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Transcript of The therapeutic alliance and its relationship to alcoholism treatment participation and outcome
Jouraal of Consulting and Clinical Psychology1997. Vol. 65, No. 4, 388-598
Copyright 1997 by the American Psychological Association, Inc.0022-006)09743.00
The Therapeutic Alliance and Its Relationship to AlcoholismTreatment Participation and Outcome
Gerard J. ConnorsResearch Institute on Addictions
Kathleen M. CarrollYale University School of Medicine
Carlo C. DiClementeUniversity of Maryland—Baltimore County
Richard LongabaughBrown University
Dennis M. DonovanUniversity of Washington
The relationship between the therapeutic alliance and treatment participation and drinking outcomes
during and after treatment was evaluated among alcoholic outpatient and aftercare clients. In the
outpatient sample, ratings of the working alliance, whether provided by the client or therapist, were
significant predictors of treatment participation and drinking behavior during the treatment and 12-
month posttreatment periods, after a variety of other sources of variance were controlled. Ratings
of the alliance by the aftercare clients did not predict treatment participation or drinking outcomes.
Therapists ratings of the alliance in the aftercare sample predicted only percentage of days abstinent
during treatment and follow-up. The results document the independent contribution of the therapeutic
alliance to treatment participation and outcomes among alcoholic outpatients.
Research conducted over the recent decades has supported
the proposition that psychotherapy process variables are related
to treatment outcomes (Orlinsky, Grawe, & Parks, 1994). An
important focus of these empirical efforts has been the nature
and quality of the therapeutic (or working) alliance and its
relationship to treatment outcome. Although defined in a number
of ways over the years, most definitions of the therapeutic alli-
ance overlap in emphasizing a collaborative relationship be-
tween the client and therapist that consists of an emotional bond
and a shared presumption regarding the tasks and goals of the
treatment endeavor (e.g., Bordin, 1979; Greenson, 1967).
Research on the therapeutic alliance has been systematic and
Gerard J. Connors, Research Institute on Addictions, Buffalo, New
York; Kathleen M. Carroll, Substance Abuse Center, Yale University
School of Medicine; Carlo C. DiClemente, Department of Psychology,
University of Maryland—Baltimore County; Richard Longabaugh, Cen-
ter for Alcohol and Addiction Studies, Brown University; Dennis M.
Donovan, Alcohol and Drug Abuse Institute, and Department of Psychia-
try and Behavioral Sciences, University of Washington.
This research was supported by a series of grants from the National
Institute on Alcohol Abuse and Alcoholism. We gratefully acknowledge
the collaboration of the Project MATCH Research Group and especially
our fellow members of the Project MATCH Process Committee (Ned
Cooney, Ronald Kadden, William Miller, Philip Wirtz, and Allen
Zweben) in this research. We give special thanks to Kurt H. Dermen
and James R. Koutsky for their major contributions to the preparation
of this article.
Correspondence concerning this article should be addressed to Gerard
J. Connors, Research Institute on Addictions, 1021 Main Street, Buffalo,
New York 14203.
productive. The research to date, first and foremost, has reflected
an appreciation of the need to develop and evaluate tools for
measuring the therapeutic alliance (Horvath, 1994; Tichenor &
Hill, 1989). Subsequent research has provided several reason-
ably robust indications regarding the therapeutic alliance. Per-
haps the most important finding is that a positive therapeutic
relationship predicts treatment outcome. In reviewing this litera-
ture, Horvath and Symonds (1991) found a moderate but consis-
tent positive relationship between the therapeutic alliance and
outcome. The relationship was not related to the study sample
size or the length of treatment.
It also appears that ratings of the therapeutic alliance at early
stages of treatment are more predictive of outcome than are
ratings taken later in the treatment process (Gomes-Schwartz,
1978; Hartley & Strupp, 1983; Luborsky, Crits-Christoph, Alex-
ander, Margolis, & Cohen, 1983; Luborsky, McLellan, Woody,
O'Brien, & Auerbach, 1985). Furthermore, ratings of the alli-
ance provided by the client have been stronger predictors of
treatment outcome than ratings provided by the therapists (Hor-
vath, 1994; Horvath & Symonds, 1991). Finally, the available
research suggests that the relationship of the therapeutic alliance
to outcome is evident across therapeutic modalities. Horvath
and Symonds (1991) investigated this question in their review
and found that the relationship between alliance and outcome
appears robust across several types of psychotherapy (e.g., psy-
chodynamic, cognitive, eclectic).
There are limitations in the research accumulated to date on
the therapeutic alliance. First, the majority of research has been
conducted using relatively small sample sizes. The meta-analysis
reported by Horvath and Symonds (1991) included 20 studies
588
THERAPEUTIC ALLIANCE IN ALCOHOLISM TREATMENT 589
with an average sample size of 49 (range 8-144). In a more
recent study, a larger sample size of 225 was included (Krupnick
et al., 1996). Second, there has been variability in the extent to
which the treatments studied have been standardized, introduc-
ing a potential confound to the interpretation of results. Third,
past studies on therapeutic alliance often have not controlled
for client and therapist variables that might predict outcomes
independent of the therapeutic alliance.
The present report was designed to build on and extend past
work on the therapeutic alliance. The data were gathered as part
of Project MATCH (Matching Alcoholism Treatments to Client
Heterogeneity), a national multisite study of the matching of
patients to alcoholism treatments (Project MATCH Research
Group, 1993). Strengths of this study in the context of evaluat-
ing therapeutic alliance were the use of three highly distinguish-
able standardized treatments, the use of a large group of thera-
pists (N - 80) trained and certified to administer the respective
treatments, a large clinical sample (N = 1,726), the collection
of data at sites located across the country, and extensive assess-
ments before, during, and after treatment, including therapist
and client ratings of the treatment process.
