Issue 5, Nov 2018 - Clinical Research Centre

35

Transcript of Issue 5, Nov 2018 - Clinical Research Centre

CRC HKL E-NEWSLETTER ISSUE 5

WORDS FROM EDITOR

PAGE 2

Hi readers!

Welcome back to our fifth edition of CRC E-newsletter. How time flies. It’s the end of 2018.

How are you? I hope 2018 has brought you all the success, blessing, good health, happiness and joy.

What have you achieved so far in research field? Have you been involved with any clinical trials or any sorts of

research? If that so, I bet you have familiarised yourself with the term ‘Informed Consent’. In this issue, we would like to

illuminate about the Informed Consent topic, which is one of the very important part before a research is conducted

especially in human being. As you know, informed consent is an essential process whereby it protect subject autonomy

and human rights. Guidelines stated that in obtaining and documenting informed consent, the investigator should comply

with the applicable regulatory requirements and should adhere to Good Clinical Practice (GCP) and to the ethical

principles that have their origin in the Declaration of Helsinki. Let’s have a read in details about the importance of

Inform Consent inside.

In this issue, we also would like to share with all readers about our HKL Research Day 2018 that held on 30th

August 2018. It was a successful event participated by more researchers compared to last year’s event, and attended by

many VIPs and prominent figures in research industry that shared their vast knowledge and experiences. In this

e-newsletter edition, we have included the winners of the research poster competition too. Congratulation to all the

winners!! Let’s take a look on the example of their research posters here. Who knows it can instil some ideas and tips to

the new researchers out there who are about to learn on how to do a research poster.

Apart from that, we would also like to share other trainings which were successfully organized by CRC HKL

throughout 2018 inclusive of the interdepartmental trainings that were mutually agreed between CRC HKL and few other

clinical departments in HKL. Looking forward for more interdepartmental trainings collaboration in the coming years.

As for publication, we have listed our HKL staffs’ Publications for 2018. By looking at the number of

publications that has increased year by year, it shows something that we should be proud of. Congratulations to all

researchers who manage to published their research findings. We believed it was not an easy-peasy process but definitely

worth and satisfying once the paper has successfully published right? I hope the achievements that we shared in this

newsletter edition will motivate more young researchers out there to continue their research work and aim to get the

research findings published.

Before I ended here, just take a moment to follow us in Facebook (www.facebook.com/

ClinicalResearchCentreHKL) and be friend with us (CrcHkl). You can definitely drop your queries/feedbacks in the

comments section. Enjoy your reading and see you on next issue!

Why need of informed consent?

Informed consent is crucial as it

promotes respect for subject’s

autonomy and it also protects the

participants’ right in any research

conducted involving human. The

intent is that participants can

participate in research voluntarily

with full information about what it

means for them to take part, and

that they give consent before they

participate the research.

What is informed consent?

Informed consent is a voluntary

agreement to participate in

research and it’s not merely a

form that is signed but it is a

process, in which the subject has

the understanding of the research

and its risks.

What are the components in a valid informed consent?

An Informed consent emphasizes a process where the clinical research

participant must receive and comprehend information appropriately to make an

autonomous decision. An informed consent process can be termed as complete,

valid, and meaningful if all four criteria of

information disclosure, competence, comprehen-

sion, and voluntariness are effectively satisfied. It

is essential to consider that competence or

capacity of an individual to make decision

depends on his/her ability to understand relevant

information, to appreciate the nature of situation

along with its consequence, to reason the given

information, and the ability to communicate

choice.

INFORMED CONSENT

Evolution of informed consent

Informed consent evolution begins with Nuremberg Code (1947) which developed in response to the Nuremberg

Trial of Nazi Doctors who performed unethical experimentation during World War II. This code emphasized that

voluntary consent is required in clinical research studies and researchers should minimise risk and harm, make

sure the risks not significantly outweigh the potential benefit in any clinical research.

Later in 1964, World Medical Association in Helsinki, Finland adopted 12 principles to guide researchers on ethical

considerations related to biomedical research. It emphasizes the distinction between the medical care that

directly benefits the patients and research that may or may not provide direct benefit.

In 1979, The Belmont Report sets forth tree principles underlying the ethical conduct of research which are

Respect to person, Beneficence and Justice. Later in 1982, the WHO and Council for Internationals Organizations

of Medical Science, CIOMS created the International Ethical Guidelines for research involving human subjects in

1982. The goal of the guidelines is to support and help implement the ethical principles of the Helsinki

Declaration.

Guideline for GCP was developed by International Conference on Harmonisation (1996) to provide a unified

standard for the European Union, Japan and United States of America to protect the right and wellbeing of human

subject involved in clinical trials and to facilitate mutual acceptance of clinical data by the regulatory authorities

in these regions. Up to date, this guideline is frequently update and widely used as a guidance in protecting

subject autonomy and safety in biomedical research.

The informed consent document must be written in language that is easily understood by the participant, it must minimize the possibility of coercion or undue

influence, and the subject must be given sufficient time to consider participation before giving the consent.

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What are the crucial elements that have

to be included in informed consent ?

Malaysian GCP obliged that the Cultural sensitivity aspect (bovine, porcine)

has to be included in the informed consent documents.

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How do we get informed consent from subjects who are not able to give

informed consent?

For participants who are not able to give informed consent (e.g., unconscious, minor

(<18 years old), or those suffering from severe mental illness or disability), it has be

obtained from a legally acceptable representative (LAR). LAR is an individual or a legal

body authorized under applicable law to consent, on behalf of a prospective participant,

to the individuals’ participation in the clinical trial. If the participant or LAR is unable to

read/write, then an impartial witness should be present during the entire informed

consent process and must append his/her signatures to the

consent form.

An impartial witness is a person who is independent of the trial and cannot be unduly

influenced by the people involved with the trial and who attends the informed consent

process if the participant or the participant's LAR cannot read and who reads the ICF and

any other written information supplied to the participant.

In case of a matured minor (as defined by the ICMR guidelines as an individual <18 years

but ≥7 years), informed assent needs to be taken apart from parental/LAR consent.

INFORMED CONSENT

References: 1.PubMed. Gov 2. Malaysian GCP Guidelines 4th Edition

THIRD HKL RESEARCH DAY 2018

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30th August 2018 manifested as one of our special day for 2018 as our annual event, Hospital

Kuala Lumpur Research Day came into a success. As usual, Main Auditorium Hospital Kuala

Lumpur has been the witness for the event with a very nice decoration of “Traditional” theme. The

Hospital Kuala Lumpur Research Day 2018 was officiated by our Deputy Director General of

Health (Medical) YBhg. Dato’ Dr Hj. Azman Abu Bakar and had a very good attendance response.

Total estimation of 250 delegates which came from our hospital staffs, National CRC and other

hospitals CRC colleagues, Medical Research Review Committee (MREC) representatives, Institute

of Medical Research (IMR) representatives as well as volunteers support from few universities such

as University Kebangsaan Malaysia (UKM). We were lucky as apart from Clinical Research Malaysia (CRM) being our regular

sponsor for research day, we also have MAXIS and PHARMANIAGA that joined in collaborating and sponsoring the event for

this year.

Maintain the same theme as previous year “Research Today for the Best Healthcare of Tomorrow”, today HKL has

progressed to be the favourite site for clinical trials by major pharmaceutical companies worldwide as being the largest hospital in

the country with the biggest pool of patients. HKL is one of the national referral centres whereby multiple disciplinary specialties

are situated to offer the best services in the country. Thus, HKL has always been at the centre of research hub among MOH

facilities.

