHealth
� FieldStudy
� HongKongFloraandFauna
� MarineBiology
� MethodsinToxicologicalResearch
� Electivesfromotherprogrammes
Curriculum
Career prospectHalfofourgraduatesdirectlyinvolveinenvironmentalrelatedjobsaftergraduation.Theyworkingovernmentdepartments, consulting firms, green groups, and commercial sectors focusing on various aspects ofenvironmentalissues,fromgreenpurchasing,carbonaudit,toenvironmentalimpactassessmentsandtreemanagement.Othergraduatesbecomepost-graduatestudentsorfindjobsinschoolsasteachers,inthebusinesssectorsasadministratorsormarketingofficers.
Views of current studentsI am a final year student studying environment science. Throughout my three-years university life,myundergraduatecurriculumenablesmeto learnawidevarietyofenvironmentalmanagementandprotectiontopics,Ihavegainedextensiveknowledgeinmystudiesanddevelopedasamulti-dimensionthinker.Ihavefoundanareainwhichmycuriosityandmyabilityaresuitablypaired.Inmyfinalyear,IhavetakenDirectResearchProject forstrengtheningmy laboratoryskillsand independentworkingability. Furthermore, it would be a valuable to have a preliminary experience being a scientist. Thisprogrammeprovidesanumberofelectivecoursesfromotherrelevantdepartment,fieldstudies,aswellasencouragingthedevelopmentofaspiringenvironmentalistsdirectlyinclassroomandlaboratory.
MakChuWa
Iamafirstyearstudent inENSC.Classmatesare friendlyandwilling tohelp in theprogramme.Inthisyear,Ihavelearntbasicknowledgeabouttheenvironmentalproblemsandtheirsolutions,whichareessentialformetoworkintheenvironmentalaspectlateronaftergraduation.
SiuHoi-Ying
ContactWebsite:www.cuhk.edu.hk/ens/Email:[email protected]:852-3943-6294
ProgrammeDirector:[email protected]
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| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |53 54
Food & Nutritional Sciences
BackgroundFoodsafetyandhealthyeatingthatimprovethequalityoflifehavebecomeaneverydaycriticalawareness.Therapidadvanceandexpansionoffood-relatedindustriesfurtherposenewchallengesandresearchopportunitiesinfoodandnutritionalsciences.
In response to the increasing demand of manpower for food science andnutritional studies, the University established the Food and NutritionalSciencesprogrammein1994.Weareintendedforstudentswhoareinterestedinmodernfoodandnutritionalsciences,andtheirdiverseapplicationssuchas
foodsafetyandtoxicology,foodmicrobiology,foodpreservation,foodproductdevelopment,foodanalysis,quality assurance, nutrient metabolism, introductory dietetics, and community nutrition. The specializedtraininginthefieldwithwidescopepreparesourstudentsfortheemploymentintheindustrialandcommercialsectors,ingovernmentandprivatehealthservices,andfoodcateringinstitutesservicesorganizations.
Mission� Toprovidetrainingtostudentsonmodernfoodandnutritionalsciences,withanemphasisonoriental
culturalbackgroundandperspectives
� ToprovideresearchanddevelopmentexpertisethatenhancesandsustainsthecompetitivenessoftheHongKongfoodindustryandhealth/nutritionprofessionsandbusiness.
