Appendix 1. PRISMA-ScR checklist - BMJ Open

Appendix 1. PRISMA-ScR checklist

Section PRISMA-ScR Guideline Checklist

Title Identify the report as a scoping review ✓Abstract Structured summary

Provide a structured summary that includes (as applicable) background, objectives, eligibility criteria, sources of evidence, charting methods, results, and conclusions that relate to the review questions and objectives.

✓

Introduction Rationale Describe the rationale for the review in the context of what is already known.

Explain why the review questions/objectives lend themselves to a scoping review approach.

✓

Objectives Provide an explicit statement of the questions and objectives being addressed with reference to their key elements (e.g., population or participants, concepts, and context) or other relevant key elements used to conceptualize the review questions and/or objectives.

✓

Methods Protocol and registration

Indicate whether a review protocol exists; state if and where it can be accessed (e.g., a Web address); and if available, provide registration information, including the registration number.

✓

Eligibility criteria Specify characteristics of the sources of evidence used as eligibility criteria (e.g., years considered, language, and publication status), and provide a rationale.

✓

Information sources Describe all information sources in the search (e.g., databases with dates of coverage and contact with authors to identify additional sources), as well as the date the most recent search was executed.

✓

Search Present the full electronic search strategy for at least 1 database, including any limits used, such that it could be repeated.

✓ (Appendix 2)

Selection of sources of evidence

State the process for selecting sources of evidence (i.e., screening and eligibility) included in the scoping review.

✓ Data charting process Describe the methods of charting data from the included sources of evidence

(e.g., calibrated forms or forms that have been tested by the team before their use, and whether data charting was done independently or in duplicate) and any processes for obtaining and confirming data from investigators.

✓

Data items List and define all variables for which data were sought and any assumptions and simplifications made.

✓ Critical appraisal of individual sources of evidence

If done, provide a rationale for conducting a critical appraisal of included sources of evidence; describe the methods used and how this information was used in any data synthesis (if appropriate).

Not applicable

Synthesis of results Describe the methods of handling and summarizing the data that were charted. ✓Results Selection of sources of evidence

Give numbers of sources of evidence screened, assessed for eligibility, and included in the review, with reasons for exclusions at each stage, ideally using a flow diagram.

✓

Characteristics of sources of evidence

For each source of evidence, present characteristics for which data were charted and provide the citations.

✓ (Appendix 4)

Critical appraisal within sources of evidence

If done, present data on critical appraisal of included sources of evidence (see item 12).

Not applicable

Results of individual sources of evidence

For each included source of evidence, present the relevant data that were charted that relate to the review questions and objectives.

✓ (Appendix 4)

Synthesis of results Summarize and/or present the charting results as they relate to the review questions and objectives.

✓Discussion Summary of evidence Summarize the main results (including an overview of concepts, themes, and

types of evidence available), link to the review questions and objectives, and consider the relevance to key groups.

✓

Limitations Discuss the limitations of the scoping review process. ✓ Conclusions Provide a general interpretation of the results with respect to the review

questions and objectives, as well as potential implications and/or next steps. ✓

Funding Describe sources of funding for the included sources of evidence, as well as sources of funding for the scoping review. Describe the role of the funders of the scoping review.

✓ (Appendix 4a)

BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any relianceSupplemental material placed on this supplemental material which has been supplied by the author(s) BMJ Open

doi: 10.1136/bmjopen-2021-056938:e056938. 11 2021;BMJ Open, et al. Viana JN

Appendix 2. Search strings used for retrieving relevant articles

Database Search String

Medline (OVID) ((precision or personali* or individuali* or stratif* or Tailo*) adj health).ti. or ((precision or personali* or individuali* or stratif* or Tailo*) adj health).ab.

APA PsycInfo (OVID)

((precision or personali* or individuali* or stratif* or Tailo*) adj health).ti. or ((precision or personali* or individuali* or stratif* or Tailo*) adj health).ab.

Scopus ( TITLE ( ( precision OR personali* OR individuali* OR stratif* OR tailo* ) PRE/0 health ) OR ABS ( ( precision OR personali* OR individuali* OR stratif* OR tailo* ) PRE/0 health ) )

Embase (((precision OR personali* OR individuali* OR stratif* OR tailo*) NEXT/1 health):ti) OR (((precision OR personali* OR individuali* OR stratif* OR tailo*) NEXT/1 health):ab)

Web of Science TI=((precision OR personali* OR individuali* OR stratif* OR tailo*) NEAR/0 health) OR AB=((precision OR personali* OR individuali* OR stratif* OR tailo*) NEAR/0 health)

Grey literature (Google Scholar)

allintitle: "precision health" OR "personalised health" OR "personalized health" OR "individualised health" OR "individualized health" OR "stratified health" OR "tailored health"



Appendix 3. Alphabetical list of included studies in the scoping review (n=225)

1. Abbott L, Gordon Schluck G, Graven L, Martorella G. Exploring the intervention effect moderators of a cardiovascular health promotion study among rural African-Americans. Public health nursing (Boston, Mass). 2018;35(2):126-34.

2. Adams RJ, Sadasivam RS, Balakrishnan K, Kinney RL, Houston TK, Marlin BM. PERSPeCT: Collaborative filtering for tailored health communications. RecSys - Proc ACM Conf Recomm Syst. 2014:329-32.

3. Afzal M, Ali SI, Ali R, Hussain M, Ali T, Khan WA, et al. Personalization of wellness recommendations using contextual interpretation. Expert Sys Appl. 2018;96:506-21.

4. Ahmed MU. A personalized health-monitoring system for elderly by combining rules and case-based reasoning. Studies in health technology and informatics. 2015;211(ck1, 9214582):249-54.

5. Ahola R, Pyky R, Jamsa T, Mantysaari M, Koskimaki H, Ikaheimo TM, et al. Gamified physical activation of young men--a Multidisciplinary Population-Based Randomized Controlled Trial (MOPO study). BMC Public Health. 2013;13(100968562):32.

6. Almeida FA, Michaud TL, Wilson KE, Schwab RJ, Goessl C, Porter GC, et al. Preventing diabetes with digital health and coaching for translation and scalability (PREDICTS): A type 1 hybrid effectiveness-implementation trial protocol. Contemp Clin Trials. 2020;88(101242342):105877.

7. An LC, Demers MRS, Kirch MA, Considine-Dunn S, Nair V, Dasgupta K, et al. A randomized trial of an avatar-hosted multiple behavior change intervention for young adult smokers. Journal of the National Cancer Institute Monographs. 2013;2013(47):209-15.

8. Anderson DJ, Seib C, McCarthy AL, Yates P, Porter-Steele J, McGuire A, et al. Facilitating lifestyle changes to manage menopausal symptoms in women with breast cancer: a randomized controlled pilot trial of The Pink Women's Wellness Program. Menopause (New York, NY). 2015;22(9):937-45.

9. Ant Ozok A, Wu H, Garrido M, Pronovost PJ, Gurses AP. Usability and perceived usefulness of Personal Health Records for preventive health care: a case study focusing on patients' and primary care providers' perspectives. Appl Ergon. 2014;45(3):613-28.

10. Archibald C. Cultural tailoring for an Afro-Caribbean community: a naturalistic approach. Journal of cultural diversity. 2011;18(4):114-9.

11. Arens JH, Hauth W, Weissmann J. Novel App- and Web-Supported Diabetes Prevention Program to Promote Weight Reduction, Physical Activity, and a Healthier Lifestyle: Observation of the Clinical Application. Journal of diabetes science and technology. 2018;12(4):831-8.

12. Atack L, Luke R. The impact of validated, online health education resources on patient and community members' satisfaction and health behaviour. Health Educ J. 2012;71(2):211-8.

13. Atzmueller M, Hayat N, Trojahn M, Kroll D. Explicative human activity recognition using adaptive association rule-based classification. IEEE Int Conf Future IoT Technol, Future IoT. 2018;2018-January:1-6.

14. Avery KNL, Richards HS, Portal A, Reed T, Harding R, Carter R, et al. Developing a real-time electronic symptom monitoring system for patients after discharge following cancer-related surgery. BMC Cancer. 2019;19(1):463.



15. Ayres K, Conner M, Prestwich A, Hurling R, Cobain M, Lawton R, et al. Exploring the question-behaviour effect: randomized controlled trial of motivational and question-behaviour interventions. Br J Health Psychol. 2013;18(1):31-44.

16. Badawi H, Eid M, El Saddik A. A real-time biofeedback health advisory system for children care. Proc IEEE Int Conf Multimedia Expo Workshops, ICMEW. 2012:429-34.

17. Bannink R, Joosten-van Zwanenburg E, van de Looij-Jansen P, van As E, Raat H. Evaluation of computer-tailored health education ('E-health4Uth') combined with personal counselling ('E-health4Uth + counselling') on adolescents' behaviours and mental health status: design of a three-armed cluster randomised controlled trial. BMC Public Health. 2012;12(100968562):1083.

18. Bariya M, Shahpar Z, Park H, Sun J, Jung Y, Gao W, et al. Roll-to-Roll Gravure Printed Electrochemical Sensors for Wearable and Medical Devices. ACS Nano. 2018;12(7):6978-87.

19. Barnes R, Votova K, Rahimzadeh V, Osman N, Penn AM, Zawati MnH, et al. Biobanking for Genomic and Personalized Health Research: Participant Perceptions and Preferences. Biopreserv Biobank. 2020;18(3):204-12.

20. Barron JS, Finkelstein J. Feasibility of providing personalized health information to older adults and their caregivers. IEEE EMBS Spec Top Conf Point-Care (POC) Healthc Technol: Synergy Towards Better Global Healthc, PHT. 2013:232-5.

21. Bassett RL, Ginis KAM. Risky business: the effects of an individualized health information intervention on health risk perceptions and leisure time physical activity among people with spinal cord injury. Disabil Health J. 2011;4(3):165-76.

22. Batool R, Khan WA, Hussain M, Maqbool J, Afzal M, Lee S. Towards personalized health profiling in social network. Proc - Int Conf New Trends Inf Sci, Serv Sci Data Min (NISS, ICMIA NASNIT), ISSDM. 2012:760-5.

23. Bazdarevic SH, Cristea AI. How emotions stimulate people affected by cancer to use personalised health websites. Knowl Manage E-Learn. 2015;7(4):658-76.

24. Beckmann S, Lahmer S, Markgraf M, Meindl O, Rauscher J, Regal C, et al. Generic sensor framework enabling personalized healthcare. IEEE Life Sci Conf, LSC. 2018;2018-January:83-6.

25. Berks D, Hoedjes M, Raat H, Franx A, Looman CWN, Van Oostwaard MF, et al. Feasibility and effectiveness of a lifestyle intervention after complicated pregnancies to improve risk factors for future cardiometabolic disease. Pregnancy hypertension. 2019;15(101552483):98-107.

26. Bidargaddi N, Almirall D, Murphy S, Nahum-Shani I, Kovalcik M, Pituch T, et al. To Prompt or Not to Prompt? A Microrandomized Trial of Time-Varying Push Notifications to Increase Proximal Engagement With a Mobile Health App. JMIR mHealth uHealth. 2018;6(11):e10123.

27. Blake H, Hussain B, Hand J, Rowlands D, Juma A, Evans C. Employee perceptions of a workplace HIV testing intervention. Int J Workplace Health Manag. 2018;11(5):333-48.

28. Blake-Lamb T, Boudreau AA, Matathia S, Tiburcio E, Perkins ME, Roche B, et al. Strengthening integration of clinical and public health systems to prevent maternal-child obesity in the First 1,000Days: A Collective Impact approach. Contemp Clin Trials. 2018;65(101242342):46-52.



29. Borbolla D, Del Fiol G, Taliercio V, Otero C, Campos F, Martinez M, et al. Integrating personalized health information from MedlinePlus in a patient portal. Studies in health technology and informatics. 2014;205(ck1, 9214582):348-52.

30. Bosak KA, Papa VB, Brucks MG, Savage CR, Donnelly JE, Martin LE. Novel Biomarkers of Physical Activity Maintenance in Midlife Women: Preliminary Investigation. BioResearch Open Access. 2018;7(1):39-46.

31. Braun L, Stanguts C, Spitzer O, Hose L, Gunawan M, Kure CE, et al. A wellness program for cardiac surgery improves clinical outcomes. Adv Integr Med. 2014;1(1):32-7.

32. Brown RF, Davis R, Wilson Genderson M, Grant S, Cadet D, Lessard M, et al. African-American patients with cancer Talking About Clinical Trials (TACT) with oncologists during consultations: evaluating the efficacy of tailored health messages in a randomised controlled trial-the TACT study protocol. BMJ open. 2016;6(12):e012864.

33. Brown RF, Muller TR, Olsen A. Australian women's cervical cancer screening attendance as a function of screening barriers and facilitators. Social science & medicine (1982). 2019;220(ut9, 8303205):396-402.

34. Cappelletti ER, Kreuter MW, Boyum S, Thompson T. Basic needs, stress and the effects of tailored health communication in vulnerable populations. Health Educ Res. 2014;30(4):591-8.

35. Chang AK, Park Y-H, Fritschi C, Kim MJ. A family involvement and patient-tailored health management program in elderly Korean stroke patients' day care centers. Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses. 2015;40(3):179-87.

36. Chen L, Xu J, Zhang L, Xue Y. Big data analytic based personalized air quality health advisory model. IEEE Int Conf Autom Sci Eng. 2017;2017-August:88-93.

37. Chen YJ, Wang JK, Liu CY, Yang CY, Chiang YT, Chen CW. Healthcare needs and quality of life in youths with congenital heart disease: Health-promoting behaviors as a mediator. Journal of pediatric nursing. 2019((Chen Y.-J.) Department of Nursing, KK Women's and Children's Hospital, Singapore(Wang J.-K.) Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan(Liu C.-Y.) Department of Speech Language Pathology and Audiology, National Taipei U).

38. Chen Z, Geng J, Wang M, Hu L, de Melo Ghisi GL, Yu H. The Chinese version of the Coronary Artery Disease Education Questionnaire-II (CADEQ-II): translation and validation. Patient Prefer Adherence. 2018;12(101475748):1587-96.

39. Chiang PH, Dey S. Offline and Online Learning Techniques for Personalized Blood Pressure Prediction and Health Behavior Recommendations. IEEE Access. 2019;7:130854-64.

40. Chua HF, Ho SS, Jasinska AJ, Polk TA, Welsh RC, Liberzon I, et al. Self-related neural response to tailored smoking-cessation messages predicts quitting. Nat Neurosci. 2011;14(4):426-7.

41. Colkesen EB, Ferket BS, Tijssen JGP, Kraaijenhagen RA, van Kalken CK, Peters RJG. Effects on cardiovascular disease risk of a web-based health risk assessment with tailored health advice: a follow-up study. Vascular health and risk management. 2011;7(101273479):67-74.

42. Cortese J, Lustria MLA. Can tailoring increase elaboration of health messages delivered via an adaptive educational site on adolescent sexual health and decision making? J Am Soc Inf Sci Technol. 2012;63(8):1567-80.



43. Cote J, Cossette S, Ramirez-Garcia P, De Pokomandy A, Worthington C, Gagnon M-P, et al. Evaluation of a Web-based tailored intervention (TAVIE en sante) to support people living with HIV in the adoption of health promoting behaviours: an online randomized controlled trial protocol. BMC Public Health. 2015;15(100968562):1042.

44. Crosby LE, Joffe NE, Irwin MK, Strong H, Peugh J, Shook L, et al. School Performance and Disease Interference in Adolescents with Sickle Cell Disease. Physical disabilities : education and related services. 2015;34(1):14-30.

45. D'Addario M, Cappelletti ER, Sarini M, Greco A, Steca P. The TTCYB Study Protocol: A Tailored Print Message Intervention to Improve Cardiovascular Patients' Lifestyles. Int J Environ Res Public Health. 2020;17(8).

46. De Gagne JC, Oh J, So A, Haidermota M, Lee S-Y. A Mixed Methods Study of Health Care Experience Among Asian Indians in the Southeastern United States. Journal of transcultural nursing : official journal of the Transcultural Nursing Society. 2015;26(4):354-64.

47. de Souto Barreto P, Lapeyre-Mestre M, Vellas B, Rolland Y. Indicators of influenza and pneumococcal vaccination in French nursing home residents in 2011. Vaccine. 2014;32(7):846-51.

48. de Vries H, Logister M, Krekels G, Klaasse F, Servranckx V, van Osch L. Internet based computer tailored feedback on sunscreen use. Journal of medical Internet research. 2012;14(2):e48.

49. Devaux Y, Dankiewicz J, Salgado-Somoza A, Stammet P, Collignon O, Gilje P, et al. Association of Circulating MicroRNA-124-3p Levels With Outcomes After Out-of-Hospital Cardiac Arrest: A Substudy of a Randomized Clinical Trial. JAMA Cardiol. 2016;1(3):305-13.

50. Donovan E, Chiauzzi E, Floyd DL, Bond K, Wood M. The Feasibility of an Online Health Program for Community College Students. Community Coll J Res Pract. 2012;36(9):637-55.

51. Doove LL, Van Deun K, Dusseldorp E, Van Mechelen I. QUINT: A tool to detect qualitative treatment-subgroup interactions in randomized controlled trials. Psychotherapy research : journal of the Society for Psychotherapy Research. 2016;26(5):612-22.

52. Dos Santos CS, Picoito J, Loureiro I, Nunes C. Clustering of health-related behaviours and its relationship with individual and contextual factors in Portuguese adolescents: results from a cross-sectional study. BMC Pediatr. 2020;20(1):247.

53. Doyle J, Walsh L, Sassu A, McDonagh T. Designing a wellness self-management tool for older adults - Results from a field trial of YourWellness. Proc - PERVASIVEHEALTH: Int Conf Pervasive Comput Technol Healthc. 2014:134-41.

54. Drake C, Meade C, Hull SK, Price A, Snyderman R. Integration of Personalized Health Planning and Shared Medical Appointments for Patients with Type 2 Diabetes Mellitus. SouthMedJ. 2018;111(11):674-82.

55. Dreer LE, Owsley C, Campbell L, Gao L, Wood A, Girkin CA. Feasibility, Patient Acceptability, and Preliminary Efficacy of a Culturally Informed, Health Promotion Program to Improve Glaucoma Medication Adherence among African Americans: " G laucoma Management O ptimism for A frican Americans L iving with Glaucoma. Curr Eye Res. 2016;41(1):50-8.



56. Drost M, Tiersma Y, Glubb D, Kathe S, van Hees S, Calleja F, et al. Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome. Genetics in medicine : official journal of the American College of Medical Genetics. 2020;22(5):847-56.

57. Drozdovska S, Andrieieva O, Yarmak O, Blagii O. Personalization of health-promoting fitness programs for young women based on genetic factors. J Phys Educ Sport. 2020;20:331-7.

58. Elbert SP, Dijkstra A, Oenema A. A Mobile Phone App Intervention Targeting Fruit and Vegetable Consumption: The Efficacy of Textual and Auditory Tailored Health Information Tested in a Randomized Controlled Trial. Journal of medical Internet research. 2016;18(6):e147.

59. Engel J, Blanchet L, Engelke UFH, Wevers RA, Buydens LMC. Towards the disease biomarker in an individual patient using statistical health monitoring. PLoS One. 2014;9(4):e92452.

60. Enwald H, Hirvonen N, Korpelainen R, Huotari ML. Young men's perceptions of fear appeal versus neutral health messages: associations with everyday health information literacy, education, and health. Inf Res. 2015;20(1):12.

61. Enwald HPK, Kortelainen T, Leppäluoto J, Keinänen-Kiukaanniemi D, Jämsä T, Oinas-Kukkonen H, et al. Perceptions of fear appeal and preferences for feedback in tailored health communication: An explorative study among pre-diabetic individuals. Inf Res. 2013;18(3).

62. Enwald HPK, Niemela RM, Keinanen-Kiukaanniemi S, Leppaluoto J, Jamsa T, Herzig K-H, et al. Human information behaviour and physiological measurements as a basis to tailor health information. An explorative study in a physical activity intervention among prediabetic individuals in Northern Finland. Heatlth Info Libr J. 2012;29(2):131-40.

63. Fadhil A, Wang Y, Reiterer H. Assistive Conversational Agent for Health Coaching: A Validation Study. Methods Inf Med. 2019;58(1):9-23.

64. Fan K, Aiello AE, Heller KA. Bayesian models for heterogeneous personalized health data. arXiv preprint arXiv:150900110. 2015.

65. Fan X, Zhao Y, Wang H, Tsui KL. Forecasting one-day-forward wellness conditions for community-dwelling elderly with single lead short electrocardiogram signals. BMC Med Inform Decis Mak. 2019;19(1):285.

66. Faro JM, Orvek EA, Blok AC, Nagawa CS, McDonald AJ, Seward G, et al. Dissemination and Effectiveness of the Peer Marketing and Messaging of a Web-Assisted Tobacco Intervention: Protocol for a Hybrid Effectiveness Trial. JMIR RES Protoc. 2019;8(7):e14814.

67. Fayorsey RN, Wang C, Chege D, Reidy W, Syengo M, Owino SO, et al. Effectiveness of a Lay Counselor-Led Combination Intervention for Retention of Mothers and Infants in HIV Care: A Randomized Trial in Kenya. Journal of acquired immune deficiency syndromes (1999). 2019;80(1):56-63.

68. Ferrao JL, Mendes JM, Painho M. Modelling the influence of climate on malaria occurrence in Chimoio Municipality, Mozambique. Parasites Vectors. 2017;10(1):260.

69. Ferrer RA, Lipkus IM, Cerully JL, McBride CM, Shepperd JA, Klein WMP. Developing a scale to assess health regulatory focus. Social science & medicine (1982). 2017;195(ut9, 8303205):50-60.



70. Fucito LM, Hanrahan TH. Heavy-Drinking Smokers' Treatment Needs and Preferences: A Mixed-Methods Study. J Subst Abus Treat. 2015;59(kai, 8500909):38-44.

71. Gamp M, Renner B. Pre-Feedback Risk Expectancies and Reception of Low-Risk Health Feedback: Absolute and Comparative Lack of Reassurance. Applied psychology Health and well-being. 2016;8(3):364-85.

72. Gany F, Levy A, Basu P, Misra S, Silberstein J, Bari S, et al. Culturally tailored health camps and cardiovascular risk among South Asian immigrants. J Health Care Poor Underserved. 2012;23(2):615-25.

73. Gatwood J, Shuvo S, Ross A, Riordan C, Smith P, Gutierrez ML, et al. The Management of Diabetes in Everyday Life (MODEL) program: development of a tailored text message intervention to improve diabetes self-care activities among underserved African-American adults. Translational behavioral medicine. 2020;10(1):204-12.

74. Ghahari RR, Holden RJ, Flanagan ME, Wagner S, Martin E, Ahmed R, et al. Using cardiac implantable electronic device data to facilitate health decision making: A design study. Int J Ind Ergon. 2018;64(Abedtash, H., & Holden, R.J. (2017). Systematic review of the effectiveness of health-related behavioral interventions using portable activity sensing devices (PASDs). http://dx.doi.org/10.1093/jamia/ocx006Ahmad, M., Bloomstein, L., Roelke, M., Bernstein):143-54.

