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Paliwal et al. World Journal of Pharmacy and Pharmaceutical Sciences
PHYSIOLOGICAL STUDY OFAGNI AND ITS CLINICAL
SIGNIFICANCE
Sweta Paliwal1*,
O. P. Tiwari
2, Gugulothu Ramesh
3 and Shivansh Chandra Sharma
4
1,4
MD (AYU) Scholar Sharir Kriya, 2MD (AYU) HOD Department Sharir Kriya
3MD (AYU) PG Department Sharir Kriya
V.Y.D.S Ayruved Mahavidyalaya Khurja, Bulandshahr.
ABSTRACTS
In Ayurveda Agni has a significant role to maintain body homeostasis,
body functioning, digestion and metabolism in our body. The term
„Agni „is used in the sense of digestion of food and metabolic products.
Agni converts food in the form of biological energy, which is
responsible for all the vital functions of our body. therfore, Ayurveda
considers that dehagni is the cause of life, complexion, strength, health,
nourishment, luster, oja, teja(energy) and prana (life energy). About
the importance of agni, acharya charak has mentioned that after
stoppage of the function of agni, the individual dies, and when the agni
of an individual is samagni, than that person would be absolutely
healthy and would lead a long, happy, healthy life. But, if the agni of aperson is vitiated, the
whole metabolism in his body would be disturbed, resulting in ill health and disease. Hence,
Agni is said to be the base (mool) of life. According to function and site of action Agni is
divided into three types i.e. 1 jatharagni, 5 Bhutagni and 7 Dhatwagni. Jathagni is the most
important one which digest 4 types of food and transform into Rasa and Mala. Vagbhatta says
that root of all diseases is Mandagni and Samagni is for health. Maximum number of diseases
is directly and indirectly related to the improper functioning of agni. So understsnding of
Agni concept is need of Ayurvedic physician to determine the of Agni during during
prescribing drugs. This article shows the physiological study and clinical importance of agni.
INTRODUCTION
In Ayurveda, the term “Agni” is used in the sense of digestion of food and metabolic
products. Agni converts food in the form of energy, which is responsible for all the vital
WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
SJIF Impact Factor 7.632
Volume 11, Issue 6, 119-130 Review Article ISSN 2278 – 4357
*Corresponding Author
Dr. Sweta Paliwal
MD (AYU) Scholar Sharir
Kriya, V.Y.D.S Ayruved
Mahavidyalaya Khurja,
Bulandshahr.
Article Received on
15 April 2022,
Revised on 05 May 2022,
Accepted on 25 May 2022
DOI: 10.20959/wjpps20226-20263
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Paliwal et al. World Journal of Pharmacy and Pharmaceutical Sciences
functions of our body. Therefore, Ayurveda considers that Dehagni is the cause of life,
complexion, strength, health, nourishment, lusture, oja, teja (energy) and prana (life
energy).[1]
The audaryagni present inside the abdomen of animals is known by various names
such as Vaiswanara, Audarya tejas, Kayagni, Jatharagni, Kosthagni, and Pachakagni.
This agni is not in the form of flame as the terrestrial fire but is in the form of liquid which is
called as „Pitta‟ in Ayurveda. „There is no agni apart from pitta and pitta itself is agni‟ asserts
Charaka.[2]
The term „Pitta‟ is used to designate its physical or material form and the term
“Agni” to designate its functions. Sometimes these are used interchanging also. Further, Agni
is subdivided into thirteen kind‟s viz., one- Kosthangni, five-Bhutagnis and seven-
Dhatwagnis.
Kosthagni is the chief of all the other kinds. It is present inside the amasaya (stomach and
small intestines) and pakwasaya (large intestine), it attends to the function of digestion of
food and contributes modifies of itself to the other agnis also, thereby providing them with
strength. It is also known as Pachaka pitta. Though composed of all the panchamahabhutas it
is predominantly tejas (agneya), though it is liquid in form it is devoid of the qualities of
liquid viz. sita (cold), snigdha and is called Anala (fire) due to its predominant functions of
paka (cooking, digestion).[3]
