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Programmes of theSchool of Life Sciences 生命科學學院課程•Biochemistry

•Biology

•Cell&MolecularBiology

•EnvironmentalScience

•FoodandNutritionalSciences

•MolecularBiotechnology

Faculty of Science | 理學院

Table of Contents

Message from the Director 01

Establishment of the School of Life Sciences 02

Why SLS at CUHK? 03

High Diversity in Life Sciences 04

CourseListfor4-yearCohort(2016-17)

StudyScheme

ExamplesofcoursepatternsfortheExplorationphase

World Class Education 11

Excellent Research 18

BreakingNews

AcademicHonoreesandAwardees

ResearchintheSchool

ResearchInstitutesandCenters

Ample Opportunities 31

Good Internationalization 34

Outstanding Career Prospects 35

Individual Programmes 40

Biochemistry

Biology

Cell&MolecularBiology

EnvironmentalScience

Food&NutritionalSciences

MolecularBiotechnology

Minimum Admission Requirements 59

Contact 60

| SCHOOL OF LIFE SCIENCES

Establishment ofthe School of Life Sciences

–ProfessorWongKam-Bo

Year Event

1963 EstablishedDepartmentofBiology

1971 EstablishedDepartmentofBiochemistry

1994 EstablishedEnvironmentalScienceProgramme, jointlybyDepartmentsofBiochemistry,Biology,andChemistry

EstablishedFood&NutritionalSciencesProgramme,jointlyby DepartmentsofBiochemistryandBiology

1998 EstablishedMolecularBiotechnologyProgramme,jointlyby DepartmentsofBiochemistryandBiology

2008 EstablishedCell&MolecularBiologyProgramme

2009 LaunchedLifeSciencesBroad-basedAdmissionScheme

2010 EstablishedtheSchoolofLifeSciences

01

TheSchoolofLifeScienceswasestablished

in 2010 under the Faculty of Science by

merging theDepartmentsofBiochemistry

and Biology, which are among the oldest

departmentsinCUHK.OurSchoolofferssix

majorprogrammes:Biochemistry,Biology,

Cell & Molecular Biology, Environmental

Science, Food & Nutritional Science, and

Molecular Biotechnology, which have

trained over 8400 alumni over the years.

Our curriculum is designed to meet the

diverse interests of life science students.

The students will receive training in fundamental knowledge in life sciences in their junior

years,beforetheyspecializeintooneofthesixprogrammesintheirsenioryears.

In addition to quality teaching, we also strive for excellence in research. For example, two

researchprojects“PlantandAgriculturalBiotechnology”and“CentreforOrganelleBiogenesis

andFunction”ledbyourschoolhavebeenselectedbytheUniversityGrantsCommitteeasone

oftheAreas-of-ExcellenceinHongKong.Webelievethatthebestwaytotrainfuturegeneration

ofscientistsistoinspirethestudentsandgivethemtheopportunitiestotakepartincutting-

edgeresearchthemselves.Tothisend,wehavetheSMART(youngScientistMentorshipAnd

ResearchTraining)andDREAM(DedicatedResearchExchangeAndMentorship)programsto

allowmotivatedstudentstoengageinresearchinlocalandoverseaslaboratories.Toequipour

studentswithaglobalperspectiveandenhancetheirlearningexperienceinaworld-renowned

university,wehaveintroducedaBerkeleyBiosciencesStudyAbroad(BBSA)Programme,which

enablesourstudentstospendasemesterinUCBerkeley.

If you are interested in the science of living organisms - from the structure and function of

DNAandproteinstotheinteractionsamonglivingorganismsinanecosystem;frompreparing

a career in environmental protection, food technologists, or nutritionists to research and

development of biotechnological products - you will find our diverse courses and flexible

curriculumfityourinterests.

Message from the Director

| SCHOOL OF LIFE SCIENCES

Why SLS at CUHK?

HighdiversityinlifesciencesThe School provides highly diverse and sophisticated courses in life sciences. Study topics cover frombiomoleculestoecology.AndtheflexiblecurriculumofferedbytheSchoolalsofitstheneedsofindividualstudents.

WorldclasseducationTheextraordinaryreputationofourprogrammesandtheexcellentquality ineducationarecommendedandaffirmedbytheQualityAssuranceCounciloftheHongKongUniversityGrantsCommittee(UGC).

ExcellentresearchThe School has a marvelous team of teachers who are field-pioneers and outstanding researchers. Forinstance,ourplantbiotechnologyresearchisanAreaofExcellence,withtheestablishmentoftheState-key laboratoryofAgrobiotechnology.Withavarietyof thestate-of-the-artequipmentandourexcellentresearchpersonnel,weensurethatourresearchshallcontinuetoprosper.

AmpleopportunitiesWe provide incomparable undergraduate research opportunities, for instance DREAM and SMARTprogrammes,andthesechancesaresomethingdifficulttofindinotherinstitutes.Studentswillalsofindnumerousexchangeandinternshipopportunitiesthatthelearningexperiencewillnotbeconfinedtothetextbooks and classrooms. A newly introduced Berkeley Biosciences Study Abroad (BBSA) Programmeenables selected students to study in UC Berkeley for a term with subsidies. In addition, plentiful ofotheractivitiesalsohelp todevelop theall-roundcompetence.Numerousscholarshipsareprovided tooutstandingstudentsthroughoutthestudies.

HighinternationalizationOurprogrammesattractlocalandoverseasstudents.Thisenablesstudentstoappreciatedifferentcultures,honelanguageskillsandgrowasconfidentindividuals.

OutstandingcareerprospectsAccording to the recent career survey of our graduates, the distribution of the work type of therespondents is as follows: 45% in scientific/research work and medical & health service; 10% inadministration/management; 15% in business/commerce; 6% each in environmental science,mediaandteaching,therestinhotel/tourism,disciplinedservice,construction/architecture,humanresource/trainingandlogistics/shipping,etc.

High Diversity in Life Sciences

03

High Diversity in Life Sciences

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

TheSchoolofLifeSciencesofferssixprogrammesthatfocusonthestudyofanextensiverangeoftopicsinallaspectsoflifesciences.

Intotal,weprovideover130coursesattheundergraduatelevelforourstudents.Inadditiontothelecturecourses,morethan40%ofthecoursestheSchooloffersarelaboratoriescourses,workshops,student-orientedteachingcourses,independentstudymodules,andsupervisedresearchcourses.Thiswidevarietyofcourseformatandcoursecontentfacilitatestheestablishmentofthesolidknowledgefoundationinlifesciences,andfostersthedevelopmentofstudents’all-roundcompetence.

Course Code Course Title Unit(s)LSCI1000 BiochemistryofHealthandDisease 3LSCI1001 BasicConceptsinBiologicalSciences 3LSCI1002 IntroductiontoBiologicalSciences 3LSCI1003 LifeSciencesforEngineers 3LSCI2002 BasicLaboratoryTechniquesinLife 2 SciencesLSCI2003 ScientificConductandEthics 2LSCI3000 SyntheticBiologyWorkshop 2LSCI4000 LiteratureResearchinLifeSciences 3

Course Code Course Title Unit(s)BIOL2120 CellBiology 3BIOL2210 Ecology 3BIOL2213 EcologyLaboratory 1BIOL2313 GeneticsLaboratory 1BIOL2410 GeneralGenetics 2BIOL3012 BiodiversityLaboratoryI 2BIOL3022 BiodiversityLaboratoryII 2BIOL3310 HumanBiology 3BIOL3410 GeneralMicrobiology 3BIOL3413 MicrobiologyLaboratory 1BIOL3530 PlantPhysiology 3BIOL3560 BiologyofFungiandNon-VascularPlants 2BIOL3570 BiologyofVascularPlants 2BIOL3610 InvertebrateFormandFunction 2BIOL3620 VertebrateLife 2BIOL3630 AnimalPhysiology 3BIOL3710 MarineBiology 3BIOL4010 EvolutionaryBiology 3BIOL4012 FieldandEnvironmentalBiology 2BIOL4032 PhysiologicalInvestigations 2BIOL4120 DevelopmentalBiology 3BIOL4220 EnvironmentalBiotechnology 3BIOL4260 ConservationBiology 3BIOL4310 HumanGenetics 3BIOL4510 HongKongFloraandVegetation 3BIOL4901 SeniorExperimentalProjectI 2BIOL4902 SeniorExperimentalProjectII 2BIOL4903 SeniorExperimentalProjectIII 2BIOL4906 Internship 2BIOL4907 FieldStudy 2

Course Code Course Title Unit(s)FNSC2001 IntroductiontoFoodSci&Technology 2FNSC2002 NutritionforHealth 2FNSC3001 FoodSciLabI 2FNSC3002 NutritionalSciLabI 2FNSC3010 NutritionandHumanDevelopment 3FNSC3030 NutritionalBiochemistry 3FNSC3110 FoodChemistryandAnalysis 3FNSC3180 FoodMicrobiology 3FNSC4001 FoodSciLabII 2FNSC4002 NutritionalSciLabII 2FNSC4110 FoodTechnology 3FNSC4120 CommunityNutrition 3FNSC4150 IntroductiontoMedicalNutritionTherapy 3FNSC4160 NutritionPlanningandFoodPolicy 3FNSC4170 FoodProductDevelopmentandQuality 3 ControlFNSC4901 SeniorExperimentalProjectI 2FNSC4902 SeniorExperimentalProjectII 2FNSC4903 SeniorExperimentalProjectIII 2FNSC4906 Internship 2FNSC5130 HumanPhysiology 3FNSC5320 NutritionalPhysiology 3FNSC5430 FoodToxicologyandSafety 3

Course Code Course Title Unit(s)CMBI2200 LiteraturesurveyinCMBandScientific 2 CommunicationCMBI2500 ResearchInternship 2CMBI3010 CMBLaboratoryI 3CMBI3020 CMBLaboratoryII 3CMBI3030 CMBLaboratoryIII 1CMBI3040 CMBLaboratoryIV 1CMBI3100 MethodologyofCriticalThinkinginCMB 2CMBI3101 BiologyofModelOrganismsforCMB 3 ResearchCMBI3200 ProposalFormulationandCreative 2 ScientificWritinginCMBCMBI4001 ProteinTrafficking 1CMBI4002 ProteinFolding 1CMBI4003 SignalTransduction 1CMBI4101 CancerCellBiology 1CMBI4102 StemCellBiology 1CMBI4103 NeuronalCellBiology 1CMBI4201 GenomicsandTranscriptomics 1CMBI4202 Proteomics 1CMBI4203 Metabolomics 1CMBI4301 CurrentTopicsinCellBiology 1CMBI4302 CurrentTopicsinMolecularBiology 1CMBI4303 CurrentTopicsinBiotechniques 1CMBI4901 SeniorExperimentalProjectI 2CMBI4902 SeniorExperimentalProjectII 2CMBI4903 SeniorExperimentalProjectIII 2

Course Code Course Title Unit(s)ENSC2270 IntroductiontoEnvironmentalScience 3ENSC2515 EnvironmentalChemistry 3ENSC2517 EnvironmentalChemistryLaboratory 2ENSC3230 PrinciplesofEnvironmentalProtection 3 andPollutionControlENSC3415 EnvironmentalInstrumentationTechniques 3ENSC3417 EnvironmentalInstrumentationTechniques 2 LaboratoryENSC3520 EnvironmentalandBiochemicalToxicology3ENSC3820 EnvironmentalandBiochemicalToxicology 2 LaboratoryENSC4210 EnvironmentalPollutionandToxicology 3ENSC4240 EnvironmentalImpactAssessment 3ENSC4242 EnvironmentalImpactAssessmentLaboratory2ENSC4250 EnvironmentalHealth 3ENSC4310 MethodsinToxicologicalResearch 3ENSC4510 MethodsinToxicologicalResearchLaboratory 2ENSC4525 AdvancedEnvironmentalChemistry 3ENSC4535 ChemicalTreatmentProcesses 3ENSC4901 SeniorExperimentalProjectI 2ENSC4902 SeniorExperimentalProjectII 2ENSC4903 SeniorExperimentalProjectIII 2ENSC4906 Internship 2ENSC4907 FieldStudy 2