75. Gholizadeh L, Digiacomo M, Salamonson Y, Davidson PM. Stressors influencing Middle Eastern women's perceptions of the risk of cardiovascular disease: a focus group study. Health Care Women Int. 2011;32(8):723-45.

76. Gilmore LA, Klempel MC, Martin CK, Myers CA, Burton JH, Sutton EF, et al. Personalized Mobile Health Intervention for Health and Weight Loss in Postpartum Women Receiving Women, Infants, and Children Benefit: A Randomized Controlled Pilot Study. Journal of women's health (2002). 2017;26(7):719-27.

77. Ginsburg OM, Fischer HD, Shah BR, Lipscombe L, Fu L, Anderson GM, et al. A population-based study of ethnicity and breast cancer stage at diagnosis in Ontario. Current oncology (Toronto, Ont). 2015;22(2):97-104.

78. Gonzales MJ, Riek LD. Co-designing patient-centered health communication tools for cancer care. Proc Int Conf Pervasive Comput Technol Healthc Workshops, PervasiveHealth. 2013:208-15.

79. Goodman JR, Theis R, Shenkman E. Communicating with underserved audiences: Focus group findings from two studies testing messages with low-income Hispanic, African-American and White audiences. Int J Pharm Healthc Mark. 2017;11(2):133-50.

80. Gordon TF, Bass SB, Ruzek SB, Wolak C, Rovito MJ, Ruggieri DG, et al. Developing a typology of African Americans with limited literacy based on preventive health practice orientation: implications for colorectal cancer screening strategies. J Health Commun. 2014;19(11):1259-77.

81. Gray KM, Clarke K, Alzougool B, Hines C, Tidhar G, Frukhtman F. Internet protocol television for personalized home-based health information: design-based research on a diabetes education system. JMIR RES Protoc. 2014;3(1):e13.



82. Guiñazú MF, Cortés V, Ibáñez CF, Velásquez JD. Employing online social networks in precision-medicine approach using information fusion predictive model to improve substance use surveillance: A lesson from Twitter and marijuana consumption. Inf Fusion. 2020;55:150-63.

83. Guo J. Smartphone-Powered Electrochemical Biosensing Dongle for Emerging Medical IoTs Application. IEEE Trans Ind Inf. 2018;14(6):2592-7.

84. Han W, Ye Y. A repository of microbial marker genes related to human health and diseases for host phenotype prediction using microbiome data. Pacific Symposium on Biocomputing Pacific Symposium on Biocomputing. 2019;24(cwq, 9711271):236-47.

85. Handley MA, Harleman E, Gonzalez-Mendez E, Stotland NE, Althavale P, Fisher L, et al. Applying the COM-B model to creation of an IT-enabled health coaching and resource linkage program for low-income Latina moms with recent gestational diabetes: the STAR MAMA program. Implementation science : IS. 2016;11(1):73.

86. Hardie EA. Australian community responses to the use of genetic testing for personalised health promotion. Aust J Psychol. 2011;63(2):119-29.

87. Haslam C, Kazi A, Duncan M, Twumasi R, Clemes S. Walking Works Wonders: A Workplace Health Intervention Evaluated Over 24 Months. Adv Intell Sys Comput. 2019;824:1571-8.

88. Haze KA, Lynaugh J. Building patient relationships: a smartphone application supporting communication between teenagers with asthma and the RN care coordinator. Computers, informatics, nursing : CIN. 2013;31(6):266-3.

89. Hernandez EM, Vuolo M, Frizzell LC, Kelly BC. Moving Upstream: The Effect of Tobacco Clean Air Restrictions on Educational Inequalities in Smoking Among Young Adults. Demography. 2019;56(5):1693-721.

90. Hollands GJ, Marteau TM. The impact of using visual images of the body within a personalized health risk assessment: an experimental study. Br J Health Psychol. 2013;18(2):263-78.

91. Hong YJ, Lee H, Kim J, Lee M, Choi HJ, Hyeon T, et al. Multifunctional Wearable System that Integrates Sweat-Based Sensing and Vital-Sign Monitoring to Estimate Pre-/Post-Exercise Glucose Levels. Adv Funct Mater. 2018;28(47).

92. Hors-Fraile S, Schneider F, Fernandez-Luque L, Luna-Perejon F, Civit A, Spachos D, et al. Tailoring motivational health messages for smoking cessation using an mHealth recommender system integrated with an electronic health record: a study protocol. BMC Public Health. 2018;18(1):698.

93. Huang Y, Hsu CL, Tseng VS. PURL: Periodic user representation learning from temporal event records for personalized health management. Proc - IEEE Int Conf Big Data Smart Comput, BigComp. 2020:358-65.

94. Huang Z, Zhan X, Xiang S, Johnson TS, Helm B, Yu CY, et al. SALMON: Survival Analysis Learning With Multi-Omics Neural Networks on Breast Cancer. Front Genet. 2019;10(101560621):166.

95. Huh JH. Big data analysis for personalized health activities: Machine learning processing for automatic keyword extraction approach. Symmetry. 2018;10(4).



96. Hwang YC. An e-service design on stroke-precaution for elderly. IET Conf Publ. 2010;2010:336-41.

97. Jackson C, Lewis K, Conner M, Lawton R, McEachan RRC. Are incremental changes in physical activity and sedentary behaviours associated with improved employee health?: A 12-month prospective study in five organisations. Int J Workplace Health Manage. 2014;7(1):16-39.

98. Jacobs M, Johnson J, Mynatt ED. MyPath: Investigating breast cancer patients’ use of personalized health information. Proc ACM Hum Comput Interact. 2018;2(CSCW).

99. Jacobs RJ, Caballero J, Ownby RL, Kane MN. Development of a culturally appropriate computer-delivered tailored Internet-based health literacy intervention for Spanish-dominant Hispanics living with HIV. BMC Med Inform Decis Mak. 2014;14(101088682):103.

100. Jacobs RJ, Kane MN. Teaching disease self-management skills to older adults with multimorbid chronic conditions using mobile technology health education interventions. Iceri2016: 9th International Conference of Education, Research and Innovation. 2016:5607-18.

101. Jang K, Baek YM. How to effectively design public health interventions: Implications from the interaction effects between socioeconomic status and health locus of control beliefs on healthy dietary behaviours among US adults. Health & social care in the community. 2018(9306359).

102. Kampusch S, Kaniusas E, Thürk F, Felten D, Hofmann I, Széles JC. Device development guided by user satisfaction survey on auricular vagus nerve stimulation. Curr Dir Biomed Eng. 2016;2(1):593-7.

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Appendix 4a. Bibliometric information and methodological characteristics of reviewed studies on precision health (n=225)

BIBLIOMETRIC INFORMATION METHODOLOGICAL CHARACTERISTICS

First author

and year of

publication.

Funding

sources

Number

of

authors

Country

(study

setting)

Disciplines of

authors

Institution

of authors

Study aim Study design Technology

being

developed

Focal health

condition

Abbott 2018 Not Supplied 4 USA Medical and Health Sciences

Academia What characteristics of the rural African-American participants in a cardiovascular health promotion study served as moderators of the intervention effects?

Randomised controlled trial

Community/in-person program

Cardiovascular disease

Adams 2014 Institutional, Government, Non-governmental

6 USA Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia A case study evaluating nine rating prediction methods for use in the Patient Experience Recommender System for Persuasive Communication Tailoring, a system developed for use in a clinical trial of CTHC-based smoking cessation support interventions.

Cross sectional Algorithm Smoking

Afzal 2018 Government 9 Not Supplied Information, Computing, and Communication Sciences; Commerce, Management, and Tourism Services

Academia By not handling the contextual factors, the users of the Mining Minds are unable to get the final personalized recommendation services. The main objective of the proposed work is to solve the above mentioned problem by adding the capability to the existing system to exploit not only the user's profile information but also their current context, preferences, and the environmental variables.

Cross sectional study, Text and opinion

Algorithm Sedentary lifestyle

Ahmed 2015 International 1 Spain, Slovenia

Engineering and Technology

Academia This paper proposed a personalized self-served health-monitoring system for elderly in home environment by combining general rules with a case-based reasoning (CBR) approach. Classification accuracy of the CBR retrieval has observed and presented in the paper where percentages of correctly classified cases, sensitivity, specificity and overall accuracy have calculated.

Diagnostic test accuracy study

Algorithm Older adults general health based on blood pressure, blood glucose, weight, activity, pulse, etc.

Ahola 2013 Institutional, Government

10 Finland Social Sciences, Humanities, and Arts (general); Engineering and Technology; Medical and Health Sciences

Academia, Health facility, Non-profit organisation, Defense

The overall aim of the study is to provide new evidence-based knowledge for promoting health and wellbeing in young men. The purpose is to set up a multidisciplinary approach for assessing the effectiveness of 1) an interactive, gamified activation method, based on peer networks and participation, on physical activity, aerobic fitness and relationship towards physical activity in young men 2) the gamified activation on physical health, with special emphasis on weight and related factors, and on mental and social health and wellbeing. The hypotheses are that by the end of the intervention the men in the activation group: 1) are physically more active and fit, and 2) their self-determined and measured health is better and there are fewer obese subjects com-pared to the control group

Randomised controlled trial, Protocol

Individual digital health promotion tool

Physical health, with special emphasis on weight and related factors, and on mental and social health and wellbeing.

Almeida 2020 Industry 13 USA Mathematical Sciences; Medical and Health Sciences

Academia, Industry

To describe the methods and design of a type 1 hybrid effectiveness-implementation trial of a digital diabetes prevention program (DPP) using the iPARIHS (Promoting Action on Research Implementation in Health Services) and RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) frameworks.



Prediabetes

An 2013 Government 9 USA Medical and Health Sciences

Academia The primary objective of this study was to determine whether providing individually tailored cessation messages with or with-out online peer support increased self-reported 30-day abstinence from cigarette use among young adult smokers.



Smoking

Anderson 2015 Non-governmental

7 Australia Medical and Health Sciences

Academia, Health facility

The aims of this study were to (1) develop a behavioral intervention for managing menopausal symptoms in women with breast cancer and (2) evaluate the feasibility and efficacy



Menopausal symptoms caused by breast cancer treatment



of the intervention before developing a larger randomized controlled trial of the program.

AntOzok 2014 Institutional 5 USA Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia Using a case study, we specifically aimed at determining patients' and providers' perceptions regarding (1) whether a PHR system can be useful in improving patient ecare provider interactions, preventive health screening, and compliance with healthier lifestyle behaviors; and (2) the key usability factors of such a system.

Qualitative research


Preventive health

Archibald 2011 Government 1 USA Medical and Health Sciences

Academia The purpose of this study was to discover from interviews, ways to tailor health care interventions to fit the cultural identity of a minority group of people in order to reduce health disparity.



Not Applicable

Arens 2018 Industry 3 Germany Medical and Health Sciences

Health facility

Bring weight reduction and lifestyle modification away from a personal lifestyle topic by involving qualified health care professionals with an evidence-based medical perspective. Capitalize on advanced digital technology to allow for close and personalized interaction of HCPs with the patients. Foster sustainable lifestyle changes and T2DM prevention while staying affordable for the health care system. Establish this way a win-win situation for patients and the health care system

Non-randomised experimental study


Metabolic syndrome

Atack 2012 Institutional, government, Non-governmental

2 Canada Medical and Health Sciences

Academia A study was conducted to implement PEPTalk and to examine patient and community group members' satisfaction and the impact of the health education materials on their health behaviour. Community staff and health providers' experiences with the new education tool were also examined.

Cross sectional study, Qualitative research


Not Supplied

Atzmueller 2018

Not Supplied 4 Not Supplied Not Supplied Academia, Industry

We provide a novel explicative machine learning approach, using adaptive association rule-based classification for human activity recognition.

Clinical prediction rule

Algorithm Parkinson's disease

Avery 2019 Institutional, Government

11 UK Medical and Health Sciences


Here, we describe the development of a hospital EHR (electronic health record)-integrated ePRO system to improve the detection of complications and AEs (adverse effects) after discharge following cancer-related surgery, illustrated in the first instance in the example context of cancer-related major abdominal surgery.


Non-diagnostic implanted medical device

Adverse effects post-discharge

Ayres 2013 Industry 7 UK Behavioural and Cognitive Sciences

Academia, Industry

The present research tested the individual and combined effectiveness of a motivation manipulation and a question-behaviour effect (QBE) manipulation in a fully crossed design using an RCT.




Badawi 2012 Not Supplied 3 Not Supplied Information, Computing, and Communication Sciences

Academia General aim: In this paper, we proposed a personalized health advisory system for children based on real-time biofeedback sensors to provide accurate and up-to-date decisions about childrens' food, clothing, and activities using electronics child record, as the health profile for each child, and ontologies for both vitamins and allergies as knowledge base system to support the decision making.

Cross sectional study


Children's diet

Bannink 2012 Government 5 The Netherlands

Medical and Health Sciences


The aim of this study is to evaluate the effect of two interventions on mental health and health behaviour (alcohol and drug use, smoking, safe sex). Additionally, a process evaluation will be conducted to provide insight in the feasibility of the two interventions. This article describes the design of the study.



Mental health problems, health risk behaviours

Bariya 2018 Government 15 USA Information, Computing, and Communication Sciences;

Academia, Government

We use inks and electrode morphologies designed for electrochemical and mechanical stability, achieving devices with uniform redox kinetics printed on 150 flexible substrate rolls. We show that these electrodes can be functionalized into

Technology/tool testing


Not Supplied



Engineering and Technology

consistently high performing sensors for detecting ions, metabolites, heavy metals, and other small molecules in noninvasively accessed biofluids, including sensors for real-time, in situ perspiration monitoring during exercise. This development of robust and versatile R2R gravure printed electrodes represents a key translational step in enabling large-scale, low-cost fabrication of disposable wearable sensors for personalized health monitoring applications.

Barnes 2020 Government 7 Canada Medical and Health Sciences


Here we present the results of a survey that gauged understanding of the biobanking component and data sharing preferences among stroke patients participating in a GAPH (Genomics and Personalized Health) study and disease-specific biobank.


Diagnostic test Stroke

Barron 2013 Non-governmental

2 USA Medical and Health Sciences

Academia The goal of this study was to assess feasibility of providing personal health information to older adults and their caregivers via web-based patient portal.



Chronic obstructive pulmonary disease, congestive heart failure

Bassett 2011 None 2 Canada Medical and Health Sciences

Academia The purposes of this study were to (1) examine changes in perceived risk for disease following an individualized health information intervention and (2) examine changes in perceived risk for disease as a predictor of changes in leisure time physical activity (LTPA).



Heart disease, obesity, diabetes

Batool 2012 Government 6 Not Applicable (Twitter)

Information, Computing, and Communication Sciences; Engineering and Technology

Academia The proposed system monitors changing health conditions, emotions and interests of users to provide real time personalized health information and guidance from highly qualified physicianâ€™s knowledge. User interests and emotions are extracted by investigating userâ€™s social data which is passed to Smart CDSS for decision making. The response is in the form of approved recommendations or alerts, based on stored clinicians' knowledge. Decision from Smart CDSS is personalized information based on users' interest and health condition. This system improves healthcare activities, self-management of care and enhances communication between patients and physicians.


Algorithm Diabetes

Bazdarevic 2015

Not Supplied 2 Bosnia, Herzegovina

Information, Computing, and Communication Sciences

Academia Two main aims guided this research: ï‚· discovering the factors that can be incorporated into user models to improve personalisation, in particular the connection between emotions and personalisation needs. ï‚· understanding the factors, in particular emotion-related, that can predict subsequent intention to use a health website.

Cohort study Individual digital health promotion tool

Cancer

Beckmann 2018

Not Supplied 8 Germany Information, Computing, and Communication Sciences; Engineering and Technology; Economics

Academia, Industry

After introducing our approach for a personalized healthcare sensor fusion we present our Java Data Collecting (JDC) Framework. The architecture, components and functions will be shown.



Stress

Berks 2019 Government 9 Netherlands Medical and Health Sciences

Health facility

The primary aim of this study is to evaluate the feasibility of a lifestyle intervention program after complicated pregnancies associated with an increased risk of future cardiometabolic disease by comparing the proportion of eligible women who completed the intervention to other lifestyle intervention programs.



Pregnancy complications (preeclampsia, fetal growth restriction and/or gestational diabetes mellitus)

Bidargaddi 2018

Not Supplied 8 Not Supplied Social Sciences, Humanities, and Arts (general); Medical and

Academia, Industry

To test whether sending a push notification containing a contextually tailored health message versus not sending push notification (in moments of availability) results in an increased



Help users find their purpose in life and develop the energy and willpower they need to



Health Sciences; Studies in Human Society

likelihood of proximal engagement with the app (ie, the user is self-monitored via the app at some point in the next 24 hours).

live in accordance with their purpose every day.

Blake 2018 Government 6 UK Medical and Health Sciences; Studies in Human Society

Academia, Industry, Government, Non-profit organisation

The aim of this study was to: determine the feasibility of delivering HIV testing within workplace health checks, describe the demographic characteristics of employees who chose to attend, ascertain the views of attending employees towards workplace HIV testing.



HIV

Blake-Lamb 2018

Institutional, Government, Non-governmental



To describe the study protocol for a quasi-experimental evaluation design of The First 1000 Days program that will examine changes, between 2015 and 2019, in gestational weight gain and prevalence of infant overweight from 0 to 24 months of age. The First 1000 Days program will examine the effectiveness of an early life obesity prevention program for mother-infant pairs.

Non-randomised experimental study, Protocol


Obesity in pregnancy, infant obesity

Borbolla 2014 Not Supplied 8 Argentina Information, Computing, and Communication Sciences; Medical and Health Sciences


This paper describes the implementation process of info buttons within a PHR (personal health record) system as well as the use of MedlinePlus information in Spanish through these info button links.



Medical records/self-management of medical processes

Bosak 2018 Institutional, Government, Non-governmental



The aims of this preliminary study were to investigate: (1) brain biomarkers in the resting state of the left dlPFC in midlife women maintaining physical activity, compared to a previously acquired age-matched inactive control group and (2) functional brain biomarkers during goal-directed task learning and implementation phases between the physical activity maintenance group, and a previously acquired age-matched inactive control group.

Case control study

Diagnostic test Physical activity

Braun 2014 Non-governmental



This study reports on an audit of an existing trial and aims to determine whether the ICWP improved postoperative recovery of CABG and valve surgery patients without increasing the incidence of serious bleeding events. We also assessed whether the ICWP increased participation in rehabilitation programs, was feasible to deliver in a public hospital and was well accepted by patients.



Cardiothoracic surgery recovery

Brown 2016 Non-governmental


Academia The goal of this study is to test the efficacy of (1) providing AA (African-American) patients with cancer with tailored CT (clinical trial) messages with two different depths of tailoring and (2) either providing feedback to oncologists about the patients' tailored CT messages or not.



Cancer

Brown 2019 Not Supplied 3 Australia Medical and Health Sciences; Behavioural and Cognitive Sciences

Academia Thus, we examined if the number of screening barriers and facilitators, and individual barriers and facilitators listed by women, were related to their screening status and prior screening.



Cervical cancer screening

Cappelletti 2014

Government 4 USA Medical and Health Sciences; Behavioural and Cognitive Sciences

Academia We examine the extent to which four unmet basic needs (insufficient food and income, inadequate housing and unsafe neighborhoods and personal safety) and perceived life stress predict recall of a tailored intervention and contacting a recommended health referral contained in the intervention one month later.



Cancer

Chang 2015 Government 4 Korea Medical and Health Sciences

Academia This study aimed to examine the effects of a family involvement and functional rehabilitation program in an adult day care center on elderly Korean stroke patients perceived health, activities of daily living, instrumental activities of daily



Stroke



living, and cost of health services, and on family caregivers’ satisfaction.

Chen 2017 Not Supplied 4 China Information, Computing, and Communication Sciences

Industry This paper proposes a big data analytic (BDA) based personalized air quality health advisory model based on high resolution estimation of air quality concentration, pollutant mixture modeling techniques and personalized air quality health risk estimation. *21 Diseases addressed: Certain infections and parasitic disease; neoplasms; blood and immune mechanism related diseases; endocrine, nutritional, and metabolic diseases; mental and behavioural disorders; diseases of the nervous system; diseases of the eye and adnexa; disease of the ear and mastoid process; diseases of the circulatory system; diseases of the respiratory system; diseases of the digestive system, diseases of the skin and subcutaneous tissue; diseases of the musculoskeletal system and connective tissue; diseases of the genitourinary system; pregnancy, childbirth, and puerperium; certain conditions originating in the perinatal period; congenital malformations, deformations, and chromosomal abnormalities; symptoms, signs, and abnormal clinical and laboratory findings; injury, poisoning and certain other consequences of external causes; external causes of morbidity and mortality; factors influencing health status and contact with health services

Technology/ tool testing

Algorithm 21 disease groups (ICD-10): (See Methods column for more detaisl)

Chen 2019 Government 6 Taiwan Medical and Health Sciences


The aims of this study were to examine the relationship between healthcare needs, health-promoting behaviors and quality of life (QoL) of youths with congenital heart disease (CHD), and to determine whether health-promoting behaviors were a mediating variable.



Congenital heart disease

Chen 2018 Not Supplied 7 China Medical and Health Sciences


The objective of this study was to translate and validate a Chinese version of the Coronary Artery Disease Education Questionnaire-II (CADEQ-II).


Questionnaire Coronary heart disease

Chiang 2019 Institutional 2 USA Information, Computing, and Communication Sciences; Engineering and Technology

Academia To the best of our knowledge, this is the first work investigating the relationship between daily BP prediction and health behavior data collected by wearables, especially in both offline (batch) and online learning scenario.

Cohort study Algorithm hypertension

Chua 2011 Government 7 USA Medical and Health Sciences; Behavioural and Cognitive Sciences

Academia In the present study, we examined whether the neural response to tailored smoking-cessation messages overlaps with self-related processing regions, determined via an independent Self task and, more critically, whether the activation in these regions predicts subsequent real-life quitting.



smoking

Colkesen 2011 Institutional, Industry

6 The Netherlands


Academia, Industry, Health facility

In the present study we evaluated CVD risk changes among employees who voluntarily participated in a Web-based HRA (health risk assessment) including tailored feedback that was offered to them by their employer as part of a worksite health management program. The HRA was designed to collect data that are necessary to screen for the risk of a number of preventable diseases, including CVD, and provide tailored feedback in order to educate, motivate, and empower participants in CVD risk reduction. The primary aim was to measure whether CVD risk was improved after participation in the program at a Dutch worksite.






Cortese 2012 Not Supplied 2 USA Information, Computing, and Communication Sciences, Journalism, Librarianship, and Curatorial Studies

Academia This study examines the effects of a tailored health education site on participants' evaluations of and elaboration on health messages.



Adolescent sexual health and decision making

Cote 2015 Government 11 Canada Medical and Health Sciences; Information, Computing, and Communication Sciences, Engineering and Technology


This study aims to evaluate the effectiveness of a Web-based tailored intervention, TAVIE en sante, in supporting PLHIV to adopt health promoting behaviours, such as smoking cessation, being physically active and eating healthy.



