Makalah Hidroksi Apatit Implan

7/25/2019 Makalah Hidroksi Apatit Implan

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MAKALAH ILMU BIOMATERIAL III

Hydroxyapatite Implant

Dosen Pembimbing:

Prof. Dr. drg. Widjijono, U.

Tim Pem!"!#!$ :

PDG GANJIL KELOMPOK VII

Adhitya Sofiyati Dewi 9609

Suci Atika 96!

Mae"u#ah $u%ia O 96&

A#d'a#i P(a)etia O 96&!

*he(e)ia Ve+a) K 96&9

Lu%uk Lutfia#a 96,,

-a#a Sa%)a.i%a 96/

Maya Sa(i ta"i 96/,

1e.ecca2 $u#u) 96/9Si3a(u.i#i2 1e#+a#atha# 964,

Siti Nu( 5a'a(2 -ohdi 964!

Syawa#i Ak"a%2 Ah"ad Ka"a% 9649

1

%AKULTA KEDOKTERA& 'I'I

U&I(ERITA 'AD)AH MADA*O'*AKARTA

+-


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KATA PE&'A&TAR

Pu'i )yuku( kehadi(at *uha# $a#+ Maha E)a2 ka(e#a .e(kat (ah"at da# hidayah7Nya

8e#u%i) da8at "e#ye%e)aika# "aka%ahHydroxyapatiteImplant:;

Pe#yu)u#a# "aka%ah i#i di"ak)udka# )e.a+ai )a%ah )atu )ya(at 8e#i%aia# da%a" "ata

ku%iah I%"u


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DA%TAR II

>>>>>>>>>>>>>>>>>>>>>>; /

I; Lata( >>>>>>>>>>>>>>>>>>>>>; /I;& 1u"u)a# Ma)a%ah >>>>>>>>>>>>>>>>>>>>> 4I;, *u'ua#>>>>>>>>>>>>>>>>>>>>>>>>>;;; 4

>>>>>>>>>>;; 6

II;,; SifatHydroxyapatite Implant>>>;;;;;;;;;;;>>>>>>>>>>>;; ?

II;/ I#dika)i da# Ko#t(ai#dika)iHydroxyapatite Implant>>>>>>>> 0

II;4 Keu#tu#+a# da# Ke(u+ia#Hydroxyapatite Implant>>>>>>>>>


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BAB I

PE&DAHULUA&

-.- L!/!r Be#!"!ng

Sei(i#+ de#+a# ke.utuha# .io"ate(ia% ya#+ "e#i#+kat2 ha% i#i "e"icu

.e(.a+ai u8aya u#tuk "e#ca(i a%te(#atif .io"ate(ia% ya#+ da8at "e#++a#tika#

)t(uktu( 'a(i#+a# ya#+ hi%a#+ ta#8a "e#i".u%ka# efek ya#+ #e+atif )e(ta te('a#+kau

o%eh "a)ya(akat; Pe#i#+kata# ke.utuha# "a)ya(akat da%a" 8e#++u#aa# .io"ate(ia%

da%a" .ida#+ kedokte(a# te(uta"a .a+ia# tu%a#+ da# +i+i di)e.a.ka# o%eh

"e#i#+kat#ya ka)u) 8atah tu%a#+ da# ke(u)aka# +i+i @Ku(#iawa#2 &00?; Sa%ah )atu

.aha# ya#+ )eda#+ dike".a#+ka# )e.a+ai .io"ate(ia% )i#te)i) ada%ah .ioke(a"ik;Ke%e.iha# .ioke(a"ik ada%ah "e"i%iki .ioko"8ati.i%ita) ya#+ .aik de#+a# )e%7)e%

tu.uh di.a#di#+ka# de#+a# .io"ate(ia% 8o%i"e( atau %o+a" @5e#ch2 99;