Course Code Course Title Unit(s)MBTE2000 IntroductiontoMolecularBiotechnology 2MBTE2010 DiversityofLife:Applicationsand 2 SustainabilityMBTE3000 BusinessandSocialAspectsof 3 BiotechnologyMBTE4033 MethodsinMolecularBiotechnology 2 LaboratoryIMBTE4034 MethodsinMolecularBiotechnology 2 LaboratoryIIMBTE4320 GeneticEngineering 3MBTE4510 PlantBiotechnology 3MBTE4520 AnimalBiotechnology 3MBTE4530 MicrobialBiotechnology 3MBTE4901 SeniorExperimentalProjectI 2MBTE4902 SeniorExperimentalProjectII 2MBTE4903 SeniorExperimentalProjectIII 2MBTE4906 Internship 2

Course List for 4-year Cohort (2016-17)Life Sciences Biology

Food and NutritionalCell and Molecular Biology

Enviromental Science

Molecular Biotechnology

Course Code Course Title Unit(s)BCHE2000 FrontiersinBiochemistry 2BCHE2030 FundamentalsofBiochemistry 3BCHE2070 ResearchInternship 2BCHE3030 MethodsinBiochemistry 3BCHE3040 ProteinsandEnzymes 3BCHE3050 MolecularBiology 2BCHE3070 RecombinantDNATechniques 1BCHE3080 BioenergeticsandMetabolism 3BCHE3090 Self-studyModulesinBiochemistry 2BCHE3650 MolecularBiologyandRecombinant 2 DNALaboratoryBCHE3730 AnalyticalBiochemistryLaboratory 2BCHE4030 ClinicalBiochemistry 3BCHE4040 AspectsofNeuroscience 3BCHE4060 BasicandAppliedImmunology 3BCHE4080 BiochemistryforForensicSciences 2BCHE4090 BiochemistryforSportandExercise 2BCHE4130 MolecularEndocrinology 3BCHE4760 ImmunologyandHaematologyLaboratory 2BCHE4830 MedicalBiochemistryLaboratory 2BCHE4901 SeniorExperimentalProjectI 2BCHE4902 SeniorExperimentalProjectII 2BCHE4903 SeniorExperimentalProjectIII 2

Biochemistry

05 06

| SCHOOL OF LIFE SCIENCES

Study SchemeStarting from 2012, students who wish to choose Biochemistry, Biology, Cell & Molecular Biology,EnvironmentalScience,Food&NutritionalSciences,andMolecularBiotechnologyastheirmajorsarefirstnecessarytoenroll intheScienceProgramme(JS4601).Then,theybegintheirfirstphaseofstudy,whichcomprises thefirst3 terms, tostrengthen thebasicknowledge ingeneralscience. InTerm1andTerm2,studentsarerecommendedtofinishtheFacultyPackagewhichsecuresawideexposuretorelateddisciplines.ThisPackageincludes2introductorycoursesinlifescienceandchemistry,plus1electivecourseinphysics,mathematicsorstatistics.Afterward,inTerm3, 3coursesonthefundamentalsofbiochemistryandbiologyarecompulsorytostudents.Thesecourseswellserveasthesolidfoundationsforthesubsequentspecializedmajorstudiesinlifescience.

Thenextphaseoftheundergraduatestudyhelpstounderstandinmoredetailofthe6majorprogrammesintheSchoolofLifeSciences.InTerm4,studentscanchooseclassesfrom14differentcoursesofferedby our programmes. To avoid possible overloading, students are recommended not to take more than13unitsofmajorcourses.Nonetheless,thislimitationcanalreadyaccommodatetherequirementsofupto3majorstoacquiretheirpreliminarysavors.Throughthisflexiblecourse-selectingscheme,studentscancomprehendtheirspecificinterestsinthediversefieldsinlifesciencesandformulatetheirbestfittingchoiceforthemajors.

a choose only ONE laboratory course from BIOL2213, BIOL2313 or BIOL3413 (offered in the second year) for the major requirement of BIO.

General Study Scheme for entrants from 3-3-4 curricular system

Term 1

Term2

Term3

Term4

Term5

Term6

Term7

Term8

with foundation courses in life sciences in Term 3:LSCI2002+BIOL2120 +BCHE2030

Build up fundamental knowledgewith Faculty Package in Terms 1 and 2

LSCI1002* + CHEM1280 or CHEM1070 + onecoursefromMaths,Physics,Statistics.

Confi rm your interestSelect preferred courses from a list of 14 offered by all 6 programmes

BCHE2000 BCHE3050 BCHE3070 BCHE3650 BIOL2210 BIOL2213 BIOL2313 BIOL2410 CMBI2200 ENSC2270 FNSC2001, 2002 FNSC3180 MBTE2000 MBTE2010

Foster to be a specialistEngage in the advanced and specialized study

posed by your Major program

* Students who do not have high school Biology should take LSCI1001 prior to LSCI1002.

BCHE2000

BCHE3050

BCHE3070

BCHE3650

BIOL2210

BIOL2213

BIOL2313

BIOL2410

CMBI2200

ENSC2270

FNSC2001

FNSC2002

FNSC3180

MBTE2000

MBTE2010

Course code Unit BCHE BIOL CMBI ENSC FNSC MBTE

2

2

1

2

3

1

1

2

2

3

2

2

3

2

2

07

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Examples of course patterns for the Exploration phase� Example 1:Alancanneverresistthetemptationfromfood.Startingfromseveralyearsago,theissuesofmalachitegreenandnitrofuranresiduesfoundinfreshwaterfish,Sudandyesineggsaswellasmelamineindairyproductshadarousedhisawarenessinthescienceoffoodsafety.Hence,hedecidestomajorinFNSC.

� Example 2:Jacksonenjoysnatureandoutdooractivities.Wheneverhehasachance,hewouldgocampingordivingwith his friends. However, it frustrates him a lot lately as he can hardly find a nice local place for theactivities due to pollution or urbanization. He wonders if he can contribute something to preserve ourplanet.Therefore,hewantstofocusonthestudyofbiodiversityandenvironmentalscience.

� Example 3:JennyisinterestedinthestudyofDNAandproteins,andwishestofindoutmoreaboutBCHE,CMBI,andMBTEbeforeshemakesafinaldecisiononhermajor.

Suggested course pattern in second term for:

Example 1: Alan

Course Unit

BIOL2410 2

FNSC2002 2

FNSC3180 3

1majorelective 3

Example 2: Jackson

Course Unit

BIOL2210 3

BIOL2213 1

BIOL2410 2

ENSC2270 3

Example 3: Jenny

Course Unit

BCHE2000 2

BIOL2410 2

BIOL2313 1

CMBI2200 2

MBTE2000 2

Total: 10 Total: 9 Total: 9

Afterthesecondphaseofstudy,studentsshouldfinalizetheirdecisionsonmajorselectionaccordingtotheirinterests.Thereare 3occasionsonwhichstudentscandeclaretheirmajor:afteradmission,bytheendofthefirstyearandbytheendofthesecondyearofstudy.Dependingonthepre-definedacademicachievements,studentscandeclaretheirmajoronanyoneofthe3occasionswithinthefirst2yearsofstudy.

Aftermajordeclaration,inthefinalphasewhichisbasicallythelast4terms,studentstakecoursestofulfillthestudyrequirementposedbythespecificmajortograduate.

Condition

* Apply to FNSC only

BiologyOR

ChemistryOR

CombinedScience(withBiologyorChemistrycomponent)ORIntegratedScienceOR

TechnologyandLiving*(FoodScienceandTechnologyStrandonly)

Level 5 or above in HKDSE of

LSCI1002

C+ or above in

LSCI1002,LSCI2002,

BCHE2030AND

BIOL2120

Taken(NOT necessarily ALL PASSED)

Declaration occasion After admission End of Year 1 End of Year 2

09 10

SCHOOL OF LIFE SCIENCES |

The Hong Kong University Grants Committee (UGC) stated that the University‘provides high quality student learning experience that refl ects its mission and role statement, underpinned by good quality assurance systems’.

Thismerit,ofcourse, isnottheonlyaffirmation.HongKongEconomicJournalMonthlyrankedCUHKtobe the top among the other UGC-funded universities.The six major criteria included the percentage ofPhDholdersforacademicstaff,JUPASadmissionresults,teachingqualities,financialresources,qualityofgraduates,andresearchperformance.

Indeed,thefacultymembersfromtheSchoolofLifeScienceshavebeenrecognizedtobecommendablethatoverthelastfewyears,ourteachershavebeenreceivingvariousteachingawards.

Vice Chancellor’s Exemplary Teaching Award Exemplary Teaching Award in General Education

Year Awardees2002 ProfessorLeeSau-TuenSusanna2003 ProfessorGeWei2007 ProfessorGeWei2008 ProfessorLeungKwok-Nam2012 ProfessorKongSiu-Kai

Year Awardees2012 Dr.ChiuChi-Ming Lawrence

Teachers in the School of Life Sciences

Chan Michael Kenneth, PhD (UC Berkeley)Email:[email protected]

ResearchInterests:1.Proteincrystallography2.Chemicalbiology

Director

12

World Class Education

World Class Education

Chan Ho-Yin Edwin, PhD (Cantab)Director,M.Sc.ProgrammeinBiochemicalandBiomedicalSciencesEmail:[email protected]

ResearchInterests:1.Cellular,geneticandbiochemical

analysesofRNAandproteintoxicityinneurologicaldiseases

2.Humandiseasemodelling

Professors

Wong Kam-Bo, PhD (Cantab)Director,SchoolofLifeSciencesEmail:[email protected]

ResearchInterests:1.Structure-functionstudiesofproteins2.Structure-determinationofproteinsby NMRspectroscopyandX-raycrystallography3.Proteinengineeringanddesign4.Simulationandmodelingofproteins

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Au Wing-Ngor Shannon, PhD (HK)Email:[email protected]

ResearchInterests:1.Proteinpost-translational modification2.Macromolecularassembly

Chan King-Ming, PhD (Nfl d.)Director,EnvironmentalScienceProgrammeEmail:[email protected]

ResearchInterests:1.Aquatictoxicology2.Molecularendocrinology3.Marinebiotechnology4.Environmentalpolicy

Chan Ting-Fung Philos, PhD (Wash.)Email:[email protected]

ResearchInterests:RNAgenomicsandbioinformatics:1.Functionsandregulationsof non-codingRNAsinbiological processesanddiseases;2.Genotype-phenotyperelationships incomplexdiseasesortraits;3.Softwaredevelopmentforhigh-throughputdataanalysis;4.Applicationsinsyntheticbiology

Wong Po-Keung, PhD (UC Davis)AssociateDirector,EnvironmentalScienceProgrammeEmail:[email protected]

ResearchInterests:1.Environmentalbiotechnologyand

microbiology2.Environmentaltechnology3.Ecotoxicology

Zhang Jian-Hua, PhD (Lancaster)Email:[email protected]

ResearchInterests:1.Plantphysiologyandmolecular

biologyunderenvironmentalstresses2.Cropphysiologyandcropproduction

Jiang Liwen, PhD (S. Fraser)Director,CellandMolecularBiologyProgrammeDirector,CentreforCellandDevelopmentalBiologyEmail:[email protected]

ResearchInterests:1.Cellandmolecularbiology2.Proteintargetingandtrafficking3.Plantendocytosisandexocytosis4.Organelledynamicsandbiogenesis5.Plantbiotechnology

Kong Siu-Kai, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Developmentofbiosensors2.Erythropoiesisandapoptosis3.Mitochondriaasregulatorsof

celldeath4.Cancerbiochemistry

Lam Hon-Ming, PhD (Northwestern)Director,MolecularBiotechnologyProgrammeEmail:[email protected]

ResearchInterests:1.Genomicstudyofsoybean2.Identificationandcharacterization offunctionalgenestoimprove

abioticstresstoleranceanddiseaseresistanceinplants;

3.Manipulationofnitrogensink-sourcerelationshipinplants

Shaw Pang-Chui, PhD (Lond.)Director,BiochemistryProgrammeDirector,CentreforProteinScienceandCrystallographyEmail:[email protected]

ResearchInterests:1.Structure-functionstudiesofproteins2.AuthenticationandqualitycontrolofChinese

medicinalmaterial

Associate Professors

13 14

Chen Zhen-Yu, PhD (Mass.)DivisionHead,ResearchPostgraduateProgrammesEmail:[email protected]