During the event, we had the opportunity to congratulate and acknowledge our Hospital Research Review Committee

member (HRRC HKL) who had given their continuous support and commitment in reviewing clinical research proposals together

with CRC HKL team before we make the recommendation to MREC. We were glad enough to see our old and new faces of

committees who joined us on board.

We were very honoured to have an inspiring plenary session entitled “My Research Journey” delivered by Professor Dr

Teo Soo Hwang who is currently serves as Chief Executive and Head of Breast Cancer Research Programme of Cancer Research

Malaysia. She had recently been awarded the OBE by Her Majesty Queen Elizabeth II for her contribution to medical research.

Her sharing session on the vast experience of her in clinical research work amazed the audience. We believed that she had instil

the passion and courage to our young researchers who attended the event.

The research day event continued with a forum session entitled “Bridging Public Health and Tertiary Care Through

Research” participated by experienced panels who tried to unravel the potential of HKL, and what challenges might be ahead in

our pursuit towards the seamless integration of research in the current clinical practice. For this, we invited YBhg. Dato’ Dr Goh

Pik Pin (Director of National Clinical Research Centre), YBrs. Dr Haji Tahir Bin Aris (Director of National Institute of Public

Health), YBrs. Dr Saiful Bin Md Sani (Consultant Internal Medicine, HKL) and YBrs. Professor Dr Sanjay Rampal A/L Lekhraj

Rampal (HOD of Social & Preventive Medicine, Faculty of Medicine, UMMC) to lead the hot one hour forum session.

Overall, we had a very good number of participations this year as there were 59 posters and 3 oral presentations were

contested. All the presentations were judged fairly by 8 experienced and dedicated judges. They split into 3 for Oral and 5 for

Poster presentation. Professor Dr Ng Chirk Jenn (Faculty of Medicine, University of Malaya), Dr Ho Tze Ming (MREC Scientific

Reviewer) and Dr Zuraidah Che Man (Clinical Epidemiologist, UKM Medical Centre) led the Oral presentation competition.

While Dr Hajjah Nor Fariza Binti Ngah (Head of Ophthalmology & CRC Hospital Shah Alam), Dr Wong Yoke Fui (Head of

CRC National Cancer Institute, Oncologist), Dr Zaleha Abd Manaf (HRRC member, Former Head or Radiology department

HKL), Dr Ngu Lock Hock (Chairperson of HRRC, Consultant Medical Geneticist) and Mdm Rohana Hassan (HRRC member,

Clinical Pharmacist) be the judges for the poster competition. We would like to congratulate to all the winners for their great

research work and presentation.

Our event was closed by our HKL new director, YBrs. Dr Herric Coray. CRC HKL would like to thank everyone who

has tirelessly contributed towards making this event a success. We hope that we continue to show our commitment in ensuring a

flourishing research culture in HKL and pave a distinctive path for our future generation. See you in the HKL Research Day 2019.

HKL RESEARCH DAY 2018 AT A GLANCE

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DELEGATES AND

OFFICIATION

CEREMONY

BOOTH

VISIT

FORUM SESSION

“Bridging Public Health and

Tertiary Care Through

Research”

HOSPITAL RESEARCH

REVIEW COMMITTEE &

CRC HKL MEMBER

POSTER

COMPETITION

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HKL RESEARCH DAY POSTER COMPETITION WINNER Category: Research

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HKL RESEARCH DAY POSTER COMPETITION WINNER Category: Research

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HKL RESEARCH DAY POSTER COMPETITION WINNER Category: Research

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HKL RESEARCH DAY POSTER COMPETITION WINNER Category: Research

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HKL RESEARCH DAY POSTER COMPETITION WINNER Category: Case Report/Case Series

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TRAINING AND WORKSHOP

Microsoft Excel (Basic) Workshop

Date: 20th February 2018

Venue: CTM Computer Lab, Level 7, SCACC

HKL

Speaker: En. Saiful Rizal B Lamit (CTM HKL)

Pharmacist Role in Industry Sponsored Research (Jointly Organized by CRM & CRC HKL)

Date: 10th April 2018

Venue: Seminar room level 5, SCACC HKL

Speaker: Dr Chew Chun Kiat (NCRC) & Dr Gopi (CRM)

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TRAINING AND WORKSHOP

Introduction of Clinical

Research Workshop

Date: 17-19th April 2018

Venue: Seminar room, JKWP

Kuala Lumpur

Speakers: Dr Zuraidah Che Man (Clinical Epidemiologist, UKM),

Dr Norizan Rosli (NCRC)

Good Clinical Practice Workshop

Date: 23-25 April 2018

Venue: Adamson Hotel, Kuala Lumpur

Speakers: Dr Hjh Salina Abdul Aziz (Head of CRC HKL),

Dr Chee Kok Yoon (Consultant Neuropsychiatrist HKL),

Dr Rosnawati Yahya@Atan

(Consultant Nephrologist HKL),

Ms Evon Chew (National Phar-

maceutical Company Bureau)

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TRAINING AND WORKSHOP

Developing Your Research: Brainstorming, Formulating Research Question and Plan

24th April 2018 at Seminar Room Level 5, SCACC HKL

Speakers: Prof Dr Syed Zulkifli Syed Zakaria (Consultant Neonatologist & Clinical

Epidemiologist, UKM) Prof Dr Ng Chirk Jenn (Family Medicine Physician, UMMC)

Proposal Writing

Workshop

Date: 2nd May 2018

Venue: Seminar Room Level 3, SCACC HKL

Speaker: Dr Zuraidah Che Man (Clinical Epidemiologist, UKM)

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TRAINING AND WORKSHOP

NMRR Registration & Literature Search Workshop

Date: 3rd May 2018 & 27th June 2018

Venue: CTM Computer Lab, Level 7, SCACC HKL

Speakers: Dr Siti Fadhilah Agos & Cik Siti Saleha Adnan

Research Methodology Workshop

Date: 17th-19th July 2018

Venue: Dewan Dato’ Borhan, HKL

Speaker: Dr Arvinder (CRC Perak)

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TRAINING AND WORKSHOP

Speaker:

Dr Woon Yuan Liang

(NCRC)

Critical Appraisal

Workshop

Date:

2nd August 2018

Venue:

Seminar

Room,KKKL

Basic

Statistics

Workshop

Date:

4th-6th September

2018

Venue:

Seminar Room Level 5,

SCACC HKL

Speaker:

En Tengku Mohd

Ikhwan

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TRAINING AND WORKSHOP

Good Clinical

Practice

Workshop

Date:

2nd-4th October 2018

Speakers:

Dr Hung Liang Choo

(Consultant Pediatrician,

HKL)

Ms Carrie Koh (Parexal),

Dr Chee Kok Yoon

(Consultant

Neuropsychiatrist HKL),

Dr Rosnawati Yahya@Atan (Consultant

Nephrologist HKL)

Mr Cheong Ooi Jin (NPCB)

Venue:

Kuala Lumpur

International Hotel

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 18

HKL PUBLICATION 2018

-JANUARY-

No Researchers Research Title Journal Department

1 Wee Yong Tan Efficacy and Safety of Intravenous Recombinant Tissue Plasminogen

Activator in Mild Ischaemic Stroke:

A Meta-analysis

Stroke and

Vascular

Neurology 2018

Neurology

2 Leong KF An 8-Year-Old Child with Delayed Diagnosis of Netherton Sydrome Case Reports in

Pediatrics

Pediatric

3 Silvanathan J A Case of Posterior Tibial Nerve Injury After

Arthroscopic Calcaneoplasty

The Journal of

Foot And Ankle

Surgery

Orthopedic

4 Lai Poh Soon,

Mohamad Helmee

Mohamad Noor

Correlate Alcohol and Toxicology Analysis with Urinary Bladder

Distension on Post-mortem Computed Tomography (PMCT):