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-.1 T0j0!n

; Me#+etahui defi#i)i da(iHydroxyapatite Implant

&; Me#+etahui ko"8o)i)i ya#+ te(da8at da%a"Hydroxyapatite

,; Me#+etahui )ifat ya#+ te(da8at da%a"Hydroxyapatite

/; Me#+etahui i#dika)i da# ko#t(ai#dika)i 8e#++u#aa#Hydroxyapatite Implant

4; Me#+etahui keu#tu#+a# da# ke(u+ia# 8e#++u#aa#Hydroxyapatite Implant


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BAB II

PEMBAHAA&

+.- DefinisiHydroxyapatite Implant

I"8%a# ada%ah .aha# atau "ate(i )e8e(ti 'a(i#+a# atau .aha# ya#+ .e()ifat

a%o8%a)tik ya#+ di"a)ukka# ke da%a" tu.uh da# .e(tu'ua# u#tuk te(a8eutik2

dia+#o)tik2 8(o)tetik atau ek)8e(i"e#ta% )eca(a %e#+ka8 atau 8a()ia%; @A#u)a3ice2

&0,

5id(ok)ia8atit @5A de#+a# (u"u) "o%eku% Ba0@PO/6@O5&"e(u8aka#

ka%)iu" a8atit .ioke(a"ik ya#+ da8at dite"uka# da%a" +i+i da# tu%a#+

"a#u)ia @=it(iawa#2 &0/; 5id(ok)ia8atit "e(u8aka# .aha# o))eoko#duktifdi+u#aka# u#tuk "e"icu bone graftda# "e#u#'ukka# .ioko"8ati.i%ita) .aik de#+a#

'a(i#+a# %u#ak )e8e(ti ku%it2 otot da# +u)i2 )ehi#++a "e#'adi )e.uah "ate(ia% ya#+

idea% u#tuk o(to8edi da# i"8%a# +i+i @Acto#2 &0,;

Da%a" du#ia kedokte(a# "ode(# )e#di(i "ate(ia% hid(ok)ia8atit .a#yak

di+u#aka# )e.a+ai 8e#++a#ti tu%a#+ "a#u)ia ya#+ (u)ak ka(e#a )t(uktu(#ya ya#+

"e"a#+ )a#+at "i(i8 da# )e)uai de#+a# tu%a#+ "a#u)ia; O%eh ka(e#a

ke)e)uai#ya te()e.ut "aka tu%a#+ (etak2 8atah2 atau (u)ak ya#+ di(eko#)t(uk)ide#+a# hid(ok)ia8atit da8at de#+a# ce8at "e".a#+u# ikata# de#+a# tu%a#+ a)%i

da%a" tu.uh "a#u)ia @=it(iawa#2 &0/;

Hydroxyapatite Implantada%ah "ate(ia% .ioaktif )i#te)i) ka%)iu" fo)fat ya#+

di+u#aka# )e.a+ai .aha# i"8%a# au+"e#ta)i da# 'u+a )e.a+ai 8e%a8i) .aha# i"8%a#

"eta% "au8u# ce(a"ic2 .e()ifat #o#i"u#o+e#ik da# .ioko"8ati.e% de#+a# 'a(i#+a#

ho)t )e(ta "e"icu 8e(tu".uha# tu%a#+ .a(u de#+a# ca(a "e".e#tuk ikata# %a#+)u#+

a#ta(a .aha# i"8%a# da# 'a(i#+a# ke(a) ya#+ ke"udia# te('adi ka%)ifika)i @A#u)a3ice2

&0,;

+.+ Kom2osisiHydroxyapatite

St(uktu( k(i)ta% )e#yawa hid(ok)ia8atit da8at di.edaka# "e#'adi dua 'e#i)

yaitu "o#ok%i# da# hek)a+o#a%; "u"#ya k(i)ta% hid(ok)ia8atit ya#+ di.uat de#+a#

ca(a )i#te)i) "e"i%iki )t(uktu( k(i)ta% hek)a+o#a%; St(uktu( hid(ok)ia8atit hek)a+o#a%

"e"i%iki 'a(ak )i"et(i a#ta( +u+u) P6,F" de#+a# 8a(a"ete( ki)i a . 9;/,& 2 c

6;?? da# H &0o; St(uktu( k(i)ta% i#i te()u)u# ata) +u+u) PO/ tet(ahed(a% ya#+


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diikat o%eh io# io# Ba; Io# io# Ba .e(ada 8ada dua 8o)i)i .e(.eda yak#i 8o)i)i

ko%o" )e'a'a( @Ba da# 8o)i)i )e+iti+a )a"a )i)i @Ba& ya#+ .e(ada 8ada 8u)at )u".u