ResearchInterests:1.Cholesterolmetabolismandheart

diseases2.Antioxidantsandfreeradicals3.Fattyacidsandhealth

Cheung Chi-Keung Peter, PhD (NSW)AssociateDirector,FoodandNutritionalSciencesProgrammeEmail:[email protected]

ResearchInterests:1.Structure-functionofcellwall

polysaccharides2.Bioactivesubstancesfrom

mushroomandediblefungi3.Chemicalpropertiesandbiological

functionsofdietaryfiberandprebiotics

4.Functionalfoodsandnutraceuticals

Chu Ka-Hou, PhD (MIT/WHOI)Director,BiologyProgrammeDirector,SimonF.S.LiMarineScienceLaboratoryEmail:[email protected]

ResearchInterests:1.Molecularmarinebiologyand

biotechnology2.Biologyofcrustaceans

Fong Wing-Ping, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Structureandfunctionofantiquitin2.Anti-tumoreffectsofnovel photosensitizersin photodynamictherapy3.RoleofmiR-200inovariancancer development

.Structure-functionstudiesofproteins

.AuthenticationandqualitycontrolofChinese

Chu Lee-Man, PhD (Liv.)Email:[email protected]

ResearchInterests:1.Industrial,restorationand

urbanecology2.Pollutionstudies

Chung Hau-Yin, PhD (Louisiana State)AssociateDirector,FoodandNutritionalSciencesProgrammeEmail:[email protected]

ResearchInterests:1.Foodflavorchemistry,analysis

andapplication2.Naturalproduct,safety,health

andapplication3.Foodevaluationandfoodproduct

development4.Soy-basedfermentedfoodandseafood

Guo Dian-Jing Diane,DS(ChineseAcad.ofSc.)Email:[email protected]

ResearchInterests:1.Genomicsandbioinformatics2.Systemsbiology3.Plantstressresponse4.Plantsecondarymetabolismand trichomefunction

Kang, Byung-ho, PhD (Wisconsin-Madison)Email:[email protected]

ResearchInterests:1.Plantcellbiology2.3Delectronmicroscopy

Kwan Kin-Ming, PhD (HK)Email:[email protected]

ResearchInterests:1.Geneticmanipulationbytransgenic

andgeneknockouttechnology2.Studyoforganogenesisand

tumorigensis3.Mammalianneuraldevelopment4.Stemcellresearch

Kang, Byung-ho, PhD (Wisconsin-Madison)

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Kwan Hoi-Shan, PhD (UC Davis)Email:[email protected]

ResearchInterests:1.Genomicsandfunctionalgenomics2.Foodsafetyandauthentication3.Microbiology,molecularbiology andbiotechnology4.MolecularanalysisofChinesemedicine andfood

Ang Put Jr., PhD (Br. Col.)Email:[email protected]

ResearchInterests:1.Coralandcoralreefbiology,ecology

andecophysiology2.Seaweedecology,ecophysiology,

phylogeographyandapplications3.Environmentalandfunctional

responsesofmarineecosystems

He Jun-Xian, DS (Lanzhou)Email:[email protected]

ResearchInterests:1.Plantdevelopmentandsignal

transduction2.Functionalgenomicsandsignaling

mechanismsofplantstressresistance3.Improvementofcropyieldand qualityusingmolecularbiotechnologies

Hui Ho-Lam Jerome, DPhil (Oxon)Email:[email protected]

ResearchInterests:1.Organismalbiology/Evodevo2.MicroRNAsinanimal developmentalbiologyandevolution3.Homeoboxgenesregulationand

evolutioninanimals4.Invertebratesendocrinology,

reproductionandbiotechnology5.Genomicsandtranscriptomics

Luo Haiwei, PhD (South Carolina)Email:[email protected]

ResearchInterests:1.Molecularevolutionofmarine

bacteriaandarchaea2.Microbialgenomics3.Ecologicalandevolutionarybioinformatics

Ngo Chi-Ki Jacky, PhD (UC San Diego)Email:[email protected]

ResearchInterests:1.Structure-functionstudiesof

proteinsregulatingpre-mRNAsplicing2.Therolesofsplicingkinasesin

variouscancersandviralinfections3.Molecularbasisofinteractions

betweenkinasesandtheirsubstrates4.Structure-functionstudiesofcancer-relatedproteases

Wong Wing-Tak, Jack, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Vascularandmetabolicbiology2.Stemcellbiology3.Cardiovascularregeneration

Zhong Silin Steven, PhD (Nottingham)Email:[email protected]

ResearchInterests:1.Geneticsandepi-geneticsinplant

development2.Therolesoftranscriptionfactorin

hormonesignaling3.Sequencingtechnologyand

computationalbiology

Zhuang Xiaohong, PhD (CUHK)Email:[email protected]

ResearchInterests:1.PlantCellandMolecularBiology2.AutophagosomeBiogenesisand

AutophagyFunctioninPlants3.MembraneandProteinTrafficking

inPlantCells

.Ecologicalandevolutionarybioinformatics

.Coralandcoralreefbiology,ecology

developmentalbiologyandevolution

mechanismsofplantstressresistance

Lau Kwok-Fai, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Molecularneuroscience2.Molecularpathogenesisof neurodegeneration

Lee Sau-Tuen Susanna, PhD (Cornell)Email:[email protected]

ResearchInterests:1.NuclearreceptorPPARinhealth

anddiseases2.Phytochemicalsastherapeutic

targetsofmetabolicdiseases3.Transgenicanimalsfordisease

models

Leung Lai-Kwok, PhD (KentuckyDirector,FoodandNutritionalSciencesProgrammeEmail:[email protected]

ResearchInterests:1.Toxicologyandpharmacologyof

foodchemicals

Ngai Sai-Ming, PhD (Alta.)Email:[email protected]

ResearchInterests:1.Bioinformaticsandproteomics2.Protein/peptidestructuraland functionalstudies3.Researchanddevelopmenton modernChinesemedicine

Tsang Suk-Ying, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Stemcellbiology2.Derivativesofhumanembryonic stemcellsfortherapeuticpurposes3.Ionchannelsandcardiovascular physiology

Chen Li-yuan, PhD (East Anglia)Email:[email protected]

ResearchInterests:1.PlantE3ligases2.Stemcellsexpressedproteins

inplants3.Planthormonesignalpathways

Koon Chun, Alex, PhD (Mass.)AssociateDirector,LaboratoryofDrosophilaResearchEmail:[email protected]

ResearchInterests:1.Synapticplasticity2.Neurodegenerativediseases3.Neurobiology4.Developemtalbiology

Lee Ming-Ming Marianne, PhD (Ohio State)Email:[email protected]

ResearchInterests:1.Protein2.Proteindelivery3.Chemicalbiology

Qin Jing, PhD (HKU)Email:[email protected]

ResearchInterests:1.Bioinformatics2.Integrativeomicsapproachesfor

generegulationstudies3.Generegulatorynetworks4.Marinegenomics5.Stemcellandcancermulti-omics

Research Assistant Professors

Research Professor

Research Associate Professor

Assistant Professors

proteinsregulatingpre-mRNAsplicing

Zhong Silin Steven, PhD (Nottingham)

15 16

.MolecularanalysisofChinesemedicine

AssociateDirector,Laboratoryof

| SCHOOL OF LIFE SCIENCES

Chow Cheung-Ming Cherry, PhD (Oxford)Email:[email protected]

ResearchInterests:1.Plantcellbiology2.Membranetrafficking3.Nitrogenmetabolisminplants

Lo Fai-Hang, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Molecularcellbiology2.Cancerresearch3.Naturalproductresearch4.Lifescienceresearchandeducation methodologies

Ngai Hung-Kui, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Proteinbiochemistry2.Scienceeducation

Pang Kok-Shuen Iris, PhD (Yale)Email:[email protected]

ResearchInterests:1.Immunology2.Immunedefenseagainstviruses3.Commensalbacteriaandmucosal

immunity

Siow Lam Nina, PhD (HKUST)Email:[email protected]

ResearchInterests:1.Molecularandcellularneuroscience2.Cellsignalingandgeneregulation

Yam Kwan-Mei, MPhil (CUHK)Email:[email protected]

ResearchInterests:1.Molecularbiology2.Endocrinology3.Popularsciencepromotion4.Learningandteachingmethodologies

Chu Kin-Kan Astley, MPhil (CUHK)Email:[email protected]

ResearchInterests:1.Chemicalandphysicalanalyses

offoodmaterials2.Foodprocessingtechnology3.Foodproductdevelopment4.Molecularmarkerforfood authentication

Chui Pui Yi, Apple, PhD (CUHK)Email:[email protected]

ResearchInterests:1.Reproductiveandlarvalecology

ofcorals2.Coralrecruitmentdynamics3.Restorationecologyofcoralreefs

Yip Pui-Sze Peggy, MPH(BenedictineUniversity),RegisteredDietitian(USA)Email:[email protected]

ResearchInterests:1.Nutritionpromotion2.Publichealthandcommunity nutrition

Lecturers

Assistant Lecturers

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ExcellentResearchExcellentResearch

Senior Lecturer

Chiu Chi-Ming Lawrence, PhD (HKU)Email:[email protected]

ResearchInterests:1.Cellsignalinginapoptosis2.Cancerchemopreventionand chemotherapywithnatural

productstargetingthemolecularpathwaysincarcinogenesis

3.Applicationsofflowcytometry

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Hope for Patients withSpinocerebellar AtaxiaSpinocerebellarataxias(SCAs)refertoagroupofgeneticdiseasesthatcauseprogressivedeteriorationof the nervous system, particularly the cerebellum (referred to as ‘small brain’), and are, at present,consideredtobeincurable.Sufferersgraduallylosethefinemotorfunctionsoftheirbodiesandhavedifficultymaintainingbalanceorcoordinatingdailymovements.

Breaking News

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Innovative Platform for Food Authentication

Supermarketsmislabeledoilfishfiletascodfishfilet.Storesclaimedwhelkpiecesasabaloneslides.‘Fraudulentsubstitutions’ishotinthecity.TheydamagetheconfidenceofbothlocalsandtouristsinfoodproductsinHongKong.

The Innovative and Technology Commission of the HongKong Government funded a HK$3 million project ‘First-StageDevelopmentofPlatformforAuthenticationofDriedSeafoodandTonicFoodProducts’.TheleaderoftheprojectisProfessorKwanHoiShan,DirectoroftheFoodResearchCentreatCUHK.Theprojectaimstodevelopadatabaseandplatformwithmorphologicaldataand DNA sequences of common dried seafood and tonic foodproducts in Hong Kong. This platform enables the government,

local industry, and testing laboratories to monitor food products withDNAsequencemarkers.ThesecondtargetoftheprojectistodeveloparapidDNA-baseddiagnostickit forspeciesauthentication.Laboratoriescan quickly distinguish genuine products from the fake ones with thedatabaseandthekit.

Withtheseefficientqualityassurancecontrols,mislabelingandfraudulentsubstitutioninthelocalmarketscanbecontrolled.Theprojectwillcontributetofoodsafetyandenhancethereputationofthelocalfoodmarket.

Professor Kwan received a Bronze Bauhinia Star (BBS) of 2012for his meritorious public and community service, particularly hiscontributiontopromotingfoodsafetyandqualityassurance.

Professor Edwin Chan and histeam, consisting of biochemists,bioinformaticians, cell biologists,chemical pathologist, medicalgeneticists, neurologists andradiologist, embarked on a cross-disciplinary study with the aim ofunveiling the underlying cause of afamilialformofSCAidentifiedinthelocal population. With a concertedexperimental and bioinformaticeffort,theresearchersfinallyconfinedthe SCA mutation to the coiled-coildomain containing 88C (CCDC88C)gene. Thisnewlydiscovered formofSCAhasbeenrecognizedas ‘SCA40’.Thisworkwaspublished inJournalofMedicalGenetics,aleadinginternationalpeer-reviewedjournalinhumangenetics,in2014.ThisisthefirsttimethatresearchersfromHongKonghaveidentifiedanovelgenemutationthatleadstoSCA.TheHumanGenomeOrganizationGeneNomenclatureCommittee,aninfluentialinternationalorganizationformedbyscientistswhostudyhumangenetics,recentlyapprovedtheuseof‘SCA40’todescribethisnewtypeofSCA.ThisimportantfindinghasputHongKongontheworldmapofSCAresearch,andalsoshednewlightonfindingtherapeuticdirections.

