Gut Editorial Committee

J J MISIEWICZ(Editor)

D 1, WIN(GATE(Book Review Editor)

A ALLENS R BLOOMR M CASE

R COCKEI,I) COLIN-JONESJ H CUMMIN(SA CUSCHIERIS J W EVANSJ F FIELDINGA GARNERR C HEADIN(GR V HEATLEY

M R B KEIU'HLEYW R LEESA S McNEISHP J MILLAT J PETERSA B PRICEN W READI TAYLORD TRIG(ER

G T WILLIAMSROGER WILLIAMSR C N WILLIAMSON

EDITORBritish MedicalJournal

SHIRLEY Mc(GEALEY(Technical Editor)

Gui publishes original papers and reviews concerned withpractice and reseairch in gastroenterology. The field is thatof basic science and physiology pertaining to the alimentarytract, the liver and pancreas and that of alimentary, hepatic,biliary or paincreiatic disease. Papers may deal with medical,surgical, or epidemiological aspects or with imaging. A cascreport will be accepted only if it dealls with a clinical problemwhich has been studied in detail and the resulting dataprovide material for further research. Letters dealing withmatters arising from articles published in Gut, or with topicsof general professional interest are encouraged, but thecorrespondence column should not be used for publicationof original data.

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ISSN ()(17-5749

1556 Rees

17 Wallace JL, Whittle BJR. Role of mucus in the repair of gastric epithelial damage in the rat.Inhibition of epithelial recovery by mucolytic agents. Gastroenterology 1986; 91: 603-11.

18 Hills BA, Butler BD, Lichtenberger LM. Gastric mucosal barrier: hydrophobic lining to thelumen of the stomach. Am J Physiol 1983; 244: G561-8.

19 Younan F, Pearson J, Allen A, Venables C. Changes in the structure of the mucus gel on themucosal surface of the stomach in association with peptic ulcer disease. Gastroenterology1982; 82: 827-31.

20 Isenberg JI, Selling JA, Hogan DL, Thomas FJ, Koss MA. Duodenal ulcer patients haveimpaired proximal duodenal mucosal bicarbonate secretion. Gastroenterology 1986, 90:1472.

The Editor and Technical Editor wish all readers of Gut a Happy Christmasand Prosperous New Year.

Forthcoming Scientific Meetings ofthe British Society of Gastroenterology

SPRING 1988 23-25 MarchUniversity of Leicester

AUTUMN 1988 13-16 SeptemberUniversity of Sheffield

For details of registration please contact:

The Administrative Secretary,BSG, 3 St Andrew's Place,

Regent's Park,London NW1 4LB.

Tel: 01-387 3534 (International 44-1-387 3534)

Forthcoming Scientific Meetings ofthe British Society of Gastroenterology

SPRING 1988 23-25 MarchUniversity of Leicester

AUTUMN 1988 13-16 SeptemberUniversity of Sheffield

For details of registration please contact:

The Administrative Secretary,BSG, 3 St Andrew's Place,

Regent's Park,London NW1 4LB.

Tel: 01-387 3534 (International 44-1-387 3534)

Volume 28 General Index

Abdominal. See lntraabdominalABOU7EKRY, L. See BANNIS'I'ER, J J, ABOU/EKRY, L, et al.

Abscesses of liver, listerial, multiple (Case report), 1661Aehalasia, 24 hour ocsophagecal acidity beforc and after pneumatic

dilatation in, 883Achalasia-like disorder of ocsophagus in von Recklinghausen's

neurofibromatosis (Case report), 1522Achlorhydria and hypergastrinaemia as causal sequence for gastric

carcinoid tumours, reasscssmcnt of (Progress report), 488;(Letters), 1189, 1191, 1319

ACTH-stimulatcd and basal steroidogenesis, dose related in vitroeffects of cimetidine and ranitidine (Letters), 1688, 1690

Adenocarcinoma of small bowel and neurofibromatosis, associationbetween (Case report), 1173

Adenoma, hepatoecllular, primary, rupture of, in adult man,spontaneous haemoperitoneum from (Case report), 1170

Adenoma-careinoma sequence and plasminogen activators inexperimental colorectal neoplasia, 816

Adenomatous polyposis, familial, biliary tract pathology in, assess-ment of (Letters), 1320

- ,-, gastric and duodenal polyps in, nature and preval-ence, 306

Adenovirus, intestinal, human, role in pathogenesis of coeliacdisease, evidence for, 995

ADI ERCREUTZ, H. See HAMALAINEN, E, KORI'ELA, J '1, et al.ADNANI, M S. See KHUFFASH, F A, BARAKAI, M H, et al.

Adrenal endocrine tumour, mixed, causing steatorrhoea (Casereport), 1298

ADRIAN, I E. See GO(DLAD, R A, ENTON, w, et al.See SAVAGE, A P, ADRIAN, I E, et al.

AFDHAL, N H, LONG, A, 'rOBBIA, 1, CULLEN A, and O DONOGHUE, D P:

Immunohistochemical Cal9-9 in primary colonic polyps andpolyps synchronous with colorectal cancer, 594; (Reprintted), 1049

Aging, effect on anorectal function, 353AHNFELI-R0NNE, t. See NIELSEN, H, AHNFELT-RONNE, I, et al.AIDS, cholangitis in (Case reports anid review), 1653

c, ytomegalovirus colitis and oesophageal ulceration in, clinicalmanifestations and treatment with Foscarnet (Case report), 482

AIDS-related Kaposi's sarcoma presenting as ulcerative colitis andcomplicated by toxic megacolon (Case report), 1302

AINLEY, C C. See MAXTON, D G, AINLEY, C C, et al.AITKEN, R J: Assessment of biliary tract pathology in familialadenomatous coli (Letter), 1320

AKAGI, M. See SAKAMOTO, K, HAGA, Y, et al.AKESSON, B. See THESLSEFF, P, BENONI, C, et al.Albendazole sulphoxide, penetration into hydatid cysts, 75Alcohol, absolute, endoscopic sclerotherapy using (Letter), 777Alcoholic cirrhosis, hepatic intestinal uptake and release ofcatecholamines in, evidence of enhanced hepatic intestinalsympathetic nervous activity in, 1637

-hepatitis, acute, cellular injury in, free radical generation byneutrophils as potential mechanism of, 1157

ALDERSLEY, M A. See ROBER'I'SON, D A F, ALDERSLEY, M A, et al.ALEXANDER, G. See ANDERSON, M G, HARRISON, r J, et al.Alkaline secretion, gastric and duodenal, stimulated by De-Nol

through prostaglandin dependent mechanism, 1557in normal subjects and in duodenal ulcer, vagal

cholinergic control of, 739; (Letters), 1687At LAM, B F, TILLMAN, J E, THOMSON, I J, CROSSLING, F T, and GILBERtl',

L M: Effective intravenous cyclosporin therapy in a patient withsevere Crohn's disease on parenteral nutrition (Case report), 1166

ALLAN, R N. See ANDREWS, H, BARCZAK, P, et al.ALLEN, A. See SELLERS, L A, ALLIEN, A, et al.ALLEN-MERSH, T G, KEMENY, N, NIEDZWIECKI D, SHURGO'I', B, and DAt.Y,

i M: Significance of a fall in serum CEA concentration in patients

treated with cytotoxic chemotherapy for disseminated colorectalcancer, 1625

ALLISON D J. See 'I'HOMPSON, J N, SALEM, R R. et al.Al MARDINI, H, I INDSAY, D C, DEIGHTON, C M, and RECORD, C (: Effect

of polymer coating on faccal recovery of ingested 5-amino salicylicacid in patients with ulcerative colitis, 1084

Alpha-I and alpha-2 adrenoceptors, involvement in postlaparotomyintestinal motor disturbances in rat, 955

ALTMAN, D G. See HILL, I D, and AL'I'MAN, D G

p-Aminobenzoic acid. See PABA5-Aminosalicylic acid given intravcnously or released at different

sites in gastrointestinal tract. metabolism and urinary excretion inhealthy volunteers, 196

ingested, faccal recovery in ulcerative colitis, effect ofpolymcr coating, 1084

p-Aminosalicylic acid, PABA test with, improved specificity of, 468AMMON, H V, FOWLE, S A, CUNNINGHAM, J A, KOMOROWSKI, R A, and

l OEFFLER, R F: Effccts of auranofin and myochrysine on intestinaltransport and morphology in the rat, 829

See also KARAUS, M, SARNA, S K, et al.Amoebic infection in guinea pigs, alterations of humoral, cell

mediated and antibody dependent cell mediated cytotoxicresponses during, 1251

Ampulla of Vater, carcinoid tumour of, presenting as acutc pancre-atitis (Case report), 1296

Amyloidosis, lambda-AL, cholestasis and liver failure with (Casereport), 903

Anal canal pressure profile, rcappraisal as determined by rapidpullthrough technique, 1234

ANAND, B S. See KUMAR, A, KUMAR, N, et al.See SARIN, S K, NANDA, R, et al.

- See SARIN, S K, SACHDEV, G K, et al.Anastomoses, colonic, proliferative instability and experimental

carcinogenesis at, 808Anastomotic recurrence of colorectal cancer, biological phenome-non or avoidable calamity'? (Leading article), 786; (Letter), 1691

ANDERSEN, J R. See MANNICHE, C, MALCHOW-M0LLER, A, et al.ANDERSON, M (G, HARRISON, T J, ALEXANDER, G, 7UCKERMAN, A J, andMURRAY-LYON, I M: Randomised controlled trial of lymphoblastoidinterferon for chronic active hepatitis B (Clinical trial), 619

ANDREWS, H, BARCZAK, P, and ALLAN, R N: Psychiatric illness inpatients with inflammatory bowel disease, 1600

ANGELIN, B. See EINARSSON, K, ANGELIN, B, etal.Anorectal function, effect of aging, 353AN'TELL, L A. See KARLSTAD'I', R G, FRANK, w O, et al.Antibodies, complement fixing, against lipopolysaceharides from E

coli, absence in subgroup of patients with Crohn's disease, 1460Antibody dependent cell mediated, cell mediated and humoral

cytotoxic responses, alterations during amoebic infection inguinea pigs, 1251

Antigen, carcinoembryonic. See Carcinoembryonic antigenAntigens, dietary, passagc into blood of coeliac children, and

quantification and sizc distribution of antigens, 1062Anti-inflammatory drugs, non-steroidal, adverse cffects, incidenceand avoidance (Leading article), 515

and life threatening complications of peptic ulcera-tion, 527

and peptic ulcer (Letters), 111and prostaglandins, effect on permeability of

human small intestine, statistical assessment (Letters), 777,- ,influence on treatment of peptic ulcer in patients

with rheumatic disease (Clinical trial), 226Anti-muscarinic and H2 reccptor blockade, combined, in healing of

refractory duodenal ulcer, 1505Antisecrctory drugs for acid suppression in duodenal ulcer, optimal

dosing defined by meta-analysis, 1120c1-Antitrypsin and ".'In-labelled granulocytes, faceal excretion of, inassessment of disease activity in chronic inflammatory boweldiseases, 386

ANION, P. See BUl'LER, T, DAHMS, B, et al.

1693

1694

ANIONIN, K H, and BIECK, P R: Transdermal scopolamine and gastricacid secretion (Letter), 1686

Antroduodenal motility and transpyloric fluid movement in patientswith gastro-oesophageal reflux, 545

Arachidonate and metabolites extracted from human normal andmalignant gastrointestinal tissues, measurement of, 315

Arachidonic acid composition of phospholipids, increase in colonicmucosa in active ulcerative colitis, 1002-metabolism, abnormal, in chronic inflammatory bowel

disease with enhanced release of Ieucotriene B4 from activatedneutrophils, 181

ARATO, A, SAVILAHTI, E, J'AINIO, V-M, VERKASALO, M, and KLEMOLA, T:HLA-DR expression, natural killer cells and IgE containing cellsin the jejunal mucosa of coeliac children, 988

ARCHIMANDRI'I'IS, A, IZIVRAS, M, DELLADEIlSIMA, A, andTiRYPiHONOS, M:

Collagenous colitis in Greee (Letter), 230ARM, J P. See BLOODWORTH, L. L, S'i'EVENS, P E, et al.ARMS'I'RONG, C P, and BLOWER, A L: Non-steroidal anti-inflammatory

drugs and life threatening complications of peptic ulceration, 527Arthritis, reactive, intestinal inflammation related to, histo-pathology of, 394

ASALA, S A, BOWER, A J, and l.AWES, I N C: Effccts of partial truncalvagotomy on intragastric pressure responses to vagal stimulationand gastric distension in ferrets, 1569

Aspiration cytology, needle, endoscopic, in diagnosis of uppergastrointestinal cancer, 1142

Aspirin, chronic gastric ulccration in rat induced by, degree of,molecular weight of gastric mucus glycoprotein as predeterminantof, 287

ATKINSON, M: Monitoring oesophageal p I (Leading article), 509See also FOSTER, P N, STEWART, M, et al.See also SMART, H L, FOSIER, P N, et al.

Auranofin and myochrysine, effects on intestinal transport andmorphology in rat, 829

AUSTIN, R K. See KAGNOFF, M F, PArFERSON, Y J, et al.Autonomic stimulation, centrally mediated, action on upper gastro-

intestinal transit, comparative study of 2 stimuli, 960AXELSSON, C K. See SzECSI, P B, HALGREEN, H, et al.AXON, A I R, BO'I'I'RILL, P M, and CAMPBELL, D (for BSG Working Party

on the Staffing of Endoscopy Units): Results of a questionnaireconcerning the staffing and administration of endoscopy inEngland and Wales, 1527

See also MANNING, A P, BULGIM, 0 R, et al.AZAD, M A K. See BUTLER, 1, DAHMS, B, et al.

BACA, M E, MOWAI, A MCI, MACKENZIE, S, and PARRoIl, D M V:Functional characteristics of intraepithelial lymphocytes frommouse small intestine, III. Inability of intraepithelial lymphocytesto induce a systemic graft-versus-host reaction is because of failureto migrate in vivo, 1267

BACKON, J: Ginger and carbon dioxide as thromboxane synthetaseinhibitors: potential utility in treating peptic ulceration (Letter),1323

Bacterial infection problems in liver disease (Progress report), 623metabolism, colonic, effect of changing transit time, 601proteases, colonic, to IgA, and sIgA in ulcerative colitis, 186;

(Letter), 917BAGSHAW, P F, MUNSIER, D j, and WILSON, J G: Molecular weight of

gastric mucus glycoprotein is a determinant of the degree ofsubsequent aspirin induced chronic gastric ulceration in the rat,287

BAKLIEN, K. See VALNES, K, BRAND[FZAEG, P, et al.BANCEWICZ, J. See MUGHAL, M M, MARPLES, M, et al.BANNISTER, J J, ABOUZEKRY, L, and READ, N w: Effect of aging on

anorectal function, 353DAVISON P, 'I'IMMS, J M, (IBBONS, C, and READ, N w: Effect of

stool size and eonsistency on defecation, 1246GIBBONS, C, and READ, N W: Preservation of faecal continence

during rises in intra-abdominal pressure: is there a role for the flapvalve'?, 1242

General index

BARAKAI, M ti. See KHUFFASH F A, BARAKAI, M H, et al.BARBARA, L. See CORINALDESI, R, STANGHELLINI, v, eta l.BARBA'I'IS, C. See CUVELIER. (C, BARBAIIS, c, et al.BARC/AK P. See ANDREWS, H, BARC/AK, 1', et al.BARDHAN, K D, IHOMPSON, M, BOSE, K, HINCHLIFFE, R F C, CROWE, J,

WEIR, D CG, MCCAR'I'HY, C, WALIERS, J, IHOMSON, I J, IHOMPSON,M H, GAIT, J . KING, C, and PRUDHAM, D: Combined anti-muscarinicand H2 receptor blockade in the healing of refractory duodenalulcer: a doubie blind study (Clinical trial), 1505

BARR, G D, HUDSON, M J, PRIDDlE, J D, and JEWELL, D ': Colonicbacterial proteases to IgA, and sigA in patients with ulcerativecolitis, 186

BARR, 1i. See BOWN, S G, HAWES, R, et al.See KRASNER, N, BARR, H, et al.

BARRISON, i. See WEBER, J N, lHOM, S, et al.BARRY, R E. See WILLIAMS, A J K, and BARRY, R E

BARIER, S. See GUPI'A, S, BARTER, s, et al.BASSO'l-I'I, G. See NARDUCCI, F, BASSO'I-I'I, G, et al.BA'I-1, R M, HART, C A, MCLEAN, I., and SAUNDERS, J R: Organ culture of

rabbit ileum as a model for the investigation of the mechainism ofintestinal damage by cnteropathogenic Esclierichia coli, 1283

BA'I-I'AGLIA, 0, DI MARIO, F, PICCOII, A, VIANELIO, F, FARINAII, F, andNACCARATO, R: Clinical markers of slow healing and relapsinggastric ulcer, 210

BAUERFEIND, P, Cli LUFFO, I, FIMMEL, C J, EMDE, C, RIl'TER, C VON,KOHLER, W, GU(GiLER, R, GASSER, T, and BLUM, A 1: Does smokinginterfcrc with the effect of histaminc H2-receptor antagonists onintragastric acidity in man?, 549

BAVARIAN CONS'I'IPA'I'ION S'I'UDY (ROUP and MUILER-LISSNER, S A:

Treatment of chronic constipiation with cisapride and placcbo(Clintical trial), 1033

BAXIER, J N, GRIME, J S, CRITCHI EY, M, JENKINS, S A, and SHIELDS, R:

Rclationship between gastric emptying of a solid meal andemptying of the gall bladder before and after vagotomy, 855

See also MACKIE, C R, BAX'I'ER, J N, etal.See also PARR, N J, GRIME, J s, et al.

BECK, H. See JENSEN, S L, HOLS'I', i J, et al.BECKER, W. See FISCHBACH, W, BECKER, W, et al.BEEKEN, W, NORI'HWOOD, 1, BELIVEAU, c, and GUMP, D: Phagocytes in

ccll suspensions of human colon mucosa, 976BELAICHE, J, ZFI-l'OUN, J, MARQUEI, J, YVART, j, and CA'I'AN, D: Itn vitro

effect of duodcnal juice on R binders cobalamin complexes insubjects with pancreatic insufficiency: corrclation with cobalaminabsorption, 70

BELIVEAU, C. See BEEKEN, W, NORIHWOOD, I, et al.BENHAMOU, J-P. See ROULO'I', D, VALLA, D, et al.BENNE'Il-l, A, CIVIER, A, HENSBY, C N, MELHUISH, P B, and STAMFORD, F:Measurement of arachidonate and its mctabolites extracted fromhuman normal and malignant gastrointestinal tissues, 315

BENNETT, J R. See cox, J, and BENNE'I-I', J RBENNETTr, M K. See SELLERS, L A, ALLEN, A, et al.BENONI, C. See THESLEFF, P, BENONI, C, et al.BERGH, F AJ TM VAN DEN. See HOEK, F J, BERGH, F A J M VAN DEN, etal.BERRY, A R. See DIXON, J M, CHAPMAN, R w, etal.BERSIOCK, D A. See MCINERNEY, P D, VAN DESSEL, MG, et al.Beta-blockade, development of cirrhosis in response to, changes in

blood flow, portal pressure and shunting during, 663BHASIN, D K, KOCHHAR, R, and MEHIA, S K: Portal hypertensive gastricmucosa (Letter), 1324

BHASKAR, N K. See WALT, R P, KEMP, R ir, et al.BHAIIA, D. See CHAKRABORIY, -r K, BHAlIA, D, et al.BIANCHI PORRO, G, PARENTE, F, and LAZZARONI, M: Tripotassium

dicitrato bismuthate versus two different dosages of cimetidine inthe treatment of resistant duodenal ulcers (Cliniical trial), 907

,and PETRIL[.O, M: Disodium cromoglycate and prednisoloneenemas in the treatment of ulcerative colitis (Letter), 1323

BIANCONE, L. See PALLONE, F, FAIS, s, et al.Bicarbonate and prostaglandin E, output by normal humanstomach, effect of luminal pH, 1291

BIECK, P R. See AN-I'ONIN, K H, and BIECK, P R

General index

BIELAN~SKI, W. See KONTUREK, S J, POPIELA, T, et al.BIEMOND, 1, LANGE, G G DE, WETERMAN, I T, and PENA, A S:

Immunoglobulin allotypes in Crohn's disease in the Netherlands,610

BIGGS, B A, CROWE, S M, LUCAS, C R, RALSTON, M, THOMPSON, I L, andHARDY, K J: AIDS related Kaposi's sarcoma presenting as ulcera-tive colitis and complicated by toxic megacolon (Case report),1302

Bile acid concentrations, intragastric, unrelated to flatulent dyspep-sia in patients with and without gallbladder disease and post-cholecystectomy, 131

malabsorption in functional diarrhoea, detection of,75SeHCAT test results and correlation with small bowel transit,970

- secretion in cystic fibrosis (Letter), 506-acids, duodenal, relationship to colorectal neoplasia, 1454

, unconjugated, serum concentrations, increase in, intest-inal involvement in progressive systemic sclerosis detected by, 446

reflux equal in healthy controls and gastric ulcer patients, 1577salts, secondary, metabolism of, effect of long term lactulose

ingestion, and potential protective effect of lactulose in coloniccarcinogenesis, 675

Biliary disease, portal hypertension in, development of, role of liveratrophy, hepatic resection and hepatocyte hyperplasia in, 1022

-lipid metabolism in chronic pancreatitis, influence of steatorr-hoea, 1495

-tract pathology in familial adenomatous coli, assessment of(Letters), 1320

BILLY, H T. See DUBICK, M A, CONTEAS, C N, et al.BILSKI, J. See KONTUREK, S J, BILSKI, J, et al.BINDER, V. See S0RENSEN, V Z, OLSEN, B G, et al.Biopsy, fine needle, effect of needle size in (Letter), 912

for cytology, histology or both (Leading article),233

ultrasonically guided, in histologic differentialdiagnosis of focal liver lesions, 237

BIRNIE, G G, THOMPSON, G G, MURRAY, T, WATKINSON, G, and BRODIE,M J: Enhanced oral bioavailability of meptazinol in cirrhosis, 248

BISHOP, P E, MCMILLAN, A, and GILMOUR, H M: Immunological study ofthe rectal mucosa of men with and without human immuno-deficiency virus infection, 1619

Bismuth subcitrate, colloidal. See De-NolBJARNASON, I, and PETERS, T J: Helping the mucosa make sense ofmacromolecules (Leading article), 1057

, WILLIAMS, P, SMETHURST, P, PETERS, T J, and LEVI, J A: Intestinalpermeability and statistics (Letter), 777

BLACKWELL, J N. See DE CAESTECKER, J S, BLACKWELL, J N, et al.BLAND, J M. See CHAMBERS, J B, PRYCE, D, et al.Bleeding. See HaemorrhageBlood flow, mesenteric, effect of exercise, 583

-,portal pressure and shunting, changes during develop-ment of cirrhosis in response to beta-blockade, 663-stasis, temporary, with degradable starch microspheres

for liver metastases in rat model, 1201of coeliac children, passage of dietary antigens into, and

quantification and size distribution of antigens, 1062,peripheral, and intestinal lamina propria, lymphocyte activa-

tion in Crohn's disease defined by expression of early activationantigens in, 745

, portal, hepatic and venous, and large intestine, human, shortchain fatty acids in, 1221

BLOODWORTH, L L, STEVENS, P E, BURY, R F, ARM, J P, and RAINFORD, D J:Emphysematous gastritis after acute pancreatitis (Case report),900

BLOOM, S R. See GOODLAD, R A, LENTON, W, et al.See SAVAGE, A P, ADRIAN, T E, et al.See SAVAGE, A P, MAITHEWS, Ji, et al.See SPILLER, R C, LEE, Y c, et al.

BLOWER, A L. See ARMSTRONG, C P, and BLOWER, A LBLUM, A L. See BAUERFEIND, P, CILLUFFO, T, et al.

1695

See EMDE, C, GARNER, A, et al.BLUMGART, L H. See HADJIS, N S, and BLUMGART, L HBOESBY, S. See GUSTAFSEN J, BOESBY, s, et al.BOIRIVANT, M. See PALLONE, F, FAIS, S, et al.Book reviews:

BAYLESS, T M: Current therapy in gastroenterology and liver disease-2,1986,919

BRANSKI D, et al., eds: Paediatric gastroenterology: aspects ofimmunology and inJection, 1986, 1324

BROSTOFF, J, and CHALLACOMBE, s J, eds: Food allergy andintolerance, 1987, 1551

CLINCH, D, ed: Peptic ulcer and its drug causations: the role ofnon-steroidal anti-inflammatory drugs, 1986, 231

Clinical gastroenterology, Vol 1, No 1, Liver tumours, 1987, 1325Clinics in gastroenterology: Portal hypertension, 1985, 507

Symptoms in gastroenterology, 1985, 507Vol 15, No 1, Paediatric gastroenterology,

1986,507-, Vol 15, No 2, Endoscopy, 1986, 1549

Clinics in tropical medicine and communicable diseases, 2, Viralhepatitis, 1986, 1551

DAY, D w: Biopsy pathology of the oesophagus, stomach andduodenum, 1986, 1324

FIELDING, J W L, and PRIESTMAN, TJ, eds: Gastrointestinal oncology,1986, 920

FILIPE, M I, and JASS, J R, eds: Gastric carcinoma, 1986, 779Frontiers of gastrointestinal research, Vol 12, Cancer of the

exocrine pancreas, 1986, 230FRY, D E, ed: Reoperative surgery ofthe abdomen, 1986, 365FURNESS, J B, and COSTA, M: The enteric nervous system, 1987, 1550HEATLEY, R V, LOSOWSKY, M S, and KELLEHER, J, eds: Clinical

nutrition in gastroenterology, 1986, 920JOHNSON, A G, and TRIGER, D R: Liver disease and gallstones - the

facts, 1987, 1550MCCONNELL, R, et al., eds: The genetics and epidemiology of

inflammatory bowel disease, 1986, 1056MANUEL, P D, WALKER-SMITH, J A, and TOMKINS, A, eds: Infections of

the gastrointestinal tract, 1986, 112MAY, G, and GARDINER, R: Clinical imaging of the pancreas, 1987,

1552NI1-GIBOW, A J, and BALTHAZAR, E J, eds: Computed tomography of

the gastrointestinal tract, 1986, 919MEYERS, M A, ed: Computed tomography ofthegastrointestinal tract

including the peritoneal cavity and mesentery, 1986, 113MISIEWICZ, J J, POUNDER, R E, and VENABLES, C W, eds: Diseases of

the gut and pancreas, 1987,918, et al., eds: Atlas ofclinical gastroenterology, 1987, 1692

OSTROW, J D, ed: Bile pigments andjaundice: molecular, metabolic,and medical aspects, 1986, 365

Recent advances in gastroenterology, 1986, 1550Recent advances in hepatology, Vol 2, 1986, 364ROBINSON, PJ A, ed: Nuclear gastroenterology, 1986, 365ROZEN, P, and WINAWER, S J, eds: Secondary prevention of

colorectal cancer, 1986, 507Silvergirl's Surgery - biliary tract (ed J 0 Robinson), 1987, 1325SKOLNICK, M L, ed: Guide to the ultrasound examination of

the abdomen, 1986, 1056Topics in gastroenterology, 13, 1985, 644

,1986,779TRIGER, D R, ed: Clinical immunology of the liver and gastro-

intestinal tract, 1986, 508TYTGAT, G N J, and TIO, T L: Atlas oftransintestinal ultrasonography,

1986,779WANEBO, H J, ed: Hepatic and biliary cancer, 1987, 778WILLIAMS, R, ed: Liverfailure, 1986, 112

Books received, 113,232BOOTH, 1. See LASK, B, JENKINS, J, et al.BORCH, K, RENVALL, H, LUNDIN, c, and WAHREN, B: Evaluation of

gastric carcinoembryonic antigen analysis as an aid during screen-ing for gastric neoplasia in atrophic gastritis, 26

1696

BORDI, C, CREUTZFELDT, W, HAKANSON, R, SOLCIA, E, and SUNDLER, F:Achlorhydria: hypergastrinaemia: carcinoids - a flawed hypo-thesis (Letter), 1189

BORNMAN, P C. See KALVARIA, 1, BORNMAN, P C, et al.BOSE, K. See BARDHAN, K D, THOMPSON, M, etal.BOTTRILL, P M. See AXON, A T R, BOTTRILL, P M, et al.BOULOS, P B. See BOWN, S G, HAWES, R, et al.

See GELISTER, J S K, LEWIN, M R, etal.BOULTON, P. See SANDERSON, I R, BOULTON, P, et al.Bowel. See Intestine(s)BOWER, A J. See ASALA, S A, BOWER, A J, et al.BOWN, S G, HAWES, R, MATTHEWSON, K, SWAIN, C P, BARR, H, BOULOS,

P B, and CLARK, C G: Endoscopic laser palliation for advancedmalignant dysphagia, 799

BOYLE, P. See GALLOWAY, D J, JARRETT, F, et al.BOYLSTON, A. See WEBER, J N, THOM, S, et al.BRADSHAW, M J. See BROWN, A M, BRADSHAW, M J, et al.Bradykinin in carcinoid syndrome, 1417Bran efficacious in irritable bowel syndrome? (Clinical trial), 221BRANCH, W J. See CUMMINGS, J H, POMARE, E W, et al.BRANDTZAEG, P. See KETT, K, and BRANDTZAEG, P

See VALNES, K, BRANDTZAEG, P, et al.BRAYE, S. See MCLAREN, M, BRAYE, S, et al.Breath test, hydrogen, evaluation of, and definition and elimination

of early hydrogen peak, 721BREEN, E G, FARREN, C, CONNOLLY, C E, and MCCARTHY, C F:

Collagenous colitis and coeliac disease (Letter), 364BRENNAN, 1' G. See MONSON, J R T, RAMSDEN, C w, et al.BRITISH SOCIETY OF GASTROENTEROLOGY, Endoscopy Section Com-

mittee: Report - Future requirements for colonoscopy in Britain,772

Working Party on the Staffing of EndoscopyUnits: Report, 1682

Results of a questionnaire concerning the staffing and administra-tion of endoscopy in England and Wales, 1527

BRODIE, M j. See BIRNIE, G G, THOMPSON, G G, et al.BROOR, S L. See SARIN, S K, NANDA, R, et al.BROSTROM, O. See LOFBERG, R, TRIBUKAIT, B, etal.BROWN, A M, BRADSHAW, M J, RICHARDSON, R, WHEELER, J G, and

HARVEY, R F: Pathogenesis of the impaired gall bladder contractionof coeliac disease, 1426

BROWN, C. See EDWARDS, C A, HOLDEN, s, etal.BROWN, N J, RUMSEY, R D E, and READ, N w: Adaptation of hydrogen

analysis to measure stomach to caecum transit time in the rat, 849BRUN-VEZINET, F. See ROULOT, D, VALLA, D, et al.BRZOZOWSKI, T. See KONTUREK, S J, RADECKI, T, et al.BUCHANAN, K. See MCCOLL, K E L, BUCHANAN, N M M, et al.BUCHANAN, N M M. See MCCOLL, K E L, BUCHANAN, N M M, et al.Budd-Chiari syndrome, diagnosis of, comparison of ultrasono-

graphy, computed tomography and "mTc liver scan in, 242BUDILLON, G. See PARRILLI, G, CUOMO, R, et al.BUENO, L. See FREXINOS, J, FIORAMONTI, j, et al.

See SAGRADA, A, FARGEAS, M j, et al.BUKHAVE, K. See LAURITSEN, K, LAURSEN, L S, et al.BULGIM, O R. See MANNING, A P, BULGIM, O R, et al.BULLIMORE, D: Variceal bleeding: does variable delay in trial entry

invalidate comparison between trials?, 653BURGET, D W. See JONES, D B, HOWDEN, C W, et al.BURHOL, P G. See JORDE, R, BURHOL, P G, et al.BURLAND, W L. See DEAKIN, M, GLENNY, H P, et al.BURNHAM, W R. See O'BRIEN, J D, THOMPSON, D G, et al.BURY, R F. See BLOODWORTH, L L, STEVENS, P E, et al.BUTLER, R: 14C triolein breath test (Letter), 1320BUTLER, T, DAHMS, B, LINDPAINTNER, K, ISLAM, M, AZAD, M A K, andANTON, P: Segmental necrotising enterocolitis: pathological andclinical features of 22 cases in Bangladesh, 1433

BYTH, K. See NASIRY, R W, MCINTOSH, J H, et al.

Cal9-9, immunohistochemical expression in primary colonic polyps

General index

and polyps synchronous with colorectal cancer, 594; (Reprint),1049

Calcium binding protein, 10000 molecular weight, distributionalong small and large intestine of man, 878

, in vitro stimulation of pancreatic enzymc discharge by, 1215CAMILLERI M. See STANGHELLINI V, CAMILLERI M, et al.CAMPBELL, D. See AXON, A I R, BO'I'TRILL, PM, et al.CAMPBELL, G R. See MOOREHEAD, R J, CAMPBELL, 6 R, et al.Carbohydrate salvage by colon, impairment of, diarrhoea in ulccra-

tive colitis related to?, 1090Carbon dioxide and ginger as thromboxane synthetase inhibitors for

peptic ulceration (Letter), 1323CARBONE, F R. See KAGNOFF, M F, PATERSON, Y J, et al.Carcinoembryonic antigen, gastric, analysis of, as aid during screen-

ing for gastric neoplasia in atrophic gastritis, evaluation of, 26, serum concentration, fall after cytotoxic chemotherapy

for disseminated colorectal cancer, significance of, 1625Carcinogenesis, colonic, effect of long term lactulose ingestion on

secondary bile salt metabolism and potential protective effect oflactulose in, 675

,colorectal, dietary manipulation during, morphological andcell kinetic effects of, 754

,experimental, and proliferative instability at colonic anasto-moses, 808

, gastric, in precancerous conditions, nitrosamine hypothesis of,evaluation of, and urinary N-nitrosoproline excretion, 216

, intestinal, experimental, and enteroglucagon in rat, 33Carcinoid flush, cause of (Leading article), 1413-syndrome, bradykinin in, 1417

tumour of ampulla of Vater presenting as acute pancreatitis(Case report), 1296

tumours, gastric, achlorhydria and hypergastrinaemia as causalsequence for, reassessment of (Progress report), 488; (Letters),1189, 1191, 1319

Carcinoma after peptic ulcer surgery (Leading article), 921and dysplasia development in longstanding ulcerative colitis,

flow cytometric DNA analysis as method of prediction of, 1100, colonic, macrophage chemotaxis in, tumour related inhibition

of, 416, colorectal, anastomotic recurrence of, biological phenomenon

or avoidable calamity? (Leading article), 786; (Letter), 1691,disseminated, fall in serum CEA concentration after

cytotoxic chemotherapy for, significance of, 1625- , in ulcerative colitis (Letter), 917- ,polyps synchronous with, and primary colonic polyps,

immunohistochemical Cal9-9 in, 594; (Reprint), 1049gastric, gastric enzymes as screening test for, 319gastrointestinal, lymphokine activated killer cells in, 1420,- ,upper, diagnosis of, endoscopic needle aspiration

cytology in, 1142-, hepatocellular, primary, lysis of tumour cells by lymphokine-

activated killer cells in, 117immunotherapy with lymphokine-activated killer cells

(Leading article), 113, increased risk at multiple sites after gastric surgery for peptic

ulcer, 924, oesophageal, palliation for (Leading article), 781

Cardia, pneumatic dilatation of, 24 hour oesophageal acidity inachalasia before and after, 883

CAROLAN, G. See SAVAGE, A P, ADRIAN, T E, et al.CARR, K. See GALLOWAY, D J, JARRETT, F, et al.CARTER, D C: Cancer after peptic ulcer surgery (Leading article), 921CASTELLI, M. See SIMI, M, LEARDI, s, et al.Catecholamines, hepatic intestinal uptake and release in alcoholic

cirrhosis, evidence of enhanced hepatic intestinal sympatheticnervous activity in, 1637

Cation transport in colonic epithelium, acute effects of dexametha-sone, 701

CA-rTAN, D. See BELAICHE, J, ZIITOUN, J, et al.CAYGILL, C P J, HILL, M J, HALL, C N, KIRKHAM, J S, and NOR1'HFIELD, 'I' C:

General index 1697

Increased risk of cancer at multiple sites after gastric surgery forpeptic ulcer, 924

CECCHE1rI, l. See SCIARRE'rIA, C;, FAGIOLI, (i, et al.Cell mediated, antibody dependent cell mediated and humoral

cytotoxic responses, alterations during amoebic infcction inguinca pigs, 1251

Cerebral oedema, fulminant hepatic failure with, neurologicalsequelae in 2 patients recovered from (Case reports), 93

CHAKRABORTY, T K, BHATIA, D, HEADING, R C, and FORD, M J: Salicylateinduced exacerbation of ulcerative colitis (Case report), 613

CHAMBERS, J B, PRYCE, D, BlAND, J M, and NORTHFIELD, T C: Effect ofbedtime ranitidine on overnight gastric acid output and intra-gastric pH: dose/responsc study and comparison with cimetidinc,294

CHANG, K J. See HSIEH, K H, SHU, S, et al.CHAPMAN, R W. See DIXON, J M, CHAPMAN, R W, etal.CHARI, S. See SARIN, S K, NANDA, R, et al.CHA'i-1iRJEE, V K. See SAVAGE, A P, ADRIAN, I E, et al.CHAVES, M, SMITH, M w, and WILLIAMSON, R C N:' Increased activity of

digestive enzymes in ileal enterocytes adapting to proximal smallbowel resection, 981

CHAWLA, Y K. See DIl AWARI, J B, and CHAWILA, Y K

CHENG, J -I, and SHINOZUKA, K: Participation of prostaglandin E. inthe purinergic neurotransmission of gut, 1605

CHERIAN, L. See LAYER, P, HOIZ, J, et al.CHIA, J L S. See KANGi, J Y, WU, A Y 'I1, et al.CHINNERY, J B. See MORRIS, D L, CHINNERY, J B, et al.Chlamydia trachomatis, isolation from liver of patient with pro-

longed fever (Case report), 1514Cholangitis in AIDS (Case reports and review), 1653Cholecystectomy, flatulent dyspepsia after, intragastric bile acid

concentrations unrelated to, 131,symptoms after, and prospective study of gall stonc patients

before and 2 years after surgery, 1500Cholelithiasis, peptic ulceration, and dyspepsia of unknown cause,

clinical presentation of 221 patients and discriminant value ofdyspeptic symptoms, 40

Cholera, single dose tetracycline in (Cliniical trial), 1029Cholescintigraphy, clinical, gall bladder emptying in normal sub-

jects as data basc for, 137Cholestasis and liver failure with lambda-AL amyloidosis (Case

report), 903CHRISTENSEN, N J. See HENRIKSEN, J H, RING-LARSEN, H, et al.CHRISTIANSEN, J. See OLSEN, J A, LOUD, F B, et al.CHRISTIANSEN, L A. See JENSEN, S L, HC)LS'I', i J, et al.CHU, C T. See HSIF.H, K H, SHU, s, et al.CHU, K W. See LAU, W Y, FAN, S T, et al.CHURCH, H A. See COMPSTON, J E, JUDD, D, et al.CILLUFFO, T. See BAUERFEIND, P, CILLUFFO, '1, et al.Cimetidine and ranitidine, dose related in vitro effects on basal andACTH-stimulated steroidogenesis (Letters), 1688, 1690

bedtime, effect on overnight gastric acid output and intra-gastric pH, comparison with ranitidine, 294-in 2 different dosages versus tripotassium dicitrato bismuthatc

in treatment of resistant duodenal ulcers (Cliniical trial), 907Cirrhosis, alcoholic, hepatic intestinal uptake and release of

catecholamines in, evidence of enhanced hepatic intestinalsympathetic nervous activity in, 1637

,development in response to beta-blockade, changes in bloodflow, portal pressure and shunting during, 663

e,nhanced oral bioavailability of meptazinol in, 248of liver and non-cirrhotic portal fibrosis, measurement and

correlation of wedged hepatic, intrahepatic, intrasplenic andintravariceal pressures in, 260

Cisapride and placebo in treatment of chronic constipation (Clinicaltrial), 1033

,chronic administration of, effect on gastric emptying of solidmeal and dyspeptic symptoms in idiopathic gastroparesis, 300

effect on gastrointestinal transit of solid meal in normal humansubjccts, 13

-inhibition of effect of serotonin on rat ileal transport, evidencefor involvement of 5-HIT2 receptors in, 844

CIVIER, A. See BENNEIl-, A, CIVIER, A, et al.CLARK, C G. See BOWN, SC, HAWES, R, et al.ClARK, M L. See LUCEY, M R, CLARK, M L, et al.

See PATIL, D H, WESI ABY, D, et al.Cl.AVEt, F. See ROULOT, D, VALLA, D, et al.Clonidine, oral, for proctalgia fugax (Case report), 1039Cobalamin absorption, correlation with in vitro effect of duodenal

juice on R binders cobalamin complexes in pancreaticinsufficiency, 70

COCKEL, R: NSAIDs- should every prescription carry a GovernmentHealth Warning? (Leading article), 515

Coeliac disease among children in Kuwait, problems with diagnosisand management, 1595

and collagenous colitis (Letter), 364and pseudopolycythaemia (Case reports), 1041ccellular hypersensitivity to gluten derived peptides in, 426,impaired gall bladder contraction of, pathogenesis of,

1426,jejunal mucosa of children with, HLA-DR expression,

natural killer cells and IgE containing cells in, 988-, partially treated, steatorrhoea caused by, delayed mouth-

to-caecum transit of lactulose labelled liquid test meall in patientswith, 1275

, passage of dietary antigens into blood of children with,and quantification and size distribution of antigens, 1062

pathogenesis of, role of human intestinal adenovirus in,evidence for, 995

Colectomy and ileostomy, patient's reactions to, personal account,81

COLGAN, S M. See WHORWFLL, P J, PRIOR, A, et at.Colitis and oesophageal ulceration due to cytomegalovirus in AIDS,

clinical manifestations and treatment with Foscarnet (Casereports), 482

collagenous, and coeliac disease (Letter), 364in Greece (Letter), 230

eosinophilic, case of (Letter), 506ischaemic, acute, bloody diarrhoea in female long distance

runner due to (Case report), 896,pseudomembranous, epidemic of, importance of person to

person spread in, 1467ulcerative, active, increased arachidonic acid composition of

phospholipids in colonic mucosa in, 1002AIDS-related Kaposi's sarcoma presenting as, and com-

plicated by toxic megacolon (Case report), 1302and Crohn's disease of colon, local IgA subclass altera-

tions in. 1013c,hronic, in community, prognosis of, 1261,colonic bacterial proteases to IgA, and sIgA in, 186;

(Letter), 917colorectal carcinoma in (Letter), 917comparison of sodium cromoglycate enemas with pre-

dnisolone enemas in treatment of (Clinical trial), 88; (Letter),1323

,- ,diarrhoea in, related to impaired colonic salvage ofcarbohydrate?, 1090

DNA aneuploidy in (Letters), 642, 643,exacerbation of, induced by salicylate (Case reports),

613,faecal recovery of ingested 5-amino salicylic acid in,

effect of polymer coating, 1084gastrointestinal transit in, influence of olsalazine, 1474,in Jewish population of Southern Israel (1961-85),

epidemiological and clinical study, 1630,incidence and prevalence in residents of Rochester,

Minnesota ( 1960-79), 402,longstanding, flow cytometric DNA analysis in, as

method of prcdiction of dysplasia and carcinoma development,1100

1698 General index

, prostaglandin and leucotriene production in, in vivoeffects of oral prednisolone, 1095

,-seminal abnormalities induced by sulphasalazine in,effect of mesalazine substitution, 1008

Collagenous colitis and coeliac disease (Letter), 364in Greece (Letter), 230

Colon, anastomoses, proliferative instability and experimentalcarcinogenesis at, 808-, bacterial proteases to IgA, and sIgA in ulcerative colitis, 186;

(Letter), 917,carbohydrate salvage by, impairment of, diarrhoea in ulcera-

tive colitis related to?, 1090, carcinogenesis, effect of long term lactulose ingestion on

secondary bile salt metabolism and potential protective effect oflactulose in, 675

, carcinoma of, macrophage chemotaxis in, tumour relatedinhibition of, 416

, Crohn's disease of, and ulcerative colitis, local IgA subclassalterations in, 1013

,epithelium, cation transport in, acute effects of dexametha-sone, 701

microbial metabolism, effect of changing transit time, 601motility, reduction by intravenous nicardipine in irritable

bowel syndrome, 1609, motor activity in healthy subjects, 24-hour manometric

recording, 17complexes, effects of oral laxatives in dogs, 1112

mucosa of, cell suspensions of, phagocytes in, 976phospholipids in, increased arachidonic acid com-

position in active ulcerative colitis, 1002, myoelectrical activity in painless diarrhoea of irritable bowel

syndrome, 1613,polyps of, primary, and polyps synchronous with colorectal

cancer, immunohistochemical Cal9-9 in, 594; (Reprint), 1049Colonic epithelial dysplasia in inflammatory bowel disease, colono-

scopy screening for, 1489Colonoscopy, future requirements in Britain for, 772; (Letter), 1322

screening for colonic epithelial dysplasia in inflammatory boweldisease, 1489

Colorectal carcinogenesis, dietary manipulation during, morpho-logical and cell kinetic effects of, 754

carcinoma, anastomotic recurrence of, biological phenomenonor avoidable calamity? (Leading article), 786; (Letter), 1691

,disseminated, fall in serum CEA concentration aftercytotoxic chemotherapy for, significance of, 1625-in ulcerative colitis (Letter), 917-, polyps synchronous with, and primary colonic polyps,

immunohistochemical Cal9-9 in, 594; (Reprint), 1049neoplasia, experimental, plasminogen activators in, role in

adenoma-carcinoma sequence?, 816, relationship to duodenal bile acids, 1454

Complement fixing antibodies against lipopolysaccharides from Ecoli, absence in subgroup of patients with Crohn's disease, 1460

COMPSTON, J E, JUDD, D, CRAWLEY, E 0, EVANS, W D, EVANS, C, CHURCH,H A, REID, E M, and RHODES, J: Osteoporosis in patients withinflammatory bowel disease, 410

Computers, value to clinician in gastroenterology (Leading article),373

Confidence intervals in reporting of clinical trials, need for (Letters),916, 1549

CONNELL, J M C. See KENYON, C J, FRASER, R, et al.CONNOLLY, C E. See BREEN, E G, FARREN, C, et al.Constipation, chronic, treatment with cisapride and placebo

(Clinical trial), 1033,spontaneous and induced, irritable bowel-type symptoms in,

156CONTEAS, C N. See DUBICK, M A, COTEAS, C N, etal.Continence, faecal, preservation during rises in intraabdominal

pressure, role for flap valve in?, 1242COOK, A R. See THOMAS, J M, MISIEWICZ, iJ, et al.

