Delapan tahun setelah fim pertama, Johnny English berlatih beladiri di Tibet untuk menebus dosanya karena misi yang gagal di Mozambik. Lima tahun kemudian, M17 meminta Johnny kembali bergabung bersama mereka.Johnny kembali Ke London ke markas M17 dan ditugaskan oleh Pegasus untuk menghentikan rencana pembunuhan Perdana mentri cina. Johnny juga bertemu sesama agen bernama Simon Ambrose dan pemilik M17 bernamapatch Quartermain. Dia juga ditugaskan dengan seorang agen junior bernama Colin TuckerDi Hongkong, Johnny bertemu dengan Mantan agen CIA bernama Tutis Fisher yang adalah salah satu anggota "Vortex" yang menggagalkan misinya di Mozambik dan salah satu diantara mereka adalah pembunuh Perdana mentri Cina, Titus memberikan sebuah kunci liga dan mengatakan bahwa jika salah satu kuncinya hilang, maka tamatlah Vortex. Namun Titus dibunuh oleh seorang penembak jitu bayaran yang ahli menyamar dan kunci tersebut jatuh ke tangan salah satu anggota Vortex, pengejaran berlangsung dengan seru dibantu dengan peralatan canggih pemberian M17, beruntung kunci tersebut berhasil didapatkan.Saat penerbangan kembali ke London, Johnny bersifat sangat tenang lalu menjelang pendaratan, Johnny memberikan Koper berisi kuncinya ke Pramugara yang ternyata adalah anggota Vortex untuk menaruhnya di kabin. Saat pertemuan, Johnny tidak Menyadari akan hilangnya kunci dan baru menyadari setelah panjang lebar menjelaskan ke Perdana mentri Cina, Johnny merasa sangat malu akan kejadian ini.Kate Sumner menyuruhnya untuk mengingat kembali kejadian di Mozambik dan menemukan anggota kedua Vortex "Karlenko", mata mata dari Rusia. Tucker mengubah nama Johnny mencadi Peter Adam agar dapat masuk ke dalam pertandingan Golf di luar London dimana Karlenko menjadi salah satu pesertanya. Saat bermain golf, pembunuh yang sama dari Hongkong datang dan menembak Karlenko, Johnny dan Tucker selamat dan segera membawa Karlenko ke rumah sakit, setelah sampai, Karlenko memberi tahu bahwa anggota terakhir Vortex yang mencoba membunuh Perdana Mentri Cina ada di M17, kemudia dia tewas.Saat makan malam, Johnny berbicara kepada Simon tentang adanya pengkhianat di M17, mendengar itu, Simon siap membunuh Johnny secara diam diam. Tucker menyuruh Johnny dan Simon untuk pergi ke kamar mandi, di kamar mandi, Tucker menjelaskan bahwa Simon adalah aggota terakhir Vortex, tetapi Johnny tak percaya dan menyuruh Tucker pergi. Saat di luar kamar mandi, Simon membohongi Johnny bahwa quartemain lah pelakunya, Johnny percaya sehingga dia memberikan kuncinya ke Simon. Saat dia mendesak Quartemain untuk mengakui perbuatannya, quartemain Justru menuduh Johnny lah pelakunya dan menyuruh para anggota M17 menangkapnya. Saat mencoba kabur, Johnny tertembak dikaki sehingga dia tak bisa lari, Johnny segera merebut Kursi roda Quartemain untuk kaburJohnny pergi ke rumah Kate dan meyakinkan bahwa dia bukanlah pelakunya, namun Johnny tak sadarkan diri dan