The specific focus of this report is on the contribution of
the therapeutic alliance in alcoholism treatment to treatment
participation (weeks in treatment), drinking during treatment,
and posttreatment drinking. On the basis of past research, it was
expected that the therapeutic alliance, as rated by both the client
and therapist, would be linearly related to treatment participation
and positive drinking-related outcomes. It was further expected
that client ratings would be stronger predictors than therapist
ratings and that the predictive capability of the client and thera-
pist ratings would operate across the three treatments and across
treatment sites included in the study. Finally, the analysis plan
included procedures to control for the potentially confounding
influence of client characteristics, therapist characteristics, and
client pretreatment drinking history variables.
Method
Overview of Project MATCH
Project MATCH is a national multisite clinical trial designed to evalu-
ate hypotheses relating to patient-treatment matching. Two independent
but parallel matching studies were conducted, one with clients recruited
from outpatient settings (n = 952), the other with clients receiving
aftercare treatment after inpatient care (« = 774). After baseline assess-
ments, clients were randomly assigned to one of three 12-week treat-
ments: 12-step facilitation (TSF), cognitive-behavioral coping skills
treatment (CBT), or motivational enhancement therapy (MET). The
clients were followed at 3-month periods for the year after the treatment
period. At the 12-month posttreatment follow-up, 92% of the living
outpatients and 93% of the living aftercare clients were interviewed, hi
addition, several within-treatment process assessments were conducted.
The trial has been described in greater detail by the Project MATCH
Research Group (1993), and tests of the primary a priori matching
hypotheses have been reported (Project MATCH Research Group,
1997).
Participants
The present analyses included 698 outpatient (71% men) and 498
aftercare (80% men) clients. All met the criteria of the Diagnostic and
Statistical Manual of Mental Disorders (3rd ed., rev.; DSM-IH-R;
American Psychiatric Association, 1987) for a current diagnosis of alco-
hol abuse or dependence (for aftercare clients on the basis of drinking
during the period before admission to their inpatient or day hospital
admission), as assessed using the alcohol section of the Structured
Clinical Interview for the DSM-IH-R (SCID; Spitzer & Williams,
1985). The vast majority in each arm (> 95%) met the criteria for
alcohol dependence, as opposed to alcohol abuse. Descriptive informa-
tion is provided in Table 1 for clients in each arm of the trial.
The present sample represents 73% of the original population of
Project MATCH outpatients and 64% of the original population of Proj-
ect MATCH aftercare clients. The main reasons for deletion of cases
from the original population of 1,726 were missing Working Alliance
Inventory (WAI; Horvath & Greenberg, 1986) ratings (approximately
19%), mostly reflecting treatment dropouts, and missing therapist demo-
graphic information (approximately 11%). Comparisons of clients in
the present sample with those excluded for any reason (by outpatient
or aftercare arm and correcting alpha for tests within arm) revealed only
one difference in each arm. In both cases, the variable was marital
status. Chi-square tests showed in each case that clients included were
more often married, relative to those excluded.
Procedure
Every effort was taken to maintain comparability of procedures across
the two arms of the investigation (the outpatient and aftercare arms).
Outpatient clients were recruited from the community and from outpa-
tient treatment centers, whereas aftercare clients participated after com-
pletion of inpatient or intensive day hospital treatment. The clients were
recruited through nine clinical research units (CRUs) across the country
(five outpatient and four aftercare CRUs); outpatients were recruited
from five clinical sites, and aftercare clients were recruited from six
clinical sites (one outpatient CRU contributed to both outpatient and
aftercare recruitment and one aftercare CRU comprised two distinct
aftercare recruitment sites) associated with these CRUs.
Inclusion criteria for the outpatient sample were a current DSM-II1-
R (American Psychiatric Association, 1987) diagnosis of alcohol abuse
or dependence, alcohol as the principal drug of abuse, active drinking
during the 3 months before entrance to the study, a minimum age of 18,
and minimum sixth-grade reading level. Inclusion criteria for the after-
care arm were identical, except that symptoms of alcohol abuse or
dependence and requisite drinking behavior were assessed for the 3-
month period before the inpatient or day hospital admission, clients
completed a program of at least 7 days of inpatient or intensive day
hospital treatment (not simply detoxification), and clients were referred
for aftercare treatment by the inpatient or day hospital staff. Exclusion
criteria included a DSM-1I1—R diagnosis of current dependence on
sedative-hypnotic drugs, stimulants, cocaine, or opiates; any intrave-
nous drug use in the past 6 months; currently a danger to self or others;
probation-parole requirements that might interfere with protocol partici-
pation; acute psychosis or severe organic impairment; and current or
planned involvement in alternative treatments for alcohol problems other
than mat provided by Project MATCH (defined as greater than 6 hr of
nonstudy treatment, except for self-help groups, during the 3 months of
study treatment).
After an initial screen to evaluate the inclusion-exclusion criteria,
clients provided informed consent and participated in three intake ses-
sions that comprised personal interviews, computer-assisted assessment,
and completion of self-administered questionnaires (a description of the
full battery is provided by Connors et al., 1994). Where possible, an
interview was conducted with an individual familiar with the client's
drinking (i.e., a collateral). We assigned clients to treatment using a
computerized urn-balancing program designed to minimize differences
590 CONNORS, CARROLL, DlCLEMENTE, LONGABAUGH, AND DONOVAN
Table 1
Descriptive Information on Clients in the Outpatient and Aftercare Samples
Outpatient
Demographic
GenderAge (years)
MSD
Ethnicity (%)WhiteAfrican AmericanHispanic
OtherEducation (no. of years)
MSD
Relationship status (%)"Married
SingleEmployment (%)"
EmployedNot employed
Prior alcohol treatment (%)YesNo
Alcohol dependence symptoms0
MSD
Men
494 (71%)
39.210.7
814
131
13.52.2
4258
5842
46
54
5.91.9
Women
204 (29%)
39.311.3
787
113
13.61.9
2971
4060
3862
5.71.9
Total
698
39.310.8
805
132
13.52.1
3862
5347
4456
5.81.9
Men
396 (80%)
42.710.8
811432
13.12.1
4060
4951
6238
6.91.8
Aftercare
Women
102 (20%)
42.512.0
841321
13.22.1
2575
4456
5446
6.52.0
Total
498
42.611.0
821432
13.12.1
3763
4852
6040
6.81.9
a Married = married and living with spouse at least 1 year; single = all others. b Employed = employedfull time in same job continuously for past 6 months; not employed = all others. c Measured by theStructured Clinical Inventory for the DSM-HI-R for the 90-day baseline period (range = 1-9).
on variables such as critical demographic characteristics among clients
across the three study treatments in each arm (Stout, Wirtz, Carbonari, &
Del Boca, 1994).
