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http://aph.sagepub.com/Asia-Pacific Journal of Public Health
http://aph.sagepub.com/content/early/2013/03/27/1010539513482965The online version of this article can be found at:
DOI: 10.1177/1010539513482965
published online 9 April 2013Asia Pac J Public HealthHuilan Xu, Li Ming Wen and Chris Rissel
Health or Body Weight : A Systematic ReviewThe Relationships Between Active Transport to Work or School and Cardiovascular
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What is This?
- Apr 9, 2013OnlineFirst Version of Record >>
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Asia-Pacific Journal of Public HealthXX(X) 1 –18
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Review
The Relationships Between Active Transport to Work or School and Cardiovascular Health or Body Weight: A Systematic Review
Huilan Xu, MBiostat, MPH1, Li Ming Wen, MD, MMed, PhD1,2 and Chris Rissel, MPH, PhD2
AbstractTo systematically examine the relationships between active transport to work or school and cardiovascular health, body weight, or other health outcomes, a systematic review of the literature was conducted in September 2012 using 3 electronic databases. A total of 3887 articles were screened, 30 full text articles were retrieved, and 19 articles were identified. Two reviewers independently assessed the quality of each article. The review found that active transport to work or school was significantly associated with improved cardiovascular health and lower body weight. However, the strength of the evidence varied from weak (mental health and cancer), moderate (body weight), to strong (cardiovascular health). The evidence was limited by lack of comparability of study outcomes, weak study designs, small sample sizes, and lack of experimental studies. Further research is needed to examine the effect of active transport on health using stronger research designs, including randomized controlled trials or longitudinal studies.
Keywordsepidemiology, public health, population health, evaluation, education, health promotion, air pollution and health, occupational and environmental health
Introduction
Active transport (walking, cycling, and public transport) is one component of an active lifestyle, which can be incorporated into routine daily activities.1,2 There is emerging and consistent evi-dence that active transport increases physical activity.3-7 Increased physical activity reduces mor-bidity and mortality rates from cardiovascular disease (CVD), hypertension, obesity, diabetes, respiratory disease, certain cancers, and musculoskeletal and mental health problems.8-11 Yet the evidence linking active transport directly to health outcomes has not been examined extensively, and the relationship between active transport and health remains unclear.
1Health Promotion Service, South Western Sydney & Sydney Local Health Districts, NSW Health, Australia2University of Sydney, Australia
Corresponding Author:Li Ming Wen, Health Promotion Service, South Western Sydney & Sydney Local Health Districts, Level 9, King George V Building, Missenden Road, Camperdown NSW 2050, Australia. Email: [email protected]
482965 APHXXX10.1177/1010539513482965Asia-Pacific Journal of Public HealthXu et alresearch-article2013
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2 Asia-Pacific Journal of Public Health XX(X)
We found 6 reviews that examined the health benefits of active transport,3,4,12-15 which included body weight, cardiovascular health, and all-cause mortality, for adults or school children. The reviews found that the cross-sectional nature of many studies of this kind prevented detection of a causal relationship between active transport and health outcomes.3,4,12,13,15 Lack of standardized definitions and measurements of active transport were identified by the reviews,3,4,12-14 and the use of nonobjective health outcome measures (eg, self-reported body weight) was also of con-cern.4,13 Other potential health outcomes such as cancer and mental health were not covered in the previous reviews.
To date, there have been no systematic reviews of the literature examining the impact of active transport to work or school (excluding trips for other reasons, eg, social and entertainment) on health outcomes for both adults and school children. The purpose of this review was to systemati-cally examine the relationships between active transport to work or school and body weight, cardiovascular health, and other health outcomes, including cancer, mental health, and injury, and also to update the existing evidence about health benefits of active transport for adults and school children. This review focused on the research literature from January 2002 to September 2012 because several previous reviews have already reviewed the active transport research litera-ture published before 2002.
Methods
Search Strategy
A literature search was conducted using the electronic databases (January 2002-September 2012), including MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), and Cochrane Database for Systematic Review. The studies were limited to those written in English. Included study designs were limited to randomized controlled trials (RCTs), cohort, case-control, and cross-sectional studies, and systematic reviews. Study participants were limited to school children and adults in the workforce. Active transport was defined as walking, cycling, or taking public transport to school or work and the health outcomes included body weight, cardiovascular health, cancer, mental health, injury, and general health. The search strategy used for the MEDLINE database is displayed in Table 1. A similar search strategy was used for CENTRAL and the Cochrane database. Additional manual searching was conducted for referenced articles of those published articles included in this review. Grey literature, such as unpublished studies and ongoing trials, was not included.
Study Selection
The present systematic review focused on the association between active transport (walking, cycling, and public transportation) to work or school and health outcomes. To be selected for this present review, studies had to meet 2 inclusion criteria: the study had to (1) investigate quantita-tive associations between active transport (walking/cycling/public transport) to work or school and health outcomes (excluding physical activity) and (2) be published in English with full text in a peer-reviewed journal.
The following types of studies were excluded: (1) validation studies, (2) pilot studies, (3) stud-ies investigating associations between walking or cycling and physical activity, and (4) studies investigating association between active transport and environmental health.
A total of 3887 articles were identified through database searching; 220 duplicated articles were removed, and 3635 articles were excluded by title. References of the remaining 32 articles were searched manually to identify relevance of the articles, and 16 additional articles were included. Of these 48 articles, 18 articles were excluded based on their abstracts. The remaining
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Xu et al 3
Table 1. The Search Strategy Used for Medline Database (January 2002 to September 2012).a
Database: Ovid MEDLINE(R) <1946 to September Week 3 2012>Search Strategy: 1. randomized controlled trial.tw,sh,pt. (342294) 2. randomized.ab. (240228) 3. randomly.ab. (172607) 4. cross-section*.ab. (139212) 5. cohort.ab. (179276) 6. case-control.ab. (57800) 7. systematic review.ab. (19866) 8. 1 or 2 or 3 or 4 or 5 or 6 or 7 (872264) 9. walk*.mp. (63087)10. public transport*.mp. (640)11. cycl*.mp. (894515)12. active travel*.mp. (75)13. active transport*.mp. (14152)14. active commut*.mp. (139)15. non-motori*ed.mp. (66)16. bik*.mp. (2376)17. bicycl*.mp. (26936)18. bus.mp. (1758)19. train.mp. (16175)20. 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 (1002675)21. overweight.mp. (30399)22. body weight.mp. (245450)23. obes*.mp. (175612)24. BMI.mp. (55483)25. body mass index.mp. (109948)26. heart disease*.mp. (165311)27. Cardiovascular disease*.mp. (134777)28. mental health.mp. (94583)29. injur*.mp. (677752)30. health.mp. (1652490)31. cancer.mp. (873684)32. 21 or 22 or 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 (3638739)33. adult*.mp. (4116056)34. school child*.mp. (15414)35. adolescent.mp. (1509723)36. teenager.mp. (1442)37. 33 or 34 or 35 or 36 (4568006)38. 8 and 20 and 32 and 37 (10785)39. limit 38 to (english language and humans and yr=“2002 -Current”) (6995)40. (39 not workplace injury not sport injury not biological transport not biological travel not substrate
cycling not therapy not physiology not exercise test not validation study not clinic* not built environment* not chromosome walking not Dandy-Walker Syndrome not treadmill not gait not cell).mp. (2188)
41. remove duplicates from 40 (2062)
aThe asterisk sign stands for any character(s).