Human Immunodeficiency Virus (HIV)

Crosby 2015 Not Supplied 8 USA Medical and Health Sciences


The current study provides preliminary data on adolescent perceptions of school performance and SCD (sickle cell disease) interference (i.e., how much participants saw SCD as getting in the way of their school performance) and examines the relationship between these variables and demographic factors. A secondary goal of the study was to explore the acceptability of potential educational support strategies and their relationship to demographic variables (e.g., gender, hospitalizations).



Sickle cell disease

Da'Addario 2020

Government 5 Italy Medical and Health Sciences; Studies in Human Society; Behavioural and Cognitive Sciences


This article describes the development of theTime to Change Your Behavior (TTCYB) study protocol, a theory-based, tailored print message intervention to improve compliance with the self-care regimen in patients with cardiovascular diseases.



Cardio-vascular disease: acute coronary syndrome (ACS) or essential hypertension

DeGagne 2015 Institutional 5 USA Medical and Health Sciences

Academia The purpose of this study was to explore experiences of health care utilization, perceptions of the health care system, and the needs for health maintenance and promotion programs in the community among Asian Indian immigrants living in NC Triangle area located in the Southeastern United States.



Health care utilization, perceptions of the health care system, and the needs for health maintenance and promotion programs in the community

deSoutoBarreto 2014

Government 4 France Medical and Health Sciences


The objectives of this study were to examine the vaccination coverage among NH (nursing home) residents characterised by selected medical conditions (at-risk groups) and to investigate if facilities’ structure and internal organisation impact residents’ vaccination in French NHs.


Exploratory Influenza, pneumococcal (vaccination against)

deVries 2012 Not Supplied 6 The Netherlands



In the present study, we first assessed program evaluations of a new, Dutch, Internet Computer Tailored program on skin cancer. We next assessed potential differences in program reactions between respondents with a high- and low-educational level, as well as between patients and non-patients, by assessing perceived advantages and disadvantages pertaining to items such as relevance, completeness, and credibility of the Computer Tailored messages.



Skin cancer

Devaux 2016 Institutional, Government Non-governmental, International

16 Czech Republic, Denmark, Italy, Luxembourg,

Not Supplied Academia, Health facility

In the present ad hoc substudy of the multicenter TTM trial, we addressed the prognostic value of circulating miRNAs for neurologic outcome and mortality 6 months after cardiac arrest.

Cohort study Diagnostic test Neurologic outcome and mortality 6 months after cardiac arrest



the Netherlands, Norway, Sweden, Switzerland, UK

Donovan 2012 Government 5 USA Education Academia, Industry

The current study was designed to test the feasibility of an online, tailored health program for community college students.



Stress management, drugs/alcohol/tobacco, wellness (Nutrition; Physical Activity; Mental Health, and Sexual Health)

Doove 2016 Institutional, Government

4 Not Applicable (data from another study)

Mathematical Sciences; Social Sciences, Humanities, and Arts (general)

Academia In the present paper we will present a nontechnical review of the conceptual basis of QUINT and show its significance for psychological applications. To this end we will subject data from an RCT on drug abuse treatments to a reanalysis with QUINT. This will make it possible to arrive at a more pronounced picture of the information on treatment effectiveness embedded in the data.


Algorithm Not Applicable

DosSantos 2020

None 4 Portugal Medical and Health Sciences


In our study, we aimed to identify and characterise patterns of health-related behaviours among Portuguese adolescents and correlate them with individual and contextual factors.



Health Behaviours: physical activity, eating, and substance use

Doyle 2014 Government 4 Ireland Engineering and Technology

Academia The purpose of this trial was to examine long-term adherence to self-reporting in an older population, to gauge opinions on whether the application increased awareness of one's wellbeing, whether it encouraged people to alter their behaviour in some way and whether people found the application, particularly the feedback provided, useful and usable



Wellness self-management for older adults

Drake 2018 Non-governmental


Academia This study explores the feasibility of integrating personalized health planning (PHP) into a diabetes mellitus shared medical appointments (SMAs) series and implementing the series to leverage the complementary advantages of PHP and SMAs.



Type 2 diabetes

Dreer 2016 Institutional, Government, Non-governmental

6 USA Medical and Health Sciences; Behavioural and Cognitive Sciences

Academia Building upon our previous work, we examined the feasibility and preliminary efficacy of the program (Glaucoma Management Optimism for African Americans Living with Glaucoma) on a sample of AAs (African Americans) who were nonadherent with their glaucoma medications.

Cohort study Community/in-person program

Glaucoma

Drost 2020 Non-governmental

16 Australia, USA, Netherlands

Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia, Industry

Here, we have used the available clinically classified MSH6 variants to calibrate the CIMRA assay output and allow its Bayesian integration with previously calibrated and validated computational analysis into a two-component classification procedure. Then, we addressed the shortage of classified variants for validation purposes by generating a large number of in vivo inactivating Msh6 variants in a cell-based genetic screen. We have extensively characterized these variants, using cellular and biochemical analyses, to confirm their suitability as a proxy for pathogenic human variants. This has enabled the validation of the two-component classification procedure. Moreover, our finding that many inactivating variants identified in the genetic screen match human MSH6 VUS listed in variant databases supports their classification as pathogenic.


Diagnostic test Cancer

Drozdovska 2020

Not Supplied 4 Ukraine Medical and Health Sciences

Academia The study was focused on the substantiation of a personalized approach to designing health-promoting exercise programs for young women based on the genetic factors.


Diagnostic test Physical activity



Elbert 2016 Government 3 Netherlands Medical and Health Sciences; Behavioural and Cognitive Sciences

Academia In summary, we aim to test the efficacy of two different fruit and vegetable promotion interventions delivered via a mobile phone app that communicates persuasive health information via an auditory or textual mode. The efficacy of the auditory and textual intervention will be compared with a control condition in which no intervention is present, and the textual and auditory interventions will be compared to each other.



Not Supplied

Engel 2014 Institutional 5 The Netherlands

Biological Sciences; Medical and Health Sciences

Academia To assess the value of statistical health monitoring for disease diagnosis

Cross sectional study, Clinical prediction rule

Algorithm Diseases: inborn errors of metabolism (IEM) that comprise a substantial group of rare genetic diseases

Enwald 2015 Government, International

3 Finland Social Sciences, Humanities, and Arts (general); Medical and Health Sciences

Academia This study aims at increasing knowledge on perceptions of fear appeal message strategy as a factor affecting information use. The objective is to investigate whether young men with different characteristics perceive health-related fear appeal messages differently in different contexts. If differences are found they could be utilised as a basis to tailor health communication.



Preventive health

Enwald 2013 Government, Non-governmental

8 Finland Social Sciences, Humanities, and Arts (general); Information, Computing, and Communication Sciences; Engineering and Technology; Medical and Health Sciences,

Academia The objective of this study is to specify individual differences in perceptions of a fear appeal message strategy and preferences for feedback message tactics particularly in relation to sex, age, physiological health status (identified by objective measurements of physical fitness, body composition and glucose homeostasis) and changes in health status during the trial.



Preventive health

Enwald 2012 Government, Non-governmental

8 Finland Social Sciences, Humanities, and Arts (general); Information, Computing, and Communication Sciences; Medical and Health Sciences


The aim of this study is to explore the potential to tailor health information on the basis of human information behaviour (HIB), that is, individuals' interest in, searching for, and use of information, and their health status identified by the basic physiological measurements in this context, namely body mass index (BMI), physical fitness classification and glucose test values.



Prediabetes, diabetes

Fadhil 2019 Not Supplied 3 Italy Information, Computing, and Communication Sciences

Academia We describe the results from our validation study to assess the acceptability of this form of coaching by the users, and the feasibility of delivering behavior counseling using the conversational agent medium. Specifically, we are interested in assessing user trust and general satisfaction with the virtual agent to guide our next steps in development and help form hypotheses for future research.



Preventive health/health promotion

Fan 2015 Government 3 USA Mathematical Sciences; Biological Sciences; Medical and Health Sciences

Academia The purpose of this study is to leverage modern technology (such as mobile or web apps in Beckman et al. (2014)) to enrich epidemiology data and infer the transmission of disease.


Algorithm Influenza

Fan 2019 Institutional, Government

4 Hong Kong Information, Computing, and Communication Sciences

Academia We propose a novel framework using single lead ECG signals for forecasting one-day-forward wellness conditions of community-dwelling elderly using short ECG signals. Therefore, two popular deep learning-based approaches called


Algorithm Wellness



long short-term memory network (LSTM)and bidirectional long short-term memory network (BiLSTM) are utilized to forecast one-day-forward wellness conditions for elderly in this study. Meanwhile, two traditional machine learning-based methods of SVM and ANN are also employed for model selection.

Faro 2019 Government, Non-governmental



We aim to evaluate the effectiveness of a machine learning-based approach (recommender system) for computer-tailored health communication (CTHC) over a standard CTHC system based on quit rates and risk reduction. In addition, this study will assess the dissemination of providing access to a peer recruitment toolset on recruitment rate and variability of the sample.



Smoking cessation

Fayorsey 2019 Government 10 Kenya Medical and Health Sciences


The Mother Infant Retention for Health (MIR4Health) study was designed to evaluate the effectiveness of a combination intervention (structural, social, and behavioral) administered by trained lay workers to decrease attrition among HIV-positive pregnant women initiating PMTCT services and their infants through 6 months postpartum in Kenya.


Individual digital health promotion tool; Community/in-person program

HIV in pregnancy

Ferrao 2017 Non-governmental

3 Mozambique Information, Computing, and Communication Sciences; Engineering and Technology

Academia Therefore, the objective of this study was to model the effects of several climatic variables (i.e. maximum, minimum, and mean temperature, relative humidity, precipitation, wind speed, visibility and precipitation) on malaria occurrence in Chimoio municipality, using weekly data to define the role of each variable in malaria occurrence.

Case series Algorithm Malaria

Ferrer 2017 Government 6 USA Science (general); Medical and Health Sciences

Academia, Government, Non-profit organisation

We developed and validated a Health Regulatory Focus Scale (HRFS), which assesses tendencies to avoid negative health consequences (prevention focus) or achieve positive health outcomes (promotion focus).


Survey instrument

Preventive health/health promotion

Fucito 2015 Government 2 USA Medical and Health Sciences


The purpose of this mixed methods study was to understand heavy-drinking smokers' smoking and drinking behaviors and their reactions to a proposed integrated smoking and alcohol treatment program to inform intervention development. The aims were threefold: (1) to describe the self-reported smoking, drinking, and psychological characteristics of heavy-drinking smokers, (2) to characterize heavy drinking smokers' perceptions of smoking and the association between smoking and alcohol use, and (3) to describe heavy drinking smokers' smoking and alcohol treatment preferences.



Smoking, alcohol consumption

Gamp 2016 Institutional, Government

2 Germany Behavioural and Cognitive Sciences

Academia Previous research on responses to health risk feedback has commonly focused on the reception of bad news (highrisk feedback). The reception of low-risk feedback has been comparably neglected since it is assumed that good news is reassuring and readily received. However, field studies suggest mixed responses to low-risk health feedback. Accordingly, we examine whether pre-feedback risk expectancies can mitigate the reassuring effects of good news.



Not Supplied

Gany 2012 None 10 USA Medical and Health Sciences


Because of their potential to overcome these barriers, health fairs are a promising model for CVD intervention for U.S. South Asian immigrants. This study assesses their ability to identify CVD risk factors in the at-risk population.



Cardiovascular disease, diabetes, hypertension, hypercholesterolemia

Gatwood 2020 Government 8 USA Medical and Health Sciences

Academia This paper describes an approach to developing theory-based tailored messages designed for mobile phone delivery using both expert and patient input to develop effective messages specific to an underserved, minority population.



Diabetes



Ghahari 2018 Industry 12 USA Information, Computing, and Communication Sciences; Medical and Health Sciences


Hence, the purpose of this research is to accomplish the following objectives: 1) Explore patient experience with CIEDs and CIED remote monitoring; 2) Identify patient preferences for receiving alerts about heart function and other CIED related data; 3) Understand educational support available to patients with CIEDs and other opportunities for providing educational support.



Chronic heart failure

Gholizadeh 2011

Government 4 Australia Medical and Health Sciences

Academia To better understand Australia-dwelling Middle Eastern womens' lack of service utilization in cardiovascular health, we undertook a study to investigate their understandings and meanings of cardiovascular disease (CVD) and its risk factors.


Individual digital health promotion tool, Community/in-person program


Gilmore 2017 Government 7 USA Medical and Health Sciences

Academia Thus, the objective of this study, E-Moms: A personalized mHealth intervention for health and weight loss in postpartum women, is to capitalize on the ease of increased contact and information delivery through SmartPhones to promote weight loss and improve diet quality in overweight and obese postpartum women enrolled in the supplemental nutrition Women, Infants, and Childrens' program.



Obesity/overweight in postpartum

Ginsburg 2015 Government 7 Canada Medical and Health Sciences

Academia, Health facility, Non-profit organisation

We set out to describe and compare breast cancer stage at diagnosis in Chinese and sa (South Asian) women and in the remaining general population in Ontario.


Algorithm Breast cancer

Gonzales 2013 Not Supplied 2 USA Information, Computing, and Communication Sciences; Engineering and Technology

Academia In this paper, we present our findings from interviews and design workshops we have conducted with patients with gynecological cancer and oncologists.



Ovarian cancer

Goodman 2017 Government 3 USA Medical and Health Sciences; Commerce, Management, and Tourism Services

Academia Thus, the present study summarizes findings from two funded [1] studies that incorporated patient-centered and culturally sensitive approaches to health communication. Specifically, it asks how low-income Hispanic, African-American and non-Hispanic White populations read, understand and respond to health messages with an emphasis on visual messaging.



None

Gordon 2014 Government 9 USA Medical and Health Sciences


Colonoscopy is a particularly important preventive procedure for African Americans because of their excess rates of CRC mortality, more proximal distribution of cancers and adenomas that are addressed more effectively by this method, and the younger mean age at which they develop CRC (Agrawal et al., 2005). Research has shown that African Americans are particularly likely to remain unscreened even when access to screening is available (American Cancer Society, 2010), and although a number of studies have addressed CRC screening behaviors in broad African American populations (Hornik & Ramirez, 2006; James, Campbell, & Hudson, 2002; Katz et al., 2004; Palmer, Midgette, & Buadoo, 2008), no study has used overall orientations toward preventive health practices as a basis for segmentation. This study addressed that gap by developing a typology of patients on the basis of their preventive health practices.


Algorithm Colorectal cancer

Gray 2014 Institutional 7 Australia Information, Computing, and Communication Sciences; Medical

Academia, Industry

This paper aims to report empirical findings about the implementation and evaluation of an integrated Internet protocol television 2.0 system.

Qualitative research, Technology/tool testing


Diabetes



and Health Sciences

Guinazu 2020 Government, Non-governmental

4 Chile Engineering and Technology; Medical and Health Sciences

Academia The aim of this research is to generated an information fusion model of marijuana use tendency confident enough to be employed by stakeholders. So, we will: (a) collect and process the data from Twitter; (b) design a set of algorithms to estimate the tendency of marijuana use in relation to age, localization and gender, moreover, used a set of processes and activities to verify if our model were performing as expected; and (c) fusion of the information in a model to fully characterize the marijuana use population comparable to the national marijuana consume survey for policy makers utilization to improve drug use prevention.


Algorithm Marijuana use

Guo 2018 Not Supplied 1 China Engineering and Technology

Academia In this paper, we proposed a smartphone powering medical dongle working as a miniaturized electrochemical analyzer incorporating with the corresponding glucose and UA electrochemical test strip to measure blood glucose and UA (uric acid), which has the great commercial potentials incorporating with the disposable test strip for glucose and UA monitoring to provide long-term healthcare or medical service for chronic disease.



Diabetes, gout

Han 2019 Institutional, Government

2 USA Information, Computing, and Communication Sciences

Academia In this paper, we report the curation of a repository of microbial marker genes and predictors built from these markers for microbiome-based prediction of host phenotype, and a computational pipeline called Mi2P (from Microbiome to Phenotype) for using the repository. As an initial effort, we focus on microbial marker genes related to two diseases, type 2 diabetes and liver cirrhosis, and immunotherapy efficacy for two types of cancer, non-small-cell lung cancer (NSCLC) and renal cell carcinoma (RCC). We characterized the marker genes from metagenomic data using our recently developed subtractive assembly approach. We showed that predictors built from these microbial marker genes can provide fast and reasonably accurate prediction of host phenotype given microbiome data.


Diagnostic test Type 2 diabetes, Cirrhosis, NSCLC (non-small-cell lung cancer), RCC (renal cell carcinoma)

Handley 2016 Government 10 USA Medical and Health Sciences


This paper describes the theoretical framework and development process for STAR MAMA [Support via Telephone Advice and Resources/Sistema Telefonico de Apoyo y Recoursos-MAMA)]. STAR MAMA is a bilingual (English and Spanish) postpartum diabetes prevention ATSM-based health coaching program designed to decrease diabetes risk behaviors among pGDM women in the San Francisco Bay Area. STAR MAMA is focused specifically on implementation of an adapted version of the DPP among primarily younger pGDM Latina women (ages 18-39 years). An ATSM model was selected at the outset because it allows participants to receive content and health coaching support in their primary language on a weekly basis while remaining in their homes, as traveling to appointments and group sessions are known to be an important barrier to receiving preventive services in community settings. We used a theory-informed step-wise approach based on the recently developed COM-B model and Behaviour Change Wheel (BCW) to adapt the DPP to a high-risk population for type 2 diabetes. To our knowledge, the COM-B model and BCW have not been previously applied to



Gestational diabetes and type 2 diabetes



adapting diabetes prevention interventions for high-risk postpartum women.

Hardie 2011 Institutional 1 Australia Medical and Health Sciences

Academia The current study examined Australiansâ€™ likely intentions to have their genes tested by a (hypothetical) medical expert in order to explore the roles of general trust in the medical industry, specific trust in the medical expert, and beliefs about the risks and benefits of medical advances on the formation of intentions. It was thought that Australians would readily accept the potential application of genetic technology to personalised health promotion, as they generally endorse the benefits of scientific advances (SNTSM, 2003â€“2010) and have high levels of trust in medical experts (Hardie & Critchley, 2008).


Algorithm Intentions to undertake a genetic test

Haslam 2019 Government 5 UK Medical and Health Sciences; Commerce, Management, and Tourism Services

Academia This paper provides an evaluation of Walking Works Wonders over the intervention period (12 months) and a further 12 months follow-up. Identify whether significant differences exist between changes in the outcome measures for the conditions (standard, staged and control)



Physical activity

Haze 2013 Not Supplied 2 USA Medical and Health Sciences

Academia The objective of the beta-testing was to study the feasibility and efficacy of using a smartphone to communicate between a patient with asthma and his/her RN care coordinator.



Asthma

Hernandez 2019

Government 4 USA Social Sciences, Humanities, and Arts (general)

Academia We use indicators of parental and individual educational attainment to test whether smoking bans widen the association between education and smoking behavior.



Smoking

Hollands 2013 Not Supplied 2 UK Medical and Health Sciences

Academia To examine the motivational impact of the addition of a visual image to a personalized health risk assessment and the underlying cognitive and emotional mechanisms.



Not Supplied

Hong 2018 Government, Industry

7 South Korea Physical Sciences; Chemical Sciences; Medical and Health Sciences

Academia Herein, we report an integrated wearable health monitoring system that consists of a disposable sweat-analysis strip for glucose measurement and a wearable smart band for monitoring vital signs such as heart rate (HR), blood oxygen saturation level (SpO2), and physical activity (Figure 1a). Disposable strip-type sensor has been chosen over wearable patch-type sensor in that wearable patches require consideration of sweat inlet/outlet, sweat evaporation, and enzyme degradation over time. In addition, it is difficult for users to perspire continuously without the help of sweat-inducing drugs. By using the integrated system with customized software, we conducted multiple short- and long-term studies with human subjects for different sweat generation methods, physical activities, and collection sites, leading to optimized protocols for accurate and user-friendly sweat analysis. Combining the electrochemical and physiological data collected, we obtained the interdata correlation between glucose-level decrease and physical activity and could estimate post-exercise glucose levels, which is important to prevent the hypoglycemic shock during intense exercise.



Preventive health

Hors-Fraile 2018

International 8 Spain Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia, Industry

The goal of this study is develop and evaluate the quality of a health recommender system to fill this existing gap.


Algorithm Smoking cessation

Huang 2020 Government 3 Taiwan Information, Computing, and

Academia In this paper, we propose a user modeling framework, namely Periodic User Representation Learning (PURL), which learns

Cohort study, Clinical prediction rule

Algorithm Exercise



Communication Sciences

interpretable user representations based on human temporal event records.

Huang 2019 Institutional, Government

11 USA Information, Computing, and Communication Science; Medical and Health Sciences

Academia, Industry

In this study, we implement Deep Learning-based networks to determine how gene expression data predicts Cox regression survival in breast cancer.


Algorithm Breast cancer

Huh 2018 Government 1 Korea Information, Computing, and Communication Sciences

Academia I collected big data by applying the machine learning and crawling method to the unstructured citizen health data in Korea and the search data of Naver, which is a Korean portal company, and Google for keyword analysis for personalized health activities. It visualized the big data using text mining and word cloud. This study collected and analyzed the data concerning the interests related to obesity, change of interest on obesity, and treatment articles.


Algorithm Obesity

Hwang 2010 Not supplied 1 Taiwan Information, Computing, and Communication Sciences

Academia In order to help elderly to obtain knowledge for stroke precaution, this study provides a health information system and its interface design that specifically addresses the physiological issues for elderly.

Randomised controlled trial, Technology/tool testing


Stroke

Jackson 2014 Non-governmental

5 UK Medical and Health Sciences; Behavioural and Cognitive Sciences

Academia The purpose of this paper is to compare the physical activity and sedentary behaviours over 12 months of employees within and across five UK organisations. The paper also explores the association of these health behaviours with objective and self-reported health outcomes; and investigates the association between physical activity and sedentary behaviours.


Algorithm Physical activity, sedentary behavior

Jacobs 2018 Government 3 USA Engineering and Technology

Academia We developed MyPath, a mobile health application, to address these common challenges related to accessing and using health information following a cancer diagnosis, connecting patients with personalized and dynamic educational material.



Breast cancer

Jacobs 2014 Not Supplied 4 USA Medical and Health Sciences; Studies in Human Society

Academia The purpose of this research was to adapt a theoretically-based computer application (initially developed for English-speaking HIV-positive persons) that will provide linguistically and culturally appropriate tailored health education to Spanish-dominant Hispanics with HIV.



HIV

Jacobs 2016 Not Supplied 2 USA Not Supplied Academia The goal of this study was to investigate factors associated with medication adherence in our study population to help guide future disease self-management skills to older adults with multimorbid chronic conditions using mobile technology.



medication adherence for people with for at least two major non-communicable chronic conditions (e.g., diabetes, hypertension, hypercholesterolemia, congestive heart failure)

Jang 2018 Not Supplied 2 USA Information, Computing, and Communication Sciences; The Arts

Academia This study investigated whether individuals with different socioeconomic status (SES) should be provided differently tailored health messages to promote healthy dietary behaviour (HDB).