langsung ditolong oleh Kate. Setelah sadar, Kate memberi tahu Johnny tentang obat yang digunakan Vortex bernama timoxelyn barbebutenol yang memungkinkan mereka untuk mengontrol seseorang sebelum orang tersebut meninggal.Johnny segera menemui Tucker dan menyuruhnya untuk kembali bergabung, Tucker yang sempat kesal akhirnya bergabung lagi bersama Johnny. Setelah sampai di markas Vortex, Johnny segera mencari Simon dan berbicara kepadanya tentang obat tersebut sehingga tanpa sadar Johnny meminum minuman yang telah dimasuki obat. Sebelum sempat dikontrol oleh Simon, Johnny sempat mencoba melawan Namun Gagal.Di saat Simon sudah mulai mengontrol Johnny untuk membunuh Perdana Mentri Cina, Tucker dan Kate mencoba memutus komunikasi antara Simon dan Johnny. Sebelum menembak Perdana mentri Cina, Johnny mengingat kata kata yang diberitahu oleh gurunya di Tibet yang berbunyi " Biarkanlah dirimu yang mengendalikannya", Johnny mencoba melawan sehingga Simon kesal dan tanpa sadar membuat penyamarannya terbongkar dengan menyebut Nama nya saat menyuruh Johnny untuk menarik pelatuknya, Johnny segera berpaling dari hadapan Perdana Mentri Cina dan segera menembak ke arah Simon yang berhasil melarikan Diri.Karena pengaruh obat, Jantung Johnny hampir berhenti berdetak sehingga dia tak sadarkan diri, Paramedis segera menolong Johnny yang denyut jantungnya makin melemah, sayangnya denyut jantung Johnny berhenti dengan Cepat.Kate segera menghampiri Johnny dan mencium Johnny, Kate segera memeriksa keadaan Johny dan tiba tiba Johnny bilang "Ya,tinggal sedikit lagi" Di antara sadar dan tidak, Kate lega karena Johnny kembali hidup lalu mencium Johnny lagi. Tucker segera memeriksa denyut Jantung Johnny dan ternyata jantung Johnny berdetak cepat. Setelah benar benar sadar, Johnny berterimakasih pada Kate dan TuckerMengetahui Simon melarikan diri, Johnny segera menerjunkan diri ke arak mobli salju dengan parasut dan segera mengejar Simon, saat Johnny sudah berada di Gondola Simon, Johnny terlibat perkelahian dengan Simon dan sayangnya Johnny terjatuh dari Gondola dan mendarat di salju. Johnny segera membuka salah satu alat M17 yaitu payung penahan peluru, ternyata itu hanya payung biasa. Melihat itu, Tucker segera memperingatinya bahwa itu adalah payung Roket. Johnny segera menggunakan payung itu dan berhasil membunuh Simon, Johnny sangat lega dan memuji Tucker dengan mengatakan "Tucker, kau anak yang cerdas"Kembali ke London, Johnny mendapat gelar ksatria oleh Ratu yang ternyata adalah sang pembunuh dari Hongkong yang ingin membunuh English, saat Johnny ingin menangkapnya, dia segera melarikan diri, Johnny melihat dia di Lorong dan segera memukuli dan menangkapnya. Setelah dia menangkap si pembunuh di depan Pegasus, 2 orang penjaga membawa sang pembunuh yang asli, melihat itu, Johnny segera sadar siapa yang dia pukuli dan merasa sangat khawatir, Johnny sadar bahwa yang dia pukuli adalah Ratu asli.