A Validation Study

Journal of

Forensic Sciences

Forensic

5 Teh PC Falls in Patients with Parkinson’s Disease (PD) and Their Association

with Bone Mineral Density (BMD)

Parkinsonism and

Related Disorders

Neurology

6 Teh PC Bilateral Globus Pallidus Internus Deep Brain Stimulation for Dystonic

Opisthotonus in Atypical Pantothenate Kinase-Associated

Neurodegeneration Syndrome

Parkinsonism and

Related Disorders

Neurology

7 Teh PC Visual Spatial Dysfunction and Retinal Nerve Fiber Layer Thickness in

Patients with Parkinson Disease

Parkinsonism and

Related Disorders

Neurology

8 Kamarul Azahar Razali Seroprevalence of Hepatitis B Among HIV-Infected Children and

Adolescents Receiving Antiretroviral Therapy in the TREAT Asia

Pediatric HIV Observational Database

The Pediatric

Infectious Disease

Journal

Pediatric

9 Koh KL,

Latib MA

A Rare Case of Median Cleft of Lower Lip in Goldenhar Syndrome Journal of Cleft Lip

Palate and

Craniofacial

Anomalies

Plastic &

Reconstructive

Surgery

10 Thahira A Jamal

Mohamed

Invasive Pneumococcal Disease in a Tertiary Paediatric Hospital

in Malaysia

Online Malaysian

Journal of

Pediatrics and

Child Health

Pediatric

11 Kamarul Azahar Razali Adherence to Antiretroviral Therapy, Stigma and Behavioral Risk

Factors in HIV-Infected Adolescents in Asia

Journal of AIDS

Care, Psychological

and Socio-medical

Aspects of AIDS/

HIV

Pediatric

12 Noraini Mohd Dusa Association Between Polymorphisms of Interleukin-17A G197A and

Interleukin-17F A7488G and Risk of Colorectal Cancer

Journal of Cancer

Research and

Therapeutics

Pathology

13 Hisham A,

Mohamed Sukur S,

Basiron N

A case of Facial Burn Due to the Misuse of Garlic Face Mask for Acne Australasian

Journal of

Dermatology

Plastic &

Reconstructive

Surgery

14 Zahari Z A Case of Persistent Urogenital Sinus:

Pitfalls and Challenges in Diagnosis

Sultan Qaboos

University

Medical journal

Pediatric

Surgery

15 Aziz SA Evaluation of Methadone Treatment in Malaysia: Findings from the

Malaysian Methadone Treatment Outcome Study (MyTOS)

Substance Use &

Misuse

Psychiatry

CRC HKL

16 Noraesah Mahmud

Siti Shahrum

Muhamed Said

Evaluation of Heterozygous Hb E and its Interaction with Deletional

Alpha Thalassemia in Kelantan

Journal of

Biomedical And

Clinical Sciences

Pathology

17 Abdul Kadir WD Photoprotection Awareness and Practices Among Patients with

Systemic Lupus Erythematosus and its Association with Disease Activity

and Severity

Lupus Medical

18 Tang MM 25-hydroxyvitamin D Level Among Vitiligo Patients in Malaysia Journal of

Endocrinology,

Diabetes &

Obesity

Dermatology

19 Poh Khay Wei,

Sharifah Intan Syed

Osman

A Rare Presentation of Plexiform Neurofibroma Journal Of

Surgical Academia

Ophthalmology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 19

HKL PUBLICATION 2018

-FEBRUARY-

No Researchers Research Title Journal Department

1 Chee Kok Yoon To use the Brief Psychiatric Rating Scale to Detect Disorganized Speech in Schizophrenia:

Findings from the REAP-AP study

The Kaohsiung Journal of Medical

Sciences

Psychiatry

2 Siregar JA The Factors Associated with Outcomes in Surgically Managed Ruptured Cerebral Aneurysm

The Malaysian Journal of Medical

Sciences

Neurosurgery

3 Ng PY, Mohd Noordin N

Manchester - Fothergill Procedure for Treatment of Recurrence Procidentia in Young Nulliparous Woman:

A Case Report

The Medical Journal of Malaysia

O&G

4 Thavaratnam LK, Ramasamy S,

Rahmat J, Alagaratnam J

Visual Impairment and Amblyopia in Malaysian Pre-school Children: The SEGPAEDS Study

The Medical Journal of Malaysia

Ophthalmology

5 Teik KW, Ch'ng GS

Novel Biallelic SZT2 Mutations in 3 Cases of Early-Onset Epileptic Encephalopathy

Clinical Genetics

Genetics

6 Saiful Safuan Md Sani Dengue Presenting Symptoms at Admission and its Association with Mortality

International Medical Journal

Medical

7 Nur Hafizah Mohad Azmi

Reliability of Standardized Uptake Value Normalized to Lean Body Mass Using the Liver as a Reference Organ, in Contrast-Enhanced

18F-FDG PET/CT Imaging

Radiation Physics and Chemistry

Radiology

8 Khai Luen Koh, Ali Zain

Surgical Outcome After Less "Rigid" Fixation in Open Cranial Vault Remodeling for Craniosynostosis

The Journal of Craniofacial

Surgery

Plastic & Reconstructive

Surgery

9 Wahid FH Analysis of Malay Arch Width and Anthropometric Correlations Annals of Dentistry (ADUM)

ORL

10 Kunasilan Subramaniam

Thoracic Aortic Dissection. Death May Not Always be Due to Rupture with Haemorrhage.

Unusual Complications Which Can be Missed at Autopsy

Journal of Forensic and Legal

Medicine

Forensic

11 Jagjeet Singh Correction of Inverted Nipples with Twisting and Locking Principle Nipple-Areolar Complex

Reconstruction

Plastic & Reconstructive

Surgery

12 Muhammad Izzuddin Hamzan Normala

Basiron

Transcervical Removal of a Rare Giant Proximal Wharton’s Duct Sialolith and Submandibular Gland

Eurasian Journal of

Medicine and Oncology

Plastic & Reconstructive

Surgery

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HKL PUBLICATION 2018

-MARCH-

No Researchers Research Title Journal Department

1 Huey Yin Leong De Novo Hotspot Variants in CYFIP2 Cause Early-Onset Epileptic

Encephalopathy

Annals of

Neurology Genetics

2 Sazali S, Rusdi A,

Siti HT

Association of ACL Laxity Tests with Arthroscopic Findings in Chronic ACL

and PCL Deficient Knees

The American

Journal of Surgery Orthopedics

3

Kamarul Azahar

Mohd Razali,

Shafnah Adnan

Modification of Initial Highly Active Antiretroviral Therapy (HAART)

Regimen in Pediatric HIV Patients

The Open AIDS

Journal Pediatric

4 Nair HKR Fifty-Patient Study Evaluating the Efficacy of Modified Collagen with

Glycerin in Periwound Skin Management

The International

Journal of Lower

Extremity Wounds

Medical

5 Leong KF Staphylococcal-Scalded Skin Syndrome: Evaluation, Diagnosis,

and Management

World Journal of

Pediatrics Pediatric

6

F. R. Kufian,

N. N. Rapie,

W. N. S. W. Aziz,

S. Radziah

Occupational Dose in Nuclear Medicine Department;