COOKE, T. See SAVAGE, A P, MATTHEWS, J L, et al.COONEY, C. See NOILAN, N P M, KELLY, C P, et al.CORINALDESI, R, Sl'ANGHELLINI, V, RAI'I'I, C, REA, E, SAtGEMINI, R, and

BARBARA, L: Effect of chronic administration of cisapride ongastric emptying of a solid mealtand on dyspeptic symptoms inpatients with idiopathic gastroparesis, 300

Corrections, 366, 780COSTANTINI, F M. See SIMI, M, LEARDI, s, et al.cox, J, and BENNEFI-, J R: Light at the end of the tunnel? Palliation for

oesophageal carcinoma (Leading article), 781CRAMPTON, J R, GIBBONS LC, and REES, W D W: Effect of luminal plI on

the output of bicarbonate and PGE, by the normal humanstomach, 1291

,TOBIN, M v, and MCCONNELL, R B: Pseudopolycythaemia andcoeliac disease (Case reports), 1041

CRAWLEY, E O. See COMPSTON, J E, JUDD, D, et al.C-reactive protein and serum phospholipase A, in assessment of

severity of acute pancreatitis, 764CREAN, G P. See MCCOLL, K E L, BUCHANAN, N M M, et al.

See MCLAUCHLAN, G, RAWLINGS, J M, et al.CREED, F, and GUTHRIE, E: Psychological factors in the irritable bowelsyndrome (Progress report), 1307

CREUTZFELDT, W. See BORDI, C, CREUTZFELDl', w, et al.CRITCHLEY, M. See BAXTER, J N, GRIME, J S, et al.-. See PARR, N J, GRIME, J S, et al.Crohn's disease, absence of complement fixing antibodies against

lipopolysaccharides from E coli in subgroup of patients with, 1460-, activation of peripheral blood and intestinal lamina

propria lymphocytes defined by expression of early activationantigens in, 745

, fertility in, European study (Letter), 112in Netherlands, immunoglobulin allotypes in, 610life prospects and quality of life in, 382neuromuscular and vascular hamartoma of small

intestine as form of (Case reports), 1663-of colon and ulcerative colitis, local IgA subclass altera-

tions in, 1013-of small bowel, active, abnormal lactulose/rhamnose

permeability in, improvement by elemental diet, 1073quality of life in (Leading article), 378raised plasma platelet factor 4 concentrations in, 336severe, effective intravenous cyclosporin therapy in

patient on parenteral nutrition (Case report), 1166, severity and activity in, observer variation in calculating

indices of (IOIBD report no 1), 474with respiratory tract involvement (Case reports), 1669

CROSSLING, F T. See ALLAM, B F, TILLMAN, J E, et al.CROWE, J. See BARDHAN, K D, IHOMPSON, M, et al.CROWE, S M. See BIGGS, B A, CROWE, S M, et al.CULLEN, A. See AFDHAL, N H, LONG, A, et al.CUMMINGS, J H, POMARE, E W, BRANCH, W J, NAYLOR, C P E, andMACFARLANE, G T: Short chain fatty acids in human large intestine,portal, hepatic and venous blood, 1221

See also STEPHEN, A M, WIGGINS, H s, et al.CUNNINGHAM, J A. See AMMON, H V, FOWLE, S A, et al.CUOMO, R. See PARRILLI, G, CUOMO, R, et al.CUSCHIERI, A. See MACKIE, C R, BAXTER, J N, etal.CUVELIER, C, BARBA'I'IS, C, MIELANTIS, H, DE VOS, M, ROELS, H, and VEYS,

E: Histopathology of intestinal inflammation related to reactivearthritis, 394

Cyclosporin therapy, intravenous, effective use in patient withsevere Crohn's disease on parenteral nutrition (Case report), 1166

CYNK, E U. See MAXTON, D G, CYNK, E U, et al.Cyst, periampullary, as surgically remediable cause of pancreatitis

(Case reports), 358Cystic fibrosis as gastroenterological 'cornucopia' (Progress report),

1531-t bile acid secretion in (Letter), 506

Cysts, hydatid, albendazole sulphoxide penetration into, 75Cytomegalovirus colitis and oesophageal ulceration in AIDS,

General index 1699

clinical manifestations and treatment with Foscarnet (Casereports), 482

[)AGAY, F. See LEMANN, M, MESSING, B, et at.DAHMS, B. SeeBU'IJLER, 1, DAHMS, B, et al.DALY, I M. See ALLEN-MERSH, 'I' X, KEMENY, N, et al.DAMKJ,ER-NIEL SEN, M. SeeSZECSI, PB, HALGREEN, H, et al.DAN, M, IYRREILL, L D i, and GOLDSAND, G: Isolation of Chlamydia

trachoinatis from the liver of a patient with prolonged fcver (Casereport), 1514

DAS, U N, REDDY, D N, RAO, P N, and RADHA, v: Essential fatty acidsand peptic ulcer disease (Letter), 914

DAVIDSON, G P, and ROBB, T A: Bile acid secretion in cystic fibrosis(Letter), 506

DAVIES, J G. See WALT, R P, KEMP, R i', et al.DAVISON, 1'. See BANNISIER, J J, DAVISON, P, et al.DAWSON, A M. See LUCEY, M R, CLARK, M L, etal.

See PA'I'IL, D H, WESIABY, D, et al.DAY, S J. See KENDALL, G P N, 'I1HOMPSON, D G, et al.Dazmegrel in selective inhibition of thromboxane synthesis for

gastric mucosal protection, 541DEAKIN, M, GLIENNY, H P, RAMAGE, J K, MILLS, J G, BURLAND, W 1., and

WILt IAMS, J (: Large single daily dose of histamine H2 receptorantagonist for duodenal ulcer: how much and when'?: a clinicalpharmacological study, 566

DEBNAM, E S. See MAZZANII, R, DEBNAM, ES, et al.DE CAES'I'ECKER, J S, BLACKWELL, J N, PRYDE, A, and HEADING, R C:Daytime gastro-oesophageal reflux is important in oesophagitis,519

DE DOMBAL, F'1': Back to the future; or forward to the past'? (Leadingarticle), 373

,and SOFI'LEY, A: IOIBD report no 1: observer variation incalculating indices of severity and activity in Crohn's disease, 474

Defecation, effect of stool size and consistency, 1246DEGO'101, C. See ROULO'I', D, VALILA, D, et al.DEIGH'ION, C M. See AL MARDINI, H, LINDSAY, DC, et al.DELLADEl'SIMA, A. See ARCHIMANDRIIIS, A, IZIVRAS, M, et al.De-Nol and sucralfate, gastrocytoprotection by, and role of endo-genous prostaglandins, 201; (Letter), 1322

stimulation of gastric and duodenal alkaline secretion throughprostaglandin dependent mechanism, 1557

-versus 2 different dosages of cimetidine in treatment ofresistant duodenal ulcers (Clinical trial), 907

Dermatitis herpetiformis, gastritis associated with, and simplegastritis, difference in local immunoglobulin production between,1589

DE VOS, M. See CUVELIER, C, BARBA'I'IS, C, et al.Dexamethasone, acute effects on cation transport in colonic

epithelium, 701DIAMANT, N E. See MCHUGH, S M, and DIAMAN'I', N E

Diaphragmatic contraction, effect on lower oesophageal sphincterpressure, 1564

Diarrhoea, bloody, due to acute ischaemic colitis in female longdistance runner (Case report), 896

, functional, bile acid malabsorption in, detection of,75SeHCAT test results and corrclation with small bowel transit,970

in ulcerative colitis related to impaired colonic salvage ofcarbohydrate'?, 1090

,painless, of irritable bowel syndrome, colonic myoclectricalactivity in, 1613

Diet, elemcntal, improvement of abnormal lactulose/rhamnosepermeability in active Crohn's discase of small bowcl by, 1073

inert bulk and dietary fibre, effects on response ofintestinal epithelium to refeeding in rat and relationship to plasmagastrin, enteroglucagon, and PYY concentrations, 171

Dietary antigens, passage into blood of coeliac children, andquantification and size distribution of antigens, 1062-macromolecules, intestinal absorption, possible role in disease(Leaditig article), 1057

manipulation during colorectal carcinogenesis, morphologicaland cell kinetic effects of, 754

Diets, enteral, 2, jejunal water and electrolyte absorption from,importance of sodium content in, 681

,liquid, 'elemental' and 'complete', small intestinal response inrat to, effect of dietary bulk, 688

Digestive enzymes, increascd activity in rat ileal enterocytes adapt-ing to proximal small bowel resection, 981

tract. See Gastrointestinal tractDILAWARI, J B, and CHAWLA, Y K: Spontaneous (natural) spieno-

adrenorenal shunts in extrahepatic portal venous obstruction: aseries of 20 cases, 1198

DI MARIO, F. See BAYrAGLIA, G, DI MARIO, F, et al.DIXON, J M, CHAPMAN, R W, and BERRY, A R: Carcinoid tumour of theampulla of Vater presenting as acute pancreatitis (Case report),1296

DIXON, M F. See FOZARD, J B J, QUIRKE, P, etal.S.ee MANNING, A P, BULGIM, 0 R, et al.

DNA analysis with flow cytometry in longstanding ulcerative colitisas method of prediction of dysplasia and carcinoma development,1100

ancuploidy in ulcerative colitis (Letters), 642, 643DONAILD)SON, I D. See MOOREHIAI), R J, CAMPBEI I., G R, et al.DRIVER, H E. See GELISTER, J S K, ILEWIN, M R, et al.DROZDOWICZ, D. See KON'I'UREK, S J, RADECKI,'r, et al.DUBICK, M A, CONTEAS, C N, BIlltY, Hi r, MAJUMDAR, A l' N, and GEOKAS,M C: Raised serum concentrations of pancreatic enzymes incigarette smokers, 330

Dubin-Johnson, Gilbert's and Rotor's syndromes, porphyrin meta-bolism in (Letters), 1548, 1549

Duodenal and gastric alkaline secretion stimulated by Dc-Nolthrough prostaglandin dependent mechanism, 1557

polyps in familial adenomatous polyposis, nature andprevalence, 306

pseudomelanosis, clinical and ultrastructural studies in (Casereports), 1673

Duodenum, bile acids in, relationship to colorectal neoplasia, 1454,juice, in vitro effect on R binders cobalamin complexes in

pancreatic insufficiency, correlation with cobalamin absorption,70

ulcer, acid supprcssion in, meta-analysis defining optimaldosing with antisecretory drugs for, 1120

, antral gastrin and somatostatin release in anaesthetised,atropinised patients with, effect of intragastric pH, 206

,-chronic, prognosis and effects of demographic andenvironmental factors and ulcer healing, 533

, gastric alkaline secretion in, vagal cholinergic control of,739; (Letters), 1687

histamine H.-receptor antagonist (cimetidine) in largesingle dose for, size of dose and timing, clinicopharmacologicalstudy, 566

,multiple, natural history and pathophysiology, 1134refractory, healing of, combined anti-muscarinic and H,

receptor blockade in, 1505, resistant, tripotassium dicitrato bismuthate versus 2

different dosages of cimetidine in treatment of (Ctlinical trial),907

, smokers and non-smokers with and without, comparisonof maximal gastric secretion in, 557

, transdermal scopolamine and gastric acid secretion in(Letters), 1686, 1687

Dyspepsia, flatulent, in patients with and without gallbladderdisease and postcholecystectomy, intragastric bile acid concentra-tions unrelated to, 131

-of unknown cause, peptic ulceration, and cholelithiasis, clinicalpresentation of 221 patients and discriminant value of dyspepticsymptoms, 40

Dyspeptic symptoms and gastric emptying of solid meal in idio-pathic gastroparesis, effect of chronic cisapride administration,300

1700

Dysphagia, malignant, advanced, endoscopic Nd YAG laser pallia-tion for, 799

, palliative Nd YAG laser therapy for, 792Dysplasia and carcinoma development in longstanding ulcerative

colitis, flow cytometric DNA analysis as method of prediction of,1100

EASTWOOD, J. See FORD, M J, MILLER, P MCC, et al.EASTWOOD, M A. See FORD, M J, MILLER, P MCC, et al.EDDLESI'ON, A L W F. See FAGAN. E A, and EDDLESION, A L W F

EDGE, C. See SPILLER, R C, ILEE, Y C, et al.EDWARDS, C A, HOt.DEN, S, BROWN, C, and READ, N W: Effect of

cisapride on the gastrointestinal transit of a solid meal in normalhuman subjects, 13

EGAMI H. See SAKAMOIO, K, HAGA, Y, et al.EINARSSON, K, ANGELIN, B, and JOHANSSON, C: Biliary lipid meta-

bolism in chronic pancreatitis: influence of steatorrhoea, 1495EKSTROM, G. See TAGESSON, C, TELEMO, E, et al.Electrodes for 24 hour pH monitoring of upper gastrointestinal

tract, comparative study of, 935Electrolyte and water absorption, jejunal, from 2 enteral feeds,

importance of sodium content in, 681ELGJO, K. See VALNES, K, BRANDT/AEG, P, et al.ELMGREEN, J. See NIELSEN, O H, AHNFELT-R0NNE. I, etal.EL OMAR, E. See MCCOLL, K E L, [HOMPSON, G G, et al.ELSBORG, L. See JORGENSEN, F, HESSE, B, et al.EMDE, C, GARNER, A, and Bl.UM, A L: Technical aspects of intraluminalpH-metry in man: current status and recommendations (Progressreport), 1177

See also BAUERFEIND, P, CILLUFFO, ', et at.Emphysematous gastritis after acute pancreatitis (Case report), 900Encephalopathy, hepatic, comparative modes of action of lactitoland lactulose in treatment of, 255

, portal systemic, chronic, update 1987 (Progress report), 1043Endocrine adrenal tumour, mixed, causing steatorrhoea (Case

report), 1298Endoscopic needle aspiration cytology in diagnosis of upper gastro-

intestinal cancer, 1142Nd YAG laser palliation for advanced malignant dysphagia,

799sclerotherapy using absolute alcohol (Letter), 777sphincterotomy and surgical approaches in treatment of 'sump

syndrome', 142Endoscopy staffing and administration in England and Wales,

results of questionnaire (BSG Working Party report), 1527units, staffing of (BSG Working Party report), 1682

Enterocolitis, necrotising, segmental, pathological and clinicalfeatures of 22 cases in Bangladesh, 1433

Enterocyte function in progressive systemic sclerosis as estimated bydeconjugation of pteroyltriglutamate to folic acid, 435

turnover in rat small intestine, effect of chronic ethanolingestion, 52

Enterocytes, ileal, rat, adapting to proximal small bowel resection,increased activity of digestive enzymes in, 981

Enteroglucagon and experimental intestinal carcinogenesis in rat, 33Enteropathy, protein losing, due to intestinal schistosomiasis (Case

report), 616Eosinophilic colitis, case of (Letter), 506Epithelial. See IntraepithelialEscherichia coli, enteropathogenic, intestinal damage by, mecha-nism of, organ culture of rabbit ilcum as model for investigationof, 1283-, lipopolysaccharides from, complement fixing antibodies

against, absence in subgroup of patients with Crohn's disease,1460

ESTEVE, M, and GASSULL, M A: Intestinal permeability and statistics(Letter), 777

Ethanol consumption, long term, antecedent, combined with differ-ent diets, alteration of severity of experimental acute pancreatitisin rats by, 64

General index

damage, acute, rat gastric epithelium recovering from, forma-tion of fibrin based gelatinous coat over, and interaction withadherent mucus, 835

ingestion, chronic, effect on enterocyte turnover in rat smallintestine, 52

on lactase activity and active galactose absorp-tion in rat small intestine, 56

EVANS, B K. See MYERS, B, EVANS, D N W, et al.EVANS, C. See COMPSION, J E, JUDD, D, et al.EVANS, D. See LAMONT, G, EVANS, D, et al.EVANS, D F. See SMART, H L, FOSTER, P N, et al.EVANS, D N W. See MYERS, B, EVANS, D N W, et al.EVANS, W D. See COMPSTON, J E, JUDD, D, et al.Exercise, effect on mesenteric blood flow, 583

Faecal continence preservation during rises in intraabdominalpressure, role for flap valve in'?, 1242

excretion of ca,-antitrypsin and .I..n-labelled granulocytes inassessment of disease activity in chronic inflammatory boweldiseases, 386

recovery of ingested 5-amino salicylic acid in ulcerative colitis,effect of polymer coating, 1084

FAGAN, E A, and EDDLESTON, A L W F: Immunotherapy for cancer: theuse of lymphokine activated killer cells (Leadin,g artictle), 113

FAGIOLI, G. See SCIARRErI-'A, C;, FAGIOLI, G, et al.FAIS, s. See PALLONE, F, FAIS, S, et al.FAN, S T. See LAU, W Y, FAN, S'il, et al.FARGEAS, M J. See SAGRADA, A, FARGEAS, M J, et al.FARINAII, F. See BA'I-I'AGLIA, G, Di MARIO, F, et al.FARREN, C. See BREEN, E G, FARREN, C, et al.FARWANA, S S. See KHUFFASH, F A, BARAKAI, M H, et at.Fat malabsorption, diagnosis of, 4C-triolein absorption test in, 694Fatty acids, essential, dietary, and decline in peptic ulcer disease

(Letters), 914, 915, short chain, in human largc intestine and portal, hepatic

and venous blood, 1221FAUSA, O. See VALNES, K, BRAND'I'ZAEG, P, et al.FAUST, H. See MARBET, U A, SlAltDER, G A, et al.Feeds. See DietsFELDMAN, M. See RICHARDSON, C r, and FELDMAN, M

FELLOWS, I w. See TURNER, J M, LAWRENCE, S, et al.FERGUSON, D J P. See GEBBERS, J-O, FERGUSON, D J P, et al.FERMOR, B. See ROE, R, FERMOR, B, et al.Fertility in Crohn's disease, European study (Letter), 112Fever, prolonged, isolation of Chlarnvdia trachoinatis from liver of

paticnt with (Case report), 1514FILIPOWIC7, B. See WAL'l, R P, KEMIP, R 'i1, et al.FIMMEIL, C J. See BAUERFEIND, P, CILLUFFO, T, et al.FINCH P J, RYAN, F P, ROGERS, K, and HOL'I', S: Gastric enzymes as a

screening test for gastric cancer, 319FIORAMONTI, J. See FREXINOS, J, FIORAMONTI, J, et al.FISCHBACH, W, BECKER, W, MOSSNFR, J, KOCH, w, and REINERS, C:

Faecal alpha-I -antitrypsin and excretion of "' Indium granulocytesin assessment of disease activity in chronic inflammatory boweldiseases, 386

FLEMING, J. See MCLAREN, M, BRAYE, S, etal.Flow cytometric DNA analysis in longstanding ulcerative colitis asmethod of prediction of dysplasia and carcinoma development,1100

FLOWERDEW, A D S, RICHARDS, H K, and TAYLOR, i: Temporary bloodflow stasis with degradablc starch microspheres for liver meta-stases in a rat model, 1201

FOGED, N. See HUSBY, S, FOGED, N, et al.FOLTMANN, B. See SZECSI, P B, HALGREEN, H, et al.Food consistency, effect on gastric emptying, 1584FORBES, A, PORTMANN, B, JOHNSON, P, and WIl iIAMS, R: Hepaticsarcomas in adults: a review of 25 cases, 668

FORD, M J, MILLER, P MCC, EAS-I1WOOD, J, and EASTWOOD, M A: Lifcevents, psychiatric illness and the irritable bowel syndrome, 160

See also CHAKRABORTY, '1I K, BHAIIA, D, et al.

General index

FORSTER, J K. See THOMAS, J M, MISIEWICZt, J J, etal.FORS'I'ER, S. See WEBER, J N, THOM, S, et al.Foscarnet treatment of cytomegalovirus colitis and oesophageal

ulceration in AIDS (Case reports), 482FOSTER, P N, STEWART, M, LOWE, i S, and ATKINSON, M: Achalasia like

disorder of the oesophagus in von Recklinghausen's neurofibro-matosis (Case report), 1522

See also SMART, H L, FOSrER, P N, et al.FOWLE, S A. See AMMON, H V, FOWLE, S A, et al.FOZARD, I B J, QUIRKE, P, and DIXON, M F: DNA aneuploidy in

ulcerative colitis (Letter), 642FRANK, W O. See KARLSIADI, R G, FRANK W O, et al.FRAN7FN, t.. See OTAMIRI, T, FRANZEN, L, et al.

FRASER, D. See ODES, H S, FRASER, D, et al.FRASER, R. See KENYON, CJ, FRASER, R, etal.FREXINOS, J, FIORAMONII, J, and BUENO, L: Colonic myoclectrical

activity in lBS painless diarrhoea, 1613FROS1, A G. See SARRE, R G, FROS'I', A G, et al.FUJISHIMA, M. See NISHIDA, R, MIWA, H, etal.FUJIYAMA, Y. See SENDA, S, FUJIYAMA, Y, et al.FURNO, A. See SCIARRETTA, G, FAGIOLI, G, et al.

GABURRI, M. See NARDUCCI, F, BASSO'rII, G, et al.GAFFNEY, P J. See GELISTER, I S K, ILEWIN, M R, et al.GAII, J E. SeeBARDHAN, K D, -I'HOMPSON, M, et al.Galactose absorption, active, and lactase activity in rat small

intestine, effect of chronic ethanol ingestion, 56GALANOS, C. See ZEITZ, M, HOPF, U, et al.Gall bladder contraction, impaired, of coeliac disease, pathogenesis

of, 1426disease, flatulent dyspepsia in patients with and without,

intragastric bile acid concentrations unrelated to, 131emptying in normal subjects as data base for clinical

cholescintigraphy, 137relationship to gastric emptying of solid meal before

and after vagotomy, 855-stone patients, postcholecystectomy symptoms and prospective

study before and 2 years after surgery, 1500stones, electrohydraulic lithotripsy of, in vitro and animal

studies, 267GALLOWAY, D J, JARRETT, F, BOYL E, P, INDRAN, M, CARR, K, OWEN, R W,

and GEORGE, W D: Morphological and cell kinetic effects of dietarymanipulation during colorectal earcinogenesis, 754

GARNER, A. See EMDE, C, GARNER, A, et al.GARVIE, N. See KENDAILL, G P N, THOMPSON, D G, et al.GASSER, i. See BAUERFEIND, P, CILLUFFO, T, et al.GASSULL, M A. See ESTEVE, M, and GASSULL, M A

Gastric acid and pancreatic polypeptide responses to modified shamfeeding, effects of truncal and parietal ccll vagotomy, 280

output and intragastric pH, overnight, effect of bedtimeranitidine, dose/response study and comparison with cimetidine,294

secretion and gastrin release, effect of nifedipine, 455and transdermal scopolamine in duodenal ulcer

(Letters), 1686, 1687, relationship to infection (Progress report), 96stimulated by meal, inhibition by SMS 201-995, 464

alkaline secretion in normal subjects and in duodenal ulcer,vagal cholinergic control of, 739; (Letters), 1687

and duodenal alkaline secretion stimulated by De-Nol throughprostaglandin dependent mechanism, 1557

polyps in familial adenomatous polyposis, nature andprevalence, 306

carcinogenesis in precancerous conditions, nitrosaminehypothesis of, evaluation of, and urinary N-nitrosoprolineexcretion, 216

-carcinoid tumours, achlorhydria and hypergastrinaemia ascausal sequence for, reassessment of (Progress report), 488;(Letters), 1189, 1191, 1319CEA analysis as aid during screening for gastric neoplasia in

1701

atrophic gastritis, evaluation of, 26contents, effects of 1 year's ranitidine treatment and truncal

vagotomy, 726cytoprotection by colloidal bismuth subeitrate (De-Nol) and

sucralfate and role of endogenous prostaglandins, 201; (Letter),1322

distension and vagal stimulation in ferrets, intragastric pressureresponses to, effects of partial truncal vagotomy, 1569

emptying, effect of food consistency, 1584of solid meal and dyspeptic symptoms in idiopathic gastro-

paresis, effect of chronic cisapride administration, 300, relationship to gall bladder emptying

before and after vagotomy, 855enzymes as screening test for gastric cancer, 319epithelium, rat, recovering from acute ethanol damage, forma-

tion of fibrin based gelatinous coat over, and interaction withadherent mucus, 835

mucosa in portal hypertension (Letter), 1324mucosal protection with selective inhibition of thromboxane

synthesis by dazmegrel, 541mucus glycoprotein, molecular weight of, as predeterminant of

degree of aspirin induced chronic gastric ulceration in rat, 287-secretion, maximal, comparison in smokers and non-smokerswith and without duodenal ulcer, 557

surgery for peptic ulcer, cancer after (Leading article), 921- ,increased risk of cancer at multiple sites

after, 924ulcer, bile reflux equal in healthy controls and in patients with,

1577relapse, ranitidine 150 mg at night in prevention of, 460

-, slow healing and relapsing, clinical markers of, 210See also Intragastric; Stomach

Gastrin and somatostatin, antral release in anaesthetised,atropinised duodenal ulcer patients and controls, effect of intra-gastric pH, 206

-release and gastric acid secretion, effect of nifedipine, 455Gastrin-releasing peptide, origin of gastrin liberated by, 1128Gastritis associated with dermatitis herpetiformis and simple

gastritis, difference in local immunoglobulin production between,1589

,atrophic, gastric CEA analysis as aid during screening forgastric neoplasia in, evaluation of, 26

emphysematous, after acute pancreatitis (Case report), 900erosive, relationship to acid secreting area and intestinal

metaplasia, and trial of healing effect of pirenzepine, 561;(Letters), 1321, 1322

-, hypertrophic, giant, familial (Menetrier's disease) (Casereport), 1517

Gastroduodenal brake and small bowel resistances, 950Gastroenterological disorders, functional, identification of (Leading

article), 1; (Letter), 776Gastrointestinal cancer, lymphokine activated killer cells in, 1420

, upper, diagnosis of, endoscopic needle aspirationcytology in, 1142

haemorrhage, obscure, specialist investigation of, 47, of obscure origin, preoperative and intraoperative locali-

sation of, 869tissues, normal and malignant, human. arachidonate and

metabolites extracted from, measurement of, 315tract, 5-amino salicylic acid released at different sites in,

metabolism and urinary excretion in healthy volunteers, 196- diseases, tumour diagnostics in, comparative effectiveness

of CA 19-9, CA 125 and CEA, 323,human, vitamin B12 R-binder in, immunohistochemical

localisation of, 339intraluminal pH monitoring, technical aspects, current

status and recommendations (Progress report), 1177, nature and functions of (Leading article), 650

-purinergic neurotransmission, prostaglandin E2 participa-tion in, 1605

1702 General index

-, upper, motility, modulation by rectal distension, 864,-pH monitoring, 24 hour, comparative study of

electrodes for, 935transit in ulcerative colitis, influence of olsalazine, 1474

of solid meal in normal human subjects, effect ofcisapride, 13-time in rat, measurement of, adaptation of hydrogen

analysis for, 849, upper, action of centrally mediated autonomic stimula-

tion, comparative study of 2 stimuli, 960-. See also Mouth-to-caecum transit

Gastro-oesophageal reflux. See Reflux, gastro-oesophagealGastroparesis, idiopathic, gastric emptying of solid meal and

dyspeptic symptoms in, effect of chronic cisapride administration,300

GAZZARD, B G: The quality of life in Crohn's disease (Leading article),378

GEBBERS, J-O, FERGUSON, D J P, MASON, C, KELLY, P, and JEWELL, D P:Spirochaetosis of the human rectum associated with an intra-epithelial mast cell and IgE plasma cell response, 588

GELISTER, J S K, LEWIN, M R, DRIVER, H E, SAVAGE, F, MAHMOUD, M,GAFFNEY, P H, and BOULOS, P B: Plasminogen activators inexperimental colorectal neoplasia: a role in the adenoma-carcinoma sequence?, 816

GENT, A E. See GRACE, R H, GENI, A E, et al.GEOKAS, M C. See DUBICK, M A, CONTEAS, C N, etal.GEORGE, W D. See GALLOWAY, D J, JARRE'Il-l, F, et al.GEORGIOU, G. See MORRIS, D L, CHINNERY, J B, et al.GERTSCH, P, and MEISTER, J-J: Pressure measurement in oesophageal

varices: preliminary report on a new non-invasive method, 1162GHATEI, M A. See GOODLAD, R A, LENTION, W, et al.

See SAVAGE, A P, MATTHEWS, J L, et al.GIBBONS, C. See BANNISTER, J J, DAVISON, P, et al.

See BANNISrFER, J J, GIBBONS, C, et al.GIBBONS, L C. See CRAMPTON, J R, GIBBONS, L C, et al.GIBSON, P R. See HERMANOWICZ, A, GIBSON, P R, et al.GIBSON, R N. See GUPTA, S, BARTER, S, et al.GIESE, J. See GUSTAFSEN, J, BOESBY, s, et al.GILBERT, L M. See ALLAM, B F, TILLMAN, J E, et al.Gilbert's syndrome, and Dubin-Johnson and Rotor's syndromes,

porphyrin metabolism in (Letters), 1548, 1549, porphyrin metabolism and haem biosynthesis in, 125

GILES, G R. See MONSON, J R T, RAMSDEN, c w, et al.GILL, R C, KELLOW, J E, and WINGATE, D L: Gastro-oesophageal reflux

and the migrating motor complex, 929See also KELLOW, J E, GILL, R C, et al.See also WINGATE, D L, and GILL, R C

GILMOUR, H M. See BISHOP, P E, MCMILLAN, A, et al.GIMSON, A E S. See GUARNER, F, HUGHES, R D, et al.Ginger and carbon dioxide as thromboxane synthetase inhibitors for

peptic ulceration (Letter), 1323GIRDWOOD, A H. See KALVARIA, 1, BORNMAN, P C, et al.GLENNY, H P. See DEAKIN, M, GLENNY, H P, etal.Gluten, peptides derived from, cellular hypersensitivity to, in

coeliac disease, 426Glycoprotein, gastric mucus, molecular weight of, as predeter-minant of degree of aspirin induced chronic gastric ulceration inrat, 287

GOEBELL, H. See LAYER, P, HOIZ, J, etal.GOLDBERG, A. See MCCOLL, K E L, THOMPSON, G G, et al.GOLDSAND, G. See DAN, M, 'I'YRRELL, L D J, et al.GOLEMATIS, B. See MORRIS, D L, CHINNERY, J B, et al.GOODLAD, R A, LEN FON, W, GHATEI, M A, ADRIAN, T E, BLOOM, S R, and

WRIGHT, N A: Effects of an elemental diet, inert bulk and differenttypes of dietary fibre on the response of the intestinal epitheliumto refeeding in the rat and relationship to plasma gastrin,enteroglucagon, and PYY concentrations, 171

,WILSON, 'r J G, LENTON, W, GREGORY, H, MCCULLAGH, K G, andWRIGHT, N A: Intravenous but not intragastric urogastrone-EGF istrophic to the intestine of parenterally fed rats, 573

GOODMAN, M J. See RILEY, S A, LECARPEN1IER, J, et al.GRACE, R H, GENI, A E, and HELLIER, M D: Comparative trial of sodium

cromoglycate enemas with prednisolone enemas in the treatmentof ulcerative colitis (Clinical trial), 88

GRAHAME-SMIrFH, D G: What is the cause of the carcinoid flush?(Leadinig article), 1413

GRAINGER, S L. See MAX'I'ON, D G, AINLEY, c c, et al.Granulocytes, l''In-labelled, and al-antitrypsin, faccal excretion of,

in assessment of disease activity in chronic inflammatory boweldiseases, 386

GREGORY, H. See GOODLAD, R A, WIllSON, T J G, et al.GRIGOLO, B. See SCIARRE'I'A, G, FAGIOLI, G, et al.GRIME, J s. See BAX'I'ER, J N, GRIME, J s, et al.

See MACKIE, C R, BAXrER, J N, et al.See PARR, N J, GRIME, J S, etal.

GUAN, R, RAWCLIFFE, P M, PRIDDLE, J D, and JEWEILL, D P: Cellularhypersensitivity to gluten derived peptides in coeliac disease, 426

GUARNER, F, HUGHES, R D, GIMSON, A E S, and WILLIAMS, R: Renalfunction in fulminant hepatic failure: haemodynamics and renalprostaglandins, 1643

GUGLER, R. See BAUFRFEIND, P, CILLUFFO, 'i1, et al.GUILLAN, J. See ROULO(I', D, VALLA, D, et al.GUILLOU, P J. See MONSON, J R T, RAMSDEN, C w, et al.GUMP, D. See BEEKEN, W, NOR1'HWOOD, I, et al.GUPTA, S, BARTER, S, PHILLIPS, G W L, GIBSON, R N, and HODGSON, H J F:Comparison of ultrasonography, computed tomography and`"TC livcr scan in diagnosis of Budd-Chiari syndrome, 242

GUSLANDI, M: Erosive gastritis- does acid matter? (Letter), 1321GUS'rAFSEN, J, BOESBY, S, NIELSEN, F, and GIESE, J: Bradykinin in

carcinoid syndrome, 1417Gut referees, 108Gut. See Gastrointestinal tractGUTHRIE, E. See CREED, F, and GUIHRIE, EGWAVAVA, N. See KIIRE, C F, and (WAVAVA, NGYR, K. See MARBET, U A, S'lALDER, G A, et al.

HADJIS, N S, and BLUMGARI, L H: Role of liver atrophy, hepaticresection and hepatocyte hyperplasia in the development of portalhypertension in biliary disease, 1022

Haem biosynthesis and porphyrin metabolism in Gilbert's syndrome,125

Haemodynamics and renal prostaglandins, relation to renal functionin fulminant hepatic failure, 1643

Haemoperitoneum, spontaneous, from rupture of primary hepaticadenoma in adult man (Case report), 1170

Haemorrhage, gastrointestinal. See Gastrointestinal haemorrhage? variceal, comparison between trials invalidated by variation in

time of entry of subjects?, 653HAGA, Y. See SAKAMOTO, K, HAGA, Y, et al.HAKANSON, R. See BORDI, C, CREUTZFELDT, W, et al.HALEVY, J. See KONIKOFF, F, MOR, C, et al.HALGREEN, H. See szEcsI, P B, HALGREEN, H, et al.HALL, C. See KEIGHLEY, M R B, and HALL, CHALL, C N, KIRKHAM, J S, and NORI'HFIELD, 'I' C: Urinary N-

nitrosoprolinc excretion: a further evaluation of the nitrosaminchypothesis of gastric carcinogencsis in precancerous conditions,216

See also CAYGILl, C P J, HILL, M J, et al.HALL, R I. See INGOLDBY, C J H, MASON, M K, et al.HALL-CRAGGS, M A, and LEES, W R: Fine needle biopsy: cytology,

histology or both? (Leading article), 233HAMALAINEN, E, KORPELA, J i', and ADLERCREUTZ, H: Effect of

oxytetracycline administration on intestinal metabolism of oestro-gens and on plasma sex hormones in healthy men, 439

Hamartoma, neuromuscular and vascular, of small intestine as formof Crohn's disease (Case reports), 1663

HAMASHIMA, Y. See KUDO, H, INADA, M, et al.HANSEN, T. See JORDE, R, BURHOL, P G, et al.HANSEN, I M. See MANNICHE, C, MALCHOW-M0LLER, A, et al.HANY, A. See HEER, M, REPOND, F, et al.

General index

HARDER, F. See MARBET, U A, STALDER, G A, et al.HARDY, K J. See BIGGS, B A, CROWE, S M, et al.HARRE, K. See MERKI, H, WITZEL, L, et al.HARRIS, S R. See PRIOR, A, HARRIS, S R, et al.HARRISON, J, MORRIS, D L, HAYNES, J, HITCHCOCK, A, WOMACK, c, andWHERRY, D C: Electrohydraulic lithotripsy of gall stones - in vitroand animal studies, 267

HARRISON, T J. See ANDERSON, M G, HARRISON, T J, et al.HART, C A. See BATT, R M, HART, C A, et al.HARVEY, R F: Achlorhydria: hypergastrinaemia: carcinoids (Letter),

1319See also BROWN, A M, BRADSHAW, M J, etal.

HAWES, R. See BOWN, S G, HAWES, R, et al.HAWKEY, C J. See WALT, R P, KEMP, R T, et al.HAYNES, J. See HARRISON, J, MORRIS, D L, etal.HEADING, R C. See CHAKRABORTY, T K, BHATIA, D, et al.

See DE CAESTECKER, J S, BLACKWELL, J N, et al.See KING, P M, PRYDE, A, et al.

HEARNS, J. See MCCOLL, K E L, BUCHANAN, N M M, et al.HEATON, K W. See MARCUS, S N, and HEATON, K W

See OETTLE, G J, and HEATON, K WHEER, M, REPOND, F, HANY, A, SULSER, H, KEHL, o, and JAGER, K:Acute ischaemic colitis in a female long distance runner (Casereport), 896

HEINRICH, C. See SCHINDLBECK, N E, HEINRICH, C, et al.HELLEBERG, L. See MANNICHE, C, MALCHOW-M0LLER, A, et al.HELLIER, M D. See GRACE, R H, GENT, A E, et al.HEMINGWAY, A P. See THOMPSON, J N, SALEM, R R, et al.HENDEL, J. See HENDEL, L, HENDEL, J, et al.HENDEL, L, HENDEL, J, and JOERGENSEN, i: Enterocyte function in

progressive systemic sclerosis as estimated by the deconjugationof pteroyltriglutamate to folic acid, 435

HENRIKSEN, J H, RING-LARSEN, H, and CHRISTENSEN, N i: Hepaticintestinal uptake and release of catecholamines in alcoholiccirrhosis: evidence of enhanced hepatic intestinal sympatheticnervous activity, 1637

HENSBY, C N. See BENNETT, A, CIVIER, A, etal.Hepatic encephalopathy, comparative modes of action of lactitoland lactulose in treatment of, 255

failure, fulminant, renal function in, relation to haemody-namics and renal prostaglandins, 1643-

1, , with cerebral oedema, neurological sequelae in 2patients recovered from (Case reports), 93

intestinal uptake and release of catecholamines in alcoholiccirrhosis, evidence of enhanced hepatic intestinal sympatheticnervous activity in, 1637

sarcoma in adults, 25 cases reviewed, 668Hepatitis, alcoholic, acute, cellular injury in, free radical generation

by neutrophils as potential mechanism of, 1157B, active, chronic, lymphoblastoid interferon for (Clinical

trial), 619,chronic, HBe antigen positive, effect of recombinant inter-

leukin 2, 1648,viral, acute, intestinal function during, investigation using

combined sugar oral loads, 1439Hepatocellular adenoma, primary, rupture of, in adult man, spon-

taneous haemoperitoneum from (Case report), 1170carcinoma, primary, lysis of tumour cells by lymphokine-

activated killer cells in, 117Hepatocyte injury in acute alcoholic hepatitis, free radical genera-

tion by neutrophils as potential mechanism of, 1157HERMANOWICZ, A, GIBSON, P R, and JEWELL, D P: Tumour related

inhibition of macrophage chemotaxis in patients with coloncancer, 416

HESSE, B. See J0RGENSEN, F, HESSE, B, etal.HICKSON, F. See HOUGHTON, L A, HICKSON, F, et al.HIGGS, N B. See MORIARTY, KJ, HIGGS, N B,et al.HILL, I D, and ALTMAN, D G: Need for confidence intervals in reporting

clinical trials (Letter), 1549HILL, M J. See CAYGILL, C P J, HILL, M J, et al.

1703

See THOMAS, J M, MISIEWICZ, J J, et al.HILL, P G. See TURNER, J M, LAWRENCE, S, et al.HINCHLIFFE, R F C. See BARDHAN, K D, THOMPSON, M, et al.Hindgut, rabbit, propionate absorption and metabolism in, 1077Histamine H2-receptor. See H2-receptorHITCHCOCK, A. See HARRISON, J, MORRIS, D L, etal.HIV infection, rectal mucosa of men with and without, immuno-

logical study of, 1619HLA-DR expression, natural killer cells and IgE containing cells in

jejunal mucosa of coeliac children, 988HOBSLEY, M. See WHITFIELD, P F, and HOBSLEY, MHODGSON, H J F. See GUPTA, S, BARTER, S, et al.