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4 Asia-Pacific Journal of Public Health XX(X)
30 full texts were assessed for their eligibility, and a further 11 articles that did not meet the inclu-sion criteria were excluded. Finally, 19 articles (13 individual articles and 6 reviews, including 76 studies) were included in the present systematic review. The process of study selection is reported in Figure 1. Because of the heterogeneity of the studies, it was not possible to conduct a meta-analysis. Therefore, the results are presented descriptively.
Assessment of Included Articles
Two reviewers (HX and LMW) independently screened the study titles and abstracts and then critically appraised the selected articles. Scores for each article were given using a previously used assessment tool13 (Table 2) as a quality index. Brief summaries of all the studies included in this review are presented in Tables 3, 4, and 5.
Results
Description of Studies
The present systematic review included 4 previous systematic reviews, 2 narrative reviews, and 13 articles derived from 12 individual studies (1 study published 2 articles investigating the asso-ciation between cycling to school and cardiovascular health and body weight separately).
Figure 1. Study selection process.
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Xu et al 5
Of the 13 articles, 4 reported the association between active transport to school with body weight,16-19 1 study reported the association between active transport and both body weight and physical fitness,20 5 articles reported the association between active transport and cardiovascular health,21-25 1 article reported the association between active transport and both cardiovascular health and body weight,26 and 2 other articles reported the association with colon cancer, quality of life, and mental health respectively.27,28
Among the articles included in the previous 6 reviews, 63 studies reported the association between active travel and body weight,3,4,12,13 10 studies reported the association with cardiovas-cular health,14,15 and 3 studies reported the association with all-cause mortality.15
Therefore, the present systematic review included 88 individual studies investigating the asso-ciations between active transport to work or school and cardiovascular health, body weight, and other health outcomes.
Quality of Studies
Of 6 review articles, 4 reviews did not assess the quality of selected studies; 1 did quality assessment but did not report it, and only 1 review had developed and applied an assessment
Table 2. Quality Criteria and Specification of Scores.a
Quality Criteria Specification of Scores Score
1. Study type Cross-sectional/Case-control 0Longitudinal/RCT/Quasiexperiment 1
2. Assessment of exposure (active transport)
Walking and cycling combined, dichotomous 0Walking and cycling combined, categorical 1Walking and cycling combined, continuous 2Walking and cycling separate, dichotomous 1Walking and cycling separate, categorical 2Walking and cycling separate, continuous 3
3a. Assessment of CV health or physical fitness or other health outcomes
Self-reported, not validated 0Self-reported, validatedb 1Objectively measured,c not validated 1Objectively measured, validated 2
3b. Assessment of body weight as outcome
Self-reported 0Objectively measuredd 2
4. Sample size Too small for meaningful results (<500) 0500 to 10 000 1>10 000 2
5. Completeness of data Data available for <80% of participants or not reported
0
Data available for >80% of participants 16. Control for confounding Not controlled for confounders 0
Controlled at least for gender, age, and some proxy of SES (eg, income and education)
1
Total score Minimum 0 Maximum 10
Abbreviations: RCT, randomized controlled trial; CV, cardiovascular; SES, socioeconomic status.aAdapted from Wanner et al.13
bValidity of the instrument was examined against another measure of health outcome.cAn objective measure of health outcome was used, such as muscle endurance and functional strength.dHeight and weight were measured objectively.
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6
Tab
le 3
. A
ssoc
iatio
ns B
etw
een
Act
ive
Tra
nspo
rt t
o Sc
hool
or
Wor
k an
d Bo
dy W
eigh
t.
Aut
hor
(Dat
e)/Q
ualit
y Sc
ore
Stud
y D
esig
nSa
mpl
eA
ge (
year
s)A
ctiv
e T
rave
l C
lass
ifica
tion
Hea
lth O
utco
me
Indi
cato
rsA
djus
ted
Con
foun
ders
Mai
n Fi
ndin
gs
Ara
ngo
et a
l16
(201
1)/5
Cro
ss-
sect
iona
l54
6 C
hild
ren,
M
onte
ria,
C
olom
bia
14.8
(m
ean)
Act
ive
(wal
king
/cy
clin
g)/in
activ
e (c
ar/b
us/
mot
orcy
cle/
othe
r)
to s
choo
l
BMI
Age
, gen
der,
sch
ool
loca
tion,
PA
leve
l, sc
reen
tim
e
Chi
ldre
n w
ho a
ctiv
e tr
avel
ed t
o sc
hool
had
a lo
wer
lik
elih
ood
of b
eing
ove
rwei
ght
com
pare
d w
ith t
hose
w
ho in
activ
e tr
avel
ed t
o sc
hool
(A
OR
= 0
.5; 9
5% C
I =
0.3
-0.8
)
Men
doza
et
al17
(20
11)/
7C
ross
-se
ctio
nal
789 Ado
lesc
ents
, U
nite
d St
ates
14.4
(m
ean)
Wal
king
/cyc
ling
to
scho
ol, m
in/d
BMI z
-sco
re, w
aist
ci
rcum
fere
nce,
sk
in fo
lds
Die
tary
ene
rgy
inta
ke,
soci
oeco
nom
ic
and
dem
ogra
phic
ch
arac
teri
stic
s
Gre
ater
min
utes
of a
ctiv
e co
mm
utin
g w
ere
asso
ciat
ed w
ith lo
wer
BM
I z-s
core
and
ski
n fo
lds
(β =
−0.
07, P
= .0
46; β
= −
0.06
. P =
.29)
; gre
ater
be
fore
- an
d af
ter-
scho
ol M
VPA
exp
lain
ed p
art
of
the
rela
tions
hip
betw
een
activ
e co
mm
utin
g an
d w
aist
cir
cum
fere
nce
(Sob
el z
= −
1.98
; P =
.48)
Paba
yo e
t al
18
(201
0)/5
Long
itudi
nal
1170
Chi
ldre
n,
Que
bec,
C
anad
a
Base
line
age:
6;
follo
w-
up: 8
Act
ive(
wal
king
/cy
clin
g)/
inac
tive(
bus/
publ
ic
tran
sit/
car)
to
scho
ol
BMI z
-sco
res
Soci
oeco
nom
ic
and
dem
ogra
phic
ch
arac
teri
stic
s; m
othe
r’s
over
wei
ght/
obes
e st
atus
; m
othe
r’s
perc
eptio
n of
chi
ld’s
hea
lth a
nd
neig
hbor
hood
qua
lity
Act
ive
trav
el t
o an
d fr
om s
choo
l bot
h w
hen
in
kind
erga
rten
and
in g
rade
1 w
as p
redi
ctiv
e of
a
low
er B
MI z
-sco
re (β
= −
0.18
; P =
.05)
in g
rade
1;
act
ive
trav
el t
o an
d fr
om s
choo
l bot
h w
hen
in
kind
erga
rten
, gra
de 1
, and
gra
de 2
was
pre
dict
ive
of
a lo
wer
BM
I z-s
core
(β
= −
0.30
; P =
.003
) in
gra
de 2
Wen
et
al19
(2
010)
/4C
ross
-se
ctio
nal
1362
Chi
ldre
n,
Sydn
ey,
Aus
tral
ia
10-1
2 (r
ange
)W
alki
ng/c
ar/
publ
ic t
rans
port
/co
mbi
ned
to
scho
ol
BMI
Scre
en t
ime
Com
pare
d w
ith c
hild
ren
who
wer
e dr
iven
to
scho
ol
daily
, chi
ldre
n w
ho w
alke
d to
sch
ool d
aily
wer
e si
gnifi
cant
ly le
ss li
kely
to
be o
bese
(A
OR
= 0
.20;
95
% C
I = 0
.16-
0.74
)A
nder
sen
et
al20
(20
09)/
8C
ross
-se
ctio
nal
1249
A
dole
scen
ts,
Den
mar
k
15-1
9 (r
ange
)C
yclin
g/w
alki
ng/
trai
n or
bus
/car
or
mot
orcy
cle
to
scho
ol
BMI,
phys
ical
fit
ness
: aer
obic
po
wer
; mus
cle
endu
ranc
e;
func
tiona
l st
reng
th;
flexi
bilit
y; a
gilit
y
Gen
der
No
diffe
renc
e fo
und
in B
MI a
mon
g ad
oles
cent
s us
ing
diffe
rent
mod
els
to t
rave
l to
scho
ol; c
hild
ren
who
bic
ycle
d to
sch
ool h
ad h
ighe
r ae
robi
c po
wer
(d
iffer
ence
= 2
.34;
95%
CI =
1.4
5-3.