Not Supplied

Kampusch 2016

Government 6 Austria Engineering and Technology; Medical and Health Sciences

Academia In this paper, we present a survey on satisfaction with and demands for a wearable medical device for percutaneous auricular vagus nerve stimulation (pVNS).



Aspects of improvement of current pVNS treatment for people with chronic lower extremity ulcers, chronic pain,



neurological disorders, acute pain, peripheral arterial occlusive disease, and other diseases

Kang 2019 Government 2 Korea Medical and Health Sciences

Academia We hypothesized that some loci modify the effects of obesity on dyslipidemia risk and analyzed extensive gene-environment interactions at genome-wide levels to search for replicated gene-obesity interactive SNPs.


Algorithm Dyslipidemia - risk factor for CVD

Karatekin 2018 None 3 USA Medical and Health Sciences; Commerce, Management, and Tourism Services

Academia The goal was to identify factors that might affect likelihood of seeking health-related interven-tions for young adults with adverse childhood experiences (ACEs).



Mental health

Karkar 2016 Institutional, Government, Industry

7 USA Social Sciences Humanities, and Arts (general); Information, Computing, and Communication Sciences; Medical and Health Sciences; Studies in Human Society; Behavioural and Cognitive Sciences

Academia Motivated by these gaps, we are pursuing an interdisciplinary research program to develop and test a methodological framework for SCDs in health self-experimentation. This paper details components of this framework and presents a case study: a mobile application supporting self-experimentation for people with irritable bowel syndrome (IBS).

Text and opinion


Irritable bowel syndrome

Kasthurirathne 2020

Non-governmental



The objective of this study was to leverage a comprehensive range of clinical, behavioral, social risk, and social determinants of health factors in order to develop decision models capable of identifying patients in need of various wraparound social services.

Cross sectional study, Clinical prediction rule

Algorithm Need to access social services

Katariya 2018 Not Supplied 5 Not Applicable (Online)

Information, Computing, and Communication Sciences; Engineering and Technology

Industry In this paper, we present a system to generate personalized health recommendations from various providers, based on classification of health related calendar events on the user's smartphone.


Algorithm Health promotion

Kemp 2019 Government 3 USA Social Sciences, Humanities, and Arts (general); Medical and Health Sciences


Our goal is to understand how health care is managed and experienced in AL (Assisted Living) by residents and their care network members.

Cohort study, Qualitative research


Not Applicable

Kemp 2018 Non-governmental



The aims of this study were to determine (i) what is the feasibility of a randomised controlled trial (RCT) investigating a targeted physiotherapy intervention for early-onset hip osteoarthritis (OA) post-hip arthroscopy? and (ii) what are the within-group treatment effects of the physiotherapy intervention and a health-education control group?

Randomised controlled trial, Qualitative research


Early-onset hip osteoarthritis

Kemp 2015 Industry, Non-governmental



The primary aim is to establish the feasibility of a phase III randomised controlled trial investigating a targeted physiotherapy intervention for people with early-onset hip osteoarthritis.






Kerrigan 2020 Government, Industry

15 Dominican Republic, Tanzania

Mathematical Sciences; Medical and Health Sciences; Studies in Human Society


The purpose of this analysis was to assess interest in LA ART (Long-acting injectable antiretroviral therapy) among FSW (female sex workers) living with HIV and to identify factors that could facilitate or inhibit its future use as part of routine care, using a mixed methods approach.

Qualitative research, Non-randomised experimental study


HIV

Kessels 2011 Not Supplied 4 Netherlands Medical and Health Sciences


The present study examined whether the predicted increased attention for the tailored as opposed to general nutrition education messages is moderated by presenting high vs. low threat information about the negative consequences of an unhealthy diet.



Dietary intake

Khalilia 2011 Institutional 3 USA Mathematical Sciences; Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia We present a method utilizing Healthcare Cost and Utilization Project (HCUP) dataset for predicting disease risk of individuals based on their medical diagnosis history. The presented methodology may be incorporated in a variety of applications such as risk management, tailored health communication and decision support systems in healthcare.


Algorithm All diseases in general, top 8 are: Hypertension, Coronary Atherosclerosis, Hyperlipidemia, Dysrhythmia, Other Circulatory Diseases, Diabetes mellitus no complication, Anemia

Kim 2017 Not Supplied 3 Korea Information, Computing, and Communication Sciences

Academia The present study intends to validate the role of different types of information tailoring (personalization vs. customization) and framing (promotion vs. prevention) strategies in shaping user attitudes toward and perceptions of health information and increasing the tendency for self-preservation.



Influenza, food poisoning, bird flu, and mites (as test cases for the messaging strategies evaluated)

Kim 2015 Government 12 Korea Medical and Health Sciences


To solve this problem, we recently generated a new u-healthcare system using a voice inception technique for monitoring information about glucose control, physical activity and diet. We believe that this new method is easier to use. We investigated the efficacy of the new u-healthcare service in managing glucose control without causing hypoglycemia in an elderly population.



Type 2 diabetes

Kitagawa 2015 Institutional 1 Nairobi Policy and Political Science

Academia This paper presents findings from a randomized field experiment that evaluates the impact of a Short Message Service (SMS) sexual health counseling service on individuals' knowledge and behavior in an urban informal settlement of Nairobi, Kenya.



Sexual and reproductive health

Kizakevich 2018

Government 10 USA Science (general); Medical and Health Sciences

Academia In this work, we set out to advance the use of resilience building techniques for individuals with subclinical psychological health issues through innovation in mobile health assessment and self-help intervention. To better support research in this domain, we first created the Personal Health Intervention Toolkit (PHIT), a mobile application (app) framework for personalized health intervention studies. Using this new framework, we implemented PHIT for Duty, an evidence-based app with mindfulness-based relaxation training, behavioral education in sleep quality and alcohol use, and psychometric and psychophysiological data capture for mobile health research. This article introduces and evaluates these technologies in the context of usability and health assessment quality.



PTSD, mental health

Kulyk 2015 Government 4 The Netherlands



The aim of this exploratory user study is to identify the persuasive features and design factors that contribute to the use and uptake of existing and new health technologies.



Sexual health



Lan 2012 Industry 9 Taiwan Information, Computing, and Communication Sciences

Academia, Industry

In this paper, we proposed an effective mechanism for chronic disease risk prediction by mining the data containing historical health records and personal life style information.


Algorithm Not Supplied

Lee 2012 Government 6 Korea Information, Computing, and Communication Sciences; Engineering and Technology; Medical and Health Sciences; Studies in Human Society

Academia The purpose of this study was to explore possibilities related to health promotion nursing interventions utilizing the system as a tool.


Hypertension, obesity

Lee 2014 Government 7 USA Information, Computing, and Communication Sciences; Engineering and Technology; Medical and Health Sciences

Academia The objective of the study was to explore the attitudes and preferences of older adults on warfarin therapy regarding the use of mHealth technology and health games to gain skills for self-management.



Blood clots

Lee 2014 Government 8 Korea Information, Computing, and Communication Science; Engineering and Technology; Medical and Health Sciences


The purposes of this study were to identify the factors that affect the health-related quality of life (HRQoL) of the elderly with chronic diseases and to subsequently develop from such factors a prediction model to help identify HRQoL risk groups that require intervention.


Algorithm Chronic diseases

Leinonen 2017 Institutional, Government, Non-governmental, International

13 Finland Physical Sciences; Information, Computing, and Communication Sciences; Engineering and Technology; Medical and Health Sciences; Studies in Human Society

Academia, Industry, Health facility, Defense

The study aimed to study the feasibility of an automated, gamified, tailored Web-based mobile service aimed at physical and social activation among young men.



Physical activity

Liang 2011 Not Supplied 2 USA Information, Computing, and Communication Sciences

Academia Using netnography, a well structured internet-based ethonography, we analyze discussion threads posted to an obesity support group on a popular health SNS based in the US. We classify e-group members as support seekers and providers.



Various health conditions

Lim 2011 Institutional, Government

12 South Korea Information, Computing, and Communication Sciences; Medical and Health Sciences


To improve quality and efficiency of care for elderly patients with type 2 diabetes, we introduced elderly-friendly strategies to the clinical decision support system (CDSS)-based ubiquitous healthcare (u-healthcare) service, which is an individualized health management system using advanced medical information technology.



Type 2 Diabetes

Lim 2018 Institutional, Government, Non-governmental

17 Singapore Medical and Health Sciences


In this study, our goal was to investigate the utility of consumer-grade wearables in cardiovascular and lipidomics research.



Cardiovascular and metabolic disorders



Liu 2019 Government 4 China Medical and Health Sciences

Academia To explore the effect of individualized health management on angina patients, a total of 98 patients with angina pectoris admitted to our hospital from January 2017 to June 2017 were enrolled.



Angina pectoris

Liu 2020 Government 4 Not Supplied Information, Computing, and Communication Sciences; Behavioural and Cognitive Sciences

Academia We conducted computational experiments on both synthesized data and a clinical autism data set to assess performance quantitatively for coverage of pre-defined cohorts and qualitatively for novel knowledge discovery, respectively. We also conducted a scaling analysis using a distributed computing environment to suggest computational resource needs for when the subpopulation number increases. This work will provide a robust data-driven framework to automatically tailor potential interventions for precision health.


Algorithm Autism

Liu 2018 Institutional, Government


Academia Therefore, the aim of the study was to determine whether a health partner program may alleviate depressive symptoms among healthy overweight/obese individuals at 1 year.



Obesity; depression

Lohmann 2013 Not Supplied 15 Not Supplied Medical and Health Sciences

Industry The aim of the pre-clinical and early clinical data generation was to select the most appropriate biomarkers for prospective hypothesis testing and ultimately for potential companion diagnostics (Dx) development.



Lu 2020 Government 11 Not Supplied Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia Here, we utilized a network-based clustering algorithm (i.e., BigCLAM) to obtain 208 typical SCs across disease conditions on a large-scale symptom network derived from integrated high-quality disease-symptom associations. Furthermore, we evaluated the underlying shared molecular mechanisms for SCs, i.e., shared genes, protein-protein interaction (PPI) and gene functional annotations using integrated networks and similarity measures


Diagnostic test Not Supplied

Lumpkins 2020 Non-governmental


Academia, Non-profit organisation

This study was designed to gather pilot data through community participation with FBOs (faith-based organizations) in the Midwest of the United States, specifically through engagement with African American community members. Participants’ attitudes, perceptions, and beliefs toward genetics and CGT as well as their opinions toward tailored health promotion strategies targeting African Americans were explored.



Cancer

Luo 2020 Government 12 China Information, Computing, and Communication Sciences; Medical and Health Sciences


This study aimed to discuss how to fully reveal the health information needs expressed by patients with hypertension in their questions in a web-based environment and how to use the internet to help patients with hypertension receive personalized health education.


Algorithm Hypertension

Mabuto 2017 Government 3 South Africa Medical and Health Sciences


We sought to describe how a strategy of interpersonal communication allows for precision health communication to influence behavior regarding care engagement.



HIV

Magadzire 2017

Non-governmental; International

4 Mozambique Not Supplied Government, Non-profit organisation

This study will assess the magnitude and causes of MOV (missed opportunities for vaccination) in three provinces that have received varying degrees of vaccine delivery strengthening interventions (e.g. optimized vaccine supply chain) and short-term interventions (e.g. immunization campaigns). This study will allow for some comparisons by province or type of barrier (e.g. vaccine shortages or other logistics barriers; the failure or inability of health providers to screen patients for eligibility; perceived contraindications to vaccination on the part of providers and parents).

Qualitative research, Protocol


Children vaccination



Marthick 2019 Not Supplied 6 Australia Medical and Health Sciences


This study aimed to explore the participant experience and perception of using an interactive Web-based portal for monitoring physical activity, remote symptom reporting, and delivering educational components.



Cancer

Martinsson 2018

Not Supplied 6 Sweden Information, Computing, and Communication Sciences; Medical and Health Sciences


We present an approach for predicting blood glucose levels for diabetics up to one hour into the future.


Algorithm Type-1 diabetes

McHugh 2012 Not Supplied 2 USA Information, Computing, and Communication Sciences; Medical and Health Sciences


This study aimed to evaluate the effects of a commercially available web-based tailored communication intervention on the health biometrics of overweight and obese employees 2 years after initial biometric collection.



Overweight, obesity

McPhee 2020 Non-governmental


Academia The primary objective of this study was to explore the effect of an individualized health-risk report intervention on changes in perceived disease risk in adults with CP (cerebral palsy). Secondary aims were to assess the relationship between health risk factors and perceived disease risk, and whether changes in perceived disease risk predict changes in PA (physical activity).

Case series Community/in-person program

Heart disease, diabetes, obesity

McReynolds 2019

Not Supplied 2 USA Medical and Health Sciences

Academia To review the current state of genomics and genetic testing in prostate cancer. DATA SOURCES: National guidelines, evidence-based summaries, peerreviewed studies, and Web sites. A case study is presented to illustrate key points.

Case report Diagnostic test Prostate cancer

Meng 2020 Institutional, Government

12 China Physical Sciences, Engineering and Technology

Academia Here, we present a textile-based sensor (TS) with greatly improved wearing comfort for practical and long-term continuous on-body biomonitoring.



Cardiovascular disease, obstructive sleep apnea-hypopnea syndrome

Mohan 2018 Non-governmental

12 India Medical and Health Sciences


This paper describes the design and methods of UDAY- A Comprehensive Diabetes and Hypertension Prevention and Management Program In India.

Case series, Protocol


Type 2 diabetes, hypertension

Moore 2019 Institutional, Government

9 USA Medical and Health Sciences; Behavioural and Cognitive Sciences; Philosophy and Religion

Academia We describe a program of research addressing the identification of brain biomarkers that differentially predict responses to two types of health information (analytic focused and emotion focused) designed to support optimal self-management of chronic conditions.



Mozafarinia 2020

Government 5 Canada Medical and Health Sciences


To develop a personalized health outcome profile as a feedback tool to improve self-management in people living with chronic conditions such as HIV and (2) to evaluate the interpretability and usefulness of the feedback tool for setting specific goals.



HIV

Nag 2018 Not supplied 6 USA Not Supplied Academia In this work we fuse multiple user created and open source data streams along with established biomedical domain knowledge to give two types of quantitative state estimates of cardiovascular health. First, we use wearable devices to calculate cardiorespiratory fitness (CRF), a known quantitative leading predictor of heart disease which is not routinely collected in clinical settings.





Nakamura 2018 Government 11 Japan Social Sciences, Humanities, and Arts (general); Medical and Health Sciences

Academia, Government, Health facility

We investigated whether 2 types of personalized health guidance (repeated and single counseling) in the Japanese nationwide cardiovascular prevention system promoted smoking cessation among smokers.



Smoking cessation

Nedungadi 2018

Not Supplied 3 India Information, Computing, and Communication Sciences; Commerce, Management, and Tourism Services

Academia This paper describes the concept of AmritaJeevanam, which aims to provide a one-of-a-kind healthcare platform that targets the needs of rural populations.



Not Supplied

New 2020 Institutional, Industry

2 USA Mathematical Sciences; Information, Computing, and Communication Sciences

Academia This class of study analyzes the association between one or more response condition(s) for us, bloodpressure and hypertension and many different environmental exposure risk factors, such as trace metals and pesticides. Using the SCM, we generalize existing environmental exposure risk analysis methods.


Algorithm Hypertension

Newman-Casey 2018

Government 7 USA Medical and Health Sciences

Academia This study was designed to pilot a personalized intervention that leverages these strategies (reminder systems and motivational interviewing (MI)-based counseling) to assess their impact on medication adherence in glaucoma patients.

Case series, Protocol


Glaucoma

Nishita 2011 Not Supplied 3 USA Medical and Health Sciences

Academia This study explores perceptions on the impact of diabetes on future independence and employment.



Type 2 Diabetes

Noar 2011 Institutional 5 USA Information, Computing, and Communication Sciences; Medical and Health Sciences


The purpose of the current investigation was to apply the attitude-social influence-efficacy (ASE) model to achieve a theory-based understanding of condom use among low income, heterosexually active African-American STD clinic patients.



Heterosexually active African-American STD clinic patients

Noble 2015 Institutional, Government



The aims of this study were to examine the acceptability and effectiveness of providing generic compared to tailored feedback on self-reported health risk behaviours among a high need sample of people attending an Aboriginal Community Controlled Health Service (ACCHS).



Cardiovascular disease, Type 2 Diabetes, Cancer

Oh 2014 Institutional 6 South Korea Medical and Health Sciences

Academia In this randomized controlled trial, we examined the effects of a 3-month therapeutic lifestyle modification (TLM) intervention on knowledge, self- efficacy, and health behaviors related to bone health in postmenopausal women in rural Korea



Osteoporosis

Page 2014 Not Supplied 4 USA Information, Computing, and Communication Sciences; Engineering and Technology

Academia In this paper, we aim at dealing with this challenge for the application of automated seizure detection. We explore the use of a variety of representations and machine learning algorithms to the particular task of seizure detection in high-resolution, multi-channel EEG data. In doing so, we explore the classification accuracy, computational complexity and memory requirements with a view toward understanding which approaches are most suitable.


Algorithm Seizure

Pak 2018 Government, Non-governmental

30 Burkina Faso, the Democratic Republic of the Congo, Ethiopia, Ghana,


Academia, Government, Non-profit organisation

The objective of the Health Population Africa (HPAfrica) study is to determine health behaviour and population-based factors, including socioeconomic, ethnographic, hygiene and sanitation factors, at sites of the Severe Typhoid Fever in Africa (SETA) programme.

Cross sectional study, Protocol

Algorithm Typhoid fever



Madagascar, Nigeria

Patel 2015 Institutional 5 USA Medical and Health Sciences

Health facility

The aim of this study is to explore patient and provider attitudes and interest in a proposed clinic-based tablet system for personal health information exchange. To provide a context to understand patients' use of tablets during their clinic visit, we also examine patients' current activities and time spent in the waiting room, and their use of health information resources.



Health in general

Paterno 2020 Government 3 USA Biological Sciences

Academia The purpose of this pilot, randomized controlledtrial was to determine the feasibility of recruitment (i.e., recruiting a 20% minority sample, most successfulrecruitment methods), retention, adherence, and data collection methods with a sample of pregnant women(n = 24) at 24 weeks gestation for a 12-week intervention using a PHM device.



Behaviour, sleep

Pathinarupothi 2019

Not Supplied 3 India Engineering and Technolog; Medical and Health Sciences

Academia We present an IoT-based smart edge system for remote health monitoring, in which wearable vital sensors transmit data into two novel software engines, namely rapid active summarization for effective prognosis (RASPRO) and criticality measure index (CMI) alerts, both of which we have implemented in the IoT smart edge.



Cardiac risk

Pethiyagoda 2016

Government, Industry

4 Not Supplied Biological Sciences; Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia This paper attempts to create a usable clinical decision support system (PEPCOR) that would help improve personalized health care and avoid unnecessary secondary, and costly, procedures that do not improve the care of a critically ill patient.

Case report Algorithm Hospital complications

Pleasant 2020 Government 3 USA Medical and Health Sciences

Industry In particular, a best practice of health literacy is the imperative to know your audience and tailor interventions to that audience. In this article, we focus upon formative research as a critically important method to achieve those ends.



Chronic disease prevention

Poorani 2018 Institutional 6 India Information, Computing, and Communication Sciences; Engineering and Technology

Academia This paper proposed a hybrid model NB3AkMGA for a personalized health care using machine learning methods and genetic algorithm



Popescu 2011 Institutional 2 USA Information, Computing, and Communication Sciences

Academia In this paper we compare the disease prediction based on crisp DRG features with the results obtained employing a new set of features that consist of the fuzzy membership of patient diagnoses in the DRG groups.


Algorithm Hypertension, diabetes mellitus, and coronary atherosclerosis

Pozaic 2013 Not Supplied 4 Croatia Information, Computing, and Communication Sciences; Engineering and Technology

Academia We have developed Wireless Body Area Network for continuous and personalized health monitoring of basic physiological parameters (ECG, breathing rate and body temperature) and added the functionality of mobility measurement and closed-loop assisted strength exercising.



Physical activity

Prichard 2015 Government 4 Australia Medical and Health Sciences; Behavioural and Cognitive Sciences


This quasi-experimental study aimed to determine whether a Family Health History (FHH) assessment and the subsequent provision of risk information would increase young adults' (17-29 years) intentions to modify health behaviours associated withthe risk of these chronic diseases (i.e. alcohol consumption, fruit and vegetable intake and physical activity) and to talk to their family about their risk.



Colorectal cancer, breast cancer, heart disease and diabetes



Qin 2018 Institutional, Government

2 China Chemical Sciences

Academia The present study, amied to investigate the potential application of Eu3+functionalized metal-organic frameworks for the effective detection of the 1-N in human urine.


Diagnostic test Neurological disorder, cancer

Qin 2019 Not Supplied 6 China Medical and Health Sciences

Health facility

To explore the influence of self-perceived burden, fatigue and negative emotions on the coronary atherosclerotic cardiopathy patients by the individualized health management.



Coronary atherosclerotic cardiopathy

Raat 2013 Government 10 The Netherlands

Medical and Health Sciences; Policy and Political Science


The aim of this study is to assess the effects of the two overweight prevention interventions with regard to child health behaviors and child Body Mass Index.



Overweight and obesity in early childhood

Rabbi 2015 Industry 4 USA Engineering and Technology

Academia This paper introduces MyBehavior, a smartphone application that takes a novel approach to generate deeply personalized health feedback.


Preventive health (weight loss)

Rapisarda 2013 Not Supplied 11 Italy Medical and Health Sciences

Academia The development of NHL among HCV-infected HCWs has recently been shown. To investigate this issue further a tailored health surveillance program was applied to 3,138 HCWs from four Medical Institutions.


Algorithm Non-Hodgkin lymphoma (NHL) among hepatitis C virus (HCV)-infected individuals

Reid 2018 Government 8 South Africa Medical and Health Sciences

Academia The current study aimed to develop a health dialogue model by applying a multiple-methods design informed by the United Kingdom Medical Research Councilâ€™s guidelines for the development and evaluation of complex interventions.



Type2 diabetes

Rezai 2019 Government 6 Canada Information, Computing, and Communication Sciences; Engineering and Technology; Medical and Health Sciences

Academia The goal of this study was to explore the impact of message tailoring, when tailoring was grounded in Higgins' Regulatory Fit Theory, and messages were constructed to promote physical activity.



Sedentary lifestyle

Rikard 2012 Institutional 5 USA Medical and Health Sciences


The present research describes a community and university project to develop a culturally tailored HIV/AIDS HL toolkit in the African American community



HIV/AIDS

Rosas 2020 Not Supplied 12 USA Medical and Health Sciences, Studies in Human Society

Academia, Industry, Government, Non-profit organisation

The goal of this study was to examine views from these groups about precision health and precision health research to inform strategies for conducting precision health research that will address health disparities.