See THOMPSON, J N, SALEM, R R, etal.HOEK, F J, BERGH, F A J T M VAN DEN, KLEIN ELHORST, J T, MEIJER, J L,

TIMMER, E, and TYTGAT, G N J: Improved specificity of the PABAtest with p-aminosalicylic acid, 468

HOLDEN, S. See EDWARDS, C A, HOLDEN, s, et al.HOLDSWORTH, C D. See RAO, S S C, READ, N W, et al.HOLLANDER, D, and TARNAWSKI, A S: Essential fatty acids and peptic

ulcer disease (Letter), 915HOLLY, J. See O'BRIEN, J D, THOMPSON, D G, et al.HOLMES, G K T. See TURNER, J M, LAWRENCE, s, et al.HOLMFIELD, J H M. See WOMACK, N R, WILLIAMS, N s, et al.HOLST, J J. See JENSEN, S L, HOLST, J J, etal.HOLT, S. See FINCH, P J, RYAN, F P, et al.HOPF, U. See ZEITZ, M, HOPF, U, et al.HOPKER, W W. See LIMBERG, B, HOPKER, w w, etal.HORI, R. See KANG, J Y, WU, A Y T, et al.HORIIKE, N. See ONJI, M, KONDOH, H, et al.HOSKING, S W, ROBINSON, P, and JOHNSON, A G: Effect of Valsalva'smanoeuvre and hyoscinbutylbromide on the pressure gradientacross the wall of oesophageal varices, 1151

HOSODA, S. See SENDA, S, FUJIYAMA, Y, et al.HOST, A. See HUSBY, S, FOGED, N, et al.HOTZ, J. See LAYER, P, HOTZ, j, et al.HOUGHTON, L A, HICKSON, F, and READ, N W: Effect of food

consistency on gastric emptying in man, 1584HOWDEN, C W, and HUNT, R H: Relationship between gastric secretionand infection (Progress report), 96

See also JONES, D B, HOWDEN, C W, etal.H2-receptor and anti-muscarinic receptor blockade, combined, in

healing of refractory duodenal ulcer, 1505antagonist (cimetidine), large single dose of, for duodenal

ulcer, size of dose and timing, clinicopharmacological study, 566antagonists, effect on intragastric acidity, influence of smoking

on, trial of, 549See also Ranitidine

HSIEH, K H, SHU, S, LEE, C S, CHU, C T, YANG, C S, and CHANG, K J: Lysisof primary hepatic tumours by lymphokine activated killercells, 117

HUDSON, M J. See BARR, G D, HUDSON, M J, et al.HUGHES, B R. See MYERS, B, EVANS, D N W, et al.HUGHES, R D. See GUARNER, F, HUGHES, R D, et al.HUI, w M, and LAM, S K: Multiple duodenal ulcer: natural history and

pathophysiology, 1134HULKS, G. See MACKIE, C R, BAXTER, J N, et al.Humoral, cell mediated and antibody dependent cell mediated

cytotoxic responses, alterations during amoebic infection inguinea pigs, 1251

HUMPHREYS, J F H. See NOLAN, N P M, KELLY, CP, et al.HUNT, R H. See HOWDEN, C w, and HUNT, R H

See JONES, D B, HOWDEN, C w, et al.HUSBY, S, FOGED, N, HOST, A, and SVEHAG, S-E: Passage of dietary

antigens into the blood of children with coeliac disease: quantifica-tion and size distribution of absorbed antigens, 1062

Hydatid cysts, albendazole sulphoxide penetration into, 75Hydrogen analysis, adaptation for measurement of stomach tocaecum transit time in rat, 849

breath test, evaluation of, and definition and elimination ofearly hydrogen peak, 721

1704 General index

Hyoscinbutylbromide and Valsalva's manoeuvre, effects onpressure gradient across wall of oesophageal varices, 1151

Hypergastrinaemia and achlorhydria as causal sequence for gastriccarcinoid tumours, reassessment of (Progress report), 488;(Letters), 1189, 1191, 1319

Hypertension, portal, gastric mucosa in (Letter), 1324, in biliary disease, development of, role of liver atrophy,

hepatic resection and hepatocyte hyperplasia in, 1022Hypnotherapy in severe irritable bowel syndrome, 423

IIDA, M. See NISHIDA, T, MIWA, H, etal.IISHI, H. See TATSUTA, M, IISHI, H, et al.Ileostomy and colectomy, patient's reactions to, personal account,

81Ileum, rabbit, organ culture of, as model for investigation ofmechanism of intestinal damage by enteropathogenic Escherichiacoli, 1283-, rat, enterocytes adapting to proximal small bowel resection,

increased activity of digestive enzymes in, 981,transport, effect of serotonin, cisapride inhibition of,

evidence for involvement of 5-HT2 receptors in, 844IMAMURA, S. See MIYACHI, Y, YOSHIOKA, A, et al.Immunoglobulin A subclasses, local alterations in ulcerative colitisand Crohn's disease of colon, 1013

A, and sIgA, colonic bacterial proteases to, in ulcerativecolitis, 186; (Letter), 917

allotypes in Crohn's disease in Netherlands, 610E containing cells, HLA-DR expression and natural killer cells

in jejunal mucosa of coeliac children, 988plasma cell and intraepithelial mast cell response, rectal

spirochaetosis associated with, 2 cases of, 588,local production of, difference between gastritis associated

with dermatitis herpetiformis and simple gastritis, 1589Immunological study of rectal mucosa of men with and without HIV

infection, 1619INADA, M. See KUDO, H, INADA, M, et al."'Indium-labelled granulocytes and al-antitrypsin, faecal excretion

of, in assessment of disease activity in chronic inflammatory boweldiseases, 386

INDRAN, M. See GALLOWAY, D J, JARRErT, F, et al.INGOLDBY, C J H, MASON, M K, and HALL, R t: Endoscopic needle

aspiration cytology: a new method for the diagnosis of uppergastrointestinal cancer, 1142

Interferon, lymphoblastoid, for chronic active hepatitis B (Clinicaltrial), 619

Interleukin 2, recombinant, effect on hepatitis Be antigen positivechronic hepatitis, 1648

International Organisation for the Study of Inflammatory BowelDisease: Report No 1: Observer variation in calculating indices ofseverity and activity in Crohn's disease, 474

Intestinal adenovirus, human, role in pathogenesis of coeliacdisease, evidence for, 995

schistosomiasis, protein losing enteropathy due to (Casereport), 616

sympathetic nervous activity, hepatic, enhanced, evidence of,in hepatic intestinal uptake and release of catecholamines inalcoholic cirrhosis, 1637

Intestine, large, and portal, hepatic and venous blood, human, shortchain fatty acids in, 1221

,rat, and human large intestine, normal and inflamed,mucosal surface pH of, 707

See also Hindgutsmall, adenocarcinoma of, and neurofibromatosis, association

between (Case report), 1173, Crohn's disease of, active, abnormal lactulose/rhamnose

permeability in, improvement by elemental diet, 1073-, ,enterocyte turnover in rat, effect of chronic ethanol

ingestion, 52- , hamartoma of, neuromuscular and vascular, as form of

Crohn's disease (Case reports), 1663

human, permeability, effcct of NSAIDs and prostaglan-dins, statistical assessment (Letters), 777

, involvement in progressive systemic sclerosis detectedby increased unconjugated serum bile acids, 446

, lactase activity and active galactose absorption in rat,effect of chronic ethanol ingestion, 56,-, ,motor responses to intraluminal distension in normalvolunteers and in patient with visceral neuropathy, 714

mouse, intraepithelial lymphocytes from, inability toinduce systemic graft-versus-host reaction duc to failure tomigrate in vivo, 1267

mucosa of, increased phospholipase A, and decreasedlysophospholipase activity after ischaemia and revascularisationin, 1445

, proximal, resection of, rat ileal enterocytes adapting to,increased activity of digestive enzymes in, 981- , ,resection of, neurotensin-like immunoreactivity in ratafter, 1107

resistances in, and gastroduodenal brake, 950response to 'elemental' and 'complete' liquid feeds in

rat, effect of dietary bulk, 688-, -, transit, correlation with 75SeHCAT test results in detec-

tion of bile acid malabsorption in functional diarrhoea, 970Intestines, carcinogenesis, experimental, and enteroglucagon in rat,33

,damage by enteropathogenic Escherichia coli, mechanism of,organ culture of rabbit ileum as model for investigation of, 1283

,dietary macromolecular absorption, possible role in disease(Leading article), 1057

,epithelium, response to refeeding in rat, effects of elementaldiet, inert bulk, and dietary fibre and relationship to plasmagastrin, enteroglucagon, and PYY concentrations, 171

, function during acute viral hepatitis, investigation using com-bined sugar oral loads, 1439

,human, distribution of 10000 molecular weight calcium bind-ing protein along small and large intestine, 878

,inflammatory disease, chronic, abnormal arachidonic acidmetabolism with enhanced release of leucotriene B4 fromactivated neutrophils in, 181

,disease activity in, assessment from faecalexcretion of a1-antitrypsin and "'In-labelled granulocytes, 386

colonic epithelial dysplasia in, colonoscopy screen-ing for, 1489

,in childhood, stoma surgery for, psychosocialsequelae of, 1257

osteoporosis in, 410,psychiatric illness in, 1600related to reactive arthritis, histopathology of, 394

irritable bowel syndrome, bran efficacious in? (Clinical trial),221

colonic motility in, reduction by intravenousnicardipine, 1609_,- , ispaghula husk in, optimum dosage and

correlation of symptom relief with whole gut transit time and stoolweight, 150

ispaghula in, 1510- ,painless diarrhoea of, colonic myoclectrical

activity in, 1613psychological factors in (Progress report),

1307-,relation to life events and psychiatric illness,

160,severe, hypnotherapy in, 423,symptoms related to objective measurements

of large bowel function?, 146; (Letter), 1321bowel-type symptoms in spontaneous and induced con-

stipation, 156, lamina propria, and peripheral blood, lymphocyte activation

in Crohn's disease defined by expression of early activationantigens in, 745

General index

,motor disturbances in rat after laparotomy, involvement ofalpha-I and alpha-2 adrenoceptors in, 955

neonatal rat, development of phospholipase A, and lysophos-phatidylcholine metabolising enzyme activities in, 822

,oestrogen metabolism, and plasma sex hormones in hcalthymen, effect of oxytetracycline, 439-, permeability studies, molecular radii of probes used in

(Letter), 110, pseudo-obstruction, idiopathic, chronic, clinical and intestinal

manometric findings in, 5-, transport and morphology, effects of auranofin and

myochrysine, 829, trophic effect of intravenous (but not intragastric)

urogastrone-EGF in parenterally fed rats, 573Intraabdominal pressure rises, preservation of faecal continence

during, role for flap valve in?, 1242Intraepithelial mast cell and IgE plasma cell response, rectal

spirochaetosis associated with, 2 cases of, 588Intragastric acidity, effect of histamine H.-receptor antagonists,

influence of smoking on, trial of, 549, suppression of, in duodenal ulcer, meta-analysis defining

optimal dosing with antisecretory drugs for, 1120bile acid concentrations unrelated to flatulent dyspepsia in

patients with and without gallbladder disease and post-cholecystectomy, 131pH and gastric acid output, overnight, effect of bedtimc

ranitidine, dose/response study and comparison with cimetidine,294

effect on antral gastrin and somatostatin release in

anaesthetised, atropinised duodenal ulcer patients and controls,206

Intraluminal pH monitoring, technical aspects, current status andrecommendations (Progress report), 1177

ISBERG, P-E. See JOHNSSON, F, JOELSSON, B, etal.Ischaemia and revascularisation, increased phospholipase A2 and

decreased lysophospholipase activity in small intestinal mucosa

after, 1445ISLAM, M. See BUILER, T, DAHMS, B, et al.ISLAM, M R: Single dose tetracycline in cholera (Clinical trial), 1029Ispaghula husk in irritable bowel syndrome, optimum dosage and

correlation of symptom relief with whole gut transit time and stoolweight, 150

in irritable bowel syndrome, 1510IZZO, C M. See PARRILLI, G, CUOMO, R, et al.

JAGELMAN, D G. See SARRE, R G, FROST, A G, et al.JAGER, K. See HEER, M, REPOND, F, et al.JARRE11, F. See GALLOWAY, D J, JARRE-I1l, F, et al.JASS, J R. See MELVILLE, D M, NORrHOVER, J M A, et al.-. See SHEPHERD, N A, and JASS, J R

JEFFRIES, D J. See WEBER, J N, THOM, s, et al.Jejunum, mucosa of, in coeliac children, HLA-DR expression,

natural killer cells and IgE containing cells in, 988rat, effects of olsalazine, 346water and electrolyte absorption from 2 enteral feeds, import-

ance of sodium content in, 681JENKINS, D, RICHARDS, J E, REES, Y, and WICKS, A C B: Multiple listerial

liver abscesses (Case report), 1661JENKINS, J. See LASK, B, JENKINS, J, et al.JENKINS, S A. See BAXTER, J N, GRIME, J s, et al.JENKINS, W J. See MAZZANTI, R, DEBNAM, E S, et al.-. See MAZZANTI, R, and JENKINS, W J

JENSEN, H-E. See JENSEN, S L, HOLST, J J, etal.JENSEN, S L, HOLST, J J, CHRISTIANSEN, L. A, SHOKOUH-AMIRI, M H,

LORENTSEN, M, BECK, H, and JENSEN, H-E: Effect of intragastric pHon antral gastrin and somatostatin release in anaesthetised,atropinised duodenal ulcer patients and controls, 206

JESS, P. See MANNICHE, C, MALCHOW-MOLLER, A, et al.JEWELL, D P. See BARR, G D, HUDSON, M J, et al.

See GEBBERS, J-O, FERGUSON, D J P, et al.

1705

See GUAN, R, RAWCLIFFE, P M, et al.See HERMANOWICZ, A, GIBSON, P R, et al.

- See MOHSEN, A Q M, MUILVEY, D, et al.JOELSSON, B. See JOHNSSON, F, JOELSSON B, et al.JOERGENSEN, 1. See HENDEL, L, HENDEL, J, et al.JOHANSSON, C. See EINARSSON, K, ANGELIN, B, etal.JOHNSON, A G. See HOSKIN(, S W, ROBINSON, P, et al.JOHNSON, I. See TURNER, J M, LAWRENCE, S, etal.JOHNSON, P. See FORBES, A, PORTMANN, B, etal.JOHNSSON, F, JOELSSON, B. and ISBERG, P-E: Ambulatory 24 hour

intraoesophageal p11-monitoring in the diagnosis of gastro-oesophageal reflux disease, 1145

JONES, B J M. See SPILt.ER, R C, JONES, B J M, et al.JONES, D B, HOWDEN, C W, BURGEI, D W, KERR, G D, and HUNT, R H:

Acid suppression in duodenal ulcer: a meta-analysis to defineoptimal dosing with antisecretory drugs, 1120

JONES, P F: Anastomotic recurrence of colorectal cancer (Letter),1691

JONES, T J, and MARSHALL, T 1: Neurofibromatosis and small boweladenocarcinoma: an unrecognised association (Case report), 1173

JORDE, R, BURHOL, P G, and HANSFN, T: Ranitidine 150 mg at night inthe prevention of gastric ulcer relapse, 460

JORGENSEN, F, HESSE, B, and ELSBORG, L: Scintigraphic assessment ofoesophageal motility (Letter), 363

JUDD, D. See COMPSTON, J E, JUDD, D, et al.

KAGNOFF, M F, PATERSON, Y J, KUMAR, P J, KASARDA, D D, CARBONE, F R,

UNSWORTH, D J, and AUSIIN, R K: Evidence for the role of a humanintestinal adenovirus in the pathogenesis of coeliac disease, 995

KALVARIA, 1, BORNMAN, P C, GIRDWOOD, A H, and MARKS, I N:

Periampullary cyst: a surgically remediable cause of pancreatitis(Case report), 358

KANG, J Y, WU, A Y 'I, CHIA, J L S, WEE, A, SUIHERLAND, I H, and HORI, R:

Clinical and ultrastructural studies in duodenal pseudomelanosis(Case reports), 1673

Kaposi's sarcoma, AIDS-related, presenting as ulcerative colitis andcomplicated by toxic megacolon, 1302

KARAUS, M, SARNA, S K, AMMON, H v, and WIENBECK, M: Effects of orallaxatives on colonic motor complexes in dogs, 1112

KARLSTADT, R G, FRANK, W 0, ANTELL, L A, SHAPOWAL, S W, andPALMER, R H: Cimetidine and ranitidine on basal and ACTH-stimulated steroidogenesis (Letter), 1688

KARRAN, S. See MCLAREN, M, BRAYE, S, et al.KASARDA, D D. See KAGNOFF, M F, PA'I'ERSON, Y J, et al.KEHL, O. See HEER, M, REPOND, F, et al.KEIGHLEY, M R B, and HALL, C: Anastomotic recurrence of colorectalcancer- a biological phenomenon or an avoidable calamity?(Leading article), 786

KELLOW, J E, GILL, R C, and WINGATE, D L: Modulation of humanupper gastrointestinal motility by rectal distension, 864

See also GILL, R C, KELLOW, J E, et al.KELLY, C P. See NOLAN, N P M, KELLY, C P, et al.KELLY, M P: Managing radical surgery: notes from the patient's

viewpoint, 81KELLY, P. See GEBBERS, J-O, FERGUSON, D J P, et al.KEMENY, N. See ALLEN-MERSH, T G, KEMENY, N, et al.KEMP, R T. See WALT, R P, KEMP, R T, et al.KENDALL, G P N, THOMPSON, D G, and DAY, S J: Motor responses of the

small intestine to intraluminal distension in normal volunteers anda patient with visceral neuropathy, 714

and GARVIE, N: Motor responses of the oesophagusto intraluminal distension in normal subjects and patients withoesophageal clearance disorders, 272

KENYON, C J, FRASER, R, CONNELL, J M C, and LEVER, A F: Cimetidineand ranitidine on basal and ACTH-stimulated steroidogenesis(Letter), 1690

KERR, G D. See JONES, D B, HOWDEN, c w, etal.KEI'r, K, and BRANDIZAEG, P: Local IgA subclass alterations in

ulcerative colitis and Crohn's disease of the colon, 1013

1706

KHUFFASH, F A, BARAKAT, M H, SHALTOUT, A A, FARWANA, S S, ADNANI,M S, and TUNGEKAR, M F: Coeliac disease among children inKuwait: difficulties in diagnosis and management, 1595

KIIRE, C F, and GWAVAVA, N: Protein losing enteropathy: an unusualpresentation of intestinal schistosomiasis (Case report), 616

Killer cells. See Lymphokine-activated killer cells; Natural killercells

KING, C. See BARDHAN, K D, THOMPSON, M, et al.KING-, P M, PRYDE, A, and HEADING, R C: Transpyloric fluid movementand antroduodenal motility in patients with gastro-oesophagealreflux, 545

KIRKEGAARD, P. See OLSEN, P S, PEDERSEN, J H, et al.KIRKHAM, J S. See CAYGILL, C P J, HILL, M J, etal.

See HALL, C N, KIRKHAM, i S, et al.KJAER, T. See SZECSI, P B, HALGREEN, H, et al.KLEIN ELHORST, J T. See HOEK, F J, BERGH, F A J T M VAN DEN, et al.KLEMOLA, T. See ARATO, A, SAVILAHTI, E, et al.KOCH, W. See FISCHBACH, W, BECKER, W, etal.KOCHHAR, R, and MEHTA, S K: Colorectal carcinoma in ulcerative

colitis (Letter), 917See also BHASIN, D K, KOCHHAR, R, etal.

KOHLER, W. See BAUERFEIND, P, CILLUFFO, T, et al.KOMMERELL, B. See LIMBERG, B, HOPKER, W W, etal.KOMOROWSKI, R A. See AMMON, H V, FOWLE, S A, etal.KONDOH, H. See ONJI, M, KONDOH, H, et al.KONIKOFF, F, MOR, C, STERN, S, SHAKLAI, M, HALEVY, J, and THEODOR,

E: Cholestasis and liver failure with lambda-AL amyloidosis (Casereport), 903

KONTUREK, J W. See KONTUREK, S J, KWIECIEN~, N, et al.KONTUREK, S J, BILSKI, J, KWIECIEN~N, OBTULOWICZ, W, KOPP, B, and

OLEKSY, i: De-Nol stimulates gastric and duodenal alkalinesecretion through prostaglandin dependent mechanism, 1557

, KWIECIEN, N,OBTUlOWICZ, W, THOR, P, KONTUREK, J W, POPIELA,T, and OLEKSY, J: Vagal cholinergic control of gastric alkalinesecretion in normal subjects and duodenal ulcer patients, 739;(Letter, by Konturek), 1687

, POPIELA, T, SfOWIACZEK, M, and BIELAN~SKI, w: Gastric acid andpancreatic polypeptide responses to modified sham feeding:effects of truncal and parietal cell vagotomy, 280

, RADECKI, T, PIASTUCKI, 1, BRZOZOWSKI, T, and DROZDOWICZ, D:Gastrocytoprotection by colloidal bismuth subcitrate (De-Nol)and sucralfate: role of endogenous prostaglandins, 201

KOPP, B. See KONTUREK, SJ, BILSKI,J, et al.KORPELA, J T. See HAMALAINEN, E, KORPELA, J T, et al.KRASNER, N, BARR, H, SKIDMORE, c, and MORRIS, A 1: Palliative laser

therapy for malignant dysphagia, 792KRAWIEC,J. See ODES, HS, FRASER, D, et al.KRISTENSEN, E. See LARSEN, B, TARP, U, etal.KRUSE-ANDERSEN, S, WALLIN, L, and MADSEN, T: Relationshipbetween spontaneous non-propagating pressure activity in theoesophagus and acid gastro-oesophageal reflux in pathologicaland non-pathological refluxers, 1478

KUDO, H, INADA, M, OHSHIO, G, WAKATSUKI, Y, OGAWA, K, HAMASHIMA,

Y, and MIYAKE, T: Immunohistochemical localisation of vitaminB12 R-binder in the human digestive tract, 339

KUMAR, A, KUMAR, N, VIJ, J C, SARIN, S K, and ANAND, B S: Optimumdosage of ispaghula husk in patients with irritable bowel syn-

drome: correlation of symptom relief with whole gut transit timeand stool weight, 150

KUMAR, N. See KUMAR, A, KUMAR, N, et al.KUMAR,P J. See KAGNOFF, M F, PATERSON, YJ, et al.KUMON, I. See ONJI, M, KONDOH, H, et al.KWIECIEN4, N. See KONTUREK, SJ, BILSKI,J, etal.

See KONTUREK, SJ, KWIECIEN~,N, et al.

Lactase activity and active galactose absorption in rat smallintestine, effect of chronic ethanol ingestion, 56

Lactitol and lactulose, comparative modes of action in treatment ofhepatic encephalopathy, 255

Lactulose, long term ingestion, effect on secondary bile salt meta-

General index

bolism and potential protective effect in colonic carcinogenesis,675

Lactulose/rhamnose permeability, abnormal, in active Crohn'sdisease of small bowel, improvement by elemental diet, 1073

LAFERLA, G. See MCCOLL, K E L, BUCHANAN, N M M, et al.LAM, S K. See HUI, w M, and LAM, S KLAMONT, G, EVANS, D, and REYNOLDS, J: Symptoms of IBS and

objective measurements of large bowel function (Letter), 1321LANGE, G G DE. See BIEMONID, 1, LANGE, G G DE, et al.Laparotomy, intestinal motor disturbances in rat after, involvement

of alpha-I and alpha-2 adrenoceptors in, 955LARSEN, B, TARP, U, and KRISTENSEN, E: Familial giant hypertrophic

gastritis (Menetrier's disease) (Case report), 1517Laser palliation, Nd YAG, endoscopic, for advanced malignant

dysphagia, 799therapy, Nd YAG, palliative, for malignant dysphagia, 792

LASK, B, JENKINS, J, NABARRO, L, and BOOTH, 1: Psychosocial sequelacof stoma surgery for inflammatory bowel disease in childhood,1257

LAU, W Y, FAN, S T, WONG, S H, WONG, K P, POON, G P, CHU, K W, YIP,w c, and WONG, K K: Preoperative and intraoperative localisationof gastrointestinal bleeding of obscure origin, 869

LAURITSEN, K, LAURSEN, L S, BUKHAVE, K, and RASK-MADSEN, J: In vivoeffects of orally administered prednisolone on prostaglandin andleucotriene production in ulcerative colitis, 1095

LAURSEN, L S. See LAURITSEN, K, LAURSEN, L S, et al.LAWES, I N C. See ASALA, S A, BOWER, A J, et al.LAWLEY, TJ. See ZEITZ, M, HOPF, U, etal.LAWRENCE, S. See TURNER, J M, LAWRENCE, S, etal.Laxatives, oral, effects on colonic motor complexes in dogs, 1112LAYER, P, HOTZ, J, CHERIAN, L, and GOEBELL, H: In vitro stimulation of

pancreatic enzyme discharge by calcium, 1215LAZZARONI, M. See BIANCHI PORRO, G, PARENTE, F, etal.LEARDI, S. See SIMI, M, LEARDI, S, et al.LECARPENTIER, J. See RILEY, S A, LECARPENTIER, J, et al.LEE, C S. See HSIEH, K H, SHU, S, et al.LEE, M G. See MYERS, B, EVANS, D N W, et al.LEE, Y C. See SPILLER, R C, LEE, Y c,etal.LEES, W R. See HALL-CRAGGS, M A, and LEES, W RLEISNER, B. See STELLAARD, F, SAUERBRUCH, T, et al.LEMANN, M, MESSING, B, D'AGAY, F, and MODIGLIANI, R: Crohn's

disease with respiratory tract involvement (Case reports), 1669LENNARD-JONES, J E. See MELVILLE, D M, NORTHOVER, J M A, et al.LENTON, W. See GOODLAD, R A, LENTON, W, et al.

See GOODLAD, R A, WILSON, TJ G, et al.Leucotriene and prostaglandin production in ulcerative colitis, in

vivo effects of oral prednisolone, 1095B4, enhanced release from activated neutrophils in chronic

inflammatory bowel disease, 181LEVER, A F. See KENYON, CJ, FRASER, R, et al.LEVI, J A. See BJARNASON, 1, WILLIAMS, P, et al.LEWIN, M R. See GELISTER, J S K, LEWIN, M R, et al.Life events and psychiatric illness, relation to irritable bowelsyndrome, 160

LIMBERG, B, HOPKER,W W, and KOMMERELL, B: Histologic differentialdiagnosis of focal liver lesions by ultrasonically guided fine needlebiopsy, 237

LINDMARK, D. See OTAMIRI, T, FRANZEN, L, et al.LINDPAINTNER, K. See BUTLER, T, DAHMS, B, et al.LINDSAY, D C. See AL MARDINI, H, LINDSAY, DC, et al.LINDSTEDT, G. See LUNDELL, L, LINDSTEDT, G, et al.LING, K L E. See MCNEIL, N 1, LING, K L E, et al.Lipids, biliary, metabolism in chronic pancreatitis, influence of

steatorrhoea, 1495Lipopolysaccharides from E coli, complement fixing antibodies

against, absence in subgroup of patients with Crohn's disease,1460

Liquid test meal, lactulose labelled, delayed mouth-to-caecumtransit in patients with steatorrhoea caused by partially treatedcoeliac disease, 1275

General index

Listerial liver abscesses, multiple (Case report), 1661Lithotripsy, electrohydraulic, of gall stones, in vitro and animal

studies, 267Liver abscesses, listerial, multiple (Case report), 1661

cell. See Hepatocellular; Hepatocytecirrhosis and non-cirrhotic portal fibrosis, measurement and

correlation of wedged hepatic, intrahepatic, intrasplenic andintravariceal pressures in, 260

disease, bacterial infection problems in (Progress report), 623failure and cholestasis with lambda-AL amyloidosis (Case

report), 903lesions, focal, histologic differential diagnosis by ultrasonically

guided fine needle biopsy, 237metastases in rat model, degradable starch microspheres for,

temporary blood flow stasis with, 1201of patient with prolonged fever, isolation of Chlamydia

trachomatis from (Case report), 1514. See also Hepatic

LLOYD, R S. See ROBERTSON, D A F, Al.DERSLEY, M A, etal.LOEFFLER, R F. See AMMON, H V, FOWLE, S A, etal.LOFBERG, R, TRIBUKAIT, B, OST, A, BROMSTROM, o, and REICHARD, H:Flow cytometric DNA analysis in longstanding ulcerative colitis: amethod of prediction of dysplasia and carcinoma development?,1100

LOGAN, R F A: The need for confidence intervals in reporting clinicaltrials (Letter), 916

LONDONG, V. See LONDONG, W, LONDONG, v, etal.LONDONG, W, LONDONG, V, MEIERL, A, and VODERHOLZER, U:Telenzepine is at least 25 times more potent than pirenzepine - adose response and comparative secretory study in man, 888

LONG, A. See AFDHAL, N H, LONG, A, et al.LORENTSEN, M. See JENSEN, S L, HOLST, J J, et al.LOUD, F B. See OLSEN, J A, LOUD, F B, etal.LOVE, A H G. See WATSON, R G P, and LOVE, A HGLOWE, J S. See FOSTER, P N, STEWART, M, et al.LOWNDES, J. See LUCEY, M R, CLARK, M L, etal.LUCAS, C R. See BIGGS, B A, CROWE, S M, etal.LUCAS, M L. See MCLAUCHLAN, G, RAWLINGS, J M, etal.LUCEY, M R: The need for confidence intervals in reporting clinical

trials (Letter), 916,CLARK, M L, LOWNDES, J, and DAWSON, A M: Is bran efficacious

in irritable bowel syndrome?: a double blind placebo controlledcrossover study (Clinical trial), 221

LUDERSCHMIDT, C. See STELLAARD, F, SAUERBRUCH, T, etal.LUNDELL, L. LINDSTEDT, G, and OLBE, L: Origin of gastrin liberated by

gastrin releasing peptide in man, 1128LUNDIN, C. See BORCH, K, RENVALL, H, etal.Lymphoblastoid interferon for chronic active hepittitis B (Clinical

trial), 619Lymphocytes, intraepithelial, from mouse small intestine, inability

to induce systemic graft-versus-host reaction due to failure tomigrate in vivo, 1267

of peripheral blood and intestinal lamina propria, activation inCrohn's disease defined by expression of early activation antigens,745

Lymphokine-activated killer cells in gastrointestinal cancer, 1420in immunotherapy for cancer (Leading article), 113, lysis of primary hepatocellular carcinoma cells by,

117Lysophosphatidylcholine metabolising enzyme and phospholipaseA2 activities, development in neonatal rat intestine, 822

Lysophospholipase activity, decreased, and increased phospho-lipase A2 activity in small intestinal mucosa after ischaemia andrevascularisation, 1445

MCCALLUM, R W. See MITTAL, R K, ROCHESTER, D F, et al.MCCARTHY, C. See BARDHAN, K D, THOMPSON, M, et al.MCCARTHY, C F. See BREEN, E G, FARREN, c, et al.MCCLOY, R F. See MCLAUCHLAN, G, RAWLINGS, J M, et al.MCCOLL, K E L, BUCHANAN, N M M, LAFERLA, G, HEARNS, J, BUCHANAN,

1707

K, and CREAN, G P: Effects of nifedipine on gastric acid secretionand gastrin release in man, 455-, THOMPSON, G G, EL OMAR, E, MOORE, M R, and GOLDBERG, A:

Porphyrin metabolism and haem biosynthesis in Gilbert's syn-drome, 125; (Letter, by McColl), 1549

See also MCLAUCHLAN, G, RAWLINGS, J M, etal.MCCONNELL, R B. See CRAMPTON, J R, TOBIN, M v, etal.MCCULLAGH, K G. See GOODLAD, R A, WILSON, TJ G, etal.MACFARLANE, G T. See CUMMINGS, J H, POMARE, E W, eta!.MCGANNON, E. See SARRE, R G, FROST, AG, etal.MCGLONE, F. See SANDLE, G I, and MCGLONE, FMCHUGH, S M, and DIAMANT, N E: Anal canal pressure profile: a

reappraisal as determined by rapid pullthrough technique, 1234MCINERNEY, P D, VAN DESSEL, M G, and BERSTOCK, D A: Spontaneoushaemoperitoneum from rupture of a primary hepatic adenoma inan adult man (Case report), 1170

MCINTOSH, J H. See NASIRY, R W, MCINTOSH, J H, et al.MCKELVEY, S T D. See MOOREHEAD, R J, CAMPBELL, G R, etal.MACKENZIE, S. See BACA, M E, MOWAT, A MCI, etal.MACKIE, C R, BAXTER, J N, GRIME, J S, HULKS, G, and CUSCHIERI, A: Gall

bladder cmptying in normal subjects - a data base for clinicalcholescintigraphy, 137

See also PARR, N J, GRIME, J s, etal.MCKINLAY, A W. See TAIT, G W, and MCKINLAY, A WMCLAREN, M, BRAYE, S, FLEMING, J, KARRAN, s, and TAYLOR, 1:

Changes in blood flow, portal pressure and shunting during thedevelopment of cirrhosis in response to beta-blockade, 663

MCLAUCHLAN, G, RAWLINGS, J M, LUCAS, M L, MCCLOY, R F, CREAN, G P,and MCCOLL, K E L: Electrodes for 24 hour pH monitoring - acomparative study, 935

MCLEAN, L. See BATT, R M, HART, CA, etal.MCMILLAN, A. See BISHOP, P E, MCMILLAN, A, etal.MCNEIL, D. See TALLEY, N J, MCNEIL, D, etal.MCNEIL, N I, LING, K L E, and WAGER, J: Mucosal surface pH of the

large intestine of the rat and of normal and inflamed large intestinein man, 707

Macromolecules, dietary, intestinal absorption, possible role indisease (Leading article), 1057

Macrophage chemotaxis in colon cancer, tumour related inhibitionof, 416

MACSWEEN, R N M, and WILLIAMS, G T: Future requirements forcolonoscopy in Britain (Letter), 1322

MADSEN, T. See KRUSE-ANDERSEN, S, WALLIN, L, etal.MAHIDA, Y R. See PATIL, D H, WESTABY, D, et al.MAHMOUD, M. See GELISTER, J S K, LEWIN, M R, etal.MAIO, G. See PARRILLI, G, CUOMO, R, etal.MAJUMDAR, A P N. See DUBICK, M A, CONTEAS, C N, etal.Malabsorption, fat, diagnosis of, '4C-triolein absorption test in, 694MALAGELADA, J-R. See STANGHELLINI, V, CAMILLERI, M, et al.MALAGUTI, P. See SCIARRETTA, G, FAGIOLI, G, et al.MALCHOW-MOLLER, A. See MANNICHE, C, MALCHOW-M0LLER, A, et al.MALIK, A K. See VINAYAK, V K, SAXENA, A, et al.MANDAL, B K. See RILEY, S A, LECARPENTIER, J, et al.MANI, v. See RILEY, S A, LECARPENTIER, J, et al.MANNICHE, C, MALCHOW-M0LLER, A, ANDERSEN, J R, PEDERSEN C,HANSEN, T M, JESS, P, HELLEBERG, L, RASMUSSEN, S N, TAGE-JENSEN,u, and NIELSEN, S E: Randomised study of the influence of non-steroidal anti-inflammatory drugs on the treatment of peptic ulcerin patients with rheumatic disease (Clinical trial), 226

MANNING, A P, BULGIM, O R, DIXON, M F, and AXON, A T R: Screening bycolonoscopy for colonic epithelial dysplasia in inflammatorybowel disease, 1489

MARBET, U A, STALDER, G A, FAUST, H, HARDER, F, and GYR, K:Endoscopic sphincterotomy and surgical approaches in the treat-ment of the 'sump syndrome', 142

MARCUS, S N, and HEATON, K W: Irritable bowel-type symptoms inspontaneous and induced constipation, 156

MARKS, I N. See KALVARIA, 1, BORNMAN, P c, et al.MARPLES, M. See MUGHAL, M M, MARPLES, M, et al.MARQUET, J. See BELAICHE, J, ZIrTOUN, j, et al.

1708 General index

MARSHALL, I L. See JONES, T J, and MARSHALL, T L

MARTENSSON, H. See THESLEFF, P, BENONI, C, et al.MARTIN, L E. See THOMAS, J M, MISIEWICZ, J j, et al.MASON, C. See GEBBERS, J-0, FERGUSON, D J P, et al.MASON, M K. See INGOLDBY, C J H, MASON, M K, et al.MASON, R C. See ROWE, P H, TAYLOR, P R, et al.MAS'I'ROPAOLO, G, and REES, W D w: Evaluation of the hydrogen

breath test in man: definition and elimination of the earlyhydrogen peak, 721

MAFIHrEWS, J L. See SAVAGE, A P, MA I-IHEWS, J L, et al.MAI-FHEWSON, K. See BOWN, S G, HAWES, R, et al.MAXTON, D G, AINLEY, C C, GRAINGER, S L, MORRIS, R W, and 'I'HOMPSON,

R P H: Teeth and benign oesophageal stricture, 61,CYNK, E U, and THOMPSON, R P H: Small intestinal response to

,elemental' and 'complete' liquid feeds in the rat: effect of dietarybulk, 688-, and IHOMPSON, R P H: Teeth and benign oesophageal stricture

(Letter), 913MAZZAN'I'l, R, DEBNAM, E s, and JENKINS, W J: Effect of chronic

ethanol intake on lactase activity and active galactose absorptionin rat small intestine, 56

,and JENKINS, W J: Effect of chronic ethanol ingestion onenterocyte turnover in rat small intestine, 52

Megacolon, toxic, AIDS-related Kaposi's sarcoma presenting asulcerative colitis and complicated by (Case report), 1302

MEHTA, S K. See BHASIN, D K, KOCHHAR, R, et al.See KOCHHAR, R, and MEHIA, S K

MEIERI , A. See LONDONG, W, LONDONG, V, et al.MEIJER, J L. See HOEK, F J, BERGH, F A J 'I' M VAN DEN, et al.MEISTER, J-J. See GERTSCH, P, and MEISTER, J-J

MELHUISH, P B. See BENNETri, A, CIVIER, A, et al.MEL'I'ON, L J, [II. See STONNINGTON, C M, PHILLIPS, S F, et al.MELVILLE, D M, NORTHOVER, J M A, JASS, J R, SHEPHERD, N A, and

LENNARD-JONES, J E: DNA aneuploidy in ulcerative colitis (Letter),643

Menetrier's disease (familial giant hypertrophic gastritis) (Casereport), 1517

MFNZIES, 1. See SANDERSON, I R, BOUL'I'ON, P, et al.Meptazinol, enhanced oral bioavailability in cirrhosis, 248MERKI, ti, Wi'I'ZEL, L, HARRE, K, SCHEURLE, E, NEUMANN, J, and

ROHMEL, J: Single dose treatment with H2 receptor antagonists: isbedtime administration too late?, 451

Mesalazine substitution, effect on sulphasalazine induced seminalabnormalities in ulcerative colitis, 1008

Mesenteric blood flow, effect of exercise, 583MESSIN(G, B. See LEMANN, M, MESSING, B, et al.Microbial. See BacterialMIELANIS, H. See CUVELIER, C, BARBAIIS, C, et al.MIKULECKY, M: Porphyrin metabolism in Gilbert's, Dubin-Johnson,

and Rotor's syndromes (Letter), 1548MILLER, P MCC. See FORD, M J, MILLER, P MCC, et al.MILLS, J (. See DEAKIN, M, GLENNY, H P, et al.MISIEWICZ, J J. See THOMAS, J M, MISIEWICZ, J J, et al.MITTAI, R K, ROCHESTER, D F, and MCCALLUM, R W: Effect of the

diaphragmatic contraction on lower oesophageal sphincterpressure in man, 1564

MIWA, H. See NISHIDA, 1, MIWA, H, et al.MIYACHI, Y: Effect of sulphasalazine and its metabolites on the

generation of reactive oxygen species (Letter), 913, YOSHIOKA, A, IMAMURA, s, and NIWA, Y: Effect of sulphasalazine

and its metabolites on the generation of reactive oxygen species,190

MIYAKE, T. See KUDO, H, INADA, M, et al.MODIGLIANI, R. See LEMANN, M, MESSING, B, et al.MOHSEN, A Q M, MULVEY, D, PRIDDLE, J D, PARSONS, D s, and JEWELL,D P: Effects of olsalazine in the jejunum of the rat, 346

MOLLER, B. See ZEITZ, M, HOPF, U, et al.MONSON, J R T, RAMSDEN, C W, GILES, G R, BRENNAN, r G, and GUILLOU,

P J: Lymphokine activated killer cells in patients with gastro-intestinal cancer, 1420

MOORE, M R. See MCCOLIL, K1,E I'HOMPSON, G G, et al.MOOREHEAD, R J, CAMPBELL, G R, DONALDSON, J [, and M(KEIVEY,

S 'I' D: Relationship between duodenal bile acids and colorectalneoplasia. 1454

MOR, C. See KONIKOFF, F, MOR, C, et al.MORELLI, A. See NARDUCCI, F, BASSOrri, G, et al.MORIARIY, K J, HIGGS, N B, WOODFORD, M, WARHURS'I', G, and

IURNBERG, 1. A: Inhibition of the effect of serotonin on rat ilealtransport by cisapride: evidence in favour of the involvement of5-HT2 receptors, 844

MORRIS, A 1. See KRASNER, N, BARR, H, et al.MORRIS, D L, CHINNERY, J B. (GEOR(GIOU, (6, STAMATAKIS, 6, and

00LEMATIS, B: Penetration of alhendazole sulphoxide into hydatidcysts, 75

See also HARRISON, J, MORRIS, D L, et al.MORRIS, R W. See MAXTON, D 6, AINLEY, C C, et al.MORRISON, J F B. See WOMACK, N R, WILLIAMS, N s, et al.M6SSNER, J. See FISCHBACH, W, BECKER, w, et al.Motor complex, migrating, and gastro-oesophageal reflux, 929

responses of small intestine to intraluminal distension innormal volunteers and in patient with visceral neuropathy, 714

Mouth-to-caecum transit, delayed, of lactulose labelled liquid testmeal in patients with steatorrhoea caused by partially treatedcoeliac disease, 1275

time, effect of peptide YY, 166MOWA-I', A MCI. See BACA, M E, MOWAT, A MCI, et al.Mucosa(l). See unider Colon; Gastric: Intestine, small; Jejunum;Rectum

Mucosal surface pH of rat large intestine and human normal andinflamed large intestine, 707

Mucus bicarbonate barrier, functional role ('shield' or 'sieve')(Leading article), 1553

gastric, glycoprotein in, molecular weight of, as pre-determinant of degree of aspirin induced chronic gastriculceration in rat, 287

MUGHAL, M M, MARPLES, M, and BANCEWICZ, J: Scintigraphic assess-ment of oesophageal motility (Letter), 363

MULLER-LISSNER, S A, and BAVARIAN CONSTIPATION S'l'UDY GROUP:Treatment of chronic constipation with cisapride and placebo(Clinical trial), 1033

See also SCHINDLBECK, N E, HEINRICH, c, et a!.MULVEY, D. See MOHSEN, A Q M, MULVEY, D, et al.MUNS'I'ER, D J. See BAGSHAW, P F, MUNSTER, D J, et al.MURRAY, i. See BIRNIE, G,6IHOMPSON, G G, et al.MURRAY-LYON, I M. See ANDERSON, M G, HARRISON, 'I J, et al.MUTCH, F: Fine needle biopsy: effect of needle size (Letter), 912MYERS, B, EVANS, D N W, RHODES, J, EVANS, B K, HUGHES, B R, LEE, M G,

RICHENS, A, and RICHARDS, D: Metabolism and urinary excretion of5-amino salicylic acid in healthy volunteers when given intra-venously or released for absorption at different sites in thegastrointestinal tract, 196

Myochrysine and auranofin, effects on intestinal transport andmorphology in rat, 829

Myoelectrical activity, colonic, in painless diarrhoea of irritablebowel syndrome, 1613

NABARRO, L. See lIASK, B, JFNKINS, J, etal.NACCARAIO, R. See BA1TTA(GLIA, G, D[ MARIO, F, et al.NANDA, R. See SARIN, S K, NANDA, R, et al.

See SARIN, S K, SETHI, K K, et al.NARDONE, G. See PARRILLI (G, CUOMO, R, et al.NARDUCCI, F, BASSOrI7, G, GABURRI, M, and MORELLI, A: Twenty fourhour manometric recording of colonic motor activity in healthyman, 17

NASIRY, R W, MCIN'I'OSH, J it, BY1H, K, and PIPFR, I) W: Prognosis ofchronic duodenal ulcer: a prospective study of the effects ofdemographic and environmental factors and ulcer healing, 533

Natural killer cells, HLA-DR expression and IgE containing cells injejunal mucosa of coeliac children, 988

NAYLOR, C P E. See CUMMINGS, J H, POMARE, E w, et al.

General index

Neodymium YAG laser palliation, endoscopic, for advancedmalignant dysphagia, 799-therapy, palliative, for malignant dysphagia, 792

Neonatal rat intestine, development of phospholipase A2 andlysophosphatidylcholine metabolising enzyme activities in, 822

Neoplasia, colorectal, experimental, plasminogen activators in, rolein adenoma-carcinoma sequence?, 816- , -, relationship to duodenal bile acids, 1454NEUMANN, J. See MERKI, H, WIlZEL, L, et at.Neurofibromatosis and small bowel adenocarcinoma, associationbetween (Case report), 1173-, von Recklinghausen's, achalasia-like disorder of oesophagus

in (Case report), 1522Neuromuscular and vascular hamartoma of small intestine as form

of Crohn's disease (Case reports), 1663Neuropathy, visceral, small intestinal motor responses to intra-

luminal distension in patient with, 714Neurotensin-like immunoreactivity after intestinal resection in rat,

1107Neutrophils, activated, enhanced release of leucotriene B4 from, in

chronic inflammatory bowel disease, 181free radical generation by, as potential mechanism of cellular

injury in acute alcoholic hepatitis, 1157News, 113,366, 508, 644, 780, 1192, 1325, 1552, 1692Nicardipine, intravenous, reduction of colonic motility in irritable

bowel syndrome by, 1609NIEDZWIECKI D. See ALLEN-MERSH, [G, KEMENY, N, et al.NIELSEN, F. See GUSIAFSEN, J, BOESBY, S, et al.NIELSEN, 0 H, AHNFELi-R0NNE, I, and ELMGREEN, J: Abnormalmetabolism of arachidonic acid in chronic inflammatory boweldisease: enhanced release of leucotriene B4 from activatedneutrophils, 181

NIELSEN, S E. See MANNICHE, C, MALCHOW-MOLLER, A, et al.Nifedipine, effect on gastric acid secretion and gastrin release, 455NILSSON, A. See THESLEFF, P, BENONI, C, et al.NISHIDA, 1, MIWA, H, SHIGEMATSU, A, YAMAMO'I'O, M, IIDA, M, and

FUJISHIMA, M: Increased arachidonic acid composition of phospho-lipids in colonic mucosa from patients with active ulcerativecolitis, 1002

Nitrosamine hypothesis of gastric carcinogenesis in precancerousconditions, evaluation of, and urinary N-nitrosoproline excretion,216

N-Nitrosoproline, urinary excretion, and evaluation of nitrosaminehypothesis of gastric carcinogenesis in precancerous conditions,216

NIWA, Y. See MIYACHI, Y, YOSHIOKA, A, et al.NOLAN, N P M, KELLY, C P, HUMPHREYS, J F H, COONEY, C, O'CONNOR, R,WALSH, r N, WEIR, D X, and O'BRIAIN, D S: An epidemic ofpseudomembranous colitis: importance of person to personspread, 1467

NORTHFIELD,T C. See CAYGILL, C P J, HILL, M J, et al.See CHAMBERS, J B, PRYCE, D, et al.See HALL, C N, KIRKHAM, i s, etal.

NORTHOVER, J M A See MELVILI E, D M, NOR'[HOVER, J M A, et al.NORTHWOOD, I. See BEEKEN, W, NORTHWOOD, t, et al.

O'BRIAIN, D S. See NOLAN, N P M, KEIIY, C P, et al.O'BRIEN, C J, WISE, R J S, O'GRADY, J G, and WIl.LIAMS, R: Neurological

sequelae in patients recovered from fulminant hepatic failure(Case reports), 93

O'BRIEN, J D, THOMPSON, D G, BURNHAM, W R, HOLLY, J, and WALKER, E:Action of centrally mediated autonomic stimulation on humanupper gastrointestinal transit: a comparative study of two stimuli,

OBTUtOWICZ, W. See KONTUREK, S J, BILSKI, J, et al.See KONTUREK, S J, KWIECIEN, N, et al.

