INTERPRETASI HEMATOLOGY!

PEMERIKSAAN BAYI/ANAK-ANAK LAKI-LAKI PEREMPUAN MENINGKAT MENURUNSel Darah Merah 3.5 – 5.1 x 106 /mm3 4.2 – 5.4 x

106 /mm34.7 – 6.1 x 106 /mm3

Chronic lung disease Congenital heart disease Cor pulmonale Dehydration High altitude Hypoxia (chronic) Polycythemia vera Tumors Drugs: Corticosteroids,

danazol, mycopenolate, thiazides

Addison’s disease Alcohol abuse Anemia of chronic disease Bone marrow suppression Chronic infection Chronic renal failure Hemoglobinopathies Hemolysis Hemorrhage Iron deficiency anemia Liver disease Megaloblastic anemia Myelodysplasia Normocytic anemia Renal failure (chronic) Reticulocytosis Sideroblastic anemia Drugs: Acetaminophen,

allopurinol, amphetamines, chemotherapy, digoxin, streptokinase

Hemoglobin *Hbf: <2 %

Menurun: Hemolytic anemia Meningkat: Aplastic anemia;

thalassemia major/minor; leukemia; megaloblastic anemia; paroxysmal nocturnal; hemoglobinuria; sickle cell anemia

13 – 18 g/dL

*Hgb, serum: 1 – 4 mg/dL

12 – 16 g/dL

Pregnant: > 11 g/dL

Burns COPD Dehydration Exogenous EPO Pheochromocytoma Polycythemia vera vomiting

Microcytic anemia: iron deficiency (late), Thalassemia; normocytic anemia; acute blood loss

Anemia of chronic disease Fluid volume excess Hemolytic anemia Iron deficiency (early);

macrocytic anemia: liver disease Defisiensi: Vitamin B; folate

deficiency

*HbA1c: 4 – 5.9 % Menurun: Acute blood loss Meningkat: Poor glucose control in

diabetics

Hematokrit 31 – 43 % 42 – 52 % 37 – 48 % Burns Congenital heart disease

microcytic anemia

By: Ahmad Rahmat Ramadhan, Mohammad Fadhil, Reza Aditya, Lestari Irawan Hadi, Muh. Caesar Bornie Agustio Putra Hutabarat, Slamet Wahid Kastury.

COPD Dehydration Exogenous EPO Pheochromocytoma Polycythemia vera Erythrocytosis Secondary polycythemia Shock vomiting

iron deficiency (late) thalassemia bone marrow suppression chronic infection normocytic anemia acute blood loss hemorrhage anemia of chronic disease fluid volume excess hemolytic anemia iron deficiency (early) macrocytic anemia liver disease

MCV - 80 – 100 fl 80 – 100 fl

Alcoholism Folate deficiency Hemochromatosis Liver disease Rheumatoid arthritis Vitamin B12 deficiency

Anemia of chronic disease Hereditary Spherocytosis Iron deficiency sideroblastic Anemia Thalassemia

MCH

26.0 – 34.0 pg/cell

Alcoholism Folate deficiency Hemochromatosis Liver disease rheumatoid

arthritis Vitamin B12 deficiency

Anemia of chronic disease Iron deficiency anemia Lead poisoning Sideroblastic anemia thalassemia

MCHC 31.0 – 37.0 g/dL

Infancy anemia of chronic disease

Spherocytosis

Anemia of chronic disease Spherocytosis iron deficiency

anemia Lead poisoning Sideroblastic anemia Thalassemia

RDW 11.5 – 14.5 % Iron Deficiency Anemia -

Sel Darah Putih 9.0 – 30 x 103 /uL 4.1- 10.9 x 103 /uL Anemia Autoimmune systemic

disease

Aplastic anemia Bone marrow failure Collagen vascular disease

Burns Cancer Inflammatory disease Infection Leukemia Severe stress

Ethanol Hypersplenism sepsis Deficiency: vitamin B. Folate Drugs: Chloramphenicol

Neutrofil 6 – 26 x 10 /L 54 – 62 % WBC

Acute stress Diabetic ketoacidosis Infections Inflammation Tumors

Aplastic anemia Chemotherapy Deficiency: Vitamin B, Folate Marrow infiltration Drugs: Antithyroid drugs,

chloramphenicol, sulfonamide

Limfosit 2 – 11 x 10/L 25 – 33 % WBC

Adrenal insufficiency Allergy reactions Autoimmune diseases Chronic infections Drug reactions CLL Infectious hepatitis Infection mononucleosis Thyrotoxicosis Viral infections

AIDS HIV Aplastic anemia Hemotherapy Congenital immunodeficiency

states Exogenous ACTH Hodgkins lymphoma Leukemia Radiation therapy Sepsis SLE

Monosit 0.4 – 3.1 x 10 /L 2 – 8 %

Cancer Inflammation Infection Myeloproliferative disorders Tuberculosis

Bacterial infection (overwhelming)

Basofil < 0.64 x 10 /L 0.5 – 1 % Certain skin disease Chicken pox Chronic myelogenous

leukemia Chronic sinusitis

Acute infection Adrenocortical stiumulation Grave’s disease Irridation Pregnancy

Irridation Measles Myeloproliferative disorders Myxedema Postsplenectomy Ulcerative colitis

Shock Stress

Platelet 150 – 400 x 10 /L

Acute blood loss Cancer CML Essential thrombocytopenia Infection Iron deficiency Myelofibrosis Pre-eclampsia Polycythemia vera Post-splenectomy

Alcohol Aplastic anemia Bone marrow

infiltration/replacement/suppresion

Chemotherapy DIC Evan’s syndrome Fanconi anemia HIV Hyperplasnism ITP Wiskott-Aldrich syndrome Drugs: Chepalosporin,

clopidagrel HIT Quinidine

MPV 7.5 - 11.5 fL

Deficiency: folate, vitamin B

Immune thrombocytopenia Massive hemorrhage Myelogenous leukemia Valvular heart disease

Aplastic anemia Chemotherapy induced

myelosuppression Wiskott-aldrich syndrome