After treatment assignment, treatment lasted 12 weeks. Therapy ses-
sions were videotaped to assure quality delivery of treatment and to
provide the data needed for a detailed investigation of treatment process
(Carroll, Kadden, Donovan, Zweben, & Rounsaville, 1994; DiClemente,
Carroll, Connors, & Kadden, 1994). In this regard, assessments in a
variety of process domains were incorporated into the protocol (DiCle-
mente et al,, 1994). Consistent with conceptual domains in psychother-
apy process research identified by Orlinsky and Howard (1986), these
included dose of treatment, within-session treatment interventions, the
therapeutic relationship, and extrasession activities. Directly relevant to
the purposes of the present report, the process assessment component
included ratings of the therapeutic alliance.
Follow-up assessments were scheduled at posttreatment and at follow-
ups 3, 6, 9, and 12 months after the end of treatment. The posttreatment,
6-month, and 12-month follow-ups were major evaluation points, involv-
ing the collection of blood and urine specimens and collateral interviews.
A more complete description of the trial protocol has been provided by
the Project MATCH Research Group (1993).
Treatments
Three treatment modalities were chosen for study in Project MATCH
because of their potential relevance to matching, the evidence for their
clinical efficacy, their distinctiveness from each other, feasibility of im-
plementation, and their application within existing treatment systems.
TSF was based on the concept of alcoholism as a spiritual and medical
disease with stated objectives of fostering acceptance of the disease
of alcoholism, developing a commitment to participate in Alcoholics
Anonymous, and beginning to work through the 12 steps. CBT was
grounded in social learning theory and on the view of drinking behavior
as functionally related to major problems in an individual's life, with
emphasis placed on overcoming skills deficits and increasing the ability
to cope with situations that commonly precipitate relapse. MET was
based on principles of motivational psychology and focused on produc-
ing internally motivated change. This treatment was not designed to guide
the client step by step through recovery; instead, it utilized motivational
strategies to mobilize the individual's own resources. TSF and CBT
both involved weekly treatment sessions, and MET consisted of four
sessions, occurring during the 1st, 2nd, 6th, and 12th weeks. The therapy
protocol for each modality is described in detailed treatment manuals
(Kadden et al., 1992; Miller, Zweben, DiClemente, & Rychtarik, 1992;
Nowinski, Baker, & Carroll, 1992).
A training protocol and standards for therapist certification and monitor-
ing were developed. Eighty therapists were certified to administer the
diree treatments in the trial. All sessions were videotaped, and supervisors
monitored 25% of all Project MATCH therapy sessions (over 2,500) to
ensure dierapist adherence to treatment manuals and to prevent therapist
variation from the protocol (Project MATCH Research Group, 1993).
Subsequent independent and masked videotape ratings have indicated the
discriminability and integrity of the treatments (Carroll et al., in press).
Therapists
Seventy-five therapists (40 in the outpatient study, 35 in the aftercare
study) for whom sufficient data were available are included in these
THERAPEUTIC ALLIANCE IN ALCOHOLISM TREATMENT 591
analyses (24 in TSF, 28 in CBT, and 23 in MET). The outpatient
therapists had a mean age of 39.3 years (SD = 7.8), and 65% were
women; the aftercare therapists averaged 37.7 years of age (SD = 7.1),
and 60% were women. The outpatient therapists treated an average of
17.3 clients (SD = 9.5), whereas the aftercare therapists treated an
average of 14.2 clients (5D = 7.8).
Measures
Client and therapist background characteristics. A variety of basic
background information (e.g., demographics, education, current marital
and employment status) was gathered from participants as part of the
initial screening and a formal diagnostic evaluation interview session.
All therapists completed a questionnaire that yielded comparable
information.
Treatment alliance and participation. The WAI (Horvath &
Greenberg, 1986) was used to assess the therapeutic alliance. The WAI
is a 36-item measure that consists of three subscales that address the
goals of therapy (Goal), agreement about the tasks of therapy (Task),
and the bond between the client and therapist (Bond). Ratings are made
on a 7-point Likert-type scale ranging from 1 (never) to 7 (always) on
the extent to which the respondent agrees with the statement, and a
global score is calculated by taking the sum of the 36 items (after
accounting for reverse-scored items). The WAI was selected for use in
this project for several reasons. First, the orientation of the WAI system
is eclectic and, thus, well-suited to the three treatments being evaluated.
Second, the psychometric properties of the WAI are well established,
with estimates of internal consistency and interrater reliability and valid-
ity at .85 and above on all subscales (Horvath & Greenberg, 1986;
Safran & Wallner, 1991; Tracey & Kokotovic, 1989). Third, there are
parallel forms of the WAI for rating by both the client and the therapist.
In this project, clients completed the WAI after the 2nd treatment session,
and therapists completed the measure after the 2nd, 6th, and 10th treat-
ment sessions (after Sessions 2 and 3 in the MET condition). Because
the WAI was completed by both the client and therapist after the second
session only, those ratings have been selected for use in this report.
There were isolated cases in which the client and therapist did not
complete the WAI at the second session. In these cases, several decision
rules were applied. First, if the WAI was completed at the first session,
these data were excluded (n = 3). Cases in which the WAI was com-
pleted at Session 4 or later (Session 3 in the case of the MET treatment)
similarly were deleted (n = 33). WAI data that were collected at Session
3 for TSF and CBT (which met weekly) were included and treated as
Session 2 reports (n = 28). Thus, all ratings of the therapeutic alliance
followed at least two treatment sessions but occurred no later than the
third treatment session in TSF and CBT and the second treatment session
in MET.