O'CONNOR, R. See NOLAN, N P M, KELLY, C P, et al.ODES, H S, FRASER, D, and KRAWIEC, J: Ulcerative colitis in the Jewish

population of Southern Israel 1961-1985: epidemiological andclinical study, 1630

1709

O'DONOGHUE, D P. See AFDHAL, N H, LONG, A, et al.Oesophageal sphincter, lower, pressure in, effect of diaphragmatic

contraction, 1564-varices. See Varices, oesophagealOesophagitis, complicated, acid reflux patterns in, 1484

,importance of daytime gastro-oesophageal reflux in, 519reflux, ranitidine in treatment of, response predicted by

physiological studies?, 946Oesophagus, achalasia-like disorder of, in von Recklinghausen's

neurofibromatosis (Case report), 1522-, acidity, 24 hour, in achalasia before and after pneumatic

dilatation, 883,carcinoma of, palliation for (Leading article), 781manometric measurements, effectiveness for prediction of

oesophageal motor function, 940motility, scintigraphic assessment of (Letters), 363motor responses to intraluminal distension in normal subjects

and in oesophageal clearance disorders, 272pH monitoring (Leading article), 509

24 hour, ambulatory, in diagnosis of gastro-oesophageal reflux diseasc, 1145

,pressure activity, non-propagating, spontaneous, relationshipto acid gastro-oesophageal reflux in pathological and non-pathological refluxers, 1478

strictures of, benign, and tooth loss, 61; (Letters), 913ulcer, and colitis due to cytomcgalovirus in AIDS, clinical

manifestations and treatment with Foscarnet (Case reports), 482OETTILE, G J, and HEATON, K W: Is there a relationship betweensymptoms of the irritable bowel syndrome and objective measure-ments of large bowel function?: a longitudinal study, 146

OGAWA, K. See KUDO, H, INADA, M, et al.OGAWA, Y. See ONJI, M, KONDOH, H, et al.O'GRADY, J G. See O'BRIEN, C J, WISE, R J S, et al.OHSHIO, 6. See KUDO, H, INADA, M, et al.OHTA, Y. See ONJI, M, KONDOH, H, et al.OKUDA, S. See T[ASUTA, M, IISHI, H, et al.OLBE, L. See L.UNDELL, L, LINDSTEDT, G, et al.OLEKSY, J. See KON'I'UREK, S J, BILSKI, J, et al.

See KONJ'UREK, S J, KWIECIEN, N, et al.Olsalazine, effects in jejunum of rat, 346

, influence on gastrointestinal transit in ulcerative colitis, 1474OLSEN, B G. See S0RENSEN, V Z, OLSEN, B G, et al.OLSEN, J A, LOUD, F B, and CHRIS'I'IANSEN, J: Inhibition of meal

stimulated gastric acid secretion by an octapeptide somatostatinanalogue SMS 201-995, 464

OLSEN, P S, PEDERSEN, J H, POULSEN, S S, YAMASHITA, Y, andKIRKEGAARD, P: Neurotensin-like immunoreactivity afterintestinal resection in the rat, 1107

ONJI, M, KONDOH, H, HORIIKE, N, YAMAGUCHI, S, OGAWA, Y, KUMON, 1,and OHTA, Y: Effect of recombinant interleukin 2 on hepatitis B eantigen positive chronic hepatitis, 1648

OS'I', A. See 1.OFBERG, R, 'I'RIBUKAIT, B, et al.Osteoporosis in inflammatory bowel disease, 410OTAMIRI, T, FRANZfN, L, LINDMARK, D, and TAGESSON, C: Increased

phospholipasc A2 and decreased lysophospholipase activity in thesmall intestinal mucosa after ischaemia and revascularisation,1445

OWEN, R W. See GALLOWAY, DJ, JARRE'IT, F, et al.Oxygen species, reactive, generation of, effect of sulphasalazine and

mctabolites, 190; (Letters), 912, 913Oxytetracyclinc, effect on intestinal oestrogen metabolism and

plasma sex hormones in healthy men, 439

PAANANEN, A. See PUOILAKKAINEN, P, VALTONEN, v, et al.PABA test with p-aminosalicylic acid, improved specificity of, 468PALLONE, F, FAIS, S, SQUARCIA, 0, BIANCONE, L, POZZILLI, P, and

BOIRIVANT, M: Activation of peripheral blood and intestinal laminapropria lymphocytes in Crohn's disease: in vivo state of activationand in vitro response to stimulation as defined by the expression ofearly activation antigens, 745

1710

PALMER, K R. See PATIL, D H, WESI'ABY, D, et al.PALMER, R H. See KARLSTADT, R G, FRANK, W O, et al.Pancreatic enzyme discharge, in vitro stimulation by calcium, 1215

enzymes, serum concentrations, raised, in cigarette smokers,330

insufficiency, in vitro effect of duodenal juice on R binderscobalamin complexes in, correlation with cobalamin absorption,70

islets, human, pepsinogen C demonstration in, 1208polypeptide and gastric acid responses to modified sham

feeding, effects of truncal and parietal cell vagotomy, 280Pancreatitis, acute, carcinoid tumour of ampulla of Vater presenting

as (Case report), 1296emphysematous gastritis after (Case report), 900experimental, in rats, severity altered by antecedent

long term ethanol consumption combined with different diets, 64, severity of, assessment from C-reactive protein and

serum phospholipase A2, 764, chronic, biliary lipid metabolism in, influence of steatorrhoea,

1495,periampullary cyst as surgically remediable cause of (Case

reports), 358PARENTE, F. See BIANCHI PORRO, G, PARENTE, F, et al.Parenteral nutrition, effective intravenous cyclosporin therapy in

patient with severe Crohn's disease on (Case report), 1166PARR, N J, GRIME, J S, BAXTER, J N, CRITCHLEY, M, and MACKIE, C R:

Small bowel resistances and the gastroduodenal brake, 950PARRILLI, G, CUOMO, R, NARDONE, G, MAIO, G, IZZO, C M, and

BUDILLON, G: Investigation of intestine function during acute viralhepatitis using combined sugar oral loads, 1439

PARROITT, D M V. See BACA, M E, MOWAT, A MCI, et al.PARSONS, D S. See MOHSEN, A Q M, MULVEY, D, etal.PATERSON, Y J. See KAGNOFF, M F, PATERSON, Y J, et al.PATIL, D H, WESTABY, D, MAHIDA, Y R, PALMER, K R, REES, R, CLARK, M L,

DAWSON, A M, and SILK, D B A: Comparative modes of action oflactitol and lactulose in the treatment of hepatic encephalopathy,255

PAUMGARTNER, G. See SCHINDLBECK, N E, HEINRICH, C, et al.See S'FELLAARD, F, SAUERBRUCH, T, et al.

PEDERSEN, C. See MANNICHE, C, MALCHOW-M0LLER, A, et al.PEDERSEN, J H. See OLSEN, P S, PEDERSEN, J H, et al.PENA, A S. See BIEMOND, 1, LANGE, G G DE, et al.PENSTON, J, and WORMSLEY, K G: Achlorhydria: hypergastrinaemia:

carcinoids- a flawed hypothesis? (Progress report), 488; (Letters),1191, 1319

Pepsinogen C, demonstration in human pancreatic islets, 1208Peptic ulcer and non-steroidal anti-inflammatory drugs (Letters),

111cholelithiasis, and dyspepsia of unknown cause, clinical

presentation of 221 patients and discriminant value of dyspepticsymptoms, 40

, decline in, dietary essential fatty acids as factor in(Letters), 914, 915

gastric surgery for, cancer after (Leading article), 921increased risk of cancer at multiple sites

after, 924,ginger and carbon dioxide as thromboxane synthetase

inhibitors for (Letter), 1323-, life threatening complications of, and non-steroidal anti-

inflammatory drugs, 527treatment in patients with rheumatic disease, influence of

non-steroidal anti-inflammatory drugs (Clinical trial), 226Peptide YY, effect on mouth-to-caecum transit time, 166Periampullary cyst as surgically remediable cause of pancreatitis

(Case reports), 358PErERS, T J. See BJARNASON, i, and PETERS,T J

See BJARNASON, I, WILLIAMS, P, et al.PETRAS, R E. See SARRE, R 0, FROST, A G, et al.PETRILLO, M. See BIANCHI PORRO, G, and PETRILLO, M

Phagocytes in cell suspensions of colon mucosa, 976

General index

PHII LIPS, G W L. See GUPTA, S, BARIER, s, et al.PHILLIPS, S: The gut is a membrane, is a vesicle, is a gut! (Leading

article), 650PHILLIPS, S F. See STONNINGI1ON, C M, PHILLIPS, S F, et al.Phospholipase A2 activity, increased, and decreased lysophospholi-

pase activity in small intestinal mucosa after ischaemia andrevascularisation, 1445

and lysophosphatidylcholine metabolising enzyme activi-ties, development in neonatal rat intestine, 822

in serum and C-reactive protein in assessment of severityof acute pancreatitis, 764

Phospholipids, increased arachidonic acid composition in colonicmucosa in active ulcerative colitis, 1002

Phosphonoformate. See FoscarnetPIASTUCKI, I. See KONTIUREK, S J, RADECKI, T, et al.PICCOLI, A. See BA'ITAGLIA, G, Di MARIO, F, et al.PINCHING, A J. See WEBER, J N, THOM, s, et al.PIPER, D W. See NASIRY, R W, MCINTOSH, I H, et al.

SeeTIALLEY, NJ, MCNEIL, D, etal.Pirenzepine, healing effect in erosive gastritis, trial of, and relation-

ship of disease to acid secreting area and intestinal metaplasia,561; (Letters), 1321, 1322

inferior in potency to telenzepine, dose response and compara-tive secretory study in man, 888

Plasma platelet factor 4 concentrations, raised, in Crohn's disease,336

sex hormones and intestinal oestrogen metabolism in healthymen, effect of oxytetracycline, 439

Plasminogen activators in experimental colorectal neoplasia, role inadenoma-carcinoma sequence?, 816

Platelet factor 4, plasma concentrations, raised, in Crohn's disease,336

Polymer coating, effect on faccal recovery of ingested 5-aminosalicylic acid in ulcerative colitis, 1084

Polyposis, adenomatous, familial, biliary tract pathology in, assess-ment of (Letters), 1320

gastric and duodenal polyps in, nature and preval-ence, 306

Polyps, colonic, primary, and polyps synchronous with colorectalcancer, immunohistochemical Ca 19-9 in, 594; (Reprint), 1049

POMARE, E W. See CUMMINGS, J H, POMARE, E w, et al.POON, G P. See LAU, W Y, FAN, S T, et al.POPIELA, T. See KONTUREK, S J, KWIECIEN, N, etal.-. See KONTUREK, S J, POPIELA, T, et al.Porphyrin metabolism and haem biosynthesis in Gilbert's syn-drome, 125-in Gilbert's, Dubin-Johnson, and Rotor's syndromes

(Letters), 1548, 1549Portal fibrosis, non-cirrhotic, and cirrhosis of liver, measurementand correlation of wedged hepatic, intrahepatic, intrasplenic andintravariceal pressures in, 260

hypertension, gastric mucosa in (Letter), 1324in biliary disease, development of, role of liver atrophy,

hepatic resection and hepatocyte hyperplasia in, 1022pressure, shunting and blood flow, changes during develop-

ment of cirrhosis in response to beta-blockade, 663systemic encephalopathy, chronic, update 1987 (Progres.s

report), 1043venous obstruction, extrahepatic (Leading article, 1193

, spontaneous (natural) splenoadrenorenalshunts in, 20 cases of, 1198

PORTMANN, B. See FORBES, A, PORTMANN, B, etal.POULSEN, S S. See OLSEN, P S, PEDERSEN, J H, et al.

See SZECSI, P B, HAt GREEN, H, et al.POZZILLI, P. See PALLONE, F, FAIS, s, et al.Prednisolone enemas in treatment of ulcerative colitis, comparison

with sodium cromoglycate enemas (Clinical trial), 88; (Letter),1323

,oral, in vivo effects on prostaglandin and leucotriene produc-tion in ulcerative colitis, 1095

General index

PRIDDLE, J D. See BARR, G D, HUDSON, MJ, et al.See GUAN, R, RAWC[LIFFE, P M, et al.See MOHSEN, A Q M, MULVEY, D, et al.

PRIOR, A, HARRIS, S R, and WHORWELL, P J: Reduction of colonicmotility by intravenous nicardipine in irritable bowel syndrome,1609

, and WHORWELL, P J: Double blind study of ispaghula in irritablebowel syndrome (Clinical trial), 1510

See also WHORWELL, P J, PRIOR, A, et al.Proctalgia fugax, oral clonidine for (Case report), 1039Propionate absorption and metabolism in rabbit hindgut, 1077Prostaglandin and leucotriene production in ulcerative colitis, in

vivo effects of oral prednisolone, 1095dependent mechanism for De-Nol stimulation of gastric and

duodenal alkaline secretion, 1557E2 and bicarbonate output by normal human stomach, effect of

luminal pH, 1291participation in purinergic neurotransmission of gut, 1605

Prostaglandins and NSAIDs, effect on permeability of human smallintestine, statistical assessment (Letters), 777

? endogenous, role in gastrocytoprotection by colloidal bismuthsubcitrate (De-Nol) and sucralfate, 201; (Letter), 1322

, renal, and haemodynamics, relation to renal function infulminant hepatic failure, 1643

Protein losing enteropathy due to intestinal schistosomiasis (Casereport), 616

PRUDHAM, D. See BARDHAN, K D, THOMPSON, M, et al.PRYCE, D. See CHAMBERS, J B, PRYCE, D, et al.PRYDE, A. See DE CAESIECKER, J S, BLACKWELL, J N, et al.

See KING, P M, PRYDE, A, etal.Pseudomelanosis, duodenal, clinical and ultrastructural studies in

(Case reports), 1673Pseudomembranous colitis, epidemic of, importance of person to

person spread in, 1467Pseudopolycythaemia and coeliac disease (Case reports), 1041Psychiatric illness and life events, relation to irritable bowelsyndrome, 160

in inflammatory bowel disease, 1600Psychological factors in irritable bowel syndrome (Progress report),

1307Psychosocial sequelae of stoma surgery for inflammatory bowel

disease in childhood, 1257Pteroyltriglutamate deconjugation to folic acid, enterocyte function

in progressive systemic sclerosis as estimated by, 435PUOLAKKAINEN, P, VALTONEN, V, PAANANEN, A, and SCHRODER, T:

C-reactive protein and serum phospholipase A2 in the assessmentof the severity of acute pancreatitis, 764

Purinergic neurotransmission of gut, prostaglandin E2 participationin, 1605

QAMAR, M I, and READ, A E: Effects of exercise on mesenteric bloodflow in man, 583

QUIRKE, P. See FOZARD, J B J, QUIRKE, P, etal.

RADECKI, T. See KONTUREK, S J, RADECKI, T, et al.RADHA, V. See DAS, U N, REDDY, D N, etal.RAINFORD, D J. See BLOODWORIH, L L, STEVENS, P E, et al.RAIlI, c. See CORINALDESI, R, STANGHELLINI, v, et al.RALPHS, D N L. See SPILLER, R C, LEE, Y c, et al.RALSTON, M. See BIGGS, B A, CROWE, S M, et al.RAMAGE, J K. See DEAKIN, M, GLENNY, H P, etal.RAMO, o J: Antecedent long term ethanol consumption in combina-

tion with different diets alters the severity of experimental acutepancreatitis in rats, 64

RAMSDEN, C W. See MONSON, J R T, RAMSDEN, c w, et al.Ranitidine and cimetidine, dose related in vitro effects on basal andACTH-stimulated steroidogenesis (Letters), 1688, 1690

bedtime, effect on overnight gastric acid output and intra-gastric pH, dose/response study and comparison with cimetidine,294

1711

in treatment of reflux oesophagitis, response predicted byphysiological studies?, 946

150 mg at night in prevention of gastric ulcer relapse, 4601 year's treatment with, and truncal vagotomy, effects on

gastric contents, 726, single dose treatment, bedtime administration too late?, 451

RAO, P N. See DAS, U N, REDDY, D N, et a!.RAO, S S C, READ, N W, and HOLDSWORTH, C D: Influence of olsalazineon gastrointestinal transit in ulcerative colitis, 1474

Is the diarrhoea in ulcerative colitis related toimpaired colonic salvage of carbohydrate?, 1090

RASK-MADSEN, J. See LAURITSEN, K, LAURSEN, L s, et al.RASMUSSEN, S N. See MANNICHE, C, MALCHOW-M0LI ER, A, etal.RAWCLIFFE, P M. See GUAN, R, RAWCLIFFE, P M, et al.RAWLINGS, J M. See MCLAUCHLAN, G, RAWLINGS, J M, et al.R-binder. See Vitamin B12 R-binderREA, E. See CORINALDESI, R, STANGHELLINI, V, et al.READ, A E. See QAMAR, M i, and READ, A E

READ, N w: Functional gastroenterological disorders: the name's thething ... (Leading article), 1

See also BANNISIER, J J, ABOUZEKRY, L, et al.See also BANNISTER, J J, DAVISON, P, et al.See also BANNISTER, J J, GIBBONS, C, etal.See alSo BROWN, N J, RUMSEY, R D E, etal.See also EDWARDS, C A, HOLDEN, s, et al.See also HOUGHTON, L A, HICKSON, F, etal.See also RAO, S S C, READ, N W, et al.

RECORD, C O. See AL MARDINI, H, LINDSAY, D C, et al.Rectal distension, modulation of upper gastrointestinal motility by,864

ulcer, solitary, pressure and prolapse as cause of, 1228Rectum, mucosa of, in men with and without HIV infection,immunological study of, 1619

, spirochaetosis of, associated with intraepithelial mast cell andIgE plasma cell response, 2 cases of, 588

REDDY, D N. See DAS, U N, REDDY, D N, et al.REES, H C. See THOMPSON, J N, SALEM, R R, etal.REES, R. See PA'I'IL, D H, WESIABY, D, et al.REES, W D W: Mucus bicarbonate barrier- shield or sieve (Leading

article), 1553See also CRAMPTON, J R, GIBBONS, L C, et al.See also MASTROPAOLO, G, and REES, W D W

REES, Y. See JENKINS, D, RICHARDS, J E, et al.Reflux, acid, patterns in complicated oesophagitis, 1484

,gastro-oesophageal, acid, relationship to spontaneous non-propagating pressure activity in oesophagus in pathological andnon-pathological refluxers, 1478

and migrating motor complex, 929daytime, importance in oesophagitis, 519pathological, diagnosis of, ambulatory 24 hour intra-

oesophageal pH-monitoring in, 1145, transpyloric fluid movement and antroduodenal motility

in patients with, 545oesophagitis, ranitidine in treatment of, response predicted by

physiological studies?, 946of bile equal in healthy controls and gastric ulcer patients, 1577

REICHARD, H. See LOFBERG, R, TRIBUKAIT, B, et al.REID, E M. See compsrON J F, 0JUDD, D, et al.REINERS, C. See FISCHBACH, W, BECKER, W, et al.Renal function in fulminant hepatic failure, relation to haemo-dynamics and renal prostaglandins, 1643

RENVALL, H. See BORCH, K, RENVALL, H, et al.REPOND, F. See HEER, M, REPOND, F, et al.Respiratory tract, Crohn's disease involving (Case reports), 1669REY, M-A. See ROULOT, D, VALLA, D, et a!.REYNOLDS, J. See LAMONT, G, EVANS, D, et al.Rhamnose/lactulose permeability, abnormal, in active Crohn's

disease of small bowel, improvement by elemental diet, 1073Rheumatic disease, peptic ulcer treatment in patients with, influence

of non-steroidal anti-inflammatory drugs (Clinical trial), 226

1712

RHODES, J. See COMPSTON, J E, JUDD, D, et al.See MYERS, B, EVANS, D N w, et al.

RICHARDS, D. See MYERS, B, EVANS, D N W, etal.

RICHARDS, H K. See FLOWERDEW, A D S, RICHARDS, H K, et al.

RICHARDS, J E. See JENKINS, D, RICHARDS, J E, et al.

RICHARDSON, C T, and FELDMAN, M: Transdermal scopolamine andgastric acid secretion (Letter), 1687

RICHARDSON, R. See BROWN, A M, BRADSHAW, M J, et al.

RICHENS, A. See MYERS, B, EVANS, D N W, et al.

RIECKEN, E O. See ZEITZ, M, HOPF, U, et al.

RILEY, S A, LECARPENTIER, J, MANI, V, GOODMAN, M J, MANDAL, B K, and

TURNBERG, L A: Sulphasalazine induced seminal abnormalities inulcerative colitis: results of mesalazine substitution, 1008

RING-LARSEN, H. See HENRIKSEN, J H, RING-LARSEN, H, et al.

RITrER, C VON. See BAUERFEIND, P, CILLUFFO, T, et al.

ROBB, T A. See DAVIDSON, G P, and ROBB, T A

ROBERTSON, D A F, ALDERSLEY, M A, SHEPHERD, H, LLOYD, R s, and

SMITH, C L: H2 antagonists in the treatment of reflux oesophagitis:can physiological studies predict the response?, 946

,and SMITH, C L: Patterns of acid reflux in compli-cated oesophagitis, 1484

ROBINSON, P. See HOSKING, S W, ROBINSON, P, et al.

ROCHESTER, D F. See MIri-iAL, R K, ROCHESTER, D F, et al.

ROE, R, FERMOR, B, and WILLIAMSON, R C N: Proliferative instabilityand experimental carcinogenesis at colonic anastomoses, 808

ROELS, H. See CUVELIER, C, BARBATIS, c, et al.

ROGERS, K. See FINCH, P J, RYAN, F P, et al.

ROHMEL, J. See MERKI, H, WI1-ZEL, L, et al.ROS, E, and ZAMBON, D: Postcholecystectomy symptoms: a prospec-

tive study of gall stone patients before and two years after surgery,

1500Rotor's, Gilbert's and Dubin-Johnson syndromes, porphyrin meta-

bolism in (Letters), 1548, 1549ROULOT, D, VALLA, D, BRUN-VEZINET, F, REY, M-A, CLAVEI., F, DEGOTT,

C, GUILLAN, J, VERDURON, J, RUEFF, B, and BENHAMOU, J-P:

Cholangitis in the acquired immunodeficiency syndrome: reportof two cases and review of the literature (Case reports and review),1653

ROWE, P H, J-AYLOR, P R, and MASON, R C: Gastric cytoprotection bycolloidal bismuth subcitrate (De-Nol) and sucralfate: role ofendogenous prostaglandins (Letter), 1322

RUBEN, A T. See VAN BERGE HENEGOUWEN, G P, VAN DER WERF, S D J,

et al.RUEFF, B. See ROULOT, D, VALLA, D, et al.RUMSEY, R D E. See BROWN, N J, RUMSEY, R D E, etal.Runner, long distance, female, bloody diarrhoea due to acute

ischaemic colitis in (Case report), 896RUSSELL, C 0 H, and WHELAN, G: Oesophageal manometry: how well

does it predict oesophageal function, 940RYAN, F P. See FINCH, P J, RYAN, F P, et al.

SACHDEV, G K. See SARIN, S K, NANDA, R, et al.See SARIN, S K, SACHDEV, G K, et al.

SAGRADA, A, FARGEAS, M J, and BUENO, L: Involvement of alpha-I andalpha-2 adrenoceptors in the postlaparotomy intestinal motordisturbances in the rat, 955

SAKAMOTO, K, HAGA, Y, YOSHIMURA, R, EGAMI, H, YOKOYAMA, Y, and

AKAGI, M: Comparative effectiveness of the tumour diagnostics,CA 19-9, CA 125 and carcinoembryonic antigen in patients withdiseases of the digestive system, 323

SALEM, R R. See THOMPSON, J N, SALEM, R R, et al.SALGEMINI, R. See CORINALDESI, R, STANGHELLINI, v, et al.

Salicylate, exacerbation of ulcerative colitis induced by (Casereports), 613

SANDERSON, I R, BOULTON, P, MENZIES, I, and WALKER-SMITH, J A:

Improvement of abnormal lactulose/rhamnose permeability inactive Crohn's disease of the small bowel by an elemental diet,1073

SANDLE, G I, and MCGLONE, F: Acute effects of dexamethasone on

cation transport in colonic epithelium, 701

General index

Sarcoma, hepatic, in adults, 25 cases reviewed, 668Kaposi's, AIDS-related, presenting as ulcerative colitis and

complicated by toxic megacolon (Case report), 1302SARIN, S K, NANDA, R, SACHDEV, G K, CHARt, S, ANAND, B s, and BROOR,

S L: Intravariceal versus paravariceal sclerotherapy: a prospectivc,controlled, randomised trial, 657

, SACHDEV, G K, and ANAND, B S: Endoscopic sclerotherapy usingabsolute alcohol (Letter), 777

,SETHI, K K, and NANDA, R: Measurement and correlation ofwedged hepatic, intrahepatic, intrasplenic and intravaricealpressures in patients with cirrhosis of liver and non-cirrhotic portalfibrosis, 260

See also KUMAR, A, KUMAR, N, etal.SARNA, S K. See KARAUS, M, SARNA, S K, et al.SARRE, R G, FROST, A (i, JAGELMAN, D G, PETRAS, R E, SIVAK, M V,and MCGANNON, E: Gastric and duodenal polyps in familialadenomatous polyposis: a prospective study of the nature andprevalence of upper gastrointestinal polyps, 306; (Letter, byJagelman), 1320

SAUERBRUCH, 1'. See SJ-ELLAARD, F, SAUERBRUCIt, T, et al.SAUNDERS, J R. See BA'I-', R M, HART, C A, et al.SAVAGE, A P, ADRIAN, T E, CAROLAN, G, CFIAI1ERJEE, V K, and BLOOM,

S R: Effects of peptide YY on mouth to caecum intestinal transittime and on the rate of gastric emptying in healthy voluntcers,166- , MArIHEWS, J L, GHAI-EI, M A, COOKE, T, and BLOOM, S R:

Enteroglucagon and experimental intestinal carcinogenesis in therat, 33

SAVAGE, F. See GELISI'ER, J S K, LEWIN, M R, et al.SAVILAHTI, E. See ARATO, A, SAVILAHJI, E, et al.SAXENA, A. See VINAYAK, V K, SAXENA, A, et al.SCHEURLE, E. See MERKI, H, WITZEL, L, et al.SCHINDLBECK, N E, HEINRICH, C, STELLAARD, F, PAUMGAR'I'NER, G, and

MUI.LER-LISSNER, S A: Healthy controls have as much bile reflux asgastric ulcer patients, 1577

Schistosomiasis, intestinal, protein losing enteropathy due to (Casereport), 616

SCHRODER, T. See PUOLAKKAINEN, P', VALTONEN, V, et al.SCIARREITA, 0, FAGIOLI, G, FURNO, A, VICINI, G, CECCHEITI, L, GRIGOLO,

B, VERRI, A, and MALAGUTI, P: 75Se HCAT test in the detection ofbile acid malabsorption in functional diarrhoea and its correlationwith small bowel transit, 970

Scintigraphic assessment of oesophageal motility (Letters), 363Sclerosis, systemic, progressive, enterocyte function as cstimated by

deconjugation of pteroyltriglutamate to folic acid in, 435,-intestinal involvement detected by increased

unconjugated serum bile acids in, 446Sclerotherapy, endoscopic, using absolute alcohol (Letter), 777

variceal (Leading article), 645, intravariceal and paravariceal techniques of, compara-

tive trial, 657Scopolamine, transdermal, and gastric acid secretion in duodenal

ulcer (Letters), 1686, 168779SeHCAT test in detection of bile acid malabsorption in functional

diarrhoea and correlation with small bowel transit, 970SELLERS, L A, ALLEN, A, and BENNE-r[, M K: Formation of a fibrin bascd

gelatinous coat over repairing rat gastric epithelium after acutcethanol damage: interaction with adherent mucus, 835

Seminal abnormalities in ulcerative colitis induced by sulpha-salazine, effect of mesalazine substitution, 1008

SENDA, S, FUJIYAMA, Y, and HOSODA, S: IgA protease-producingbacteria in patients with ulcerative colitis (Letter), 917

Serotonin, effect on rat ileal transport, cisapride inhibition of,evidence for involvement of 5-HT2 receptors in, 844

Serum bile acids, unconjugated, increase in, intestinal involvementin progressive systemic sclerosis detected by, 446CEA concentration, fall after cytotoxic chemotherapy for

disseminated colorectal cancer, significance of, 1625-pancreatic enzyme concentrations, raised, in cigarette

smokers, 330

General index

phospholipase A2 and C-reactive protein in assessment ofseverity of acute pancreatitis, 764

SETHI, K K. See SARIN, S K, SETHI, K K, et al.Sex hormones, plasma levels, and intestinal oestrogen metabolism

in healthy men, effect of oxytetracycline, 439SHAKLAI, M. See KONIKOFF, F, MOR, C, et al.SHALTOUT, A A. See KHUFFASH, F A, BARAKAT, M H, et al.SHAPOWAL, S W. See KARLSTADT, R G, FRANK, W O, et al.SHEPHERD, H. See ROBERTSON, D A F, ALDERSLEY, M A, et al.SHEPHERD, N A, and JASS, J R: Neuromuscular and vascularhamartoma of the small intestine: is it Crohn's disease? (Casereports), 1663-. See also MELVILLE, D M, NORTHOVER, J M A, et al.SHERLOCK, S: Chronic portal systemic encephalopathy: update 1987

(Progress report), 1043SHIELDS, R. See BAXTER, J N, GRIME, J S, et al.SHIGEMATSU, A. See NISHIDA, T, MIWA, H, et al.SHINOZUKA, K. See CHENG, J T, and SHINOZUKA, KSHOKOUH-AMIRI, M H. See JENSEN, S L, HOLST, J J, et al.SHU, S. See HSIEH, K H, SHU, S, et al.SHURGOT, B. See ALLEN-MERSH, T G, KEMENY, N, et al.SILK, D B A. See PATIL, D H, WESTABY, D, et al.

See SPILLER, R C, JONES, B J M, et al.See SPILLER, R C, LEE, Y C, et al.

SIMI, M, LEARDI, S, TEBANO, M T, CASTELLI, M, COSIANTINI, F M, andSPERANZA, v: Raised plasma concentrations of platelet factor 4 inCrohn's disease, 336

SIVAK, M v. See SARRE, R G, FROST, A G, et al.SKIDMORE, C. See KRASNER, N, BARR, H, et al.SLEVIN, B. See SMART, H L, FOSTER, P N, et al.SIOWIACZEK, M. See KONTUREK, S J, POPIELA, T, et al.SMART, H L, FOSTER, P N, EVANS, D F, SLEVIN, B, and ATKINSON, M:Twenty four hour oesophageal acidity in achalasia before andafter pneumatic dilatation, 883

SMETHURST, P. See BJARNASON, I, WILLIAMS, P, etal.SMITH, C L. See ROBERTSON, D A F, ALDERSLEY, M A, et al.SMITH, M W. See CHAVES, M, SMITH, M w, et al.SMITH, P L R. See THOMAS, J M, MISIEWICZ, J J, et al.SMITH, P M: Variceal sclerotherapy: further progress (Leading

article), 645Smokers and non-smokers with and without duodenal ulcer, com-

parison of maximal gastric secretion in, 557,cigarette, raised serum pancreatic enzyme concentrations in,

330Smoking, influence on effect of histamine H2-receptor antagonistson intragastric acidity, trial of, 549

SMS 201-995, inhibition of meal stimulated gastric acid secretion by,464

Sodium content, importance in jejunal water and electrolyte absorp-tion from 2 enteral feeds, 681

Sodium cromoglycate enemas in treatment of ulcerative colitis,comparison with prednisolone enemas (Clinical trial), 88;(Letter), 1323

SOFTLEY, A. See DE DOMBAL, F T, and SOFTLEY, ASOLCIA, E. See BORDI, C, CREUTZFELDT, w, et al.Somatostatin analogues. See SMS 201-995

and gastrin, antral release in anaesthetised, atropinised duo-denal ulcer patients and controls, effect of intragastric pH, 206

SORENSEN, V Z, OLSEN, B G, and BINDER, V: Life prospects and qualityof life in patients with Crohn's disease, 382

SPENCER, J. See THOMPSON, J N, SALEM, R R, et al.SPERANZA, V. See SIMI, M, LEARDI, s, et al.Sphincter, oesophageal, lower, pressure in, effect of diaphragmatic

contraction, 1564Sphincterotomy, endoscopic, and surgical approaches in treatment

of 'sump syndrome', 142SPILLER, R C, JONES, B J M, and SILK, D B A: Jejunal water and

electrolyte absorption from two proprietary enteral feeds in man:importance of sodium content, 681

, LEE, Y C, EDGE, C, RALPHS, D N L, STEWART, J S, BLOOM, S R, and

1713

SILK, D B A: Delayed mouth-caecum transit of a lactulose labelledliquid test meal in patients with steatorrhoea caused by partiallytreated coeliac disease, 1275

Spirochaetosis of rectum associated with intraepithelial mast celland IgE plasma cell response, 2 cases of, 588

Splenoadrenorenal shunts, spontaneous (natural), in extrahepaticportal venous obstruction, 20 cases of, 1198

SQUARCIA, O. See PALLONE, F, FAIS, S, et al.S'rALDER, G A. See MARBET, U A, STALDER, G A, et al.STAMATAKIS, G. See MORRIS, D L, CHINNERY, J B, et al.STAMFORD, I F. See BENNETT, A, CIVIER, A, et al.STANGHELLINI, V, CAMILLERI, M, and MALAGELADA, J-R: Chronic

idiopathic intestinal pseudo-obstruction: clinical and intestinalmanometric findings, 5

See also CORINALDESI, R, S'ANGHELLINI, V, eta!.Starch microspheres, degradable, for liver metastases in rat model,temporary blood flow stasis with, 1201

STAUN, M: Distribution of the 10000 molecular weight calciumbinding protein along the small and large intestine of man, 878

SI-AVE, R. See VALNES, K, BRANDTZAEG, P, et al.Steatorrhoea caused by partially treated coeliac disease, delayedmouth-to-caecum transit of lactulose labelled liquid test meal inpatients with, 1275

,influence on biliary lipid metabolism in chronic pancreatitis,1495

, mixed endocrine adrenal tumour causing (Case report), 1298STELLAARD, F, SAUERBRUCH, I, LUDERSCHMIDT, C, LEISNER, B, and

PAUMGARTNER, G: Intestinal involvement in progressive systemicsclerosis detected by increased unconjugated serum bile acids, 446

See also SCHINDLBECK, N E, HEINRICH, C, et al.STEPHEN, A M, WIGGINS, H s, and CUMMINGS, J H: Effect of changing

transit time on colonic microbial metabolism in man, 601STERN, S. See KONIKOFF, F, MOR, c, et al.Steroidogenesis, basal and ACTH-stimulated, dose related in vitro

effects of cimetidine and ranitidine (Letters), 1688, 1690STEVENS, P E. See BLOODWORTH, L L, STEVENS, P E, et al.STEWART, J S. See SPILLER, R C, LEE, Y C, et al.SI-EWART, M. See FOSTER, P N, STEWART, M, et al.STOCKBRUGGER, R W: Vagal control of gastric alkaline (Letter), 1687Stoma surgery for inflammatory bowel disease in childhood, psycho-

social sequelae of, 1257Stomach, human, normal, bicarbonate and prostaglandin E2 output,

effect of luminal pH, 1291See also Gastric

Stomach-to-caecum transit. See Gastrointestinal transitSTONNINGTON, C M, PHILLIPS, S F, MELTON, L J, III, and ZINSMEISTER, A R:

Chronic ulcerative colitis: incidence and prevalence in acommunity, 402

, ZINSMEISTER, A R, and MELTON, L J, III: Prognosis ofchronic ulcerative colitis in a community, 1261

Stool size and consistency, effect on defecation, 1246Sucralfate and colloidal bismuth subcitrate (De-Nol), gastrocyto-

protection by, and role of endogenous prostaglandins, 201;(Letter), 1322

Sugar oral loads, combined, investigation of intestinal functionduring acute viral hepatitis using, 1439

SULLIVAN, s, and TROSTER, M: Eosinophilic colitis (Letter), 506Sulphasalazine and metabolites, effect on generation of reactiveoxygen species, 190; (Letters), 912, 913-, seminal abnormalities in ulcerative colitis induced by, effect of

mesalazine substitution, 1008SULSER, H. See HEER, M, REPOND, F, et al.'Sump syndrome', endoscopic sphincterotomy and surgical

approaches in treatment of, 142SUNDLER, F. See BORDI, C, CREUTZFELDT, w, et al.-. See THESLEFF, P, BENONI, C, et al.SUTHERLAND, I H. See KANG, J Y, WU, A Y T, et al.SVEHAG, S-E. See HUSBY, S, FOGED, N, etal.SWAIN, C P. See BOWN, S G, HAWES, R, et al.SWAIN, R: Oral clonidine for proctalgia fugax (Case report), 1039

1714 General index

Sympathetic nervous activity, hepatic intestinal, enhanced,evidence of, in hepatic intestinal uptake and release of catechola-mines in alcoholic cirrhosis, 1637

SZECSI, P B, HALGREEN, H, POULSEN, S S, AXELSSON, C K, DAMKJAER-NIELSEN, M, KJiER, T, and FOLTMANN, B: Demonstration ofpepsinogen C in human pancreatic islets, 1208

'I'AGE-JENSEN, U. See MANNICHE, C, MALCHOW-M0LLER, A, et al.'I'AGESSON, C, TELIEMO, E, EKSTROM, G, and WESIROM, B: Development

of phospholipase A, and lysophosphatidylcholine metabolisingenzyme activities in the neonatal rat intestine, 822-. See also OTAMIRI, T, FRANZEN, L, et al.IAINIO, V-M. See ARATO, A, SAVILAHTI, E, et al.'I'AIT, G w, and MCKINLAY, A w: Teeth and benign oesophageal

stricture (Letter), 913J'ALLEY, N I, MCNEIL, D, and PIPER, D w: Discriminant value of

dyspeptic symptoms: a study of the clinical presentation of 221patients with dyspepsia of unknown cause, peptic ulceration, andcholelithiasis, 40

IARNAWSKI, A S. See HOLLANDER, D, and TARNAWSKI, A STARP, U. See LARSEN, B, TARP, U, et al.IArSUrA, M, IISHI, H, and OKUDA, S: Relationship of erosive gastritis

to the acid secreting area and intestinal metaplasia, and thehealing effect of pirenzepine, 561; (Letter, by Tatsuta), 1322

'I'AYLOR, I. See FLOWERDEW, A D S, RICHARDS, H K, et al.-. See MCLAREN, M, BRAYE, S, et al.IAYLOR, P R. See ROWE, P H, TAYLOR, P R, et al.TEBANO, M T. See SIMI, M, LEARDI, s, et al.Teeth, loss of, and benign oesophageal stricture, 61; (Letters), 913TELEMO, E. See TAGESSON, C, TELEMO, E, et al.Telenzepine superior in potency to pirenzepine, dose response and

comparative secretory study in man, 888Tetracycline, single dose, in cholera (Clinical trial), 1029FHEODOR, E. See KONIKOFF, F, MOR, C, et al.IHESLE-FF, P, BENONI. C, MARTENSSON, H, NILSSON, X, SUNDLER, F, andAKESSON, B: A mixed endocrine adrenal tumour causing steatorr-hoca (Case report), 1298

'I'HOM, S. See WEBER, J N, THOM, S, et al.l'HOMAS, J M, MISIEWICZ, J J, COOK, A R, HILL, M J, SMITH, P L R,

WALTERS, C L, FORSIFER, J K, MARTIN, L E, and WOODINGS, D F: Effectsof one year's treatment with ranitidine and of truncal vagotomy ongastric contents, 726

'IHHOMPSON, D G. See KENDALL, G P N, 'I'HOMPSON, D O, et al.See O'BRIEN, J D, 1'HOMPSON, D G, et al.

THOMPSON, G G. See BIRNIE, G G, THOMPSON, G G, et al.See MCCOLL, K E L, THOMPSON, G G, et al.

THOMPSON, I L. See BIGGS, B A, CROWE, S M, et al.1'HOMPSON, J N, SALEM, R R, HEMINGWAY, A P, REES, H C, HODGSON,

H J F, WOOD, C B, ALLISON, D j, and SPENCER, J: Specialistinvestigation of obscure gastrointestinal bleeding, 47

1lHOMPSON, M. See BARDHAN, K D, THOMPSON, M, et al.'I'HOMPSON, M H. See BARDHAN, K D, THOMPSON, M, et al.1HOMPSON, R P H. See MAXTON, D G, AINLEY, c c, et al.

See MAXTON, D G, CYNK, E U, etal.See MAXTON, D G, and THOMPSON, R P H

1'HOMSON, T J. See ALLAM, B F, TILLMAN, J E, et al.-. See BARDHAN, K D, THOMPSON, M, et al.1JHOR, P. See KONTUREK, S J, KWIECIErN, N, et al.Thromboxane synthesis, selective inhibition by dazmegrel for

gastric mucosal protection, 541Thromboxane synthetase inhibitors (ginger and carbon dioxide) for

peptic ulceration (Letter), 1323I'ILLMAN, J E. See ALLAM, B F, TILLMAN, J E, et al.TIMMER, E. See HOEK, F J, BERGH, F A J 'I' M VAN DEN, et al.1IMMS, i M. See BANNISTER, J J, DAVISON, P, et al.TOBBIA, 1. See AFDHAL, N H, LONG, A, et al.TOBIN, M V. See CRAMPION, J R, TOBIN, M v, et al.Transpyloric fluid movement and antroduodenal motility in patients

with gastro-oesophageal reflux, 545

Trials, clinical, reporting of, need for confidence intervals in(Letters), 916, 1549

TRIBUKAIT, B. See LOFBER6, R, IRIBUKAIT, B, et al.TRIGER, D R: Extra hepatic portal venous obstruction (Leadinig

article), 1193'14C-Triolein absorption test in diagnosis of fat malabsorption, 694

breath test (Letter), 1320Tripotassium dicitrato bismuthate. See De-NolTROSTER, M. See SULLIVAN, s, and TROSrER, M

TRYPHONOS, M. See ARCHIMANDRITIS, A, TZIVRAS, M, et al.Tumour, adrenal, endocrine, mixed, causing steatorrhoca (Case

report), 1298carcinoid, of ampulla of Vater presenting as acute pancreatitis

(Case report), 1296diagnostics in gastrointestinal diseases, comparative effective-

ness of CA 19-9, CA 125 and CEA, 323Tumours, carcinoid, gastric, achlorhydria and hypergastrinaemia as

causal sequence for, reassessment of (Progress report), 488;(Letters), 1189, 1191, 1319

TUNGEKAR, M F. See KHUFFASH, F A, BARAKAI, M H, et al.TURNBERG, L A. See MORIARI'Y, K J, HIGGS, N B, etal.

See RILEY, S A, LECARPENItiER, J, et al.I'URNER, J M, LAWRENCE, S, FELLOWS, I W, JOHNSON, 1, HILL, I' (i, and

HOLMES, G K T: ["4CJ-triolein absorption: a useful test in thediagnosis of malabsorption, 694

TYRRELL, L D J. See DAN, M, TYRRELL, L D J, et al.iYI7GAT, G N J. See HOEK, F J, BERGH, F A J T M VAN DEN, et al.TZIVRAS, M. See ARCHIMANDRITIS, A, IZIVRAS, M, et al.

Ulcer. See under Duodenum; Gastric; Oesophagus; PepticUNSWORTH, D J. See KAGNOFF, M F, I'Al'ERSON, Y J, et al.UNWIN, R. See WEBER, J N, H(HOM, s, etal.Urogastrone-EGF, intravenous (but not intragastric), trophic cffecton intestine of parenterally fed rats, 573

Vagal cholinergic control of gastric alkaline secretion in normalsubjects and in duodenal ulcer, 739; (Letters), 1687

stimulation and gastric distension in ferrets, intragastricpressure responses to, effects of partial truncal vagotomy, 1569

Vagotomy, relationship between gastric emptying of solid meal andgall bladder emptying before and after, 855

,truncal, and 1 year's ranitidine treatment effects on gastriccontents, 726-, -and parietal cell, effects on gastric acid and pancreatic

polypeptide responses to modified sham feeding, 280, partial, effects on intragastric pressure responses to

vagal stimulation and gastric distension in ferrets, 1569VALLA, D. See ROULOI, D, VALLA, D, et al.VALNES, K, BRANDTZAEG, P, ELGJO, K, STAVE, R, BAKI.tEN, K, and

FAUSA, O: Local immunoglobulin production is different ingastritis associated with dermatitis herpetiformis and simplegastritis, 1589

Valsalva's manoeuvre and hyoscinbutylbromide, effects on pressuregradient across wall of oesophageal varices, 1151

VALI7ONEN, V. See PUOLAKKAINEN, P, VALUFONEN, v, et al.VAN BERGE HENEGOUWEN, G P, VAN DER WERF, S D J, and RUBEN, A T:

Effect of long term lactulose ingestion on secondary bile saltmetabolism in man: potential protective effect of lactulose incolonic carcinogenesis, 675

VAN DER WERF, S D J. See VAN BERGE HENEGOUWEN, 0 P, VAN DER WERF,S Di, et al.