Literary review
The study of Agni can be summarized according to the following points
1. General description of Agni in various Ayurvedic texts.
2. Normal physiological function of different types of Agni.
3. Significance of Agni
In Brahmasutra, Agni has been meant to be a sign of life in the body. Great value of Agni has
been shown by classical literature. Acharya Yasaka has given the etymology of the term
“Agni,” which is as follows: Agni = A + G + Ni. The word “A” denotes root “I,” meaning “to
go”; “G” denotes the root “Anja,” meaning “to glitter” or root “daha,” meaning “to burn” and
“Ni” means “to carry.” The etymology given by Yasaka, Shankaracharya
(vedantasutra shabda kalpa druma) illustrates that Agni carries everything in it.[4]
It moves
everywhere and metamorphoses substances, burns, assimilates, glitters and grows. Agni is a
pivot around which the remaining factors responsible for the maintenance of health and
causation of disease as well as decay revolve (Shabdakalpadrum).[5]
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In shabdakalpa druma, 61 synonyms of Agni have been compiled. These synonyms help in
explaining the nature and functions of the Agni, e.g., Vaishvanara, Sarva Paka, Tanoonpata,
Amivachatana, Damunasa, Shuchi, Vishwambhar, Rudra etc. (Shabdakalpadrum).[6]
Agni as pitta
The origin of Pitta is from “Tapa,” which means: (1) combustion/digestion – to give
nourishment to the body by digestion of ingested food, (2) to maintain heat – by means of
heat, it maintains the color, lusture, etc. of the body (Su.Su-21/5).[7]
Now, there is a question as to whether Pitta and Agni are both the same or are different? Does
any area exist of Agni without Pitta, or is it that Pitta is Agni? This should be clearly
understood. Different views have been suggested regarding Pitta and Agni by different
Acharyas. Some Acharyas consider Pitta to be Agni while others speak differently.
According to Acharya Sushruta, there is no existence of any other Agni in the body
without Pitta, because when there is increased digestion and combustion in the body due
to Ushna guna of Pitta, the treatment is like Agni (Su. Su. 21/09)[8]
Acharya Marichi has also
emphasized that the Agni present in the Pitta gives good or bad results when it is normal or
vitiated (Cha. Su. 12/11)[9]
Chakrapani has commented on “Pittantargatta,” that the function of Pitta inside the body is
not combustion but its work is to provide heat of Agni. Besides this, Acharya Shusrut has
described five types of Agnis as the variety of Pitta. Acharya Bhoj also
considered Pitta as Agni, digestive fire is included within Agni, which is specially meant for
different enzymatic activities of the body, i.e. pachana, deepan, bhedana, etc. (Chakrapani
Tika on Cha.Su-12/11).[10]
According to Hemadri, Pitta is of five divisions, which are located in the interior of
the pakvashaya and amashaya, although it is composed of panchabhutas. Because of an
increase of (predominance qualities of) tejas bhuta, it is devoid of liquidity (although it is a
liquid). Also, because it does not possess snigdha (viscidity), sita and such other properties of
apa bhuta, it is called by the term “Anal” because of its function of paka. It cooks the food,
dividing it into essence and waste separately. Being localized there, it bestows grace (help) to
the other Pitta present there and also the other dhatvagni present in the dhatus by giving them
strength (power of functioning), which is known as “Pachaka Pitta” (As.Hr.Su.12/10-12).[11]
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Different examples are available in our classics to indicate that Pitta is the same as Agni. But,
some doubts arise behind the concept of whether Pitta is Agni, e.g.
Why indulgence of aggravating factors like katu, vidahi, etc. reduces the strength
of Agni instead of enhancing it.
Appropriate example to highlight the above concept that ghee alleviates Pitta but
enhances Agni.
The quotation of Acharya Sushruta, Samadoshah samagnishcha (Su. Sha. 15/48)[12] has
clearly indicated that Pitta and Agni are not the same.
Pitta is originated by two words in Ayurveda is metabolism and maintain the haemostasis
(maintained heat in the body). By metabolism it will provide energy to the body by
metabolizing the food and by maintain the heat of the body it will provide shine and
enthusiasm to the body.[11]
It is explained by some Ayurvedic texts that there is no
existence of separate Agni in the body. The basic Agni that provides heat and has
metabolic functions in the body is Pitta in the body. This Pitta has many Gunas but its
main Guna that is Ushana Guna represents Agni and its function in the body.[12]
As the
Pitta situation in the body is formed of Panchmahabutas. So the Agni and Pitta has the
same composition. But there are many examples which are given in Samhitas that Grit is
Pitashamaka but it aggravates Agni. Even in Sushrut it is maintained that Samdhoshas
Samagni Samdhatu Mala Kriya indicates that Agni and Pitta are different.[13]
Types of agnis
Enumeration of the number of Agnis varies in various classical Ayurvedic texts, as shown
below
Charaka has mentioned about 13 Agnis. Jatharagni – 1, Bhutagni – 5, Dhatvagni – 7
(Ch.Chi.15/38).[13]
According to Acharya Sushruta, five types of Agnis are illustrated, viz. Pachakagni,
Ranjakagni, Alochakagni, Sadhakagni and Bhrajakagni. However, there is an indirect
reference of five Bhutagnis underlying in the brief description made to the transformation
of food stuff. (Sh.Su.21/10.).[14]
Vagbhata has described different types Agni, viz. – Bhutagnis – 5–Dhatvagnis – 7, –
Dhoshagni – 3 and– Malagni – 3.