Health disparities

Rosenberg 2016

None 10 USA Medical and Health Sciences

Health facility

The LIFE Cancer Survivorship Program at North Shore University Health System provides risk-adapted visits (RAV) facilitated by an oncology nurse during which a survivorship care plan (SCP) is provided and discussed. In this report, we describe and evaluate RAV in promoting individualized health care and self-management during survivorship transition


Transitional care for adult post-treatment cancer survivors

Rykov 2020 Government 7 Singapore Engineering and Technology; Medical and Health Sciences; Commerce, Management, and Tourism Services

Academia Thus, the objective of this study was to investigate the associations between different activity metrics retrievable from a consumer-grade fitness tracker and major modifiable biomarkers of cardiometabolic disease, relying on prolonged activity monitoring.



Cardiometabolic disease

Samaan 2013 Non-governmental


Academia Among at-risk South Asians living in Canada, our objectives are to determine: (1) the feasibility of a culturally tailored multimedia intervention to induce positive behavioral changes associated with reduced MI risk factors, and (2) the



Myocardial infarction



effectiveness and acceptability of information communicated by individualized MI and genetic risk score (GRS) reports.

Sant'anna 2014 Institutional 1 Sweden Information, Computing, and Communication Sciences

Academia In order to investigate this matter, we undertook a pilot study aimed at determining if and how activity monitoring can support person-centered care routines for patients undergoing total hip replacement surgery. This is a preliminary report describing the methodology, preliminary results, and some practical challenges.



Total hip replacement

Sastre 2019 Institutional 3 USA Medical and Health Sciences

Academia This project examined health behaviors of newly arrived immigrant and refugee youth through digital photography as part of a health promotion intervention.



Health promotion

Savage 2018 Government 8 Canada Medical and Health Sciences


We sought to understand how South Asian VFR (visit friends and relatives) travelers perceived and responded to travel-related health risks by conducting group interviews with 32 adult travelers from an ethnoculturally diverse Canadian region



Travel-related health risk

Schussler-FiorenzaRose 2019

Institutional, Government

30 USA Information, Computing, and Communication Sciences; Engineering and Technology; Medical and Health Sciences

Academia, Government, Health facility,

The study objectives were three-fold. We first evaluated the usefulness of emerging technologies in combination with standard and enhanced clinical tests to detect diseases early. We then characterized multi-omics associations with clinical pathophysiologies including glucose and insulin dysregulation, inflammation and cardiovascular risk; we also evaluated the ability of multi-omics measures to predict insulin resistance and response to glucose load. Last, we examined how participation affected health habits.

Cohort study Algorithm Type 2 diabetes

Sengupta 2019 Institutional 3 Not Supplied Engineering and Technology

Academia Herein, we report a sensitive, 3D squeezable graphene-polydimethylsiloxane (PDMS) foam-based piezo resistive sensor realized by infusing multilayered graphene nanoparticles into a sugar-scaffolded porous PDMS foam structure.



Gait characteristics as indicators for diseases such as Parkinsons, multiple sclerosis

Sim 2017 Institutional, Government

20 South Korea Information, Computing, and Communication Sciences; Medical and Health Sciences; Policy and Political Science


Finally, the aim of this study was to investigate the perceived need of cancer patients for ICT-based self-management programs and the association of this need with several sociodemographic variables and medical experience including information provision, decisional conflicts, and health-related quality of life (HRQOL).



Cancer

Simione 2020 Institutioanl, Government



The purpose of this study is to evaluate the psychometric properties of a modified version of the Family Centered-Care Assessment (mFCCA) tool and to assess the family-centeredness of two clinical-community childhood obesity interventions.



Childhood obesity

Smith 2020 Government 4 UK Medical and Health Sciences

Academia, Industry

This paper investigates whether DEMQOL and DEMQOL-Proxy can be placed on the same continuum and consequently whether a revised scoring algorithm, based on this equated model can be developed that takes account of the relationship between self- and proxy-reports.


Algorithm Dementia

Stewart 2019 Institutional 7 Not Supplied Medical and Health Sciences

Academia With interest in personalised health care growing, so is interest in personal genetic testing. This is now offered direct-to-consumer, thereby referred to as direct-to-consumer genetic testing (DTC-GT). Criticisms have been expressed on whether a truly informed decision to undergo testing is made with regard to these services. In order to provide relevant information to achieve this, knowing the characteristics of the expected user population is helpful. Therefore, the aim of this study is to identify characteristics of individuals who (1) find



Common chronic diseases



the concept of DTC-GT acceptable and (2) consider undergoing DTC-GT in the distant or near future.

Stewart 2018 Institutional 4 The Netherlands

Biological Sciences; Medical and Health Sciences

Academia The primary aim of the study is to study the effect of the Health Potential advice on change in lifestyle behaviour in distinguishable customer populations. The secondary aims are (1) to study the effect of the Health Potential service on determinants of behaviour change, (2) to study the effect of additional lifestyle counselling on behaviour change and determinants thereof, and (3) to study the characteristics of the Health Potential customer.

Randomised controlled trial, Non-randomised experimental study, Protocol


Not Supplied

Stienen 2015 Government 9 The Netherlands



This study evaluates an educational e-tool for patients with non-Hodgkin's lymphoma (NHL) designed to meet patient needs with respect to personalized and complete health-related information provision. The e-tool aims to help NHL patients manage and understand their personal care pathway, by providing them with insight into their own care pathway, the possibility to keep a diary, and structured health-related information.



Non-Hodgkin's lymphoma

Stolee 2012 Not Supplied 7 Canada Medical and Health Sciences; Studies in Human Society


To assess the feasibility and utility of GAS in a multi-site study of six GDH affiliated with the Regional Geriatric Programmes of Ontario.

Cross sectional study Cross sectional study


Geriatric care for people with co-morbid chronic medical conditions

Sturm 2018 Institutional, Government, Non-governmental


Academia We examined patient preferences in the context of use of a post-test genomic counseling framework on patients (n = 44) with chronic disease receiving online test reports for eight different diseases and one drug-response result. We also explored patients’ disease risk awareness, recall of test report information, and confidence in knowing what to do with their test results.

Cross sectional study Cross sectional study


Genetic disease

Sullivan 2020 Institutional, Government

3 USA Engineering and Technology; Medical and Health Sciences

Academia This study examines the prognostic ability of 12- and 24-month mortality risk reflected in the OASIS-SQ and develops an alternative approach for classifying mortality risk to support decision-making in the absence of the OASIS-SQ.


Mortality risk

Sun 2019 Government 5 China Medical and Health Sciences


To investigate the application of self-care based on full-course individualized health education (FCIHE) and its influencing factors in patients with chronic heart failure (CHF).




Sztyler 2015 Government, International

5 Not Supplied Engineering and Technology

Academia We want to develop an application which monitors the personal lifestyle of the users and provides appropriate visualizations. However, this still needs a sufficient acceptance because the user has to view and interpret the visualizations. Therefore, we also want to provide automatically generated recommendations resulting from the monitoring data and, e.g., references (practical guidance). In the long term, we also have to automatically recognize a persona's daily activities such as different types of sports and desk work. This is necessary to ensure that the required user input is a minimum which also is a requirement to make the application practical.



Not Supplied

Tabatabaei 2018

Not Supplied 3 Not Applicable

Information, Computing, and Communication Sciences

Academia Because of its focus on finding suitable actions/interventions that lead to long term rewards, reinforcement learning is very suitable for personalization but requires a substantial learning period. To overcome this so-called cold start problem, we propose a novel approach called narrowing reinforcement learning.


Algorithm Physical activity



Takahashi 2014 Government, Non-governmental

20 Japan Biological Sciences; Medical and Health Sciences


Therefore, in a previous study, we proposed a combined method consisting of a knowledge-based algorithm, 2 stages of screening, and a permutation test for identifying SNPs. In the present study, we applied this method to a pharmacogenomics study where 109,365 SNPs were genotyped using Illumina Human-1 BeadChip in 168 cancer patients treated with irinotecan chemotherapy.



Tampubolon 2018

Not Supplied 2 Indonesia Medical and Health Sciences

Academia In this study, the author analyzed the outcome of skin tissue repair dorsal-slit and laser (cauterization) through expression of tenascin-C. (TNC) is an extracellular glycoprotein expressed during embryogenesis and markedly increased in wound healing, especially in resolution phase.


Diagnostic test Would healing

Taualii 2014 Government 7 USA Medical and Health Sciences


This study explored Native Hawaiian perceptions of and expectations for biobanking.



Cancer

Taylor 2018 Government 5 USA Information, Computing, and Communication Sciences; Medical and Health Sciences


The objective of this qualitative study is to describe the health information work of FF (family and friends) in the context of OA (older adults) PHIM, identify barriers that stand in the way of that support, and offer design recommendations for supportive HIT.



Older adults' personal health information management

Thiel 2011 Institutional, Government

8 Germany Medical and Health Sciences


The GOAL Study (German Young Olympic Athletes' Lifestyle and Health Management Study) analyzes the individual and organizational management of health in adolescent elite sports.



Health promotion

Thompson 2017

Institutional 5 USA Medical and Health Sciences

Academia This study aimed to understand how relationship status and vaccination status impact risk perceptions and perceived need for the HPV vaccine among young adult women.



HPV

Truong 2020 Government 7 UK Science (general); Agriculture, Veterinary, and Environmental Sciences; Medical and Health Sciences

Academia Here, we use UK Biobank data and show an efficient polygenic prediction when we use relatives in a PRS approach to predict phenotypes of complex traits


Algorithm mental, physical and lifestyle traits

Tseng 2018 Government 4 Taiwan Information, Computing, and Communication Sciences

Academia In this work, we aim to build a big data analytics framework for sports behavior mining and personalized health services. We analyzed users' exercise data including heart rate and GPS data, which were collected in a practical sports and social platform, to discover users' periodic sports patterns and the trend of heart rate change during exercise.


Algorithm Health and wellness

Tucker 2016 None 8 USA Medical and Health Sciences


The primary purpose of this study was to explore the feasibility, preliminary effects, and barriers and facilitators of integrating a 6-month worksite NEAT+ PA intervention, with personalized health coaching via text messaging, into the workflow of ambulatory clinic nursing staff (RNs and MAs).


Physical inactivity

Turner 2014 Not Supplied 4 USA Information, Computing, and Communication Sciences

Academia In this study we consider the problem of detecting whether a patient is having a seizure or not based upon the patients EEG readings for any given second, and how those readings differ from a baseline that is standardized from either the patient's EEG history or other patient's EEG readings.


Algorithm Seizures

vandenBrekel-Dijkstra 2016

Government 5 The Netherlands



The aim of this pilot study is to evaluate feasibility and the effectiveness of a personalized prevention approach with use of a web-based cardiovascular risk assessment with tailored lifestyle follow-up.

Case series Individual digital health promotion tool


vandenBroek 2017

Government 9 Not Supplied Medical and Health Sciences

Industry Industry

We describe the first application of VAMS with the Mitra microsampling device for the quantification of protein


Diagnostic test Monitoring



biomarkers using an automated, high-throughput sample preparation method coupled with mass spectrometric (MS) detection.

vandenBroek 2017

Government, Industry, International

8 The Netherlands

Science (general) Industry Industry

This study aims to demonstrate that quantification of PFT response can discriminate between different states of health within the healthy range of the population.

Cohort study Diagnostic test Metabolic health

vanDongen 2019



Academia The objective of the study is to monitor the capacity-building processes of the FLASH intervention, including the design and implementation of health-promotion activities by each school community, and to explore if these processes contribute to changes in community capacity. In addition, we will explore if the FLASH intervention relates to changes is PA, dietary behaviours (including determinants of PA and dietary behaviours) and BMI of students. This paper provides a description of the study design.

Protocol, Non-randomised experimental study


Physical inactivity, diet, overweight.

vanLimpt 2011 Non-governmental

9 The Netherlands

Mathematical Sciences; Medical and Health Sciences


To determine in primary care patients at high risk for a cardiovascular event, the effects on biomedical risk factors for and incidence of cardiovascular events, of a brief cardiovascular prevention program executed by a health advisor



Cardiovascular disease or diabetes

vanOs 2017 Government, Non-governmental, International

18 The Netherlands

Medical and Health Sciences; Behavioural and Cognitive Sciences


Multiple examples of ESM (experience sampling method) data collections across different patient groups and settings are shown and discussed, varying from an ESM evaluation of a 6-week randomized trial of mindfulness, to a twin study on emotion dynamics in daily life.



Psychotic disorder, depression, residual depression

Vaughn 2019 Government 4 USA Medical and Health Sciences


To present a study protocol to explore feasibility, acceptability and, usability of integrating mobile health technologies to collect and monitor symptom data for pediatric blood and bone marrow transplant (PBMT) patients.

Protocol, Technology/tool testing


Pediatric blood and marrow transplant patients

Vela 2019 Government 4 USA Information, Computing, and Communication Sciences; Engineering and Technology; Medical and Health Sciences

Academia Here, we describe Zik, a standalone bioimpedance analyzer with Internet of Things (IoT) monitoring features. Zi k can be connected to a secure wireless or local area network and accessed using any device with a Web browser and Internet access. Through a user-friendly Web-based access able to handle multiple simultaneous connections, the user(s) can perform single or multiple bioimpedance measurement(s) remotely.



Vilaro 2017 Government 8 USA Not Supplied Academia Thus, the purpose of this article is to describe the development and preliminary testing of the Food Choice Priorities Survey (FCPS), which is designed to identify the factors having the greatest effect on the food choices of college students.


survey development

Food choice

Vosbergen 2015


Information, Computing, and Communication Sciences; Medical and Health Sciences


The aim of this study was to develop a method for tailoring health education messages to patients' preferences for message features using the concept of personas. This is a preliminary study focused on education for CHD patients.



Coronary heart disease

Wahbi 2018 Not Supplied 20 France Medical and Health Sciences

Academia This paper focuses on the development of the MI (motivational interviewing) intervention delivered by telephone to one-third of the study sample. The purpose of the original longitudinal randomized controlled trial, from which this report is drawn, is to assess the efficacy of two separate interventions designed to increase colorectal screening test use when compared to a usual care, control group

Cohort study Cohort Study

Algorithm Dystrophy type 1

Wang 2016 Not Supplied 5 Not Supplied Information, Computing, and

Academia Therefore, this study integrates mobile devices, context-aware technology, and collaborative recommendation algorithms to


Algorithm Health and wellness



Communication Sciences

develop a health care system. The major application of this system is as a daily health care information recommendation service. The target subjects are young people. It is hoped to assist users of this system to pay more attention to preventive health care and health self-management.

Weijers 2018 Not Supplied 3 The Netherlands


Academia The aim of this study of the 3600Child-profile was to investigate the inter- and intra-rater reliability and concurrent validity in a population of CYHC-medical doctors (MD's) to estimate overall- and psychosocial functioning and needed intervention.


Algorithm Children's health/functioning

Wheeler 2018 None 2 USA Medical and Health Sciences

Academia The primary aim of this study was to gain a richer understanding of the lived experiences of adults living with CS (Crouzon Syndrome) and to identify perceived biopsychosocial and socioecological factors that affect perceived QOL (quality of life) among this population.



Crouzen Syndrome

Williams 2019 Government, Industry, Non-governmental


Academia, Industry, Government

Here, we show that plasma protein expression patterns strongly encode for multiple different health states, future disease risks and lifestyle behaviors.


Diagnostic test Future metabolic health risk

Xia 2010 Government 18 China Medical and Health Sciences


The ADACS (Anti-tuberculosis Drugs induced Adverse Reactions in China National Tuberculosis Prevention and Control Scheme Study) aimed to explore ADRs' (adverse reactions) incidences, prognoses, economical and public health impacts for TB (tuberculosis) patients and TB control, and build a DNA bank of TB patients.

Cross sectional study, Case control study, Protocol

Algorithm Tuberculosis

Xiao 2019 Not Supplied 6 USA Information, Computing, and Communication Sciences; Medical and Health Sciences

Academia, Industry

To address such challenges, we develop an integrated framework that unifies dynamic modeling, sparse learning, dictionary learning and matrix completion to translate users' behavioral data into personalized dynamic system models and use them as constraints for deriving deeply personalized longitudinal health plans. We evaluate the proposed framework on a real-world user behavioral dataset and demonstrate its promising utility and efficacy.


Algorithm Health promotion

Yang 2013 Institutional 5 USA Medical and Health Sciences

Academia, Industry

Here we provide a case review of a participant who completed the PHP-IHC intervention.

Case report Community/in-person program

Excess weight during pregnancy

Youm 2017 Not Supplied 2 Korea Information, Computing, and Communication Sciences

Academia The objectives of this study were to evaluate the effectiveness of home healthcare products and multimedia software, and suggest ways to stimulate their use by analyzing the effect of a consistent awareness of one's health status on the change in one's exercise habits and health-improvement activities.



Physical activity

Zang 2017 Government 5 China Physical Sciences Academia In this study, we designed and fabricated a facile, portable radial artery pulse sensor using a flexible and stretchable graphene-coated fiber.




Zhou 2010

Not Supplied 6 China Medical and Health Sciences

Academia A randomized cluster trial was conducted to assess the impact of individualized health intervention guided by the transtheoretical model (TTM) theory on behavior change and quality of life (QoL) among the older rural population of China.



Health risk behaviours

Zhu 2017 Government 6 China Engineering and Technology; Medical and Health Sciences

Academia In order to solve this problem, this paper summarizes the current situation and problems of risk prediction relevant to the readmission for patients.


Algorithm Cardiovascular disease



Appendix 4b. Characteristics of samples/participants and details on precision and personalisation in the reviewed studies (n=225)

SAMPLE CHARACTERISTICS PRECISION ELEMENTS

First author

and year of

publication

Participant

health status

Actual health

condition of

participants at-

risk/with an

acute or

chronic illness

Age

(mean/

median;

years)

Age

(standard

deviation/

Interquarti

le range;

years)

Age

range

(years)

Sample

size

Percentage

of female

participants

Percentage

of non-

Caucasian

participants

Included

participants

with socio-

economic

disadvantage

Sentence in the body defining

precision health

Precision

Health

Category (most

representative;

Gambhir 2018)

Type of data used

for the

tailoring/personalis

ation component

Abbott 2018 Explicit "recruitment" of healthy populations, At-risk/pre-clinical disease stage, With chronic illness

Pre-diabetes, diabetes, heart disease

59 12.9 >= 24 229 71.18 100 Yes Developing such tailored health programs for specifically targeted groups can be facilitated by considering the moderators of intervention effects that were determined from previous studies (MacKinnon, 2011).

Intervention Sociodemographic/ economic, Psychological/ psychiatric, Diet/ nutritional

Adams 2014 No mention of health condition

Not Applicable Not Supplied

Not Supplied

Not Supplied

946 Not Supplied/ Applicable

Not Supplied/ Applicable

No Computer tailored health communications (CTHC) systems aim to elicit healthy behavior changes by sending motivational messages personalized to individual patients. Cur- rent CTHC systems start by creating a pool of messages and a fixed set of theory-driven, expert-written rules that relate the characteristics of messages to the characteristics of the patients [4].

Data analytics Perspective/ opinion/ usage

Afzal 2018 Explicit "recruitment" of healthy populations


Not Supplied

25 - 49 40 25 Not Supplied/ Applicable

No Mining Minds platform consists of an array of innovative services, tools, and techniques, working collaboratively to investigate human's daily life data, generated from heterogeneous resources, for personalized health and wellness support (Banos et al., 2016).

Data analytics Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity, Socio-environmental

Ahmed 2015 No mention of health condition


Not Supplied

Not Supplied



No 1.1. System for Personalized Health Monitoring. The steps in process diagram of the proposed system for personalized health monitoring service are presented in Figure 1. As can be seen, the proposed system started from sensor signals as Step1, there are five different sensor devices that are sending measurements for five different health parameters of a user i.e., 1) Blood Pressure (BP), 2) Blood Glucose (BG), 3) Weight (WGT), 4) Activity (AC) and 5) Pulse Rate (PR).

Data analytics Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Ahola 2013 At-risk/pre-clinical disease stage, With acute illness

Wide range of psychosocial problems

18 Not Supplied

Not Supplied

1280 0 Not Supplied/ Applicable

Yes Tailored health communication has proved to be an effective method in promoting healthy behaviours [20, 21], but has not been utilized in activation interventions among youth.

Intervention Anthropometric, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric



Almeida 2020 At-risk/pre-clinical disease stage

Prediabetes Not Applicable

Not Applicable

>= 19 years



No The digital DPP is a technology-enabled translation of the DPP lifestyle intervention [3] that consists of small group support, personalized health coaching, digital tracking tools, and weekly behavior change curriculum approved by the CDC Diabetes Prevention Re-cognition Program (the Omada Health Program).

Intervention Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

An 2013 No mention of health condition

Not Applicable

24.07 Not Supplied

18 - 30 years

1698 72.44 26.09 No The tailored health message group targeted four behaviors as part of a general wellness-framed Web site: cigarette smoking, alcohol use, exercise, and eating breakfast.'

Intervention Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Anderson 2015

With chronic illness

Breast cancer, with at least one moderate-severe menopausal symptom

49.2 6.2 Not Supplied


No The nurses outlined the 12-week program, provided tailored health education, and assisted with individual goal setting for exercise, healthy eating, smoking, and alcohol consumption.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

AntOzok 2014

Explicit "recruitment" of healthy populations


Not Supplied

>= 21 22 50 Not Supplied/ Applicable

No More individualized and tailored health information for patients with different illnesses and education levels

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Archibald 2011

No mention of health condition


Not Supplied

35 - 45 4 Not Supplied/ Applicable

100 Yes The purpose of this study was to discover from interviews, ways to tailor health care interventions to fit the cultural identity of a minority group of people in order to reduce health disparity.

Risk assessment Perspective/ opinion/ usage

Arens 2018 With chronic illness

Metabolic syndrome

49.6 9.3 35 - 60 166 59.04 Not Supplied/ Applicable

No Primary mission of this study of personalized health management in metabolic syndrome patients was to observe whether personalized digital feedback through the HCP would enhance the success rate of weight reduction relative to usual care.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Atack 2012 No mention of health condition


Not Supplied

21 - 69 57 31.58 26.32 Yes We anticipate that Internet access and the ability to tailor health materials will promote health education for all, but in particular for those who face traditional

Intervention Not Applicable



barriers related to literacy, education and geography.

Atzmueller 2018


Parkinson's disease

Not Supplied

Not Supplied

Not Supplied



No We showed the efficacy of the proposed approach in an evaluation using two real-world datasets: (i) In the context of personalized health using wearable sensors, and (ii) for activity recognition using smartphones.

Risk assessment Behavioural/ lifestyle/ physical activity

Avery 2019 With chronic illness

Cancer-related major abdominal surgery

61.7 12.6 27 - 81 61 42.62 1.64 No Finally, making routinely collected ePRO (electronic patient reported outcomes) data available to clinicians through its integration into patients' electronic health records (EHR) has the potential to advance precision health and patient-centred care [24] by enabling ePRO data to be considered alongside other clinical data to better plan appropriate care, to inform patient-clinician encounters and to improve shared clinical decision-making

Data analytics Sociodemographic/ economic, Perspective/ opinion/ usage, Self-reported symptoms of adverse effects

Ayres 2013 At-risk/pre-clinical disease stage

Elevated cholesterol level


292 71.23 Not Supplied/ Applicable

No A tailored health plan can include dietary and lifestyle changes that are tailored to helping you improve the health of your heart.