VAN DESSEL, MGi. See MCINERNEY, P D, VAN DESSEL, M G, et al.Variceal haemorrhage, comparison between trials invalidated by

variation in time of entry of subjects?, 653sclerotherapy (Leading article), 645

intravariceal and paravariceal techniques of, compara-tive trial, 657

Varices, oesophageal, pressure measurement in, new non-invasivemethod for, 1162

General index

,wall of, pressure gradient across, effect of Valsalva'smanoeuvre and hyoscinbutylbromide, 1151

Vascular and neuromuscular hamartoma of small intestine as formof Crohn's disease (Case reports), 1663

Vater's ampulla. See Ampulla of VaterVERDURON, J. See ROULOT, D, VALI A, D, et al.VERKASALO, M. See ARATO, A, SAVILAHTI, E, et al.VERNAY, M Y: Propionate absorption and metabolism in the rabbit

hindgut, 1077VERRI, A. See SCIARRETTA, G, FAGIOLI, (G, et al.VEYS, E. See CUVELIER, C, BARBATIS, C, et al.VIANELLO, F. See BATrAGLIA, G, DI MARIO, F, et al.VICINI, G. See SCIARRETTA, G, FAGIOLI, G, et al.vii, i c. See KUMAR, A, KUMAR, N, et al.VINAYAK, V K, SAXENA, A, and MALIK, A K: Alterations of humoral, cellmediated and antibody dependent cell mediated cytotoxicresponses during the course of amoebic infection in guinea pigs,1251

Visceral neuropathy, small intestinal motor responses to intra-luminal distension in patient with, 714

Vitamin B12 R-binder in human digestive tract, immunohisto-chemical localisation of, 339

VODERHOLZER, U. See LONDONG, V", LONDONG, v, et al.Von Recklinghausen's neurofibromatosis, achalasia-like disorder

of oesophagus in (Case report), 1522

WAGER, J. See MCNEIL, N 1, LING, K L E, et al.WAHREN, B. See BORCH, K, RENVALL, H, etal.WAKATSUKI, Y. See KUDO, H, INADA, M, et al.WALKER, E. See O'BRIEN, J D, THOMPSON, D G, et al.WALKER-SMITH, J A. See SANDERSON, I R, BOULTON, P, et al.WALLIN, L. See KRUSE-ANDERSEN, S, WALLIN, L, et al.WALSH, T N. See NOLAN, N P M, KELLY, C P, et al.WALT, R P, KEMP, R T, FILIPOWICZ, B, DAVIES, J G, BHASKAR, N K, andHAWKEY, c J: Gastric mucosal protection with selective inhibitionof thromboxane synthesis, 541

WALTERS, C L. See THOMAS, J M, MISIEWICZ, J J, et al.WALTERS, J. See BARDHAN, K D, THOMPSON, M, et al.WARHURST, G. See MORIARTY, K J, HIGGS, N B, et al.Water and electrolyte absorption, jejunal, from 2 enteral feeds,

importance of sodium content in, 681WATKINSON, G. See BIRNIE, G G, THOMPSON, G G, et al.WATSON, R G P, and LOVE, A H G: Intragastric bile acid concentrations

are unrelated to symptoms of flatulent dyspepsia in patients withand without gallbladder disease and postcholecystectomy, 131

WEBER, J N, THOM, S, BARRISON, I, UNWIN, R, FORSrER, S, JEFFRIES, D J,

BOYLSTON, A, and PINCHING, A J: Cytomegalovirus colitis andoesophageal ulceration in the context of AIDS: clinical manifesta-tions and preliminary report of treatment with Foscarnet(phosphonoformate) (Case report), 482

WEE, A. See KANG, J Y, WU, A Y 'i1, et al.WEIR, D G. See BARDHAN, K D, THOMPSON, M, etal.

See NOLAN, N P M, KELLY, C P, et al.WESTABY, D. See PATIL, D H, WESTABY, D, et al.WESTROM, B. See TAGESSON, C, TELEMO, E, et al.WETERMAN, I T. See BIEMOND, I, LANGE, G G DE, et al.WHEELER, J G. See BROWN, A M, BRADSHAW, M J, et al.WHELAN, G. See RUSSELL, C O H, and WHELAN, G

WHERRY, D C. See HARRISON, J, MORRIS, D L, et al.WHITFIELD, P F, and HOBSLEY, M: Comparison of maximal gastric

secretion in smokers and non-smokers with and without duodenalulcer, 557

WHORWELL, P J, PRIOR, A, and COLGAN, S M: Hypnotherapy in severeirritable bowel syndrome: further experience, 423

See also PRIOR, A, HARRIS, S R, et al.

1715

See also PRIOR, A, and WHORWELL, P JWICKS, A C B. See JENKINS, D, RICHARDS, J E, et al.WIENBECK, M. See KARAUS, M, SARNA, S K, etal.WIGGINS, H S. See STEPHEN, A M, WIGGINS, H S, et al.WILLIAMS, A: Effect of sulphasalazine and its metabolites on the

generation of reactive oxygen species (Letter), 912WILLIAMS, A J K, and BARRY, R E: Free radical generation by

neutrophils: a potential mechanism of cellular injury in acutealcoholic hepatitis, 1157

WILLIAMS, G T. See MACSWEEN, R N M, and WILLIAMS, G IWILLIAMS, J G. See DEAKIN, M, GLENNY, H P, etal.WILLIAMS, N S. See WOMACK, N R, WILLIAMS, N S, et al.WILLIAMS, P. See BJARNASON, 1, WILLIAMS, P, et al.WILLIAMS, R. See FORBES, A, PORTMANN, B, et al.

See GUARNER, F, HUGHES, R D, et al.See O'BRIEN, C J, WISE, RJ S, et al.

WILLIAMSON, R C N. See CHAVES, M, SMITH, M W, et al.See ROE, R, FERMOR, B, et al.

WILSON, J G. See BAGSHAW, P F, MUNS'I'ER, D J, et al.WILSON, 1 J G. See GOODLAD, R A, WILSON, r J G, et al.WINGATE, D L, and GILL, R C: GI disorders- the name's the thing

(Letter), 776See also GILL, R C, KELLOW, J E, et al.See also KELLOW, J E, GILL, R C, et al.

WISE, RJ S. See O'BRIEN, C J, WISE, RJ S, etal.WITZEL, L. See MERKI, H, WIIFZEL, L, et al.WOMACK, C. See HARRISON, J, MORRIS, D L, et al.WOMACK, N R, WILLIAMS, N S, HOLMFIELD, J H M, and MORRISON, J F B:

Pressure and prolapse- the cause of solitary rectal ulceration,1228

WONG, K K. See LAU, W Y, FAN, S 1, et al.WONG, K P. See LAU, W Y, FAN, S T, et al.WONG, S H. See LAU, W Y, FAN, SI', etal.WOOD, C B. See THOMPSON, J N, SALEM, R R, et al.WOODFORD, M. See MORIARTY, K J, HIGGS, N B, etal.WOODINGS, D F. See THOMAS, J M, MISIEWICZ, i J, etal.WORMSLEY, K G. See PENSTON, J, and WORMSLEY, K GWRIGHT, N A. See GOODLAD, R A, LEN'I'ON, W, et al.

See GOODLAD, R A, WILSON, IJ G, et al.WU, A Y T. See KANG, J Y, WU, A Y ', et al.WUST, B. See ZEITZ, M, HOPF, U, et al.WYKE, R J: Problems of bacterial infection in patients with liver

disease (Progress report), 623

YAMAGUCHI, S. See ONJI, M, KONDOH, H, et al.YAMAMOTO, M. See NISHIDA, T, MIWA, H, et al.YAMASHITA, Y. See OLSEN, P S, PEDERSEN, J H, et al.YANG, C S. See HSIEH, K H, SHU, S, et al.YIP, w c. See LAU, W Y, FAN, S 1, et al.YOKOYAMA, Y. See SAKAMOTO, K, HAGA, Y, et al.YOSHIMURA, R. See SAKAMOTO, K, HAGA, Y, et al.YOSHIOKA, A. See MIYACHI, Y, YOSHIOKA, A, et al.YVART, J. See BELAICHE, J, ZIIl-lOUN, J, et al.

ZAMBON, D. See ROS, E, and ZAMBON, D

ZEITZ, M, HOPF, U, WUST, B, GALANOS, C, MOLLER, B, LAWLEY, T J, andRIECKEN, E O: Absence of complement fixing antibodies againstlipopolysaccharides from Escherichia coli in a subgroup ofpatients with Crohn's disease, 1460

ZENTLER-MUNRO, P L: Cystic fibrosis - a gastroenterologicalcornucopia (Progress report), 1531

ZINSMEISTER, A R. See STONNINGTON, C M, PHILLIPS, S F, et al.ZIrTOUN, J. See BELAICHE, J, ZITTOUN, J, etal.ZUCKERMAN, A J. See ANDERSON, M G, HARRISON, T J, et al.

Abstracts IndexAbdominal. See Intra-abdominalAcetaldehyde adduct detection on hepatocyte membranes of rats

fed ethanol, A1393Acetate uptake in rat small intestine, not sodium dependent. A1335Acid injury, mucosal repair of rabbit duodenum after, role of

alkaline micro-environment in, A1406ACMI tumour probe and Atkinson tube for palliation of malignant

oesophageal strictures, comparison in 2 centres, A1380ADAMS, D H, et al.: Cellular chemotaxis to bile after liver transplanta-

tion, A1329Adenocarcinomas and adenomas, colonic, and normal colons, cell

kinetic parameters in, immunohistochemical analysis, A1368Adenylate cyclase, intestinal, different effects of VIP and PHI on,A1393

Adrenaline injection, endoscopic, for actively bleeding ulcers,controlled assessment, A1402

, submucosal, effect on blood loss from standard bleedingulcers, A1402

AFDHAL, N H, et al.: Controlled trial of clofazimine in Crohn'sdisease, A1391

, et al.: Effect of high and low protein meals on portalhaemodynamics in patients with cirrhosis and portal hyperten-sion, A1349

Africa, tropical, Campylobacterpyloridis in, A1409Age and sex dependence of enterochromaffin-like cell populations,A1410

AHMED, A, et al.: Eicosanoids in gastroduodenal mucosa of duo-denal ulcer patients treated with colloidal bismuth subcitrate,A1337

? et al.: Increased formation of leucotriene C4 in Campylobacterpyloridis-associated gastritis, A1405

AIDS. See HIV infectionAir and carbon dioxide insufflation, evaluation of discomfort aftercolonoscopy with, A1370

Albendazole therapy of hydatid disease, longterm clinical andexperimental results, A1385

Alcohol consumption, continued, effect on bleeding and mortalityafter variceal haemorrhage, A1386

misuse in patients with liver disease and controls, mitochon-drial aspartate aminotransferase as marker for, A1349-, pancreatitis induced by, social and surgical aspects of study,A371

ALDERSON, D, et al.: Isolation of purified human islets of Langerhansfor transplantation, A372

ALDRIDGE, M c, et al.: Colonic complications of severe acutepancreatitis, A371

Alkali infusion test in diagnosis of reflux gastritis, value of, andcomparison with 9Tc-HIDA test, A1408

Alkaline micro-environment, role in mucosal repair of rabbitduodenum after acid injury, A1406

ALLEN, P I M, et al.: Laser doppler assessment of human gastric bloodflow, A1403

Allergy. See Food pseudo allergyALLISON, M c, et al.: Colonic lymphocyte subpopulations in inflam-matory bowel disease, A1388

Allopurinol, effect on experimental pancreatitis, A368ALLUM, W H, et al.: C-myc oncogene product expression in benignand malignant gastric epithelia, A1404

AL-NAKIB, B, et al.: Experience with small bowel endoscopy inKuwait, A1369

ALVEYN, C G, et al.: Mitochondrial aspartate aminotransferase as a

marker for alcohol misuse in patients with liver disease andcontrols, A1349

Amino acids and peptides, orally administered, influence on proteinturnover kinetics in short bowel syndrome. A1397

5-Aminosalicylic acid and sulphasalazine, delayed-release, in treat-ment of mild to moderate ulcerative colitis relapse, A1329

, delayed-release, as maintenance treatment for ulcerativecolitis, comparison with sulphasalazine, A1390

Ampulla of Vater, carcinoma of, histopathology and staging of,A1400

proneness to other malignant tumours inpatients with, A370

Anal leukoplakia, A1368manometry, comparison of microtransducer, water and air

filled microballoon systems, A1361sphincter, internal, function in neurogenic faccal incontinence,

A1364, weak, rectal herniation through, rectal prolapse, anterior

mucosal prolapse, solitary rectal ulcer caused by?, A1363transitional zone, excision of, discrimination not impaired after

restorative proctocolectomy and ileo-anal anastomosis by, A1365ANDERSON, J R, and MORRAN, C G: Nd-YAG laser therapy in patients

with gastric and duodenal malignancies- an initial experience,A1374

ANDRE, C, et al.: Concomitant presence of IgE plasma cells induodenal and bronchial mucosae in asthmatic patients, A1398

? et al.: Effect of ritiometan on food pseudo allergy, A1352ANDREWS, H A, et al.: An audit of the management of Crohn's colitis,A1391

, et al.: Segmental colectomy for Crohn's disease of the colon,A1391

Angelchik antireflux prosthesis, dysphagia for solids as longtermeffect of, A1378

Angiodysplasia, colonic, gastrointestinal bleeding from othersources in, A1355

Anorectal disease, benign, endoluminal ultrasound in, A1369function in normal controls and irritable bowel syndrome

patients, effect of nicardipine, A1364-in ulcerative colitis, A1392manometry, results influenced by position of patient?, A1362physiology and videoproctography, outcome after rectopexy

for solitary rectal ulcer syndrome predicted by?, A1361sampling reflex, comparison of normal and incontinent sub-

jects, A1361sensation, role in continence mechanism, A1361sepsis, fistulac in, relevance of microbiology and necessity of

repeat examination under anaesthesia, A1369Antibiotics used for Campylobacter pyloridis, gastric secretion of,A1409

Antibodies against milk and circulating immune complexes ininflammatory bowel disease, A1387

Antimitochondrial antibody seropositivity and primary biliarycirrhosis, epidemiology of, in W. Scotland, A1346

Antiprotease therapy, intraperitoneal, pharmacokinetic study of,A367

Antiproteinase chemotherapy, intraperitoneal, specific, in acutenecrotising pancreatitis, experimental study, A367

Antral gastritis associated with duodenal ulcer, improvement byomeprazole, A1340

sucralfate v cimetidine for treatmentof, A1338

Antropyloroduodenal motor activity after intraduodenal acidinfusion, A1407

Antrum, 'acid', as possible cause of recurrent ulceration after highlyselective vagotomy, histological study, A1411

ARMSTRONG, D, et al.: Is continuous ambulatory monitoring ofduodenogastric reflux feasible?: in vitro assessment of an enzy-matic amperometric bile acid electrode, A1395

Arthritis, rheumatoid, role of wheat protein and gut abnormalitiesin, A1398

Asbestos as possible cause of gastric cancer, A1404Ascites, cirrhosis with, sympathetic activity increased in?, A1394

, hyponatraemic, oral urea in treatment of, A1386Asilone gel and Gaviscon liquid in treatment of reflux oesophagitis,comparison of, A1376

Aspartate aminotransferase, mitochondrial, as marker for alcoholmisuse in patients with liver disease and controls, A1349

Aspirin and bleeding peptic ulcer, A1401- ulceration induced by, prevention of, comparative study of

misoprostol and sucralfate in, A1338, what dose safe in gastric mucosal bleeding?, A1401

1716

Index to abstracts

Asthma, duodenal and bronchial mucosa in, concomitant presenceof IgE plasma cells in, A1398

Atkinson tube and ACMI tumour probe for palliation of malignantoesophageal strictures, comparison in 2 centres, A1380

Atrial natriuretic peptide, electrolyte transport in large intestineinfluenced by, A1396

Autoimmunity and HLA in chronic pancreatitis, A371

Bacterial. See MicrobialBacteriuria and primary biliary cirrhosis, no specific association'?,A1346

BALL, C s, et al.: Clinical applications of simultaneous 24 hourambulatory gastric and oesophageal pH monitoring, A1377

BALI.ANTYNE, K C, et al.: Detection of asymptomatic inflammatorybowel disease while screening for colorectal cancer, A1392

Balloons and bougies, oesophageal stricture dilatation with, radialpressures during, A1370

BAMBA, T, et al.: Difluoromethyl-ornithine inhibits adaptive ilealmucosal hyperplasia after pancreaticobiliary diversion in the rat,A1394

BARBARA, L, et al.: Omeprazole 20 mg om and ranitidine 150 mg bd inthe healing of benign gastric ulcers - an Italian multicentre study,A1341

BARDHAN K D, et al.: Value of omeprazole in the management oferosive oesophagitis refractory to high dose cimetidine, A1375

BARR, H, et al.: Laser therapy or intubation for palliation ofmalignant dysphagia, A1358

, et at.: Photodynamic therapy for colorectal cancer, A1368Barrett's oesophagus, malignancy in, risk factors for, A1379

malignant change in, early detection of, value of endo-scopic surveillance in, A1379

BARRISON, I C, et al.: Diagnostic yield of upper gastrointestinalendoscopy in human immunodeficiency virus antibody positivepatients, A1369

BARTON, R, et al.: Incidence, morbidity and mortality of Crohn'sdisease in Scottish children, A1356

BASSO, D, et al.: Serum markers and clinical data in diagnosingpancreatic cancer: a contrastive approach, A370

BA'FMAN, P A, et al.: Jejunal mucosal architecture in HIV infectedmale homosexuals, A1399

BA'I'I', R M, et al.: Application of organ culture to the investigation oflectin-induced damage to the brush border membrane, A1397

BENJAMIN, I S, et al.: Cytological diagnosis of hepatobiliary andpancreatic malignancy, A1401

Benzodiazepines, stimulation of duodenal epithelial bicarbonatesecretion, A1333

Beta-adrenoreceptors in modulation of upper gastrointestinaltransit and carbohydrate absorption, A1396

Bicarbonate secretion, gastric, in man, increased by esaprazole,A1337

,in vitro and in man, effect of bismuth subcitrate,A1342

-in duodenal epithelium, stimulation by benzodiazepines,A1333

Bile, cellular chemotaxis to, after liver transplantation, A1329duct calculi extraction after endoscopic sphincterotomy, active

policy for, A1360common, calculi in, endoscopic prosthesis for, A1371

,- sphincterotomy for, in patientswith gall bladder in situ unfit for surgery, A1371

large (>2 cm), associated with recurrentpyogenic cholangitis, endoscopic management of, A1371

methyl tert-butyl ether for, dissolutionwithout radiological disappearance after, A1385

surgery and/or endoscopic sphinctero-tomy for, multivariate analysis of risk factors in, A1383

diameter after cholecystectomy, assessment by pre- andpost-operative ERC, A1384

Biliary aetiology in acute pancreatitis, early diagnosis of, A370

-cirrhosis, primary, and antimitochondrial antibody sero-positivity, epidemiology of, in W. Scotland, A1346-, -, and bacteriuria, no specific association?, A1346

,and normal liver, sulphation and desulphation in,A1345-, -, IgG3 in, raised serum concentrations and increased

synthesis by peripheral blood lymphocytes, A1347-, , pre- and post-liver transplantation, circulating

osteocalcin as index of bone turnover in, A1345lipid and gall stone dissolution responses to combined cheno-

deoxycholic acid and ursodeoxycholic acid treatment, A1360pain, acalculous, computer history analysis in, A1383

, sphincter of Oddi motility in, A1384-pancreatitis, acute, role of early ERCP and sphincterotomy in,A1384

BINNIE, N R, et al.: Action of cisapride on intractable constipationassociated with spinal and pelvic nerve injury, A1363

-,et al.: Stimulation of anterior sacral nerve roots in man: theproximal extent and differential effects on colonic motility, A1363

BIRD, P, et al.: IgG3 in PBC: raised serum concentrations andincreased synthesis by peripheral blood lymphocytes, A1347

BISHOP, A E, et al.: Endocrine tumours in ARG-vasopressin/simianvirus 40 large T antigen transgenic mice: a model for humanmultiple endocrine neoplasia type I syndrome?, A1393

, et al.: Enterochromaffin like cell populations are dependent onage and sex, A1410

Bismuth subcitrate, colloidal. See De-NolBISSET, w M, etal.: Ontogeny of small intestinal motor activity, A1355BLAIR, S D, et al.: Early blood transfusion promotes recurrent

gastrointestinal haemorrhage, A1402Bleeding duodenal ulcer, isolated duodenal tamponade in treatment

of, A1373peptic ulcer and aspirin, A1401- , comparison of Nd YAG laser, heater probe and no

endoscopic therapy for, A1342, intragastric fibrinolysis in, A1402

-time, useful test in cirrhosis?, A1348ulcers, active, endoscopic adrenaline injection for, controlled

assessment, A1402-, standard, blood loss from, effect of submucosal adrena-

line, A1402Blood flow, cerebral, increased, in fulminant hepatic failure,management of, A1330-, gastric, laser doppler assessment of, A1403loss from standard bleeding ulcers, effect of submucosal

adrenaline, A1402,portal and peripheral, short chain fatty acid concentrations

after caecal lactulose installation at surgery, A1355-transfusion, early, recurrent gastrointestinal haemorrhage pro-moted by, A1402

BMY-25368-01, intravenous, and ranitidine, effect on meal stimu-lated gastric acid secretion in man, A1339

BOL'UON, R P, et al.: Thyroid function as a prognostic indicator incirrhosis, A1386

Bombesin and meal stimulation of pancreatic enzyme secretion, roleof cholecystokinin in, studied with CR 1409, A1381

? effect on serum trypsin after various forms of gastric surgery,A1381

Bone turnover in primary biliary cirrhosis pre- and post-livertransplantation, circulating osteocalcin as index of, A1345

BONNIERE, P, et al.: Prospective randomised trial of endoscopicsclerotherapy and transhepatic embolisation in patients withsevere cirrhosis and acute variceal bleeding: preliminary results,A1348

BOOTH, I w, et al.: Characterisation of defective sodium coupledglucose transport in congenital glucose-galactose malabsorptionusing jejunal brush border membrane vesicles, A1397

BOUGHUFON-SMITH, N K, and WHITT1LE, B J R: Inhibition of ethanolinduced leucotriene synthesis and damage in the rat gastricmucosa by BW755C, A1334

1717

Index to abstracts

Bougies and balloons, oesophageal stricture dilatation with, radialpressures during, A1370

Bowel. See Intestine(s)BOYD, E J s, et al.: What really happens during maintenance therapy

of duodenal ulcer?, A1341BRAVERMAN, D z: Gall bladder contraction in patients with irritablebowel syndrome, A1384

Bread made from coarse flour digested more slowly and incom-

pletely, A1352Breath hydrogen, fasting, in coeliac disease, A1353

monitoring in Pneumatosis coli, A1366tests, H2- or 14C-, in diagnosis of small intestinal bacterial

overgrowth, A1353British Society of Gastroenterology: Jubilee Meeting, A1328British/Belgian Gallstone Study Group postdissolution trial, A1359Bronchial mucosa and duodenal mucosa in asthma, concomitant

presence of IgE plasma cells in, A1398BROOK, M G, et at.: Histological improvement after antivirail treat-ment for chronic hepatitis B virus infection, A1387

BROWN, G A, et al.: Faccal chymotrypsin accurately predicts exocrinepancreatic function in infants and children, A1400

BROWN, N j, et al.: Effect of ileal infusion of fats, detergents and bileacids on stomach to caecum transit time in the rat, A1355

Brush border membrane, ileal, lectin-induced damage to, investiga-tion with organ culture, A1397

vcsicles, jejunal, characterisation of defectivcsodium coupled transport in congenital glucose-galactose mal-absorption using, A1396

, osmotically active, preparation from biopsysamples of human small intestine, A1333

BURKE, D A, and AXON, A R: Adhesion of colitic E coli to isolatedhuman colonocytes, A1328

,et al.: Faecal short chain fatty acids in ulcerative colitis andcontrols, A1387

,et al.: Oral tobramycin improves the outcome of acuteulcerative colitis, A1390

BURKE, P i., et al.: Transthoracic colon interposition for benignoesophageal stricture, A1378

BURT, A D, et al.: Distribution of calcitonin gene related peptide andsubstance P-containing nerves in liver: an immunohistochemicalstudy, A1330

BW755C inhibition of ethanol induced leucotriene synthesis anddamage in rat gastric mucosa, A1334

CA-50 in differential diagnosis of benign and malignant diseases ofthe stomach and ocsophagus, A1405

Caecum, lactulose installation at surgery, portal and peripheralblood short chain fatty acid concentrations after, A1355

CAIRNS, S R, and COrrON, P B: Potential for endoscopic therapy in

primary sclerosing cholangitis, A 1342Calcitonin gene related peptide and substance P, nerves containing,

distribution in liver, immunohistochemical study, A1330Calculi, bile duct, extraction after endoscopic sphincterotomy,

active policy for, A1360in common bile duct, endoscopic prosthesis for, A1371

- , sphinctcrotomy for, in patients withgall bladder in situ unfit for surgery, A1371

large (>2 cm), associated with recurrentpyogenic cholangitis, endoscopic management of, A1371

methyl tert-butyl ether for, dissolutionwithout radiological disappearance after, A1385

surgery and/or endoscopic sphinctero-tomy for, multivariate analysis of risk factors in, A1383

Cainpylobacter pyloridis, antibiotics used for, gastric secretion of,A 1409

detection in gastric and duodenal biopsies, sensitivity andspecificity of 4-hour rapid urease test to culture and histology for,A1406

cffect of colloidal bismuth subcitrate in non-ulcer dys-pepsia, A1337

of vagotomy, A1410-,eradication of, and duodenal ulcer healing, efficacy of

colloidal bismuth subcitrate in different dosage regimes in, A1409gastric mucosa colonised with, itn vitro mucus glyco-

protein synthesis and secretion by, A1409gastritis associated with, increased leucotriene C4 forma-

tion in, A1405in children associated with, A1357

in tropical Africa, A1409prospective study by bacteriology, histology, urease test

and serology (ELISA and immunoblotting), A1408Carbohydrate absorption and upper gastrointestinal transit, modu-

lation by beta-adrenoreceptors, A1396meals, hepatic venous pressure gradient increased by, in

cirrhotics after bleeding from oesophageal varices, A1348Carbon dioxide and air insufflation, evaluation of discomfort after

colonoscopy with, A1370Carcinoid syndrome, survival in, effect of hepatic artery embolisa-

tion, A1329Carcinoma, colorectal, and desmosomes, A1368

patients at risk of developing local recurrenec predictedby intraoperative pelvic cytology, A1368

photodynamic therapy for, A1368screening for, analysis of 132 tumours, A1344

-,gastric, adjuvant tamoxifen in treatment of, controlled study,A1404

and colorcctal, gastrin in, iti itro and iti vivo studies,A1332

asbestos as possible cause of, A1404mucus glycoprotein biosynthesis changes at tumour site

in, A1332risk of, and priority for endoscopy, determination from

analysis of dyspeptic symptoms, A1405,oesophageal, intra-abdominal metastases for, detection of,

laparoscopy, ultrasound or CT for'?, A1378survival in, factors influencing, A1358

of ampulla of Vater, histopathology and staging of, A1400proneness to other malignant tumours in

patients with, A370, pancreatic, diagnosis of, serum markers and clinical data in,

A370e, nzyme linked lectin assay compared with RIA CA19-9

as serum test for, A1401, glycoprotein markcr for, new, carbohydrate sequencing

of, A1394-,-rlrelated to, new, identification in serum by electro-

phoresis and Iectin blotting, A372, intcrstitial hyperthermia for treatment of, experimental

studies, A1382, lectin histochemistry in, A369

CARR, N D, et al.: Evaluation of the nutritional effects and surgicalrisks during a two year study after gastroplasty for morbid obesity,A1351

CASE, w c: Effects of cisapride upon responses of the oesophagus todistension, A1377

Cerebral blood flow, increalsed, in fulminant hepatic failure,management of, A1330

CESAR, M, et al.: Prognostic criteria in acute pancreatitis: a criticalevaluation, A368

CHADWICK, v s, et al.: Mucosal cell receptors and enteric nerves

mediate the spasmogenic effects of bacterial N-formyl oligopep-tides on guinea pig ileum, A 1336

Chenodeoxycholic acid and ursodeoxycholic acid, combined treat-ment with, bile lipid and gall stone dissolution responses to,A1360

CHESLYN-CURIIS, s, et al.: Diagnosis of occult intra-abdominal sepsiswith "'Indium labelled leucocyte scanning early versus latescanning, A1403

CIIESNER, I M, et al.: Colonoscopic management of malignant polyps- an audit, A1367

1718

Index to abstracts

,et al.: A non-isotopic test for pancreatic insufficiency whichdistinguishes small bowel malabsorption, A1382

CHING, C K, and RHODES, J M: Carbohydrate sequencing of a new

pancreatic cancer glycoprotein marker, A1394Identification of a new pancreatic cancer-related glyco-

protein in serum by celctrophoresis and lectin hlotting, A372A novel enzyme linked lectin assay compared with RIA

CA 19-9 as a serum test for pancreatic cancer, A1401-, et al.: Lectin histochemistry in pancreatic carcinoma, A369CHISHOLM, E M, et al.: Analysis of dyspeptic symptoms to determine

risk of gastric cancer and priority for endoscopy, A1405Chloride and sodium transport mechanisms and effects of short

chain fatty acids in human infant colon, A1366Cholangiocarcinoma, inoperable, endoscopic management using

Iridium-192, A1400Cholangiography (Cholangiopancreatography), retrograde, endo-

scopic. See ERC (ERCP)Cholangitis, acute, with acute pancreatitis, outcome in, A369

, pyogenic, recurrent, large (>2 cm) common bile duct stonesassociated with, endoscopic management of, A1371

, sclerosing, primary, endoscopic therapy in, potential for,A1342

natural history of, and HLA antigens as predictorsof prognosis, A1345

portal tract lymphocyte populations in, A1330suppurative, acute, urgent endoscopic drainage in, A1384

Cholecystectomy, bile duct diameter after, assessment by pre- andpost-operative ERC, A1384

Cholecystokinin, plasma, secretion of, and gall bladder contraction,stimulation by coffee ingestion, A1383

, role in stimulation of pancreatic enzyme secretion by bomb-esin and meal, studied with CR 1409, A1381

Choledocholitholysis in vivo using methyl tertiary butyl ether,A1360

CHUNG, S c s, et al.: Bile duct diameter after cholecystectomy:assessment by pre- and post-operative ERC, A1384-, et al.: The effect of submucosal adrenaline on blood loss from

standard bleeding ulcers, A1402Chymotrypsin, faecal, in prediction of exocrine pancreatic function

in infants and children, A1400Cimetidine, high dose, erosive oesophagitis refractory to, value of

omeprazole in management of, A1375v sucralfate for treatment of duodenal ulcer associated antral

gastritis, A1338Cirrhosis and portal hypertension, portal haemodynamics in, effect

of high and low protein meals, A 1349biliary. See Biliary cirrhosisbleeding time useful test in?, A1348hepatic venous pressure gradient increased by carbohydrate

meals after bleeding from oesophageal varices in, A1348, reduced vascular tone in, caused by 'desensitisation' to sym-

pathetic nervous activity?, A1349, severe, and acute variceal bleeding, endoscopic sclerotherapy

and transhepatic embolisation in patients with, trial of, A1348, thyroid function as prognostic indicator in, A1386with ascites, sympathetic activity increased in?, A1394

Cisapride, action on intractable constipation associated with spinaland pelvic nerve injury, A1363

and gastrooesophageal reflux in children with and withoutneurological disorders, A1376

, effects on oesophageal responses to distension, A1377improvement of oesophageal transit in patients with dysphagia,

results of trial, A1377CLARKE, G s, et al.: Cisapride and gastrooesophageal reflux in

children with or without neurological disorders, A1376Clofazimine in Crohn's disease, trial of, A1391C-myc oncogene product expression in benign and malignant gastric

epithelia, A1404Coeliac disease and inflammatory bowel disease, lung permeability

in, A1336

fasting breath hydrogcn in, A1353lactulose/mannitol as screening test for, A1332microvillus membranes in, electrophoretic analysis of,

A1335non-responsive, small bowel enema appearance specific

to, A1352relatives of dermatitis herpetiformis patients with,

immunofluorescent and genetic studies, A1352sorbitol malabsorption in, A1353

sprue, rectal gluten challenge in, sequence of immunopatho-logical events after, A1392

Coffee ingestion, stimulation of plasma cholecystokinin secretionand gall bladder contraction by, A1383

COGHLAN, J G, et al.: Efficacy of different dosage regimes in duodenalulcer healing and eradication of Camnpylobacterpylori, A1409

Colectomy for severe idiopathic constipation, assessment of,A1343

, segmental, for Crohn's disease of colon, A1391Colic, genesis of, studies on, A1372Colitis, severe, enteral nutrition in, A1328

, ulcerative, acute, outcome improved by oril tobramycin,A1390

anorectal function in, A 1392E coli from patients with, adhesion to isolated human

colonocytes, A1328faccal short chain fatty acids in, A1387inhibition of fatty acid oxidation as cause of, A1387,maintenance treatment for, comparison of delayed-

release 5-aminosalicylic acid and sulphasalazine as, A1390relapse in, mild to moderate, delayed-release 5-

aminosalicylic acid and sulphasalazine in treatment of, A1329segmental colonic transit in, effect of Asian v Caucasian

diet, A1366Collagen quantification in chronic pancreatitis, A372Colon, adenocarcinomas and adenomas of, and normal colons, cell

kinetic parameters in, immunohistochemical analysis, A1368and rectum, biopsies, histopathological assessment of,

observer variation in, A1389angiodysplasia, gastrointestinal bleeding from other sources

in, A1355-, cellular proliferation rates in normal subjects, effect of faccal

stream, A1366Crohn's disease of, management of, audit of, A 1391

segmental colectomy for, A1391dynamic scanning for definition of regional defect in severe

idiopathic constipation, A1365, human infant, sodium and chloride transport mechanisms and

effects of short chain fatty acids in, A1366interposition, transthoracic, for benign oesophageal stricture,

A1378l,ymphocyte subpopulations in inflammatory bowel disease,

A1388, motility, proximal extent and differential effects of ainterior

sacral nerve root stimulation, A1363mucosa of, amphibian, restitution in vitro, A1395neoplasia of, suspected, open access colonoscopy as single

investigation for, A1371pI, effect of dietary fibre supplementation in healthy volun-

teers, A1366rat, electrogenic ion trainsport, effects of starvation and

rcfeeding, model for famine diarrhoea'?, A1395sodium and potassium transport, differential effects of pure

mineralocorticoid and glucocorticoid hormones, A1335transport, electrogenic, segmental variability of, A1335

transit, segmental, in ulcerative colitis, effect of Asian v

Caucasian diet, A1366Colonic complications of severe acute pancreatitis, A371

See also IntracolonicColonocytes, human, isolated, adhesion of colitic E coli to, A1328Colonoscopic management of malignant polyps, audit of, A1367

1719

Index to abstracts

Colonoscopy, evaluation of discomfort with carbon dioxide and airinsufflation after, A1370

, left sided, as screening procedure for colorectal neoplasia inasymptomatic volunteers -45 years, A1367

, neoplastic lesions detected at, diagnosis of, histology andcytology compared for, A1343

, open access, as single investigation for suspected colonicneoplasia, A1371

Colorectal carcinoma and desmosomes, A1368-and gastric carcinoma, gastrin in, in vitro and in vivo

studies, A1332-, patients at risk of developing local recurrence predicted

by intraoperative pelvic cytology, A1368photodynamic therapy for, A1368screening for, analysis of 132 tumours, A1344

neoplasia, left sided colonoscopy as screening procedure inasymptomatic volunteers >45 years for, A1367

Complement, activated, cytotoxic to isolated rat hepatocytes, A1394Computed tomography scanning, serial, in acute pancreatitis, A369Computer history analysis in acalculous biliary pain, A1383Constipation, chronic, idiopathic, longstanding, surgical managc-ment of, physiological parameter to dictate, A1362

idiopathic, severe, colectomy for, assessment of, A1343dynamic colonic scanning for definition of regional

defect in, A1365intractable, associated with spinal and pelvic nerve injury,

action of cisapride on, A1363severe, histopathological study, A1364

, lateral puborectalis division for, experience of, A1364Continence mechanism, role of anorectal sensation in, A1361Copper and metallothionein in liver disease with copper retention,

histopathological study, A1348CORAZZA, G R, et al.: Fasting breath hydrogen in coeliac disease,A1353

,et al.: Sorbitol malabsorption in normal volunteers and in

patients with coeliac disease, A1353CORBErr, M E, et al.: Measurement of pepsin synthesis in man using

I-` C-leucine, A1331CORDER, A P, et al.: Acute septic complications of diverticular

disease: a radical approach improves survival, A1343CORTOT, A (French Cooperative Study): Omeprazole versus raniti-

dine in duodenal ulcer patients unhealed after six weeks' treat-ment with H2-receptor antagonists, A1341

COUPE, M, et al.: Effect of hepatic artery embolisation on survival incarcinoid syndrome, A1329

COURTNEY, M G, et al.: An assay for folate catabolism - implicationsfor the RDA, A1350

Cow's milk sensitive enteropathy contributing to failure to thrive incystic fibrosis in childhood, A1356

COX, J G C, et al.: Radial pressures during stricture dilatation withbougies and balloons, A1370

COXON, J E, and BECKLY, D E: Gastric vascular ectasia: nine cases andtreatment by laser photocoagulation, A1370

CR 1409 studies of role of cholecystokinin in stimulation ofpancreatic enzyme secretion by bombesin and meal, A1381

CRABTREE, J E, et al.: In vitro mucus glycoprotein synthesis andsecretion by gastric mucosa colonised with Campylobacterpyloridis, A1409

CRAMA-BOHBOUTH, G E, et al.: Are clinical activity indices helpful inassessing active intestinal inflammation in Crohn's disease?,A1389

CREUTZFELDT, w, et al.: Serum gastrin concentrations and gastricendocrine cell population during longterm treatment withomeprazole in man, A1341

CROFTS, T j, et al.: Prospective randomised controlled trial ofconservative therapy versus surgery for perforated duodenalulcer, A1375

Crohn's disease, active intestinal inflammation in, assessmcnt of,clinical activity indices helpful?, A1389

-,clofazimine in, trial of, A1391

enterovaginal fistulae in, A1392,established, combination antimycobacterial chemo-

therapy with major clinical response in, A1390, faecal diversion for, sustained epithelial proliferation

after, objective evidencc of mucosal recovery from, A1391in management of, A1344

granulomata of, macrophage and lymphocyte subpopula-tions in, A1388

in Scottish children, incidence, morbidity and mortality,A1356-,microbial isolates in, identification with cloned DNA

probes, A1328,mucosal glycoprotein synthetase as protective mecha-

nism in, A1388-of colon, management of, audit of, A1391

segmental colectomy for, A1391,postoperative fistulae in, causes and prevention of, A1329,smoking and sugar intake in, separate but interactive risk

factors, A1389-, strictureplasty for, 9-year experience, A1329

CROWE, j, et al.: A study of intracolonic hydrogen and methaneconcentrations in patients, A1370

CUNNINGHAM, K M, and READ, N W: Incorporating lipid into soup or

main course has different effects on gastric emptying and nutrientabsorption, A1350

CUSCHIERI, A: Long term experience of pancreatic resection using a

banding technique, A368Cysteine and penicillamine inhibition of acetaldehyde induced

superoxide production by neutrophils, A1331Cystic fibrosis in childhood, failure to thrive in, cow's milk sensitive

enteropathy contributing to, A1356,intensive dietary counselling in adolescents with, A1352jejunal biopsies from children with, absence of secretory

response in, A1356

DAMMANN, H G, et al.: Effect of intravenous BMY-25368-0l andranitidine on meal stimulated gastric acid secretion in man, A1339

DANESH, B J z, et al.: Ability of duodenum to maintain a neutral pHmicroclimate in response to acid challenge in endoscopicallynormal and duodenal ulcer subjects, A1405

,et al.: Does the pH influence the protective action of sucralfateagainst mucosal injury?, A1338

DAVIDSON, B R, et al.: Endoscopic sphincterotomy for common bileduct calculi in patients with gall bladder in situ considered unfit forsurgery, A1371

DAWES, R F H, and ROYLE, G T: Postoperative pain relief withdiclofenac suppositories, A1397

DEAKIN, M, and WILLIAMS, i G: Reproducibility of 24-hour studies ofintragastric acidity, nocturnal volume, acid and pepsin secretionby the aspiration method, A1407

Defecation, continued, in presence of loop ileostomy, aetiology of,A1365

,disordered, accompanied by primary personality disorder?,A1373

, physiology of, and importance of levator ani muscles, A1362Defecographic findings in young healthy volunteers, A1361DEFIZE, j, et al.: N-methyl-N'-nitro-N-nitrosoguanidine induces

changes in rat and human pepsinogen phenotypes, A1332DEHN, T C B, et al.: Strictureplasty for Crohn's disease - a nine year

experience, A1329De-Nol, duodenal ulcer patients treated with, eicosanoids in

gastroduodenal mucosa of, A1337,effect on gastric bicarbonate secretion in vitro and in man,

A1342-, efficacy of different dosage regimes in duodenal ulccr healing

and eradication of Campylobacterpyloridis, A1409in non-ulcer dyspepsia, trial of, and effect on Campylobacter

pyloridis, A1337Dermatitis herpetiformis patients, coeliac relatives of, immuno-

fluorescent and genetic studies, A1352

1720

Index to abstracts

Desmosomes and colorectal cancer, A1368DEUS, 1, et al.: Early diagnosis of biliary aetiology in acute

pancreatitis, A370DHIR, N K, et al.: Changes in mucus glycoprotein biosynthesis at thetumour site in gastric cancer, A1332

Diabetes mellitus and idiopathic faecal incontinence, comparisonfor sensorimotor pelvic floor neuropathy, A1363

Diarrhoea of famine, effects of starvation and refeeding on electro-genic ion transport in rat colon as model for, A1395-, postvagotomy, impaired adaptive relaxation in patients with,A1403

, protracted, idiopathic, and circulating enterocyte antibodies,jejunal HLA D/DR Ag expression in children with, A1355

related to fat malabsorption and partial villous atrophy in HIVinfection in male homosexuals, A1353

DIAS, L M, et al.: Endoscopic prosthesis for common bile duct stones,A1371

Diclofenac suppositories, postoperative pain relief with, A1397Diet, 6(X) calorie, Garren gastric bubble with and without, effect on

weight loss and gastric emptying, trial of, A1412Dietary counselling, intensive, in adolescents with cystic fibrosis,A1352

Difluoromethyl-ornithine inhibition of adaptive ileal mucosal hyper-plasia after pancreaticobiliary diversion in rat, A1394

Disaccharidase deficiencies, diagnosis of, endoscopic biopsies for,A1398

DISIDA, 99m-Tc, scanning, quantitative, in sphincter of Oddidysfunction, A1381

Diverticular disease, acute septic complications of, survivalimproved by radical approach in, A1343

, complicated, national audit of, A1343DNA in rat hepatocytes, synergistic effect of hepatotropin and

insulin, A1393probes, cloned, in identification of Crohn's disease microbial

isolates, A1328DOBLE, A, and SIM, A J w: Endoluminal ultrasound in benign

anorectal disease, A1369DONALDSON, D R, et al.: Anal leukoplakia, A1368DOO EY, J s, et al.: Methyl tert-butyl ether for common duct stones:

dissolution without radiological disappearance, A1385DOUGLAS, B R, et al.: Ingestion of coffee stimulates plasma chole-

cystokinin secretion and gall bladder contraction in man,A1383

Drug metabolism, alteration in elderly, fall in liver volume, bloodflow and perfusion in aging man as explanation for, A1347

DUA, K S, et al.: Is highly selective vagotomy a good operation forduodenal ulcer?: a longer look at the answer, A1374

Dumping syndrome, SMS 201-995 in, effect on packed cell volume,blood glucose and plasma GI peptides, A1396

Duodenal acidification and gastrin responses after feeding, patho-physiological implications, A1410

and gastric subnuclear vacuolated mucous cells, A1408See also Intraduodenal

Duodenogastric reflux. See Reflux, duodenogastricDuodenum, ability to maintain neutral pH microclimate in response

to acid challenge in endoscopically normal and duodenal ulcersubjects, A1405-, biopsies, and gastric biopsies, detection of Campylobacter

pyloridis in, sensitivity and specificity of 4-hour rapid urease testto culture and histology for, A1406-, epithelial bicarbonate secretion, stimulation by benzodia-

zepines, A1333, guinea pig, villous uptake of iron and enterocyte iron binding

proteins in, developmental changes in, A1333,mucosa of, and bronchial mucosa in asthma, concomitant

presence of IgE plasma cells in, A1398, pH, and gastric pH, postprandial, in exocrine pancreatic

insufficiency, effect of omeprazole, A1340rabbit, mucosal repair after acid injury, rolc of alkaline micro-

environment in, A1406

, ulcer, antral gastritis associated with, improvement byomeprazole, A1340

sucralfate v cimetidine for treat-ment of, A1338-, , basal and stimulated plasma gastrin in, correlation with

failure of H2 receptor antagonists and recurrent ulceration afterhighly selective vagotomy, A1374

l,beeding, isolated duodenal tamponade in treatment of,A1373

childhood, pathophysiology of, A1357cicosanoids in gastroduodenal mucosa of patients

treated with colloidal bismuth subcitrate, A1337healing, and eradication of Cainpylobacter pyloridis,

efficacy of colloidal bismuth subcitrate in different dosage regimesin, A1409

impairment by food, A1407Maalox TC tablets and ranitidine in, comparative

multicentre study, A1337highly seiective vagotomy for, long term assessment of

efficacy, A1374,maintenance therapy for, recurrence and other factors

during, A1341,-,mucosal gastrin and gastric acid secretion affected by

smoking in, A1374, ,omeprazole v ranitidine for, with weekly endoscopic

assessment, A1340, perforated, conservative therapy v surgery for, trial of,

A1375recurrence during maintenance treatment, A1375T cell populations and activity in, effect of famotidine

treatment, A1338- ,-, unhealed after 6 weeks' treatment with H2-receptor

antagonists, omeprazole v ranitidine in, A1341DUROUX, P, et al.: Optimising the effect of nizatidine on gastric pH:

early evening meal together with the drug is best, A1339Dyspepsia, non-ulcer, colloidal bismuth subcitrate in, trial of, and

effect on Campylobacter pyloridis, A1337Dyspeptic symptoms, analysis of, determination of risk of gastriccancer and priority for endoscopy from, A1405