8uta(; Su)u#a# O5 "e".e#tuk ko%o" da# .e(ada 8ada )u".u 8uta(2 'u+a "e".e#tuk

)u)u#a# de"ikia# de#+a# O5 ya#+ te(dekat; St(uktu( k(i)ta% hek)a+o#a%

hid(ok)ia8atit ditu#'ukka# 8ada Ga".a( &;;

'!mb!r +.-.St(uktu( K(i)ta% 5ek)a+o#a% 5id(ok)ia8atit @Bo(#o2 dkk;2 &006

St(uktu( k(i)ta% "o#ok%i# hid(ok)ia8atit aka# te(.e#tuk a8a.i%a da%a" keadaa#

)toikio"et(ik; St(uktu( k(i)ta% "o#ok%i# "e(u8aka# )t(uktu( ya#+ 8a%i#+ te(atu( da#

)ta.i% )eca(a te("odi#a"ika wa%au8u# 'ika dite"8atka# da%a" )uhu (ua#+a#; St(uktu(

k(i)ta% "o#ok%i# hid(ok)ia8atit dite"uka# 8e(ta"a ka%i da(i 8(o)e) 8e#+u.aha# k(i)ta%tu#++a% k%o(a8atit "e#'adi k(i)ta% tu#++a% hid(ok)ia8atit de#+a# "e"a8a(ka##ya 8ada

ua8 ai( .e()uhu &00oB; St(uktu( k(i)ta% "o#ok%i# hid(ok)ia8atit "e"i%iki 'a(ak

)i"et(i a#ta( +u+u) P&F. da# 8a(a"ete( ki)i a 9;/& 2 . &a2 c 62?? da# H

&0o; St(uktu( k(i)ta% "o#ok%i# hid(ok)ia8atit ditu#'ukka# 8ada Ga".a( &;&;

'!mb!r +.+.St(uktu( K(i)ta% Mo#ok%i# 5id(ok)ia8atit @Bo(#o2 dkk;2 &006


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3'!mb!r +.1. Scanning Electron Micrograph8e("ukaa# 5A de#+a# 8e(.e)a(a#

0;000 @O#+ da# Bha#2 999;

T!be# +.-.Ko"8o)i)i Ki"ia 5A 8ada E"ai% Gi+i Ma#u)ia da# 5A da%a"

Stoikio"et(i @O#+ da# Bha#2 999;

+.1 if!/Hydroxyapatite

!.4 if!/ %isis

K(i)ta% a8atit "e"i%iki )ifat +eta) )e8e(ti ke(a"ik2 "e"i%iki wa(#a ya#+ )e)uai de#+a#

ti8e a8atitC .ia)a#ya hi'au2 a.u7a.u2 "e(ah2 cok%at2 .i(u2 3io%et atau tidak .e(wa(#a;

Mi#e(a%#ya )e#di(i da8at t(a#)8a(a# atau o8aue de#+a# +a(i) 8utih; Ke.a#yaka#

a8atit .e()ifat flouroscent 8ada )i#a( u%t(a3io%et2 )i#a( katoda atau )i#a(7 @O#+2

999; Mik(ok(i)ta% a8atit .e(uku(a# 907&,0 "i%i"ik(o#2 )t(uktu( 8o(u) i#i

"e"u#+ki#ka# 8e".u%uh da(ah da# 'a(i#+a# ikat "a)uk dia#ta(a 8o(u)#ya )ehi#++a

da8at "e(a#+)a#+ 8e".e#tuka# tu%a#+ @Setiadi da# Setiyohadi2 996;


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b.4 if!/ "imi!

5id(ok)ia8atit )ta.i% 8ada 85 di ata) /2& da# )ta.i% 8ada )uhu ,40 0 B; Sta.i%ita) )uhu

hid(ok)ia8atit "e#i#+kat )e)uai de#+a# teka#a# 8a()ia% @5a(to"o2 99&;

5.4 if!/ Me"!nis

Pe(.a#di#+a# da(i 8e#+a"ata# )ifat "eka#i) hid(ok)ia8atit te(ca#tu" da%a" ta.e%;

Ke(a"ikF'a(i#+a# ke(a) Compressive strength

@MPa

Tensile strength (MPa

*u%a#+ ko(tika% ,4760 6970De#ti# &94 42!E#a"e% &!0 !0

5id(ok)ia8atit ya#+ 8o(u)

@ti8i)

,07!0 /2?