Curriculum
Food and Nutritional Sciences (FNSC)
Study Focus: Elective Areas:� Nutrition&HumanDevelopment � IndependentresearchinFoodandNutritionalSciences
� FoodChemistry&Analysis � CommunityNutritionandMedicalNutritionalTherapy
NutritionalBiochemistry � FoodTechnologyandProcessing
� GeneralandFoodMicrobiology FoodProductDevelopmentandQualityControl
� FundamentalsofBiochemistry&CellBiology FoodSafetyandToxicology
� FundamentalsinOrganicChemistry, HumanandNutritionalPhysiology
Mathematics,andPhysics AdvancedtopicsofferedbyotherSLSprogrammes:
� Biology:Genetics
� Biochemistry:Immunology,Endocrinology
EnvironmentalScience:EnvironmentalToxicology
MolecularBiotechnology:GeneticEngineering
� Statistics:Biostatistics
Expected learning outcomes� Understand thecoreknowledgeand latest issues in foodandnutritionalsciences thatpromote the
competitivenessofthestudentsinthelabormarket� Acquireabilitiestoaccess,retrieveandcriticallyevaluateinformationrelevanttofoodandnutritional
sciences� Applytheknowledgeoffoodandnutritionalsciencesintoreal-lifepracticalsituations
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |55 56
Views of current studentsThe good reputation and interesting study topics brought meto the CUHK Food and Nutritional Sciences. The contents of themajor courses are good. The knowledge related to food scienceand nutrition well prepares me for future career development.Oneexcellenceaboutthecurriculardesignisthechancestostudydifferenttopicsinlifesciencesbeforeselectingthemajor.
KwokWing-Hang
FoodandNutritionalSciencesprogrammehasanexcellentteamofteachers who are enthusiastic about teaching.They are very kindto offer helping hands. The well being of the students is alwaysprioritized.
YuChi-On
ContactWebsite:www.sls.cuhk.edu.hk/index.php/fnscEmail:[email protected]:852-3943-8137
ProgrammeDirector:[email protected]
BackgroundMolecularbiotechnologyisarevolutionaryareaofscientificdisciplinethat involves the application of gene and protein technology. Thisstate-of-the-art technology has exerted remarkable contributions toagriculturalhealth,environmental,bioenergy,andotherbio-industrialareas. Molecular biotechnology is one of the major driving forcesshapingthedevelopmentofhumansocietyinthe21stcentury.
In view of the current needs of increasing manpower and futureprospects of biotechnology, the University launched the MolecularBiotechnology programme in 1998. We target students who areinterested in genetic engineering, molecular biology, methods inbiochemistry, microbial, plant, and animal biotechnology. Other in-depth knowledge from an array of elective courses covering variousaspectsofcell&developmentalbiology,animalandplantphysiology,immunology and clinical biochemistry, bioinformatic, genomics andproteomics are also provided for students’ selection. In addition, wealso address the business and social implications of biotechnology,such as government policy, management, intellectual property, andethicalandpublicconcerns.
Mission� To provide theoretical and hands-on training to students on the fundamental knowledge, current
development,businessandsocialimplicationsofmolecularbiotechnology� Tocultivatetheabilityoflogicalandcriticalthinking,andscientificcommunications
Molecular Biotechnology
MBT 10th Anniversary Banquet The 10th Anniversary Symposium of the Molecular Biotechnology programme
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Curriculum Highlights� Fundamentalknowledgeinlifesciencewithemphasisonmolecularbiotechnology� Hands-onskillsthroughspeciallydesignedlaboratorycoursesonmethodsinmolecularbiotechnology� In-depthknowledgeinselectedareasofyourchoice.Topicscovervariousaspectsofchallenge’sfields
inbiology&biochemistry� Comprehensive understanding of the business and social implications of biotechnology, such as
governmentpolicy,management,intellectualproperty,andethicalandpublicconcerns
Moleular Biotechnology (MBTE)
Study Focus: Elective Areas:� MolecularBiotechnologyinAnimals,Plants � IndependentresearchinMolecularBiotechnology