Dysphagia for solids as longterm effect of Angelchik antirefluxprosthesis, A1378

malignant, palliation of, laser therapy or intubation for, A 1358,oesophageal transit in patients with, improvement by cisa-

pride, results of trial, A1377

EDE, R j, et al.: Endoscopic management of inoperable cholangio-carcinoma using Iridium-192, A1400

, et al.: Management of increased cerebral blood flow in patientswith fulminant hepatic failure, A1330FTcm-EHIDA/external imaging for non-invasive assessment of duo-denogastric reflux, validation of, A1408

Eicosanoids in gastroduodenal mucosa of duodenal ulcer patientstreated with colloidal bismuth subcitrate, A1337

Elderly, altered drug metabolism in, fall in liver volume, blood flowand perfusion in aging man as explanation for, A1347

Electrocoagulation, multipolar, in treatment of ulcers with non-

bleeding visible vessels, trial of, A1342Electrolyte transport in large intestine influenced by atrial natriu-

retic peptide, A1396ELLFNBOGEN, s, el al.: Evidence for a gastro-cholecystic reflex for gall

bladder emptying in man, A1411, et al.: Interdigestive gall bladder emptying and its relationship

to motor activity in man, A1359ELMES, M E, et al.: Metallothionein and copper in liver disease withcopper retention: a histopathological study, A1348

Endocrine tumours in ARG-vasopressin/simian virus 4t) large Tantigen transgenic mice, model for human multiple endocrineneoplasia type I syndrome?, A1393

Endoscopic adrenaline injection for actively bleeding ulcers, con-

trolled assessment, A1402

1721

Index to abstracts

, submucosal, effect on blood loss from standard bleedingulcers, A1402

biopsies for diagnosis of disaccharidase deficiencies, A1398drainage, urgent, in acute suppurative cholangitis, A1384management of inoperable cholangiocarcinoma using Iridium-

192, A1400-of large (>2 cm) common bile duct stones associated with

recurrent pyogenic cholangitis, A1371-prosthesis for common bile duct stones, A1371

retrograde cholangiography (cholangiopancreatography). SeeERC(ERCP)

sclerotherapy and transhepatic embolisation in patients withsevere cirrhosis and acute variceal bleeding, trial of, A1348

-sphincterotomy for common bile duct calculi in patients withgall bladder in situ unfit for surgery, A1371

, stone extraction after, active policy for, A1360surveillance in early detection of malignant change in Barrett's

oesophagus, value of, A1379therapy in primary selerosing cholangitis, potential for, A1342ultrasound of pancreatic disorders, A1382

Endoscopy, gastrointestinal, upper, diagnostic yield in HIV anti-body positive patients, A1369

paediatric, experience of 531 cases, A1370-,small bowel, experience in Kuwait with, A1369Enprostil in treatment of gastric ulcer, A1336Enteral nutrition in severe colitis, A1328Enterochromaffin-like cell populations, dependence on age and sex,

A1410Enterohepatic circulation patterns over 24 hours, A1385Enteropathy, cow's milk sensitive, contributing to failure to thrive in

cystic fibrosis in childhood, A1356, induction by activated T cells in human small intestine, A1334

Enterovaginal fistulae in Crohn's disease, A1392Enzyme linked lectin assay as serum test for pancreatic cancer,

comparison with RIA CA19-9, A1401ERC, pre- and post-operative, in assessment of bile duct diameter

after cholecystectomy, A1384ERCP, early, and sphincterotomy, role in acute biliary pancreatitis,A1384

ERIKSEN, C A, et al.: Cisapride improves oesophageal transit inpatients with dysphagia: results of a randomised double-blindcrossover trial, A1377

, et al.: Duodenal acidification and gastrin responses afterfeeding: a new look at the pathophysiology, A1410

,et al.: Manometric interpretation of the oesophageal egg

transit test: a useful test for oesophageal motility disorders, A1358Esaprazole, gastric bicarbonate secretion in man increased by,A1337

Escherichia coli, colitic, adhesion to isolated human colonocytes,A1328

Ethanol, hepatocyte membranes of rats fed, detection of acetalde-hyde adducts on, A1393

, leucotriene synthesis and damage in rat gastric mucosa

induced by, BW755C inhibition of, A1334EVANS, D F, et al.: Non-invasive measurement of gastric emptying

using applied potential tomography, A1410

Faecal chymotrypsin in prediction of exocrine pancreatic function ininfants and children, A1400

diversion for Crohn's disease, sustained epithelial proliferationafter, objective evidence of mucosal recovery from, A1391-in management of Crohn's disease, A1344incontinence. See Incontinence, faccalshort chain fatty acids in ulcerative colitis patients and controls,

A1387stream, effect on colonic cellular proliferation rates in normal

subjects, A1366Famine diarrhoea, effects of starvation and refeeding on electro-

genic ion transport in rat colon as model for, A1395

Famotidine 40 mg nocte, 24 hour intragastric acidity and plasmagastrin concentration in healthy volunteers taking, A1339

treatment, effect on T cell populations and activity in duodenalulcer, A1338

Fat as luminal stimulus for gastric somatostatin release, A1331malabsorption and partial villous atrophy, diarrhoea related to,

in HIV infection in male homosexuals, A1353Fatty acids, oxidation, inhibition of, as cause of ulcerative colitis,A1387

, polyunsaturated, ingestion of, and peptic ulcer, evidencefor direct relationship, A 1411

,short chain, effects on sodium and chloride transportmechanisms in human infant colon, A1366

faccal, in ulcerative colitis patients and con-

trols, A1387portal and peripheral blood concentrations

after caccal lactulose installation at surgery, A1355FEIL, w, et al.: Mucosal repair of rabbit duodenum: role of an

alkaline micro-environment, A1406Fibre, dietary, inhibition of starch absorption by, A1354

,supplementation with, effect on colonic pH in healthyvolunteers, A1366

Fibresigmoidoscopy, open access, comparative audit of efficacy,A1372

Fibrinolysis, intragastric, in bleeding peptic ulcer disease, A1402FINLAY, I G, et at.: Can videoproctography and anorectal physiology

predict outcome after rectopexy for the solitary rectal ulcersyndrome?, A1361

, et al.: Physiology of defecation - the importance of the levatorani muscles, A1362

Fish oil, use in inflammatory bowel disease, A1391FISHER, S E, et al.: Do patients with disordered defecation have a

primary personality disorder?, A1373Fistulae, enterovaginal, in Crohn's disease, A1392

in anorectal sepsis, relevance of microbiology and necessity ofrepeat examination under anaesthesia, A1369

, postoperative, in Crohn's disease, causes and prevention of,A1329

FLOREANI, A, et al.: No specific association between primary biliarycirrhosis and bacteriuria?, A1346

Fluid secretion induced by 5-hydroxytryptamine in human jejunum,prostaglandin E2 mediation of, A1396

Folate catabolism, assay for, implications for recommended dietaryallowance, A1350

FOLEY, D P, et at.: Left sided colonoscopy as screening procedure forcolorectal neoplasia in asymptomatic volunteers c45 years, A1367

Food, duodenal acidification and gastrin responses after, patho-physiological implications, A1410

, impairment of duodenal ulcer healing by, A1407-pseudo allergy, effect of ritiometan, A1352FORBES, A, et al.: Autoimmunity and HLA in chronic pancreatitis,A371

,et al.: Nutritional support in fulminant hepatic failure: thesafety of lipid solutions, A1347

N-Formyl oligopeptides, bacterial, spasmogenic effects on guineapig ileum mediated by mucosal cell receptors and enteric nerves,

A1336FRENCH COOPERAIIVE STUDY: Omeprazole versus ranitidine induodenal ulcer patients unhealed after six wecks' treatment withH2-receptor antagonists, A1341

Fructose and sorbitol malabsorption in functional bowel disease,A 1372

FULLAR'I'ON, G M, et al.: Effect of simulated upper gastrointestinalhaemorrhage on gastric acid secretion and GI hormones, A1401

,et al.: Quantitative 99m-Tc DISIDA scanning in sphincter ofOddi dysfunction, A1381

Gall bladder contraction and plasma cholecystokinin secretion,stimulation by coffee ingestion, A1383

in irritable bowel syndrome, A1384

1722

Index to abstracts

-emptying, gastro-cholecystic reflex in man for, evidencefor, A1411

,interdigestive, and relationship to motor activity,A1359

motility in presence of gall stones, A1360-motor function in gall stone patients, integrated study,

A1395stone dissolution and bile lipid responses to combined cheno-

deoxycholic acid and ursodeoxycholic acid treatment, A1360- pancreatitis, sex differences in, A1383stones, gall bladder motility in presence of, A1360

- motor function in patients with, integratedstudy, A1395

, radiolucent, calcification of, postulated mechanism of,and ursodeoxycholate treatment, A1385

,recurrence after dissolution (British/Belgian GallstoneStudy Group trial), A1359

Gastrectomy, partial, with Billroth-I1 and Roux-en-Y anastomosis,effect on serum pepsinogens, prospective study, A1403

Gastric acid regulation of postprandial somatostatin release in man,A1331

secretion and gastrointestinal hormones, effect of simu-lated upper gastrointestinal haemorrhage, A1401

and mucosal gastrin in duodenal ulcer affected bysmoking, A1374

, meal stimulated, in man, effect of intravenousBMY-25368-01 and ranitidine, A1339

adaptive relaxation, impairment in patients with postvagotomydiarrhoea, A1403

in gastro-oesophageal reflux, A1376and duodenal pH, postprandial, in exocrine pancreatic

insufficiency, effect of omeprazole, A1340subnuclear vacuolated mucous cells, A1408

bicarbonate secretion in man increased by esaprazole, A1337-in vitro and in man, effect of bismuth subcitrate,

A1342biopsies and duodenal biopsies, detection of Campylobacter

pyloridis in, sensitivity and specificity of 4-hour rapid urease testto culture and histology for, A1406

-blood flow, laser doppler assessment of, A1403bubble, Garren, with or without 600 calorie diet, effect on

weight loss and gastric emptying, trial of, A1412carcinoma, adjuvant tamoxifen in treatment of, controlled

study, A1404and colorectal carcinoma, gastrin in, in vitro and in vivo

studies, A1332asbestos as possible cause of, A1404mucus glycoprotein biosynthesis changes at tumour site

in, A1332, risk of, and priority for endoscopy, determination from

analysis of dyspeptic symptoms, A1405emptying and nutrient absorption, different effects of lipid

incorporated into soup or main course, A1350, biphasic pattern after truncal vagotomy and pyloroplasty,

mechanisms governing, A1332-, non-invasive measurement using applied potential tomo-

graphy, A1410-of liquids, effect of meal temperature, A1407-of solids delayed by smoking, A1406

-endocrine cell population and serum gastrin concentrationsduring longterm omeprazole treatment, A1341

epithelia, benign and malignant, C-myc oncogene productexpression in, A1404

-mucosa colonised with Campylobacter pyloridis, in vitro mucusglycoprotein synthesis and secretion by, A1409-, rat, ethanol induced leucotriene synthesis and damage in,

BW755C inhibition of, A1334-mucosal bleeding, what dose of aspirin safe in?, A1401

pH and oesophageal pH monitoring, ambulatory, 24 hour,simultaneous, clinical applications of, A1377

, effect of nizatidine optimised by early evening meal withdrug, A1339

secretion of antibiotics used for Cainpylobacter pyloridis,A1409

somatostatin release, fat as luminal stimulus for, A1331surgery, serum trypsin after various forms of, effect of

bombesin, A1381ulcer, benign, healing of, omeprazole 2t) mg om and ranitidine

150 mg bd in, Italian multicentre study, A1341.omeprazole and ranitidine in treatment of, inter-

national multicentre study, A1340-, enprostil in treatment of, A1336

-vagotomy, proximal, clinical results 10 years aftcr, A1404-vascular ectasia, 9 cases and treatment by laser photocoagula-

tion, A1370See also Intragastric; Stomach

Gastrin and duodenal acidification responses after feeding, patho-physiological implications, A1410

in gastric and colorectal cancer, in vitro and in vivo studies,A1332

, mucosal, and gastric acid secretion in duodenal ulcer affectedby smoking, A1374

,plasma levels, and intragastric acidity, 24 hour, in healthyvolunteers taking famotidine 40 mg nocte, A1339

basal and stimulated, in duodenal ulcer, correlationwith failure of H2 receptor antagonists and recurrent ulcerationafter highly selective vagotomy, A1374-, serum concentrations, and gastric endocrine cell population

during longterm omeprazole treatment, A1341Gastritis, antral, associated with duodenal ulcer, improvement by

omeprazole, A1340sucralfate v cimetidine for treat-

ment of, A1338associated with Campylobacter pyloridis in children, A1357

increased leucotriene C4 formation in,A1405

, reflux, diagnosis of, value of alkali infusion test in, andcomparison with 9Tc-HIDA test, A1408

Gastro-cholecystic reflex for gall bladder emptying in man, evidencefor, A1411

Gastroduodenal malignancies, Nd-YAG laser therapy in, A1374-mucosa of duodenal ulcer patients treated with colloidal

bismuth subcitrate, eicosanoids in, A1337'mucus-bicarbonate' barrier, effect of indomethacin, A1411

Gastroenteritis, postacute, need to regrade?, A1351Gastrointestinal abnormalities and wheat protein, role in rheuma-

toid arthritis, A1398endoscopy, upper, diagnostic yield in HIV antibody positive

patients, A1369, paediatric, experience of 531 cases, A1370

haemorrhage from other sources in colonic angiodysplasia,A1355

, lower, role of in vivo 99"Tc-labelled red blood cell scinti-graphy in, A1367

recurrent, promoted by early blood transfusion, A1402upper, simulated, effect on gastric acid secretion and GI

hormones, A1401tract, human and guinea pig, VIP binding sites in, localisation

using in vitro autoradiography, A1333-transit time in rat, effect of ileal infusion of fats, detergents and

bile acids, A1355-, upper, and carbohydrate absorption, modulation by

beta-adrenoreceptors, A1396See also Mouth-to-caecum transit

Gastro-oesophageal reflux. See Reflux, gastro-oesophagealGastroplasty for morbid obesity, evaluation of nutritional effectsand surgical risks during 2 year study after, A1351

Gaviscon liquid and Asilone gel in treatment of reflux oesophagitis,comparison of, A1376

GEMAYEL, N, et al.: A prospective, controlled trial of the Garren

1723

Index to abstracts

gastric bubble with or without 6(X) caloric diet on weight loss andgastric emptying, A1412

Giardia lamblia, human serum IgA response to, A1351GILLEN, P, et al.: Barrett's oesophagus: risk factors for malignancy,A1379

Globus sensation, manometric findings in patients with, A1378Glucose-galactose malabsorption, congenital, defective sodium

coupled glucose transport in, characterisation using jejunal brushborder membrane vesicles, A1396

Glutathione S-transferase levels in autoimmune chronic activehepatitis, A1349

Gluten challenge, rectal, in coeliac sprue, sequence of immuno-pathological events after, A1392

Glycochenodeoxycholic acid and glycocholic acid, jejunal infusionof, inhibition of small bowel motility and transit by, A1399

c,ileal infusion of, in feedback regulation of jejunal andileal transit and motility, A1398

Glycoprotein marker for pancreatic cancer, carbohydrate sequenc-ing of, A1394

,mucus, synthesis and secretion in vitro by gastric mucosa

colonised with Campylobacter pyloridis, A1409, new, related to pancreatic cancer, identification in serum by

electrophoresis and lectin blotting, A372Glycoprotein synthetase, mucosal, as protective mechanism in

Crohn's disease, A1388Glycoproteins, mucus, biosynthesis of, changes at tumour site in

gastric cancer, A13326OKA, A K j, et al.: Human serum IgA response to Giardia lainblia,A1351

GOODMAN, A j, et al.: Therapeutic fresh frozen plasma in acutepancreatitis: intravenous or intraperitoneal?, A1382

GOUDIE, B M, et al.: Epidemiology of antimitochondrial antibodyseropositivity and primary biliary cirrhosis in the west of Scotland,A1346

GOULBOURNE, I A, et al.: Risk of death from acute pancreatitis, A370GRANTI, H w, et al.: Polyunsaturated fatty acid ingestion and peptic

ulcer- evidence for a direct relationship, A1411Granulomata of Crohn's disease, macrophage and lymphocyte

subpopulations in, A1388GUSLANDI, M: Esaprazole increases gastric alkaline secretion in man,A1337

Gut. See Gastrointestinal tractGUYAN, P M, et al.: Oxygen free radicals do not activate the zymogens

of human pancreatic proteases, A1394

Haem arginate therapy for acute hepatic porphyria, A1347Haemorrhage, gastric mucosal, what dose of aspirin safe in?, A1401

gastrointestinal. See Gastrointestinal haemorrhagevariceal. See Variceal haemorrhageSee also Bleeding

Haemorrhagic necrosis, massive, of liver after liver transplantation,A1344

HALt, C, et al.: Intraoperative peivic cytology accurately predictsthose at risk of developing local recurrence of colorectal cancer,A1368

HAMBER6, o, et al.: Inhibition of starch absorption by dietary fibre,A1354

HANSL.IP, J et al.: Effects of 'mucosal protective' and antisecretorydrugs on assimilation of food bound vitamin B12, A1341

HARRISON, J D, et al.: A randomised, controlled study of adjuvantTamoxifen in the treatment of gastric carcinoma, A1404

HAR-I1LEY, M N, and MACKIE, C R: Impaired gastric adaptive relaxationin patients with postvagotomy diarrhoea, A1403

,et al.: Gastric adaptive relaxation in patients with gastro-oesophageal reflux, A1376.

HAYES, P c, and WILLIAMS, R: Oral urea in the treatment ofhyponatraemic ascites, A1386

et al.: Glutathione S-transferase levels in autoimmune chronicactive hepatitis, A1349

HEAGERIY, A H M, etal.: Tc-99m-HMPAO labelled white cell imaging- a new tcchnique for the dynamic assessment of inflammatorybowel disease, A1389

HEALY, M, et al.: Phosphatidylcholine degradation in small intestinalbacterial overgrowth, A1397

HEATION, N D, et al.: A histopathological study of severe constipation,A1364

HENDERSON, j, et al.: Ursodeoxycholate treatment aind postulatedmechanism of calcification of previously radiolucent gall stones,A1385

Hepatic artery embolisation, effect on survival in carcinoid syn-

drome, A1329porphyria, acute, haem arginate therapy for, A1347venous pressure gradient increased by carbohydrate meals in

cirrhotics after bleeding from oesophageal varices, A1348-. See also Intrahepatic; LiverHepatitis B virus infection, chronic, antiviral treatment for, histo-

logical improvement after, A1387chronic active, autoimmune, glutathione S-transferase levels

in, A1349,persistent measles virus infection due to

defective measles virus antigen expression in, A1346Hepatobiliary and pancreatic malignancy, cytological diagnosis of,A1401

Hepatocellular and obstructive jaundice, effect on triglyceridemetabolism, A1349

Hepatocyte membranes of rats fed ethanol, detection of acetalde-hyde adducts on, A1393

Hepatocytes, isolated, transplantation of, morphological changes inpancreas, suggesting endocrine regeneration, induced by, A1400

,rat, DNA in, synergistic effect of hepatotropin and insulin,A 1393

isolated, activated complement cytotoxic to, A1394Hernia, hiatal, influence on oesophageal function, A1377HETZEL, D j, et al.: Healing and relapse of reflux oesophagitis aftcr

treatment with omeprazole 20) mg or 40 mg daily, A1376Hexamethyl propylene amine oxime. See HMPAOHEYEN, F, et al.: Causes and prevention of postoperative fistulae in

Crohn's disease, A1329, et al.: Enterovaginal fistulae in Crohn's disease, A1392

HEYLINGS, J R, et al.: Benzodiazepines stimulate duodenal epithelialbicarbonate secretion, A1333

Hiatal hernia, influence on oesophageal function, A1377HILL, s M, et al.: Cow's milk sensitive enteropathy: an important

cause of failure to thrive in cystic fibrosis in childhood, A1356Histamine H,-receptor. See H2-receptorHIV antibody positive patients, upper gastrointestinal endoscopy

in, diagnostic yield of, A1369infection, diarrhoea related to fat malabsorption and partial

villous atrophy in male homosexuals with, A1353,jejunal mucosal architecture in male homosexuals with,

A1399HLA and autoimmunity in chronic pancreatitis, A371

antigens as predictors of prognosis in primary sclerosingcholangitis, A1345D/DR Ag expression in jejunum of children with idiopathic

protracted diarrhoea and circulating enterocyte antibodies, A1355HOLLINGSWORTH, J A, et al.: Gastric secretion of antibiotics used for

Camnpylobacter pyloridis, A1409Homosexuals, male, HIV infected, jejunal mucosal architecture in,A1399

infection in, diarrhoea related to fat malabsorptionand partial villous atrophy in, A1353

HOOD, K, et al.: Bile lipid and gall stone dissolution responses tocombined chenodeoxycholic acid and ursodeoxycholic acid treat-ment, A1360

, et al.: The British/Belgian Gallstone Study Group's postdisso-lution trial, A1359

HOSKING, s w, et al.: Can metoclopramide arrest active bleedingfrom varices?: a prospective controlled trial, A1380

1724

Index to abstracts

HOUGHiON, P w J, et al.: Asbcstos: a possiblc aictiological caIusc ofgastric cancer?, A1404

""'Tc-IIMPAO, Icucocytcs labcllcd with, in diaignosis and aisscss-mcnt of inflammatory bowcl discasc, A 1328, A1389

Il.-rcccptor antaigonists in ocsophaigitis, rcsponsc prcdictcd byphysiological studies?, A 1358

pl1 response to, effcct of smoking. A1406See also WY-45,727

HiUBSCHER, S (;, et al.: Massivc hacnmorrhagic nccrosis of thc livcraiftcr livcr transplantation, A1344

HtJI, w M, et al.: Omcpraizolc improvcs antral gaistritis associated withduodenal ulccr, A1340

,et al.: Omcprazolc ranitidinc for duodenal ulccr - wccklycndoscopic assessment, A1340

et al.: Smoking affects mucosal gakstrin and gastric acid

sccrction in duodenal ulccr, A1374,et al.: Sucralfate v cimctidinc for the trca.tmcnt of duodcnal

ulccr associated antral gastritis, A1338tiUNIrER, J o, et al.: A doublc blind raindomiscd multicentrc studycomparing Maalox TC tablcts and ranitidinc in the healing ofduodcnal ulcer, A1337

Ilydattid diseasc, albcndazolc thcrapy for, longtcrm clinical andcxpcrimcntal rcsults, A1385

,combination chcmothcrapy in, A 1346Hlydrogcn and mcthanc, intracolonic conccntrations in paticnts,A1370

in breath, fasting lcvcls. in cocliaic disca.sc. A 1353-, monitoring of, in Pncumatosis coli, A1366

5-Hydroxytryptaminc, fluid sccrction in humain jcjunum induccdby, prostaglandin E2 mcdiation of, A 1396

llypcrtcnsion, portal, aind cirrhosis, portail hatemodynamics in,cffcct of high aind low protcin mcals, A 1349

tiypcrthcrmia, intcrstitial, as ncw therapy for intrahcpatic nco-

plasms, A1350,for trcatmcnt of pancreatic cainccr, cxpcrimcntal

studics, A1382Ilyponatracmic ascitcs, oral urca. in trcatmcnt of, A 1386

ICS 2(05-9301 rcduction of mouth-to-caccuim transit timc in man,A1373

llco-anal anastomosis and proctocolectomy. rcstorativc, discrimina-tion not impaired by cxcision of anal transitional zonc after, A1365

lleostomy, loop, continucd 'dcfccation' in prcscncc of, actiology of,At1365

Ileum and jejunum, transit and motility, fccdbaick rcgulaition by ilcalinfusion of glycochcnodcoxycholic acid, A1398

brush bordcr mcmbrane, lcctin-induccd damnagc to, invcstiga-tion with organ culturc, A 1397

,guinca pig, spasmogcnic cffccts of bactcriail N-formyl oligo-pcptidcs mcdiatcd by mucosal ccil rcccptors aind cntcric ncrvcs,A1336

, infusion of fats, detergents and bile acids, cffcct on stomach tocaecum transit time in rat, A1355

, mucosal hyperplasia, adaptive, aftcr pancrcaticobiliary divcr-sion in rat, inhibition by difluoromethyl-ornithinc. A1394

Immune complexes, circulating, and milk antibodies in inflamma-tory bowel disease, A1387

Immunoglobulin A in human serumii, rcsponse to Giardia laminbia,A 1351

E plasma cells, concomitant presencc in duodenail and bron-chial mucosa in asthma, A1398G3 in primary biliary cirrhosis. raised serum concentrations

and increased synthesis by peripheral blood lymphocytes, A1347Incontinence, faccal, idiopathic, and diabetes mcilitus, comparison

for sensorimotor pelvic floor neuropathy, A 1363, postanal repair for, clinical aind physiological

evaluation of. A1362, neurogenic, internal anal sphincter function in, A1364ncuropathic, primary, combincd sensorimotor deficit in,

A 1363

lndium Icucocvtc scanning in diaignosis of occult intra-abdominalscpsis, carly v Ialtc scanning in. A1403

Indomcthacin aind ranitidinc, cffcct on gaistric acidity. A 1373cffcct oni gaistrodtiodenait 'mucus-bicarbonatc' ba.rricr, A1411

Insulin and hcpatotropin. syncrgistic cffcct on DNA in rat hcpaito-cvtcs, A1393

Intcstinall aidcnvylatc. differcnt cffects of VIP aind Pill on, A 1393ischacmia. acutc. dil'tercntial rcsponsc of gut nctiropcptidcs in,

A1334- obstruction. currcnt spcctrum of, A1372

pscudo-obstruction. ilmanomctry helpful'?, A1354Intcstinc, ltrgc, clcctrolytc transport. influicnccd by aitriati natri-

uLrctic pcptidc. A 1396smnill, bactcrial ovcrgrowth. diagnosis of, fI- or `4C-brcath

tcsts in, A 1353phosphatidylcholinc dcgradation in, A 1397tcsts for, comparativc valuc of, A1351

cndoscopy ot, cxpcricncc in Kuwait with, A1369,cncnia appcarancc spccific to non-rcsponsivc cocliac

discasc, A 1352humain, biopsy samplcs of. prcpiaraition of osmoticailly

activc bruish bordcr mcmbrarnc vcsicics from. A1333cntcropaithy induccd by activatcd T cclls in, A1334

.matabsorption a ind pancrcatic insufficicncy, non-

isotopic tcst (l'AS/PABA cxcrction ratio) diffcrcntiating. A1382.motility aind transit, nhbibition bv glycochcnodcoxy-

cholic aind glycocholic acids inftiscd in jcjunum, A1399m-.otor aictivity, ontogcny of, A1355

rat, acctatc uptaikc, not sodium dependent, A1335transplants, succcssful, in rat, dcnervation primc catusc

of rcduccd watcr absorption in, A1335-,-, transport function, cffccts of vitamin E dcficicncy,A1354

Intcstincs, fluid aibsorption, laxativc action of phcnolphthalcin on,mcchanism of, A 1336-, functionall discasc, fructosc and sorbitol malabsorption in,A1372

disordcrs, allicd, diagnosis with monoclonal antibodicsand clcctron microscopy, A1373

infant mousc, watcr transport in rdro, cffcct of rotavirusinfcction. A 1334

-,inflammaition of, active, in Crohn's discasc, asscssment of,clinicial aictivity indiccs hclpful?, A1389

inflammatory discasc, and cocliac discase, lung pcrmcabilityin, A1336

symptomatic. detcction during scrccning forcolorcctal caniccr, A1392

colonic lymphocytc subpopulaitions in, A 1388,diagnosis and asscssmcnt with Tc 99m IIMPAO

labcllcd lcucocytcs, A1328, A1389milk aintibodics and circulating immunc complcxcs

in, A1387pcrsonality primairy or sccondary to chronic illncss

in'?, A1388usc of fish oil in, A1391

irritatblc bowcl syndromc, abnormal vagal function in, A1344- _,.anorcctal function in, cffcct of nicardipinc,

A1364gall bladdcr contraction in. A1384sigmoid colon in. incrcascd scgmcntail aictivity

and intraluminail prcssurcs in, rccordcd with ncw manomctrictechniquc, A 1344

-,microvillus mcmbrancs, in cocliac discasc, cIcctrophorcticanalysis of, A 1335

,short bowcl syndromc, protein turnovcr kinetics in, influcnccof orally aidministcrcd amino atcids ;ind pcptidcs, A1397

Intra-abdominal mctastascs for ocsophagcal canccr, dctcction of,laparoscopy. ultrasound or CT for'?, A1378- scpsis, occult, diagnosis with Indium labcllcd lcucocytc

scanning, ciarly v latc scanning in, A1403

1725

Index to abstracts

Intracolonic hydrogen and methane concentrations in patients,A1370

Intraduodenal acid infusion, antropyloroduodenal motor activityafter, A1407

Intragastric acidity and plasma gastrin concentration, 24 hour, inhealthy volunteers taking famotidine 40 mg nocte, A1339

, nocturnal, effect of indomethacin and ranitidine, A1373volume, acid and pepsin secretion, 24-hour studies

by aspiration method, reproducibility of, A1407, 24 hour, dose dependent inhibition by WY-45,727, A1339

fibrinolysis in bleeding peptic ulcer disease, A1402pH response to H2-receptor antagonists, effect of smoking,

A1406Intrahepatic neoplasms, interstitial hyperthermia as new therapy

for, A1350IQBAL, s, et al.: Sulphation and desulphation in normal human liverand primary biliary cirrhosis, A1345

Iridium-192, endoscopic management of inoperable cholangiocar-cinoma using, A1400

Iron, villous uptake, and enterocyte iron binding proteins in guineapig duodenum, developmental changes in, A1333

ISABEL-MARTINEZ, L, et al.: Effect of obstructive and hepatocellularjaundice on triglyceride metabolism, A1349

Islets of Langerhans, human, purified, isolation for transportation,A372

JAFFE, v, et al.: Morphological changes in the pancreas, suggestive ofendocrine regeneration, induced by transplantation of isolatedhepatocytes, A1400

JANSEN, J B M j, et al.: Prospective study of the effect of partialgastrectomy with Billroth-I1 and Roux-en-Y anastomosis on

serum pepsinogens, A1403JASS, J R, et al.: Juvenile polyposis- a precancerous condition, A1367Jaundice, obstructive and hepatocellular, effect on triglyceride

metabolism, A1349Jejunum and ileum, transit and motility, feedback regulation by ileal

infusion of glycochenodeoxycholic acid, A1398-, biopsies from children with cystic fibrosis, absence of secretory

response in, A1356, brush border membrane vesicles, characterisation of defective

sodium coupled glucose transport in congenital glucose-galactosemalabsorption using, A1396

, glycochenodeoxycholic and glycocholic acid infusions in,inhibition of small bowel motility and transit by, A1399,HLA D/DR Ag expression in children with idiopathic pro-

tracted diarrhoea and circulating enterocyte antibodies, A1355-, human, fluid secretion induced by 5-hydroxytryptamine,

prostaglandin E2 mediation of, A1396-, mucosal architecture in HIV infected male homosexuals,A1399

JENKINS, H R, et al.: Mechanisms of transport of sodium and chlorideand the effects of short chain fatty acids in the human infant colon,A1366

JENKINS, S A, et al.: Effects of SMS 201-995 on reticuloendothelialsystem activity in rats with acute pancreatitis, A1381

JENKINSON, L R, et al.: Expression of normal ranges in 24 hour intra-oesophageal pH monitoring, A1378

-,et al.: Influence of hiatal hernia on oesophageal function,A1377

JOHNSTON, B J, et al.: The effect of vagotomy on Campylobacterpyloridis, A1410

JOHNSTON, D A, and WORMSLEY, K G: Food is bad for ulcers, A1407JOHNSTON, P, et al.: Immunohistochemical analysis of cell kinetic

parameters in colonic adenocarcinomas, adenomas, and normalcolons, A1368

JONG, A J L DE, et al.: Studies using the CCK-receptor antagonist CR1409 point to an important role for cholecystokinin in thestimulation of pancreatic enzyme secretion by bombesin and ameal, A1381

JUBY, L D, et al.: Lactulose/mannitol: an ideal screening test forcoeliac disease?, A1332

KALRA, L, et al.: Open access fibresigmoidoscopy: a comparativeaudit of efficacy, A1372

KAMM, M A, et al.: Dynamic colonic scanning - defining the regionaldefect in severe idiopathic constipation, A1365

-,et al.: Experience of lateral puborectalis division for severeconstipation, A1364

, et al.: Is colectomy for severe idiopathic constipation asuccess?, A1343

KATSCHINSKI, B, et al.: Smoking and sugar intake are separate butinteractive risk factors in Crohn's disease, A1389

-,et al.: Variations in the incidence and spatial distribution ofpatients with primary acute pancreatitis in the Nottinghamdefined population (1969-85), A371

KEAIING, i j, et al.: Effects of prednisolone, sulphasalazine, 5-aminosalicylic acid and indomethacin on prostaglandin E2 andleucotriene B4 production, A1390

KEIGHLEY, M R B, and WINSLET, Mc: Discrimination is not impaired byexcision of the anal transitional zone after restorative proctocolec-tomy and ileo-anal anastomosis, A1365

KELLY, D A, et al.: Do we need to regrade postacute gastroenteritis?,A1351

,et al.: Skeletal myopathy secondary to selenium deficiency,A1354

KELLY, S B, et al.: Use of CA-50 in the differential diagnosis of benignand malignant diseases of the stomach and oesophagus, A1405

KENNEDY, R H, and SARLES, H: Collagen quantification in chronicpancreatitis, A372

KERRIGAN, D D, et al.: Human antropyloroduodenal motor activityafter intraduodenal acid infusion, A1407

KLINKENBERG-KNOL, E c, et al.: Longterm treatment with omeprazolein resistant refluxoesophagitis: effects on endoscopic healing andfasting serum gastrin levels, A1379

KREUNING, j, et al.: Effect of bombesin on serum trypsin after variousforms of gastric surgery, A1381

KUMAR, D, et al.: Intestinal pseudo-obstruction: is manometryhelpful?, A1354

Lactulose, caecal installation at surgery, portal and peripheral bloodshort chain fatty acid concentrations after, A1355

Lactulose/mannitol as screening test for coeliac disease, A1332LAFERLA, G A, et al.: In vivo choledocholitholysis using methyl

tertiary butyl ether, A1360LAINE, L: Multipolar electrocoagulation in the treatment of ulcers

with non-bleeding visible vessels: a prospective, controlled trial,A1342

LAMERS, C B H w, et al.: Value of the alkali infusion test in thediagnosis of reflux gastritis, A1408

Langerhans, islets of, human, purified, isolation for transportation,A372

LANZA, F, et al.: A single blind comparative study of misoprostol tosucralfate and placebo in the prevention of aspirin inducedulceration, A1338

LANZON-MILLER, s, et al.: 24 hour intragastric acidity and plasmagastrin concentration in healthy volunteers taking famotidine 4t)mg nocte, A1339

LARVIN, M, and MCMAHON, M J: Illness scoring systems- improvedprecision for monitoring the progress of acute pancreatitis'?,A1382

Serial objective measurement of severity in acute pan-creatitis, A369

,et al.: Pharmacokinetic study of intraperitoneal antiproteasetherapy, A367

Laser doppler assessment of gastric blood flow, A1403photocoagulation, Nd-YAG, in treatment of gastric vascular

ectasia, A1370therapy, Nd-YAG, in gastric and duodenal malignancies,

A1374

1726

Index to abstracts

or intubation for palliation of malignant dysphagia, A1358Lectin assay, enzyme linked. See Enzyme linked lectin assay

histochemistry in pancreatic carcinoma, A369Lectins, damage to brush border membrane induced by, investiga-

tion with organ culture, A1397LEESE, T, et al.: Fresh frozen plasma in the treatment of acute

pancreatitis- a multicentre prospective clinical trial, A367Leucocytes, "'Indium-labelled, scanning with, in diagnosis of occult

intra-abdominal sepsis, early v late scanning in, A1403,Tc 99m HMPAO labelled, in diagnosis and assessment of

inflammatory bowel disease, A1328, A1389Leucotriene B4 and prostaglandin E2 production, effects of

prednisolone, sulphasalazine, 5-aminosalicylic acid and indo-methacin, A1390

C4, increased formation in Campylobacterpyloridis-associatedgastritis, A1405

synthesis and damage in rat gastric mucosa induced by ethanol,BW755C inhibition of, A1334

Leukoplakia, anal, A1368LEUNG, J W c, et al.: Endoscopic management of large (>2 cm) CBD

stone associated with recurrent pyogenic cholangitis, A1371-, et al.: Randomised controlled assessment of endoscopic

adrenaline injection for actively bleeding ulcers, A1402et al.: Role of early ERCP and sphincterotomy in acute biliary

pancreatitis, A1384, et al.: Urgent endoscopic drainage in acute suppurative

cholangitis, A1384Levator ani muscles, importance in defecation, A1362LINEHAN, I P, and RUSSELL, R C G: Design of a pancreatic surgery

database, A372: Follow up of accessory sphincteroplasty for chronic

pancreatitis associated with pancreas divisum, A368LINSELL, J c, et al.: Manometric findings in patients with the globus

sensation, A1378Lipid incorporation into soup or main course, different effects on

gastric emptying and nutrient absorption, A1350solutions for nutritional support in fulminant hepatic failure,

safety of, A1347Lipids, biliary, and gall stone dissolution, responses to combined

chenodeoxycholic acid and ursodeoxycholic acid treatment,A1360

Liver cell(s). See Hepatocyte(s)disease, alcohol misuse in, mitochondrial aspartate amino-

transferase as marker for, A1349with copper retention, metallothionein and copper in,

histopathological study, A1348, distribution of calcitonin gene related peptide- and substance

P-containing nerves in, immunohistochemical study, A1330failure, fulminant, increased cerebral blood flow in, manage-

ment of, A1330-, -, nutritional support in, safety of lipid solutions for,

A1347metastases, development of, changes in hepatic haemo-

dynamics with, A1330, growth and development of, effect of SMS 201-995,

A1350, normal, and primary biliary cirrhosis, sulphation and desul-

phation in, A1345transplantation, cellular chemotaxis to bile after, A1329

for fulminant hepatic failure, A1345massive haemorrhagic necrosis of liver after, A1344primary biliary cirrhosis before and after, circulating

osteocalcin as index of bone turnover in, A1345volume, blood flow and perfusion, fall in aging man as

explanation for altered drug metabolism in elderly, A1347LODGE, J P A, et al.: Surgical management of bleeding oesophageal

varices: Warren shunt versus lienorenal shunt- 15 years' experi-

ence, A1386LOFr, D E, et al.: Coeliac sprue: the sequence of immunopathological

events after rectal gluten challenge, A1392

, et al.: Comparative value of tests for small intestinal bacterialovergrowth, A1351

LONDON, N J M, et al.: Serial computed tomography scanning in acutepancreatitis, A369

LUCEY, M R, et al.: Fat is a luminal stimulus for gastric somatostatinrelease, A1331-, et al.: Gastric acid regulates postprandial somatostatin release

in man, A1331LUNDELL, L, et al.: Omeprazole or ranitidine in the treatment of

reflux oesophagitis- result from a double blind, randomised,Scandinavian multicentre study, A1375

Lung permeability in inflammatory bowel disease and coeliacdisease, A1336

Lymphocyte populations in portal tract in primary sclerosingcholangitis, A1330

Lymphocytes and macrophages, subpopulations in granulomata ofCrohn's disease, A1388

colonic, subpopulations in inflammatory bowel disease, A1388See also T cell(s)

Maalox TC tablets and ranitidine in healing of duodenal ulcer,comparative multicentre study, A1337

MCCOl.L, K E L, et al.: Haem arginate therapy for acute hepaticporphyria, A1347

MCCORMACK, P A, et al.: Carbohydrate meals increase hepatic venous

pressure gradient in cirrhotics who have bled from oesophagealvarices, A1348

MCCORMICK, P A, et al.: Effect of continued alcohol consumption on

bleeding and mortality after variceal haemorrhage, A1386MACDONALD, T T, and SPENCER, J: Induction of enteropathy by

activated T cells in human small intestine, A1334MCENTEE, G P, et al.: Current spectrum of intestinal obstruction,A1372

, et al.: Prospective study of alcohol induced pancreatitis: socialand surgical aspects, A371

MCFADDEN, J J, et al.: Use of cloned DNA probes to identify Crohn'sdisease microbial isolates, A1328

MACGILCHRIST, A J, et al.: Is sympathetic activity really increased incirrhosis with ascites?, A1394

,et al.: Is the reduced vascular tone in cirrhosis caused by'desensitisation' to sympathetic nervous activity?, A1349

MACGOWAN, s w, et al.: Experimental pancreatitis: the effect ofallopurinol, A368

MCINTYRE, A s, et al.: Human upper gastrointestinal transit andcarbohydrate absorption are modulated by beta-adrenoreceptors,A1396

, et al.: Palliation of malignant oesophageal strictures: prelimi-nary comparison of Atkinson tube and ACMI tumour probe intwo centres, A1380

MCKEE, R K, et al.: SMS 201-995 in the management of varicealbleeding, A1380

MCLAUCHLAN, G, et al.: Effect of omeprazole on postprandial gastricand duodenal pH in exocrine pancreatic insufficiency, A1340

Macrophages and lymphocytes, subpopulations in granulomata ofCrohn's disease, A1388

MAHIDA, Y R, et al.: Macrophage and lymphoid subpopulations in thegranulomata of Crohn's disease, A1388

MAHONY, M j, et al.: Campylobacter associated gastritis in children,A1357

MAIN, 1, et al.: Milk antibodies and circulating immune complexes ininflammatory bowel disease, A1387

Malignancy, gastroduodenal, Nd-YAG laser therapy in, A1374, hepatobiliary and pancreatic, cytological diagnosis of, A1401

-in Barrett's oesophagus, early detection of change to, value ofendoscopic surveillance in, A1379

, risk factors for, A1379MARSTON, J E, et al.: Desmosomes and human colorectal cancer,

A1368MARTIN, D F, et al.: Stone extraction after endoscopic sphincterotomy

- an active policy is best, A1360

1727

Index to abstracts

MATTHEWSON, K, et al.: Randomised comparison of Nd YAG laser,heater probe and no endoscopic therapy for bleeding peptic ulcer,A1342

Meal temperature, effect on gastric emptying of liquids, A1407Measles virus infection, persistent, due to defective measles virus

antigen expression in autoimmune chronic active hepatitis, A1346MELEAGROS, L, et al.: Acute intestinal ischaemia: differential

response of gut neuropeptides, A1334,et al.: Mouth-to-caecum transit time in man is reduced by a

novel serotonin M-receptor antagonist, A1373MERKI, H, et al.: Dose dependent inhibition of twenty four hour

intragastric acidity by WY-45,727 a new potent H2-receptorantagonist, A1339

MERTZ-NIELSEN, A, et al.: Acidification of the perfused humanstomach during muscarinic-M,-receptor blockade stimulatesgastric prostaglandin E2 output, A1411

Metallothionein and copper in liver disease with copper retention,histopathological study, A1348

Methane and hydrogcn, intracolonic concentrations in patients,A1370

Methyl tertiary butyl ether for common bile duct stones, dissolutionwithout radiological disappearance after, A1385

-, in vivo choledocholitholysis using, A1360N-Methyl-N'-nitro-N-nitrosoguanidine induction of changes in ratand human pepsinogen phenotypes, A1332

Metoclopramide for arrest of active bleeding from varices, trial of,A1380

Microbial isolates in Crohn's disease, identification with clonedDNA probes, A1328

MIGNON, M, et al.: Synthetic secretin secretolin: an adequate substi-tute to GIH natural secretin for secretin provocation test inZollinger-Ellison syndrome, A1407

MIKE, N, et al.: A specific small bowel enema appearance in non-

responsive coeliac disease, A1352Milk antibodies and circulating immune complexes in inflammatorybowel disease, A1387

MILLER, A, et al.: Diarrhoea is related to fat malabsorption andpartial villous atrophy in HIV infection in male homosexuals,A1353

MILLER, G, et al.: Smoking delays gastric emptying of solids, A1406MILLER, R, et a!.: Anorectal sensation: its role in the continencemechanism, A1361

,et al.: Consumer guide to anal manometry: a comparison ofmicrotransducer, water and air filled microballoon systems,A1361

,et al.: The sampling reflex: a comparison of normal andincontinent patients, A1361

MIRAKIAN, R, et al.: HLA D/DR Ag expression in the jejunum ofchildren with idiopathic protracted diarrhoea and circulatingenterocyte antibodies, A1355

Misoprostol and sucralfate in prevention of aspirin induced ulcera-tion, comparative study, A1338

Mitochondrial aspartate aminotransferase as marker for alcoholmisuse in patients with liver disease and controls, A1349

MORGAN, A G, et al.: Enprostil - an advance in gastric ulcer therapy?,A1336

MORIARTY, K J, et al.: Atrial natriuretic peptide influences electrolyte.transport in the large intestine, A1396

MORRIS, D L, et al.: Longterm results of albendazole therapy ofhydatid disease: clinical and experimental results, A1385

MOUNTFORD, R, et al.: Effect of treatment with famotidine on T-lymphocyte populations and activity in duodenal ulcer patients,A1338