5id(ok)ia8atit ya#+ #o# 8o(u)

@8adat

9! !?796

T!be# +.+.Ko"8(e)if da# Kekuata# *e#)i% da(i Ja(i#+a# Ke(a) da# 5id(ok)ia8atit

@Ducheye#e da# 5a)ti#+)2 &000;

5id(ok)ia8atit @5A "e"i%iki ko#duktifita) te("a% da# ko#duktifita) e%ekt(i) ya#+(e#dah )e(ta "e"i%iki )ifat e%a)tik ya#+ )a"a de#+a# tu%a#+ @Sak+uchi da# Powe()2

&0&;

ku(a# 8o(u)ita) da(i 8a(tike% hid(ok)ia8atit "e"e+a#+ 8e(a#a# 8e#ti#+ 8ada 8(o)e)

8e(tu".uha# 'a(i#+a# tu%a#+2 "e%a%ui %u.a#+ 8o(u)ita) i#i cai(a# da(i 'a(i#+a# ikat

"a)uk ke 8e("ukaa#; ku(a# 8a(tike% ku(a#+ da(i 0 "ik(o# aka# "e#+ha%a#+i

8e(tu".uha# )e%2 uku(a# 4740 "ik(o# da8at "e(a#+)a#+ 8e(tu".uha# fi.(o3a)ku%e(2

8ada uku(a# 40740 "ik(o# da8at "e#+ha)i%ka# 8e".e#tuka# o)teoid da# 8ada

uku(a# %e.ih da(i 40 "ik(o# "e"u#+ki#ka# u#tuk te('adi#ya "i#e(a%i)a)i tu%a#+

@P(iya".odo2 99!;

d.4 if!/ Bio#ogis

5id(ok)ia8atit "e"i%iki ke"a"8ua# .e(taha# te(hada8 ko(o)i da# "e"i%iki )ifat

.ioko"8ati.i%ita) ya#+ ti#++i @=athi et a%2 &00!;


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5id(ok)ia8atit "e"i%iki akti3ita) .io%o+i "ito+e#ik da# o)teot(o8ik; Mito+e#ik

didefi#i)ka# )e.a+ai )uatu ke"a"8ua# u#tuk "e#)ti"u%a)i )e% da(i 'a(i#+a#

8e#ya#++a2 )eda#+ka# o)teot(o8ik didefi#i)ika# )e.a+ai ke"a"8ua# u#tuk

"e#+e".a#+ka# diffe(e#)ia)i )e% ya#+ "a"8u u#tuk o)teo+e#e)i) @P(iya".odo2

99!;

5id(ok)ia8atit 'u+a "e"i%iki )ifat o)teoko#duktif2 .uka# o)teoi#duktif; A(ti#ya2

.aha# i#i da8at "e(a#+)a#+ 8e".e#tuka# tu%a#+ .i%a di%etakka# di dekat 'a(i#+a#

ya#+ "e#+a#du#+ tu%a#+ @P(iya".odo2 99!;

5id(ok)ia8atit "e"i%iki )ifat .ioaktif;


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b.4 Kon/r!indi"!si

I"8%a# 8ada tu%a#+ ko(tek) ya#+ ti8i) da# t(a.eku%a ya#+ de#)ita)#ya

(e#dah @tu%a#+ ti8e IV %e.ih (e#ta# +a+a% @Gu%)ahi2 &0; Ke.a#yaka# .aha# i"8%a# ko#t(ai#dika)i u#tuk 8e#++u#aa# 8ada dae(ah

ya#+ "e#da8at teka#a# ya#+ .e)a( @A#u)a3ice2 &0,;

+. Ke0n/0ng!n d!n Ker0gi!n Pengg0n!!nHydroxyapatite Implant

!.4 Ke0n/0ng!n

5id(ok)ia8atit "e"i%iki )ifat .ioko"8ati.i%ita) ya#+ ti#++i da#

"e"8u#yai )ifat .ioaktif @A#u)a3ice2 &0,; 5id(ok)ia8atit da8at diko".i#a)ika# de#+a# .aha# i"8%a# %ai# )e8e(ti

tita#iu" "e".e#tuk titanium!calcium ion mixing@A#u)a3ice2 &0,; I"8%a# hid(ok)ia8atit "e".e(ika# ti#+kat 'a#+ka hidu8 ya#+ %e.ih ti#++i

di.a#di#+ka# de#+a# 8e("ukaa# i"8%a# %ai##ya @Si"u#ek2 &004 Me"u#+ki#ka# u#tuk 8(o)e) o))eoi#te+(a)i ya#+ ce8at da# %e.ih .aik