Hospital Kuala Lumpur Experience

3rd International

Conference on

Radiation Safety &

Security in

Healthcare

Services

Nuclear

Medicine

7 Ngu LH Detection of Copy Number Variations in Epilepsy Using Exome Data Clinical Genetics Genetics

8 Jelinar Mohamed Noor New Approach to Management of Traumatic Phacocele with Iris Loss JCRS Online Case

Reports Ophthalmology

9 Lee Chun Lin, R Jason A Rare Case of Spinal Extradural Arachnoid Cyst with Cord Compression Asian Journal

Neurosurgery Neurosurgery

10 Raja Elina Raja Aziddin Multi-Center Performance Evaluations of Tacrolimus and Cyclosporine

Electrochemiluminescence Immunoassays in the Asia-Pacific Region

Annals of

Laboratory

Medicine

Pathology

11

Nurliza Abdullah,

Mohamad Helmee

Mohamad Noor

Quantification of Spheno-Occipital Synchondrosis Fusion in a

Contemporary Malaysian population

Forensic Science

International Forensic

12

Mohamed Rithauddin

Ahmad,

Khoo Teik Beng

Quality of Life in Malaysian Children with Epilepsy Epilepsy &

Behavior Journal

Pediatric

Neurology

13 Leong KF A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions Case Reports in

Pediatrics Pediatric

14

G. Ju Tuang,

G. Ju Tuang,

N. M. Y. Mohammad

Sialolipoma of the Parotid Gland:

An Uncommon Lipoma Variant of Salivary Gland

Acta Medica

Bulgarica ORL

15 Premala Subramaniam The Australian Aged Care and its Implications for the Korean Aging Crisis

Annals of Geriatric

Medicine and

Research

Medical

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 21

HKL PUBLICATION 2018

-APRIL-

No Researchers Research Title Journal Department

1

Fu Liong Hiew,

Shanthi Viswanathan,

Santhi Puvanarajah

Vitiligo Patients in Malaysia Journal of Clinical

Neuroscience Neurology

2

Lay SeeKhoo,

Poh Soon Lai,

Mohd Hilmi Saidin,

Mohd Shah Mahmood

Cling Film Plastic Wrap:

An Innovation for Dead Body Packaging,

Preservation and Transportation by First Responders as a Replacement

for Cadaver Body Bag in Large Scale Disasters

Forensic Science International

Forensic

3 Zainal N Prolonged Survival of Metastatic Hepatocellular Carcinoma:

A Case Report

Journal of

Gastrointestinal

Oncology

Oncology and

Radiotherapy

4 Hiew FL,

Puvanarajah S

Outcome in Chronic Inflammatory Demyelinating Polyneuropathy from

a Malaysian Centre Cver Sixteen Years

Journal of Clinical

Neuroscience Neurology

5

Viswanathan S,

Hung SKY,

Hiew FL

Second Regional Plasmapheresis Conference and Workshop for

Southeast Asia (SEA) on the Immunomodulatory Role of Plasma

Exchange in Central and Peripheral Nervous System Disorders,

Kuala Lumpur, Malaysia

Journal of Clinical

Apheresis Neurology

6 Peitee WO,

Keng WT Expanding the Phenome and Variome of Skeletal Dysplasia

Genetics in

Medicine Genetics

7 Leong KF Pruritic Erythematous Papules in a Previously Well Teenager Pediatrics & Child

Health Pediatric

8 Lin LC,

Jason R A Rare Case of Spinal Extradural Arachnoid Cyst with Cord Compression

Asian Journal of

Neurosurgery Neurosurgery

9 Michael A,

Narasimman S

Mesenteric Bones:

Intra-abdominal Heterotopic Ossification

The Medical

Journal of

Malaysia

General

Surgery

10 Johari Adnan Siregar

Teleneurosurgery:

Outcome of Mild Head Injury Patients Managed in Non- Neurosurgical

Centre in the State of Johor

Malaysian Journal

of Medical

Sciences

Neurosurgery

11

Hiew FL, Ong JJ,

Viswanathan S,

Puvanarajah S.

Outcome in Chronic Inflammatory Demyelinating Polyneuropathy from

a Malaysian Centre Over Sixteen Years

Journal of Cinical

Neuroscience Neurology

12 Seed Hon Fei,

Thong, Kai Shin A Case Series of Dextromethorphan Abuse

Malaysian Journal of Psychiatry

Ejournal Psychiatry

13 Lay Ting Pee Attitudes Toward Concordance and Self-Efficacy in Decision Making: A

Cross-Sectional Study on Pharmacist-Patient Consultations

Patient Preference

and Adherence Pharmacy

14

Kenneth Teow Kheng

Leong,

Nor Akmal Bahari,

Jamalia Rahmat,

Safinaz Mohd Khialdin

A Rare Complication of MRSA Lid Abscess and Orbital Abscess Following

Strabismus Surgery in a Child

Journal of Surgical

Academia UKM Ophthalmology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 22

HKL PUBLICATION 2018

-MAY-

No Researchers Research Title Journal Department

1 Keng WT

Clinical, Biochemical, and Molecular Overview of Transaldolase

Deficiency and Evaluation of the Endocrine Function:

Update of 34 patients

Journal of

Inherited

Metabolic Disease

Genetics

2 Lee AMH,

Aziz SA

Metabolic Syndrome in First Episode Schizophrenia, Based on the

National Mental Health Registry of Schizophrenia (NMHR) in a General

Hospital in Malaysia:

A 10-Year Retrospective Cohort Study

International

Journal of

Environmental

Research and

Public Health

Psychiatry

CRC HKL

3 Leong KF Tinea Imbricata The Journal of

Pediatrics Pediatric

4 Harikrishna K.R.Nair Microcurrent as an Adjunct Therapy to Accelerate Chronic Wound

Healing and Reduce Patient Pain

Journal of Wound

Care Medical

5 Murali Sundram A Novel Calculator for Estimating Prostate Volume in Daily Urology

Services Urology Urology

6

Hishamshah Mohd

Ibrahim,

Salbiah Nawi

Demographic, Clinical and Laboratory Features of Leptospirosis and

Dengue Co-Infection in Malaysia

Journal of Medical

Microbiology Pediatric

7 Thevarajah S Asian Consensus on Assessment and Management of Mild to Moderate

Plaque Psoriasis with Topical Therapy

The Journal of

Dermatology Dermatology

8 Harikrishna K.R.Nair Identifying and Treating Foot Ulcers in Patients with Diabetes:

Saving Feet, Legs and Lives

Journal of Wound

Care Medical

9 Yap Y

Neutral pH and Low-Glucose Degradation Product Dialysis Fluids Induce

Major Early Alterations of the Peritoneal Membrane in Children on

Peritoneal Dialysis

Kidney

International

Journal Reports

Pediatric

10 Silim UA Postnatal Depression and Intimate Partner Violence:

A Nationwide Clinic-Based Cross-Sectional Study in Malaysia

British Medical

Journal Open Psychiatry

11 Viswanathan S

Efficacy and Safety of Fingolimod Therapy in Multi-Ethnic Malaysian

Patients with Relapsing Remitting Multiple Sclerosis:

A Longitudinal Observational Study

Journal of Clinical

Neuroscience Neurology

12 Jie Ping Schee,

Shanthi Viswanathan

Pure Spinal Multiple Sclerosis:

A Possible Novel Entity Within the Multiple Sclerosis Disease Spectrum

Multiple Sclerosis

Journal Neurology

13

Md Sani SS,

Han WH, Gan SP,

Rani NS, Tan HL,

Rathakrishnan K,

A-Shariffuddin MA,

Abd-Rahman M

Prediction of Mortality in Severe Dengue Cases

BioMed Central

Infectious

Diseases

Medical

CRC HKL

14 Anandakrishnan P

Khoo TB

Unusual Case of Cerebral Demyelination and Bilateral Optic Neuritis in

an Infant with Suppurative BCG Lymphadenitis

British Medical

Journal Case

Reports

Pediatrics

Neurology

15 Nurul Huda Umar

Extremely Low Prevalence of Erythromycin-Resistant Streptococcus

Pyogenes Isolates and Their Molecular Characteristics by M Protein

Gene and Multilocus Sequence Typing Methods

Jundishapur

Journal of

Microbiology

Pathology

16

Moonyza Akmal

Ahmad Kamil,

Azura Mohd Affandi

Hidradenitis Suppurativa in Kuala Lumpur, Malaysia:

A 7-Year Retrospective

Dermatology

Research And

Practice

Dermatology

17

Singh MKC

Mahmood MS

Abdullah N

Manifestation of Coronary Atherosclerosis in Klang Valley, Malaysia:

An Autopsy Study

Journal of

Atherosclerosis

and Thrombosis

Forensic

18

Kanchan Thadani,

Chee Kok Yoon, Hanis

Aminah binti John

Mohamad, Norzaini

Rose binti Mohd Zain,

Chan Pek Har, Noor

Jannah binti Ariffin

A Multi-Disciplinary Team Approach to Klüver-Bucy Syndrome:

A Case Report

Malaysian Journal

of Psychiatry Psychiatry

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 23

HKL PUBLICATION 2018

-JUN-

No Researchers Research Title Journal Department

1 Bavanandan S,

Ahmad G

Clinical Efficacy and Feasibility of Whey Protein Isolates

Supplementation in Malnourished Peritoneal Dialysis Patients:

A Multicenter, Parallel, Open-label Randomized Controlled Trial

Clinical Nutrition

ESPEN Nephrology

2 Leong KF A Male Infant Born with an Ulcerated Vascular Mass Paediatrics &

Child Health Pediatric

3 Joseph JP The Effectiveness of Culturally Tailored Video Narratives on Medication

Understanding and Use Self-Efficacy Among Stroke Patients:

A Randomized Controlled Trial Study Protocol

Medicine

(Baltimore) Neurology

4 H.J. Ding,

S.G. Ong,

S.S. Md Sani

AB0577 Characteristics of Valvular Heart Disease in a Monocentric

Malaysian Lupus Cohort

Annals of the

Rheumatic

Diseases Medical

5 Ng Wendy Yin Ling Tubo-Ovarian Abscess Caused by Streptococcus Pneumoniae:

A Usual Pathogen at an Unusual Site

Journal of

Gynecologic

Surgery Radiology

6 Maninderpal Kaur Gill The Evolving Role of Ultrasound Guided Percutaneous Laser Ablation in

Elderly Unresectable Breast Cancer Patients:

A Feasibility Pilot Study

BioMed Research

International Radiology

7

Mukhtaar Shaalih

Tsai Ei Chan,

Siti Nuraihan Nordin,

Sing Yee Hiew,

Eni Juraida Abdul

Rahman, Hishamshah

Mohd Ibrahim,

Zulaiha Muda,

Ida Shahnaz Othman,

Bina Sharine Menon,

Yin Sear Lim,

Kok Hoi The

Outcome of Children with Medulloblastoma Treated in a Tertiary

Referral Centre in Malaysia Neuro-Oncology Pediatric

8 Lok Chin Wong The Effect of Pre‐phototest Sun Exposure on Minimal Erythema Dose

(MED) and Minimal Melanogenic Dose (MMD) Among Skin

Phototypes III, IV and V

Photo-

dermatology,

Photo-

immunology,

Photomedicine

Medical

9 Lee Chee Chan Palliative Care Approach for Preemie :

An Ethical Case Learning Education in

Medicine Journal Pediatric

10 Noor Shaheeran Abdul

Hayi

Predictors of Postpartum Weight Retention Among Urban Malaysian

Mothers:

A prospective Cohort Study

Obesity Research

& Clinical Practice O&G

11 Dusa NM Association Between Polymorphisms of Interleukin-17A G197A and

Interleukin-17F A7488G and Risk of Colorectal Cancer

Journal of Cancer

Research and

Therapeutics Pathology

12 Tan TH Features of Post-Radioiodine Whole Body Scan in Non-Invasive

Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP)

The Medical

Journal of

Malaysia

Nuclear

Medicine

13 Min Moon Tang,

Li Lian Tan,

Asmah Johar

The Utilization of Phototherapy in the Department of Dermatology,

Hospital Kuala Lumpur:

A 5-year Audit

The Medical

Journal of

Malaysia Dermatology

14 Ken Chen Loh,

Min Moon Tang,

Suganthi Thevarajah

Leprosy in Pregnancy:

A Case Series in 4 Dermatology Clinics in Malaysia Malaysian Journal

of Dermatology Dermatology

15 Min Moon Tang Dapsone Hypersensitivity Syndrome and Dapsone-Induced Liver Injury

in Four Malaysian Indigenous Individuals with Leprosy Malaysian Journal

of Dermatology Dermatology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 24

HKL PUBLICATION 2018

-JUN-

No Researchers Research Title Journal Department

16

Sharifah Rosniza,

Min Moon Tan,

Kin Fon Leong,

Sabeera Begum,

Asmah Johar

Patch Testing in Children and Adolescents:

7 Years’ Experience in Hospital Kuala Lumpur

Malaysian Journal

of Dermatology

Dermatology

Pediatric

17 Bee Chin Chen Mitochondrial Neurogastrointestinal Encephalomyopathy Disease in

Three Siblings from Pakistan with a Novel Mutation

Journal of

Pediatric Genetics Genetics

18

Mansharan.K,

Mahmood M.S.,

Nurliza.A.,

Zaleha A.M

Prevalence of Coronary Artery Disease in Young Sudden Death Cases

and Correlation with Post - Mortem Computed Tomography

Calcium Score

Journal of Clinical

Health Sciences Forensic

19 Asmah Johar Review of Current Leprosy Programme and Achievement in Malaysia Malaysian Journal

of Dermatology Dermatology

20 Noor Zalmy Azizan Comparison of the Efficacy of Intralesional Triamcinolone Acetonide and

Silicone Gel Sheeting for the Treatment of Keloids

Malaysian Journal

of Dermatology Dermatology

21 Kin Fon Leong,

Sabeera Begum

Food and Aeroallergens Sensitization Pattern Amongst Atopic

Dermatitis Children in Hospital Kuala Lumpur

Malaysian Journal

of Dermatology

Pediatric

Dermatology

22 Asmah Johar Cutaneous Adverse Drug Reactions in Sabah:

A 3-Year Study Between 2014 - 2016

Malaysian Journal

of Dermatology Dermatology

23

Sabeera Begum,

Sheau Szu Heah,

Kin Fon Leong

Rhabdomyosarcoma Arising in a Giant Congenital Melanocytic Nevus Malaysian Journal

of Dermatology

Pediatric

Dermatology

24

Muhammad Izzuddin

Hamzan,

Normala Basiron,

Fauziah Kassim

Verrucous Hemangioma of the Thumb in Children:

A Rare Presentation

Malaysian Journal

of Dermatology

Plastic &

Reconstructive

Surgery,

Pathology

25 Ahmad Zaid Zanial Empirical Fixed Radioiodine Therapy for Hyperthyroidism: A Sensible

Option and Its Outcome at a Local Nuclear Medicine Referral Centre

The International

Journal of

Medicine and

Nuclear

Medicine

26 Thong Kai Shin

Seed Hon Fei

You Need the Operation, Sign the Consent:

A Case Report on Mental Capacity Assessment

Malaysian Journal

of Psychiatry Psychiatry

27 Azura Mohd Affandi The Development of the Clinical Pathway for a Moderate to Severe

Psoriasis in Malaysia.

