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 Tablet Asetosal 200 mg

Kelompok 3D

Spektrum serapan isobastik asetosal dalam air (270.70 nm)

Konsentrasi (ug/mL) Serapan (A)

0 0.3!7

"0 0.!2

#00 0.$$!

#20 0."!

#!0 0.7

#0 0.""2

200 #.072

!0 0 "0 #00 #20 #!0 #0 #"0 200 220

0

0.2

0.!

0.

0."

#

#.2

%(&) ' 0.00$#"7$!#& 0.0!3!0#33

*+ ' 0."32#!"$3

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KONSENTRASI HASIL DISOLUSI

,aktu (menit) A - A$ 0.02$ 0.02# 0.0#$ 0.0!3!

#0 0.033 0.03! 0.02" 0.0!3!

#$ 0.03" 0.0$3 0.0!$ 0.0!3!

30 0.0$ 0.#02 0.0"3 0.0!3!

!$ 0.#0 0.#3 0.## 0.0!3!

7$ 0.#!# 0.27 0.#7 0.0!3!

0 0.#$7 0.27 0.22$ 0.0!3!

#0$ 0.#77 0.33! 0.2$2 0.0!3!

#20 0.#2 0.37$ 0.27 0.0!3!

#$0 0.223 0.!#3 0.32$ 0.0!3!#"0 0.2$# 0.!"# 0.33 0.0!3!

2#0 0.2 0.$# 0.!#$ 0.0!3!

2!0 0.30$ 0.$ 0.!$7 0.0!3!

270 0.327 0.#2 0.!" 0.0!3!

300 0.3!$ 0.! 0.$2$ 0.0!3!

330 0.37 0.3 0.$2 0.0!3!

30 0.37! 0. 0.$2 0.0!3!

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PERHIT

A B

- A-S KADA* A - A-S0.00$2 0.02$   -3.538461538 0.0!3! 0.00$2 0.02#

0.00$2 0.033   -2 0.0!3! 0.00$2 0.03!

0.00$2 0.03"   -1.038461538 0.0!3! 0.00$2 0.0$3

0.00$2 0.0$   4.1538461538 0.0!3! 0.00$2 0.#02

0.00$2 0.#0   12.038461538 0.0!3! 0.00$2 0.#3

0.00$2 0.#!#   18.769230769 0.0!3! 0.00$2 0.27

0.00$2 0.#$7   21.846153846 0.0!3! 0.00$2 0.27

0.00$2 0.#77   25.692307692 0.0!3! 0.00$2 0.33!

0.00$2 0.#2   28.576923077 0.0!3! 0.00$2 0.37$

0.00$2 0.223  34.538461538

0.0!3! 0.00$2 0.!#30.00$2 0.2$#   39.923076923 0.0!3! 0.00$2 0.!"#

0.00$2 0.2   47.423076923 0.0!3! 0.00$2 0.$#

0.00$2 0.30$   50.307692308 0.0!3! 0.00$2 0.$

0.00$2 0.327   54.538461538 0.0!3! 0.00$2 0.#2

0.00$2 0.3!$   58 0.0!3! 0.00$2 0.!

0.00$2 0.37   62.807692308 0.0!3! 0.00$2 0.3

0.00$2 0.37!   63.576923077 0.0!3! 0.00$2 0.

 

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NGAN KADAR

C

KADA* A - A-S KADA*-4.3076923077 0.0!3! 0.00$2 0.0#$   -5.461538462

-1.8076923077 0.0!3! 0.00$2 0.02"   -2.961538462

1.8461538462 0.0!3! 0.00$2 0.0!$   0.3076923077

11.269230769 0.0!3! 0.00$2 0.0"3   7.6153846154

23 0.0!3! 0.00$2 0.##   14.538461538

43 0.0!3! 0.00$2 0.#7   29.538461538

48.769230769 0.0!3! 0.00$2 0.22$   34.923076923

55.884615385 0.0!3! 0.00$2 0.2$2   40.115384615

63.769230769 0.0!3! 0.00$2 0.27   45.307692308

71.0769230770.0!3! 0.00$2 0.32$

  54.153846154

84.153846154 0.0!3! 0.00$2 0.33   61.461538462

90.884615385 0.0!3! 0.00$2 0.!#$   71.461538462

99.346153846 0.0!3! 0.00$2 0.!$7   79.538461538

109.34615385 0.0!3! 0.00$2 0.!"   85.692307692

114.73076923 0.0!3! 0.00$2 0.$2$   92.615384615

119.15384615 0.0!3! 0.00$2 0.$2   99.730769231

120.30769231 0.0!3! 0.00$2 0.$2   105.5

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b a

' 0.00$2 0.0!3! TA-1 A

,aktuAbsorban

Konsentrasi Kadar aktor

(menit) (mg) Koreksi

$ 0.02$ 43.$! 43.$!

#0 0.033 42.00 42.00

#$ 0.03" 4#.0! 4#.0!30 0.0$ !.#$ !.#$

!$ 0.#0 #2.0! #2.0! 0.02

0 0.## #3. #3. 0.0

7$ 0.#!# #".77 #".77 0.07

0 0.#$7 2#."$ 2#."$ 0.0

#0$ 0.#77 2$. 2$. 0.##

#20 0.#2 2".$" 2".$" 0.#3

#$0 0.223 3!.$! 3!.$! 0.#!