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New Way to Battle Stomach Ulcers and CancerHalfofthehumanpopulationcarriesHelicobacter pylori,theonlyknownbacteriumthatsurvivesintheextremeacidicenvironmentinsidethestomach.Thisbacteriumdamagesthemucouscoatingofthegutafterwhichthestomachacideatsawaythesensitiveorgan lining resulting in peptic ulcers. The infection by thisbacterium is also well documented to be a high risk factor ofstomach cancer. Despite the effective mean with high efficacyof using antibiotics to battle with this bacterium, claims ofantibiotic-resistanceovertheyearshaveurgedthedevelopmentfornewtherapies.

‘Thekey to thesurvivalofHelicobacter pylori in theacidicbath in thehumanstomach is itsuseofanenzymecalledurease toneutralizegastricacid’, saidProfessorWongKam-Boof theCentre forProteinScience and Crystallography, School of Life Sciences. Urease requires two nickel ions to be functional.ProfessorWongandhisresearchteamdiscoveredthat,usingX-raycrystallographytovisualizeproteinswithatomicresolution,theassemblyoftheureasewiththenickelionsinvolvesfourhelperproteins:UreE,UreF,UreGandUreH.Theyfurtherrevealedthatdisruptingtheformationofthehelperproteincomplexforbidsthechannelingofthetwonickelionsinplaceandthusinhibitsthesynthesisoftheactiveureasethatisessentialtosurvival.

Theseconspicuousresultshavebeenreleasedlatelyas‘PaperoftheWeek’inJournalofBiologicalChemistry.ProfessorWongsaid,‘Withabetterunderstandingonhowthemolecularmachineisassembled,wecannowproceedtostudywaysthatdissembleit.AsactiveureaseisthekeytothesurvivalofHelicobacter pylori,newdrugsdesignedto target thiscomplexmaywellbeanovelandviablestrategy toeradicatethepathogen.’TheteamisnowdesigningdrugstoinhibitassemblyofthismolecularmachinethatkeepsHelicobacter pylorialiveinhumanstomach.

Breaking News

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The Story Inside and Behind the Soybean Genome

Genomic differences between wild and cultivated soybeans(Photo from Prof. Lam Hon-Ming)

Soybean,firstdomesticatedinChina,isthethirdmostimportantcashcropintheinternationaltrademarket. It istheNo.1sourceof vegetable protein, the leading source of edible oils as wellas a source of biodiesel. In addition, its high symbiotic nitrogenfixingcapacity isenvironmentally importantas itscultivationcannaturallyreplenishsoilnutrients.

Currently,morethantwo-thirdofthesoybeanconsumedinChinais imported. In2013, total importvalueofsoybeanbyChinahadrisentoarecordhighofUS$40billion,mostlyfromtheUSA,Braziland Argentina. However, due to the reduction of arable landsandfreshwaterresourcesinChinaandtheworld,theproductionof soybeans could not meet the its growing demand. Adverseenvironments like salinity also pose severe threat to agriculturalproductivity. Production of stress tolerant soybeans enables abetter use of marginal and low-fertility lands, and hence couldpromotesustainableagriculture.

Prof.LamHon-Ming,DirectoroftheCenterforSoybeanResearch(CSR),hasbeenworkingontheidentificationofstresstolerancegenesinsoybeanformorethan10years.In2010,Prof.LampublishedacoverarticleintherenownedscientificjournalNatureGenetics,reportingthedecodingof31wildandcultivatedsoybeangenomesthatrevealedamuchhigherbiodiversityinwildsoybeans.In2014,histeam has successfully identified and cloned a major salt tolerance gene fromwildsoybeans.ThisfindingwasrecentlypublishedinNatureCommunications,amulti-disciplinaryscientificjournalrankedjustafterNatureandScience.Itisamilestoneinthemassproductionofhighqualitysalttolerantsoybeans,astagereachedwhichwilleventuallybenefitagricultureinChinaandworldwide.

Prof.LamisnowworkingwithsoybeanbreedersinChinatoproducesalinityanddrought tolerantsoybeansthatcanbegrownonsalineand/orarid lands,vianon-GMmethods.Underhis leadership,CSRalsoholdsinternationalsoybeansymposium for researchers worldwide to facilitate international academicexchanges.

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FREE1: A Magic Plant Protein

Left to right: Cui, Gao, Jiang, Luo and Zeng.

Left to right: Gao, Jiang, and Zhuang.

Cellisthebasicunitoflife,whiletheorganellesinsidethecellaretheessential‘organs’oftheplant.Eachcellcontainsmanydifferentkindsoforganelles,whileorganelletypecomprisesdifferentproteinstoperformtheirspecificfunctionsthatcontroltheplantgrowthanddevelopment.

Breaking News

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iGEM – Gold Medal StorySyntheticbiology,arapidlyemergingfieldthatappliesabstractionand other important engineering concepts to biological science,has taken the undergraduate science and engineering educationby storm. The annual iGEM competition has quickly become themajorevent thatencouragesundergraduatestudentworldwide tospearheadinsyntheticbiologyresearch.

OuriGEMteamsconsistmainlybutnotlimitedtostudentsfromtheFacultyofScienceandEngineering.Weworktogetherusingsyntheticbiologyexperimentstodeveloptheir“bio-bricks”,thestandardizedDNApartstailor-madefordifferentspecifictasks,andcharacterizethemsystemicallyandscientifically,wealsoneedtoexplaintheirprojectstoothernon-sciencestudentsandrecentlytosecondaryschoolpupilsandthegeneralpublic.Since the iGEMgamesare internationalgames,weareable tomakecontactswith theirpeers fromuniversitiesoverseasviatheInternetandinthevirtualcompetitionduringtheiGEMJamborees.Thegamesalso

Professor Jiang’s research team has been workingon the underlying mechanisms of protein transport,organellebiogenesisand function inplantcells for15years at CUHK. They have recently discovered a newplant-specific protein (termed FREE1) playing multiplefunctional roles in regulating protein trafficking,organellebiogenesisandfunctioninplants.FREE1wasshownto1)Regulatethetraffickingofvacuolarproteins,2) Control the formation of intraluminal vesicles ofmultivesicular body (MVB), 3) Regulate the vacuolebiogenesis and 4) Mediate vacuole-autophagosomefusion and degradation during autophagy in plants.Since vacuole controls many important aspects ofcropphysiologyincludingseedgermination,pathogendefense,andgrowthundernutrient-limitingconditions,knowledge on the underlying mechanisms of vacuolebiogenesis and degradation will provide new tools forcropimprovementandplantbiotechnology.

These findings, shedding new light on the molecularmechanismsofproteintransport,organellebiogenesisand function in plants, have been published recentlyin two international journals: the Current Biology in2014andtheProceedingsof theNationalAcademyofSciences (PNAS) in 2015. Major contributors of thiswork include Drs. GAO Caiji, ZHUANG Xiaohong, CUIYong,LUOMingandMr.ZENGYunglin.

Previous iGEM projects of Hong Kong_CUHK and their achievements

Year Team Name Specifi c Project Achievements

2010 Bioencryption Using bacterial DNA to store encrypted World Jamboree Gold Medal information

2011 ChloriColight Using light-inducible halorhodopsin Gold Medal, best bio-brick, to transport chloride ion best bio-brick measurement, advanced to world jamboree

2012 Light of No Return Using light to attract bacteria to move by a Gold Medal, advanced to light-sensitive protein linked to a signaling world jamboree pathway to stimulate cell motility

2013 Switch off PAHs Using enzymes to degrade benzo-a-pyrene Silver Medal, advanced to or other polycyclic aromatic hydrocarbons world jamboree

2014 ABCDE, AzotoBacter Developed a protein expression system in Gold Medal obtained in vinelandaii Cluster- Azotobacter with genome recombination World Jamboree transformable Deoxygenated gene transfer cluster mechanism protein Expression

2015 Magnetosome Forming An expression system for the biosynthesis Gold Medal obtained in Azotobacter vinelandii of magnetosomes - prokaryotic intracellular World Jamboree organelles with magnetic properties - in Azotobacter for biotechnology applications

putemphasisonpresentationsinoralformat,posterformat,andtheuseofwikipages.

Joiningsuchcompetitioncouldprovideuswithopportunitiestobeatthefrontrowseattolearnthelatestdevelopmentof researchfieldandnewtechniquesoutsideof theclassroom.Most importantly,wealsolearnhowtoworktogetherandinteractwiththeirpeersattopuniversitiesaroundtheworld.Since2010,wehaveobtained4goldawards,1silveraward,andobtainedBestNewBio-BrickPart(Natural),BestBio-BrickMeasurementApproach,in2011AsiaJamboree(Table1).Ourteamshavehadmanyexposurestothegeneralpublicandmassmediathroughdifferentchannels.

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Academic Honorees and AwardeesAcademician of the Chinese Academy of Engineering and the International Eurasian Academy of Sciences

Professor SUN Sai-Ming SamuelProfessorSun is theResearchProfessorofBiology.He joined theUniversity in1995andwasChairoftheDepartmentofBiologyfrom1996to2004aswellastheFoundingDirector of the Molecular Biotechnology Programme from 1998 to 1999. He hasalso been the Director/Coordinator of the UGC-AoE Centre for Plant and AgriculturalBiotechnology(formerasPlantandFungalBiotechnologyCentre)since2000,Director

ofInstituteofPlantMolecularBiologyandAgriculturalBiotechnologysince2006,DirectorofStateKeyLabofAgrobiotechnology(CUHK)since2008,andMasterofS.H.HoCollegesince2009.

ProfessorSun’sresearchinterestsencompassanumberofareassuchasplantgeneisolation,characterization,transfer,expression,andregulation;plantbioreactors;aswellasricequality improvementandfunctionalgenomics.ProfessorSun iscreditedas thescientistwhofirstclonedaplantgene,discoveredplantgeneinterveningsequences,andenhancedanessentialaminoacidinplantthroughbiotechnologicalapproach.

Croucher Senior Research Fellowship

Professor JIANG LiwenDr.JiangjoinedCUHKBiologyasanAssistantProfessorin2000andwaspromotedasProfessorin2007.ProfessorJiangiscurrentlyChoh-MingLiProfessorofLifeSciencesofSchoolofLifeSciencesandDirectorofRGC-AoECentreforOrganelleBiogenesisandFunction,aswellasDirectorofCentreforCellandDevelopmentalBiology. Professor Jiang’s research team has been working on the underlyingmechanismsofprotein transport,organellebiogenesisand function inplantsfor15yearsatCUHK,andhasbeeninternationallyrecognizedasaleadinggroupinthefield.ProfessorJiangreceivednumerousawardsforteachingandresearchachievements,includingCUHKScienceFacultyExemplaryTeachingAward2008,CUHKResearchExcellenceAwardtwice(2006-07&2009-10),CroucherSenior Research Fellowship twice (2009-10 & 2015-16), Ministry of Education (MOE) Higher EducationOutstandingScientificResearchOutputAwardstwice(2009&2013),OutstandingFellowoftheFacultyofScience(2013)andChoh-MingLiProfessorshipofLifeSciences(2014).GraduatestudentsfromProfessorJiang’slabhavealsoreceivedmanyprestigiousawards,includingCUHKYoungScholarsDissertationAward(twice),PostgraduateResearchOutputAward(fourtimes),KeystoneSymposiumScholarship(twice)andHumanFrontierScienceProgramLong-TermFellows(twice).

As PI/PC, Professor Jiang has received competitive research grants worth over HK$70 million from theResearch Grants Council of Hong Kong, the Croucher Foundation and other important funding bodies.Professor Jiang has also served as editorial board member of several international journals, includingThe Plant Cell, Molecular Plant, BMC Plant Biology, Protoplasma, and Journal of Genetics and Genomics.

Breaking News

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Research Grant Council (RGC)-funded Collaborative Research Fund

Inthelastthreeyears,theSchoolofLifeSciencesreceivedboththeAoEandCRFfundingfromRGCtobuilduponourexistingstrengthsanddevelop them intoAreasofExcellence (AoE)and to fundprojectswithsignificantpotentialtodevelopintoanareaofstrength.

AoE Project:

Professor Liwen JiangandhisteamreceivedanAoEgrantofHK$47.25MtoestablishtheCenterofOrganelleBiogenesisandFunctionbeginninginJanuary2014.