Eight years after the first fim, Johnny English practicing martial arts in Tibet to atone for his sins because of a failed mission in Mozambique. Five years later, M17 ask Johnny back to join them.Johnny returned to London to M17 headquarters and assigned by Pegasus to stop the plot to kill the Prime Minister of China. Johnny also met a fellow agent named Simon Ambrose and M17 owners named patch Quartermain. He was also assigned to a junior agent named Colin TuckerIn Hong Kong, Johnny met with former CIA agent named Tutis Fisher who is a member of "Vortex" who abandon his mission in Mozambique and one of them is the murderer of Prime Minister of China, Titus provide a key league and say that if one key is lost, then toast Vortex. But Titus was killed by a sniper paid mimetic and the keys fall into the hands of one member of the Vortex, the pursuit took place with exciting assisted with advanced equipment provision of M17, the key fortunate secured.When flying back to London, Johnny is very quiet and towards the landing, Johnny gives Suitcase contains the key to the steward who apparently is a member Vortex to put it in the cabin. When the meeting, Johnny was not aware about the loss of a key and only realized after lengthy to explain to the Prime Minister of China, Johnny felt very embarrassed by this incident.Kate Sumner told him to recall the events in Mozambique and found the second member of Vortex "Karlenko", spies from Russia. Tucker rename Johnny mencadi Peter Adam in order to get into the game Golf outside London where Karlenko become one of the participants. When playing golf, the same killer from Hong Kong to come and shoot Karlenko, Johnny and Tucker Karlenko survived and immediately brought to the hospital, after arriving, Karlenko told that the last member of Vortex are trying to kill the Prime Minister of China is on the M17, later she died.At dinner, Johnny spoke to Simon about the existence of a traitor in M17, hear it, Simon ready to kill Johnny secretly. Tucker told Johnny and Simon to go to the bathroom, in the bathroom, Tucker explained that Simon was the last aggota Vortex, but Johnny did not believe and told Tucker go. When outside the bathroom, Simon lied to Johnny that quartemain was the culprit, Johnny believes that he gave the key to Simon. When he urged Quartemain to confession, accused precisely quartemain Johnny was the culprit and told the members of the M17 catch. While trying to escape, Johnny shot the foot so that he could not run, Johnny immediately seize Wheelchairs Quartemain to blurJohnny went to her house and assured that he is not the culprit, but Johnny was unconscious and directly helped by Kate. Once aware, she tells Johnny about medications used Vortex named timoxelyn barbebutenol which allows them to control a person before the person died.Johnny immediately see Tucker and told him to re-join, Tucker who was annoyed eventually join again with Johnny. After arriving at the headquarters of the Vortex, Johnny immediately seek Simon and talk to him about the drug so unknowingly drinking Johnny has entered a drug. Before he could be controlled by Simon, Johnny had tried to fight But Failed.At the time Simon has begun to control Johnny to kill the Prime Minister of China, Tucker and Kate tried to cut off communication between Simon and Johnny. Before shooting the Prime Minister of China, Johnny remember the words that were told by his teacher in Tibet, which reads: "Let yourself that control", Johnny tried to fight so Simon upset and unconsciously make the disguise uncovered by calling his name when asked Johnny to pull the trigger, Johnny immediately turned away from the presence of the Prime Minister of China and immediately fired at Simon who managed to escape the Self.Because of the influence of drugs, Johnny's heart almost stopped beating that he was unconscious, paramedics immediately help Johnny weakened heart rate, heart rate unfortunately stopped by Johnny Quick.She immediately went and kissed Johnny Johnny, Kate immediately check on Johnny and suddenly Johnny said "Yes, stay a little longer" In between conscious and not, she was relieved that Johnny came back to life and kisses Johnny again. Tucker immediately check the heart rate and it turns out Johnny Johnny heart beat fast. After really conscious, Johnny grateful to Kate and TuckerKnowing Simon escape, Johnny immediately threw himself into the wine Mobli snow with a parachute and immediately pursue Simon, when Johnny was in Gondola Simon, Johnny got into a fight with Simon and unfortunately Johnny fell from the Gondola and landed in the snow. Johnny soon open one of the tools that umbrella holder M17 bullets, it was just a regular umbrella. Seeing that, he immediately warned that it is an umbrella rocket. Johnny immediately using the umbrella and managed to kill Simon, Johnny was very relieved and praised Tucker said "Tucker, you're a smart kid"Back to London, Johnny gets a knighthood by the Queen which was the killer from Hong Kong who wanted to kill the English, while Johnny wants to catch him, he immediately fled, Johnny saw her in the hallway and immediately beat and arrested him. After she catches the killer in front of Pegasus, 2 guards bring the killer of the original, see it, Johnny soon realized who he beat and feel very worried, Johnny realized that he beat was the original queen.