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REFERATREFERAT

PENYAKIT GINJAL KRONIK PENYAKIT GINJAL KRONIK

((CHRONIC KIDNEY DISEASECHRONIC KIDNEY DISEASE

))

PEMBIMBING:PEMBIMBING:

dr. SURYANTINI, Sp.PDdr. SURYANTINI, Sp.PD

dr. WIDODO, Sp.PDdr. WIDODO, Sp.PD

DISUSUN OLEH:DISUSUN OLEH:

AKBAR FADHELIAKBAR FADHELI

KEPANITRAAN KLINIK ILMU PENYAKIT DALAMRSAU ESNAWAN ANTARIKSA

PERIODE 716 MARET – MEI !1"PROGRAM STUDI PENDIDIKAN DOKTER

FAKULTAS KEDOKTERAN UNI#ERSITAS TRISAKTI $AKARTA, MEI !1%

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PENYAKIT GINJALPENYAKIT GINJALKRONIK KRONIK

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ANATOMI GINJALANATOMI GINJAL

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PENDARAHAN GINJALPENDARAHAN GINJAL

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NEFRONNEFRON

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FUNGSI GINJALFUNGSI GINJAL

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FISIOLOGI GINJALFISIOLOGI GINJAL

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DEFINISI PENYAKIT GINJALDEFINISI PENYAKIT GINJAL

KRONISKRONIS S&'(& pr)*+* p'()*)-)/* d+0'0 +(/)-)/S&'(& pr)*+* p'()*)-)/* d+0'0 +(/)-)/

'0 2+r''3, 3+0'4/2'(4'0 p+0&r&0'0'0 2+r''3, 3+0'4/2'(4'0 p+0&r&0'0

5&0*/ /0'- '0 pr)r+*/5 d'0 p'd'5&0*/ /0'- '0 pr)r+*/5 d'0 p'd'&3&30' 2+r'4/r d+0'0 ''- /0'-.&3&30' 2+r'4/r d+0'0 ''- /0'-.

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FAKTOR RESIKOFAKTOR RESIKO

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KLASIFIKASIKLASIFIKASI

89 p'd' p+r+3p&'0 d/4'-/4'0 !,"89 p'd' p+r+3p&'0 d/4'-/4'0 !,"

LFG ;3-<30(<1,7=39 >

;1%! – &3&r9 ? 2+r'( 2'd'07 ? 4r+'(/0/0 p-'*3' ;3<d-9

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EPIDEMIOLOGIEPIDEMIOLOGI

D/ A3+r/4' S+r/4'(D/ A3+r/4' S+r/4'( 1@@"1@@@1@@"1@@@ 1!! 4'*&*1!! 4'*&*

p+r&(' p+0d&d&4 p+r('&0, d'0 '04' /0/p+r&(' p+0d&d&4 p+r('&0, d'0 '04' /0/

3+0/04'( *+4/('r *+(/'p ('&00'.3+0/04'( *+4/('r *+(/'p ('&00'.

World Health OrganizationWorld Health Organization ;WHO9;WHO9 2'C'2'C'

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!! 3+0/d'p p+0'4/( /0'- 4r)0/4 d'0!! 3+0/d'p p+0'4/( /0'- 4r)0/4 d'0

d/p+r4/r'4'0 &3-' /0/ '4'0 (+r&* 3+0/04'(d/p+r4/r'4'0 &3-' /0/ '4'0 (+r&* 3+0/04'(

/0' 3+-+2// '04' !! &(' p'd' ('&0 !"./0' 3+-+2// '04' !! &(' p'd' ('&0 !".

P+r0+5r/ ;P+r/3p&0'0 N+5r)-)/ I0d)0+*/'9P+r0+5r/ ;P+r/3p&0'0 N+5r)-)/ I0d)0+*/'9 ('&0 !!@ 3+0'('4'0 pr+'-+0*/ ''- /0'-('&0 !!@ 3+0'('4'0 pr+'-+0*/ ''- /0'-

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ETIOLOGIETIOLOGI

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PATOFISIOLOGIPATOFISIOLOGI

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ANAMNESISANAMNESIS

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PENATALAKSANAANPENATALAKSANAAN

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=.=. M+3p+r-'32'( p+32&r&4'0 '('& pr)r+*//('*M+3p+r-'32'( p+32&r&4'0 '('& pr)r+*//('*

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Pencegahan dan TerapPencegahan dan TerapTerhadap K!nd" K!#!r$dTerhadap K!nd" K!#!r$d

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Mengha#$a% Pe#$&r&'anMengha#$a% Pe#$&r&'anF&ng" GnaF&ng" Gna

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Pencegahan dan TerapPencegahan dan Terap

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Pencegahan dan TerapPencegahan dan TerapTerhadap Pen*a'%Terhadap Pen*a'%

Kard!+a"'&arKard!+a"'&ar

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4'rd/)'*4&-'r.4'rd/)'*4&-'r.