Sharangadhara has recognized five pittas only (Pachak, Bhrajak, Ranjak,
Alochaka and Sadhak) (Sha.Sa.PU.K-5/32).[15]
Bhavamishra has followed Acharya Charaka and Vagbhata (Bh.Pu .Kh.-3/169,180).[16]
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Agni has been divided into 13 types according to the function and site of action. These are:
1. Jatharagni – one Agni present in the stomach and duodenum.
2. Bhutagni – five Agni from five basic elements.
3. Dhatwagni – seven Agni present, one in each of the seven dhatus.
Accordingly, they are classified into three groups, namely Jatharagni, Bhutagni and
Dhatvagni.
Jatharagni
Jatharagni is the Agni or bioenergy present in the Jathara (stomach and duodenum).
According to Ashtanga Hridaya, Jatharagni, the seat is grahani (duodenum), so called
because it withholds the food for a certain time inside the Amasaya (stomach) to facilitate
digestion. In the opinion of Dhanvantari, it is the Kala known as “Pittadhara,” situated at the
entrance of the Pakvashaya (intestine) and acting as a bolt to the door of the pathway/channel
of food. It is responsible for the duration of life, health, valour, ojas (essence of the dhatus),
strength of all the bhutagni and dhatvagni. The strength of the grahani is from Agni itself,
and the strength of Agni is from grahani. When the Agni undergoes vitiation, grahani also
gets vitiated and produces diseases (As.Hr.Sha.3/50-54).[17]
1 Jatharagni is considered to be the most important because each and every nutrient that one
ingests first comes to the Jathara and is subjected to the action of Jatharagni. Jatharagni
digests the food materials that consist of the five basic elements and transforms it for
utilization by the respective Dhatus paramanus (tissues).
Jatharagni is also responsible for separation of the food material into the essence portion
(Prasad) and the waste products (kitta) in our body (As.H Su-12/8).[18]
Jatharagni is directly related to Dhatvagni or bioenergy in the cells and their metabolic
processes, with ultimate tissue metabolism or Dhatu-Paka process. All the Dhatvagni depend
on the normal, healthy state of Jatharagni. If the Jatharagni is hyperactive (Tikshna) or
hypoactive (Manda), it will cause an excessive or retarded action of the Dhatvagni. This
disturbed action ultimately leads to various disorders. Jatharagni is the main
important Agni that controls the function of all other 12 Agnis. All the Agnis are totally
dependent on the status of Jatharagni (Cha. Chi. 15/39-40).[19]
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1. Jatharagni is also classified into four categories according to its performance of digestion
in the human being (Cha. Chi. 15/51),[20]
namely Vishamagni, Tikshanagni,
Mandagni and According to Hareet Samhita, Samagni depends on whether
the Doshas (Vata, Pitta, Kapha) are in normal stage. When the Pitta is higher than
normal, the condition is known as Tikshnagni. When Vata and Kapha are higher than
normal, the condition is known as Mandgni.
a. Samagni: The Samagni digests and assimilates food properly at the proper time. This thus
increases the quality of the Dhatus (supportive tissues of the body). Persons
having Samagni are always hale and healthy
b. Vishamagni: This type of Agni changes between digesting food quickly and slowly.When
this Agni is affected by the Vata Dosha, it creates different types of udargata roga.
c. Tikshnagni: Tikshnagni means very quick/very sharp/very fast. Tikshnagni is a state of
very quick digestion of food, regardless of the type of food. Acharya Shushrut states that
when the power of digestion is increased from normal to above normal, food digests very
quickly and produces hunger or the desire for food. When food is digested, the throat, the
mouth cavity and the lips become dry with a burning sensation. This condition is known
as “Bhasmak Roga” according to Ayurveda.
d. Mandagni: “Mand” means slow. The meaning of the Mandagni is slow digestive power
or digestive capacity. Those who are having Mandagni eat very little and are unable to
digest the smallest amount of food. Dhanvantri says that Agni digests the least amount of
food in the greatest amount of time.