24),
mus
cle
endu
ranc
e (d
iffer
ence
in s
it-up
s =
2.9
7, 9
5% C
I =
0.84
-5.0
9; d
iffer
ence
in s
tatic
bac
k st
reng
th =
17.
63,
85%
CI =
9.0
3-26
.22)
, and
flex
ibili
ty (
diffe
renc
e =
3.
14; 9
5% C
I = 1
.72-
4.57
) th
an c
hild
ren
who
wal
ked
or w
ere
driv
en t
o sc
hool
(con
tinue
d)
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7
Aut
hor
(Dat
e)/Q
ualit
y Sc
ore
Stud
y D
esig
nSa
mpl
eA
ge (
year
s)A
ctiv
e T
rave
l C
lass
ifica
tion
Hea
lth O
utco
me
Indi
cato
rsA
djus
ted
Con
foun
ders
Mai
n Fi
ndin
gs
Faul
kner
et
al
(200
9)Sy
stem
atic
re
view
10 S
tudi
es
(9 o
ut 1
0 ar
e cr
oss-
sect
iona
l st
udie
s)
Scho
ol
child
ren
4 St
udie
s: u
sual
tr
avel
to/
from
sc
hool
(ca
r/cy
cle/
bus/
wal
k);
2 st
udie
s: u
sual
m
ode
of t
rans
port
9 St
udie
s:
body
wei
ght/
BMI;
1 st
udy:
pe
rcen
tage
bod
y fa
t
Not
rep
orte
dO
nly
1 st
udy
repo
rted
act
ive
com
mut
ers
havi
ng a
lo
wer
bod
y w
eigh
t; 9
stud
ies
foun
d no
diff
eren
ce
in b
ody
wei
ght/
BMI b
etw
een
activ
e an
d pa
ssiv
e co
mm
uter
s
Lee
et a
l4 (2
008)
Syst
emat
ic
revi
ew18
Stu
dies
(16
ou
t of
18
wer
e cr
oss-
sect
iona
l st
udie
s)
Scho
ol
child
ren
Act
ive
com
mut
ing:
w
alki
ng/c
yclin
g to
sc
hool
15 S
tudi
es: B
MI;
2 st
udie
s:
over
wei
ght/
obes
ity; 1
stu
dy:
perc
enta
ge b
ody
fat
Not
rep
orte
dO
nly
3 st
udie
s fo
und
a co
nsis
tent
ass
ocia
tion
betw
een
activ
e co
mm
utin
g an
d lo
wer
bod
y w
eigh
t; 5
stud
ies
foun
d si
gnifi
cant
res
ults
onl
y fo
r su
bgro
ups
of t
he s
tudy
pop
ulat
ion;
9 s
tudi
es fo
und
no s
igni
fican
t as
soci
atio
n; 1
stu
dy fo
und
a si
gnifi
cant
as
soci
atio
n be
twee
n ac
tive
com
mut
ing
and
high
er
BMI
Dav
ison
et
al12
(2
008)
Nar
rativ
e re
view
5 St
udie
s (4
ou
t of
5
wer
e cr
oss-
sect
iona
l st
udie
s)
Scho
ol
child
ren
Act
ive
com
mut
ing:
w
alki
ng/c
yclin
g to
sc
hool
BMI
Not
rep
orte
dO
nly
1 st
udy
foun
d m
iddl
e-sc
hool
-age
d yo
uth
who
w
ere
at r
isk
for
over
wei
ght
wer
e le
ss li
kely
tha
n th
ose
who
wer
e no
nove
rwei
ght
to w
alk
or c
ycle
to
sch
ool;
3 st
udie
s fo
und
no a
ssoc
iatio
n be
twee
n ac
tive
com
mut
ing
to s
choo
l and
BM
I; 1
stud
y fo
und
BMI o
f act
ive
com
mut
ers
incr
ease
d m
ore
duri
ng a
5-
mon
th p
erio
d th
an d
id B
MI o
f ina
ctiv
e co
mm
uter
sW
anne
r et
al13
(2
012)
Syst
emat
ic
revi
ew30
Stu
dies
(29
ou
t of
30
wer
e cr
oss-
sect
iona
l st
udie
s)
Adu
ltsW
alki
ng o
nly;
cy
clin
g on
ly; b
oth
wal
king
and
cyc
ling
Ove
rwei
ght/
obes
ity b
ased
on
BM
I
In a
ll, 2
5 st
udie
s ad
just
ed
conf
ound
ers
Inve
rse
asso
ciat
ion
betw
een
activ
e tr
ansp
ort
and
body
wei
ght
foun
d in
25
stud
ies;
3 s
tudi
es fo
und
no
asso
ciat
ion;
2 s
tudi
es fo
und
a po
sitiv
e as
soci
atio
n
Abb
revi
atio
ns: B
MI,
body
mas
s in
dex;
PA
, phy
sica
l act
ivity
; AO
R, a
djus
ted
odds
rat
io; C
I, co
nfid
ence
inte
rval
; MV
PA, m
oder
ate-
to-v
igor
ous
phys
ical
act
ivity
.
Tab
le 3
. (co
ntin
ued)
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8
Tab
le 4
. A
ssoc
iatio
ns B
etw
een
Act
ive
Tra
nspo
rt t
o W
ork
or S
choo
l and
Car
diov
ascu
lar
Hea
lth.