In the present report, the results are based on analyses incorporating
WAI total scores. This determination was made after evaluation of the
intercorrelations among the WAI subscales. The intercorrelations among
the subscales ranged from .69 to .91 (across client and therapist scores
and the two samples). The correlations between the subscales and the
total score ranged from .87 to .96. Further justification for the use of
the WAI total scores is provided by the structural analysis of the WM
reported by Tracey and Kokotovic (1989), who found support for the
use of the WAI to assess one general alliance dimension.
Drinking history and alcohol consumption. Several questionnaire
and interview measures were used to gather information on clients'
pretreatment drinking histories, including the alcohol section of the
SCID (Spitzer & Williams, 1985) and the Alcohol Use Inventory (AUI;
Wanberg, Horn, & Foster, 1977).
We obtained estimates of alcohol consumption for the 90-day pretreat-
ment period (for aftercare clients, the 90 days before inpatient or day
hospital treatment), the 12-week treatment period, and throughout the
12-month posttreatment follow-up period using the Form 90 (Miller,
1996). This interview procedure, which combined calendar memory
cues from the time-line follow-back methodology (Sobell & Sobell,
1992) and drinking pattern estimation procedures (Miller & Marian,
1984), provides estimates of alcohol consumption for each day of the
respective periods. A telephone interview version of the Form 90 and a
quick follow-up interview version were used for clients who were unable
to participate in in-person follow-up interviews and for uncooperative
clients.
Given the use of self-reports to assess drinking behavior, special atten-
tion was given to the evaluation of reliability and validity of these
measures. A comprehensive test-retest reliability study has shown the
Form 90 procedure to be highly reliable for the two main drinking
measures evaluated in Project MATCH (percentage of days abstinent
and drinks per drinking day; Tbnigan, Miller, & Brown, in press). Fur-
thermore, self-reports of drinking were examined in relation to gamma
glutamyl transpeptidase (GGTP) values at the 12-month posttreatment
follow-up (Project MATCH Research Group, 1997). Comparing clients
on the basis of their GGTP status (normal vs. abnormal) and gender on
percentage of days abstinent and drinks per drinking day during the 30-
day period preceding the blood draw showed that, in each study, self-
reported alcohol use was consistently higher for clients with abnormal
GGTP test results, as would be expected. Comparable indications were
provided in evaluating self-reports in relation to levels of carbohydrate-
deficient transferrin, another indicant of heavy alcohol consumption.
Taken together, the self-reports of drinking collected appear to have at
least acceptable levels of reliability and validity.
Analysis Plan
We evaluated the contribution of therapeutic alliance to treatment
participation and drinking behavior using a series of parallel hierarchical
multiple regression analyses, each comprising eight blocks of variables.
The eight blocks reflected, in order, client characteristics, therapist char-
acteristics, client drinking history, treatment site, treatment modality
received, the WAI total score, three two-way interactions, and a three-
way interaction.' The first five blocks served as covariates to eliminate
potential "third variable" explanations for the results. The variables
associated with each of the eight blocks are identified in Table 2. Cate-
gorical predictors were represented as sets of dummy-coded variables.
Five dependent variables were predicted, once each using the client
WAI total score data and once each using the therapist WAI total score
data, separately for each sample (outpatient and aftercare). The five
dependent variables were treatment participation, percentage of days
abstinent and drinks per drinking day during the treatment period, and
percentage of days abstinent and drinks per drinking day during the 12-
month posttreatment period. The percentage of days abstinent variable
was selected to provide an indication of drinking frequency, and the
drinks per drinking day was selected to provide a measure of drinking
severity or intensity. Treatment participation was operationalized as the
number of weeks involved in treatment during the 12-week treatment
period (i.e., number of weeks spanning the first and last treatment session
attended). This measure, rather than number of sessions or percentage
1 It may be argued that, because of its greater theoretical relevance,
the WAI X Treatment Modality interaction should be evaluated separately
and not within the block of three two-way interactions. Although includ-
ing this interaction within the block of two-way interactions is more
conservative, analyses entering the WAI X Treatment Modality interac-
tion term as a separate step (after the WAI score and before the block
of the remaining two-way interactions) also were performed. None of
the WW X Treatment Modality interactions were significant.
592 CONNORS, CARROLL, DlCLEMENTE, LONGABAUGH, AND DONOVAN
Table 2
Blocks and Associated Variables for the Hierarchical Multiple Regression Analyses
Block Variables
Client characteristics
Therapist characteristicsClient drinking history
Treatment siteTreatment modality
Working allianceTwo-way interactionsThree-way interaction
Gender, age, ethnicity (African American, Hispanic, White), education
Gender, age, educationPrevious alcoholism treatment (number of previous outpatient and inpatient treatment episodes), baseline percentage
of days abstinent (for 90-day pretreatment period before the client's last drink), baseline drinks per drinking day(for same pretreatment period), AUI (Wanberg, Horn, & Foster, 1977) Alcohol Involvement score, SCID
(Spitzer & Williams, 1985) alcohol dependence symptom count (range = 1-9) for the 90-day pretreatmentperiod, number of years since onset of problem drinking
Five outpatient sites and 6 aftercare sitesTSF, CBT, MET
WAI total score (for client or therapist, depending on the analyses, gathered after Treatment Session 2)WAI X Treatment Modality, WAI X Treatment Site, Treatment Modality X Treatment Site
WAI X Treatment Modality X Treatment Site
Note. Ethnicity, treatment site, and treatment modality were dummy coded. The 90-day pretreatment period ran backward from the day of the lastdrink before enrollment in the trial. The baseline period for the clients in the aftercare study was the period before entry to then* inpatient or dayhospital treatment episode. AUI = Alcohol Use Inventory; SCID = Structured Clinical Inventory for the DSM-III-R; TSF = 12-step facilitation;CBT = cognitive-behavioral coping skills therapy; MET = motivational enhancement therapy; WAI = Working Alliance Inventory.