CRF Project:

Professor Liwen JiangandhiscollaboratorswereawardedHK$7.36Mfor“EXPO(Exocyst-positiveOrganelle): Dynamics, Biogenesis and Functions in Plants”. Professor Jiang has just been awardedHK$8.36Mfor“EXPOandAutophagosomeinPlants”.

Professor Hon-Ming Lam and his collaborators were funded HK$6.99M for “Genomic andMolecularStudiesofaSalinityToleranceLocusintheWildSoybeanGenome”.

Professor Edwin Chan was granted HK$7M for his project titled “Targeting RNA and ProteinToxicitiesofPolyglutamineDiseasesUsingPeptidylicInhibitors”.

Professor KH ChuwasawardedHK$7.2Mforhisproject“MarineGenomics:CrustaceanEvolutionandAquaculture”

Other Research Awards

Research Excellence Award

CUHK Young Researcher Award

Year Awardees 2006-2007 ProfessorJiangLiwen 2007-2008 ProfessorChuKa-Hou 2008-2009 ProfessorChenZhen-Yu 2009-2010 ProfessorJiangLiwen 2012-2013 ProfessorLamHon-Ming

Year Awardees 2008-2009 ProfessorKwanKin-Ming 2009-2010 ProfessorChanHo-YinEdwin

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Research in the SchoolTheSchoolofLifeSciencesengagesactivelyinawidearrayofresearchareas.Theyvaryfromassmallasamoleculetoaslargeasahabitat.

Cell BiologyThiscoversawiderangeofinterdisciplinaryareasinlifesciencesthatexplainthemolecular and cellular organization, and how the signaling pathway regulatescellularfunction.Majortopicsincludesignaltransduction,cellfate,neuroscience,stemcellbiology,andcancercellbiology.

Molecular mechanisms of protein trafficking in the plant secretary andendocyticpathwaysprovidehintsforusingplantsasbioreactorsforproducingpharmaceuticals.

Recent development of stem cell research focuses on the basic biology andbiomedical application of embryonic stem cells that aim to identify possiblestrategiesforclinicaluses.

Cancer cells were discovered to be capable of recovering after exposure toa chemical cocktail that triggers programmed cell death. This finding couldpotentiallyhelpthedevelopmentofnew,moreeffectiveanti-cancerdrugs.

Neuroscience is the biology of nervous system, which allows us to sense and respond to the externalenvironment. Our neuroscience research actively investigates the pain hypersensitivity, neuronaldifferentiation,andthepathogenesisofnervoussystemdiseases,forinstance,Alzheimer’sandParkinson’sDiseases.

Ecology and Environmental ScienceOneofourresearchareasisinthedisciplineofwildlifeconservationandhabitatrestoration.Analysesofecosystemfunctioning,bioindicatorassemblages,andmicrobiologicalstatusarethekeyattributesofthedesirableecologicalchangesintermsoftheecosystemintegrityandhealth,whichareofprimaryconcernintheecologicalrestoration.Wealsoinvestigatevegetationcompositionandecologicalsuccessiononfly-ashlagoonsandusedmunicipallandfillsitesforbetterhabitatrestoration.

Enzymesfromfungiandmicroorganismsarestudiedforthebioremediationofsitespollutedbytoxicorganicmatters.Wealsostudythecontaminationsofmetalsandtraceorganicsinthecoastalareasandinlandwaters.

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Marine ScienceA number of nuclear protein-coding genes are used as DNA markersfor resolving the phylogenetic relationships among the decapodscrustaceanssuchasshrimps,lobstersandcrabs.

Thestudiesofdolphin,coralcommunities,andseaweedareunderwayinlocalmarineparks.Impactsofclimatechangeonmarineecosystemsarealsoofourconcerns.

Food & Nutritional SciencesNutritive food ingredients, like lipids and dietary fibers, and non-nutritivechemicals isolated from plant foods are investigated for their potentialbenefitsinpreventionofchronicdiseasedevelopment.

Thepalatabilityoffooddependsonoursensualperception.Keyfoodchemicalingredientsinteractingwithoursensoryreceptorareinvestigated.

Totacklediseasesthathavenotyetbeencuredbymodernmedicine,severalmembersintheSchoolareworkingonfunctionalfoodsandnutraceuticals.The neurological, anti-tumor, and immunomodulatory effects of the activecompoundsisolatedfromtraditionalChinesemedicinesandfunctionalfoodsareexaminedatgeneandproteinlevels,usingpathwayguided,genomicandproteomicapproaches.

Genomics & BioinformaticsThe Human Genome Project has brought enormoustechnological breakthroughs in sequencing technologythat give rise to a new area of research focusing onthe sequence, structural, and functional analysis ofthe genome of all living organisms. The importance ofgenomics isbestexemplifiedduringtheSARSoutbreakin 2003. CUHK researchers deciphered the SARS-coronavirus genome isolated from the patients, andinvestigatehowitmutatesfromthestaininpalmcivets.A number of professors in our School specialize indifferentaspectsofgenomicresearchsuchasevolution,population genetics and epigenetics, in a wide-rangeof living organisms with particular strengths in human,crustacean,andplantgenomics.

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Plant & Agricultural ScienceAchieved international excellence andobtained the official approval from TheMinistry of Science and Technology of P.R.China, SLS members established the State Key Laboratory (SKL) of Agrobiotechnology,in partnership with the prestigious ChinaAgricultural University in 2008. This SKL,comprised 16 principal investigators fromCUHK and 5 associate members from other

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ToxicologyTheresearchof toxicologyandhealthcentreson livermetabolismanddetoxificationenzymesofdrugsandenvironmentaltoxicants,chemicalcarcinogenesis,andthedevelopmentofbiomarkersofeffectsfromchemicaltoxicants.

Research Institutes and Centres�CentreofPlantMolecularBiologyandAgriculturalBiotechnology�CentreforCellandDevelopmentalBiology�CentreforProteinScienceandCrystallography�FoodResearchCentre�SimonFSLiMarineScienceLaboratory

Effects of environmental pollutants, such asmetals,pesticides,and traceorganicson livermetabolism of fish and rats are investigated.Sophisticated techniques involved in thetoxicology research include the differentialgene expression and proteomic studies,molecular toxicologicalapproachwith theuseofgenecloningandDNAarrayaswellastheuseof enzyme markers or reporter gene systemsfor the evaluations of potential health risksof the environmental contaminants includingendocrinedisruptors.Bothmammalianmodelsand fish models are being used for toxicityassessments.

NormalSlight deformity: curved backbone

Severe deformity: curved backbone and tail

Deformity observed in zebrafi sh larvae exposed to Brominated Diphenyl Ether (BDE)-47

Protein ScienceIn this post-genomic era, protein structure-function study is of majorimportance in understanding the molecular basis of cellular pathwaysand developing therapeutic targets. Our ongoing research projects focuson proteins in cellular signaling and biomedical science, pathogenicmicroorganisms,andareofbiotechnologicalsignificance.

Developmental BiologyHow can a single cell (fertilized egg) develop into amulticellular organism with specialized structures andorgans? This question also becomes a very importantmedicalquestion.

Anewbornmaypossesssometragicabnormalitywhentheembryodevelopmentgoeswrongasshowninthefiguresassomegenesaremutatedbygeneticengineeringtechnology.

Theknowledgeofnormaldevelopmentisthebaseforunderstandingabnormaldevelopmentaldiseases.

Thisareaofstudyismadepossiblebytheadvancedmolecularbiology,cellbiology,andgeneticengineeringtechnology.Themammalianembryonicdevelopmentalprocessisstudiedwithmouseasthemodelorganism.

The SKL team and the researchers from the member laboratories at the SKL 2014 Annual Meeting. The current director and deputy director are Prof. Jianhua Zhang and Prof. Hon-Ming Lam (front row, 7th and 9th from left, respectively).

localUniversities,hasreceivedasupporttotalled$19M(2011-2016)fromtheInnovationandTechnologyCommission.This national-level laboratory has a mission to up-scale China’s agricultural technology totheworldfrontierforincreasingagriculturalproductivity,safeguardingfoodsecurityinChina,improvingpeople’snutritionandpromotingcooperationbetweenChinaandHongKongonscientificadvancement.Prioritizedresearchareasincludethedevelopmentofstresstolerant,high-quantity,high-qualityandhighvalue-added crops via the application of state-of-the-art technologies such as genomics, proteomics,metabolomicsandrecombinantDNAapproaches.

SCHOOL OF LIFE SCIENCES || Life Science Programme

AmpleOpportunities

AmpleOpportunities

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SMARTThe new Young Scientist Mentorship And Research Training (SMART) Programme specifically offers adistinguishedresearchexperiencetofirstyearstudents.ThroughindividualguidancefromProfessorsinresearch laboratories, students are able to ignite their inquisitiveness in scientific research at the verybeginningoftheuniversityjourney.Besides,theymayalsoreceiveupto$3300asrewardsforworkingintheresearchlaboratory.

DREAMThe Dedicated Research Exchange And Mentorship (DREAM)Programmeprovidespreciousopportunitiesforourstudentstoexposetothefrontiersofbiologicalresearches.Ourstudentsfirstparticipateinacoachingprogramme,andlearnthebasictechniquesandbackgroundinformationrelatedtotheprojectfromalocalsupervisorintheSchool.During summer, as sponsored by the School, they travel abroad andconduct research projects in foreign laboratories or corporations.Participating institutions and corporations in 2015 include UniversityofCaliforniaatDavis,InstituteofMolecularBiology,AcademiaSinica,andtheLawOfficesofAlbertWai-KitChan,UniversityofTübingen,UniversityofCaliforniaofRiverside,UniversityofOklahoma,BrockUniversity,InstituteofBiologicalChemistryandBiodiversityResearchCenter,AcademiaSinica,etc.

Internship, Scholarship and other opportunities

BBSATheBerkeleyBiosciencesStudyAbroad(BBSA)ProgrammeisnewlyintroducedtoenableupperyearstudentsofourSchooltospendasemesterinUCBerkeley.Theycantake12unitsofupperlevelIntegrativeBiologyand Molecular & Cell Biology courses thereand the credits can be transferred back toCUHKtofulfilltheirgraduationrequirements.SelectedstudentswillbeawardedsubsidiesfortuitionfeeinUCBerkeley.

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University Student Sponsorship Programme

“ThankstotheUniversityandOceanParkConservationFoundation,wewenttoBohol,thePhilippinesfora10-daycetaceansurvey.Duringthe survey, the Pilipino cetacean experts led us to the sea alonga designated line transect. On the boat, three members took turneveryhourtoactivelysearchforthesignsofdolphinandwhalewithbinocular.During2-weeksurvey,wespottedcountlessdolphinsandwhales,rangingfromsmallFraser’sDolphintoenormousPilotWhale,and from active Spinner Dolphin to the shy Melon-headed Whales.Besides,10-meterWhaleShark,waterbirds,differentkindsoffishesand numerous marine organisms were also encountered. This tripbroughtustothenatureandtobeface-to-facewiththewildanimalsthatwecanneverexperienceandseeinHongKong!What’smore,itwasavaluablechanceforustoexperiencethethreathumanposedonourbelovedocean.Afterthistrip,wewoulddefinitelybemoreactivelyengagingourselvesintheconservationofourocean!”

2011participants–LamKa-YiuEric(ENSC)andLeGa-Wun(BIOL)

“It is really an unforgettable experience to participate in a birdpopulation research. Sponsored by Ocean Park ConservationFoundation,westayedinaforestofCebu,thePhilippinesfor14daystolookforanendemicendangeredbirdspeciesBlackShamaCopsychuscebuensis.These birds make long melodious call, and they are onlyfound in Cebu with a population of around 3000. During the 14-daystay,welearntbirdringingandradio-telemetry.Infact,whatwelearntmost was to appreciate the nature. A forest contains various typesofvegetation,and ishome fornumerousanimals. It isalways joyfulto live with the forest, the lovely animals and the stunning naturalenvironmentinharmony.”

2010participant–ChowMing-Him(ENSC)

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Good InternationalizationEveryyear,theUniversityattractsexcellentsecondarystudentsbothfromlocalandoverseas.Currently,theUniversityhascloseto2,000internationalstudentsfromcountriesandregions:allovertheworld.TheSchoolofLifeSciencesadmitted232studentsin2015/16.