Aut
hor
(dat
e) /
Qua
lity
Scor
eSt
udy
Des
ign
Inte
rven
tion
Sam
ple
Age
(ye
ars)
AT
Cla
ssifi
catio
nH
ealth
Out
com
e In
dica
tors
Adj
uste
d C
onfo
unde
rsM
ain
Find
ings
And
erse
n et
al21
(2
011)
/6
Long
itudi
nal
No
334
Chi
ldre
n,
Ode
nse,
D
enm
ark
9.7
(mea
n)U
sual
tra
vel t
o sc
hool
(ca
r or
mot
orcy
cle/
bus
or
trai
n/bi
cycl
e/fo
ot)
CR
F; C
VD
ris
ks (
sum
of
z-sc
ores
for
sum
of s
kin
fold
s, s
ysto
lic B
P, T
C/
HD
L ra
tio, T
G, H
OM
A
and
reve
rse
of fi
tnes
s)
Gen
der
Base
line
in fi
tnes
s: c
ycle
> n
oncy
cle,
3
mL/
m−
1 /kg
−1
Follo
w-u
p: c
ycle
> n
oncy
cle
in fi
tnes
s,
2.5
mL/
m−
1 /kg
−1 ;
cycl
e <
non
cycl
e in
su
m o
f z-s
core
s, 1
.58
de G
eus
et a
l22
(200
8)/6
Qua
siex
peri
men
tal
stud
y1-
Year
cyc
ling
to
wor
k fo
r 2
to
15 k
m, a
t lea
st
3 tim
es/w
k
IG: 6
5; C
G:
15; F
land
ers,
Be
lgiu
m
IG: 4
3; C
G: 4
9 (m
ean)
Cyc
ling
to w
ork
Cor
onar
y ri
sk fa
ctor
s;
men
tal h
ealth
; qua
lity
of li
fe
Age
The
incr
ease
s in
Wm
ax, W
max
/kg,
V
O2p
eak
and
VO
2pea
k/kg
ove
r tim
e w
ere
sign
ifica
ntly
hig
her
in t
he IG
tha
n in
the
CG
Bo
uts/
wk,
exp
ende
d en
ergy
(kc
al/w
k)
wer
e si
gnifi
cant
ly h
ighe
r in
the
IG t
han
in t
he C
G
TC
, LD
L, T
C/H
DL,
and
DBP
dec
reas
ed
and
HD
L in
crea
sed
sign
ifica
ntly
in t
he
IG b
ut n
ot s
igni
fican
tly d
iffer
ent
from
th
e C
G
The
incr
easi
ng o
f vita
lity
in t
he IG
was
si
gnifi
cant
ly h
ighe
r th
an t
hat
in t
he C
G
Phys
ical
func
tioni
ng in
crea
sed
sign
ifica
ntly
ove
r tim
e in
the
wom
en
IGG
uo e
t al
23
(200
9)/7
Cro
ss-s
ectio
nal
No
1024
Adu
lts;
Beiji
ng, C
hina
75%
, 18-
49;
25%
age
d >
49.
Wal
king
/cyc
ling/
bus/
car
or t
axi
Dys
lipid
emia
(T
C, T
G)
Gen
der,
age
, ed
ucat
ion,
sm
okin
g,
drin
king
, edi
ble
oil i
ntak
e, s
alt
inta
ke, B
MI
Peop
le d
rivi
ng a
car
or
taki
ng a
tax
i and
ta
king
the
bus
to
wor
k ha
d hi
gher
pr
obab
ility
of d
yslip
idem
ia t
han
thos
e w
alki
ng t
o w
ork
(AO
R =
2.2
1, 9
5% C
I =
1.2
8-3.
84; A
OR
= 1
.99.
95%
CI =
1.
33-2
.97)
N
o di
ffere
nce
betw
een
cycl
ing
and
wal
king
Mol
ler
et a
l24
(201
1)/5
RC
T8-
Wee
k co
mm
uter
cy
clin
g
48 A
dults
; Isl
and
of F
unen
, D
enm
ark
IG: 4
4.4;
CG
: 46
(m
ean)
Min
imum
of 2
0 m
inut
es o
f da
ily c
omm
uter
cyc
ling
VO
2max
, CR
F, s
um
of s
kin
fold
s, D
BP,
sy
stol
ic B
P
Gen
der,
age
, ba
selin
e m
easu
reIn
terv
entio
n >
con
trol
in V
O2m
ax: 2
06
mL
O2/
min
Inte
rven
tion
> c
ontr
ol in
CR
F: 2
.6 m
L O
2/kg
/min
In
terv
entio
n <
con
trol
in s
um o
f ski
n fo
lds:
12.
1 m
m
(con
tinue
d)
at University of Sydney on April 10, 2013aph.sagepub.comDownloaded from
9
Aut
hor
(dat
e) /
Qua
lity
Scor
eSt
udy
Des
ign
Inte
rven
tion
Sam
ple
Age
(ye
ars)
AT
Cla
ssifi
catio
nH
ealth
Out
com
e In
dica
tors
Adj
uste
d C
onfo
unde
rsM
ain
Find
ings
N
o di
ffere
nce
betw
een
inte
rven
tion
and
cont
rol g
roup
s in
DBP
and
sys
tolic
BP
Wen
nber
g et
al25
(2
010)
/6C
ase-
cont
rol
No
Cas
e: 2
04;
cont
rol:
327;
V
aste
rbot
ten,
Sw
eden
Cas
e:51
.4;
cont
rol:
50.6
(m
ean)
Tra
vel t
o w
ork
(wal
king
, cy
clin
g, o
r bu
s ev
ery
seas
on/c
ar e
very
sea
son/
car
1 to
3 s
easo
ns)
Inci
denc
e of
MI
Smok
ing,
ed
ucat
ion,
hy
pert
ensi
on,
diab
etes
, le
isur
e tim
e PA
, oc
cupa
tiona
l PA
Adj
uste
d O
R fo
r ca
r co
mm
uter
s is
1.7
7 (9
5% C
I = 1
.05-
2.99
)T
he O
R fo
r ca
r co
mm
uter
s fr
om
med
iatio
n an
alys
is is
1.4
0 (9
5% C
I =
0.76
-2.5
7), 4
0.1%
of M
I ris
k re
late
d to
co
mm
utin
g ac
tivity
can
be
expl
aine
d by
all
risk
fact
ors
and
infla
mm
ator
y an
d he
mos
tatic
mar
kers
Hu
et a
l26
(200
2)/6
Cro
ss-s
ectio
nal
No
3976
; Tia
njin
g,
Chi
na39
.9 (
mea
n);
15-6
9 (r
ange
)
Usu
al t
rave
l to
scho
ol o
r w
ork
(0 m
inut
es: b
us o
r no
com
mut
ing;
phy
sica
l ac
tivity
, 1-3
0 m
inut
es: f
oot
or b
icyc
le, 3
1-60
min
utes
: fo
ot o
r bi
cycl
e, >
60
min
utes
: bic
ycle
)
CV
D r
isk
fact
ors:
bod
y m
ass
inde
x; D
BP;
syst
olic
BP
Age
, edu
catio
n,
smok
ing,
al
coho
l, BM
I, oc
cupa
tiona
l PA
The
like
lihoo
d of
hyp
erte
nsio
n in
crea
sed
alon
g w
ith t
he t
ime
on w
alki
ng o
r cy
clin
g to
wor
k or
sch
ool i
n bo
th
gend
ers
(tre
nd t
est,
P <
.05)
Dai
ly t
ime
on a
ctiv
e co
mm
utin
g w
as
inve
rsel
y re
late
d to
mea
n BM
I and
pr
eval
ence
of o
verw
eigh
t am
ong
men
Ham
er a
nd
Chi
da14
(20
08)
Met
a-an
alyt
ic r
evie
wN
o8
Stud
ies
(7
pros
pect
ive
coho
rt s
tudy
, 1
case
-con
trol
st
udy)
Adu
lts (
6 st
udie
s co
ntai
ned
both
men
an
d w
omen
, 2
stud
ies
wer
e m
en
only
)
5 St
udie
s: t
ime
spen
t w
alki
ng/c
yclin
g to
wor
k; 1
st
udy:
tim
e sp
ent
wal
king
to
wor
k; 1
stu
dy: w
alki
ng/
cycl
ing
to w
ork;
1 s
tudy
: w
alki
ng/c
yclin
g/bu
s/ca
r to
wor
k.
2 St
udie
s: C
HD
; 2
stud
ies:
hyp
erte
nsio
n; 1
st
udy:
CV
D m
orta
lity;
1
stud
y: s
trok
e; 1
stu
dy:
diab
etes
.
All
stud
ies
adju
sted
co
nfou
nder
sT
he o
vera
ll ri
sk r
atio
was
0.8
9 w
ith 9
5%
CI =
0.8
1-0.