2. Bhutagni. Bhutagnis are five in number, and present in the kosthagni or pachaka pitta
itself. These are known as parthivagni, apyagni, taijasagni, vayavyagni and nabhasagni.
They help the kosthagni in the digestion of food, especially to digest those kinds of foods
which are of identical nature4 Parthivagni specially helps in the digestion of parthiva kind
of food, apyagni the apya kinds of foods and so on. These bhutagnis derive their strength
(functional capacity) from the kosthagni itself.
Each and every cell in our body is composed of the five mahabhutas or five basic elements.
Naturally, each cell (dhatu paramanu) consists of these five Bhutagni also. All the nutrients
in this world that we eat also consist of the same five basic elements with their
respective Agni or bioenergies. Thus, they are completely similar with respect to the five
basic elements with their Bhutagni in our body cells as well in all the outside nutrient, that we
ingest for the nutrition of our body. Acharya Charak has mentioned that the
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five Bhutagni digest their own part of the element present in the food materials. After the
digestion of food by the Bhutagni, digested materials containing the elements and qualities
similar to each bhutas nourish their own specific bhautika elements of the body (Cha. Chi.
15/13, 14).[21]
These Bhutagnis act after the Jatharagni present in the stomach and
duodenum, acting on the food and causing their disintegration. In the modern physiological
perspective, the action of Jatharagni can be equated with the digestion in the stomach and
duodenum, and the action of the Bhutagni can be equated with the conversion of digested
materials in the liver.
3. Dhatvagni
All the seven Dhatus (seven element tissues of the body) contain their own Agni to
metabolize the nutrient materials supplied to them through their own Srotas.
1. Rasagni present in the Rasa Dhatu.
2. Raktagni present in the Rakta Dhatu.
3. Mamsagni present in the Mamsa Dhatu.
4. Medagni present in the Meda Dhatu.
5. Asthyagni present in the Asthi Dhatu.
6. Majjagni present in the Majja Dhatu.
7. Shukragni present in the Shukra Dhatu.
Each Dhatvagni or the bioenergy present in each Dhatu synthesizes and transforms the
essential Rasa Dhatu required for that particular Dhatu or cell from the basic nutrients
present in the AnnaRasa or essence of the diet that we consume. Each Dhatvagni has got a
speciality to synthesize and transform the constituents suitable to its particular Dhatu. This
action is a sort of selective action. Acharya Charaka has mentioned the fact that that the
seven dhatus that are a support of the body contain their own Agni, and by their
own Agni they digest and transform the materials supplied to them to make the substances
alike to them for assimilation and nourishment (Cha. Su. 28/15).[22]
Clinical significance of agni
Majority of the diseases are outcome of malfunctioning of the Agni which rightly has been
called as central root to health.Agni not only plays vital role in absorption of macro as well as
micronutrients, but is destructive to pathogens also. The food that in not properly digested is
referred as "Ama" in Ayurveda and it is nothing but a toxin or pathogen responsible for
diseases. Proper functioning of digestive fire is evident from normal tone of the digestive-
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system, circulatory-system, strong immunity or resistance against diseases, proper tissue
growth and body complexion. It is also the source of intelligence, nutrition and awareness in
the body. It coordinates many physiological processes of the body from the digestion,
reabsorption, sensations and formation of energy. This affects both body and mind of the
human being.
Ama can be explained in Ayurveda that it is the unhealthy, indigested food. It is the dry form
of the food which is considered to be waste product for the body. This Ama is formed by
Mandhagni which form Rasaja and food indigestion which act on sub cellular level and form
disease. Due to Mandhagni these undigested food particles start get accumulated in the body
and form Aama Dhosha. It is again explained as the undigested formed which is formed due
to the weakness of Jhatharagni and Dhatvagni is called as Ama. These are divided into three
Pakaavastha as-
In first Avastha due to weakness of Jhatharagni Ama get accumulated in Amashya (stomach).
In second Avastha due to weakness of Dhatvagni the Dhatus didn‟t get digested and form
Ama which is known as Ama visha.