of sessions attended, was chosen because it provided a more comparable
assessment of participation across these three treatments differing in the
number of sessions offered. Variables such as percentage of days absti-
nent and drinks per drinking day often depart from normality because
of skewness and floor-ceiling effects. In response, the percentage of
days abstinent variable was subjected to an arcsin transformation, and
the drinks per drinking day variable was subjected to a square root
transformation, in each case to improve the distribution. All clients had
nonmissing outcome scores for these drinking measures for at least
two thirds of the weeks or months, respectively, of the treatment and
posttreatment periods. The means and standard deviations for the WAI
raw scores and for the dependent variables are provided in Table 3, and
the correlations between the WAI therapist and client total scores with
the dependent variables, broken down by treatment condition, are pro-
vided in Table 4.
Results
Outpatient Study
The results of the multiple regression analyses for the client
and the therapist data, respectively, are shown in Table 5; the
results for the first five blocks of covariates are shown first,
followed by the WAI total scores and the interaction terms for
the client (top panel) and therapist (bottom panel) data.
The most consistent finding to emerge among the five blocks
of covariates in each set of analyses was the contribution of
client's drinking history, whereby variables reflecting greater
degrees of recent alcohol involvement predicted less treatment
participation and predicted lower percentage of days abstinent
and more drinks per drinking day during treatment and follow-
up. For example, treatment participation was negatively related
to AUI General Alcohol Involvement scale scores, and drinks
per drinking day during treatment and follow-up were predicted
by pretreatment drinks per drinking day and the number of
previous treatment experiences. Treatment modality was a pre-
dictor of three dependent variables in the client WAI analyses.2
Clients in CBT (M = 10.05) participated longer in treatment
than those in MET (M = 9.47) or TSF (M = 9.34). MET
clients (M = 79%) had a lower rate of percentage of days
abstinent during treatment than did the CBT (M = 84%) or
TSF (M = 83%) clients. The MET clients (M = 7.55) also had
more drinks per drinking day during follow-up than clients in
CBT (M = 6.89) or TSF (M = 6.60). Treatment modality
predicted only percentage of days abstinent when the therapist
WAI data were studied.
WAI total scores, whether provided by the client or therapist,
were significant predictors of each dependent variable. As pre-
dicted, ratings on the WAI were positively related to treatment
participation and percentage of days abstinent (during treatment
and posttreatment) and negatively related to drinks per drinking
day (during treatment and posttreatment). The ranges of /?2
change across the dependent variables were .008- .015 for client
WAI scores and .013- .034 for therapist WAI scores.
No interactions involving client WAI scores emerged. Two
interactions involved therapist WAI ratings, in each case op-
erating during the treatment period. Examination of the Treat-
ment Site X WAI therapist score interaction for treatment partici-
pation revealed a strong positive relationship between WAI
scores and weeks in treatment at two of the outpatient sites,
whereas, at the other sites, little relationship was observed. For
percentage of days abstinent during treatment, the Treatment Site
X WAI therapist score interaction generally revealed a positive
relationship between WAI scores and percentage of days absti-
nent, with the relationship more pronounced at three of the sites.
A third interaction, Treatment Site X Treatment Modality for
percentage of days abstinent during treatment, showed that, after
2 It is important to remember that the treatment main effects described
in this report need to be interpreted with caution, as the present sample
includes only clients attending two or more treatment sessions. Analyses
evaluating treatment main effects in the entire outpatient and aftercare
samples, controlling for baseline drinking and site differences, revealed
no significant main effects of treatment on posttreatment percentage of
days abstinent and drinks per drinking day (Project MATCH Research
Group, 1997).
THERAPEUTIC ALLIANCE IN ALCOHOLISM TREATMENT 593
Table 3
Means, Standard Deviations, Skewness, and Kurtosis for Working Alliance Inventory (WAI) Scores
and the Dependent Variables for Outpatient and Aftercare Studies
Variable M(SD)
Outpatient study
Skewness
Aftercare study
Kurtosis M(SD) Skewness Kurtosis
WAI scores and dependent variables
Client WAI total scoreTherapist WAI total scoreTreatment participation (weeks)During treatment
% days abstinent
Drinks per drinking dayPosttreatment
% days abstinentDrinks per drinking day
211.6(24.1)193.2 (24.8)
9.7 (3.3)
83 (25)6.63 (7.15)
75 (28)6.95 (5.96)
-0.88-0.43-1.38
-1.781.94
-1.051.35
0.72-0.14
0.67
2.306.95
-0.082.89
214.8 (23.2)
192.6 (26.5)9.6 (3.5)
92 (19)5.14 (8.86)
83 (25)8.32 (9.59)
-1.05
-0.49-1.32
-2.962.24
-1.67.1.73
1.85-0.05
0.40
8.445.72
1.764.40
Transformed variables3
During treatment% days abstinent
Drinks per drinking dayPosttreatment
% days abstinentDrinks per drinking day
1.12 (0.43)2.07 (1.53)
0.97 (0.46)2.29 (1.31)
-0.93
0.11
-0.37-0.27
-0.04
-0.61
-0.98-0.28
1.35 (0.37)1.35 (1.82)
1.15 (0.45)2.22 (1.84)
-1.931.04
-0.900.22
3.02-0.13
-0.32-0.86
" The drinking variables were transformed before conducting the regression analyses. The percentage of days abstinent variables were subjected to
an arcsin transformation, and the drinks per drinking day variable to a square root transformation.
adjusting for covariates (e.g., demographics, drinking history,
and W\I scores), treatment assignment had relatively little im-
pact on percentage of days abstinent at two sites, whereas at
the remaining three sites, MET clients appeared to have a lower
percentage of days abstinent than TSF and CBT clients.