98; P
= .0
16T
he p
rote
ctiv
e ef
fect
s of
act
ive
com
mut
ing
wer
e m
ore
robu
st a
mon
g w
omen
(ri
sk r
atio
= 0
.87;
95%
CI =
0.
77-0
.98;
P =
.02)
For
men
, ris
k ra
tio =
0.9
1; 9
5% C
I =
0.79
-1.0
4; P
= .1
65 Sh
epha
rd15
(2
008)
Nar
rativ
e re
view
No
2 St
udie
s1
Stud
y:
adul
ts; 1
st
udy:
sch
ool
child
ren
1 St
udy:
cyc
ling
to w
ork;
1
stud
y: c
yclin
g to
sch
ool
Inci
denc
e of
MI;
CR
FN
ot r
epor
ted
The
inci
denc
e of
MI a
mon
g th
ose
cycl
ing
to w
ork
was
onl
y ha
lf of
tha
t in
the
ge
nera
l pop
ulat
ion
Chi
ldre
n w
ho c
ycle
d to
sch
ool w
ere
subs
tant
ially
mor
e fit
tha
n th
ose
who
w
alke
d or
wer
e dr
iven
to
scho
ol
Abb
revi
atio
ns: A
T, a
ctiv
e tr
ansp
ort;
TC
, tot
al c
hole
ster
ol; I
G, i
nter
vent
ion
grou
p; L
DL,
low
-den
sity
lipo
prot
ein;
MI,
myo
card
ial i
nfar
ctio
n; C
RF,
car
dior
espi
rato
ry fi
tnes
s; H
DL,
hig
h-de
nsity
lipo
prot
ein;
CG
, co
ntro
l gro
up; D
BP, d
iast
olic
blo
od p
ress
ure;
CH
D, c
oron
ary
hear
t di
seas
e; C
VD
, car
diov
ascu
lar
dise
ase;
TG
, tri
glyc
erid
es; W
max
, max
imal
ext
erna
l pow
er A
OR
, adj
uste
d od
ds r
atio
; BP,
blo
od p
ress
ure;
H
OM
A, h
omeo
stat
ic m
odel
ass
essm
ent;
VO
2pea
k, h
ighe
st o
xyge
n up
take
; PA
, phy
sica
l act
ivity
.
Tab
le 4
. (co
ntin
ued)
at University of Sydney on April 10, 2013aph.sagepub.comDownloaded from
10
Tab
le 5
. A
ssoc
iatio
n Be
twee
n A
ctiv
e T
rans
port
to
Wor
k an
d H
ealth
Out
com
es.
Aut
hor
(dat
e) /
Qua
lity
Scor
eSt
udy
Des
ign
Sam
ple
Age
(ye
ars)
Act
ive
Tra
vel/
Com
mut
ing
PA
Cla
ssifi
catio
nH
ealth
Out
com
e In
dica
tors
Adj
uste
d C
onfo
unde
rsM
ain
Find
ings
Han
sson
et
al27
(2
011)
/6C
ross
-se
ctio
nal
21 0
88 A
dults
; Sc
ania
, Sw
eden
45 (
med
ian)
Wal
king
/cyc
ling
<30
m
inut
es; c
ar <
30
min
utes
/30-
60
min
utes
/>60
m
inut
es; b
us/t
rain
<
30 m
inut
es/3
0-60
m
inut
es/>
60 m
inut
es.
Perc
eive
d sl
eep
qual
ity,
ever
yday
str
ess,
men
tal
heal
th, s
elf-r
ated
he
alth
, vita
lity,
sic
knes
s/ab
senc
e
Gen
der,
age
, edu
catio
n,
plac
e of
bir
th,
occu
patio
nal c
lass
, job
st
rain
, ove
rtim
e, h
isto
ry
of u
nem
ploy
men
t, in
com
e, fi
nanc
ial s
tres
s,
resi
dent
ial l
ocat
ion,
fa
mily
situ
atio
n
Com
pare
d w
ith a
ctiv
e co
mm
uter
s, c
ar
com
mut
ers
in t
he 3
0- t
o 60
-min
ute
cate
gory
an
d pu
blic
tra
nspo
rt c
omm
uter
s in
the
>
60-m
inut
e ca
tego
ry w
ere
mor
e lik
ely
to
expe
rien
ce p
erce
ived
poo
r sl
eep
qual
ity
(AO
R =
1.3
7, 9
5% C
I = 1
.16-
1.62
; AO
R =
1.
41, 9
5% C
I = 1
.08-
1.85
)C
ar c
omm
uter
s in
the
30-
to
60-m
inut
e ca
tego
ry w
ere
mor
e lik
ely
to e
xper
ienc
e ev
eryd
ay s
tres
s (A
OR
= 1
.37;
95%
CI =
1.1
6-1.
62),
whe
reas
pub
lic t
rans
port
com
mut
ers
in t
he <
30-m
inut
e ca
tego
ry w
ere
less
like
ly
to e
xper
ienc
e ev
eryd
ay s
tres
s
C
ar c
omm
uter
s in
the
<30
and
30-
to
60-m
inut
e ca
tego
ries
and
pub
lic t
rans
port
co
mm
uter
s in
the
>60
-min
ute
cate
gory
wer
e m
ore
likel
y to
hav
e lo
w s
elf-r
ated
hea
lth
(AO
R =
1.1
2, 9
5% C
I = 1
.02-
1.23
; AO
R =
1.
25, 9
5% C
I = 1
.09-
1.43
; AO
R =
1.4
4, 9
5%
CI =
1.1
6-1.
80)
C
ar c
omm
uter
s in
the
<30
and
30-
to
60-m
inut
e ca
tego
ries
and
pub
lic t
rans
port
co
mm
uter
s in
30-
60 a
nd >
60 m
inut
e ca
tego
ries
wer
e m
ore
likel
y to
hav
e lo
w
vita
lity
(AO
R =
1.2
2 an
d 1.
42; A
OR
= 1
.30
and
1.55
)
Car
com
mut
ers
in t
he <
30 a
nd 3
0- t
o 60
-min
ute
cate
gori
es w
ere
mor
e lik
ely
to
have
sic
knes
s ab
senc
e >
5 d/
year
(A
OR
=
1.15
and
1.2
7)
Low
men
tal h
ealth
was
not
sig
nific
antly
as
soci
ated
with
com
mut
ing
mod
e an
d tim
e
(con
tinue
d)
at University of Sydney on April 10, 2013aph.sagepub.comDownloaded from
11
Aut
hor
(dat
e) /
Qua
lity
Scor
eSt
udy
Des
ign
Sam
ple
Age
(ye
ars)
Act
ive
Tra
vel/
Com
mut
ing
PA
Cla
ssifi
catio
nH
ealth
Out
com
e In
dica
tors
Adj
uste
d C
onfo
unde
rsM
ain
Find
ings
Hou
et
al28
(2
004)
/6C
ase-
cont
rol
Cas
e: 9
31;
cont
rol:
1552
adu
lts;
Shan
ghai
, C
hina
30-7
4 (r
ange
)M
ET h
/wk
scor
e: lo
w
(<48
.3);
med
ium
(48
.3-
94.3
); hi
gh (
>94
.3)
Col
on c
ance
rA
ge, e
duca
tion,
fam
ily
inco
me,
mar
ital s
tatu
s,
tota
l ene
rgy
inta
ke, r
ed
mea
t in
take
, car
oten
e in
take
s, fi
ber
inta
kes
Col
on c
ance
r ri
sk w
as s
igni
fican
tly r
educ
ed
amon
g th
ose
with
hig
h-co
mm
utin
g PA
(m
en,
AO
R =
0.5
2, 9
5% C
I = 0
.27-
0.87
; wom
en,
AO
R =
0.5
6, 9
5% C
I = 0
.21-
0.91
)T
hose
with
hig
h-co
mm
utin
g PA
for
at le
ast
35 y
ears
(m
en, A
OR
= 0
.34,
95%
CI =
0.