SCHOOL OF LIFE SCIENCES |

Outstanding Career Prospects

Outstanding Career Prospects

ThediversetrainingbytheSchoolpreparesourgraduatestonotonlyfeatureinareasrelatedtotheirstudies,butalsofindtheirstarringpathsinareasoutsidelifesciences.

Interviews of Alumni

Biology programme at CUHK was my top choice for my undergraduate study. It offered a broadcurriculumaswellasspecialtopicsinlifesciencethatprovidedmeaverygoodfoundationformygraduatestudyinmarinebiologyaswellasthescientificknowledge,training,skillsof logicalandcriticalthinkingformycareerasaSeniorFisheriesOfficerinthegovernment.

1991Alumnus(Biology)-ChowWing-KuenSenior Marine Conservation Officer, Agriculture, Fisheries and Conservation Department of theGovernmentofHKSAR

I would like to say thanks to all my teachers for their guidance, support, and also the researchopportunitiessuchasthesummerresearchprogrammeandtheinternshipprogrammethatpromptedmetoapplytograduateschoolformoreintensegraduateresearchtraining.ThestudyatCUHKnotonlyprovidedmewithaplatformtoacquiretextbookknowledgeofbiochemistry,butmostimportantlyenabledmetoappreciateitsbeautyofthescientificknowledge.BeingaprofessoratCUHKnow,inadditiontofosteringresponsiblestudentsandresearchers,oneofmyanticipatedrolesistomakesurethattheknowledgeofbiochemistryandlifesciencescanreachdifferentstrataofoursociety,andultimatelyeveryonecanapplyscientificknowledgetotheirworkpositionsanddailylives.

1995Alumnus(Biochemistry)–ChanHo-YinEdwinProfessor,SchoolofLifeSciences,CUHKFacultyExemplaryTeachingAwardeeYoungResearcherAwardeeGeneticsSocietyofChinaThirteenthJu-ChiLiAnimalGeneticsPrizewinner

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To me, the program offered broad knowledge of fundamental science and ample opportunities totranslatewhatIhadlearntintopracticalresearchprojects. Interactivelabcourses,groupprojects,presentations, and diverse program activities are features of this program, which allowed us todevelopindependentthinking,teamwork,andeffectivecommunication.Ibelievetheprogramwillcontinuetothriveandfostertalentswhowillshineindifferentfields.

2002Alumna(MolecularBiotechnology)–LamHung-MingAssistantProfessor,UniversityofWashington,SeattleYoungInvestigatorAward,ProstateCancerFoundationCareerDevelopmentAward,PacificNorthwestProstateCancerSPORE,NCI/NIHIdeaDevelopmentAward(NewInvestigator),DepartmentofDefense’

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IamgladthatIchoseFNSCatCUHKasmyundergraduatemajor.Inadditiontothesolidknowledgeon food science and nutrition from the coursework, the soft skills, like trouble-shooting andcommunicationskills,creativity,andpassionbenefitedmycareerdevelopment.Thesummerlabandundergraduatefinalyearresearchprogrammearesomethinginparticulartomentionastheyallowedmetogainearlyexposuretofoodlaboratoryenvironment.

1997 Alumnus(FoodandNutritionalSciences)–LeungArnoldSeniorFoodScientist,theCoca-ColaCompany

Thoughthereisnodirectlinkagebetweenmymajorandmycurrentoccupation,themorein-depthknowledge in biological science, environmental science and geography help my understandingandanalysestowardsissuesrelatedtoenvironmentandlifescience.Thesedefinitelyfacilitatetheformulationofmorethoroughnewsreports.

2000Alumnus(EnvironmentalScience)–PunWai-LamSeniorReporter,TVB

Iamgladthatsome10yearsagoIputCUHKFoodandNutritionalSciencesprogrammeasmyfirstpriorityinmyJUPASform.Notmentioningitsmulti-disciplinarycurriculum(includingfoodscienceandtechnology,nutrition,biochemistry,biologyetc)providedmewithsolidscientificknowledge,theprogrammealsotrainedmewithavarietyofsoftskillsparticularlycriticalthinking,whicharestillveryusefulinmyeverydaywork.Inaddition,theprogrammeofferedalotofgreatlaboratoryresearchopportunities,especiallyfoodtechnologyandproductdevelopmentaswellasfinalyearproject,whichhelpedmetolearneffectivelyinapracticalandfunway!

2003Alumnus(FoodandNutritionalSciences)–MaKa-MingScientificOfficer,FoodandEnvironmentalHygieneDepartment,HKSARGovernment

Thecriticalpieceofmindacquiredfromprojectworkandassignmentwork,comprehensivethinkingand good communication/presentation skills obtained from lab report and project works, andpersistenceandapieceofmindtoservethecommunitylearntfromthefinalyearprojectaresomeof the critical generic skills that were trained by my major programme. These figured me into anenthusiasticterritoryeducatortoinspirestudentsinScienceEducationofthenextgeneration.Ibrokemyschool’s11yearsofrecordwiththehighestcreditratesandfullpassesformyclasses.SomeofmygraduateshavejoinedtheSchoolofLifeSciencesatCUHKintheseseveralyears.

2005Alumnus(Biology)–HoTikShunHead,DepartmentofScience,TheChineseFoundationSecondarySchool

WhenIenteredtheMBTprogrammein1998,Iwascompletelynewtothefieldofmolecularbiotechnology.Ithenprogressivelyacquiredstate-of-the-artmolecularbiotechnologyknowledgethroughamultitudeofways,includinglectures,sitevisits,summerinternship,aswellasbeingastudenthelperinthelaboratoryofwell-establishedscientists.Nowbeingateacherandmolecularvirologistmyself,Iamofferingthesesimilarwaystotrainandnurtureanewgenerationofourfuturescientists.Withoutdoubts,theMBTprogrammewillbeaperfectstageforthosewhoareseekingtodevelopandshineinthegoldenageofbiotechnology.

2001 Alumnus(MolecularBiotechnology)–ChanChi-WaiMartinResearchAssistantProfessorDepartmentofMicrobiology,TheChineseUniversityofHongKong

LookbackthetimewhenIchosemymajoratCUHK,Ibelievedthatfollowingmyownpersonalinterestswouldgiveno regrets tomy life,so Idevoted toScience,andMBTwasmyfirstchoiceas I reallyliketheideaofDNAandgenes.MBTprogramhasgivenmewonderfulUniversitylife,theProfessorsareinspiringandthelabcoursesarepractical,well-equippedmewithscientificknowledge,criticalthinking and laboratory techniques. Final year project has also trained me to be a careful, tough,logicalandoptimisticperson.Aftergraduation,IfurtherstudiedattheCUHKGraduateSchool,andwenttobothCanadaandUSAforaperiodofpost-doctraining.Luckily,nowIgotmyfacultypositionattheMacauUniversityofScienceandTechnology,andhavetheopportunitiestorunmyownlabandresearchprojects.Aftersomanyyears,IamstillveryproudofbeingthefirstyearofMBTgraduatesasithasstartedmyscientificcareerasaScientist,andIbelievedthatIhadmadethebestchoice.

2001 Alumna(MolecularBiotechnology)-LEUNGLaiHan,ElaineAssistantProfessorMacauInstituteforAppliedResearchinMedicineandHealthMacauUniversityofScienceandTechnology

ThecurriculuminFNSCatCUHKisnotonlybeneficialtomycareerbutalsomylife. Theseriesoffoodsafetyandmicrobiologycoursesbuiltupmyknowledge,preparedmewelltowinthejobasaHealthInspectorandgrantedmecompetitiveadvantageinmycareer.Ontheotherhand,thenutritionrelatedonesallowedmeto liveahealthier life though Iwasnot in thatfield.Not tomention, theinspiringandheartfeltwaysofteachingandinteractivelearningenabledmetoseeandthinkfromdifferentangles.AlsothankstotheFNSacademicvisitandexcursionprogramswhichhaveledmyeyesbeyondthelocalityandallowedmetoexchangetheexperiencewithcounterpartsoffoodandnutritionalsciencesinothercountries.

2006Alumnus(FoodandNutritionalSciences)–ChanYun-kwanHealthInspector,FoodandEnvironmentalHygieneDepartmentoftheGovernmentofHKSAR

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| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |39 40

Learninginterestingfactsaboutfoodandnutrition,doinglabs,cookingfornewfoodproducts–IwouldsaystudyingintheFNSprogrammewasoneofthemostenjoyabletimeinmylife.Ithasalsopavedthewayformycareerofbecomingaregistereddietitian.FNSteachingstaffweresupportiveandhelpedmemeetalltheessentialrequirementstoenrollintotheoverseasdieteticsmaster’sprogramme.TheknowledgeacquiredfromtheFNSprogrammewasusefulandpractical,whichenabledmetooftenexcelinthepostgraduatestudyofdietetics.OurFNSdietitianalumniwereveryhelpfultoobysharingtheirexperiencesinoverseasdieteticstudyandreal-lifeworkasalocaldietitian.Iwouldliketotakethisgoodopportunitytosay“thankyou”toyouall.

2006 Alumnus(FoodandNutritionalSciences)–WongSze-ManCandyDietitian,HospitalAuthorityMasterofScienceinNutritionandDietetics,theUniversityofSydneyAccreditedDietitian,HongKongDietitiansAssociationAccreditedPractisingDietitian,DietitiansAssociationofAustralia

Biochemistry

Biology

CellandMolecularBiology

Programmes in the School of Life Sciences

EnvironmentalScience

Food&NutritionalSciences

MolecularBiotechnology

Aftergraduation,Icontinuedmystudyinthefinanceareas,andobtainedmyMasterdegreeinFinanceandtheAdvancedDiplomainProfessionalFinancialPlanning.Iamnowworkingintheareaoffinancialplanningengaginginthewealthandrelationshipmanagement.Financialworldisfullofuncertainties.StrongandindependentlogicalthinkingandscientificmethodIacquiredfrommyundergraduatestudybenefitmyjudgmentindecipheringthereasonandfindingouttheanswersfortheseuncertainties.Iparticularlythanktheinspirationprovidedbymyprogrammeforthescientificandpersonalgrowth.

2007Alumnus(Biology)–MokKai-CheungStevenChiefWealthManagementAdvisor,ConvoyFinancialServicesLimitedSwissPrivilege–FinancialPlanningTop10AwardeeHongKongInstituteofBank–FinancialPlanningCompetitionAwardee

Theprogrammeequippedmewithknowledge,boththeoreticalandpractical,ofcurrentadvancesin the field and skills for conducting research in life sciences.These prepared me well for thestudyofM.Philthatfacilitatedmyjobhuntingintheeducationfieldaftergraduation.ThetrainingalsoallowsmetosharethecurrentdevelopmentinthefieldwithstudentsbothfromtheviewofresearchersaswellaspublichealthwhichishotinLiberalStudies.

2007 Alumnus(Biochemistry)–HoLilianGraduateMaster/Mistress,HolyTrinityCollege

SCHOOL OF LIFE SCIENCES |

BackgroundBiochemistry isabranchofsciencethat investigatesthechemicalcompoundsandprocessesoccurringinlivingorganismsatmolecularlevel.Theknowledgeprocuredfromthestudyinbiochemistryhasfoundextensiveapplicationsinmedicineandbiotechnologythatdrasticallyrevolutionizeourdailylife.

In1971,theUniversityestablishedtheDepartmentofBiochemistry(nowtheBiochemistryprogramme),anditquicklybecameastrongprogrammeinteachingandresearch.ThestudyofBiochemistryintheSchoolcomprisesabroadarrayofscientificdisciplines,includingthechemistryoflifeprocesses,bioinformatics,the metabolism of biomolecules and their regulation, energy transformation, the functions of enzymesandthestructure-functionrelationshipofenzymesandproteins,genomeresearchandgeneticdiseases,heredityandevolution,themechanismsofthenervous,immuneandendocrinesystems,biotechnology,andbiomedicalsciences.