@Si"u#ek2 &004

b.4 Ker0gi!n

5id(ok)ia8atit ada%ah "ate(ia% i"8%a# ya#+ tidak )ta.i% 8ada .e.e(a8a

ko#di)i2 )e8e(ti i#f%a"a)i da# i#fek)i @A#u)a3ice2 &0,; 5id(ok)ia8atit "udah te(di)o%u)i @A#u)a3ice2 &0,; Se.uah )tudi "e#u#'ukka# .ahwa ke+a+a%a# 8e%a8i)a# hid(ok)ia8atit

da8at "e#ye.a.ka# ko%o#i)a)i .akte(i koku) da# .ata#+ )ehi#++a

"e#ye.a.ka# hid(ok)ia8atit "e#'adi .io(eaktif @A#u)a3ice2 &0,; Keka)a(a# 8e("ukaa# i"8%a# hid(ok)ia8atit da8at .e(ko#t(i.u)i te(hada8

8e(tu".uha# 8%ak2 8e(i7i"8%a#titi)2 da# di)o%u)i @A#u)a3ice2 &0,; Sifat "eka#i) hid(ok)ia8atit tidak cuku8 kuat da# %e#tu( .i%a "e#e(i"a

daya te#)i%2 )ehi#++a di.ata)i 8e#++u#aa##ya 8ada dae(ah .e.a) teka#a#

@Pa#e2 &00/;


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BAB III

KEIMPULA&

; Hydroxyapatite Implant di+u#aka# )e.a+ai .aha# i"8%a# au+"e#ta)i "au8u# 8e%a8i)

8ada i"8%a# de#ta% ya#+ "e"icu 8e(tu".uha# tu%a#+ .a(u;&; 1u"u) ki"ia hid(ok)ia8atit ada%a%ah Ba0PO/6O5&2 St(uktu( k(i)ta% )e#yawa

hid(ok)ia8atit da8at di.edaka# "e#'adi dua 'e#i) yaitu "o#ok%i# da# hek)a+o#a%;

"u"#ya k(i)ta% hid(ok)ia8atit ya#+ di.uat de#+a# ca(a )i#te)i) "e"i%iki )t(uktu(

k(i)ta% hek)a+o#a% da# te()u)u# ata) io# ka%)iu"2 io# fo)fat da# io# hid(ok)i;,; SifatHydroxyapatite Implant"e%i8uti )ifat fi)ikC +eta)2 )ifat ki"iaC taha# 8ada 85 diata)

/2& da# )ta.i% 8ada )uhu ,400B2 )ifat "eka#i)C compressive strengthda# tensile strength


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ya#+ ha"8i( )a"a de#+a# hid(ok)ia8atit tu%a#+ ko(tika%2 )ifat .io%o+i)C a#tiko(o)i2

"ito+e#ik2 o)teot(o8ik2 o)teoko#duktif da# .ioaktif;/; I#dika)iHydroxyapatite Implant8ada dae(ah de#+a# ke8adata# tu%a#+ ya#+ %e.ih )e8e(ti

8ada tu%a#+ "a#di.u%a )eda#+ka# ko#t(ai#dika)i#ya 'ika di+u#aka# 8ada dae(ah ya#+

"e#da8at teka#a# .e)a(4; Keu#tu#+a# Hydroxyapatite Implant ada%ah "e"icu o))eoi#te+(a)i ya#+ %e.ih ce8at

)eda#+ka# ke(u+ia##ya ada%ah 5A "udah te(di)o%u)i atau te(de+(ada)i;

BAB I(

DA%TAR PUTAKA

A#u)a3ice2 K;J;2 She#2 B; 1aw%)2 5;1;2 &0,2Phillips" Sciece of #ental Materials Ed$ %&2

E%)e3ie( Sau#de()2 #ited State) of A"e(ica

A)hwo(th2J;L;2 1hati+a#2M;2 Sa"8ath21;2


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Ducheye#e P;2 da# 5a)ti#+)2 G;2 &0002 Meta% a#d Be(a"ic

Makalah Hidroksi Apatit Implan

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