International

Medical Journal Dermatology

28 Ganesh Kumar

Ganapathy

Accidental Self-Injection of Xylazine During Work:

A Rare Case

Borneo Journal of

Medical Sciences OSH

29 Nurliza A Determination of Age of Skin Wound by Measuring Collagen Type I and

III Using Picrosirius Polarization Method

International

Journal of Medical

Toxicology & Legal

Medicine

Forensic

30 Jamalia Rahmat,

Sunder Ramasamy

Retinoblastoma in an Older Child:

A Case Report

Malaysian Journal

of Medicine and

Health Sciences

Ophthalmology

31 Koh KL,

Zain A

Surgical Outcome After Less "Rigid" Fixation in Open Cranial Vault

Remodeling for Craniosynostosis

The Journal of

Craniofacial

Surgery.

Plastic & Re‐

constructive

Surgery

32 Chee Kok Yoon A Bibliometric Analysis of Scientific Production on Second-Generation

Anti-Psychotic Drugs in Malaysia

Malaysian Journal

of Medical

Sciences

Psychiatry

33 Maninderpal Kaur Gill

Role of Magnetic Resonance Imaging in the Preoperative Staging and

Work-Up of Patients Affected by Invasive Lobular Carcinoma or Invasive

Ductolobular Carcinoma

BioMedical

Research

International

Radiology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 25

HKL PUBLICATION 2018

-JULY-

No Researchers Research Title Journal Department

1 Mohamed Thahira

Jamal

Characteristics, Mortality and Outcomes at Transition for Adolescents

with Perinatal HIV Infection in Asia AIDS Journal Pediatric

2 Nair HKR Malaysian Team Awarded the WHO Dr. Lee Jong-Wook Memorial Prize

for Public Health

The International

Journal of Lower

Extremity Wounds

Medical

3 Razali KA Models of Support for Disclosure of HIV Status to HIV-Infected Children

and Adolescents in Resource-Limited Settings

Journal of the

International AIDS

Society

Medical

4 Chee Kok Yoon Physical Comorbidities in Older Adults Receiving Antidepressants in Asia

Journal of the

Japanese

Psychogeriatric

Society

Psychiatry

5

Mohd Shah Mahmood,

Fauziah Kassim, Hanip

Rafia, Mohd Saffari

Mohd Haspani,

Azmi Alias

Human Tuberculosis Brain Promotes Neuronal Apoptosis but not in

Astrocytes with High Expression of Vascular Endothelial Growth Factor Tuberculosis

Forensic

Pathology

Neurosurgery

6

Stefanie Kar Yan Hung,

Fu Liong Hiew,

Shanthi Viswanathan,

Santhi Puvanarajah

Conventional and Unconventional Therapies in Typical and Atypical

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) with

Different Clinical Course of Progression

Journal of the

Peripheral

Nervous System

Neurology

7

Carol L,

Yusoff SM,

Rose N,

Rafia MH,

Viswanathan S

Spinal Cryptoccoma Mimicking a Spinal Cord Tumor Complicated by

Cryptococcal Meningitis in an Immunocompetent Patient

Neurological

Society of India

Neurology,

Pathology

Radiology

8 Nair HKR Global Collaborations Create Consensus Journal of Wound

Care Medical

9 Gill MK

The Evolving Role of Ultrasound Guided Percutaneous Laser Ablation in

Elderly Unresectable Breast Cancer Patients:

A Feasibility Pilot Study

Radiation Physics

and Chemistry Radiology

10 Murnilina Abdul Malek Impact of Palm Oil Versus Other Oils on Weight Changes:

A Systematic Review

Food & Nutrition

Sciences CRC HKL

11 Murnilina Abdul Malek

What Information and the Extent of Information Research Participants

Need in Informed Consent Forms:

A Multi-Country Survey

BMC Medical

Ethics CRC HKL

12

Chng Kay Ly, Mohd

Yusmiaidil Putera

Mohd Yusoff,

Ahmad Hafizam Hasmi,

Mohd Shah Mahmood

Death of Two Military Pilots in Hawk-108 Fighter Jet Crash:

A Case Report

Journal of Forensic

Science and

Medicine

Forensic

13

Seow Yeing Yee,

Mohamad Zaimi,

Abdul Wahab,

Rosnawati Yahya,

Ravindran Visvanthan,

Ghazali Ahmad

Everolimus Conversion in Kidney Transplant Recipients:

Is it Safe? Transplantation Nephrology

14

Duratul Ain Hussin,

Peter Hendicott,

Andrew Carkeet,

Philip Baker,

Zalifa Zakiah,

Rusnah Husain,

Azlina Mokhtar,

Zairah Zainal Abidin

Clinical Efficiency Of Optometric Service Pathways:

A Pilot Study in Ampang, Malaysia

Asian Journal of

Ophthalmology Ophthalmology

15 Ghazali Ahmad 24th Report of the Malaysian Dialysis and Transplantation Registry Nephrology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 26

HKL PUBLICATION 2018

-AUGUST-

No Researchers Research Title Journal Department

1 Shanti Viswanathan,

Norzaini Rose

Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders in

Malaysia:

A Comparison in Different Ethnic Groups

Multiple Sclerosis

and Related

Disorders

Neurology

Radiology

2 S. Chandran A Girl with a Traumatic Bronchial Injury

Pediatric

Anesthesia and

Critical Care

Journal

Pediatric

3 Irene Cheah Cost is the Most Important Factor Influencing Active Management of

Extremely Preterm Infants in China Acta Paediatrica Pediatric

4 Shanthi Viswanathan,

Lee Mei Wah

A Nationwide Epidemiological Study on the Prevalence of Multiple

Sclerosis and Neuromyelitis Optica Spectrum Disorder with Important

Multi-Ethnic Differences in Malaysia

Multiple Sclerosis

Journal

Neurology

Pharmacy

5 Hung LC Incomplete Kawasaki Disease in a 44-Day-Old Baby

The Medical

Journal of

Malaysia

Pediatric

6 Ngu LH

Mutation Study of Malaysian Patients with Ornithine

Transcarbamylase Deficiency:

Clinical, Molecular, and Bioinformatics Analyses of Two Novel Missense

Mutations of the OTC Gene

BioMed Research

International Genetics

7 Rosna Yunus,

Murali Sundram

Heterogenous Expression of ERG Oncoprotein in Malaysian Men with

Adenocarcinoma of the Prostate

Malaysian Journal

of Pathology

Pathology

Urology

8 Azura Mohd Affandi Relapsed Lymphoma Mimicking Venous Ulcer:

A Case Report

Medical Journal of

Malaysia Dermatology

9 Kantha Rasalingam Association of Angiogenic Cells in the Tumour Microenvironment and

the Circulating Matured Endothelial Cells in Astrocytic Glioma

International

Medical Journal of

Malaysia

Neuromedical

10 Hishamshah Mohd

Ibrahim

Understanding the Genetic Risk of Childhood Leukemia among the

Orang Asli and Malay in Malaysia :

Mining the Whole Genome Sequence DATABASE

Malaysian Journal

of Biochemistry

and Molecular

Biology

Pediatric

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 27

HKL PUBLICATION 2018

-SEPTEMBER-

No Researchers Research Title Journal Department

1

Chai Har Loo,

Wooi Chiang Tan,

Jyh Jong Tang,

Yek Huan Khor,

Manimala T Manikam,

Dyoi-E Low,

Kam Hong Chan,

Kok Hoe Chan,

Yuen Mey Teoh,

Nurul QA Sohot,

Min Moon Tang,

Lee Chin Chan

The Clinical, Biochemical, and Ultrasonographic Characteristics of

Patients with Hidradenitis Suppurativa in Northern Peninsular

Malaysia:

A Multicenter Study

International

Journal of

Dermatology

Dermatology

2

Teh Pei Chiek,

Norzaine Rose

Mohamad Zain,

Joyce Pauline Joseph

A Rare Case of Asymptomatic Cavernous Sinus Thrombosis in

Neuromyelitis Optica Spectrum Disorder

Medical Research

and Clinical Case

Reports

Neurology

Radiology

3 Gaik Siew Ch'ng PLPBP Mutations Cause Variable Phenotypes of Developmental and

Epileptic Encephalopathy Epilepsia Open Genetics

4 Maninderpal Kaur Clinical Cases

Contrast-

Enhanced Digital

Mammography

(CEDM)

Radiology

5 Leong KF Measles: A Disease Often Forgotten But Not Gone Hong Kong

Medical Journal Pediatric

6 Maninderpal Kaur Implementation of Contrast-Enhanced Mammography in Clinical

Practice CEDM Radiology

7 Maninderpal Kaur Artefacts in CEDM CEDM Radiology

8 Nair HKR

Nano-colloidal Silver and Chitosan Bioactive Wound Dressings in

Managing Diabetic Foot Ulcers:

Case Series

Journal of Wound

Care Medical

9 Nair HKR Increasing Productivity with Smartphone Digital Imagery Wound

Measurements and Analysis

Journal of Wound

Care Medical

10 Nair HKR

Venous Leg Ulcers Managed Using Polyurethane Foam With a

Micropore Dressing:

Two Case Reports

Journal of Wound

Care Medical

11 Nair HKR Bond and Heal:

From Asia with Love

Journal of wound

care Medical

12 Ngu LH

Fourteen New Mutations of BCKDHA, BCKDHB and DBT Genes

Associated With Maple Syrup Urine Disease (MSUD) in Malaysian

Population

Molecular

Genetics and

Metabolism

Reports

Genetics

13 Mohamed

Thahira Jamal

Disease and Treatment-Related Morbidity in Adolescents with

Perinatal HIV Infection in Asia

The Pediatric

Infectious Disease

Journal

Pediatric

14

Nor Fadhilah Madon,

Ahmad Hafizam Hasmi,

Khairul Anuar Zainun,

Hapizah Mohd Nawawi

Spontaneous Subdural Hemorrhage Due to Ruptured Arterivenous

Malformation in a Child

Journal of

Forensic Science

and Medicine

Forensic

15

Lee SZ, AS Halim,

Wan Azman WS,

Arman Z MS

Outcome of the Modified MEEK Technique in Management of Major

Pediatric Burns

Annals of Plastic

Surgery

Plastic &

Reconstructive

Surgery

16 Maninderpal Kaur Gill

Corrigendum to “Role of Magnetic Resonance Imaging in the

Preoperative Staging and Work-Up of Patients Affected by Invasive

Lobular Carcinoma or Invasive Ductolobular Carcinoma”

BioMedical

Research

International

Radiology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 28

HKL PUBLICATION 2018

-OCTOBER-

No Researchers Research Title Journal Department

1 Leong KF Erythema Nodosum World Journal of

Pediatric Pediatric

2

Chow Xiao Hong,

Nik Mohd Yunus M,

Iskandar H,

Razmin G

Extranodal Sinonasal Rosai-Dorfman Disease-A Rare Entity

International

Journal of Human

and Health

Sciences

ORL

Pathology

3 Cheah IGS Preterm Infant Outcomes after Randomization to Initial Resuscitation

with FiO2 0.21 or 1.0

The Journal of

Pediatrics Pediatric

4 Azura Mohd Affandi

Skin Cancer:

13-Year Experience at the Department of Dermatology, Hospital Kuala

Lumpur, Malaysia

Journal of Global

Oncology Dermatology

5 Sanah Mohtar Anesthetic Management of Thoracoscopic Resection of Lung

Lesions in Small Children

Pediatric

Anesthesia Anesthesiology

6 Keng Wee Teik GRIN2D Variants in Three Cases of Developmental and Epileptic

Encephalopathy Clinical Genetics Genetics

7

Nurliza Abdullah,

Mohamad Helmee

Mohamad Noor

Novel Group Variable Selection for Salient Skull Region Selection and Sex

Determination

Advances in Brain

Inspired Cognitive

Systems

Forensic

Radiology

8 Razmin Ghazali Endocan Expression in Placenta of Women with Hypertension

The Journal of

Obstetric and

Gynecology

Research

Pathology

9 Muda Z,

Ibrahim H

Genetic Modifiers of Fetal Haemoglobin (HbF) and Phenotypic

Severity in β-Thalassemia Patients

Current Molecular

Medicine Pediatric

10

Kunasilan

Subramaniam,

Fatin Farisha Fadzlee,

Laipoh Soon,

Nor Fadhilah Madon,

Mohd Hilmi Saidin,

Mohd Shah Mahmood

Association of the Drug of Abuse in Road Traffic Collision Death in

Hospital Kuala Lumpur

Medical Journal of

Malaysia Forensic

11 Siew Cheng Chai Skin Microcirculatory Changes in Relation to Arteriovenous Fistula

Maturation

Indian Journal of

Nephrology

Plastic &

Reconstructive

Surgery

12 Abdullah N,

Noor HM

Anthropometric Analysis of Mandible:

An Important Step for Sex Determination

La Clinica

Terapeutica Forensic

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 29

HKL PUBLICATION 2018

-NOVEMBER-

No Researchers Research Title Journal Department

1 Abdullah N,

Noor MHM

Quantification of Secondary Dentin Formation Based on the Analysis of

MDCT Scans and Dental OPGs in a Contemporary Malaysian

Population

Legal medicine

Japanese Society

of Legal Medicine

Forensic

Radiology

2 Lim C Optical Coherence Tomography Angiography of Optic Disc and

Macula Vessel Density in Glaucoma and Healthy Eyes

Journal of

Glaucoma Ophthalmology

3

Karunakar TVN,

Thayanithi S,

Jelinar Noor MN

Cigarette Smoking on Severity of Primary Angle Closure Glaucoma in

Malay Patients

Journal of

Glaucoma Ophthalmology

4 I. M. Nor

Pan-Asian Adapted ESMO Clinical Practice Guidelines for the

Management of Patients with Metastatic Oesophageal Cancer;

a JSMO-ESMO Initiative Endorsed by CSCO, KSMO, MOS, SSO and TOS

Annals of

Oncology

Oncology

Radiotherapy

5 Leong KF Childhood Solitary Cutaneous Mastocytoma:

Clinical Manifestations, Diagnosis, Evaluation, and Management

Current Pediatric

Reviews Pediatric

6 I. M. Nor

Pan-Asian Adapted ESMO Clinical Practice Guidelines for the

Management of Patients with Metastatic Gastric Cancer;

a JSMO-ESMO Initiative Endorsed by CSCO, KSMO, MOS, SSO and TOS

Annals of

Oncology

Oncology

Radiotherapy

7 G S Ch'ng LBA5 Mainstreaming Genetic Counselling for Genetic Testing of BRCA1

and BRCA2 in Ovarian Cancer Patients in Malaysia (MaGiC study)

Annals of

Oncology Genetic

8 M Y Noor Ashani

212O United in Fight against Prostate Cancer Registry (UFO):