Intervention Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity, Diet/ nutritional,

Badawi 2012 Explicit "recruitment" of healthy populations


Not Supplied

Not Supplied


No In this paper, we proposed a personalized health advisory system for children based on real-time biofeedback sensors to provide accurate and up-to-date decisions about children's food, clothing, and activities using electronics child record, as the health profile for each child, and ontologies for both vitamins and allergies as knowledge base system to support the decision making

Intervention Perspective/ opinion/ usage

Bannink 2012 No mention of health condition


Not Supplied

15 - 16 Not Supplied



No Computer-tailored health education is a good opportunity to provide health messages regarding individual health behaviour and behavioural determinants, because tailored messages eliminate (as far as possible) information that is not personally relevant [15-18].

Intervention Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Bariya 2018 No mention of health condition


Not Supplied

Not Supplied



No We demonstrate high throughput fabrication across large swathes of flexible substrate, enabling inexpensive, large-scale production of disposable sensing components for wearable hybrid electronics with a view to making personalized health monitoring at molecular levels accessible to the broader community.

Customized monitoring

Physiologic/ biochemical/ clinical



Barnes 2020 With chronic illness

Stroke 69 Not Supplied

Not Supplied

196 46.94 10.20 No For well over a decade, personalized health, or more recently, precision medicine,1 has been widely viewed as the solution to improving the efficacy of medical therapies through individualized, targeted treatments.


Barron 2013 With chronic illness

Chronic obstructive pulmonary disease, congestive heart failure

76.4 Not Supplied

66 - 84 7 42.86 14.29 No Johns Hopkins Medicine is currently introducing a new patient portal to provide personalized health information.


Bassett 2011 With chronic illness

Spinal cord injury



No Alternatively, individualized health information is objective risk information that is specific to the recipient, such as: Your waist circumference is 110 cm. People with a waist circumference greater than 102 cm are at risk for type 2 diabetes.

Intervention Anthropometric, Physiologic/ biochemical/ clinical

Batool 2012 No mention of health condition

Not Supplied Not Supplied

Not Supplied

Not Supplied

Not Supplied



No The proposed system monitors changing health conditions, emotions and interests of users to provide real time personalized health information and guidance from highly qualified physician's knowledge.

Data analytics Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Psychological/ psychiatric

Bazdarevic 2015


Not Applicable 25.8 Not Supplied

Not Supplied


No This paper, therefore, investigates the relations with emotions from multiple perspectives - their effect on personalisation needs and re-usage intentions, as well as the effect of usage of a personalised health website on the emotional state.

Intervention Sociodemographic/ economic, Perspective/ opinion/ usage, Psychological/ psychiatric

Beckmann 2018



Not Supplied

Not Supplied



No We address the above named issue by developing a generic medical sensor framework which is able to combine sensors and collect data independent of devices. Through this solution we make sensor fusion generic, thus enable personalized health needs and the usage of desired sensors.


Perspective/ opinion/ usage

Berks 2019 With acute illness

Women with pregnancies complicated by preeclampsia, fetal growth restriction and/or gestational diabetes mellitus

31.6 4.2 >= 18 206 100 Not Supplied/ Applicable

No The computer-tailored health education program and the three questionnaires were completed by the participants before each counselling session.

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Bidargaddi 2018



Not Supplied

Not Supplied


No The app sends time-varying push notifications containing tailored health messages to provide feedback related to behavior modification and to encourage interaction with the app.

Intervention Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Diet/



nutritional, Socio-environmental

Blake 2018 At-risk/pre-clinical disease stage

At risk of HIV (workplaces selected for having a high proportion of employees from sub-Saharan Africa)

Not Supplied

Not Supplied

>= 18 806 46.53 14.27 Yes The events included on-the-spot tailored health advice, and take-away resources (e.g. condoms and leaflets on safer sex). Advice was tailored according to test results and included discussion and signposting around HIV testing and services, sexual health and healthy lifestyle behaviours.

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental

Blake-Lamb 2018



Not Supplied

Not Supplied

Not Supplied


Yes First 1000 Days Patient Navigators use the results to connect patients and partners to individualized health information, health center programs, and community resources.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Diet/ nutritional, Socio-environmental

Borbolla 2014



Not Supplied

Not Supplied

Not Supplied



No From tethered PHRs (personal health records), patients can have access to their problem list, medication list, laboratory test results, and links to personalized health information.


Bosak 2018 Explicit "recruitment" of healthy populations

Not Applicable 52 Not Supplied

44 - 64 43 100 4.65 No The Precision Health Initiative emphasizing individualized healthcare is leading the discovery of novel biomarkers.



Braun 2014 With chronic illness

Heart disease 67 10.5 Not Supplied


No The current ICWP has been extended to include, in addition to the metabolic supplements, ward visits by naturopaths to enable patients to receive individualised health promotion recommendations and learn more about their health and cardiac risk factors.

Intervention Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

Brown 2016 With chronic illness

Cancer Not Applicable

Not Applicable

>= 21 357 Not Supplied/ Applicable

100 No One communication method that has demonstrated efficacy to promote patient activation (characterised by asking questions, expressing concerns and being assertive) in consultation communication is providing tailored health messages (THM). THM increase the relevance of health information by targeting individuals’ personalised needs based on a rigorous assessment of their characteristics and preferences and have been successfully used to promote AA cancer screening behaviours.

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Socio-environmental



Brown 2019 Explicit "recruitment" of healthy populations

Not Applicable 28.9 3.07 25 - 55 338 100 Not Supplied/ Applicable

No Few prior studies have elucidated the screening barriers and facilitators predicting women's screening attendance, upon which tailored health promotion strategies could be based (Sadler et al., 2013).

Risk assessment Sociodemographic/ economic, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental

Cappelletti 2014

At-risk/pre-clinical disease stage

At risk of cancer 42.2 13.3 19 - 86 372 84.68 58.87 Yes These findings suggest a plausible pathway through which unmet basic needs in vulnerable populations may interfere with the effects of tailored health behavior interventions

Intervention Sociodemographic/ economic, Socio-environmental

Chang 2015 With chronic illness

Stroke 74.47 4.64 61 - 74 19 47.37 100 No In addition to the usual ADC services, our intervention program incorporated two new key components: (1) family involvement in the elderly stroke patients’ care and (2) patient-tailored health management, both of which were developed from previous research findings in which family involvement and health management improved health and psychological outcomes of the elderly or their caregivers.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental

Chen 2017 With acute illness, With chronic illness

Outpatient visits, with a condition in any of the 21 diseases in the ICD-10 manual

Not Supplied

Not Supplied

Not Supplied



No Personalized health advices are further provided for individuals based on risk estimates.

Data analytics Physiologic/ biochemical/ clinical, Socio-environmental

Chen 2019 With chronic illness

Congenital heart disease


Yes The development of tailored health consulting interventions to fulfill healthcare needs is required to improve physical and psychosocial wellness among youths with CHD. (identical to sentence in abstract, and no other use of the term)

Risk assessment Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Chen 2018 With chronic illness



No By assessing disease related knowledge of patients with CAD, healthcare professionals can develop tailored health education and evaluate the effectiveness of the intervention. Therefore, it is essential to have a suitable tool to measure disease-related knowledge for patients with CAD.


Chiang 2019 No mention of health condition


Not Supplied


No We also provide early validation of the effects of personalized health behavior recommendations suggested by the proposed RFFS model.

Data analytics Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity



Chua 2011 No mention of health condition

Not Applicable 37.5 11.5 21 - 55 91 48.35 Not Supplied/ Applicable

No FROM SUPPLEMENTARY METHODS: We based the Tailored and Untailored messages on cognitive-behavioral methods of smoking cessation and relapse prevention1. Tailored statements include self-relevant personalization and feedback about the smoker. It involves the degree to which there are recognizable features of the individual in the message (e.g., You have been smoking for 12 years), as well as references to the individual's state characteristics (e.g., levels of stress and coping) which were generated based on participants' responses.

Intervention Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Colkesen 2011



45 7.8 Not Supplied


No By a computer-based combination of the risk profiles with health-behavior concepts, individually tailored health advice was generated.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Diet/ nutritional, Psychological/ psychiatric

Cortese 2012 No mention of health condition

Not Applicable 13.93 1.03 13 - 17 151 56.95 60.93 No This study evaluates a tailored health education site designed to help teens learn about sexual health and decision making. As a health education approach, tailoring involves the creation of customized messages and feedback that consider factors that may influence an individual's health behaviors.

Intervention Sociodemographic/ economic, Psychological/ psychiatric, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Socio-environmental

Cote 2015 With chronic illness

HIV Not Applicable

Not Applicable



No Until now, most of the studies testing the efficacy of Web-based tailored health behaviour change interventions have been designed and conducted among the general population, were more preventive in nature and did not involve support for complex tasks required in self-management of chronic conditions (Lustria et al., 2013).

Intervention Psychological/ psychiatric

Crosby 2015 With chronic illness

Sickle cell disease

16 2.3 12 - 20 30 50 100 No They also worked with families to develop an individualized health plan and an emergency plan. At the end of the academic year, study participants showed an improvement in quality of life (as measured by the Pediatric Quality of Life Inventory; Varni, Seid, & Kurtin, 2001), grades, participation in classroom and extracurricular activities, and disease management (knowledge,

Risk assessment Sociodemographic/ economic, Perspective/ opinion/ usage



skills and confidence to manage a chronic disease).

D'Addario 2020


Acute coronary syndrome or hypertension

Not Applicable

Not Applicable



No The 'Time to Change Your Behavior' (TTCYB) is a randomized controlled intervention that uses tailored health print educational material to improve healthy lifestyle behaviors (dietary behavior, physical activity, alcohol intake and smoking behavior) in patients affected by acute coronary syndrome (ACS) or essential hypertension.

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

DeGagne 2015


Not Applicable 50.45 7.15 40 - 64 125 43.2 100 Yes The participants in the focus group expressed strong feelings about needs for health support system: (a) self-management demands, (b) community based health programs, and (c) culturally tailored health care services.

Risk assessment Sociodemographic/ economic, Perspective/ opinion/ usage, Socio-environmental

deSoutoBarreto 2014


Seasonal influenza

86 8.2 Not Supplied


No ...And the presence of an individualised health care project (i.e., care project specifically designed for one subject as the result of a multidisciplinary work developed to establish feasible strategies to delay the onset/progression of the resident's negative health outcomes).

Risk assessment Not Applicable

deVries 2012 With chronic illness

Skin cancer 46.2 Not Supplied

Not Supplied


Yes Computer tailoring developed even before the Internet period fosters the development of highly individualized health communication messages that match each person's unique conditions, characteristics, motivational beliefs (such as knowledge, attitudes, and self-efficacy), and intentions to change and behavior.

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Devaux 2016 With chronic illness

Cardiac arrest 63 12 20 - 94 579 19.69 Not Supplied/ Applicable

No In the cardiovascular field, miRNot Applicables have been identified as potential novel tools for personalized health care of patients with heart disease such as myocardial infarction.

Risk assessment Physiologic/ biochemical/ clinical

Donovan 2012


Not Applicable 21.41 1.74 18 - 25 62 59.68 25.81 No The current study tested the feasibility of an online, tailored health program for community college students. Specifically, a prototype of the website was designed for traditional-aged community college students, as they are a group at high risk for substance use problems (SAMHSA, 2011). Feasibility testing was approached with a four-phase design. First, we conducted a needs assessment to determine the content themes and program features that students and practitioners perceived to be relevant and important.

Intervention Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental



Doove 2016 At-risk/pre-clinical disease stage

Substance abuse 32.4 9.7 Not Supplied

423 33.33 28.13 No Beyond an assignment to universally best treatments, nowadays much importance is attached to personalized health, that is, to the fact that persons should receive the treatment that is optimal given their individual characteristics (Tunis, Benner, & McClellan, 2010). Personalized health is rooted in the idea that relative treatment effectiveness may vary over subgroups of clients (defined in terms of person pre-treatment characteristics, which are also called moderator variables).

Data analytics Sociodemographic/ economic, Physiologic/ biochemical/ clinical

DosSantos 2020



Yes As a matter of fact, human development and health behaviours are strongly affected by different types of social factors, at the individual, family, community, and national levels [7]. Therefore, the understanding of these behavioural clusters and its relationship with individual and contextual factors is of extreme use to Public Health, allowing tailored health-promoting interventions [8].

Intervention Behavioural/ lifestyle/ physical activity

Doyle 2014 No mention of health condition

Not Supplied 70.6 4.13 65 - 77 7 28.57 Not Supplied/ Applicable

No We consider our main contribution to be an increased understanding of older adults' attitudes and behaviours in relation to wellbeing self-management and factors that affect acceptance and adoption of such, that can facilitate the creation of new, personalized health and wellbeing interventions for this population

Intervention Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental

Drake 2018 With chronic illness

Type 2 diabetes 59.4 10.5 Not Supplied

19 68.42 78.95 No This study adapted personalized health planning (PHP), an evidence-based intervention designed to engage patients in creating and achieving meaningful personal health-related goals, to be delivered within shared medical appointments (SMAs).

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

Dreer 2016 With chronic illness

Glaucoma 61 7.02 Not Supplied

11 72.73 100 No Thus, in order to reduce the health disparity gap in glaucoma medication adherence, there is a demand for culturally and individually tailored health promotion programs that are designed to meet the needs of AA's living with glaucoma

Intervention Perspective/ opinion/ usage, Socio-environmental



Drost 2020 At-risk/pre-clinical disease stage

Lynch syndrome

Not Supplied

Not Supplied

Not Supplied



No Missense variants comprise a significant fraction of the genetic variants identified in the MMR genes, particularly in MSH6.3 In case such a variant cannot be classified as (likely) pathogenic or (likely) non-pathogenic, personalized health care for affected families cannot be implemented.

Data analytics Genetic/ genomic

Drozdovska 2020



Not Supplied


No These results suggest that PPARG genotyping can be used to personalize health-promoting fitness programs. The data of genetic status and morphofunctional parameters assessment were used to develop aerobic and resistance training fitness programs for young women with Pro/Pro, Pro/Ala, and Ala/Ala genotypes of REG1, REG2, AEG2, and AEG2 subgroups

Risk assessment Anthropometric, Physiologic/ biochemical/ clinical, Genetic/ genomic, Behavioural/ lifestyle/ physical activity

Elbert 2016 No mention of health condition


No First, we aim to answer the question whether a tailored health intervention delivered via a mobile phone app is able to change fruit and vegetable intake in the advocated direction. Second, this study provides an exploratory test of the possible difference in efficacy between the more classic textual mode of communication (reading) and the auditory mode of communication (listening).


Engel 2014 Explicit "recruitment" of healthy populations, With chronic illness

Inborn errors of metabolism (rare genetic disease)

Not Supplied

Not Supplied


No Three additional future development lines can be defined for SHM: (1) connection of SHM output to a disease database, (2) development of personalized health control, and (3) application of SHM in clinical trials.


Enwald 2015 Explicit "recruitment" of healthy populations


Not Supplied


No It has been argued that the differences in individuals' health information behaviour should be used as a basis to tailor health information and communication (for example, Fourie 2008, Harland and Bath 2008, Ek and Heinstrm 2011, Johnson and Case 2012: 207, Enwald 2013: 119-133). Tailored health communication is a means to increase the effectiveness of health information by providing more user-centred information. It aims to increase the possibility that the information content is received, processed and accepted by the receiver. (Kreuter 1999: 5, Hawkins 2008.




Enwald 2013 At-risk/pre-clinical disease stage

Prediabetes Not Supplied

Not Supplied

Not Supplied


No Tailoring of health communication could increase the possibility that the information content is processed and accepted by the receiver to enhance healthy behaviour. Even minor differences in an individual's reception of the content of information should be given attention when planning tailored health communication. It has been stated that the reasons behind individual differences in health information behaviour should be taken into consideration in tailoring health information for information services (Ek and HeinstrÃ¶m 2011; Bar-Ilan et al. 2006; Fourie 2008).


Enwald 2012 At-risk/pre-clinical disease stage

Prediabetes Not Supplied

Not Supplied

Not Supplied


No Rimer and Kreuter state that tailored health communication is any combination of information and behaviour change strategies intended to reach one specific person based on information unique to that person, related to the outcome of interest, and derived from an individual assessment.

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Fadhil 2019 Explicit "recruitment" of healthy populations


No The approach focuses on providing tailored health activities that adhere to users' preferences. This is achieved by the human “conversational agent mediated coaching which provides a structured health plan to users after analyzing their conversation data with the conversational agent.

Intervention Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity

Fan 2015 No mention of health condition


Not Supplied

Not Supplied



No We also extend this model based on covariates, introducing associated parameter heterogeneity, and apply it to personalized health data given via wearable equipment


Fan 2019 No mention of health condition

Not Applicable 76 7.8 Not Supplied


No Yu et al. [3] proposed a personalized healthcare monitoring platform to forecast one-day-forward wellness conditions for elderly.

Data analytics Physiologic/ biochemical/ clinical, Psychological/ psychiatric

Faro 2019 At-risk/pre-clinical disease stage

Smokers Not Applicable

Not Applicable

> 18 600 Not Supplied/ Applicable


No Because of feedback from PCORI and peer review, we expanded our study to also test the effectiveness of a machine learning-based approach (recommender system) for computer-tailored health communication (CTHC).

Intervention Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Socio-environmental



Fayorsey 2019


HIV 26 22-30 > 16 340 100 Not Supplied/ Applicable

No We hypothesized that by combining interventions, we could target multiple barriers to engagement along the PMTCT cascade, social (peer mentoring, individualized health education at home and during clinic visits), behavioral (phone calls and SMS), and structural (enhanced referrals and patient escort) challenges threatening a woman's ability to remain in long-term PMTCT services.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental

Ferrao 2017 With chronic illness

Malaria (prevalence data - no participants recruited)

Not Applicable

Not Applicable

Not Applicable

490,561 Not Supplied/ Applicable


No Public precision health strategies can support decisions to reduce malaria by optimising resource use [8]. For example, decisions can focus spraying efforts to reduce vector numbers, where to build a water body, and when to drain it.

Risk assessment Socio-environmental

Ferrer 2017 No mention of health condition

Not Applicable 27.94 6.85 Not Supplied

1919 67.17 24.80 Yes Thus, a health-specific regulatory focus scale matched to the rationale for tailoring health messaging has the potential to further improve the precision with which framed health messages change behavior.


Fucito 2015 No mention of health condition


26 38.46 57.69 No Most participants reported that they did not relate to general health promotion campaigns (i.e., television commercials, health posters) focused on other people suffering from the negative effects of smoking but indicated that personalized health information would be motivating.

Intervention Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Gamp 2016 No mention of health condition

Not Supplied 30.7 10.5 Not Supplied


No Accordingly, when communicating personalised health risk information, physicians may inquire after pre-feedback risk expectancies in order to facilitate the processing of risk status information.


Gany 2012 No mention of health condition

Prediabetes, diabetes, prehypertensive range, high blood pressure, hypertensive range

Not Supplied

Not Supplied

>= 18 289 28.37 100 Yes The NYU School of Medicine Center for Immigrant Health (CIH) held four culturally and linguistically tailored health camps between October 2009 and November 2010 to educate participants about and screen for CVD risk factors, including diabetes, hypertension, and hypercholesterolemia.

Risk assessment Sociodemographic/ economic, Physiologic/ biochemical/ clinical



Gatwood 2020


Diabetes 60.8 Not Supplied

45 - 70 Not Supplied


100 Yes Consequently, tailored health communication is thought to improve the odds of capturing users' attention through individualization, increasing the likelihood that the message will be more thoughtfully considered and, ultimately, have a greater impact on health behavior.


Ghahari 2018 With chronic illness

Chronic health failure

67.4 Not Supplied

41 - 85 24 50 0 No Previous research found that providing properly tailored health data should be considered as a mean to activate individuals (Ball et al., 2007, Klasnja and Pratt, 2012, Pagliari et al., 2007).


Gholizadeh 2011


Not Supplied 44 11.63 21 - 63 66 100 100 Yes In this article, we provide insight into the women's experiences and perceptions of CVD and discuss implications for development and delivery of tailored health interventions to target the needs of this vulnerable group.


Gilmore 2017 At-risk/pre-clinical disease stage At-risk/pre-clinical disease stage

Overweight or obese

26 5.4 Not Supplied

40 100 67.5 Yes Thus, the objective of this study, E-Moms: A personalized mHealth intervention for health and weight loss in postpartum women, is to capitalize on the ease of increased contact and information delivery through SmartPhones to promote weight loss and improve diet quality in overweight and obese postpartum women enrolled in the supplemental nutrition Women, Infants, and Children’s program.

Intervention Anthropometric, Behavioural/ lifestyle/ physical activity

Ginsburg 2015


Breast cancer 60.71 13.65 <50 to >70

41296 t114.82 5.67 No Chinese-Canadian communities were among the first of Canada's ethnocultural groups to be offered tailored health promotion information on breast cancer16,20,39,40, but whether those initiatives are improving cancer outcomes remains unclear. More detailed data about ethnicity and immigration status would help to inform health policy, to target and tailor ethnoculturally appropriate health promotion initiatives, and to track the resulting clinical effects. Examining the association between ethnicity and stage at diagnosis is an important step in understanding cancer outcomes.

Risk assessment Sociodemographic/ economic, Physiologic/ biochemical/ clinical

Gonzales 2013


Ovarian cancer 65 Not Supplied


No In these interviews, we performed contextual inquiries to identify the key concerns oncologists have during their initial meetings with patients, as well as to brainstorm ideas for making it easier for oncologists to relay personalized health information.




Goodman 2017



Not Supplied

18 - 55 153 86.27 73.20 Yes Indeed, the literature supports culturally tailored health messages having greater influence in both print and online.


Gordon 2014 At-risk/pre-clinical disease stage

Colorectal cancer

69 Not Supplied

50 - 74 102 50 100 Yes Having such a tool would facilitate assessments in these areas of study while simultaneously enhancing cross-study comparisons. In addition, segmentation would allow for more uniquely targeted and tailored health messages.

Risk assessment Sociodemographic/ economic, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity

Gray 2014 With chronic illness

Diabetes Not Supplied

Not Supplied

45 - 80 13 38.46 Not Supplied/ Applicable

Yes Personalized health information content is provided based on people's specific needs, goals, and health conditions as these change over time.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity

Guinazu 2020 No mention of health condition


Not Supplied



No Precision health emphasizes in prevention and using shared-decision making with patients, policy makers and health workers offers an important opportunity to improve it in SUDs (substance-use disorders).

Data analytics Sociodemographic/ economic, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity

Guo 2018 Explicit "recruitment" of healthy populations, With chronic illness

Diabetes, gout Not Supplied

Not Supplied

Not Supplied



No The mIoTs is believed to fulfill the dramatically massive need for personalized healthcare management, which requires the pervasive digital medical devices linked and accessed to the Internet to interact all the parameters related to the personalized health, such as medical images, biochemical and biophysical parameters.