Aftercare Study
The results of the multiple regression analyses for the after-
care clients are detailed in Table 6. Looking first at the five
blocks of variables preceding entry of the working alliance vari-
ables, we found that the strongest predictions of drinking vari-
ables were again in the context of the client's pretreatment
drinking history. Drinks per drinking day during treatment and
during posttreatment were predicted by pretreatment drinks per
drinking day and AUI scores. Drinks per drinking day posttreat-
ment also was predicted by the number of previous episodes
of alcoholism treatment. Several client and therapist variables
predicted drinks per drinking day outcomes. Client ethnicity,
for example, predicted both drinks per drinking day variables,
with higher rates of drinks per drinking day reported by White
clients. Drinks per drinking day during treatment was also pre-
dicted by client age (negatively) and client gender (higher drinks
per drinking day among men). In terms of therapist characteris-
tics, having a male therapist was associated with higher reports
of drinks per drinking day during treatment and during follow-
up. Therapist age also negatively predicted drinks per drinking
day during posttreatment. Finally, several treatment effects were
found for the posttreatment drinking variables. Overall, MET
clients had lower rates of percentages of days abstinent and
higher rates of drinks per drinking day (Ms — 79% and 8.72,
respectively), whereas TSF clients had higher rates of percent-
ages of days abstinent and lower rates of drinks per drinking
day (Ms = 87% and 7.42, respectively). The means for the
CBT clients were 84% and 8.52, respectively.
In terms of aftercare clients' ratings of the therapeutic alli-
ance, the client WAI scores block was not significant across the
five dependent variables, and no significant two-way interactions
emerged. Therapist ratings of the therapeutic alliance were, how-
ever, significant positive predictors of percentage of days absti-
nent during treatment and posttreatment.
The regression equations evaluating aftercare therapist ratings
produced significant two-way interactions for three of the five
dependent variables. The W\I X Treatment Site interaction was
significant for drinks per drinking day during treatment, percent-
age of days abstinent posttreatment, and drinks per drinking day
posttreatment. Drinks per drinking day posttreatment also was
predicted by the WAI X Treatment Modality interaction, and
percentage of days abstinent posttreatment also was predicted
by the Treatment Modality X Treatment Site interaction. Exami-
nation of the variables used to represent the WAI X Treatment
Site interactions allowed for an assessment of the relationship
between therapist WAI scores and drinking at each aftercare
site. In this regard, the WAI X Treatment Site interaction for
drinks per drinking day during treatment showed a negative
relationship between WAI therapist scores and drinks per drink-
ing day at four sites but a positive relationship at the other two
sites. The interaction for percentage of days abstinent posttreat-
ment showed a modest positive relationship between W\I thera-
594 CONNORS, CARROLL, DiCLEMENTE, LONGABAUGH, AND DONOVAN
Table 4
Correlations Between Client and Therapist Working Alliance Inventory (WAI) Total Scores
and Treatment Participation and Drinking Behavior During Treatment and Posttreatment
Dependent variable
During treatment
WAI total score
Outpatient-client ratingsCBTMETTSFTotal sample
Outpatient-therapist ratingsCBTMETTSFTotal sample
Aftercare-client ratingsCBTMETTSFTotal sample
Aftercare-therapist ratingsCBTMETTSFTotal sample
Treatmentparticipation
.076
.132*
.126
.107**
.024
.077
.196**
.102**
.082-.048-.001
.021
.095
.061
.025
.072
% daysabstinent
.143*
.106
.123
.116**
.193**
.175**
.167*
.162***
-.040.069
-.117-.023
.070
.134
.143
.103*
Drinks perdrinking day
-.105-.114-.075-.092*
-.125-.111-.123-.106**
-.069-.049
.005
.038
.001-.122-.110-.063
Posttreatment
% daysabstinent
.202**
.084
.109
.134**
.148*
.122
.240***
.169***
.111
.127-.112
.040
.212**
.192*
.121
.150**
Drinks perdrinking day
-.180**-.152*-.001-.106**
-.165*-.058-.110-.102**
-.040-.116
.020-.034
.022-.157*
.034-.018
Note. Percentage of days abstinent and drinks per drinking day were transformed using arcsin and square-root transformations, respectively. The sample sizes associated with the above correlations vary slightlybecause of missing data. The ranges for the five dependent variables for the outpatient and aftercare armsby treatment were as follows: For client ratings in the outpatient study, cognitive-behavioral therapy (CBT)= 232-241, motivational enhancement treatment (MET) = 214-233, 12-step facilitation treatment (TSF)= 217-224, total sample = 663-698; for therapist ratings, CBT = 233-244, MET = 207-226, TSF =216-223, total sample = 656-693. For client ratings in the aftercare study, CBT = 178-188, MET =175-185, TSF= 112-117, total sample = 465-490; for therapist ratings, CBT = 179-189, MET = 174-186, TSF = 117-123, total sample = 470-498.*p < .05. **p<m. ***p < .001 (two-tailed).
pist ratings and percentage of days abstinent at four sites, a
markedly stronger positive relationship at a fifth site, and a
modest negative relationship at the sixth site. The relationship
between drinks per drinking day posttreatment and therapist
WAI scores was negative at four sites and positive at two sites.
The Treatment Modality X WAI therapist score interaction for
drinks per drinking day posttreatment showed a strong negative
relationship between therapist WAI scores and drinks per drink-
ing day in the MET condition and a modest positive relationship
in the CBT and TSF conditions. The final interaction, between
treatment site and treatment modality for posttreatment percent-
age of days abstinent, showed generally comparable rates of
posttreatment abstinence across sites, with the exception that
one site's outcomes reflected lower rates of percentage of days
abstinent for CBT and MET and significantly higher rates for
TSF.