Mission� Toprovideconceptsandmechanismsofbiochemicalprocesses,withemphasisonclinicalandbiomedical

sciences�Toprovidetrainingonthelatestbiochemicaltechnology�Tocultivatetheabilityofcriticalthinking,aproactiveandresponsibleattitudeandefficientcommunication

skillsforhighcompetitivenessinfurtherstudyandinthejobmarket

BIOCHEMISTRY

Curriculum Highlights�Currenttopicsinbiochemistryandmolecularbiologythathavescientific,medicalandsocialsignificance�Self-studymodulesandindependentresearchopportunity

Biochemistry (BCHE)

Study Focus: Elective Areas:� GeneticsandCellBiology � IndependentresearchinBiochemistry

� ProteinandEnzymes � Self-studymodulesinBiochemistry

� BioenergeticsandMetabolism � ClinicalBiochemistry

� MethodsinBiochemistryand � Immunology

MolecularBiology � Endocrinology

� BiomedicalandHealthSciences � Neuroscience

� IndependentResearch � ForensicSciences

� SportSciences

� AdvancedtopicsofferedbySLSprogrammes:

Biology: Microbiology,AnimalPhysiology,HumanGenetics

Cell & Molecular Biology:ProteinTraffickingandFolding,StemCellBiology, CellBiologyofCancerandNeuronalSystem

Environmental Science:BiochemicalToxicology,EnvironmentalHealth Food & Nutritional Sciences: MedicalNutritionTherapy,Nutritionand HumanDevelopment

Molecular Biotechnology:AnimalBiotechnology

� Statistics:Biostatistics

Curriculum

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Career Talks given by Alumni

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Expected learning outcomes

Views of current students

ContactWebsite:www.bch.cuhk.edu.hk/Email:[email protected]:852-3943-6359

ProgrammeDirector:[email protected]

BackgroundBiologyisabroadfieldembracingmanydifferentdisciplines,whichincludethestudyoflivingorganismsfromvirustohuman.Fundamentaltothestudyoflifeisunfoldingbiologicalorganizationatitsmanylevels,from molecular architecture to ecosystem structure. During the past few decades, new discoveries inbiologyhashavebroughtsignificantimpactonthewaywelive.Armedwithexcitingnewresearchmethodsandinformationfromgenomicsofhumanandotherlivingorganisms,biologistsarebeginningtounravelsomeoflife’smostengagingmysteries.

TheDepartmentofBiology,nowtheBiologyProgramme,wasestablishedin1963,andisoneoftheoldestdepartmentsintheUniversity.Indeed,wearethefirstbiologicalsciencesdepartmentinHongKongawardedtheAreaofExcellencebyUniversityGrantsCommittee.Weofferabroadrangeofsubjectsforstudentstochoosefrom,includinggenetics,physiology,plantbiology,zoology,marinebiology,andecology.

Mission�Topreparestudentsforcareersinbiologicalsciencesandrelatedfields� Toprovidestudentswithknowledgeonthelatestdevelopmentsandadvancementsinbiology� To promote excellence in teaching and research in all levels of biological sciences from molecular to

organismalbiology

BIOLOGY

43 44

� Understand the core knowledge in biochemistry coveringbiomolecules,molecularbiology,cellularbiochemistry,metabolism,bioinformatics,proteinsandenzymes

� Gain the knowledge of the latest biochemical technology inclinical biochemistry, immunology, neurosciences, biotechnology,endocrinology,sportandforensicsciences,genomicsandproteomics

�Possess skills in designing experiments to test hypothesis,writingresearchreport,applyingtheirknowledgetodailylife,anddevelopingself-learningcapability

�Becomeall-roundcompetent

ThecurriculumofBiochemistryprogrammecoversdifferentaspectsofbiochemistry.IcanchoosetopicsinwhichIaminterested for in-depth study. There are also abundantopportunities for students to participate in a researchproject. This helps to develop my critical thinking skill.Apart from academic studies, I have also enjoyed thedifferentactivitiesorganizedby theBiochemistrySociety,whichmakemyuniversitylifemoreenjoyableandfruitful.

ChanWai-Wa

Myinterest inclinicalbiochemistryandbiomedicalsciencesgotmetochooseBiochemistryasmymajor.Havingamarvelousteachingteamandmanyinterestingstudytopics,theprogrammeprovidesquality education and numerous research opportunities for us. These help to equip me in manydifferentaspectslikeresearchandcommunicationskills.

WanTsz-Yau

Biochemistry 40th Anniversary High Table Dinner

Studying the stream ecology through fi eld investigation

Appreciating the value of plants in a campus walk

Examining the fl oral structures

Investigating biodiversity at a rocky shore

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Biology (BIOL)

Study Focus: Elective Areas:� Ecology � Microbiology,EvolutionaryBiology,Plant,Marine&AnimalBiology,

� Genetics DevelopmentalBiology,ConservationBiology,Physiology,FieldStudy

� Biodiversity � Advancedtopicsofferedbyotherprogrammes:

� FundamentalsofBiochemistry& Biochemistry:BioenergeticsandMetabolism,MolecularBiology,

CellBiology Immunology,Endocrinology

� FundamentalsinOrganicChemistry, Cell & Molecular Biology: ProteinTraffickingandFolding,StemCellBiology,

Mathematics,andPhysics CellBiologyofCancerandNeuronalSystem

Environmental Science:PollutionandToxicology

Food & Nutritional Sciences:FoodMicrobiology

Molecular Biotechnology:MolecularBiotechnology

Statistics: Biostatistics

Curriculum

Curriculum HighlightsThree recommended packages based on the different combinations of the courses offered by BiologyProgramme:(1)OrganismicBiology;(2)HumanBiology;and(3)BiologyforTeachingCareer.

Expected learning outcomes� Acquirebasicknowledgeinallaspectsofbiologicalsciencesandin-depthunderstandinginatleastone

majorareaofbiology� Developskillsinscientificproblemsolving,statisticsandinformationtechnology� Understandthelatestdevelopmentsandadvancementsinbiology� Appreciatetheimportanceofbiologicalconservationandenvironmentalissues

Views of current students

After finishing my associate degree in Health Studies at HKCC, I joined CUHK due to its diversechoices in life sciences. Finally, I picked Biology as my major because I think Biology is a veryinterestingtopicandtheknowledgeacquiredhelpspreparemyselftofurtherstudyinbiomedicalsciences,suchasmusculoskeletalmedicineandrehabilitation.

YauMan-Ho

TheBiologyProgrammeoffersnumerouscourseswhichcovermany topics inbiologicalsciencesfromtinymicroscopiccells to themacroscopicecosystem,and italsohasstudypackageswhichhelpusplanourcareerpathupongraduation.Inaddition,careertalksareorganizedbytheBiologySocietyannuallyforourbetterunderstandingtowardspossiblejobopportunities.

LeungHill-ToneJessica

ContactWebsite:www.bio.cuhk.edu.hkEmail:[email protected]:852-3943-6249

ProgrammeDirector:[email protected]

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Winter Camp BBQ gathering of students and teachers

Sampling water from the sea

| SCHOOL OF LIFE SCIENCES

BackgroundCell and molecular biology is the foundation of contemporarylife sciences and represents the frontiers of modern biology andbiomedicine.Withthecompletionofgenomeprojectsinhumanandan increasing number of different organisms, the focus of modernbiology is quickly shifting to functional genomics which aims atunderstanding the functions of genes at molecular, cellular, andorganismlevels.

It is in this background that the University proudly launched thenew Cell and Molecular Biology programme in 2008. As the firstprogramme focusing on cell and molecular biology in the region,we target to train superior professionals that fulfill the increasingmanpowerdemandforthecutting-edgeresearchesinthefieldsofcellbiologyandmolecularbiology.Theseadvancedscientificdisciplinesincludestemcellbiology,cancercellbiology,neurobiology,signalingtransduction,anddevelopmentalbiology.

Mission

Cell & Molecular Biology

Curriculum Highlights� STOTcoursesconductedineitherasmallclassor1student-on-1teacherbasis� Intensiveproject-basedlabtraining� Extensivecoverageofcontemporaryandadvancedtopicsincellandmolecularbiologyontopofthe

solidknowledgeinlifesciences

Cell and Molecular Biology (CMBI)

Study Focus: Elective Areas:� ResearchmethodsandScientificcommunication � IndependentresearchinCell&MolecularBiology

� StemCellBiology,CellBiologyofCancerand � AdvancedtopicsofferedbyotherSLSprogrammes:

NeuronalSystem Biology:Physiology,DevelopmentalBiology

� Genomics,Transcriptomics&Metabolomics Biochemistry:Clinicalbiochemistry,Neuroscience,Immunology� ContemporarytopicsinCellBiologyand MolecularBiotechnology:Animal,PlantandMicrobial

MolecularBiology Biotechnology,andGeneticEngineering

FundamentalsinBiochemistryandGenetics � BiomedicalEngineeringofferedbytheFacultyofEngineering

FundamentalsinOrganicChemistry, � Statistics:Biostatistics

Mathematics,andPhysics

Curriculum

� Toprovidethebesteducationandtrainingthatpreparestudentswithprofessionalresearchcompetenceinbiologicalandbiomedicalsciencesaswellasbiotechnology

� Tobecomearegionaleducationcentrewithinternationalrecognitionandapremierresearchhubforcutting-edgeresearchincellandmolecularbiology

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| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Expected learning outcomes� Acquiresolidsubjectknowledgeinthefieldsofcellbiologyandmolecularbiology� Comprehendlaboratoryskillsessentialforaresearchcareer� Possessall-roundcompetence

Views of current students

This one-to-one STOT learning scheme provides studentswith an extraordinary angle to appreciate the wonderfulscientific world. Family-like atmosphere in CMB allowsgood interactions among teachers, staff and students.The project- based CMBI lab courses are fascinating. Notonlythatwelearnttheessentialtechniquesformolecularcloning, we also worked with plant cells and mammaliancellsforourcellbiologyprojects.

MaTsz-ChingCharlotte

Marvelousteachingteam,niceresearchfacility,interestingstudy topics, and constructive career development aresomeofthemanyreasonsthatIwouldrecommendCMBtoyou.Theskillsinwriting,presentation,criticalthinking,andscientificresearchhavewellpreparedmetobeascientifiresearcher.

KwokChun-HoLeo

ContactWebsite:www.cuhk.edu.hk/cmb/Email:[email protected]:852-3943-1361

ProgrammeDirector:[email protected]

BackgroundEnvironmental Science is an integrated science usingthe basic knowledge and skills of applied biochemistry,biologyandchemistrytoassessandresolveenvironmentalproblems. In response to the growing public concernsabout the environmental protection and conservationissues, the University established the EnvironmentalScienceprogrammein1994.

We foster our students with training in ecology,environmental chemistry, pollution control, wastemanagement, biodiversity, conservation, toxicology andhealth,energyresearch,environmentalimpactassessment,andpolicydevelopment.OurbodyoflecturingstaffcomprisesprofessorsfromtheSchoolofLifeSciencesandDepartmentofChemistry,aswellasotherprofessionalsfromrelateddisciplines.Inaddition,ourAdvisoryCommittee,composedofthespecialistsfromtheGovernment,industries,andotheracademicsectors,alsoprovidespreciousadviceoncurricularmatters,thusimprovingtherelevanceofourgraduatestothelocalneedinparticular,andthatofoverseasaswell.

Mission� To provide wide multidisciplinary background in environmental sciences with good communication

skills� Tocultivatehighlevelofcompetenceinscientificunderstandingofenvironmentalissueswithcreative

ideainsolvingenvironmentalproblems� Totrainourstudentswiththeappropriateprofessionaltechniquesinaddressingdifferentenvironmental

issues

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ENVIRONMENTAL Science

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Curriculum Highlights� Electivecourses fromtheDepartmentofGeographyandResource

Management in Faculty of Social Science and the Public HealthProgramme in Faculty of Medicine, such as, Urban EnvironmentalProblems, Ecosystem Restoration and Management, HydrologyandWaterResources,Biostatistics,SoilScience,EnvironmentandHealth,etc.

� ElectivecoursesfromChemistryandEarthSystemScienceinFacultyof Science, and Energy Engineering in Faculty of Engineering, suchas Energy Utilization and Human Behavior, Atmospheric Science,ChemistryinBiofuel,etc.