Mouth-to-caecum transit time in man, reduction by ICS 205-930,A1373

Mucosa(l). See under Bronchial; Colon; Duodenum; Gastric;Gastroduodenal; Ileum; Jejunum

Mucosal injury, protective action of sucralfate against, influenced bypH?, A1338

Mucous cells, vacuolated, subnuclear, gastric and duodenal, A1408

Mucus glycoprotein biosynthesis, changes at tumour site in gastriccancer, A1332

synthesis and secretion int vitro by gastric mucosacolonised with Campylobacter pyloridis, A1409

'Mucus-bicarbonate' barrier, gastroduodenal, effect of indo-methacin, A1411

MULLER, C, et al.: Clinical results 10 years after proximal gastricvagotomy, A1404

MUNCK, L K, et al.: Prostaglandin E. is a mediator of 5-hydroxytryptamine induced fluid secretion in the human jejunum,A1396

MURPHY, M s, and EASIHAM, E J: Peptic ulcer in childhood: thelongterm prognosis, A1357

Muscarinic-Mi-receptor blockade, acidification of perfused humanstomach during, gastric prostaglandin E2 output stimulated by,A1411

MUTIMER, D, et al.: A medical/surgical team approach to themanagement of acute bleeding varices, A1386

Myopathy, skeletal, secondary to selenium deficiency, A1354,visceral, familial, A1399

NAIK, K s, et al.: The 'acid antrum' as a possible cause of recurrentulceration after highly selective vagotomy: a histological study,A1411

et at.: Basal and stimulated plasma gastrin in duodenalulceration: correlation with failure of H. receptor antagonists andwith recurrent ulceration after highly selective vagotomy, A1374

Neodymium-YAG laser photocoagulation in treatment of gastricvascular ectasia, A1370

therapy in gastric and duodenal malignancies, A1374Neoplasia, colonic, suspected, open access colonoscopy as single

investigation for, A1371,colorectal, left sided colonoscopy as screening procedure in

asymptomatic volunteers -45 years for, A1367Neoplasms, intrahepatic, interstitial hyperthermia as new thcrapy

for, A1350Neoplastic lesions detected at colonoscopy, diagnosis of, histologyand cytology compared for, A1343

NEOPTOLEMOS, J P, et al.: Multivariate analysis of risk factors inpatients undergoing surgery and/or endoscopic sphincterotomyfor common bile duct stones, A1383

,et al.: Outcome of patients with acute cholangitis and acutepancreatitis, A369

Neurological disorders, cisapride and gastrooesophageal reflux inchildren with and without, A1376

Neuropathy, pelvic floor, sensorimotor, comparison of diabetesmellitus and idiopathic faecal incontinence for, A1363

Neuropeptides in gut, differential response in acute intestinalischaemia, A1334

Neutrophils, superoxide production induced by acetaldehyde,penicillamine and cysteine inhibition of, A1331

NEWELL, s J, et al.: Gastro-oesophageal reflux in the preterm infant,A1357

Nicardipine, effect on anorectal function in normal controls andirritable bowel syndrome patients, A1364

NICHOLLS, R j, et al.: Internal anal sphincter function in neurogenicfaecal incontinence, A1364

Nizatidine, effect on gastric pH optimised by early evening mealwith drug, A1339

NO-rr, D M, et al.: Changes in the hepatic haemodynamics with thedevelopment of liver metastases, A1330

,aet al.: Effect of SMS 201-995 on the growth and developmentof hepatic metastases, A1350

Nutrition. See Enteral nutrition; Parenteral nutritionNutritional support in fulminant hepatic failure, safety of lipid

solutions for, A1347NZEGWU, H, et al.: Effects of starvation and refeeding on electrogenic

ion transport in the rat colon: a model for famine diarrhoca?,A1395

1728

Index to abstracts

Obesity, morbid, gastroplasty for, evaluation of nutritional effectsand surgical risks during 2 year study after, A1351

O'CONNOR, H J, et at.: Oesophageal cytology and biopsy: before orafter dilatation?, A1379

O'CONNOR, M P, et al.: H,- or '4C-breath tests in the diagnosis of smallintestinal bacterial overgrowth?, A1353

Oddi, sphincter of. See Sphincter of OddiO'DONNELL, L J, et al.: Bread is digested more slowly and incom-

pletely if made from coarse flour, A1352Oesophageal varices. See Varices, oesophageal-, bleeding. See Variceal haemorrhage, oesophageal

Oesophagitis, complicated, acid reflux patterns in, A1376, erosive, refractory to high dose cimetidine, value of omepra-

zole in management of, A1375[12 antagonists in, response predicted by physiological

studies?, A1358, reflux, healing and relapse after treatment with omeprazole 20

mg or 40 mg daily, A1376-, -, omeprazole or ranitidine in treatment of, Scandinavian

multicentre study, A1375,resistant, longterm treatment with omeprazole in,

effects on endoscopic healing and fasting serum gastrin levels,A1379,- ,treatment of, comparison of Asilone gel and Gaviscon

liquid for, A1376with prostaglandin analogue (trimoprostil), A1358

Oesophagus and stomach, benign and malignant diseases of, CA-5()in differential diagnosis of, A1405

Barrett's, malignancy in, risk factors for, A1379,malignant change in, early detection of, value of endo-

scopic surveillance in, A1379-,carcinoma of, intra-abdominal metastases for, detection of,

laparoscopy, ultrasound or CT for?, A1378,survival in, factors influencing, A1358

,cytology and biopsy, better before or after dilatation?, A1379function, influence of hiatal hernia, A1377

,motility disorders, manometric interpretation of oesophagealegg transit test as screening test for, A1358- pH, and gastric pH, monitoring of, ambulatory, 24 hour,

simultaneous, clinical applications of, A1377,- monitoring, 24 hour, expression of normal ranges in,

A1378- responses to distension, effects of cisapride, A1377,stricture dilatation with bougies and balloons, radial pressures

during, A1370,strictures of, benign, transthoracic colon interposition for,

A1378malignant, palliation of, comparison of Atkinson

tube and ACMI tumour probe in 2 centres, A1380, transit in patients with dysphagia, improvement by cisapride,

results of trial, A1377O'FARRELLY, c, et al.: Wheat protein, gut abnormalities and rheuma-

toid arthritis, A1398O'MAHONY, S, and WHELTON, M J: Immunofluorescent and genetic

studies of coeliac relatives of patients with dermatitis herpeti-formis: does sub-clinical DH exist?, A1352

Omeprazole and ranitidine in treatment of benign gastric ulcer,international multicentre study, A1340

*,effect on postprandial gastric and duodenal pH in exocrinepancreatic insufficiency, A1340

improvement of antral gastritis associated with duodenal ulcer,A1340

-in management of erosive oesophagitis refractory to high dosecimetidine, value of, A1375

or rantidine in treatment of reflux oesophagitis, Scandinavianmulticentre study, A1375

-treatment, longterm, in resistant reflux oesophagitis, effectson endoscopic healing and fasting serum gastrin levels, A1379

,- , serum gastrin concentrations and gastric endocrinecell population during, A1341

20 mg om and ranitidine 150 mg bd in healing of benign gastriculcers, Italian multicentre study, A1341

-or 40 mg daily, healing and relapse of reflux oeso-phagitis after treatment with, A1376

v ranitidine for duodenal ulcer, with weekly endoscopic assess-

ment, A1340in duodenal ulcer unhealed after 6 weeks' treatment

with H2-receptor antagonists, A1341Oncogene product, C-myc, expression in benign and malignant

gastric epithelia, A1404Osteocalcin, circulating, as index of bone turnover in primary biliary

cirrhosis pre- and post-liver transplantation, A1345Oxygen free radicals, zymogens of human pancreatic proteases not

activated by, A1394

Pain, biliary, acalculous, computer history analysis in, A1383,sphincter of Oddi motility in, A1384

-relief, postoperative, with diclofenac suppositories, A1397Pancreas, carcinoma of, diagnosis of, serum markers and clinical

data in, A370,enzyme linked lectin assay compared with RIA

CA19-9 as serum test for, A1401,glycoprotein marker for, new, carbohydrate

sequencing of, A1394related to, new, identification in serum by

electrophoresis and lectin blotting, A372,interstitial hyperthermia for treatment of, experi-

mental studies, A1382lectin histochemistry in, A369

exocrine function, prediction by faecal chymotrypsin in infantsand children, A1400

function test, oral, simplified and accurate, for use in children,A1356

-,morphological changes, suggesting endocrine regeneration,induced by transplantation of isolated hepatocytes, A1400

, resection using banding technique, long term experience of,A368

, surgery of, database for, design of, A372Pancreas divisum, chronic pancreatitis associated with, accessory

sphincteroplasty for, follow up of, A368Pancreatic and hepatobiliary malignancy, cytological diagnosis of,A1401

disorders, endoscopic ultrasound of, A1382enzyme secretion, stimulation by bombesin and meal, role of

cholecystokinin in, studied with CR 1409, A1381-insufficiency, exocrine, postprandial gastric and duodenal pH

in, effect of omeprazole, A1340non-isotopic test (PAS/PABA excretion ratio) for, with

differentiation from small bowel malabsorption, A1382proteases, human, zymogens of, not activated by oxygen free

radicals, A1394Pancreatic Society of Great Britain and Ireland: 11th Annual

Meeting, A367Pancreaticobiliary diversion, adaptive ileal mucosal hyperplasia in

rat after, inhibition by difluoromethyl-ornithine, A1394Pancreatitis, acute, biliary aetiology in, early diagnosis of, A370

,-, fresh frozen plasma in treatment of, intravenous or

intraperitoneal?, A1382multicentre clinical trial,

A367,primary, incidence and spatial distribution of patients in

Nottingham defined population, variations in (1969-85), A371,prognostic criteria in, critical evaluation, A368

- ,progress of, illness scoring systems for monitoring of,evaluation of, A1382,- reticuloendothelial system activity in rats with, effects of

SMS 201-995, A1381,risk of death from, A370serial computed tomography scanning in, A369severe, colonic complications of, A371

1729

Index to abstracts

severity of, serial objective measurement of, A369with acute cholangitis, outcome in, A369

biliary, acute, role of early ERCP and sphincterotomy in,A1384

, chronic, associated with pancreas divisum, accessorysphincteroplasty for, follow up of, A368

autoimmunity and HLA in, A371collagen quantification in, A372

experimental, effect of allopurinol, A368gall stone, sex differences in, A1383induced by alcohol, social and surgical aspects of study, A371, necrotising, acute, specific intraperitoneal antiproteinase

chemotherapy in, experimental study, A367Para-aminosalicylic acid. See PASParenteral nutrition, home, long term, worthwhile?, A1399PARKER, M, et al.: Combination antimycobacterial chemotherapy

with major clinical response in established Crohn's disease, A1390PARR, N, et al.: Mechanisms governing the biphasic pattern of gastricemptying after truncal vagotomy and pyloroplasty, A1332

PAS/PABA excretion ratio as non-isotopic test for pancreaticinsufficiency with differentiation from small bowel malabsorp-tion, A1382

Pelvic and spinal nerve injury, intractable constipation associatedwith, action of cisapride on, A1363

cytology, intraoperative, patients at risk of developing localrecurrence of colorectal cancer predicted by, A1368

floor neuropathy, sensorimotor, comparison of diabetesmellitus and idiopathic faecal incontinence for, A1363

PEMBERTON, P w, et al.: Electrophoretic analysis of microvillusmembranes in coeliac disease, A1335

PENA, A s, et al.: A prospective study of Campylobacter pyloridis bybacteriology, histology, urease test, and serology (ELISA andimmunoblotting), A1408

PENAGINI, R, et al.: Feedback regulation of transit and motility in thehuman jejunum and ileum by ileal infusion of glycochenodeoxy-cholic acid, A1398

, et al.: Glycochenodeoxycholic and glycocholic acids infusedin the human jejunum inhibit small bowel motility and transit,A1399

Penicillamine and cysteine inhibition of acetaldehyde inducedsuperoxide production by neutrophils, A1331

PENSTON, j, et al.: Recurrence of duodenal ulcers during mainten-ance treatment, A1375

Pepsin synthesis in man, measurement using 1-'3C-leucine, A1331Pepsinogen phenotypes, rat and human, changes induced by N-

methyl-N'-nitro-N-nitrosoguanidine in, A1332Pepsinogens, serum concentrations, effect of partial gastrectomy

with Billroth-I1 and Roux-en-Y anastomosis, prospective study,A1403

Peptic ulcer, acute complications of, highly selective vagotomy intreatment of, A1404

and polyunsaturated fatty acid ingestion, evidence fordirect relationship, A1411

bleeding, and aspirin, A1401comparison of Nd YAG laser, heater probe and no

endoscopic therapy for, A1342, intragastric fibrinolysis in, A1402

- in childhood, longterm prognosis, A1357Peptide histidine isoleucine. See PHIPeptides and amino acids, orally administered, influence on protein

turnover kinetics in short bowel syndrome, A1397Personality in inflammatory bowel disease, primary or secondary to

chronic illness?, A1388Phenolphthalein, laxative action on intestinal fluid absorption,mechanism of, A1336

PHI and VIP, different effects on intestinal adenylate, A1393PHILLIPS, A J, and LEATHARD, H L: Mechanism of laxative action of

phenolphthalein fluid absorption, A1336Phosphatidylcholine degradation in small intestinal bacterial over-

growth, A1397

Photocoagulation with Nd YAG laser in treatment of gastricvascular ectasia, A1370

Photodynamic therapy for colorectal cancer, A1368Pirenzepine blockade, acidification of perfused human stomach

during, gastric prostaglandin E, coutput stimulated by, A1411Plasma, fresh frozen, in treatment of acute pancreatitis, multicentre

clinical trial, A367therapeutic, in acute pancreatitis, intravenous or

intraperitoneal?, A1382Pneumatosis coli, breath hydrogen monitoring in, A1366Polyposis coli, juvenile, as precancerous condition, A1367Polyps, malignant, colonoscopic management of, audit of, A1367POMARE, E w, et al.: Portal and peripheral blood short chain fatty acid

concentrations after caecal lactulose installation at surgery, A1355Porphyria, hepatic, acute, haem arginate therapy for, A1347Portal hypertension and cirrhosis, portal haemodynamics in, effect

of high and low protein meals, A1349-tract lymphocyte populations in primary sclerosing cholangitis,A1330

PORTINCASA, P, et al.: An integrated study of gall bladder motorfunction in gall stone patients, A1395

Potassium transport and sodium transport, colonic, differentialeffects of mineralocorticoid and glucocorticoid hormones, A1335

POWER, R F, et al.: Localisation of VIP binding sites in human andguinea pig gut using in vitro autoradiography. A1333

PRICHARD, P j, et al.: Aspirin and bleeding peptic ulcer, A1401et al.: Fish oil for inflammatory bowel disease?, A1391et al.: Gastric mucosal bleeding: what dose of aspirin is safe?,

A1401PRIMROSE, J N, et al.: Somatostatin analogue SMS 201-995 in thedumping syndrome: effect on packed cell volume, blood glucoseand plasma GI peptides, A1396

Proctocolectomy and ileo-anal anastomosis, restorative, discrimina-tion not impaired by excision of anal transitional zone after, A1365

, restorative, outcome of, factors influencing, A1365Propranolol and sclerotherapy for prevention of rebleeding from

oesophageal varices, trial of, A1359Prostaglandin E2 and leucotriene B4 production, effects of pred-

nisolone, sulphasalazine, 5-aminosalicylic acid and indo-methacin, A1390

mediation of 5-hydroxytryptamine induced fluid secretionin human jejunum, A1396

-output, gastric, stimulation by acidification of perfusedhuman stomach during muscarinic-M1-receptor blockade, A1411

analogues. See TrimoprostilProtein meals, high and low, effect on portal haemodynamics in

cirrhosis and portal hypertension, A1349-turnover kinetics in short bowel syndrome, influence of orally

administered amino acids and peptides, A1397Puborectalis, lateral division of, for severe constipation, experience

of, A1364PUNTIS, J W L, et al.: Simplified and accurate oral pancreatic function

test for use in children, A1356PURI, P, et al.: Diagnosis of allied functional bowel disorders usingmonoclonal antibodies and electron microscopy, A1373

PYE, G, et al.: Effect of dietary fibre supplementation on colonic pHin healthy volunteers, A1366

et al.: Screening for colorectal cancer - an analysis of 132tumours, A1344

Ranitidine and indomethacin, effect on gastric acidity, A1373and intravenous BMY-25368-01, effect on meal stimulated

gastric acid secretion in man, A1339and Maalox TC tablets in healing of duodenal ulcer, compara-

tive multicentre study, A1337and omeprazole in treatment of benign gastric ulcer, inter-

national multicentre study, A1340150 mg bd and omeprazole 20 mg om in healing of benign

gastric ulcers, Italian multicentre study, A1341

1730

Index to abstracts

or omeprazole in treatment of reflux oesophagitis, Scandi-navian multicentre study, A1375

l} omeprazole for duodenal ulcer, with weekly endoscopicassessment, A1340

in duodenal ulcer linhealed after 6 weeks's treatment

with 112-receptor antagonists, A1341RAO, S S C, et al.: Enteral nutrition in severe colitis, A1328

,et al.: Studies on the anorectal function in ulcerative colitis,A1392

Rectal prolapse, anterior mucosal prolapse, solitary rectal ulcer,caused hy rectal herniation through weak sphincter?, A1363

ulcer, solitary, syndrome of, rectopexy for, outcome predictedby videoproctography and anorectal physiology?, A1361

Rectum and colon, biopsies, histopathological assessment of,observer variation in, A1389

,gluten challenge in coeliac sprue, sequence of immunopatho-logical events after, A1392

Red blood cell scintigraphy, ))mTc-labelled, in vivo, role in lowergastrointestinal haemorrhage, A1367

REES, RG, et al.: Influence of orally administered amino acids andpeptides on protein turnover kinetics in the short bowel syn-

drome, A1397Reflux, acid, patterns in complicated oesophagitis, A1376

, duodenogastric, continuous ambulatory monitoring withenzymatic amperometric bile acid electrode, in vitro feasibilitystudy, A1395

,non-invasive assessment by 'TFc'-EHIDA/externalimaging, validation of, A1408

gastritis, diagnosis of, value of alkali infusion test in, andcomparison with9Tc-HIDA test, A1408

, gastrooesophageal, and cisapride in children with and withoutneurological disorders, A1376

gastric adaptive relaxation in, A1376in preterm infant, A1357

oesophagitis, healing and relapse after treatment with omepra-

zolc 20 mg or 40 mg daily, A1376, omeprazole or ranitidine in treatment of, Scandinavian

multicentre study, A1375resistant, longterm treatment with omeprazole in,

effects on endoscopic healing and fasting serum gastrin levels,A1379

, treatment of, comparison of Asilone gel and Gavisconliquid for, A1376

,- with prostaglandin analogue (trimoprostil), A1358Reticuloendothelial system activity in rats with acute pancreatitis,

effects of SMS 201-995, A1381Rheumatoid arthritis, role of wheat protein and gut abnormalities

in, A1398RILEY, S A, et al.: A comparison of delayed-relcase 5-aminosalicylic

acid and sulphasalazine as maintenance treatment of ulcerativecolitis, A1390

et al.: Delayed-release 5-aminosalicylic acid and sulpha-salazine in the treatment of mild to moderate ulcerative colitisrelapse, A1329

Ritiometan, effect on food pseudo allergy, A1352ROBERTSON, C S, et al.: Dysphagia for solids is a longterm effect of the

Angelchik antireflux prosthesis, A1378, et al.: Value of endoscopic surveillance in the early detection

of malignant change in Barrett"s oesophagus, A1379ROBERTSON, D A F, et al.: Defective measles virus antigen expression

causes pcrsistent MV infection in autoimmune chronic active

hepatitis, A1346et al.: H2 antagonists in oesophagitis: can physiological studies

predict the response?, A1358-,et al.: Lung permeability in inflammatory bowel disease and

coeliac disease, A1336,et at.: Patterns of acid reflux in complicated oesophagitis,

A1376, etal.: Personality in inflammatory bowel disease: primary, or

secondary to chronic illness?, A1388

ROBERiSON, J F R, etal.: Patients with ampullary carcinomat are prone

to other malignant tumours, A370RODDIE, M E, et al.: Diagnosing inflammatory bowel disease with Tc99m IIMPAO labelled leucocytes. A1328

RODRIGUES, C A, etal.: Familial viscerall myopathy. A1399ROEtIGER, W E w, and NANCE, S H: Inhibition of fatty acid oxidation as

a cause of ulccrative colitis, A1387ROGERS, j, et al.: Combined sensorimotor deficit in primary neuro-

pathic faccal incontinence, A1363, et al.: Increased segmentall activity and intraluminal pressures

in the sigmoid colon of patients with the irritabie bowel syndrome:a new manometric technique, A1344

, et al.: Sensorimotor pelvic floor neuropathy: a comparison ofdiabetes mellitus and idiopathic faccal incontinenec, A1363

ROGERS, M, et al.: Highly selective vagotomy in the treatment of acutecomplications of peptic ulecr, A 1404

ROKKAS, et al.: Colloidal bismuth subeitrate (De-Nol) in non-ulcerdyspepsia: placebo controlled trial with particular refercnce to therolc of Camnpylobacter pyloridis, A 1337

Rotavirus infection, effect on water transport in infant mouse

intestine in vitro, A1334ROWE, P H, et al.: Restitution of colonic mucosa in vitro, A1395RUMESSEN, J j, and GUDMANI)-H0YER, E: Fructose and sorbitol

malabsorption in patients with functional bowel discasc, A1372

Sacral nerve, anterior, root stimulation, proximal extent anddifferential effects on colonic motility, A1363

SANDLE, G i, and MCGLONE, F: Differential effects of pure mineralo-corticoid and glucocorticoid hormones on colonic Na+ and K+transport, A1335

Segmcntal variability of electrogcnic Na+ transport inhuman colon, A1335

SATO, M, et al.: Effects of vitamin E deficiency on small intestinaltransport function, A1354

SAVERYMuFIJU, S H, et al.: Ultrasound identification of ocsophagealvarices- comparison with endoscopy, A1359

SCHLUP, M, et al.: Breath hydrogen monitoring in Pneurnatosis coli,A1366

SCHUERER-MALY, c-c, et al.: Smoking and pl1-responsc to H,-receptor antagonists, A1406

Scintigraphy, red blood cell, 9"Tc-labelled, in vivo, role in lowergastrointestinal hacmorrhagc, A1367

Seclerotherapy and propranolol for prevention of rcblceding fromoesophageal variccs, trial of, A 1359

,endoscopic, and transhepatic embolisation in patients withsevere cirrhosis and acute variecal bleeding, trial of, A1348

Secretin provocation test in Zollinger-Ellison syndrome, syntheticsecretin secretolin as substitute for GIH natural secretin in, A1407

SELDEN, c, and HODGSON, H J F: Synergism of hepatotropin, a novelhepatotrophic factor, and insulin on DNA in rat hepatocytes,A1393

Selenium deficiency, skeletal myopathy sccondary to, A1354Sensorimotor deficit, combined, in primary ncuropathic faccal

incontinence, A1363Sepsis, anorcctal, fistulac in, rcelvance of microbiology and neces-

sity of repeat examination under anaesthesia, A1369,intra-abdominal, occult, diagnosis with "'Indium labellcd

leucocyte scanning, carly v late scanning in, A1403

Septic complications, acute, of diverticular diseasc, survivalimproved by radical approach in, A1343

Serotonin M-receptor antagonists. See ICS 205-930Sex and age dependencc of entcrochromaffin-likc ccil populations,A1410

differences in gall stone pancrcatitis, A1383

SHARP, J F, et al.: Role of in vivo tcchnctium labellcd rcd blood cellscintigraphy in lower gastrointestinal haemorrhagc, A 1367

SHIRAZI-BEECHEY, S P, et al.: Preparation of osmotically activc brushborder membrane vesicles from biopsy samples of human small

intestine, A1333

1731

Index to abstracts

SHORROCK, c J, and REES, W D w: Effect of indomethacin on humangastroduodenal 'mucus-bicarbonate barrier, A1411

,et al.: Effect of bismuth subcitrate on gastric bicarbonatesecretion in vitro and in man, A1342

SHORVON, P j, et al.: Defecographic findings in young healthyvolunteers, A1361

, et al.: Endoscopic ultrasound of pancreatic disorders, A1382Sigmoid colon in irritable bowel syndrome, increased segmental

activity and intraluminal pressures in, recorded with new mano-metric technique, A1344

Skeletal myopathy secondary to selenium deficiency, A1354SMART, H L, and ATKINSON, M: Abnormal vagal function in the

irritable bowel syndrome, A1344-,-:Comparison of Asilone gel and Gaviscon liquid in the

treatment of reflux oesophagitis, A1376,et al.: Treatment of reflux oesophagitis with a prostaglandin

analogue, A1358SMITH, J A, and LONG, R G: Different effects of VIP and PHI on

intestinal adenylate, A1393,et al.: Use of endoscopic biopsies to diagnose disaccharidase

deficiencies, A1398Smoking and pH responsc to H2-receptor antagonists, A1406

and sugar intake in Crohn's disease, separate but interactiverisk factors, A1389

gastric emptying of solids delayed by, A1406mucosal gastrin and gastric acid secretion in duodcnal ulcer

affected by, A1374SMS 201-995, effect on growth and development of hepatic meta-

stases, A1350, effects on reticuloendothelial system activity in rats with

acute pancreatitis, A1381in dumping syndrome, effect on packed cell volume,

blood glucose and plasma GI peptides, A1396in management of variceal bleeding, A1380

SNOOK, J A, et al.: Portal tract lymphocyte populations in primarysclerosing cholangitis, A1330

Sodium and chloride transport mcchanisms and effects of shortchain fatty acids in human infant colon, A1366

-transport and potassium transport, colonic, diffcrential effectsof pure mineralocorticoid and glucocorticoid hormoncs, A1335

, electrogenic, in colon, segmental variability of, A1335Somatostatin release, gastric, fat as luminal stimulus for, A1331

, postprandial, in man, gastric acid regulation of, A1331Sorbitol and fructose malabsorption in functional bowel disease,A1372- malabsorption in normal and coeliac subjects, A1353Sphincter, anal, internal, function in neurogenic faccal inconti-

nence, A1364, weak, rectal herniation through, rectal prolapse,

anterior mucosal prolapse, solitary rectal ulcer caused by?, A1363of Oddi dysfunction, quantitative 99m-Tc DISIDA scanning in,

A1381motility in acalculous biliary pain, A1384

Sphincteroplasty, accessory, for chronic pancreatitis associated withpancreas divisum, follow up of, A368

Sphincterotomy and early ERCP, role in acute biliary pancreatitis,A1384

,endoscopic, for common bile duct calculi in patients with gallbladder in situ unfit for surgery, A1371-, -, stone extraction after, active policy for, A1360SPILLER, R c, et al.: Segmental colonic transit in ulcerative colitis -

effect of Asian versus Caucasian diet, A1366Spinal and pelvic nerve injury, intractable constipation associated

with, action of cisapride on, A1363SPRENGERS, D, et al.: Biphasic diurnal pattern of onset of bleeding

from oesophageal varices, A1380-, etal.: Is bleeding time a useful test in cirrhotic patients'?, A1348Sprue, coeliac, rectal gluten challenge in, sequence of immuno-

pathological events after, A1392SRAI, S K s, etal.: Developmental changes in the villous uptake of iron

and enterocyte iron binding proteins in the guinea pig duodenum,A1333

Starch absorption, inhibition by dietary fibre, A1354SlARKEY, w G, et al.: Effect of rotavirus infection on water transport

in infant mouse intestine in vitro, A1334SIlEGER, A c, et al.: Experimental studies on interstitial hyperthermia

for treating pancreatic cancer, A1382, et al.: Gastrointestinal bleeding from other sources in patients

with colonic angiodysplasia, A1355,et al.: Interstitial hyperthermia - a new therapy for intra-

hepatic neoplasms, A1350STOKER, D L, and WILLIAMS, J G: Enterohepatic circulation patterns inman, A1385

SJOKES, M A, et al.: Is long term home parenteral nutrition worth-while'?, A 1399

, et al.: Studies on the genesis of colic, A1372Stomach and oesophagus, benign and malignant diseases of, CA-SO

in differential diagnosis of, A1405human, perfused, acidification during muscarinic-M,-receptor

blockade, gastric prostaglandin E2 output stimulated by, A1411See also Gastric

Stones. See CalculiStrictureplasty for Crohn's disease, 9-year experience, A1329Substance P and calcitonin gene related peptide, nerves containing,

distribution in liver, immunohistochemical study, A1330Sucralfate and misoprostol in prevention of aspirin induced ulccra-

tion, comparative study, A1338,protective action against mucosal injury, influenced by pH?,

A1338v cimetidine for treatment of duodenal ulcer associated antral

gastritis, A1338Sugar intake and smoking in Crohn's disease, separate but inter-

active risk factors, A1389Sulphasalazine and 5-aminosalicylic acid, delayed-release, in treat-ment of mild to moderate ulcerative colitis relapse, A1329

as maintenance treatment for ulcerative colitis, comparisonwith delayed-release 5-aminosalicylic acid, A1390

Sulphation and desulphation in normal liver and primary biliarycirrhosis, A1345

SUN, w M, and READ, N w: Rectal prolapse, anterior mucosalprolapse, solitary rectal ulcer: are they caused by rectal herniationthrough a weak sphincter?, A1363

,et al.: Effect of meal temperature on gastric emptying ofliquids in man, A1407

,et al.: Effect of nicardipine on anorectal function in normalcontrols and IBS patients, A1364

SUNDERLAND, G T, et al.: Computer history analysis in acalculousbiliary pain, A1383

,et al.: Gall bladder motility in the presence of gall stones,A1360

,et al.: Sphincter of Oddi motility in acalculous biliary pain,A1384

Superoxide production by neutrophils induced by acetaldehyde,penicillamine and cysteine inhibition of, A1331

SURGICAL RESEARCH SOCIEIY 'COLON CLUB': National audit of compli-cated diverticular disease, A1343

Sympathetic nervous activity, 'desensitisation' to, reduced vasculartone in cirrhosis caused by?, A1349

-, incrcased in cirrhosis with ascites?, A1394

T cell populations and activity in duodenal ulcer, effect of famoti-dine treatment, A1338

cells, activated, induction of enteropathy in human smallintestine by, A1334

TALBO I, I C, et al.: The histopathology and staging of carcinoma of theampulla of Vater, A1400

lAM, P K H: Paediatric upper GI endoscopy - an experience of 531cases, A1370

Pathophysiology of childhood duodenal ulcer, A1357

1732

Index to abstracts

Tamoxifen, adjuvant, in treatment of.gastric carcinoma, controlledstudy. A1404

IAIE, J J T, et al.: Histology and cytology compared for the diagnosisof neoplastic lesions detected at colonoscopy, A1343

'I'AYLOR, c J, et al.: Absence of secretory response in jejunal biopsiesfrom children with cystic fibrosis, A1356

'I'AYIOR, D, et al.: Combination chemotherapy in hydatid disease,A1346

IAYLOR, tI' v, and BLOWER, A L: Isolated duodenal tamponade in thetreatment of bleeding duodenal ulcer, A1373

Temperature of meal, effect on gastric emptying of liquids, A1407TERRY, T R, et al.: Specific intraperitoneal antiproteinase chemo-

therapy in acute necrotising pancreatitis: an experimental study,A367

IHEODOSSI, A, et al.: Observer variation in the histopathologicalassessment of rectal and colonic biopsies, A1389

tIiOMPSON, i w, et al.: Gastric and duodenal subnuclear vacuolatedmucous cells, A1408

Thyroid function as prognostic indicator in cirrhosis, A1386Tobramycin, oral, outcome of acute ulcerative colitis improved by,A1390

Tomography, computed. See Computed tomographypotential, applied, for non-invasive measurement of gastric

emptying, A1410Transhepatic embolisation and endoscopic sclerotherapy in patients

with severe cirrhosis and acute variceal bleeding, trial of, A1348Transplantation of isolated hepatocytes, morphological changes in

pancreas, suggesting endocrine regeneration, induced by, A1400of liver. See Liver transplantation

Transplants, small bowel, successful, in rat, denervation primecause of reduced water absorption in, A1335

Triglyceride metabolism, effect of obstructive and hepatocellularjaundice, A1349

Trimoprostil treatment of reflux oesophagitis, A1358Tripotassium dicitrato bismuthate. See De-NolTrypsin, serum levels after various forms of gastric surgery, effect of

bombesin, A1381'I'UDOR, R G (for Surgical Research Society 'Colon Club'): National

audit of complicated diverticular disease, A1343Tumours, endocrine, in ARG-vasopressin/simian virus 40 large T

antigen transgenic mice, model for human multiple endocrineneoplasia type I syndrome?, A1393

Ulcer. See untder Duodenum; Gastric; Peptic; RectalUlceration induced by aspirin, prevention of, comparative study of

misoprostol and sucralfate in, A1338,recurrent, after highly selective vagotomy, 'acid antrum' as

possible cause of, histological study, A1411Ulcers, bleeding, active, endoscopic adrenaline injection for, con-

trolled asscssment, A1402,- , standard, blood loss from, effect of submucosal adrena-

line, A1402with non-bleeding visible vessels, multipolar electrocoagula-

tion in treatment of, trial of, A1342Ultrasound, endoluminal, in benign anorectal disease, A1369

, endoscopic, of pancreatic disorders, A1382identification of oesophageal varices, comparison with endo-

scopy, A1359Urea, oral, in treatment of hyponatraemic ascites, A1386Urease test, rapid, 4-hour, sensitivity and specificity to culture and

histology for detection of Campylobacter pyloridis in gastric andduodenal biopsies, A1406

Ursodeoxycholic acid and chenodeoxycholic acid, combined treat-ment with, bile lipid and gall stone dissolution responses to, A1360-treatment and postulated mechanism of calcification of

radiolucent gall stones, A1385

Vagal function, abnormal, in irritbtble bowel syndrome, A1344Vagotomy, diarrhoea after, impaired gastric adaptive relaxation in

patients with, A1403

,effect on Ca,npylobacter pyloridis, A1410gastric, proximal, clinical results 10 years after, A 1404highly selective, for duodenal ulcer, long term assessment of

efficacy, A1374in treatment of acute complications of peptic uilcer,

A1404,recurrent ulceration after, 'acid antrum' as possible

cause of, histological study, A1411-, truncal, and pyloroplasty, gastric emptying after, mechanisms

governing biphasic pattern of, A1332VAIRA, D, et al.: Comparative study of 4-hour rapid urease test to

culture and histology for the detection of Campylobacterpyloridisin gastric and duodenal biopsies, A1406

Variceal haemorrhage, active, metoclopramide for arrest of, trial of,A1380

, acute, and severe cirrhosis, endoscopic sclerotherapy andtranshepatic embolisation in patients with, trial of, A1348

,management of, medical/surgical tcam approachto, A1386

bleeding and mortality after, effect of continued alcoholconsumption, A1386

hepatic venous pressure gradient increased by carbo-hydrate meals in cirrhotics after, A1348

,oesophageal, onset of, biphasic diurnal pattern of, A 1380, surgical management of, Warren shunt v lienorenal

shunt for, 15 years' experience, A1386, SMS 201-995 in management of, A1380

Varices, oesophageal, rebleeding from, propranolol and sclero-therapy for prevention of, trial of, A1359,-, ultrasound identification of, comparison with cndo-

scopy, A1359Vasoactive intestinal peptide. See VIPVater's ampulla. See Ampulla of VaterVICKERS, c, et al.: Liver transplantation for fulminant hepatic failure,A1345

,et al.: Prospectivc controlled trial of propranolol and sclero-therapy for prevention of rebleeding from ocsophageal varices,A1359

Videoproctography and anorectal physiology, outcome after recto-pexy for solitary rectal ulcer syndrome predicted by?, A1361

Villous atrophy, partial, and fat malabsorption, diarrhoea relatedto, in HIV infcction in male homosexuals, A1353

VIP and PHI, diffcrent effects on intestinal adenylate, A1393binding sites, localisation in human and guinea pig gut using iI

vitro autoradiography, A1333Visceral myopathy, familial, A1399Vitamin B12, food bound, assimilation of, effects of 'mucosal

protective' and antisecretory drugs, A1341E deficiency, effccts on small intestinal transport function,

A1354

WALAN, A, et al.: Omeprazole and ranitidine in the treatmcnt ofbenign gastric ulcer- an international multicentre study, A1340

WALT, R P, et al.: Effect of indomethacin and ranitidine on gastricacidity, A1373

WARD, D c, et al.: Validation of non-invasive assessment of duo-denogastric reflux, A1408

Water absorption, reduction in successful rat small bowel trans-plants, dencrvation prime cause of, A1335

transport in infant mouse intestine in vitro, effect of rotavirusinfection, A1334

WA'rSON, A: Factors influencing survival in oesophageal cancer,

A1358WA'I'SON, A J M, et al.: Acetate uptake in rat small intestine is notsodium dependent, A1335

, et al.: Denervation is the prime causc of reduccd waterabsorption in successful rat small bowel transplants, A1335

WATSON, R G P, et at.: Circulating osteocalcin as an index of boncturnover in primary biliary cirrhosis pre- and post-liver transplan-tation, A1345

1733

Index to abstracts

WATSON, s, et al.: Gastrin - in vitro and in vivo studies in gastric andcolorectal cancer, A1332

WAIT, I, et al.: Laparoscopy, ultrasound or CT in the detection ofintra-abdominal metastases for oesophageal cancer?, A1378

Weight loss and gastric emptying, effect of Garren gastric bubblewith or without 600 calorie diet, trial of, A1412

Wheat protein and gut abnormalities, role in rheumatoid arthritis,A1398

WHEATLEY, K E, et al.: Intragastric fibrinolysis in bleeding peptic ulcerdisease, A1402

White cells. See LeucocytesWILKINSON, M L, et al.: Natural history of primary sclerosing

cholangitis HLA antigens as predictors of prognosis, A1345WILLIAMS, A J K, and BARRY, R E: Penicillamine and cysteine inhibit

acetaldehyde induced superoxide production by the neutrophil,A1331

,et al.: Activated complement is cytotoxic to isolated rathepatocytes, A1394

-,et al.: Detection of the acetaldehyde adduct on hepatocytemembranes of rats fed ethanol, A1393

WILLIAMS, J, et al.: Intensive dietary counselling in adolescents withcystic fibrosis, A1352

WILSON, J A, et al.: CO2 v air - an evaluation of discomfort aftercolonoscopy, A1370

WINSLET, M c, et al.: Aetiology of continued 'defecation' in thepresence of loop ileostomy, A1365

,et al.: Colonic cellular proliferation rates in normal subjects:the effect of the faecal stream, A1366

, et al.: Factors influencing the outcome of restorative procto-colectomy, A1365

et al.: Faecal diversion in the management of Crohn's disease,A1344

et al.: Fistulae in anorectal sepsis: the relevance of micro-biology and necessity of repeat examination under anaesthesia,A1369

,et al.: Mucosal glycoprotein synthetase in Crohn's disease: aprotective mechanism?, A1388

,et al.: Sustained epithelial proliferation after faecal diversionfor Crohn's disease objective evidence of mucosal recovery,

A1391WY-45,727, dose dependent inhibition of 24 hour intragastric

acidity, A1339WYArTr, II, et al.: Campylobacter pyloridis in tropical Africa, A1409WYNNE, H, et al.: Liver volume, blood flow and perfusion fall in agingman - an explanation for altered drug metabolism in the elderly,A1347

YOSHIOKA, K, and KEIGHLEY, M R B: Physiological parameter shoulddictate the surgical management of longstanding idiopathicchronic constipation, A1362

, et al.: Clinical and physiological evaluation of postanal repair,A1362-, et al.: Does the position of the patient influence the results of

anorectal manometry?, A1362

Zollinger-Ellison syndrome, secretin provocation test in, syntheticsecretin secretolin as substitute for GIH natural secretin in, A1407

Zymogens of human pancreatic proteases, not activated by oxygen

free radicals, A1394

1734

GU T

Journal of the British Societyof Gastroenterology

VOLUME TWENTY EIGHT1987

EDITOR

J J MISIEWICZ

BOOK REVIEW EDITOR

D L WINGATE

Editorial CommitteeA ALLEN

S R BLOOM

R M CASE

R COCKEL

D COLIN-JONES

J H CUMMINGS

A CUSCHIERI

S J W EVANS

J F FIELDING

A GARNER

R C HEADING

R V HEATLEY

M R B KEIGHLEY

W R LEES

A S McNEISH

P J MILLA

T J PETERS

A B PRICE

N W READ

I TAYLOR

D TRIGER

G T WILLIAMS

ROGER WILLIAMS

R C N WILLIAMSON

EDITOR British Medical JournalSHIRLEY McGEALEY (Technical Editor)

BRITISH MEDICAL ASSOCIATIONTAVISTOCK SQUARE LONDON WC1

ContentsNo. 1 JANUARY 1987

PageLeading article: Functional gastroenterological disorders: the name's the thing N W READAlimentary tract and pancreas: Chronic idiopathic intestinal pseudo-obstruction: clinical and intestinalmanometric findings V STANGHELLINI, M CAMILLERI, AND J-R MALAGELADA ...............................5Effect of cisapride on the gastrointestinal transit of a solid meal in normal human subjects C A EDWARDS,S HOLDEN, C BROWN, AND N W READ .............. ................................................. 13Twenty four hour manometric recording of colonic motor activity in healthy man F NARDUCCI, G BASSOTTI,MGABURRI,ANDAMORELLI .................. 17Evaluation of gastric carcinoembryonic antigen analysis as an aid during screening for gastric neoplasia inatrophic gastritis K BORCH, H RENVALL, CHRISTINA LUNDIN, AND B WAHREN ............................... 26Enteroglucagon and experimental intestinal carcinogenesis in the rat A P SAVAGE, J L MATTHEWS, M A GHATEI,T COOKE, AND S R BLOOM . ........................................................................ 33Discriminant value of dyspeptic symptoms: a study of the clinical presentation of 221 patients with dyspepsiaof unknown cause, peptic ulceration and cholelithiasis N J TALLEY, D McNEIL, AND D W PIPER ..... ........... 40Specialist investigation of obscure gastrointestinal bleeding J N rHOMPSON, R R SALEM, A P HEMINGWAY,H C REES, H J F HODGSON, C B WOOD, D J ALLISON, AND J SPENCER ............ . ............................ 47Effect of chronic ethanol ingestion on enterocyte turnover in rat small intestine R MAZZANTI AND W J JENKINS 52Effect of chronic ethanol intake on lactase activity and active galactose absorption in rat small intestineR MAZZANTI, E S DEBNAM, AND W J JENKINS ......................................................... 56Teeth and benign oesophageal stricture D G MAXTON, C C AINLEY, S 1 GRAINGER, R W MORRIS, ANDRPHTHOMPSON. ........................................................................... 61Antecedent long term ethanol consumption in combination with different diets alters the severity ofexperimental acute pancreatitis in rats o JUHANI RAMO ............................................... 64In vitro effect of duodenal juice on R binders cobalamin complexes in subjects with pancreatic insufficiency:correlation with cobalamin absorption J BELAICHE, J ZITTOUN, J MARQUET, J YVART, AND D CATTAN .... ....... 70Liver and biliary: Penetration of albendazole sulphoxide into hyatid cysts D L MORRIS, J B CHINNERY,G GEORGIOU, G STAMATAKIS, AND B GOLEMATIS ................ . ...................................... 75Occasional report: Managing radical surgery: notes from the patient's viewpoint M P KELLY ..... .......... 81Clinical trial: Comparative trial of sodium cromoglycate enemas with prednisolone enemas in the treatmentof ulcerative colitis R H GRACE, A E GENT, AND M D HELLIER ............................................ 88Case report: Neurological sequelae in patients recovered from fulminant hepatic failure c J O'BRIEN,R J S WISE, J G O'GRADY, AND ROGER WILLIAMS ........ . ................................................. 93Progress report: Relationship between gastric secretion and infection C W HOWDEN AND R H HUNT .... ...... 96Referees .... 108Correspondence. Books. News ............... .................................................. 110

No. 2 FEBRUARY 1987

Leading article: Immunotherapy for cancer: the use of lymphokine activated killer (LAK) cells ELIZABETH AFAGAN AND ADRIAN LW F EDDLESTON ............ ................................................. 113Liver and biliary: Lysis of primary hepatic tumours by lymphokine activated killer cells KUE H HSIEH,SUYU SHU, CHUE S LEE, CHIEN T CHU, CZAU S YANG, AND KING J CHANG ................................... 117Porphyrin metabolism and haem biosynthesis in Gilbert's syndrome K E 1 MCCOLL, G G THOMPSON, E EL OMAR,M R MOORE, AND A GOLDBERG . .................................................................... 125Intragastric bile acid concentrations are unrelated to symptoms of flatulent dyspepsia in patients with andwithout gall bladder disease and postcholecystectomy R G P WATSON AND A H G LOVE ..... ................. 131Gall bladder emptying in normal subjects- a data base for clinical cholescintigraphy C R MACKIE, J N BAXTER,J S GRIME, G HULKS, AND A CUSCHIERI ............ ................................................. 137Endoscopic sphincterotomy and surgical approaches in the treatment of the 'sump syndrome' U A MARBET,G A STALDER, H FAUST, F HARDER, AND K GYR ....................................................... 142Alimentary tract and pancreas: Is there a relationship between symptoms of the irritable bowel syndromeand objective measurements of large bowel function? A longitudinal study G J OETrLE AND K W HEATON ..... 146Optimum dosage of ispaghula husk in patients with irritable bowel syndrome: correlation of symptom reliefwith whole gut transit time and stool weight ASHWINI KUMAR, NIRMAL KUMAR, J C VIJ, S K SARIN, AND B S ANAND 150Irritable bowel type symptoms in spontaneous and induced constipation s N MARCUS AND K W HEATON ....... 156Life events, psychiatric illness and the irritable bowel syndrome M J FORD, P MCC MILLER, JENNY EASTWOOD,ANDMAEASTWOOD ........................... 160Effects of peptide YY (PYY) on mouth to caecum intestinal transit time and on the rate of gastric emptyingin healthy volunteers A P SAVAGE, T E ADRIAN, G CAROLAN, V K CHATTERJEE, AND S R BLOOM ..... ............. 166