Three three-way interactions, two involving client WAI scores
and one involving therapist WAI scores, also emerged. The inter-
action for percentage of days abstinent during treatment ap-
peared to be carried by one site for the TSF condition, where
high client WAI ratings were associated with a lower percentage
of days abstinent during treatment. The interaction for drinks
per drinking day posttreatment was predominantly carried
through the TSF treatment at this same site, where high WAI
ratings by the client were associated with high rates of drinks per
drinking day. In addition, at a second site there was a particularly
strong negative relationship between client WAI scores and
drinks per drinking day for TSF clients. The third interaction,
involving therapist WAI ratings, emerged in the analysis pre-
dicting treatment participation. It appeared that MET therapist
WAI ratings at one site and TSF therapist ratings at two sites
showed a particularly strong positive relationship between WAI
scores and treatment participation, relative to the other treat-
ments at the remaining sites.
Discussion
The main finding regarding the therapeutic alliance in the
present study was its consistent prediction among outpatient
alcoholic clients of treatment participation and positive drinking-
related outcomes, whether the alliance was rated from the client
or therapist perspective. We found this effect even after control-
THERAPEUTIC ALLIANCE IN ALCOHOLISM TREATMENT 595
Table 5
Multiple Regression Analyses Predicting Treatment Participation and Drinking Behavior During the Treatment and
Posttreatment Periods for Outpatient Sample Using Client and Therapist Ratings
Predictor
AR2 during treatmentAR2
treatment % days Drinks perparticipation abstinent drinking day
(n = 698) (n = 689) (n = 689)
A/?2 posttrealment
% days Drinks perabstinent drinking day
(n = 663) (n = 663)
Client WAI
Block 1 : client characteristicsBlock 2: therapist characteristicsBlock 3: client drinking historyBlock 4: treatment siteBlock 5: treatment modalityBlock 6: working alliance
Client WAI total scoreBlock 7: two-way interactions
WAI X Treatment ModalityWAI X Treatment SiteTreatment Modality X Treatment Site
Block 8: three-way interactionWAI X Treatment Modality x Treatment Site
.013
.006
.019*
.011
.011*
.014**(B = .016)
.018
.012
.010
.002
.051***
.008
.014**
.012**(B = .002)
.013
.009
.009
.001
.082***
.005
.007
.008*(B = -.006)
.010
.007
.027**
.002
.100***
.017*
.003
.015***(B = .002)
.011
.015
.015
.010
.114***
.006
.009*
.013**(fl = -.006)
.015
.003
Therapist WAI
Block 1: client characteristicsBlock 2: therapist characteristicsBlock 3: client drinking historyBlock 4: treatment siteBlock 5: treatment modalityBlock 6: working alliance
Therapist WAI total scoreBlock 7: two-way interactions
WAI X Treatment ModalityWAI X Treatment SiteTreatment Modality X Treatment Site
Block 8: three-way interactionWAI X Treatment Modality X Treatment Site
.012
.005
.026**
.010
.008
.013**(B = .016)
.056***
.005
.032***
.014
.009
.010
.001
.053***
.007
.011*
.034***(B = .003)
.034*
.002
.013*
.022*
.013
.014
.001
.080***
.005
.007
.016***(B = -.008)
.017
.007
.031**
.001
.105***
.015*
.002
.032***(B = .004)
.021
.014
.020*
.008
.107***
.006
.007
.015***(fl = -.007)
.022
.008
Note. The change in R2 for each of the two-way interactions represents the increment in variance for that interaction after the remaining twointeractions have been entered. For Block 1, the percentage of variance accounted for by individual interaction terms is presented only if the overallblock was significant. WAI = Working Alliance Inventory.*p<.05. **p<.01. ***p<.001.
ling for a number of covariates, including the client's pretreat-
ment drinking history. Consistent with our hypotheses, the effect
was generally consistent across treatment sites and, to a large
extent, across treatment modalities as well. This finding among
the outpatient sample is consistent with a larger body of litera-
ture indicating the contribution of the therapeutic alliance to
psychotherapy treatment outcome (Horvath, 1994; Horvatn &
Symonds, 1991). The present findings extend this literature to
include alcoholic clients, a population not previously studied in
detail in the context of therapeutic alliance. This endeavor in-
cluded a large sample size, and the fact that its design controlled
for a number of other variables suggests that these findings are
likely to be robust.
Although the data show a consistent indication among outpa-
tients that the therapeutic relationship is an important, indepen-
dent contributor to treatment participation and drinking out-
comes, the proportion of variance in the various outpatient out-
comes explained by the therapeutic alliance was modest (never
exceeding 3.5% across the client and therapist ratings for the
WAI main effects). This may come as a surprise to those who
would have expected the proportion of variance accounted for
to be higher. However, one should note that the present study
included procedures to control for a variety of other sources of
variance, some of which may have effects mediated by therapist
alliance, before evaluating the unique contribution of WAI rat-
ings. Thus, the estimates derived for these data regarding the
therapeutic alliance's contribution to outcome are probably con-
servative. Furthermore, as noted by Bourgeois, Sabourin, and
Wright (1990), the process of behavior change is multidimen-
sional, and it is not likely that any one factor operating as part
of this process will account for a large amount of variance (see
also Orlinsky & Howard, 1986). In fact, the use of multiple
determinants to predict outcomes places an upper limit on the
amount of variance that can be accounted for by any one pre-
dictor (Ahadi & Diener, 1989; Strube, 1991). Nevertheless,
given the methodological strengths of this large multisite clinical
596 CONNORS, CARROLL, DCLEMENTE, LONGABAUGH, AND DONOVAN
Table 6
Multiple Regression Analyses Predicting Treatment Participation and Drinking Behavior During the Treatment and
Posttreattnent Periods for Aftercare Sample Using Client and Therapist Ratings
Predictor
Art2
treatmentparticipation
(n = 490)
Afl2 during treatment AR2 posttreatment
% daysabstinent
(re = 479)
Drinks perdrinking day
(n = 479)
% daysabstinent(n = 465)
Drinks perdrinking day
(n = 465)
Client WAI
Block 1: client characteristics .018 .012Block 2: therapist characteristics .013 .005Block 3: client drinking history .011 .010Block 4: treatment site .029* .018Block 5: treatment modality .001 .004Block 6: working alliance .000 .002
Client WAI total score (B = .001) (B = -.001)Block 7: two-way interactions .037 .021
WAI X Treatment ModalityWAI X Treatment SiteTreatment Modality X Treatment Site
Block 8: three-way interaction ,024 .043*WAI X Treatment Modality X Treatment Site
(B-.