#"0 0.2$# 3.2 3.2 0.#7

2#0 0.2 !7.!2 !7.!2 0.202!0 0.30$ $0.3# $0.3# 0.2!

270 0.327 $!.$! $!.$! 0.2$

300 0.3!$ $".00 $".00 0.27

330 0.37 2."# 2."# 0.2

30 0.37! 3.$" 3.$" 0.32

b a

' 0.00$2 0.0!3! TA-1 -

,aktuAbsorban

Konsentrasi Kadar aktor

(menit) (mg) Koreksi

$ 0.02# 4!.3# 4!.3#

#0 0.03! 4#."# 4#."#

#$ 0.0$3 #."$ #."$

30 0.#02 ##.27 ##.27 0.0#

!$ 0.#3 23.00 23.00 0.0

0 0.2#$ 33.00 33.00 0.#2

7$ 0.27 !3.00 !3.00 0.#7

0 0.27 !".77 !".77 0.22

#0$ 0.33! $$."" $$."" 0.2!

#20 0.37$ 3.77 3.77 0.2"

#$0 0.!#3 7#.0" 7#.0" 0.32

#"0 0.!"# "!.#$ "!.#$ 0.3

2#0 0.$# 0."" 0."" 0.!2

2!0 0.$ .3$ .3$ 0.!

270 0.#2 #0.3$ #0.3$ 0.$0

300 0.! ##!.73 ##!.73 0.$$

330 0.3 ##.#$ ##.#$ 0.$"

30 0. #20.3# #20.3# 0.0

(5g/ml)

(5g/ml)

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b a

' 0.00$2 0.0!3! TA-1

,aktuAbsorban

Konsentrasi Kadar aktor

(menit) (mg) Koreksi

$ 0.0#$ 4$.! 4$.!

#0 0.02" 42. 42.#$ 0.0!$ 0.3# 0.3#

30 0.0"3 7.2 7.2 0.00

!$ 0.## #!.$! #!.$! 0.0!

0 0.#$3 2#.0" 2#.0" 0.07

7$ 0.#7 2.$! 2.$! 0.##

0 0.22$ 3!.2 3!.2 0.#$

#0$ 0.2$2 !0.#2 !0.#2 0.#"

#20 0.27 !$.3# !$.3# 0.20

#$0 0.32$ $!.#$ $!.#$ 0.23

#"0 0.33 #.! #.! 0.272#0 0.!#$ 7#.! 7#.! 0.3#

2!0 0.!$7 7.$! 7.$! 0.3

270 0.!" "$. "$. 0.!0

300 0.$2$ 2.2 2.2 0.!3

330 0.$2 .73 .73 0.!7

30 0.$2 #0$.$0 #0$.$0 0.$0

(5g/ml)

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 Kadar setela6 8

,aktu  

ditamba6 %aktor koreksi (menit) A

$

#0

#$!.#$ 2.0 30 2.0

#2.0 7.$! !$ 7.$!

#!.02 ".7 0 ".7

#"."! ##.77 7$ ##.77

2#.! #3.7# 0 #3.7#

2$."0 #.#3 #0$ #.#3

2".7# #7.! #20 #7.!

3!." 2#." #$0 2#."

!0.#0 2$.0 #"0 2$.0

!7.2 2.7 2#0 2.7$0.$$ 3#.$ 2!0 3#.$

$!.7 3!.2! 270 3!.2!

$".27 3.!2 300 3.!2

3.#0 3.!! 330 3.!!

3." 3.3 30 3.3

 Kadar setela6 8

ditamba6 %aktor koreksi

#."$ #.#$

##.2" 7.0$

23.0 #!.!#

33.#2 20.70

!3.#7 2."

!". 30.2

$.#3 3$.0"

!.0$ !0.03

7#.!0 !!.2

"!.$# $2."2

#.3# $7.07

."0 2.3"

#0."$ ".$

##$.2" 72.0$

##.73 7!."3

#20.# 7$.$7

0 $0 #00 #$0

0

#0

20

30

!0

$0

0

70

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 Kadar setela6 8

ditamba6 %aktor koreksi

0.3# 0.#

7.2 !.7

#!.$" .##

2#.#$ #3.22

2.! #".$3

3$.07 2#.2

!0.2 2$.#"

!$.$# 2".!!

$!.3" 33.

#.73 3".$"7#.77 !!."

7.0 !.!

".0 $3."#

3.0$ $".#$

#00.20 2.2

#0.00 .2$

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8 *ata4rata

- 8

#.#$ 0.# 0.77.0$ !.7 !."0

#!.!# .## #0.3$

20.70 #3.22 #!.23

2." #".$3 #.0

30.2 2#.2 22.0"

3$.0" 2$.#" 2$.!

!0.03 2".!! 2"."#

!!.2 33. 33.!3

$2."2 3".$" 3"."2

$7.07 !!." !3.02.3" !.! !7.7

".$ $3."# $2.2!

72.0$ $".#$ $$.$!

7!."3 2.2 $".

7$.$7 .2$ 0.$"

200 2$0 300 3$0 !00

olumn 1

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