09-0
.76;
wom
en, A
OR
= 0
.31,
95%
CI =
0.
07-0
.72)
W
omen
with
2 a
dditi
onal
co
nfou
nder
s: n
umbe
r of
pr
egna
ncie
s, m
enop
ausa
l st
atus
Shep
hard
15
(200
8)
Nar
rativ
e re
view
3 st
udie
sA
dults
2 St
udie
s: c
yclin
g to
w
ork;
1 s
tudy
: wal
king
/cy
clin
g to
wor
k
All-
caus
e m
orta
lity
2 St
udie
s ad
just
ed
conf
ound
ers
All-
caus
e m
orta
lity
was
inve
rsel
y co
rrel
ated
w
ith c
yclin
g to
wor
kSp
endi
ng ≥
15 m
inut
es w
alki
ng/c
yclin
g to
wor
k w
as a
ssoc
iate
d w
ith r
educ
ed a
ll-ca
use
and
card
iova
scul
ar m
orta
lity
Abb
revi
atio
ns: P
A, p
hysi
cal a
ctiv
ity; A
OR
, adj
uste
d od
ds r
atio
; CI,
conf
iden
ce in
terv
al; M
ET, m
etab
olic
equ
ival
ent.
Tab
le 5
. (co
ntin
ued)
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12 Asia-Pacific Journal of Public Health XX(X)
tool.13 This assessment tool was adapted and used in the present systematic review (see Table 2) with criterion 3a modified to replace “physical activity” with “cardiovascular health” or “other health outcome.”
The study types of the 12 selected individual studies varied and included 2 intervention stud-ies (1 RCT and 1 quasiexperimental study, both using cycling to work as an intervention) for adults; 2 longitudinal studies for school children with follow-up periods of 2 and 6 years, respec-tively; 2 case-control studies for adults; and 6 cross-sectional studies for either school children or adults. Sample sizes of these studies were reasonable (mean sample size n = 2668), except for 2 intervention studies (n = 48 and n = 80, respectively). Most studies defined active transport as walking or cycling, but measured walking, cycling, car or motorcycle use, and public transport use (bus or train) separately. Health outcome indicators were measured objectively in all studies. The missing data were lower than 20% in most studies, and in most studies, more than 1 con-founder was adjusted for in the data analysis. Based on the quality assessment tool, the average score of 13 selected articles was relatively high: 5.92 out of 10 (minimum score = 4; maximum score = 8).
Active Transport and Body Weight
In all, 5 studies presented associations between active transport to school and school children’s body weight16-20 (Table 3). Of these, 4 were of cross-sectional design, and only 1 was a longitu-dinal study. Body weight status was assessed by body mass index (BMI) or BMI z-score or cat-egorized as overweight or obesity.
Active transport was defined as walking or cycling to school, and inactive transport was defined as using a car or motorcycle or public transport to school in 3 studies.16,18,20 Two studies found an inverse association between active transport and body weight,16,18 whereas 1 found no difference in BMI among adolescents using different modes of travel to school, but those chil-dren who bicycled to school had better physical fitness than children who walked or were driven to school.20
One study using time (minutes) of walking or cycling to school per day as an exposure factor found that greater minutes of active commuting were associated with lower BMI z-score and skin fold thickness.17 One study classified travel modes to school as walking, car, and mixed modes (including public transport) and found that compared with children who were driven to school daily, children who walked to school daily were significantly less likely to be obese.19 Another study examined the association between time walking or cycling to work and body weight and found that daily time actively commuting was inversely related to mean BMI and prevalence of overweight among men26 (Table 4). The inverse associations between active transport to work or school and body weight were consistent in these studies.
Four review articles,3,4,12,13 which included 63 studies, examined the association between active transport to work or school and body weight. Most of them (58 studies) were cross-sec-tional studies. Among these studies, 35 found that more active transport to work (n = 25) or school (n = 10) was associated with lower body weight; 24 studies found no association between active transport to work or school and body weight. Surprisingly, 4 studies found that active transport to work or school was associated with higher body weight. The evidence of inverse association between active transport to work or school and body weight derived from these 4 reviews was less consistent than that in the most recent studies.
Active Transport and Cardiovascular Health
Six studies examined the relationship between active transport and cardiovascular health.21-26 Descriptive characteristics of these studies are presented in Table 4. Various study types were
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used including cross-sectional study, case-control study, quasiexperimental study, longitudinal study, and RCT. Indicators of cardiovascular health were various, including cardiorespiratory fitness (CRF; maximal power output per kilogram, relative oxygen uptake, and maximal oxygen uptake), CVD risk factor (body fat/body weight/diastolic and systolic blood pressure/blood lip-ids/glucose/insulin), and incidence of myocardial infarction (MI). All cardiovascular health out-comes were measured objectively.
Two studies, 1 RCT24 and 1 quasiexperimental study,22 both using cycling to work as an inter-vention, found that cycling to work was associated with improved CRF, and the quasiexperimen-tal study also found that total cholesterol (TC), low-density lipoprotein (LDL), TC/LDL, and diastolic blood pressure decreased and high-density lipoprotein (HDL) increased significantly in the cycling group but not significantly different from the control group. One longitudinal study21 found that cycling to school was associated with better CRF and CVD risk factor profiles (lower TC, TG, TC/HDL, composite CVD risk factor score, and better glucose metabolism). Another study23 using blood lipids as an indicator of cardiovascular health also found that people who used inactive transport to get to work (car/taxi/bus) were more likely to have dyslipidemia than those walking to work, but there was no difference between walking and cycling after adjusting for confounders.
One case-control study25 examined the association between active commuting (walking/cycling) to work and risk of MI and explored the potential mediators. It was found that car com-muting was significantly associated with MI after adjusting for confounders, and the potential mediators explained 40% of the MI risk.
One cross-sectional study26 examined the impact of time walking or cycling to work or school on blood pressure. It found that the likelihood of hypertension increased with the time walking or cycling to work or school in both genders (trend test P < .05) after adjusting for confounders.
Two reviews14,15 that included 10 studies reported on the association between active transport and cardiovascular health. One meta-analysis14 that included 8 studies reported that walking or cycling to work was associated with an overall 11% reduction in cardiovascular risk. Two studies reviewed by Shephard15 reported that cycling to school benefited cardiovascular fitness, and the incidence of MI among those cycling to work was only half of that in the general population.
Overall, the evidence provided by these studies and reviews was quite consistent and sup-ported the hypothesis that walking or cycling to work or school improves CRF and reduces CVD risk factors. Only 1 study24 reported that there was no benefit of active transport on blood pres-sure, and 1 study26 reported a negative effect on blood pressure.
Active Transport and Other Health Outcomes
One cross-sectional study27 defined active commuters to work as those walking/cycling <30 minutes and classified car and public transport commuters into those spending <30 minutes, 30 to 60 minutes, and >60 minutes commuting. It found that compared with active commuters, car commuters were more likely to perceive poor sleep quality, experience everyday stress, have low self-rated health, have low vitality, and have sickness absence >5 days per year, whereas public commuters in the >60-minute category were more likely to experience perceived poor sleep qual-ity, have low self-rated health, and have low vitality after adjusting for confounders (see Table 5). Poor mental health was not significantly associated with commuting mode or time.