Expected learning outcomes� Understand the core knowledge covering environmental chemistry,

biologicalconservation,toxicologyandenvironmentalimpacts

� Developtobeanactiveresearcherandprofessionalinvariousaspectsofenvironmentalsciencewithinnovativeideas

� Adapt to fast-changingsocialenvironment tostaycompetitive in jobmarket and be aware of the latest developments in environmentalpolicyandissues

Enviromental Science (ENSC)

Study Focus: Elective Areas:� Ecology � ChemistryinBiofuels

� EnvironmentalChemistry&Instrumentations � ChemicalTreatmentProcesses

� EnvironmentalImpactAssessments � ConservationBiology

� EnvironmentalandBiochemicalToxicology � EnvironmentalBiotechnology

� Internship � EnvironmentalProtection&PollutionControl

� EnvironmentalHealth

� FieldStudy

� HongKongFloraandFauna

� MarineBiology

� MethodsinToxicologicalResearch

� Electivesfromotherprogrammes

Curriculum

Career prospectHalfofourgraduatesdirectlyinvolveinenvironmentalrelatedjobsaftergraduation.Theyworkingovernmentdepartments, consulting firms, green groups, and commercial sectors focusing on various aspects ofenvironmentalissues,fromgreenpurchasing,carbonaudit,toenvironmentalimpactassessmentsandtreemanagement.Othergraduatesbecomepost-graduatestudentsorfindjobsinschoolsasteachers,inthebusinesssectorsasadministratorsormarketingofficers.

Views of current studentsI am a final year student studying environment science. Throughout my three-years university life,myundergraduatecurriculumenablesmeto learnawidevarietyofenvironmentalmanagementandprotectiontopics,Ihavegainedextensiveknowledgeinmystudiesanddevelopedasamulti-dimensionthinker.Ihavefoundanareainwhichmycuriosityandmyabilityaresuitablypaired.Inmyfinalyear,IhavetakenDirectResearchProject forstrengtheningmy laboratoryskillsand independentworkingability. Furthermore, it would be a valuable to have a preliminary experience being a scientist. Thisprogrammeprovidesanumberofelectivecoursesfromotherrelevantdepartment,fieldstudies,aswellasencouragingthedevelopmentofaspiringenvironmentalistsdirectlyinclassroomandlaboratory.

MakChuWa

Iamafirstyearstudent inENSC.Classmatesare friendlyandwilling tohelp in theprogramme.Inthisyear,Ihavelearntbasicknowledgeabouttheenvironmentalproblemsandtheirsolutions,whichareessentialformetoworkintheenvironmentalaspectlateronaftergraduation.

SiuHoi-Ying

ContactWebsite:www.cuhk.edu.hk/ens/Email:[email protected]:852-3943-6294

ProgrammeDirector:[email protected]

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| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |53 54

Food & Nutritional Sciences

BackgroundFoodsafetyandhealthyeatingthatimprovethequalityoflifehavebecomeaneverydaycriticalawareness.Therapidadvanceandexpansionoffood-relatedindustriesfurtherposenewchallengesandresearchopportunitiesinfoodandnutritionalsciences.

In response to the increasing demand of manpower for food science andnutritional studies, the University established the Food and NutritionalSciencesprogrammein1994.Weareintendedforstudentswhoareinterestedinmodernfoodandnutritionalsciences,andtheirdiverseapplicationssuchas

foodsafetyandtoxicology,foodmicrobiology,foodpreservation,foodproductdevelopment,foodanalysis,quality assurance, nutrient metabolism, introductory dietetics, and community nutrition. The specializedtraininginthefieldwithwidescopepreparesourstudentsfortheemploymentintheindustrialandcommercialsectors,ingovernmentandprivatehealthservices,andfoodcateringinstitutesservicesorganizations.

Mission� Toprovidetrainingtostudentsonmodernfoodandnutritionalsciences,withanemphasisonoriental

culturalbackgroundandperspectives

� ToprovideresearchanddevelopmentexpertisethatenhancesandsustainsthecompetitivenessoftheHongKongfoodindustryandhealth/nutritionprofessionsandbusiness.

Curriculum

Food and Nutritional Sciences (FNSC)

Study Focus: Elective Areas:� Nutrition&HumanDevelopment � IndependentresearchinFoodandNutritionalSciences

� FoodChemistry&Analysis � CommunityNutritionandMedicalNutritionalTherapy

NutritionalBiochemistry � FoodTechnologyandProcessing

� GeneralandFoodMicrobiology FoodProductDevelopmentandQualityControl

� FundamentalsofBiochemistry&CellBiology FoodSafetyandToxicology

� FundamentalsinOrganicChemistry, HumanandNutritionalPhysiology

Mathematics,andPhysics AdvancedtopicsofferedbyotherSLSprogrammes:

� Biology:Genetics

� Biochemistry:Immunology,Endocrinology

EnvironmentalScience:EnvironmentalToxicology

MolecularBiotechnology:GeneticEngineering

� Statistics:Biostatistics

Expected learning outcomes� Understand thecoreknowledgeand latest issues in foodandnutritionalsciences thatpromote the

competitivenessofthestudentsinthelabormarket� Acquireabilitiestoaccess,retrieveandcriticallyevaluateinformationrelevanttofoodandnutritional

sciences� Applytheknowledgeoffoodandnutritionalsciencesintoreal-lifepracticalsituations

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |55 56

Views of current studentsThe good reputation and interesting study topics brought meto the CUHK Food and Nutritional Sciences. The contents of themajor courses are good. The knowledge related to food scienceand nutrition well prepares me for future career development.Oneexcellenceaboutthecurriculardesignisthechancestostudydifferenttopicsinlifesciencesbeforeselectingthemajor.

KwokWing-Hang

FoodandNutritionalSciencesprogrammehasanexcellentteamofteachers who are enthusiastic about teaching.They are very kindto offer helping hands. The well being of the students is alwaysprioritized.

YuChi-On

ContactWebsite:www.sls.cuhk.edu.hk/index.php/fnscEmail:[email protected]:852-3943-8137

ProgrammeDirector:[email protected]

BackgroundMolecularbiotechnologyisarevolutionaryareaofscientificdisciplinethat involves the application of gene and protein technology. Thisstate-of-the-art technology has exerted remarkable contributions toagriculturalhealth,environmental,bioenergy,andotherbio-industrialareas. Molecular biotechnology is one of the major driving forcesshapingthedevelopmentofhumansocietyinthe21stcentury.

In view of the current needs of increasing manpower and futureprospects of biotechnology, the University launched the MolecularBiotechnology programme in 1998. We target students who areinterested in genetic engineering, molecular biology, methods inbiochemistry, microbial, plant, and animal biotechnology. Other in-depth knowledge from an array of elective courses covering variousaspectsofcell&developmentalbiology,animalandplantphysiology,immunology and clinical biochemistry, bioinformatic, genomics andproteomics are also provided for students’ selection. In addition, wealso address the business and social implications of biotechnology,such as government policy, management, intellectual property, andethicalandpublicconcerns.

Mission� To provide theoretical and hands-on training to students on the fundamental knowledge, current

development,businessandsocialimplicationsofmolecularbiotechnology� Tocultivatetheabilityoflogicalandcriticalthinking,andscientificcommunications

Molecular Biotechnology

MBT 10th Anniversary Banquet The 10th Anniversary Symposium of the Molecular Biotechnology programme

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Curriculum Highlights� Fundamentalknowledgeinlifesciencewithemphasisonmolecularbiotechnology� Hands-onskillsthroughspeciallydesignedlaboratorycoursesonmethodsinmolecularbiotechnology� In-depthknowledgeinselectedareasofyourchoice.Topicscovervariousaspectsofchallenge’sfields

inbiology&biochemistry� Comprehensive understanding of the business and social implications of biotechnology, such as

governmentpolicy,management,intellectualproperty,andethicalandpublicconcerns

Moleular Biotechnology (MBTE)

Study Focus: Elective Areas:� MolecularBiotechnologyinAnimals,Plants � IndependentresearchinMolecularBiotechnology

andMicroorganisms � AdvancedtopicsofferedbyotherSLSprogrammes:

� Business&SocialAspectsofBiotechnology Biochemistry:ProteinandEnzymes,Bioenergeticsand

� MethodsinMolecularBiotechnology Metabolism,Immunology,ClinicalBiochemistry

� MethodsinBiochemistry Biology:Physiology,DevelopmentalBiology

� Genetics&GeneticEngineering Cell&MolecularBiology:StemCellBiology,CellBiologyof

� CellBiology&DiversityofLife CancerandNeuronalSystem

� Microbiology � Statistics:Biostatistics

� FundamentalsinOrganicChemistry, BiomedicalEngineeringofferedbytheFacultyof

Mathematics,andPhysics Engineering

Curriculum

Visit biotechnology companies Career talk given by alumni

Expected learning outcomes� Gainsolidknowledgeinlifescience,withparticularemphasisontheprinciplesandpotentialapplications

ofmolecularbiotechnologyincludesgeneticengineering,molecularbiology,methodsinbiochemistry,microbialbiotechnology,plantbiotechnologyandanimalbiotechnology

� Acquirehands-onoperationalcapabilityinbasicskillsofmolecularbiotechnology� Understand the business and social implications of biotechnology, such as government policy,

management,intellectualproperty,andethicalandpublicconcerns� Beabletojudgetheprosandconsofvariousapplicationsofmolecularbiotechnologyonhumansociety

andnaturalenvironment� Acquirehands-onoperationalcapabilityinbasicskillsofmolecularbiotechnology� Developcompetitivequalityforfuturecareersinscientificresearchanddevelopment

View of current students

IenrolledtotheUniversityviatheEarlyAdmission Scheme. After the first yearofstudyinlifesciences,Ifoundthatwehad a good chance to know the studytopicsandformatbeforereallychoosingthe preferred major. I have decided tochooseMolecularBiotechnologyformymajor, and it is because its curriculumstrikes an excellent balance betweenbasic science knowledge and technicalskills. In addition, the ample researchchancesandgoodreputationareotherfactorsthatbringmetothisprogramme.

WooTheodosia

ContactWebsite:www.mbt.cuhk.edu.hk/Email:[email protected]:852-3943-6393

ProgrammeDirector:[email protected]

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Graduation

| SCHOOL OF LIFE SCIENCES SCHOOL OF LIFE SCIENCES |

Minimum Admission RequirementsJUPASAdmission� Students who have taken HKDSE and intend to major in one of the six programmes offered by the

SchoolofLifeSciences,i.e.Biochemistry,Biology,CellandMolecularBiology,EnvironmentalScience,FoodandNutritionalSciences,andMolecularBiotechnology,shouldapplytheSCIENCEbroad-basedadmissionscheme(JUPASCode:JS4601,Science).

Theminimumeligibilitytoapplyis4coreand2electivesubjects(4C + 2X or 4C + M1/M2 + 1X),withtheminimumrequirementsforthe4coresubjectsofChineseLanguage,EnglishLanguage,Mathematics,andLiberalStudiesatlevels3322respectively.

JUPAS Catalogue No. / Elective Requirements (X) Remarks

Programme Subject Level

JS4601- AnyONEsubjectfromthefollowing: Level3 BonuspointswouldSCIENCE -Biology beofferedtothe3rd -Chemistry electivesubjectin -Physics CategoryA. -CombinedScience -IntegratedScience -Mathematics(Module1 or 2)

AnyONEsubjectinCategoryA# Level3

59 60

Non-JUPASAdmission� AcquiretheInternationalBaccalaureateDiploma;OR� Obtain good grades in Hong Kong Advanced Level (HKAL) Examination or GCE Advanced Level

ExaminationwithnolessthanthreeAdvancedLevelsubjects;OR� Possessaqualificationwhichqualifiesforuniversityadmissionintheissuingcountry(e.g.SATinUSA,

UEC/STPMinMalaysia,ATARinAustralia,OSSDinCanada);OR� Completedanassociatedegreeorhigherdiploma

MoredetailscanbefoundinthewebpageofOfficeofAdmissionsandFinancialAid.

#Preferredsubjects:Biology,Chemistry,Physics,CombinedScience,Economics,Geography,Informationand CommunicationTechnology,IntegratedScience,Mathematics(Module1or2),andTechnologyandLiving(Food Science&Technology)

GeneralOfficeoftheSchoolofLifeSciencesRoom132,ScienceCentreNorthBlockTel:3943-6122Email:[email protected]:www.cuhk.edu.hk/lifesciences/

Copyright©2016SchoolofLifeSciences,FacultyofScience,TheChineseUniversityofHongKong.AllRightsReserved.

School of Life Sciences | 生命科學學院School of Life Sciences | 生命科學學院

Coverphoto(琴葉紫菀)iskindlyprovided(taken)byDr.DavidLauofCUHK.