Treatment Patterns and Quality of Life From a Large, Multi-center, Lon‐

gitudinal Cohort Study in Asia

Annals of

Oncology Urology

9 Rosminah M. Kassim,

Ashari Yunus

Lung Disease Classification using GLCM and Deep Features from

Different Deep Learning Architectures with Principal

Component Analysis

The International

Journal of

Integrated

Engineering

Radiology, IPR

10 Subramaniam

Thanimalai

Estimating the Utility Value of Hypoglycaemia According to Severity and

Frequency Using the Visual Analogue Scale (VAS) and

Time Trade-off (TTO) Survey

Journal of

Diabetes and

Metabolic

Disorders

Pharmacy

11 Sunita Bavanandan The Cost of Dialysis in Malaysia: Hemodialysis and Continuous

Ambulatory Peritoneal Dialysis

Malaysian Journal

of Public Health

Medicine

Nephrology

12 Jamal Mohamed,

Thahira A

Early and Late Virologic Failure Following Virologic Suppression in HIV-

Infected Asian Children and Adolescents

Journal of

Acquired Immune

Deficiency

Syndromes

Pediatric

13 N. R. Mohd Zain Automatic white matter lesion detection and segmentation on Magnetic

Resonance Imaging: A Review of Past and Current State-of-the-art

International Journal of

Advances in Soft Computing and Its

Applications

Radiology

14 N. R. Mohd Zain White Matter Lesion Intensity Standardization using Adaptive Landmark

based Brain Tissue Analysis on FLAIR MR Image

International Journal of

Advances in Soft Computing and Its

Applications

Radiology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 30

HKL PUBLICATION 2018

-DECEMBER -

No Researchers Research Title Journal Department

1

Kunasilan

Subramaniam,

Shahmila Serangan,

Lai Poh Soon,

Siew Sheue Feng

Sudden cardiac death due to coronary artery embolism secondary to

native aortic valve endocarditis in a young adult

Egyptian Journal

of Forensic

Sciences

Forensic

2 Ngu LH Diagnosis and Management of Patients with

Mucopolysaccharidoses in Malaysia

Journal of

Mucopolysaccha‐

ridosis and Rare

Diseases

Genetics

3 Hamisah Ishak Endogenous Endophthalmitis:

A 9-year retrospective study at a tertiary referral hospital in Malaysia

Journal of

Ophthalmic

Inflammation and

Infection

Ophthalmology

4 Harikrishna K. R. Nair The Use of Compression to Treat Venous Leg Ulcers: The Inadequacy of

Current Compression Systems Especially in Tropical Nations

Compression and

Chronic Wound

Management

Medical

5 Razmin GHAZALI Cyclooxygenase-2 expression in clear cell renal cell carcinoma Malaysian

Journal Pathology Pathology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 31

HKL PUBLICATION 2018

-UNSPECIFIED-

No Researchers Research Title Journal Department

1

Atif Shamsudin,

Heo Chong Chin,

Ahmad Hafizam

Hasmi, Hapizah Mohd

Nawawi

Septicaemic Melioidosis:

A forensic autopsy case report

Journal of

Forensic Science

and Medicine

Forensic

2

Zulkarnain R,

Ummi Nadiah Y,

Mohd Azmi K

Analisa Deskriptif Kedatangan Pesakit Asma Mei hingga Disember 2017

di Jabatan Kecemasan HKL Serta Hubung Kaitnya dengan Indek

Pencemaran Udara (IPU)

Supplement

Journal/

Proceeding

Unit Kesihatan

Awam

3

Mohammad Hafiz J,

Zulkarnain R,

Ummi Nadiah Y,

Mohd Rizal D

Wabak Hand Food and Mouth Disease (HFMD) di Wad KK5, Institut

Pediatrik Hospital Kuala Lumpur

Supplement

Journal/

Proceeding

Unit Kesihatan

Awam

4

Ummi Nadiah Y,

Nur Muhammad

Syafiq R,

Mohd Azmi K

Identifying Hotspot Smoking Area In Hospital Kuala Lumpur Using

Smoking Index

Supplement

Journal/

Proceeding

Unit Kesihatan

Awam

5

Mohamad Ridzuan

MS,

Rosnani AH,

Hamid O, Azam O,

Shafizi AW,Kayrul HM,

Ummi NY,

Moht Hatta M

Job Satisfaction Among Environmental Health Officer in Ministry of

Health Malaysia

Supplement

Journal/

Proceeding

Unit Kesihatan

Awam

6

Anitha R, Fateha K,

Manjulaa Devi S,

Siti Shahida MS,

Ching SL,

Nurul Hizwani A

Vancomycin Initial Dosing in Adult Dialysis Patients in a Tertiary Care

Hospital (VIDAD)

Laporan

Penyelidikan

Teknikal Bahagian

Perkhidmatan

Farmasi KKM

Pharmacy

7

Hannah AH,

Jacqueline WHY,

Rosmaliah Alias,

Chew Chia Zin,

Teh Hwe Lin,

Ammar Kamar,

Chong Ven Yee,

Yau WK,

Lee Fatt Soon

Risks factors of Falls Among Elderly:

Implications of Fall-Risk Increasing Drugs on Patients with

Comorbidities

Laporan

Penyelidikan

Teknikal Bahagian

Perkhidmatan

Farmasi KKM

Pharmacy

8

Tan Shao Sze,

Amir Samsudin,

Rohanah Alias,

Rosilah Mohamad

Phacoemulsification Tunnel Fungal Infection:

A Report of 2 Cases with Different Outcomes

Malaysian Journal

of Ophthalmology Ophthalmology

9

Tan Shao Sze,

Amir Samsudin,

Nurul Ain Masnon,

Lakana Kumar

Thavaratnam

Lights Off, Lights On:

Amaurosis Fugax in Polycythemia, Can Venesection Help?

Malaysian Journal

of Ophthalmology Ophthalmology

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 32

CRC HKL TAKWIM FOR TRAINING 2019

31 Ogos: Merdeka Day

2 Sept: Awal Muharram (1st)

9 Sept: Agong's Birthday

16 Sept: Malaysia Day

28 Oct: Diwali (27th)

9 Nov: Maulidur Rasul

25 Dis: Christmas

1 Jan: New Year's 21 Jan: Thaipusam

1 Feb: Wilayah Persekutuan Day

5-6 Feb: Chinese New Year

1 Mei: Labour Day 20 Mei: Wesak Day (19th)

22 Mei: Nuzul Quran (6 Mei: Ramadhan)

5-6 Jun: Hari Raya Aidilfitri

11-12 Ogos: Hari Raya Aidiladha

Public Holiday (2019):

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 33

FAREWELL

V I S I T O U R F A C E BOO K

P A G E

EDITORIAL TEAM

ADVISOR

DR. HJH SALINA ABDUL AZIZ

EDITOR-IN-CHIEF

DR NOOR HIDAYU WAHAB

EDITORIAL COMMITTEE

DR IZZATY DALAWI

DR MURNILINA ABDUL MALEK

EN. MOHD IKRAM ZAKI JAAFAR

EN. MOHD AL-HAFIZ

DR NURUL ASYIQIN BINTI AZIZ

Working period: 8 September 2014– 30 August 2018

Reason of farewell: Pursuing her further study in Mas-

ter of Public Health (MPH/DrPH) in Universiti Putra Ma-

laysia (UPM) under full scholarship of Hadiah Latihan

Persekutuan (HLP)

We wish you all the best in your future undertakings.

May Allah s.w.t bless you with great things in life and

ease your journey for MPH/DrPH. Congratulations Dr

Asyiqin.

CRC HKL E-NEWSLETTER ISSUE 5 PAGE 34

CLINICAL RESEARCH CENTRE,

HOSPITAL KUALA LUMPUR, LEVEL 7,

SPECIALIST COMPLEX & AMBULATORY CARE CENTRE (SCACC),

JALAN PAHANG, 50586 KUALA LUMPUR.

PHONE NO. : 03-26155555 EXT 1782/1783

FAX : 03- 2604 0818

email:- [email protected],

[email protected]