Han 2019 With chronic illness

Type 2 diabetes, Cirrhosis, NSCLC (non-small-cell lung cancer), RCC (renal cell carcinoma)

70 Not Supplied

Not Supplied

401 23.19 45.14 No A working knowledge of the micro-biome (our second genome27) is vital as we move forward in this age of precision health and precision medicine,28 especially in the area of cancer research, which aims at effective treatments for various kinds of cancer based on the knowledge of genetics, biology of the disease and host-microbiome interactions.29


Handley 2016 At-risk/pre-clinical disease stage

Prior Gestational Diabetes Mellitus

31.5 Not Supplied

Not Supplied

22 100 100 Yes ATSM programs represent a middle ground between live counseling and internet-based apps for tailored health communication and can access hard to reach populations not engaged in visit-based programs.

Intervention Physiologic/ biochemical/ clinical

Hardie 2011 No mention of health condition

Not Applicable 45 16 18 - 91 800 64 Not Supplied/ Applicable

No Recent research suggests that many Australians would be willing to adopt a genetically based personalised nutrition

Risk assessment Sociodemographic/ economic, Physiologic/ biochemical/



plan to maintain health and prevent illness (Pin, Critchley, & Hardie, 2008).

clinical, Perspective/ opinion/ usage

Haslam 2019 No mention of health condition


1120 13.04 13.04 No The Walking Works Wonders intervention involves tailoring health information according to employee's readiness to change.


Haze 2013 With chronic illness

Asthma Not Supplied

Not Supplied


0 No Therefore, a systems and procedure analyst mapped the RN care coordinators' workflow and determined four core areas the application would need to address to add value: Health assessment Personalized health plan Disease-specific education Communication for follow-up evaluation


Hernandez 2019


Smoking-related health problems

24.82 2.73 19 - 31 9428 Not Supplied/ Applicable

25.99 Yes Education affords a range of direct and indirect benefits that promote longer and healthier lives (Cutler and Lleras-Muney 2010; Hummer and Hernandez 2013; Mirowsky and Ross 2003; Warren et al. 2004) and stratify health lifestyles (Pampel et al. 2010).


Hollands 2013


Not Supplied 27.2 Not Supplied


No Such personalization of health riskinformation is applied within interventions in both clinical care and preventive medicine. Examples include the use of medical imaging scans to motivate behaviour change (Bovet,Perret, Cornuz, Quilindo & Paccaud, 2002; Hollands, Hankins & Marteau, 2010),behavioural interventions that tailor health information for recipients (Kroeze, Werkman& Brug, 2006; Neville, Oâ€™Hara & Milat, 2009) and the feedback of clinical biomarker results, such as lung function spirometry (Bize, Burnand, Mueller, Rî€ege Walther &Cornuz, 2009), and genetic tests for disease risk estimation (Hollands et al., 2012;Marteau et al., 2010).


Hong 2018 Explicit "recruitment" of healthy populations


Not Supplied



No Mobile electronics with their flexible design[1-4] and wireless data communication capabilities[5-7] extend their applicability in wearable bioelectronics[8-11] and personalized healthcare.[12-14]





Hors-Fraile 2018



Not Supplied

Not Supplied



No One of the ways in which technology is used to do so is by designing tailored health messages targeted at patients. Some such platforms use expert systems [8] that use the rules of human expert reasoning and infer results based on people's answers to questions about behavior knowledge and motivational aspects like attitude and self-efficacy. Yet another type of system is a recommender system, which aims at sending messages tailored to users' preferences [9,10,11]. These platforms employ algorithms to predict which message is most similar to its users' previously preferred messages.

Intervention Sociodemographic/ economic, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity

Huang 2020 No mention of health condition


Not Supplied

Not Supplied



No By analyzing and modeling individual logging behaviors, predicting the future heart rate of a user can be helpful for personalized health management through giving suggestions on customized exercise plan

Data analytics Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Huang 2019 With chronic illness

Breast cancer 57 Not Supplied


No The application of survival prognosis that incorporates Cox proportional hazards regression with a single transcriptomic dataset (Ching et al., 2018; Katzman et al., 2018; Shao et al., 2018) and with multi-omics data (Chaudhary et al., 2018; Poirion et al., 2018; Ramazzotti et al., 2018; Sun et al., 2018; Zhang et al., 2018a) is of major interest in precision health.

Data analytics Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Genetic/ genomic

Huh 2018 No mention of health condition


Not Supplied

20 - 49 1000000 45.7679 100 No The purpose of this study is to visualize big data using text mining and word clouds and to prepare measures, if any, of personalized health activities from more various perspectives

Risk assessment Sociodemographic/ economic, Anthropometric

Hwang 2010 At-risk/pre-clinical disease stage

Stroke Not Supplied

Not Supplied


No This function is connected to a recommendation service that generates the personalized healthcare course materials for their urgent needs.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Genetic/ genomic, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

Jackson 2014 No mention of health condition


467 59.10 10.92 Yes Successful programmes are those which are designed to meet the needs of employees (Price Waterhouse Coopers, 2008) which requires understanding employees' health behaviours to inform

Data analytics Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical



the development of appropriate, tailored, health promotion interventions.

activity, Psychological/ psychiatric

Jacobs 2018 With chronic illness

Breast Cancer 66 Not Supplied


Yes MyPath indexes these materials and provides patients with personalized information recommendations based on their diagnosis and treatments, and uses a comprehensive survey to elicit patient information needs and update content accordingly.

Intervention Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage


HIV 47.7 9.72 29 - 63 25 32 100 Yes We present how our findings guided the adaptation of a theory-based, culturally tailored HL (health literacy) intervention to improve medication adherence in HIV + SDH (to be tested in a future study).

Intervention Perspective/ opinion/ usage, Socio-environmental


Diabetes, hypertension, heart disease, hyperlipidemia, arthritis, COPD, anemia, hypothyroidism, cancer, gout, renal disease, and GERD

60.1 7.35 51 - 77 21 61.90 42.86 Yes We report on a sample of midlife and older persons with multimorbid chronic conditions who participated in a study designed to gather data on factors associated with medication adherence for the purpose of guiding the development of socially and culturally relevant, tailored mHealth interventions for midlife and older patients with multimorbid chronic conditions.

Intervention Sociodemographic/ economic, Perspective/ opinion/ usage, Psychological/ psychiatric

Jang 2018 No mention of health condition


6262 53.90 24.70 Yes Therefore, merely providing general instructions on a healthy diet might not ensure the success of health campaigns for low-SES populations. Instead, success might be ensured by providing tailored messages based on careful consideration of the population’s beliefs or life experiences.

Risk assessment Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Kampusch 2016

With acute illness, With chronic illness

Chronic lower extremity ulcers, chronic pain, neurological disorders, acute pain, peripheral arterial occlusive disease, and other diseases



No Focusing on personalized healthcare, it is essential to consider not only technological and clinical aspects during the early design phase, but also experiences and demands of users, i.e. patients and operators.


Kang 2019 No mention of health condition

Dyslipidemia 50.1 7.7 Not Supplied

18,025 11.65 0 No We believe that the identification of genes interacting with potentially modifiable risk factors will facilitate knowledge-based approaches to personalize health guidelines according to an individual's genetic profile.

Data analytics Sociodemographic/ economic, Anthropometric, Genetic/ genomic



Karatekin 2018


Not Applicable 19 3.1 18 - 49 321 76.01 28.97 No Fortunately, past research in regulatory focus provides us with several directions relating to how prevention focused individuals can be motivated to engage in health-related behaviors, through tailoring health messages to with their regulatory focus. For instance, individuals with high levels of ACEs might be more motivated by health messages that highlight the gravity of negative outcomes related with the health condition (e.g., insomnia, low energy, inability to do tasks) and present the treatment as a way to avoid them, instead of focusing on the benefits attained through the treatment and how it may help meet the hopes and aspirations of the individual (e.g., have more energy, feel great, become more productive).

Risk assessment Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Karkar 2016 With chronic illness

Irritable bowel syndrome

Not Supplied

Not Supplied


No Understanding individual variation and treating individual needs is important in medicine and clinical science, an approach also known as personalized medicine. Although this term historically emphasized genetics and pharmacology, it is now expanding to include other areas of health and disease,2 recapturing the importance of personalized health..... Single case designs (SCDs), sometimes referred to as n-of-1 trials, can potentially advance personalized health.3In this type of design, an individual serves as their own control, highlighting an individual’s response to an intervention rather than a group’s.


Perspective/ opinion/ usage, Diet/ nutritional

Kasthurirathne 2020


Not Applicable 44.1 16.6 18 - 107

72484 65.10 74.80 Yes The combination of precision health [1] and population health initiatives in the United States have raised awareness about how clinical, behavioral, social risk, and social determinants of health factors influence an individual's use of medical services and their overall health and well-being [2].

Data analytics Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Diet/ nutritional, Socio-environmental,

Katariya 2018 No mention of health condition


Not Supplied

Not Supplied

Not Supplied



No The system is used to re-rank health related recommendations obtained from third party health service providers, using the calendar-classified events to decide how much a given recommendation is relevant for the user. Thus, it can generate personalized health related recommendations.

Data analytics Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity



Kemp 2019 With chronic illness

Respiratory arrest, cardiac arrest, falls, pneumonia, high blood pressure, dementia, heart disease, depression, arthritis, osteoporosis, diabetes, chronic obstructive pulmonary disease, cancer, stroke

Not Supplied

Not Supplied

Not Supplied

28 60.71 35.71 No Lack of uniformity in health care delivery within and across communities, paired with convoy member and resident change, meant fluctuating health care arrangements, experiences, and outcomes captured by our core category, a process we label individualizing health care.




31.7 10 18 - 50 17 52.94 Not Supplied/ Applicable

No The control intervention encompassed individualised health education sessions covering topics such as exercise, diet, weight loss, and appropriate stretching.

Intervention Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity



Not Applicable

Not Applicable

Not Applicable



No In order to control for the psychosocial contact inherent with the physiotherapy treatment, the control treatment will encompass individualised health education sessions covering topics such as exercise, diet, weight loss and appropriate stretching, in a similar fashion to previously published clinical trials looking at physiotherapy management in older people with advanced hip OA.

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Kerrigan 2020


HIV 40 Not Supplied

18 - 66 410 100 100 Yes Related to this dynamic, one DR participant worried that some FSW receiving LA ART might stop using condoms consistently, if they believed that they were cured of HIV, further highlighting the importance of clear communication and tailored health education and messaging related to LA ART.

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Psychological/ psychiatric

Kessels 2011 No mention of health condition


No Indeed, systematic literature reviews suggest that tailoring is associated with stronger behavior change effects than generic health education, especially in nutrition education interventions (Brug, Oenema, & Campbell, 2003; Kroeze, Werkman, & Brug, 2006; Noar, Benac, & Harris, 2007), whereas a recent randomized controlled study confirmed that individually tailored nutrition education messages receive more attention from the reader than non-

Intervention Perspective/ opinion/ usage, Diet/ nutritional



tailored health communications (Ruiter, Kessels, Jansma, & Brug, 2006).

Khalilia 2011 With acute illness, With chronic illness

Hospital inpatient admissions

Not Supplied

Not Supplied



No Disease risk prediction along with tailored health communication can lead to an effective channel for delivering disease specific information for people who will be likely to need it.

Data analytics Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical,

Kim 2017 No mention of health condition

Not Applicable 22 2.45 19 - 29 100 62 100 No Given such documented superiority of customization over personalization, users who receive customized health information via their wearable device are more likely to adopt a positive evaluation of the information and a higher tendency toward self-preservation compared with those who receive personalized health information.



Kim 2015 With chronic illness

Type 2 diabetes 65.7 5 60 - 85 70 50 Not Supplied/ Applicable

No Real-time individualized feedback to data transferred from monitoring devices is essential in current u-healthcare systems.

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Kitagawa 2015


Not Supplied 26.29 0.58 18 - 80 821 51 Not Supplied/ Applicable

No However, those receiving non-personalized health information were not only more likely to engage in risky behavior compared to the pure control and other treatment groups, they also sought out additional sexual partners.


Kizakevich 2018


PTSD Not Supplied

Not Supplied

18 - 66 108 57.41 54.63 No To better support research in this domain, we first created the Personal Health Intervention Toolkit (PHIT), a mobile application (app) framework for personalized health intervention studies.

Intervention Sociodemographic/ economic, T23, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Kulyk 2015 No mention of health condition


Yes They could especially benefit from personalized health technologies, designed for their special needs.


Lan 2012 No mention of health condition


Not Supplied

Not Supplied



No The novel idea behind the proposed mechanism is to discover personalized health trend of a person from the historical health records and the personal life-style, such that effective prediction on potential diseases can be achieve based on the discovered health trend.

Risk assessment Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Lee 2012 No mention of health condition

Not Applicable 53.36 14.3 >= 35 83 100 Not Supplied/ Applicable

No HIMS-everyday (Health Improvement and Management System) manages the subjects' body weight, BMI, body fat, blood pressure, blood sugar, and daily habits on the basis of their personalized health information and induces the

Intervention Anthropometric, Physiologic/ biochemical/ clinical



subjects to take action for their health control by method of stimulation.

Lee 2014 At-risk/pre-clinical disease stage


74.9 7.5 61 - 89 11 27.27 45.45 No Advances in the area of mobile health (mHealth) technology and improvements in information technology have resulted in the design and development of new patient-centric models for the provision of personalized health care services [1].


Lee 2014 With chronic illness

Hypertension, hyperlipidemia, stroke, angina pectoris, myocardial infarction, diabetes, thyroid disease, kidney failure, osteoarthritis, rheumatoid arthritis, osteoporosis, tuberculosis, asthma, gastric cancer, hepatoma, colorectal cancer, breast cancer, cervical cancer, lung cancer, other cancers, hepatitis B, hepatitis C, and liver cirrhosis.

70.64 4.69 >= 65 716 47.07 Not Supplied/ Applicable

Yes This study provides vital insights that can be incorporated into the design of personalized health management strategies and the development of interventions program, specifically for HRQoL improvement for the elderly with chronic diseases.

Data analytics Not Supplied

Leinonen 2017




No In short, it included (1) automated tailored health information, exercise, and physical activity instructions based on the stage of exercise behavior change; (2) regular automated change check concerning the stage of exercise behavior change; (3) feedback on physical activity and sitting time; (4) Clans of Oulu conquering game based on a map and global positioning system (GPS; see below); (5) social networking; and (6) interface to communal youth services and a Web-based helpdesk for technical issues.

Intervention Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric (stage of change)

Liang 2011 At-risk/pre-clinical disease stage

Obesity 39.7 Not Supplied

Not Supplied



No Health communication is an important factor in disease prevention and health promotion. Research on health communication has shown that the most effective health communication is tailored health communication (THC). That is, message framing should be




congruent with individual message receivers' needs and characteristics (e.g. health locus of control), skills (e.g. reading skill), abilities (e.g. information literacy), and motivations (Salovey and Williams-Piehota, 2004; Rimer and Kreuter, 2006; Rothman et al., 2006; Hibbard et al., 2007; Updegraff et al., 2007)

Lim 2011 With chronic illness

Type 2 Diabetes 67.2 4.1 > 60 154 55.84 Not Supplied/ Applicable

No The u-healthcare system can potentially provide disease prevention, early diagnosis, and early treatment, as well as continuous followup that are available whenever and wherever they are needed and requested. Such personalized health care services are import to diabetic patients whose disease management is depends primarily on time and frequency.

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Lim 2018 Explicit "recruitment" of healthy populations

Not Applicable 47.49 11.44 21 - 69 233 58.80 100 No How well do wearable metrics (both step- and HR-based) correlate with CVMD risk markers such that they are useful in the areas of clinical and/or translational research and personalized health monitoring?


Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Liu 2019 With chronic illness

Angina pectoris 53.47 6.29 Not Supplied


No The authors set up an individualized health management team to provide professional guidance to the angina patients through training the team members' nursing theory and skills.

Intervention Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Liu 2020 With chronic illness

Autism Not Supplied

Not Supplied

Not Supplied



No The National Academy of Medicine [2] urges the research community to target high-need patients from smaller homogeneous subgroups for precision health with better outcomes.

Data analytics Sociodemographic/ economic, Genetic/ genomic, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Liu 2018 At-risk/pre-clinical disease stage

Overweight, obese

48 10.7 > 18 297 64.98 31.65 No The health partner and the participant then collaborated to create a personalized health plan that might include changes in diet or exercise, modification of risk-related behaviors (e.g., tobacco use, alcohol use), and stress reduction strategies such as yoga.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric



Lohmann 2013


Cancer Not Supplied

Not Supplied

Not Supplied



No Personalized health care (PHC) uses genetic information to understand requirements for health maintenance, disease prevention, and therapy. The aim of PHC is to select the right medicine at the right dose for the right patient at the right time [1-3].

Risk assessment Genetic/ genomic

Lu 2020 No mention of health condition


Not Supplied

Not Supplied

ns Not Supplied/ Applicable


No Our findings suggest that the existence of SCs (symptom clusters) which has robust relationships with related components of symptoms across different disease conditions acts a critical role in the directions in symptom science and precision health.

Data analytics Physiologic/ biochemical/ clinical

Lumpkins 2020

At-risk/pre-clinical disease stage, No mention of health condition

With a family member who has cancer

Not Supplied

Not Supplied

18 - 86 34 79.41 100 No Tailored health information that incorporates personal relevance and personal risk may increase an individual's health literacy and promote empowerment in decision making by representing relatable attitudes toward testing, beliefs about testing, and perceptions of cancer risk and control.

Risk assessment Genetic/ genomic, Perspective/ opinion/ usage

Luo 2020 With chronic illness

Hypertension Not Supplied

Not Supplied

Not Supplied



No In the long term, this will help patients with hypertension reduce information asymmetry with physicians by personalized health education and improve their compliance.


Mabuto 2017 With chronic illness

HIV median 34

Not Supplied


No Using data collected from a randomized entry-into-care study (Thol-impilo study), we analyzed the content of longitudinal counseling sessions to describe how structured IPC (interpersonal health communication) can provide precision health communication to encourage care seeking.

Intervention Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Socio-environmental

Magadzire 2017



Not Supplied



No The MOV strategy as described in the Methodology for the assessment of missed opportunities for vaccination will aim to demonstrate the magnitude and identify causes of these missed opportunities, followed by tailored health system interventions with the objective to reduce them, leading to an increase in vaccination coverage and timeliness of routine vaccinations.


Sociodemographic/ economic

Marthick 2019


Cancer 54 Not Supplied


No Personalized health coaching elements were designed to deliver a motivational interviewing style intervention through a remote delivery platform [15].


Martinsson 2018

With chronic illness With chronic illness

Type 1 diabetes Not Supplied

Not Supplied

Not Supplied

Not Supplied



No Nevertheless, our results suggest that a substantially reduced human effort-avoiding labor-intensive prior work by experts hand-crafting features based on extensive domain knowledge in designing and training machine learning




methods for precision health management can be feasible.

McHugh 2012


Obesity, overweight

41 9.3 22-63 238 34.87 Not Supplied/ Applicable

No Tailored communication is a promising approach to facilitating health behavior change given its ability to provide individualized information to large numbers of people

Intervention Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional, Socio-environmental

McPhee 2020 With chronic illness

Cerebral palsy 33.7 13.1 Not Supplied


No Future research should include individualized health reports that explain the relationship between health-risk factors and inactivity-related disease and the benefits of PA (physical activity) to adults with CP (cerebral palsy), while providing a longer, tailored intervention with information on how to overcome barriers to PA participation.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Socio-environmental

McReynolds 2019


Prostate cancer 56 Not applicable

Not Applicable


No In this era of precision health care, where new advances are being translated into clinical practice every day, it is vital that oncology nurses have a basic understanding of genomics.


Meng 2020 Explicit "recruitment" of healthy populations, With chronic illness , No mention of health condition

Obstructive sleep apnea-hypopnea syndrome, hypertension

65.66 Not Supplied


No Empowering the utility of the Internet of Things-enabled technology in personalized healthcare is still significantly challenged by the shortage of cost-effective and wearing comfortable biomedical devices to continuously provide real-time, patient-generated health data.



Mohan 2018 At-risk/pre-clinical disease stage, With chronic illness

At risk of Type 2 Diabetes / hypertension or with Type 2 Diabetes / hypertension

Not Applicable

Not Applicable

>=30 12243 54.15 Not Supplied/ Applicable

Yes The intervention components include tailored health promotion using social marketing approaches for increasing public awareness and promoting population risk factor modification and reduction;

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional, Socio-environmental



Moore 2019 With chronic illness

HIV, prehypertension

52 11.48 24 - 76 52 44.23 98.08 No Expanding on this definition, the goal of precision health is to integrate data about lifestyle and preferences, health status and behaviors, genomics, other physiological measures of health, and environment to design and deliver targeted, personalized interventions to assist individuals achieve and maintain optimal health and wellbeing (Khoury, Iademarco, & Riley, 2016).



Mozafarinia 2020


HIV Not Supplied

Not Supplied

Not Supplied


No The specific aims of this work were (1) to develop a personalized health outcome profile as a feedback tool to improve self management in people living with chronic conditions such as HIV and (2) to evaluate the interpretability and usefulness of the feedback tool for setting specific goals.


Nag 2018 No mention of health condition


Not Supplied


No Broadly, the motivation for this work in the Brave New Ideas track is to open the frontier into personalized health state estimation from multi-modal data.

Data analytics Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Socio-environmental

Nakamura 2018


Smokers 53.1 Not Supplied

40 - 74 47727 9.27 100 No Active support offers more intensive personalized health guidance comprised of face-to-face counseling for lifestyle modification, followed by repeated counseling for at least 3 months.

Intervention Sociodemographic/ economic, Anthropometric, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Nedungadi 2018



Not Supplied


Yes The platform consists of a combination of multiple low-cost invasive and non-invasive sensors, an interface unit and a personalized health monitoring and awareness application (Fig. 1).

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical

New 2020 At-risk/pre-clinical disease stage

Hypertension Not Supplied

Not Supplied

Not Applicable

Not Supplied



No When possible, as in these examples, domain knowledge should be used to infer what subpopulations are useful for a given precision health problem. In cases where existing knowledge is not sufficiently complete to do this, ma-chine learning methods can discover informative subpopulations that lie latent in large heterogenous datasets.

Data analytics Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical

Newman-Casey 2018


Glaucoma Not Applicable

Not Applicable


26.32 No In order to test the preliminary impact of the personalized eHealth intervention among non-adherent glaucoma patients, we will electronically monitor medication adherence longitudinally over 2 years.

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Socio-environmental



Nishita 2011 With chronic illness

Diabetes 48.5 9.7 20 - 62 190 62.63 82.63 No Understanding the associations between individual characteristics and self-perceptions can enable health care professionals to tailor health prevention interventions and programs to the needs of specific subpopulations.

