Teaching Cases II: CT Angiography Across the Ages - AAPM

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Technology Assessment Institute: Summit on CT Dose Teaching Cases II: CT Angiography Across the Ages: Single to 320 Slices P. Rogalla, M.D. Dept. of Medical Imaging University of Toronto

Transcript of Teaching Cases II: CT Angiography Across the Ages - AAPM

Technology Assessment Institute: Summit on CT Dose

Teaching Cases II:

CT Angiography Across the Ages:

Single to 320 Slices

P. Rogalla, M.D.

Dept. of Medical Imaging

University of Toronto

Technology Assessment Institute: Summit on CT Dose

Indication!

Technology Assessment Institute: Summit on CT Dose

~ 35-40 mSv

Technology Assessment Institute: Summit on CT Dose

Technology Assessment Institute: Summit on CT Dose

~ 0.8 mSv

Technology Assessment Institute: Summit on CT Dose

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

technical issues influencing scanning protocols

and radiation dose

CTA: outline

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

CTA: outline

Technology Assessment Institute: Summit on CT Dose

X-ray shutterX-ray shutter“over-ranging”

scanning area

additional rotation additional rotation

Technology Assessment Institute: Summit on CT Dose

scanning area

additional rotation additional rotation

X-ray shutterX-ray shutter“over-ranging”

Technology Assessment Institute: Summit on CT Dose

scanning area

additional rotation additional rotation

X-ray shutterX-ray shutter“over-ranging”

Technology Assessment Institute: Summit on CT Dose

helical pitch >3

two tubes

wide area detector

Technology Assessment Institute: Summit on CT Dose

wide area detector

16 cm16 cm

64-slice helical

additional rotation

Technology Assessment Institute: Summit on CT Dose

512, 48 cm

51

2, 4

8 c

mpixel size:

0.94 mm

. . . . . . . . . . .

0.94

slice thickness:

1 mm

Technology Assessment Institute: Summit on CT Dose

512, 48 cm

51

2, 4

8 c

m

0.94 mm

1 mm

. . . . . . . . . . .

0.94

1.0

slice thickness:

pixel size:

10 mm slices

5 mm slices

isotropic (1 mm)

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

CTA: outline

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

CTA: outline

spiral

z-axis

detector

4-slice CT

{{

25% 25%

spiral

z-axis

detector

4-slice CT

{{

10% 10%

spiral

z-axis

detector

16-slice CT

{{

5% 5%

64 x ~0.5 mm

32 x ~1.0 mm

spiral

z-axis

detector

64-slice CT

Technology Assessment Institute: Summit on CT Dose

Technology Assessment Institute: Summit on CT Dose

Bolus tracking:

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

CTA: outline

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

CTA: outline

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

13 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

8 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

5 s

40 cm

Scan time

0.5 s 16-slice CT

Collimation Pitch factor

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm125 s

Slice thickness, pitch

0.3 s 64-slice CT0.5 s 16-slice CT0.5 s 4 -slice CT

40 cm

Scan time

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT0.5 s 16-slice CT0.5 s 4 -slice CT

31 s

40 cm

Scan time

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

5 s

40 cm

Scan time

0.5 s 4 -slice CT0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT0.5 s 16-slice CT0.5 s 4 -slice CT

100 s

40 cm

Scan time

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

25 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

4 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

83 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

21 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

71 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

18 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

63 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

16 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

56 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

14 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

50 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

13 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

63 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

16 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

5 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

50 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

13 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

4 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

42 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

10 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

36 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

9 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

31 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

8 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

28 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

7 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

25 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

6 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

31 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

8 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

5 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

25 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

6 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

4 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

21 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

5 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

18 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

4 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

16 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

4 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

14 s

40 cm

Scan time

0.5 s 16-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

3 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.5 mm

1.0 mm

2.0 mm

5.0 mm

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

13 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

3 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

13 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

8 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

5 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

10 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

6 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

4 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

8 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

5 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

7 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

4 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

3 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

6 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

4 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

6 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

3 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

2 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch

0.3 s 64-slice CT

0.5 s 4 -slice CT

5 s

40 cm

Scan time

0.5 s 16-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor

Slice thickness, pitch0.5 s 16-slice CT

3 s

40 cm

Scan time

0.5 s 4 -slice CT

0.3 s 64-slice CT

0.5 mm

1.0 mm

2.0 mm

5.0 mm

0.8

1.0

1.2

1.4

1.6

1.8

2.0

0.8

1.0

1.2

1.4

1.6

1.8

2.0

3.0 mm

4.0 mm

8.0 mm

Collimation Pitch factor0.3 s 64-slice CT

0.5 s 4 -slice CTSlice thickness, pitch

2 s

40 cm

Scan time

0.5 s 16-slice CT

Scan duration, CM

Prokop, M. EJR 2000, 36: 86-96

Scan duration, CM

Bae KT, Heiken JP. In: Marincek B et al. Multislice CT 2000, 28-36

Injection speed, enhancement

http://www.ctisus.org/cta_web/12_04/12_04_Heiken/jpgs/Heiken_figure02.jpg

Source: Joachim Wildberger. Fleischmann D, Radiology 2005

0

50

100

150

200

250

300

0 20 40 60 80 100 120

time [s]