One case-control study28 examined the effect of active transport on colon cancer and found that colon cancer risk was significantly lower among active transport users, particularly among those who had used active transport for at least 35 years, after adjusting for confounders (see Table 5).
One review article15 included 3 studies dealing with the effect of active transport on mortality from China, Finland, and Denmark. The Chinese study found that among active commuters,
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all-cause mortality was less strongly associated with walking than with cycling; the Finnish study showed that spending ≥15 min/d walking or cycling to work was associated with reduced all-cause and cardiovascular mortality in women but not in men; the Danish study noted that all-cause mortality was 40% lower in cyclists than in other commuters after adjusting for self-reported leisure-time activities.
Discussion
Strengths and Weaknesses of the Available Evidence
The present systematic review supports the hypothesis that active transport was associated with positive health status in terms of cardiovascular health, body weight, and other health outcomes (including colon cancer and all-cause mortality). However, the strength of the evidence varied. The evidence linking active transport and cardiovascular health was moderate to strong. Out of 16 studies, 15 concluded that active transport to work (n = 14) or school (n = 1) was associated with better cardiovascular health. The evidence relating active transport with lower body weight was weak to moderate, with most studies being cross-sectional and lacking consistency in the study findings, although 40 of 69 studies reported that active transport was associated with lower weight. Few studies have examined the relationships between active transport to work and other health outcomes such as mental health, cancer, quality of life, and injury.
Studies examining the association between active transport and cardiovascular health pro-vided relatively stronger evidence. The evidence that active transport was associated with better cardiovascular health was consistent. Out of 16 studies examining the association between active transport and cardiovascular health, 15 concluded that active transport to work (n = 14) or school (n = 1) was associated with better CRF, lower CVD risk factors, and lower incidence of MI. Although the sample sizes for 1 RCT and 1 quasiexperimental study were small (n = 48 and 80, respectively), most other studies had reasonable sample sizes, ranging from 334 to 3976.
In contrast, the evidence for the impact of active transport on body weight was not consistent. Out of 69 studies, 40 examining the association between active transport and body weight reported that active transport to work (n = 25) or school (n = 15) was associated with lower body weight; 25 studies found no association between active transport and lower body weight, and 4 studies found that active transport to work or school was associated with higher body weight. Almost all studies were cross-sectional studies that provided weak evidence and cannot contrib-ute to the conclusion that there is a causal effect.
There is a discrepancy in the evidence generated from 6 studies included in this review and 4 previous reviews regarding the association between active transport and body weight. This could be explained by publication bias because we did not include gray literature in the present system-atic review; it could also be a result of active travel to work (walking) not being intense or long enough to have an impact on weight.
Strength and consistency are not enough to determine causality according to Hill’s criteria.29 There are 6 other criteria assessing causation: specificity, dose-response relationship, plausibility, coherence, experiment, and analogy. Therefore, no causal effect can be concluded in relation to active transport and health outcomes based on this review. For example, not all studies included in this systematic review adjusted for other potential confounders such as diet, screen time, and leisure time physical acidity. In this review, in terms of dose response, only 2 studies found that greater minutes of walking or cycling to work or school were associated with lower BMI17,26; 1 study found that the likelihood of hypertension increased along with the time walking or cycling to work or school in both genders. Thus, a dose response relationship was not convincing. Nevertheless, active transport improving health through increasing physical activity is biologi-cally plausible and coherent. Although the present review included some experimental studies
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(RCT and quasiexperimental studies), most studies included in this review were case-control or cross-sectional studies.
Few studies examined or reported the association between active transport and other health outcomes, such as mental health, cancer, and all-cause mortality, and all studies of this kind were cross-sectional or case-control studies. Therefore, these studies do not provide strong evidence.
Despite lack of causation in relation to active transport and health benefits, promoting active transport can be beneficial to human health, not only through increasing physical activity but also by reducing air pollution, road crashes, traffic congestion, and noise as a result of reduced car use.30-37 Concern that increased active transport might increase the risk of injury may not be warranted, with health benefits of active transport outweighing the injury toll. One study found that the individual injury risk per exposure hour is relatively low in active commuting (walking and cycling) when compared with recreational and competitive sports.38 Another study from the Netherlands concluded that on average, the estimated health benefits of cycling were substantially larger than the risk relative to car driving for individuals shifting their mode of transport.39
Strengths and Limitations of this Review
One of the main strengths of this review is the comprehensive and systematic inclusion and exclusion criteria and the application of a quality assessment tool. We included various study types, including RCTs, quasiexperimental studies, and longitudinal studies in this review. We focused on the actual health outcomes rather than intermediate outcomes (eg, physical activity), and most health outcomes were measured objectively, which greatly improved the quality of included studies. In addition, the present review examined the associations between active trans-port and general health outcomes specifically for school children and adults in the workforce, so that the studies included in the review have a very clearly defined measure of active transport.
However, this systematic review may be limited by the exclusion of the gray literature, and the study findings could be influenced by publication bias. This limitation was remedied by includ-ing 6 previous reviews that included some gray literature. Another limitation of this review was the inability to conduct a meta-analysis because of the heterogeneity of studies included in this review, which made it difficult to reach strong conclusions. Therefore, it is arrive at strong con-clusions and recommendations based on the current evidence.
Unanswered Questions and Future Research
In this systematic review, active transport was defined as walking, cycling, and using public transport to work or school; however, in most studies included in the review, public transport was classified as inactive transport. We believe that public transport is an important part of active transport that usually involves some walking to bus stops or train stations.2 A recent review6 reported that a range of 8 to 33 additional minutes of walking was attributed to public transport use and highlighted the fact that a greater uptake of public transport by inactive adults would likely lead to significantly greater increases in the adult population considered sufficiently active. Future research needs to focus on the effect of public transport on health.
Few studies have examined the association between active transport and a range of other health outcomes, including mental health, certain cancers, diabetes, and commuting-related injury. These also need to be explored in future research.
Furthermore, there is an obvious need for more methodologically sound studies with suffi-cient sample sizes to provide strong evidence regarding the benefits of active transport in our communities.
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Conclusions
Active transport that incorporates walking and cycling to work or school is a promising way to improve people’s health, in particular cardiovascular health, through integrating physical activity into daily life. Further research is needed to examine the effect of active transport on health using stronger research designs, such as RCTs or longitudinal studies. The effect of public transport on health needs to be further investigated.
Declaration of Conflicting Interests
The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Funding
The author(s) received no financial support for the research, authorship, and/or publication of this article.
Reference
1. Burke M, Hatfield E, Pascoe J. Urban planning for physical activity and nutrition: a review of evidence and interventions. http://www.griffith.edu.au/__data/assets/pdf_file/0006/110769/urp-rp22-burke-et-al-2008.pdf. Accessed September 20, 2012.
2. National Heart Foundation of Australia (Victorian Division). Healthy by Design: a planners’ guide to environments for active living. https://www.heartfoundation.org.au/SiteCollectionDocuments/Healthy-by-Design.pdf. Accessed September 20, 2012.
3. Faulkner GE, Buliung RN, Flora PK, Fusco C. Active school transport, physical activity levels and body weight of children and youth: a systematic review. Prev Med. 2009;48:3-8.
4. Lee MC, Orenstein MR, Richardson MJ. Systematic review of active commuting to school and chil-dren’s physical activity and weight. J Phys Act Health. 2008;5:930-949.