Risk assessment Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric,

Noar 2011 At-risk/pre-clinical disease stage

Sexually transmitted diseases

26.93 6.9 18 - 44 293 45.73 100 Yes The current study represents the first step in a line of research to develop an innovative, computer-based tailored health communication intervention for African-Americans who visit a sexually transmitted disease (STD) clinic

Risk assessment Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental

Noble 2015 No mention of health condition


Not Supplied

>= 18 87 59.77 71.26 Yes Tailored health risk feedback contains less redundant information than generic feedback, and is therefore more likely to be read and remembered by individuals

Intervention Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

Oh 2014 At-risk/pre-clinical disease stage

Osteopetrosis 66.2 8.2 51 - 83 41 100 100 Yes The participants in the intervention group monitored their health status (i.e., general health assessment, blood pressure, pulse rate, and body weight), and brief individualized health counseling was provided during each session.


Page 2014 No mention of health condition


Not Supplied

Not Supplied



No Personalized health care depends crucially on large volumes of data about both individuals and populations. It is easy to imagine a near future in which it is common to wear a number of bio-sensors that continuously monitor various aspects of our physiological state, including heart rate, blood pressure, eye movement, brain activity, and many others.


Pak 2018 With acute illness

Typhoid fever Not Applicable

Not Applicable

Not Supplied

Not Supplied



No The goal of the HPAfrica study is to assess the generic and actual age-stratified and sex-stratified health behaviour.


Sociodemographic/ economic, Socio-environmental

Patel 2015 No mention of health condition

Not Applicable 43.05 13.29 18 - 75 83 59.04 27.71 No Additionally, providers indicated that the flexibility of such a platform could be used to provide tailored health information content through the use of disease or medical condition specific modules




Paterno 2020 At-risk/pre-clinical disease stage

Pregnancy Not Supplied

Not Supplied


No Personalized health monitoring devices have been used in physical activity (Cadmus-Bertram et al., 2015) and diet interventions, but not sleep interventions during pregnancy.

Intervention Behavioural/ lifestyle/ physical activity, Sociodemographic/ economic,

Pathinarupothi 2019

Explicit "recruitment" of healthy populations, With acute illness

Atrial fibrillation, acute hypotensive episodes

54 Not Supplied

Not Supplied



Yes Rapid Active Summarization for Effective Prognosis (RASPRO): A software algorithm that converts voluminous multi-sensor patient data into clinically interpretable summaries in the form of severity symbols that we call as Personalized Health Motifs (PHMs).



Pethiyagoda 2016


Acute respiratory failure

Not Supplied

Not Supplied

Not Supplied



No These existing models for risk prediction in the pediatric ICU fail to address additional relevant outcomes such as length of stay and risks associated regarding medical procedures to be performed, which may be more beneficial features to be considered to help increase ICU performance by better-personalized healthcare.


Pleasant 2020 No mention of health condition


Not Supplied

Not Supplied

Not Supplied



Not Applicable

Tailoring health communication is a method to enhance the relevance of the information presented, and tailored interventions are more effective than non-tailored ones


Poorani 2018 No mention of health condition


Not Supplied

Not Supplied


No Vignesh Raguraman et al 20157, proposed a Genetic Algorithm (GA) based Personalized Healthcare System (GAPHS) that collects vital health parameters from wearable sensors and then classifies the data based on the mean and encodes each parameter to represent as a gene in a chromosome.

Data analytics Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Popescu 2011 With chronic illness

Hypertension, diabetes mellitus, and coronary atherosclerosis

Not Supplied

Not Supplied

Not Supplied

7,995,048



No Disease prediction is employed in different domains such as risk management, tailored health communication and public health.

Data analytics Sociodemographic/ economic, Physiologic/ biochemical/ clinical

Pozaic 2013 Explicit "recruitment" of healthy populations


No Wireless Body Area Network (WBAN) for continuous and personalized health monitoring of basic physiological parameters (ECG, breathing rate and body temperature) was developed at the Department of Electronic Systems and Information Processing at the Faculty of Electrical Engineering and Computing, University of Zagreb and we added the functionality of mobility measurement and assisted exercising.


Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity

Prichard 2015 No mention of health condition

Colorectal cancer, breast cancer, heart

20.01 2.87 17 - 29 116 Not Supplied/ Applicable

12.93 No One week later, each participant received an email containing links to a tailored health message and general

Intervention Physiologic/ biochemical/ clinical,



disease, and diabetes

health information or general health information alone, depending on their category (FHH: average risk, FHH: above-average risk or Control).

Behavioural/ lifestyle/ physical activity, Diet/ nutritional, Socio-environmental

Qin 2018 No mention of health condition


Not Supplied

Not Supplied

Not Supplied



No A sensitive and rapid 1-N detection method using cost-effective and field portable sensor testing box has potential applications in personalized health monitoring and environmental monitoring.


Qin 2019 With chronic illness

Coronary atherosclerotic cardiopathy



No Meanwhile, the team leader conducted one-to-one instructions for the members of the personalized health management group on the weak links in the formulation of the theoretical knowledge of coronary atherosclerotic cardiopathy, the personalized health management method, the knowledge of controlling sodium and water intake, and the dietetic monitoring logs, so as to ensure that the members of the personalized health management group were familiar with the educational contents of the coronary atherosclerotic cardiopathy related knowledge, personalized health management, emotional management, and exercise training.

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Psychological/ psychiatric

Raat 2013 No mention of health condition

Not Applicable Not Applicable

Not Applicable



No The Ehealth4Uth Healthy toddler intervention consists of an E-health module providing tailored health education regarding healthy child nutrition and activity behaviors, which is combined with face to face counseling by YHC nurses.

Intervention Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Rabbi 2015 No mention of health condition


Not Supplied

19 - >50


No The novel functionality is an intelligent engine that provides personalized suggestions by learning a user's physical activity and dietary behaviors.

Intervention Perspective/ opinion/ usage, Psychological/ psychiatric, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Rapisarda 2013


HIV 51



No To clarify this issue, a tailored health surveillance program was applied to 3,138 HCWs from four Medical Institutions. All HCWs were screened for anti-HCV antibodies and for HCV-related extrahepatic manifestations.

Risk assessment Physiologic/ biochemical/ clinical, Genetic/ genomic



Reid 2018 With chronic illness

Type 2 diabetes mellitus

Not Supplied

Not Supplied

Not Supplied



Yes Such individual or group activities need to focus on tailored health communication during which patients could actively participate.


Rezai 2019 No mention of health condition

Not Supplied 23.55 5.8 18 - 65 120 72.5 Not Supplied/ Applicable

No Although public health researchers have studied a wide variety of techniques for tailoring health messages, their findings have not been employed broadly in the design of persuasive systems.

Intervention Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity

Rikard 2012 No mention of health condition


Not Supplied

18 - 65 21 66.67 100 Yes Culturally tailored health information captures a group's norms, values, practices, ways of life, and meanings


Rosas 2020 No mention of health condition


Not Supplied

>= 18 100 69 100 Yes Precision health is a new paradigm for health promotion, disease prevention, and treatment that takes into account heterogeneity in genes, environment, lifestyle, and social factors across groups for optimal maintenance of health and wellness across the lifecourse.


Rosenberg 2016


Cancer 57 Not Supplied

21 - 98 1615 88.67 9.29 No In this report, we describe and assess the degree to which an RAV (risk-adapted visits) and SCP (survivorship care plan) promote individualized health care and self-management at the re-entry phase as cancer survivors transition from active treatment to follow-up care.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Rykov 2020 Explicit "recruitment" of healthy populations

Not Applicable 44.3 11.9 22 - 65 87 21.84 100 No As greater adoption of wearables can enhance personalized health monitoring, scale up population health screening, and facilitate early detection of some diseases, research should explore associations between metrics derived from consumer-grade wearables and clinical and biological health markers.


Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Samaan 2013 At-risk/pre-clinical disease stage

Myocardial infarction

53.8 11.4 30 - 82 367 52.04 100 No Several studies have shown that multimedia interventions to manage risk factors of common disorders and to modify health behaviors are effective [13-19]. Multimedia interventions include use of email messaging, text messaging, video- or computer-based education, and electronic personalized health records, which are attractive because they involve components of goal setting and feedback key

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Genetic/ genomic, Behavioural/ lifestyle/ physical activity, Diet/ nutritional



components of health behavior modification, are relatively cost efficient, and have the potential to be scalable to large numbers of individuals.

Sant'anna 2014

With acute illness

Total hip replacement

65 15 Not Supplied



No In the future, what will individualized health care look like from an institutional perspective?

Intervention Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Sastre 2019 No mention of health condition


Not Supplied

12 - 17 23 30.43 100 Yes Consequently, the objectives of this program with newly arrived immigrant and refugee youth were to (1) examine health and nutrition behaviors through digital photography and (2) utilize digital photography to address risks through development of tailored health promotion materials.


Savage 2018 At-risk/pre-clinical disease stage

Travel-related illness

Not Supplied

Not Supplied

18 - >65

32 68.75 100 No This article was conceived in collaboration with Peel Public Health to provide locally relevant information that could guide the development of tailored health promotion strategies.

Risk assessment Sociodemographic/ economic, Perspective/ opinion/ usage, Psychological/ psychiatric

Schussler-FiorenzaRose 2019


Type 2 diabetes 53.4 9.2 25 - 75 109 Not Supplied/ Applicable

44.95 Yes Precision health and medicine are entering a new era in which wearable sensors, omics technologies and computational methods have the potential to improve health and lead to mechanistic discoveries.

Data analytics Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Genetic/ genomic, Behavioural/ lifestyle/ physical activity

Sengupta 2019



Not Supplied

Not Supplied



No The growing demand for flexible, ultrasensitive wearable sensors for myoelectric prosthesis, soft robotics, and personalized health monitoring applications has been the main driving factor behind the rapid advancement in soft and flexible material processing technologies.


Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Sim 2017 With chronic illness

Cancer 61.77 76.19 <65 to >65


Yes Recently, with the increased use of the Internet and smartphones, numerous information and communication technology (ICT)-based self-management programs have been developed to assist cancer patients with personalized health care,7,8 and these programs are expected to substantially improve health outcomes.

Data analytics Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Psychological/ psychiatric



Simione 2020 With chronic illness

Obesity 8.04 2.98 2-Dec 629 52.15 64.86 No We randomized children into one of two intervention arms: [1] enhanced primary care (n=361); or [2] enhanced primary care plus contextually tailored, health coaching (n=360).

Intervention Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity

Smith 2020 With chronic illness

Dementia 77.9 8.5 42 - 98 1434 52.02 5.51 Yes The growing move towards personalised health and social care systems [1, 2] means that every effort needs to be made to generate patient-reported outcome data.

Risk assessment Psychological/ psychiatric

Stewart 2019 At-risk/pre-clinical disease stage

Chronic diseases

Not Supplied

18 - >60


No Personalised health care, that is, health care tailored to an individual's characteristics and needs, is undergoing rapid developments.

Risk assessment Sociodemographic/ economic, Genetic/ genomic, Perspective/ opinion/ usage

Stewart 2018 Explicit "recruitment" of healthy populations

Not Applicable Not Applicable

Not Applicable



No Product 1: personalised health check (PHC). The PHC consists of the Health Potential service (future health) and a general health check of the customer's current health.

Intervention Sociodemographic/ economic, Perspective/ opinion/ usage

Stienen 2015 With chronic illness

Non-Hodgkin's Lymphoma

56 11 30 - 70 12 41.67 Not Supplied/ Applicable

No This also points to personalized care, which can be defined as the delivery of care that is tailored to an individual patient.


Stolee 2012 At-risk/pre-clinical disease stage

Co-morbid chronic medical conditions

76.2 8.3 >55 90 58.89 Not Supplied/ Applicable

No The frail older patients cared for in GDH typically have multiple, complex, and highly individualized health problems for which comprehensive, interdisciplinary assessment and treatment approaches are generally recommended.


Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Sturm 2018 With chronic illness

Coronary artery disease, type 1 diabetes, type 2 diabetes, hemochromatosis, melanoma, age-related macular degeneration, prostate cancer, and lupus


128 49.22 10.94 Yes He continued integration of precision health into clinical practice will require re-evaluation of conventional approaches as more patients seek genomic counseling and testing.

Risk assessment Sociodemographic/ economic, Genetic/ genomic, Perspective/ opinion/ usage

Sullivan 2020 At-risk/pre-clinical disease stage

Mortality Not Supplied

Not Supplied



No Precision health initiatives, which aim to deliver personalized decision support recommendations, are becoming increasingly more important in promoting person centered care.

Risk assessment Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Psychological/ psychiatric



Sun 2019 With chronic illness




No In the present study, based on the full-course disease management model and the individual features of patients, we applied full-course individualized health education (FCIHE) in CHF patients, providing patients with scientific, professional, and tailored health guidance and helping them learn and adopt the concept of self-care behavior, in an attempt to provide new guidance for the development of self-care programs for CHF patients.

Intervention Physiologic/ biochemical/ clinical, Psychological/ psychiatric, Socio-environmental

Sztyler 2015 No mention of health condition




No In this context, personalized health solutions and lifestyle monitoring can help to ensure that people doing the right activity at the right time. However, the regular use of such methods is critical to achieve the desired result. Hence, barriers for the adoption must be low, and using both software and devices should be as comfortable as possible.


Sociodemographic/ economic, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity

Tabatabaei 2018



Not Supplied

Not Supplied



No Reinforcement learning is a natural choice for personalization for health and wellbeing as it focuses on selecting the best actions with a more long term reward in mind.

Data analytics Sociodemographic/ economic, Behavioural/ lifestyle/ physical activity

Takahashi 2014


Cancer Not Supplied

Not Supplied

Not Supplied

168 32.74 100 No Genomic information has been proposed to be utilized as the basis for personalized health care.

Data analytics Sociodemographic/ economic, Anthropometric, Genetic/ genomic, Behavioural/ lifestyle/ physical activity

Tampubolon 2018

With acute illness

Wound from circumcision

8.7 2.2 5-Dec 20 Not Supplied/ Applicable


No In the era of personalized health, the quest for biomarker as tools of examination, of diagnosis and of follow up deemed necessary.



Taualii 2014 No mention of health condition

Cancer Not Supplied

Not Supplied

18- >65

92 78.26 100 No Genomic science represents a new frontier for health research and will provide important tools for personalizing health care [1]. Biorepositories are facilities that collect and store specimens, "for example, blood, cord blood, placentas, and cancer tissue “for future research


Taylor 2018 No mention of health condition

Not Applicable 67 11 42 - 92 52 76.92 7.69 No Other research describes the uncertainty that informal caregivers of OA with chronic conditions often live with, and their need for general and tailored health information that is detailed, proactive, timely, and communicated at different times of illness.


Thiel 2011 No mention of health condition


Not Supplied

15 - 18 1138 37.17 100 No The studies' results will serve as the basis for tailored health promotion strategies to be developed in




cooperation with representatives of German elite sports' associations.

Thompson 2017


Human Papillomavirus

21.3 2.1 18 - 26 50 100 24 No Moreover, future interventions based on this research can tailor health information and messages specific to the unvaccinated subgroups of interest (i.e., women in monogamous relationships) and reinforce messages to assist women in assessing risk for acquiring HPV infection


Truong 2020 No mention of health condition


Not Supplied

Not Supplied


0 No This result suggests that polygenic prediction integrating family information will be a useful tool for precision health and preventive medicine.

Risk assessment Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Genetic/ genomic, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric

Tseng 2018 No mention of health condition


Not Supplied

Not Supplied



No Lin et al. [8] proposed VASP (Virtual Assistant System for Personal health management), a virtual assistant system for personal health management, which can analyze the report of regular comprehensive physical examination result to evaluate the health risk and provide personalized healthcare services for users in terms of diet and exercise guideline recommendations.

Data analytics Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity

Tucker 2016 No mention of health condition

Not Applicable 43 12.4 21-64 40 100 2.5 No The primary purpose of this study was to explore the feasibility, preliminary effects, and barriers and facilitators of integrating a 6-month worksite NEAT+ PA intervention, with personalized health coaching via text messaging, into the workflow of ambulatory clinic nursing staff (RNs and MAs).


Turner 2014 No mention of health condition


Not Supplied

Not Supplied



No Evidence based, personalized health care depends crucially on large volumes of data about both individuals and populations.


vandenBrekel-Dijkstra 2016




Yes It offers users an individually tailored health management plan, which may include advice to visit a health professional for further diagnostic testing or evaluation, to change health-related lifestyle behaviour(s), and/or to maintain present healthful behaviours.

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/



nutritional, Socio-environmental

vandenBroek 2017



Not Supplied

Not Supplied

Not Supplied



No Proteins are major drivers of many disease pathways, and remote or longitudinal sample collection would offer great opportunities in population-based or personalized health monitoring [1], [2].



vandenBroek 2017



Not Supplied


No The visual nature of the method enables intuitive display and tracking of individual health status. In personalized health, this can serve as both a personal feedback method and a way to determine and address areas of health in which changes are occurring, for targeted advice and interventions.


Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

vanDongen 2019


Not Applicable Not Applicable (protocol)

Not Applicable (protocol)

Not Applicable (protocol)



No Fourth, the activities generate outputs including increased community capacity and the implementation of tailored health-promotion activities, the ownership of which is held by the school community itself.

Intervention Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

vanLimpt 2011

At-risk/pre-clinical disease stage, With chronic illness

Cardiovascular disease or diabetes, or with only a high cardiovascular risk

62.2 Not Supplied

<= 75 1275 65.73 Not Supplied/ Applicable

No The health advisor should complete computerized risk profiles, should give tailored health education and advices and should confer with the GP to optimize treatment.

Intervention Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity

vanOs 2017 Explicit "recruitment" of healthy populations, At-risk/pre-clinical disease stage, With acute illness, With chronic illness

Psychotic disorder, depression, residual depression

Not Supplied

Not Supplied

Not Supplied



No In this article, we will discuss how the collection of intensive contextual mental state data, known as the experience sampling method (ESM) or ecological momentary assessment (EMA; Csikszentmihalyi, Larson,&Prescott, 1977), in the form of an mHealth smartphone application, has the potential to become a mainstream instrument to support self-monitoring, personalized health care and the development of self-insight and avenues for personal change and acceptance of disabilities in clinical practice.

Data analytics Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

Vaughn 2019 With chronic illness

Oncologic, hematologic, immunologic, or metabolic diseases

Not Supplied

Not Supplied

Jul-18 20 Not Supplied/ Applicable


No Although PBMT symptoms and symptom clusters may not be completely prevented or eliminated, data from mobile technologies can be leveraged to help patients, caregivers, and clinicians monitor symptoms and develop personalized health strategies.


Sociodemographic/ economic, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity,



Psychological/ psychiatric

Vela 2019 No mention of health condition


Not Supplied

Not Supplied



No In the end, the integration and suitability of these solutions for medical and personalized health monitoring applications may be unclear.


Anthropometric (height, weight, etc.)

Vilaro 2017 No mention of health condition


1292 1.32 49.15 No The measure may yield key information for tailoring health behavior change interventions and understanding how priorities may vary based on participant characteristics, which may be particularly important for students with nonhealth-related food choice priorities.

Risk assessment Diet/ nutritional

Vosbergen 2015






Other: While tailoring health communication materials to specific types of pathology, therapies, behaviors, or psychological characteristics of patients has been found to be beneficial individual differences in patients' preferences for message features are rarely considered.

Intervention Sociodemographic/ economic, Perspective/ opinion/ usage

Wahbi 2018 At-risk/pre-clinical disease stage

Dystrophy type 1



No A reliable prediction of long-term mortality in this progressive disease is of major importance to plan a personalized health surveillance program based on appropriate screenings, monitoring of manageable complications, and specific preventive measures to improve its prognosis.

Risk assessment Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Behavioural/ lifestyle/ physical activity

Wang 2016 No mention of health condition


Not Supplied



No With the increasing popularity of mobile devices and development of wireless communication network technologies, more and more studies integrate mobile devices and context-aware technology for developing healthcare service platforms to support personalized health management to enhance the effectiveness of preventive medicine.


Weijers 2018 Other 'Specific medical or complex issues'

3.9 Not Supplied

Not Supplied


No A transformation of the current conventional health care, with treatment after a diagnosis (find it and fix it) to a predictive and personalized health care (predict it and personalize it) is needed.

Risk assessment Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Genetic/ genomic, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Socio-environmental

Wheeler 2018 With chronic illness

Crouzon Syndrome

Not Supplied

Not Supplied

18 - 78 9 55.56 11.11 Yes Without effective coping strategies, remaining physical, psychological, and emotional scars may impede the overall





QOL of those with CS. There is a need to develop tailored health education resources and services for this population and for the health practitioners, providers, and family members who support them.

Williams 2019



Not Supplied

Not Supplied

16,894 Not Supplied/ Applicable


No We therefore hypothesized that protein scanning could deliver comprehensive individualized health assessments but with single-source convenience and greater usability in typical medical practice.


Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity, Diet/ nutritional

Xia 2010 At-risk/pre-clinical disease stage

Tuberculosis Not Supplied (protocol)

Not Supplied (protocol)

Not Supplied (protocol)

Not Supplied



No The aim of ADACS was to recognize incidences, prognoses, impacts, and risk factors of anti-tuberculosis drugs induced ADRs in CNTS, and provide individualized health care and TB control policy suggestions.

Risk assessment Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Genetic/ genomic

Xiao 2019 No mention of health condition


Not Supplied

Not Supplied



No As summarized in Section 2, various approaches were proposed to either learn physiological patterns from behavioral data or provide personalized health recommendation or both.

Data analytics Behavioural/ lifestyle/ physical activity

Yang 2013 At-risk/pre-clinical disease stage

Excess weight during pregnancy

32 Not Applicable - just one participant

32 1 100 Not Supplied/ Applicable

No Personalized health planning with integrative health coaching (PHP-IHC) is a strategic intervention that applies a holistic and individualized approach to optimizing physical, mental, and social health.

Intervention Sociodemographic/ economic, Anthropometric, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional, Socio-environmental

Youm 2017 No mention of health condition


Not Supplied

Not Supplied



No To examine the differences in the level of interest in health and the amount of exercise between a group of individuals that consistently utilized a personalized health management program using a Home healthcare PC and a group of individuals who did not, a 16-week long study was conducted on 143 male and female adults residing in the Gyeongnam region.

Intervention Sociodemographic/ economic, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity

Zang 2017 Explicit "recruitment" of healthy populations



No Aware of the seriousness and potential risk of this issue, people pay more attention to their health status and eagerly require more related information to realize personalized healthcare.


Sociodemographic/ economic, Physiologic/ biochemical/ clinical



Zhou 2010 Explicit "recruitment" of healthy populations, With acute illness, With chronic illness


2073 49.59 100 No The individualized health intervention (IHI) model has been used especially in behavior change, and has been proved successful

Intervention Sociodemographic/ economic, Anthropometric, Physiologic/ biochemical/ clinical, Perspective/ opinion/ usage, Behavioural/ lifestyle/ physical activity, Psychological/ psychiatric, Diet/ nutritional

Zhu 2017 With chronic illness


Not Supplied

Not Supplied

Not Supplied



No Therefore, risks assessment of readmission for discharging patients and analysis of its risk factors can provide personalized health management advice for both patients and followed-up doctors.

Risk assessment Sociodemographic/ economic, Anthropometric



Appendix 1. PRISMA-ScR checklist - BMJ Open

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Transcript of Appendix 1. PRISMA-ScR checklist - BMJ Open