.032**
.019*
.040**
.004
.002
.000-.001)
.034
.036
.022
.015
.056***
.019
.023**
.001
.001)
.038
.024
.041**
.025**
.211**
.008
.012*
.000(B = -.001)
.024
.031»
Therapist WAI
Block 1 : client characteristicsBlock 2: therapist characteristicsBlock 3: client drinking historyBlock 4: treatment siteBlock 5: treatment modalityBlock 6: working alliance
Therapist WAI total scoreBlock 7: two-way interactions
WAI X Treatment ModalityWAI X Treatment SiteTreatment Modality x Treatment Site
Block 8: three-way interactionWAI x Treatment Modality X Treatment Site
.020
.012
.011
.038**
.001
.000(B = .001)
.047
.035*
.009
.005
.007
.016
.002
.013*(B = .002)
.028
.026
.032**
.016*
.046***
.005
.002
.004(8 = -.005)
.054*
.004
.028*
.024
.028
.020
.013
.057***
.022*
.022**
.022***(B = .003)
.066**
.010
.033**
.048**
.012
.039**
.024**
.212***
.009
.010*
.000(B = -.000)
.047*
.013*
.022*
.025
.017
Note. The change in R2 for each of the two-way interactions represents the increment in variance for that interaction after the remaining twointeractions have been entered. For Block 7, the percentage of variance accounted for by individual interaction terms is presented only if the overallblock was significant. WAI = Working Alliance Inventory.*p< .05 . **p<.01. ***p<.001.
trial and the sample size involved, the findings suggest that the
therapeutic alliance, among outpatient alcoholics at least, is a
factor that has an impact on treatment participation and
outcome.
The results in the aftercare study did not mirror the pattern
found in the outpatient study. In fact, client ratings were not
significant predictors of treatment participation or any of the
drinking outcome measures. Therapist ratings were consistent
significant predictors only of the percentage of days abstinent
variable (during both treatment and posttreatment). The reasons
that ratings of the therapeutic alliance among the aftercare cli-
ents did not predict outcomes to the extent found among the
outpatients, especially in terms of client ratings, are not clear.
Relative to the outpatients, the aftercare clients did have a greater
degree of previous alcoholism involvement (e.g., slightly higher
alcohol dependence SC1D counts, greater history of previous
alcoholism treatment), which may have overshadowed the im-
pact of the working alliance or its development. Perhaps more
likely is that the aftercare clients had already completed a course
of intensive alcoholism treatment (either as inpatiems or as part
of a day hospital treatment) in which some degree of abstinence
likely was achieved. This treatment completion may have re-
sulted in the aftercare sample being preselected for compliance
or motivation, among other variables. It may also be that these
clients did not view or value the working alliance as critically as
the outpatients, given their more intensive treatment experience
immediately before the study. However, it should be noted that
the outpatients and aftercare clients had similar rates of treat-
ment participation (Ms = 9.7 and 9.6 weeks, respectively) and
that the client WAI total scores were similarly comparable (Ms
= 211.6 and 214.8, respectively).
Several interactions (mostly within the aftercare sample) indi-
cated that the impact of therapeutic alliance on treatment partici-
pation and outcome was moderated by site or treatment assign-
ment. For example, in the outpatient sample, the interaction
between site and therapist alliance ratings showed a strong linear
THERAPEUTIC ALLIANCE IN ALCOHOLISM TREATMENT 597
relationship between alliance and treatment participation at two
sites, a slight relationship at a third, and no relationship at two
others. In the aftercare arm, the WAI X Treatment Site therapist
score interactions for drinks per drinking day during treatment
and during follow-up showed various magnitudes" of a negative
relationship between the alliance and drinks per drinking day,
except for two sites in each case where this pattern was inexpli-
cably reversed. It is possible that WAI X Treatment Site interac-
tions in the aftercare sample were influenced by the nature of
the relationships that these clients had with treatment personnel
on the inpatient or day hospital units. However, these (as well as
the other two-way interactions) need to be interpreted cautiously
because the values used to evaluate these interactions have been
adjusted for covariation with the blocks of variables entered in
the earlier steps of the equation. Nevertheless, these interactions
do suggest that findings reported at one treatment site may not
necessarily be fully replicated at other treatment sites, even in
the context of the same treatment protocol.
There are limits on the generalizability of these findings that
warrant comment. First, the present data were collected in a
clinical trial including alcoholic clients who agreed to partici-
pate in a clinical research protocol and who received one of
three structured, manual-guided, time-limited interventions. The
extent to which these findings would be replicated in similar
treatments that are less structured or in other treatment modal-
ities is not clear. Second, the samples included individuals who
stayed in treatment at least through the second session and, thus,
do not include those individuals who dropped out of treatment
before the second session. The aftercare sample does not include
individuals who did not complete a more intensive treatment for
alcoholism immediately before the study. Thus, these findings
cannot be immediately generalized to all clients who seek alco-
holism treatment. Finally, it needs to be acknowledged that in-
flation of alpha exists as a concern whenever multiple analyses
are performed. The finding that the WAI scores operated in the
predicted direction across a range of dependent measures argues
against these results being spurious. The findings involving WAI
scores in interaction with other variables were less consistent,
which suggests that they should be viewed more cautiously.
Taken together, these data indicate the important independent
contribution of the therapeutic relationship to treatment partici-
pation and positive treatment outcomes among alcoholic clients
in outpatient treatment. Accordingly, it will be useful to study
and to understand further the factors that contribute to the estab-
lishment and maintenance of a productive therapeutic alliance
and to evaluate the extent to which these findings generalize to
other populations of alcohol abusers.
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Received August 27, 1996
Revision received January 9, 1997
Accepted January 23, 1997 •