5. Ogilvie D, Foster CE, Rothnie H, et al. Interventions to promote walking: systematic review. BMJ. 2007;334:1204.
6. Rissel C, Curac N, Greenaway M, Bauman A. Physical activity associated with public transport use: a review and modelling of potential benefits. Int J Environ Res Public Health. 2012;9:2454-2478.
7. van Sluijs EMF, Fearne VA, Mattocks C, Riddoch C. The contribution of active travel to children’s physical activity levels: cross-sectional results from the ALSPAC study. Prev Med. 2009;48:519-524.
8. Department of Health, Physical Activity, Health Improvement and Prevention. At least five a week: evidence on the impact of physical activity and its relationship to health. http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/@dh/@en/documents/digitalasset/dh_4080981.pdf. Accessed September 20, 2012.
9. Nocon M, Hiemann T, Muller-Riemenschneider F, Thalau F, Roll S, Willich SN. Association of physi-cal activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis. Eur J Cardiovasc Prev Rehabil. 2008;15:239-246.
10. Sofi F, Capalbo A, Cesari F, Abbate R, Gensini GF. Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studies. Eur J Cardiovasc Prev Rehabil. 2008;15:247-257.
11. Wendel-Vos GC, Schuit AJ, Feskens EJ, et al. Physical activity and stroke: a meta-analysis of observa-tional data. Int J Epidemiol. 2004;33:787-798.
12. Davison KK, Werder JL, Lawson CT. Children’s active commuting to school: current knowledge and future directions. Prev Chronic Dis. 2008;5(3):A100. http://www.cdc.gov/pcd/issues/2008/jul/07_0075.htm. Accessed March 8, 2013.
13. Wanner M, Götschi T, Martin-Diener E, Kahlmeier S, Martin BW. Active transport, physical activity, and body weight in adults: a systematic review. Am J Prev Med. 2012;42:493-502.
14. Hamer M, Chida Y. Active commuting and cardiovascular risk: a meta-analytic review. Prev Med. 2008;46:9-13.
at University of Sydney on April 10, 2013aph.sagepub.comDownloaded from
Xu et al 17
15. Shephard RJ. Is active commuting the answer to population health? Sports Med. 2008;38:751-758. 16. Arango CM, Parra DC, Eyler A, et al. Walking or bicycling to school and weight status among adoles-
cents from Montería, Colombia. J Phys Act Health. 2011;8(S2):S171-S177. 17. Mendoza JA, Watson K, Nguyen N, Cerin E, Baranowski T, Nicklas TA. Active commuting to
school and association with physical activity and adiposity among US youth. J Phys Act Health. 2011;8:488-495.
18. Pabayo R, Gauvin L, Barnett TA, Nikiema B, Seguin L. Sustained active transportation is associated with a favourable body mass index trajectory across the early school years: findings from the Quebec longitudinal study of child development birth cohort. Prev Med. 2010;50:s59-s64.
19. Wen LM, Merom D, Rissel C, Simpson JM. Weight status, modes of travel to school and screen time: a cross-sectional survey of children aged 10-13 years in Sydney. Health Promot J Austr. 2010;21:57-63.
20. Andersen LB, Lawlor DA, Cooper AR, Froberg K, Anderssen SA. Physical fitness in relation to transport to school in adolescents: the Danish youth and sports study. Scand J Med Sci Sports. 2009;19:406-411.
21. Andersen LB, Wedderkopp N, Kristensen P, Moller NC, Froberg K, Cooper AR. Cycling to school and cardiovascular risk factors: a longitudinal study. J Phys Act Health. 2011;8:1025-1033.
22. de Geus B, Van Hoof E, Aerts I, Meeusen R. Cycling to work: influence on indexes of health in untrained men and women in Flanders. Coronary heart disease and quality of life. Scand J Med Sci Sports. 2008;18:498-510.
23. Guo X, Jia Z, Yang S, et al. Impact of mode of transportation on dyslipidaemia in working people in Beijing. Br J Sports Med. 2009;43:928-931.
24. Moller NC, Ostergaard L, Gade JR, Nielsen JL, Andersen LB. The effect on cardiorespiratory fit-ness after an 8-week period of commuter cycling–a randomized controlled study in adults. Prev Med. 2011;53:172-177.
25. Wennberg P, Wensley F, Johansson L, et al. Reduced risk of myocardial infarction related to active commuting: inflammatory and haemostatic effects are potential major mediating mechanisms. Eur J Cardiovasc Prev Rehabil. 2010;17:56-62.
26. Hu G, Pekkarinen H, Hanninen O, Yu Z, Guo Z, Tian H. Commuting, leisure-time physical activity, and cardiovascular risk factors in China. Med Sci Sports Exerc. 2002;34:234-238.
27. Hansson E, Mattisson K, Bjork J, Ostergren PO, Jakobsson K. Relationship between commuting and health outcomes in a cross-sectional population survey in southern Sweden. BMC Public Health. 2011;11:834.
28. Hou L, Ji BT, Blair A, Dai Q, Gao YT, Chow WH. Commuting physical activity and risk of colon cancer in Shanghai, China. Am J Epidemiol. 2004;160:860-867.
29. Hill AB. The environment and disease: association or causation? Proc R Soc Med. 1965;58:295-300. 30. Friedman MS, Powell KE, Hutwagner L, Graham LM, Teague WG. Impact of changes in transporta-
tion and commuting behaviors during the 1996 summer Olympic Games in Atlanta on air quality and childhood asthma. JAMA. 2001;285:897-905.
31. Giles-Corti B, Foster S, Shilton T, Falconer R. The co-benefits for health of investing in active trans-portation. N S W Public Health Bull. 2010;21:122-127.
32. Grabow ML, Spak SN, Holloway T, Brian S Jr, Mednick AC, Patz JA. Air quality and exercise-related health benefits from reduced car travel in the Midwestern United States. Environ Health Perspect. 2012;120:68-76.
33. Maibach E, Steg L, Anable J. Promoting physical activity and reducing climate change: opportunities to replace short car trips with active transportation. Prev Med. 2009;49:326-327.
34. Monzon A, Guerrero MJ. Valuation of social and health effects of transport-related air pollution in Madrid (Spain). Sci Total Environ. 2004;334-335:427-434.
35. Department of Transport and Department of Health UK. Active Travel Strategy. London, UK: Department of Transport; 2010. http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/documents/digitalasset/dh_113104.pdf. Accessed September 26, 2012.
36. National Institute for Health and Clinical Excellence. Promoting or creating built or nature envi-ronments that encourage and support physical activity. http://www.nice.org.uk/nicemedia/pdf/PH008Guidancev2.pdf. Accessed September 26, 2012.
at University of Sydney on April 10, 2013aph.sagepub.comDownloaded from
18 Asia-Pacific Journal of Public Health XX(X)
37. National Preventative Health Taskforce. Australia: the healthiest country by 2020. National Preventative Health Strategy: the roadmap for action. http://www.preventativehealth.org.au/internet/preventativehe-alth/publishing.nsf/Content/nphs-roadmap/$File/nphs-roadmap-1.pdf. Accessed September 28, 2012.
38. Parkkari J, Kannus P, Natri A, et al. Active living and injury risk. Int J Sports Med. 2004;25:209-216. 39. de Hartog JJ, Boogaard H, Nijland H, Hoek G. Do the health benefits of cycling outweigh the risks?
Environ Health Perspect. 2010;118:1109-1116.
at University of Sydney on April 10, 2013aph.sagepub.comDownloaded from