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p+0+d'-/'0 d/'2+(+*, p+0+0d'-/'0p+0+d'-/'0 d/'2+(+*, p+0+0d'-/'0

/p+r(+0*/, p+0+0d'-/'0 d/*-/p/d+3/',/p+r(+0*/, p+0+0d'-/'0 d/*-/p/d+3/',

p+0+0d'-/'0 '0+3/', p+0+0d'-/'0p+0+0d'-/'0 '0+3/', p+0+0d'-/'0

/p+r5)*5'(+3/' d'0 (+r'p/ (+r'd'p/p+r5)*5'(+3/' d'0 (+r'p/ (+r'd'p4+-+2/'0 '/r'0 d+0'0 '0&'04+-+2/'0 '/r'0 d+0'0 '0&'0

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h d P h d T

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Pencegahan dan TerapPencegahan dan TerapTerhadap K!#p'a"Terhadap K!#p'a"

P+0'4/( /0'- 4r)0/4 3+0'4/2'(4'0P+0'4/( /0'- 4r)0/4 3+0'4/2'(4'0

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/0'- '0 (+r'd/./0'- '0 (+r'd/.

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O*(+)d/*(r) R+0'- 3+r&p'4'0 4)3p-/4'*/O*(+)d/*(r) R+0'- 3+r&p'4'0 4)3p-/4'*/

p+0'4/( /0'- 4r)0/4 '0 *+r/0 (+r'd/.p+0'4/( /0'- 4r)0/4 '0 *+r/0 (+r'd/.

P+0'('-'4*'0''0 )*(+)d/*(r) r+0'-P+0'('-'4*'0''0 )*(+)d/*(r) r+0'-

d/-'4*'0'4'0 d+0'0 'r' 3+0'('*/d/-'4*'0'4'0 d+0'0 'r' 3+0'('*/

/p+r5)*5'(+3/' d'0 p+32+r/'0 )r3)0/p+r5)*5'(+3/' d'0 p+32+r/'0 )r3)04'-*/(r/)- ;1.";OH94'-*/(r/)- ;1.";OH9DD==9.9.

M % M %

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Menga%a"Menga%a"Hper,!",a%e#aHper,!",a%e#a

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P+32+r/'0 p+0/4'( 5)*5'(. P+0/4'( 5)*5'( '0 2'0'4 d/p'4'/P+32+r/'0 p+0/4'( 5)*5'(. P+0/4'( 5)*5'( '0 2'0'4 d/p'4'/'d'-' 'r'3 4'-*/&3, '-&3&0/&3 /dr)4*/d', 'r'3 3'0+*/&3.'d'-' 'r'3 4'-*/&3, '-&3&0/&3 /dr)4*/d', 'r'3 3'0+*/&3.G'r'3'r'3 /0/ d/2+r/4'0 *+r' )r'-, &0(&4 3+0'32'( '2*)r2*/G'r'3'r'3 /0/ d/2+r/4'0 *+r' )r'-, &0(&4 3+0'32'( '2*)r2*/5)5'( '0 2+r'*'- d'r/ 3'4'0'0. G'r'3 4'-*/&3 '0 2'0'45)5'( '0 2+r'*'- d'r/ 3'4'0'0. G'r'3 4'-*/&3 '0 2'0'4d/p'4'/ 'd'-' 4'-*/&3 4'r2)0'( ;'Od/p'4'/ 'd'-' 4'-*/&3 4'r2)0'( ;'O==9 d'0 4'-*/&3 '*+('(.9 d'0 4'-*/&3 '*+('(.

P+32+r/'0 2''0 4'-*/&3 3+3+(/4 ;P+32+r/'0 2''0 4'-*/&3 3+3+(/4 ;calcium mimetic agent calcium mimetic agent 9. A4/r9. A4/r'4/r /0/ d/4+32'04'0 *++0/* )2'( '0 d'p'( 3+0'32'('4/r /0/ d/4+32'04'0 *++0/* )2'( '0 d'p'( 3+0'32'(

r+*+p()r ' p'd' 4+-+0'r p'r'(/r)/d, d+0'0 0'3' *++-'3+rr+*+p()r ' p'd' 4+-+0'r p'r'(/r)/d, d+0'0 0'3' *++-'3+r/dr)4-)r/d'. O2'( /0/ d/*+2&( &'/dr)4-)r/d'. O2'( /0/ d/*+2&( &' calcium mimetic agent calcium mimetic agent , d'0, d'0d/-'p)r4'0 3+3p&0'/ +5+4(//('* '0 *'0'( 2'/4 *+r(' +5+4d/-'p)r4'0 3+3p&0'/ +5+4(//('* '0 *'0'( 2'/4 *+r(' +5+4*'3p/0 '0 3/0/3'-.*'3p/0 '0 3/0/3'-.

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P+32+r/'0 K'-*/(r/)- ;1.";OHD=9P+32+r/'0 K'-*/(r/)- ;1.";OHD=9

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Pe#$a%a"an -aranPe#$a%a"an -aran

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KOMPLIKASIKOMPLIKASI

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PROGNOSISPROGNOSIS

P+0'4/( p+0'4/( /0'- 4r)0/4 d+0'0P+0'4/( p+0'4/( /0'- 4r)0/4 d+0'0

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*+0d/r/.*+0d/r/.

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