Rela

tive

En

ha

nc

em

en

t [

HU

]

2 ml / s

150 HU

Time frame: 32 s

32 s

20 40 60 80 100 120

time [s]

0

50

100

150

200

250

300

0R

ela

tive

En

ha

nc

em

en

t [H

U]

220 HU

16 s

Time frame: 16 s

4 ml / s

Injection speed, enhancement

Injection duration

Source: Joachim Wildberger 30s Injection

20s Injection

12s Injecton

8s Injection

5s Injection

3s Injection

1s Injection

0

50

100

150

200

250

300

350

0 5 10 15 20 25 30 35

Ao

rtic

En

ha

nce

me

nt (H

U)

time (after start of injection) (s)

0

50

100

150

200

250

300

350

0 5 10 15 20 25 30 35 40

Ao

rtic

En

ha

nce

me

nt (H

U)

time (after start of Injection) (s)

Saline chaser

Source: Joachim Wildberger

400

300

200

100

0 4020 8060

112 ml CM

112 ml CM

&

50 ml saline

4 cc / s

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

CTA: outline

Technology Assessment Institute: Summit on CT Dose

technical issues influencing scanning protocols

and radiation dose

difference b/w scanner generations

slice thickness, pitch, scanning times

consequences for contrast media injection

clinical examples

CTA: outline

Technology Assessment Institute: Summit on CT Dose

scanner: 4, 16, 64, 320?

tube settings, amount of contrast material?

newborn, partially corrected Fallot

suspected arterial and venous abnormalities

< 2 kg BW

scanner: 4, 16, 64, 320?

tube settings, amount of contrast material?

Technology Assessment Institute: Summit on CT Dose

0

10

20

30

40

50

60

70

80

90

0 10 20 30 40 50 60

body weight [kg]

[mA

s]

0

10

20

30

40

50

60

0 10 20 30 40 50

body weight [kg]

[mA

s]

0

50

100

150

200

250

0 10 20 30 40 50

body weight [kg]

[mA

s]

Chest

Abdomen

Head

observed mAs settings

in paediatric CT

Technology Assessment Institute: Summit on CT Dose

Exposure ~ Voltage 2.5

150 %

140 kV

100 %

120 kV

40 %

80 kV

Rel. Dose

Voltage

mAs x 2.5 at 80 kV

mA adaptation at 120 kV:

(body weight [kg] + 5) x f = mAs

f = 1 (chest), 1.5 (abdomen), 5 (head)

Exposure ~ Voltage 2.5

150 %

140 kV

100 %

120 kV

40 %

80 kV

Rel. Dose

Voltage

mAs x 2.5 at 80 kV

Technology Assessment Institute: Summit on CT Dose

80 kV, 20 mAs, 0.5 mm, 1.5 ml CM

Technology Assessment Institute: Summit on CT Dose

80 kV, 1.5 ml CM i.v.

Technology Assessment Institute: Summit on CT Dose

120 kV, 1.5 ml KM i.v.

58 y/o man

ICU:

CTA, search for emboli

64-slice, 0.5 s rotation,

0.5 mm slices,

10 s acquisition time

58 y/o man

ICU:

CTA, search for emboli

64-slice, 0.5 s rotation,

0.5 mm slices,

10 s acquisition time

58 y/o man

ICU:

CTA, search for emboli

64-slice, 0.5 s rotation,

0.5 mm slices,

10 s acquisition time

58 y/o man

ICU:

CTA, search for emboli

64-slice, 0.5 s rotation,

0.5 mm slices,

10 s acquisition time

Diagnoses:

pneumonia,

vascular calcifications,

left renal artery

occlusion

58 y/o man

ICU:

CTA, search for emboli

64-slice, 0.5 s rotation,

0.5 mm slices,

10 s acquisition time

Acute abdominal pain, known peripheral arteriosclerosis

Acute abdominal pain, known peripheral arteriosclerosis

Acute abdominal pain, known peripheral arteriosclerosis

chest pain triage

Hein PA et al. RöFo 2009

dynamic chest imaging + ventilation

Technology Assessment Institute: Summit on CT Dose

isotropic scanning technique for CTA

caveat: thin slices with 4-slice CT scanners

arterial phase: bolus tracking

scanning time dependent on slice thickness,

pitch, scanner type – influences amount and

injection speed of CM

isotropic scanning technique for CTA

Summary

caveat: thin slices with 4-slice CT scanners

arterial phase: bolus tracking

scanning time dependent on slice thickness,

pitch, scanner type – influences amount and

injection speed of CM