Contents

PageEffects of an elemental diet, inert bulk and different types of dietary fibre on the response of the intestinalepithelium to refeeding in the rat and relationship to plasma gastrin, enteroglucagon, and PYY concen-trations R A GOODLAD, W LENTON, M A GHATEI, T E ADRIAN, S R BLOOM, AND N A WRIGHT .... ................. 171Abnormal metabolism of arachidonic acid in chronic inflammatory bowel disease: enhanced release ofleucotriene B4 from activated neutrophils o H NIEI SEN, I AHNFELT-R0NNE, AND J ELMGREEN .... ............ 181Colonic bacterial proteases to IgAl and sIgA in patients with ulcerative colitis G D BARR, M J HUDSON,J D PRIDDLE, AND D PJEWELL . ................................................................... 186Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species Y MIYACHI,A YOSHIOKA, S IMAMURA, AND Y NIWA ............................................................. 190Metabolism and urinary excretion of 5-amino salicylic acid in healthy volunteers when given intravenouslyor released for absorption at different sites in the gastrointestinal tract B MYERS, D N W EVANS, J RHODES,B K EVANS, B R HUGHES, M G LEE, A RICHENS, AND D RICHARDS ........... 196Gastrocytoprotection by colloidal bismuth subcitrate (De-Nol) and sucralfate. Role ofendogenous prostaglandins S J KONTUREK, T RADECKI, IRENEUSZ PIASTUCKI, TOMASZ BRZOZOWSKI, ANDDANUTA DROZDOWICZ ................201.......................................................... 201Effect of intragastric pH on antral gastrin and somatostatin release in anaesthetised, atropinised duodenalulcerpatientsandcontrolss LJENSEN,JJ HOLST, LACHRISTIANSEN, M HSHOKOUH-AMIRI, M LORENTSEN, H BECK,AND H-EJENSEN ........................ ........................................................ 206Clinical markers of slow healing and relapsing gastric ulcer G BATTAGLIA, F DI MARIO, A PICCOLI, F VIANFLLO,F FARINATI, AND R NACCARATO .... . ............................................................... 210Urinary N-nitrosoproline excretion: a further evaluation of the nitrosamine hypothesis of gastriccarcinogenesis in precancerous conditions C N HALL, J S KIRKHAM, AND T C NORTHFIEID ..... ............... 216Clinical trials: Is bran efficacious in irritable bowel syndrome? A double blind placebo controlled crossoverstudy M R LUCEY, M L CLARK, JO LOWNDES, AND A M DAWSON ........................................... 221Randomised study of the influence of non-steroidal anti-inflammatory drugs on the treatment of peptic ulcerin patients with rheumatic disease C MANNICHE, A MALCHOW-M0LLER, J R ANDERSEN, C PEDERSEN, T M HANSEN,PJESS, 1 HELLEBERG, S N RASMUSSEN, U TAGE-JENSEN, AND S E NIELSEN .................................. 226Correspondence. Books. News . ................................................................ 230

No.3 MARCH 1987

Leading article: Fine needle biopsy: cytology, histology or both? M A HALL-CRAGGS AND W R LEES .... ....... 233Liver and biliary: Histologic differential diagnosis of focal liver lesions by ultrasonically guided fine needlebiopsy B LIMBERG, W W HOPKER, AND B KOMMERELL .................................................. 237Comparison of ultrasonography, computed tomography and `TC liver scan in diagnosis of Budd-Chiarisyndrome S GUPTA, S BARTER, G W L PHILLIPS, RN GIBSON, AND H J F HODGSON ............................. 242Enhanced oral bioavailability of meptazinol in cirrhosis G G BIRNIE, G G THOMPSON, T MURRAY, G WATKINSON,ANDM J BRODIE . ......................................................... ................. 248Comparative modes of action of lactitol and lactulose in the treatment of hepatic encephalopathy D H PATIL,D WESTABY, Y R MAHIDA, K R PALMER, R REES, M 1 CLARK, A M DAWSON, AND D B A SILK ....255................. 255Measurement and correlation of wedged hepatic, intrahepatic, intrasplenic and intravariceal pressures inpatients with cirrhosis of liver and non-cirrhotic portal fibrosis S K SARIN, K K SETHI, AND R NANDA .... ....... 260Electrohydraulic lithotripsy of gall stones in vitro and animal studies J HARRISON, D L MORRIS, JULIE HAYNES,A HITCHCOCK, C WOMACK, AND DC WHERRY ......................................................... 267Alimentary tract and pancreas: Motor responses of the oesophagus to intraluminal distension in normalsubjects and patients with oesophageal clearence disorders G P N KENDALL, D G THOMPSON, S J DAY, ANDNGARVIE ..................................................................................... 272Gastric acid and pancreatic polypeptide responses to modified sham feeding. Effects of truncal and parietalcell vagotomy S J KONTUREK, T POPIELA, M SLOWIACZEK, AND W BIELANSKI ............................... 280Molecular weight of gastric mucus glycoprotein is a determinant of the degree of subsequent aspirin inducedchronic gastric ulceration in the rat P F BAGSHAW, D J MUNSTER, AND J G WILSON .......................... 287Effect of bedtime ranitidine on overnight gastric acid output and intragastric pH: dose/response study andcomparison with cimetidine J B CHAMBERS, D PRYCE, J M BLAND, AND T C NORTHFIELD .... .................. 294Effect of chronic administration of cisapride on gastric emptying of a solid meal and on dyspeptic symptomsin patients with idiopathic gastroparesis R CORINALDESI, V STANGHELLINI, C RAITI, E REA, R SALGEMINI, ANDLBARBARA ............................................................ ....................... 300Gastric and duodenal polyps in familial adenomatous polyposis: a prospective study of the nature andprevalence of upper gastrointestinal polyps R G SARRE, A G FROST, D G JAGELMAN, R E PETRAS, M V SIVAK, ANDEMcGANNON ................................................................................. 306

Contents

PageMeasurement of arachidonate and its metabolites extracted from human normal and malignantgastrointestinal tissues A BENNETT, A CIVIER, C N HENSBY, P B MELHUISH, AND I F STAMFORD ..... ............. 315Gastric enzymes as a screening test for gastric cancer P J FINCH, F P RYAN, K ROGERS, AND S HOLT .... ......... 319Comparative effectiveness of the tumour diagnostics, CA 19-9, CA 125 and carcinoembryonic antigen inpatients with diseases of the digestive system K SAKAMOTO, Y HAGA, R YOSHIMURA, H EGAMI, Y YOKOYAMA, ANDM AKAGI ................................................................................... 323Raised serum concentrations of pancreatic enzymes in cigarette smokers M A DUBICK, C N CONTEAS, H T BILLY,A P N MAJUMDAR, AND M C GEOKAS ...................... 330Raised plasma concentrations of platelet factor 4 (PFA) in Crohn's disease M SIMI, S LEARDI, MARIA T TEBANO,M CASTELLI, F M COSTANTINI, AND V SPERANZA ......... ............................................. 336Immunohistochemical localisation of vitamin B12 R-binder in the human digestive tract H KUDO, M INADA,G OHSHIO, Y WAKATSUKI, K OGAWA, Y HAMASHIMA, AND T MIYAKE ....................................... 339Effects of olsalazine in the jejunum of the rat A Q M MOHSEN, D MULVEY, J D PRIDDLE, D S PARSONS, ANDD PJEWELL .................................................................................. 346Effect of aging on anorectal function J J BANNISTER, LABOUZEKRY, AND N W READ ......................... 353Case report: Periampullary cyst: a surgically remediable cause of pancreatitis I KALVARIA, P C BORNMAN,A H GIRDWOOD, AND I N MARKS ......... . .......................................................... 358Correspondence. Books. News. Correction ....................................................... 363

No. 4 APRIL 1987

Leading articles: Back to the future: or foward to the past? FT DE DOMBAL ..............................373The quality of life in Crohn's disease B G GAZZARD .................................................. 378Alimentary tract and pancreas: Life prospects and quality of life in patients with Crohn's diseaseV Z S0RENSEN, B G OLSEN, AND V BINDER . ........................................................... 382Faecal alpha-1-antitrypsin and excretion of "'Indium granulocytes in assessment of disease activity inchronic inflammatory bowel diseases w FISCHBACH, W BECKER, J MOSSNER, W KOCH, AND C REINERS .... ...... 386Histopathology of intestinal inflammation related to reactive arthritis c CUVELIER, C BARBATIS, H MIELANTS,M DE VOS, H ROELS, AND E VEYS .39..................................... ......................... 394Chronic ulcerative colitis: incidence and prevalence in a community c M STONNINGTON, S F PHILLIPS,LJ MELTON III, AND A R ZINSMEISTER ............... ................................................ 402Osteoporosis in patients with inflammatory bowel disease J E COMPSTON, D JUDD, E 0 CRAWLEY, W-D EVANS,C EVANS, H A CHURCH, E M REID, AND J RHODES ......... . .............................................. 410Tumour related inhibition of macrophage chemotaxis in patients with colon cancer A HERMANOWICZ,PRGIBSON, ANDD PJEWELL .................... ................................................. 416Hypnotherapy in severe irritable bowel syndrome: further experience P J WHOREWELL, ALISON PRIOR, ANDS M COLGAN .................................................................................. 423Cellular hypersensitivity to gluten derived peptides in coeliac disease R GUAN, P M RAWCLIFFE, J D PRIDDLE,AND D PJEWELL . ............................................................................. 426Enterocyte function in progressive systemic sclerosis as estimated by the deconjugation of pteroyltri-glutamate to folic acid L HENDEL, J HENDEL, AND I JOERGENSEN ....................................... 435Effect of oxytetracycline administration on intestinal metabolism of oestrogens and on plasma sex hormonesin healthy men E HAMALAINEN, J T KORPELA, AND H ADLERCREUTZ ...................................... 439Intestinal involvement in progressive systemic sclerosis detected by increased unconjugated serum bile acidsFSTELLAARD, TSAUERBRUCH, C H LUDERSCHMIDT, B LEISNER, AND G PAUMGARTNER ........................ 446Single dose treatment with H2 receptor antagonists: is bedtime administration too late? H MERKI, L WITZEL,K HARRE, E SCHEURLE, J NEUMANN, AND I ROHMEL ................ . ................................... 451Effects of nifedipine on gastric acid secretion and gastrin release in man K E L McCOLL, N M M BUCHANAN,G LAFERLA, J HEARNS, K BUCHANAN, AND G PCREAN .................................................. 455Ranitidine 150mg at night in the prevention of gastric ulcer relapse R JORDE, P G BURHOL, AND T HANSEN ..... 460Inhibition of meal stimulated gastric acid secretion by an octapeptide somatostatin analogue SMS 201-995J A OLSEN, F B LOUD, AND J CHRISTIANSEN .......................................................... 464Improved specificity of the PABA test with p-aminosalicylic acid (PAS) F J HOEK, F A J T M VAN DEN BERGH,J T KLEIN ELHORST, J L MEIJER, E TIMMER, AND G N TYTGAT ........ ................ . ...................... 468Special report: IOBD report no 1: observer variation in calculating indices of severity and activity in Crohn'sdisease FT DE DOMBAL AND A SOFTLEY .............. ............................................... 474Case report: Cytomegalovirus colitis and oesophageal ulceration in the context of AIDS: clinicalmanifestations and preliminary report of treatment with Foscarnet (phosphonoformate) J N WEBER, S THOM,I BARRISON, R UNWIN, S FORSTER, D J JEFFRIES, A BOYLSTON, AND A J PINCHING ............................. 482

Contents

PageProgress report: Achlorhydria: hypergastrinaemia: carcinoids - a flawed hypothesis? J PENSTON AND

KGWORMSLEY ................................................................................. 488Correspondence. Books. News . ................................................................ 506

No. 5 MAY 1987

Leading articles: Monitoring oesophageal pH M ATKINSON ........................................... 509NSAIDS - should every prescription carry a Government Health Warning? R COCKEL ............ ....... 515Alimentary tract and pancreas: Daytime gastro-oesophageal reflux is important in oesophagitis J S DECAFSTECKER, J N BLACKWEI L, A PRYDE, AND R C HEADING .............................................. 519Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulcerationCPARMSTRONG AND A LBIlOWER .............. . .................................................... 527Prognosis of chronic duodenal ulcer: a prospective study of the effects of demographic and environmentalfactors and ulcer healing RW NASIRY, J H MclNTOSH, K BYTH, AND D W PIPER .............................. 535Gastric mucosal protection with selective inhibition of thromboxane synthesis R P WALT, R I KEMP,B FILIPOWICZ, J G DAVIES, N K BHASKAR, AND C J HAWKEY .............................................. 541Transpyloric fluid movement and antroduodenal motility in patients with gastro-oesophageal refluxPM KING, A PRYDE, AND R C HEADING ....................................................... .... 545Does smoking interfere with the effect of histamine H2-receptor antagonists on intragastric acidity in man?P BAUERFEIND, TCILLUFFO, C J FIMMEL, C EMDE, C VON RIfER, W KOHL ER, R GUGLER, TGASSER, AND A I BlUM ... 549Comparison of maximal gastric secretion in smokers and non-smokers with and without duodenal ulcer P FWHITFIEL.D AND M HOBSI EY . ................................................................... 557Relationship of erosive gastritis to the acid secreting area and intestinal metaplasia, and thehealing effect of pirenzepine M TATSUTA, H IISHI, AND S OKUDA ....................................... 561Large single daily dose of histamine H2 receptor antagonist for duodenal ulcer. How much and when'? Aclinical pharmacological study M DEAKIN, HELEN P Gl ENNY, J K RAMAGE, JANE G MILLS, W L BURLAND, ANDJG WILLIAMS ................................................................................. 566Intravenous but not intragastric urogastrone-EGF is trophic to the intestine of parenterally fed ratsR A GOODLAD, T J G WILSON, W IFNTON, H GREGORY, K G McCULLAGH, AND N A WRIGHT .... .................. 573Effects of exercise on mesenteric blood flow in man M I QAMAR AND A E READ ............................ 583Spirochaetosis of the human rectum associated with an intraepithelial mast cell and IgE plasma cell responseJ-O GEBBERS, D J P FERGUSON, C MASON, P KEL Y, AND D PJEWELI. ....................................... 588Immunohistochemical Cal9-9 in primary colonic polyps and polyps synchronous with colorectal cancerN H AFDHAL, A LONG, I TOBBIA, A CULLEN, AND D P0 DONOGHUE ........................................ 594Effect of changing transit time on colonic microbial metabolism in man ALISON M STEPHEN, H S WIGGINS, ANDJ H CUMMINGS ....................... ..... .................................................. 601Immunoglobulin allotypes in Crohn's disease in the Netherlands I BIEMOND, GERDA G DE LANGE, IRENET WETERMAN, AND A S PENA . ..................................................................... 610Case Reports: Salicylate induced exacerbation of ulcerative colitis T K CHAKRABORTY, D BHATIA, R C HEADING,ANDMJ FORD ................................................................................. 613Protein losing enteropathy: an unusual presentation of intestinal schistosomiasis C F KIIRE AND N GWAVAVA . 616Clinical trial: Randomised controlled trial of lymphoblastoid interferon for chronic active hepatitis BM G ANDERSON, T J HARRISON, G ALEXANDER, A J ZUCKERMAN, AND I M MURRAY-ILYON ....................... 619Progress report: Problems of bacterial infection in patients with liver disease R J WYKE ..... .............. 623Correspondence. Books. News .............. ................................................... 642

No. 6 JUNE 1987

Leading articles: Variceal sclerotherapy: further progress P M SMITH ................................... 645The gut is a membrane, is a vesicle, is a gut! S PHIL LIPS ............................................... 650Liver and biliary: Variceal bleeding: does variable delay in trial entry invalidate comparison between trials?D BULLIMORE ................................................................................. 653Intravariceal versus paravariceal sclerotherapy: a prospective, controlled, randomised trial S K SARIN,R NANDA, G SACHDEV, S CHARI, B S ANAND, AND S I BROOR ......S....................................... 657Changes in blood flow, portal pressure and shunting during the development of cirrhosis in response tobeta-blockade M MCLAREN, S BRAYE, J Fl EMMING, S KARRAN, AND I TAYLOR ............................... 663Hepatic sarcomas in adults: a review of 25 cases A FORBES, B PORTMAN, P JOHNSON, AND ROGER WILLIAMS ...... 668

Contents

PageEffect of long term lactulose ingestion on secondary bile salt metabolism in man: potential protective effectof lactulose in colonic carcinogenesis G P VAN BERGE HENEGOUWEN, S D J VAN DER WERF, AND A TH RUBEN ...... 675Alimentary tract and pancreas: Jejunal water and electrolyte absorption from two proprietary enteral feedsin man: importance of sodium content R C SPILLER, B J M JONES, AND D B A SILK ........................... 681Small intestinal response to 'elemental' and 'complete' liquid feeds in the rat: effect of dietary bulkD G MAXTON, E U CYNK, AND R P H THOMPSON . .............................................. ........ 688[4C]-triolein absorption: a useful test in the diagnosis of malabsorption i M TURNER, S LAWRENCE,IW FELLOWS, I JOHNSON, PG HILL, AND G K T HOLMES ................................................. 694Acute effects of dexamethasone on cation transport in colonic epithelium G I SANDLE AND F McGLONE ....... 701Mucosal surface pH of the large intestine of the rat and of normal and inflamed large intestine in manN I McNEIL, K L E LING, AND J WAGER . .......................................................... 707Motor responses of the small intestine to intraluminal distension in normal volunteers and a patient withvisceral neuropathy G P N KENDALL, D G THOMPSON, AND S J DAY ....................................... 714Evaluation of the hydrogen breath test in man: definition and elimination of the early hydrogen peakG MASTROPAOLO AND WDW REES ...................... ...................................... 721Effects of one year's treatment with ranitidine and of truncal vagotomy on gastric contents i MEYRICK THOMAS,JJ MISIEWICZ, A RCOOK, MJ HILL, P LRSMITH, C LWALTERS, J K FORSTER, LEMARTIN, AND D FWOODINGS ........... 726Vagal cholinergic control of gastric alkaline secretion in normal subjects and duodenal ulcer patientsSJKONTUREK, NINA KWIECIEN,W OBTULOWICZ, PTHOR, JW KONTUREK, T POPIELA, AND J OLEKSY .... ............ 739Activation of peripheral blood and intestinal lamina propria lymphocytes in Crohn's disease. In vivo state ofactivation and in vitro response to stimulation as defined by the expression of early activation antigensF PALLONE, S FAIS, OSQUARCIA, L BIANCONE, P POZZILLI, AND M BOIRIVANT ................... . ............. 745Morphological and cell kinetic effects ofdietary manipulation during colorectal carcinogenesis D JGALLOWAY,FREDAJARRETT, PBOYLE, MALLIKAINDRAN, KATHARINECARR,RWOWEN, ANDWDGEORGE ..... ............... 754C-reactive protein (CRP) and serum phospholipase A2 in the assessment of the severity of acute pancreatitisPAULI PUOLAKKAINEN, VILLE VALTONEN, ANU PAANANEN, ANDTOM SCHRODER ............................. 764Occasional report: Future requirements for colonoscopy in Britain REPORT BY THE ENDOSCOPY SECTIONCOMMITTEE OFTHE BRITISH SOCIETY OF GASTROENTEROLOGY .......... ................................... 772Correspondence. Books. News. Correction ........... ............................................ 776

No. 7 JULY

Leadingarticles: Light at the end ofthe tunnel? Palliation foroesophageal carcinomai COX ANDJRBENNETT ... 781Anastomotic recurrence of colorectal cancer - a biological phenomenon or an avoidable calamity?MRBKEIGHLEYAND CHRISTINE HALL ................ ............................................... 786Alimentary tract and pancreas: Palliative laser therapy for malignant dysphagia N KRASNER, H BARR, CAROLESKIDMORE,AND A I MORRIS . ..................................................................... 792Endoscopic laser palliation for advanced malignant dysphagia S G BOWN, R HAWES, K MATTHEWSON, C P SWAIN,HBARR,P B BOULOS, AND CGCLARK ................................................................ 799Proliferative instability and experimental carcinogenesis at colonic anastomoses R ROE, B FERMOR, ANDRCN WILLIAMSON ................................ 808Plasminogen activators in experimental colorectal neoplasia: a role in the adenoma-carcinoma sequence?JS K GELISTER, M R LEWIN, H EDRIVER, FSAVAGE, M MAHMOUD, PJGAFFNEY, AND PB BOULOS ..... ............... 816Development of phospholipase A2 and lysophosphatidylocholine metabolising enzyme activities in theneonatal rat intestine cTAGESSON, ETELEMO, G EKSTROM, AND B WESTROM ................................ 822Effects of auranofin and myochrysine on intestinal transport and morphology in the rat H V AMMON, S A FOWLE,JA CUNNINGHAM, R A KOMOROWSKI, AND R F LOEFFLER .................................................. 829Formation of a fibrin based gelatinous coat over repairing rat gastric epithelium after acute ethanol damage:interaction with adherent mucusLA SELLERS, A ALLEN, AND M K BENNETT ................................ 835Inhibition of the effect of serotonin on rat ileal transport by cisapride: evidence in favour ofthe involvement of5-HT2 receptorsKJMORIARTY, N B HIGGS, M WOODFORD, G WARHURST, AND LATURNBERG ..... ............... 844Adaptation of hydrogen analysis to measure stomach to caecum transit time in the rat NICOLA J BROWN,RDERUMSEY,ANDNWREAD. .................................................................... 849Relationship between gastric emptying of a solid meal and emptying of the gall bladder before and aftervagotomyJN BAXTER, J SGRIME, M CRITCHLEY, S A JENKINS, AND R SHIELDS ................................. 855Modulation of human upper gastrointestinal motility by rectal distension J E KELLOW, R C GILL, ANDDAVID LWINGATE .......... 864Preoperative and intraoperative localisation of gastrointestinal bleeding of obscure origin w Y LAU, S T FAN,SHWONG,K PWONG,G P POON, KW CHU, W C YIP, AND K KWONG .......................................... 869

Contents

PatgeDistribution of the 10 000 molecular weight calcium binding protein along the small and large intestine of man

MSTAUN ..................................................................................... 878Twenty four hour oesophageal acidity in achalasia before and after pneumatic dilatation H 1. SMART, P N FOS IIER,DE- EVANS,BSLEVIN,ANDMATKINSON .................... 883Telenzepine is at least 25 times more potent than pirenzepine - a dose response and comparative secretorystudyin manw LONDONG, VLONDONG, A MEIERL, AND U VODERHOLLER ....8................................ 888Case reports: Acute ischaemic colitis in a female long distance runner M HI F-R, RIEPOND, A HANY, H SUILSER,0 KEHL,AND KJAGER ........................................................................... 896Emphysematous gastritis after acute pancreatitis L I BIOODWORTH, P I STIVINS, R F BURY, J P ARM, ANDDJRAINFORD ................................................................................. 9((Cholestasis and liver failure with lambda-AL amyloidosis F KONIKOFF, C MOR, S S[FrRN, M SHAKILAI, J HALEVY,ANI)IFTHEODOR............903AN kHOD R .............................................................................................. 9)Clinical trial: Tripotassium dicitrato bismuthate (TDB) versus two different dosages of cimetidine in thetreatment of resistant duodenal ulcersG BIANCHI PORRO, F PARENTE, AND M LA.ZARONI .... ................. 907Correspondence. Books . ........................ 912

No.8 AUGUST

Leading article: Cancer after peptic ulcer surgery DC CARTER .......................................... 921Alimentary tract and pancreas: Increased risk of cancer at multiple sites after gastric surgery for peptic ulcerCPJCAYGIII, MJ HILI,CN HAILIL,J SKIRKHAM,ANDTCNORTHFIEID .......................................924Gastro-oesophagealreflux and the migratingmotorcomplex RCGI I,.J E KEIIOW, ANI) DAVID LWINGATE ...... 929Electrodes for 24 hour pH monitoring- a comparative study G M(cLAUCHILAN, J M RAWLINGS, M ILUCAS,RFMcCLOY,GPCREAN,ANDKLE McCOI ............................................................. 935Oesophageal manometry: how well does it predict oesophageal function C o H RUSS IL AND G WHELAN ....... 940H, antagonists in the treatment of reflux oesophagitis: can physiological studies predict the response'?DA F ROBER[SON,M A ALDERSLEY,H SHFEPHERD, R S LLOYD, ANDC L SMITH .................................. 946Small bowel resistances and the gastroduodenal brake N J PARR, J S GRIMF1-, J N BAXTER, M CRITCHILEY, ANDC R MACKIE ................................................................................... 950Involvement of alpha-I and alpha-2 adrenoceptors in the postlaparotomy intestinal motor disturbances in therat A SAGRADA, M J FARGEAS, AND I BUF NO .......................................................... 955Action of centrally mediated autonomic stimulation on human upper gastrointestinal transit: a comparativestudyoftwostimuliJ DO'BRIEN, DG IHOMPSON, w RBURNHAM,J HOLLY, AND EWAIKER . ..................... 96075Se HCAT test in the detection of bile acid malabsorption in functional diarrhoea and its correlation withsmall bowel tranSitG SCIARRETA, G FAGIOLI, A FURNO, G VICINI, CFCCHFI-Il, B GRIGOIO, A VI-RRI, AND P MAIAGUTI 970Phagocytesin cell suspensionsofhuman colon mucosa W BEEKEN, I NORI HWOOI), C BF LIVEAU,AND DGUMP 976Increased activity of digestive enzymes in ileal enterocytes adapting to proximal small bowel resectionMCHAVES, M WSMITH, ANDRC N WILI IAMSON ........................................................ 981HLA-DR expression, natural killer cells and IgE containing cells in the jejunal mucosa of coeliac childrenA ARATO, E SAVILAHTI, V-NI TAINIO, M Vl-RKASAI O, ANDT K EMOI A ........................................988Evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease M F KAGNOFF,YJ PAlERSON, PJ KUMAR, D D KASARDA, F RCARBONE, DrJ UNSWORTH, ANI) R K AUSIIN .......... ................ 995Increased arachidonic acid composition of phospholipids in colonic mucosa from patients with activeulcerativecolitisTNlsHlDA, H MIWA, ASHIGEMAISU, M YAMAMOFO, M IIDA, AND M FUJISHIMA .... .............. 1002Sulphasalazine induced seminal abnormalities in ulcerative colitis: resultsofmesalazine substitution S A RL FY,J LECARPENTIER, v MANI, M J GOODMAN, B K MANDAI,AND I.ATURNBERG ................................... 1008Local IgA subclass alterations in ulcerativecolitisand Crohn'sdisease of the colon KKE-iiAND P BRANDTZIAE( 1013Liver and biliary: Role of liver atrophy, hepatic resection and hepatocyte hyperplasia in the development ofportal hypertension in biliary disease N S HAIDJIS ANDr I H BLUMGAR'l ...................................... 1022Clinicaltrials: Single dose tetracycline in cholera MOHAMMAI) RAFIQUI, ISI AM ...... ....................... 1029Treatment of chronic constipation with cisapride and placebo S A MiILIER-L ISSNER AND IHE BAVARIANCONSIIPATIONSTUDY GROUP .................................................................. 1003Case reports: Oral clonidine for proctalgia fugax RAJAN SWAIN ......................................... 1039Pseudopolycythaemia and coeliac disease J R CRAMPION, M VTOBIN, AND R B M CONN 1ILI...... ............... 1041Progress report: Chronic portal systemic encephalopathy: update 1987 SHIll A SHF RILOCK ...... ............ 1043Immunohistochemical Cal9-9 in primary colonic polyps and polyps synchronous with colorectal cancerNHAFDHAL,ALONG,ITOBBIA, ACUIIEN, ANI) DPO'DONOGHUE ......... ................................ 1049Books ................................................................. 1056

Contents

No. 9 SEPTEMBER 1987Page

Leading article: Helping the mucosa make sense of macromolecules I BJARNASON AND T J PETERS .... ....... 1057Alimentary tract and pancreas: Passage of dietary antigens into the blood of children with coeliac disease.Quantification and size distribution of absorbed antigens S HUSBY, N FOGED, A H0ST, AND S-E SVEHAG .... .... 1062Improvement of abnormal lactulose/rhamnose permeability in active Crohn's disease of the small bowel byan elemental diet I R SANDERSON, P BOULTON, I MENZIES, AND J A WALKER-SMITH .......................... 1073Propionate absorption and metabolism in the rabbit hindgut M Y VERNAY ............................... 1077Effect of polymer coating on faecal recovery of ingested 5-amino salycylic acid in patients with ulcerativecolitiS H AL MARDINI, D C LINDSAY, C M DEIGHTON, AND CO RECORD ...................................... 1084Is the diarrhoea in ulcerative colitis related to impaired colonic salvage of carbohydrate? SS C RAO, N W READ,AND C D HOLDSWORTH .....................10................................................... 1090In vivo effects of orally administered prednisolone on prostaglandin and leucotriene production in ulcerativeCOlitiS K LAURITSEN, L STAiERK LAURSEN, K BUKHAVE, AND J RASK-MADSEN ................................. 1095Flow cytometric DNA analysis in longstanding ulcerative colitis: a method of prediction of dysplasia andcarcinoma development? R LOFBERG, B TRIBUKAIT, A OST, 0 BROMSTROM, AND H REICHARD ..... ............. 1100Neurotensin like immunoreactivity after intestinal resection in the rat P S OLSEN, J H PEDERSEN, S S POULSEN,Y YAMASHITA, AND P KIRKEGAARD ................ ................................................. 1107Effects of oral laxatives on colonic motor complexes in dogs M KARAUS, S K SARNA, H V AMMON, ANDM WIENBECK ................................................................................ 1112Acid suppression in duodenal ulcer: a meta-analysis to define optimal dosing with antisecretory drugsD B JONES, C W HOWDEN, D W BURGET, GD KERR, AND RH HUNT ......................................... 1120Origin of gastrin liberated by gastrin releasing peptide in man L LUNDELL, G LINDSTEDT, AND L OLBE .... .... 1128Multiple duodenal ulcer: natural history and pathophysiology w M HUI AND S K LAM ..... ................. 1134Endoscopic needle aspiration cytology: a new method for the diagnosis of upper gastrointestinal cancerCJ H INGOLDBY, M K MASON, AND R I HALL ............ .............................................. 1142Ambulatory 24 hour intraeosophageal pH-monitoring in the diagnosis of gastroesophageal reflux diseaseF JOHNSSON, B JOELSSON, AND P-E ISBERG . .......................................................... 1145Liver and biliary: Effect of Valsalva's manoeuvre and hyoscinbutylbromide on the pressure gradient acrossthe wall of oesophageal varices s W HOSKING, P ROBINSON, AND A G JOHNSON ............................. 1151Free radical generation by neutrophils: a potential mechanism of cellular injury in acute alcoholic hepatitisA J K WILLIAMS AND R E BARRY . ................................. ............................. 1157New techniques: Pressure measurement in oesophageal varices: preliminary report on a new non-invasivemethod PH GERTSCH AND J-J MEISTER ..................................... ... 1162Case reports: Effective intravenous cyclosporin therapy in a patient with severe Crohn's disease onparenteral nutrition B F ALLAM, JANET E TILLMAN, T J THOMSON, F T CROSSLING, AND LORNA M GILBERT .... ..... 1166Spontaneous haemoperitoneum from rupture of a primary hepatic adenoma in an adult man P D McINERNEY,M G VAN DESSEL, AND D A BERSTOCK ....... ..................... 1170Neurofibromatosis and small bowel adenocarcinoma: an unrecognised association T J JONES ANDT L MARSHALL ............................................................................... 1173Progress report: Technical aspects of intraluminal pH-metry in man: current status and recommendationsC EMDE, A GARNER, AND A L BLUM . ................................................................. 1177Correspondence. News ........................................................................ 1189

No. 10 OCTOBER 1987Leading article: Extra hepatic portal venous obstruction D R TRIGER ............ ....................... 1193Liver and biliary: Spontaneous (natural) splenoadrenorenal shunts in extrahepatic portal venousobstruction: a series of 20 cases J B DILAWARI ANDY K CHAWLA . .................................... 1198Temporary blood flow with degradable starch microspheres (DSM) for liver metastases in a rat modelA D S FLOWERDEW, H K RICHARDS, AND I TAYLOR ..................................................... 1201Alimentary tract and pancreas: Demonstration of pepsinogen C in human islets P B SZECSI, H HALGREEN,S S POULSEN, C K AXELSSON, M D DAMKLER-NIELSEN, T KJAER, AND B FOLTMANN ............................. 1208In vitro stimulation enzyme discharge by calcium P LAYER, J HOTZ, L CHERIAN, AND H GOEBELL .... .......... 1215Short chain fatty acids in human large intestine, portal, hepatic and venous blood J H CUMMINGS, E W POMARE,W J BRANCH, C P E NAYLOR, AND G T MACFARLANE ..................................................... 1221Pressure and prolapse - the cause of solitary rectal ulceration N R WILLIAMS, J H M HOLMFIELD, ANDJ F B MORRISON .................... . .................... .... 1228Anal canal pressure profile: a reappraisal as determined by rapid pullthrough technique s M McHUGH ANDN E DIAMANT ................................................................................. 1234

Contents

PagePreservation of faceal continence during rises in intra-abdominal pressure: is there a role for the flap valve?J J BANNISTER, C GIBBONS, AND N W READ ........... ................................................ 1242Effect of stool size and consistency on defecation J J BANNISTER, P DAVISON, J M TIMMS, C GIBBONS,AND N W READ ................................................................................ 1246Alterations of humoral, cell mediated, and antibody dependent cell mediated cytotoxic responses duringthe course of amoebic infection in guinea pigs v K VINAYAK, A SAXENA, AND A K MALIK ..... ................ 1251Psychosocial sequelae of stoma surgery for inflammatory bowel disease in childhood B LASK, J JENKINS,L NABARRO, AND I BOOTH . ........................................................................ 1257Prognosis of chronic ulcerative colitis in a community c M STONNINGTON, S F PHILLIPS, A R ZINSMEISTER,AND L J MELTON III ............................................................................. 1261Functional characteristics of intraepithelial lymphocytes from mouse small intestine III. Inability ofintraepithelial lymphocytes to induce a systemic graft-versus-host reaction is because of failure to migrate invivo MARIA E BACA, A MCI MOWAT, SHEILA MACKENZIE, AND DELPHINE M V PARROT ............... ......... 1267Delayed mouth-caecum transit of a lactulose labelled liquid test meal in patients with steatorrhoea causedby partially treated coelic disease R C SPILLER, Y C LEE, C EDGE, D N L RALPHS, J S STEWART, S R BLOOM, ANDD B A SILK ................................................................................. 1275Organ culture of rabbit ileum as a model for the investigation of the mechanism of intestinal damage byenteropathogenic Escherichia coli R M BAIT, C A HART, I McLEAN, AND J R SAUNDERS ..... .................. 1283Effect of luminal pH on the output of bicarbonate and PGE2 by the normal human stomach J R CRAMPITON,LCGIBBONS, ANDWD REES . ..................................................................... 1291Case reports: Carcinoid tumour of the ampulla of Vater presenting as acute pancreatitis J M DIXON,RW CHAPMAN, AND A R BERRY . .................................................................... 1296A mixed endocrine adrenal tumour causing steatorrhoea P THESLEFF, C BENONI, H MARTENSSON, A NILSONN,FSUNDLER, AND B AKESSON . ................................................................... 1298AIDS related Kaposi's sarcoma presenting as ulcerative colitis and complicated by toxic megacolonB A BIGGS, S M CROWE, C R LUCAS, M RALSTON, I LTHOMPSON, AND KJ HARDY ............................... 1302Progress report: Psychological factors in the irritable bowel syndrome FRANCIS CREED AND ELSPETH GUTHRIE 1307Correspondence. Books. News . ................................................................. 1319

No. 11 NOVEMBER 1987

Leading article: What is the cause of the carcinoid flush? D G GRAHAME-SMITH ........................... 1413Alimentary tract and pancreas: Bradykinin in carcinoid syndrome J GUSTAFSEN, S BOESBY, F NIELSEN, ANDJ GIESE ...................................................................................... 1417Lymphokine activated killer (LAK) cells in patients with gastrointestinal cancer J R T MONSON, CW RAMSDEN,

GILES, BRENNAN, AND GUILLOU ............................................................ 1420Pathogenesis of the impaired gall bladder contraction of coeliac disease A M BROWN, M J BRADSHAW,R RICHARDSON, J G WHEELER, AND R F HARVEY .................................... ................. 1426Segmental necrotising enterocolitis: pathological and clinical features of 22 cases in Bangladesh T BUTLER,B DAHMS, K LINDPAINTNER, M ISLAM, M A K AZAD, AND P ANTON .................. .. ..................... 1433Investigation of intestine function during acute viral hepatitis using combined sugar oral loads G PARRILLI,R CUOMO, G NARDONE, G MAIO, C M IZZO, AND G BUDILLON ............................................. 1439Increased phospholipase A2 and decreased lysophospholipase activity in the small intestinal mucosaafter ischaemia and revascularisation T OTAMIRI, L FRANZEN, D LINDMARK, AND C TAGESSON ....... ......... 1445Relationship between duodenal bile acids and colorectal neoplasia R J MOOREHEAD, G R CAMPBELL,J D DONALDSON, AND S T D McKELVEY .............................. ................................ 1454Absence of complement fixing antibodies against lipopolysaccharides from Escherichia coli in a subgroup ofpatients with Crohn's disease M ZEITZ, U HOPF, B WUST, C GALANOS, B MOLLER, T J LAWLEY, AND E 0 RIECKEN ... 1460An epidemic of pseudomembranous colitis: importance of person to person spread N P M NOLAN, C P KELLY,J F H HUMPHREYS, C COONEY, R O'CONNOR, T N WALSH, D G WEIR, AND D S O'BRIAIN .......................... 1467Influence of olsalazine on gastrointestinal transit in ulcerative colitis s SC RAO, N W READ, AND C D HOLDSWORTH 1474Relationship between spontaneous non-propagating pressure activity in the oesophagus and acid gastro-oesophageal reflux in pathological and non-pathological refluxers S KRUSE-ANDERSEN, L WALLIN, ANDT MADSEN ................................................................................. 1478Patterns of acid reflux in complicated oesophagitis D ROBERTSON, M ALDERSLEY, H SHEPHERD, AND CL SMITH .. 1484Screening by colonoscopy for colonic epithelial dysplasia in inflammatory bowel disease A P MANNING,OR BULGIM, M F DIXON, AND AT R AXON .............. .............................................. 1489Liver and biliary: Biliary lipid metabolism in chronic pancreatitis: influence of steatorrhoea K EINARSSON,B ANGELIN, AND C JOHANSSON ................................................................... 1495

Contents

PagePostcholecystectomy symptoms. A prospective study of gall stone patients before and two years after surgeryEROS AND DZAMBON ................. ................................ 1500Clinical trials: Combined anti-muscarinic and H2 receptor blockade in the healing of refractory duodenalulcer. A double blind study K D BARDHAN, MARY THOMPSON, K BOSE, R F C HINCHLIFFE, J CROWE, D G WEIR,C McCARTHY, J WALTERS, T J THOMSON, M H THOMPSON, J E GAIT, C KING, AND D PRUDHAM ....5................. 505Double blind study of ispaghula in irritable bowel syndrome ALISON PRIOR AND PJ WHORWELL .... .......... 1510Case reports: Isolation of Chlamydia trachomatis from the liver of a patient with prolonged fever M DAN,LDJ TYRRELL,ANDG GOLDSAND . .................................................................. 1514Familial giant hypertrophicgastritis (Menetrier's disease) B LARSEN, U TARP, AND E KRISTENSEN .... ........ 1517Achalasia like disorder of the oesophagus in von Recklinghausen's neurofibromatosis P N FOSTER, MARGARETSTEWART, J S LOWE, AND MICHAEL ATKINSON .................................. 1522Occasional report: Results of a questionnaire concerning the staffing and administration of endoscopy inEngland and Wales A T R AXON, P M BOTTRILL, D CAMPBELL (ON BEHALF OF THE BSG WORKING PARTY ON THESTAFFING OF ENDOSCOPY UNITS) . .................................................................. 1527Progress report: Cystic fibrosis- a gastroenterological cornucopia P L ZENTLER-MUNRO .... ............... 1531Correspondence. Books. News . ................................................................ 1548

No. 12 DECEMBER 1987

Leading article: Mucus bicarbonate barrier- shield or sieve w 0 W REES ............................... 1553Alimentary tract and pancreas: De-Nol stimulates gastric and duodenal alkaline secretion through prosta-glandin dependent mechanism S J KONTUREK, J BILSKI, N KWIECIEN, W OBTULOWICZ, B KOPP, AND J OLEKSY .... 1557Effect of the diaphragmatic contraction on lower oesophageal sphincter pressure in man R K MITrAL,D F ROCHESTER, AND RW McCALLUM ...... 1564Effects of partial truncal vagotomy on intragastric pressure responses to vagal stimulation and gastricdistension in ferrets S A ASALA, A J BOWER, AND I N C LAWES ........................................... 1569Healthy controls have as much bile reflux as gastric ulcer patients N E SCHINDLBECK, C HEINRICH, F STELLAARD,G PAUMGARTNER, AND S A MULLER-LISSNER ........... .............................................. 1577Effect of food consistency on gastric emptying in man L A HOUGHTON, F HICKSON, AND N W READ .... ........ 1584Local immunoglobulin production is different in gastritis associated with dermatitis herpetiformis andsimple gastritis K VALNES, P BRANDTZAEG, K ELGJO, R STAVE, K BAKLIEN, AND 0 FAUSA .... .................. 1589Coeliac disease. among children in Kuwait: difficulties in diagnosis and management F A KHUFFASH,M H BARAKAT, A A S14ALTOUT, S S FARWANA, M S ADNANI, AND M FTUNGEKAR ............................... 1595Psychiatric illness in patients with inflammatory bowel disease H ANDREWS, P BARCZAK, AND R N ALLAN ...... 1600Participation of prostaglandin E2 in the purinergic neurotransmission of gut J T CHENG AND K SHINOZUKA .... 1605Reduction of colonic motility by intravenous nicardipine in irritable bowel syndrome ALISON PRIOR, S R HARRIS,AND PJ WHORWELL ........... 1609Colonic myoelectrical activity in IBS painless diarrhoea J FREXINOS, J FIORAMONTI, AND L BUENO .... ........ 1613Immunological study of the rectal mucosa of men with and without human immunodeficiency virus infectionP E BISHOP, A McMILLAN, AND H M GILMOUR ............ ............................................. 1619Significance of a fall in serum CEA concentration in patients treated with cytotoxic chemotherapy fordisseminated colorectal cancer T G ALLEN-MERSH, N KEMENY, D NIEDZWIECKI, B SHURGOT, AND J M DALY ...... 1625Liver and biliary: Ulcerative colitis in the Jewish population in Southern Israel 1961-1985: epidemiologicaland clinical study H S ODES, D FRASER, AND J KRAWIEC ................................................ 1630Hepatic intestinal uptake and release of catecholamines in alcoholic cirrhosis. Evidence of enhanced hepaticintestinal sympathetic nervous activity J H HENRIKSEN, H RING-LARSEN, AND N JUEL CHRISTENSEN ..... ....... 1637Renal function in fulminant hepatic failure: haemodynamics and renal prostaglandins F GUARNER,R D HUGHES, A ES GIMSON, AND ROGER WILLIAMS ......... ..................... ...... 1643Effects of recombinant interleukin 2 on hepatitis B e antigen positive chronic hepatitis M ONJI, H KONDOH,N HORIIKE, S YAMAGUCHI, Y OGAWA, I KUMON, AND YOHTA ............................................ 1648Case reports: Cholangitis in the acquired immunodeficiency syndrome: report of two cases and review of theliterature D ROULOT, D VALLA, F BRUN-VEZINET, M-A REY, F CLAVEL, C DEGOTT, J GUILLAN, J VERDURON, B RUEFF,AND J-P BENHAMOU ............................................................................. 1653Multiple listerial liver abscesses D JENKINS, J E RICHARDS, Y REES, AND A C B WICKS ...... .................. 1661Neuromuscular and vascular hamartoma of the small intestine: is it Crohn's disease? N A SHEPHERD ANDJ R JASS ....................................... 1663Crohn's disease with respiratory tract involvement M LEMANN, B MESSING, F D AGAY, AND R MODIGLIANI ...... 1669Clinical and ultrastructural studies in duodenal pseudomelanosis i Y KANG, A Y T WU, J L S CHIA, A WEE,I H SUTHERLAND, AND R HORI . .................................................................... 1673

Contents

PageOccasional report: Report of a working party on the staffing of endoscopy units ......................... 1682Correspondence. Books. News . ................................................................ 1686General index to volume 28 . ................................................................... 1693Index to abstracts ............................................................................. 1716