07_Evaluasi Kestabilan Suspensi
-
Upload
edgarjunior014 -
Category
Documents
-
view
220 -
download
0
Transcript of 07_Evaluasi Kestabilan Suspensi
-
8/12/2019 07_Evaluasi Kestabilan Suspensi
1/13
EVALUASI KESTABILANEVALUASI KESTABILAN
SUSPENSISUSPENSI
-
8/12/2019 07_Evaluasi Kestabilan Suspensi
2/13
MetodeMetode EvaluasiEvaluasi SuspensiSuspensi
1. Volume1. Volume SedimentasiSedimentasi ( F )( F )
F = HF = HUU/H/H00 x 100 %x 100 %HargaHarga F = > 1 1 pressure in particle 2
S(a)1 > S(a)2
-
8/12/2019 07_Evaluasi Kestabilan Suspensi
11/13
Ostwald ripening (2)
L
(a)1
L
(a)2
x(a)1 x(a)2S(a)1 S(a)2
S(a)1 > S(a)2
L(a)1 > L(a)2
L(a) + RT ln x(a)1 > L
(a) + RT ln x(a)2
At equilibrium: S(a)1 = L(a)1 en S(a)2 = L(a)2
x(a)1> x(a)2
-
8/12/2019 07_Evaluasi Kestabilan Suspensi
12/13
Packaging and Storage of Suspensions:Packaging and Storage of Suspensions:
1) Should be packaged in wide mouth1) Should be packaged in wide mouth
containers having adequate air space abovecontainers having adequate air space abovethe liquid.the liquid.
2) Should be stored in tight containers2) Should be stored in tight containers
protected from: freezing and excessiveprotected from: freezing and excessiveheat & lightheat & light
3) Label:3) Label: "Shake Before Use""Shake Before Use" to ensureto ensure
uniform distribution of solid particles anduniform distribution of solid particles andthereby uniform and proper dosage.thereby uniform and proper dosage.
-
8/12/2019 07_Evaluasi Kestabilan Suspensi
13/13
ASA
SA
SA