Healthy Ageing through Technoculture
Transcript of Healthy Ageing through Technoculture
Healthy Ageing through Technoculture
Marios KyriazisELPIs Foundation for Indefinite Lifespans
www.elpisfil.org
How to conquer ageing
•Biotechnology?•Drugs and supplements?
•Nanotechnology?•Stem cells?
•Artificial Intelligence?
The fallacy of the longevity elixirPROBLEMS:
•Stem cells: harvesting, delivery, compatibility, bone marrow transplants
•Tissue engineering: harvesting, surgical transplants
•Genetic therapies: technical issues, delivery, integration in the body
•Nano-medicine: unknown results, side effects•Pharmacological therapies: compliance, interactions, polypharmacy
ELIMINATION OF AGEING
BIOLOGY
EPIGENETICS
LIFESTYLE
REPAIR
BIOMEDICINEREPRODUCTIO
N
GENDER
EVOLUTION
CULTURE ETHIC
S
CONFLICT RESOLUTIO
N
RISKS
TECHNOLOGY
HYPER CONNECTIO
N
GLOBAL BRAIN
COMPLEXITY SCIENCE
CYBERNETICS
SOCIETY
ENVIRONMENT
SMART CITIE
SPOLITI
CS
Both concepts are based on INFORMATION
A meaningful set of data or patterns which influence the formation or transformation of other data or patterns, in order to reduce
uncertainty and help achieve a goal
How to increase information content
1. Enriched environment, hormetic challenges
2. Social hyper-connectivity (real and virtual/online)
3. Behavioural models: goal-seeking behavior, search for excellence, a bias for action
4. The pursuit of innovation, diversification, creativity, novelty, and the avoidance of routine.
HormesisAn adaptive response of cells and organisms to a moderate, intermittent, challenge.Hormesis describes phenomena where there is low dose stimulation, high dose inhibition.Nutritional, physical, mental and chemical challenges may result in mild damage which upregulates repair mechanisms. In an attempt to repair this damage, age-related damage is also repaired.
Environmental Enrichment
Experimental animals are exposed to an enriched environment- a habitat augmentation. This has several positive effects on health, specifically on brain and immune function.
ChallengeHere, a challenge is defined as a situation that
potentially carries biological value for an organism, so that the organism is inclined to act. A challenge provokes
action because it represents a situation in which not acting will lead to an overall lower fitness than acting.
The balance between age-related degeneration and health depends on: A. How well our repair processes are maintained through artificial (item-
based) pharmacological, genetic, cellular, biotechnological and other physical interventions.
B. Through utilising challenging exposure to information with consequent improvement of function.
An Irregular, Useful Guest
Second, usefulness•Humanity is not going to improve if its members don't make an effort to achieve something higher.
Third, quest
•Always seek novelty, never be satisfied, never sit quiet and 'relax' for long periods. Be inquisitive, always ask 'why' and don't take anything at face value.• Try to get to the top but don't stop there. There is always something higher. •Come up with new ideas, and then try to achieve them.
First, irregularity
We thrive on change, challenges and unexpected events. A ‘power-law’ lifestyle: frequent low level activities, some medium level ones, and rare intense activities.Ever-changing, imaginative and unpredictable activities improve immunity, reduce inflammation, improve nerve-growth factors, and many others.
The end?
ELPIs Foundation for Indefinite [email protected]
Meeting to discuss these concepts: 3rd Symposium ‘Pathways to Indefinite Lifespans’0n Saturday 23 May 2015, In Larnaca, Cyprus