andMicroorganisms � AdvancedtopicsofferedbyotherSLSprogrammes:
� Business&SocialAspectsofBiotechnology Biochemistry:ProteinandEnzymes,Bioenergeticsand
� MethodsinMolecularBiotechnology Metabolism,Immunology,ClinicalBiochemistry
� MethodsinBiochemistry Biology:Physiology,DevelopmentalBiology
� Genetics&GeneticEngineering Cell&MolecularBiology:StemCellBiology,CellBiologyof
� CellBiology&DiversityofLife CancerandNeuronalSystem
� Microbiology � Statistics:Biostatistics
� FundamentalsinOrganicChemistry, BiomedicalEngineeringofferedbytheFacultyof
Mathematics,andPhysics Engineering
Curriculum
Visit biotechnology companies Career talk given by alumni
Expected learning outcomes� Gainsolidknowledgeinlifescience,withparticularemphasisontheprinciplesandpotentialapplications
ofmolecularbiotechnologyincludesgeneticengineering,molecularbiology,methodsinbiochemistry,microbialbiotechnology,plantbiotechnologyandanimalbiotechnology
� Acquirehands-onoperationalcapabilityinbasicskillsofmolecularbiotechnology� Understand the business and social implications of biotechnology, such as government policy,
management,intellectualproperty,andethicalandpublicconcerns� Beabletojudgetheprosandconsofvariousapplicationsofmolecularbiotechnologyonhumansociety
andnaturalenvironment� Acquirehands-onoperationalcapabilityinbasicskillsofmolecularbiotechnology� Developcompetitivequalityforfuturecareersinscientificresearchanddevelopment
View of current students
IenrolledtotheUniversityviatheEarlyAdmission Scheme. After the first yearofstudyinlifesciences,Ifoundthatwehad a good chance to know the studytopicsandformatbeforereallychoosingthe preferred major. I have decided tochooseMolecularBiotechnologyformymajor, and it is because its curriculumstrikes an excellent balance betweenbasic science knowledge and technicalskills. In addition, the ample researchchancesandgoodreputationareotherfactorsthatbringmetothisprogramme.
WooTheodosia
ContactWebsite:www.mbt.cuhk.edu.hk/Email:[email protected]:852-3943-6393
ProgrammeDirector:[email protected]
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Graduation
| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |
Minimum Admission RequirementsJUPASAdmission� Students who have taken HKDSE and intend to major in one of the six programmes offered by the
SchoolofLifeSciences,i.e.Biochemistry,Biology,CellandMolecularBiology,EnvironmentalScience,FoodandNutritionalSciences,andMolecularBiotechnology,shouldapplytheSCIENCEbroad-basedadmissionscheme(JUPASCode:JS4601,Science).
Theminimumeligibilitytoapplyis4coreand2electivesubjects(4C + 2X or 4C + M1/M2 + 1X),withtheminimumrequirementsforthe4coresubjectsofChineseLanguage,EnglishLanguage,Mathematics,andLiberalStudiesatlevels3322respectively.
JUPAS Catalogue No. / Elective Requirements (X) Remarks
Programme Subject Level
JS4601- AnyONEsubjectfromthefollowing: Level3 BonuspointswouldSCIENCE -Biology beofferedtothe3rd -Chemistry electivesubjectin -Physics CategoryA. -CombinedScience -IntegratedScience -Mathematics(Module1 or 2)
AnyONEsubjectinCategoryA# Level3
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Non-JUPASAdmission� AcquiretheInternationalBaccalaureateDiploma;OR� Obtain good grades in Hong Kong Advanced Level (HKAL) Examination or GCE Advanced Level
ExaminationwithnolessthanthreeAdvancedLevelsubjects;OR� Possessaqualificationwhichqualifiesforuniversityadmissionintheissuingcountry(e.g.SATinUSA,
UEC/STPMinMalaysia,ATARinAustralia,OSSDinCanada);OR� Completedanassociatedegreeorhigherdiploma
MoredetailscanbefoundinthewebpageofOfficeofAdmissionsandFinancialAid.
#Preferredsubjects:Biology,Chemistry,Physics,CombinedScience,Economics,Geography,Informationand CommunicationTechnology,IntegratedScience,Mathematics(Module1or2),andTechnologyandLiving(Food Science&Technology)
GeneralOfficeoftheSchoolofLifeSciencesRoom132,ScienceCentreNorthBlockTel:3943-6122Email:[email protected]:www.cuhk.edu.hk/lifesciences/
Copyright©2016SchoolofLifeSciences,FacultyofScience,TheChineseUniversityofHongKong.AllRightsReserved.