In third Avastha the mostly undigested food gets accumulated and forms Ama.
This Ama food, Ama rasa, Ama Dhatus all are known as Ama. This Ama gets accumulated
and stay in body as an auto antigen which cause many autoimmune disorders which causes
allergies in the body. Due to these reactions many antibodies will be formed in the body
which ultimately causes many diseases and one of them is Amavata. Acharya Charak also
explained the undigested food as Amavisha[23]
There are many causative factors for Amavisha
which are divided into Aaharaja and Viharaja causes. Overeating, less eating, improper
eating, Guru, Sheet, Atirukhsha Aahar, preventing natural urges, day sleeping, lethargy. And
these all are the same reasons for the weakness of Agni in the body that is Mandagni, which
is the main reason for the formation of Ama. This Amavisha will form the symptoms in the
body which are stiffness, stasis of faecal matter, fatigue, headache, fainting, vertigo,
backache, yawning, malaise, vertigo, fever, thirst, anorexia, tenesmus, indigestion and these
symptoms will also be seen in improper functioning of the Agni.[24]
In modern the main
contents of food that is carbohydrates, proteins and fats are digested by Jhataragni,
Dhatvagni, Bhutagni and form a end product. Protein is converted into amino acids in the
presence of Jhataragni and in the presence of Dhatvagni it is converted into urea.
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Carbohydrates and fat end product is carbon dioxide and energy. If the Agni is in a condition
of Madhagni then there will be no formation of end product and intermediate product will be
formed which are lactic acids, uric acids and ketone bodies and they are a form of Ama. Due
to increased formation of these products they cause many diseases like Urusthamba,
Vatarakta (gout) and diabetes. This Ama can be correlated with many forms as the undigested
Ras Dhatu is form ofAma, accumulation of waste product is Ama, Dhosha Dhusti is also
Ama.
Ama related diseases which are caused due to Jhataragni are Alasaka, Visuchika, Atisara,
Vilambika, Pravahika, Amalpitta, Basamak Roga, IBS.
Ama related diseases which are caused due to Dhatvagni are Raspradhoshaj vikara, Rakhta-
pradhoshaja vikara, Masa pradhoshaj vikara, Medha pradhoshaja vikara etc. Madhumeha
(diabetes), Aamavata (rheumatoid arthritis), fever, Shawas (COPD), Sthaulya (obesity),
inflammation.
Ama related diseases which are caused due to Bhutagni are liver disorders, metabolic
disorders.
These all diseases are caused due to the formation of Ama which is formed by the imbalance
of the Agni in the body
DISCUSSION[25]
If digestive fire is not functioning properly, one has poor digestion, improper blood-
circulation, poor complexion, low energy levels, flatulence and poor immunity against
diseases. Thus promoting proper functioning of the digestive fire is treating the root cause of
the diseases, according to Ayurvedic principles. Thus a vicious cycle of impaired Agni and
the production of Ama is established. Understanding basic relationship between Ama and
Agni is of prime importance in treating the diseases. Maintaining good appetite, use of
digestive stimulants and ensuring regular bowel movements are of prime importance in
enkindling the digestive fire and preventing the production of root cause of all diseases, Ama.
This shows Agni has the most important role in Dosha Dhatu balance in the body and it will
produce diseases as it get imbalance in the body. In Ayurveda it has been said that with
decrease in functions of these thirteen types of Agni there will be production of disease.
CONCLUSION
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In this article after a brief discussion on Agni, Pitta and there correlations it shows that Agni
is important for digestion and metabolism on cellular level, it also signify the importance of
Agni on physiological levels. Agni is of 13 types which maintain the balance of metabolism in
the body, Agni which is Samagni (normal) maintains the health of a human being. Agni is
having many digestive enzymes which help to maintain the digestive and metabolic functions
of the body. By the indigestion due to imbalance of Agni they produce Ama, which produce
diseases. This Ama can be formed at any level of Pakavastha of the food. So the management
of Agni Dhusti can lead to a healthy life. In this article this is concluded that if there is
imbalance in Agni there will be production of diseases. So according to Ayurveda Agni is
important for human body and its proper functioning. In Ayurveda, the theory of Agni or
biological fire is of prime importance. Agni is among the critical factors in determining
optimal health and internal homeostasis. On the contrary, Ama is a toxin or pathogen,
responsible for aetiology of all diseases.
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