EXHIBIT 1 - WordPress.com

208
EXHIBIT 1

Transcript of EXHIBIT 1 - WordPress.com

EXHIBIT 1

BA

NN

ED

AN

D D

AN

GE

RO

US

SUB

STA

NC

ES

CO

MM

ON

LY

GIV

EN

TO

HO

RSE

S SE

NT

TO

SL

AU

GH

TE

R

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

1.A

cepr

omaz

ine

Ant

i-anx

iety

/tran

quili

zer

Prev

ious

ly u

sed

in h

uman

s, bu

t use

di

scon

tinue

d

See

also

Cita

k A

, Soy

sal D

D, U

çsel

R, K

arab

öcüo

glu

M, U

zel N

., Se

izure

s ass

ocia

ted

with

poi

soni

ng in

chi

ldre

n: tr

icyc

lic a

ntid

epre

ssan

t int

oxic

atio

n, P

EDIA

TRIN

T.48

(6):5

82-5

85 (2

006)

(Tw

o ch

ildre

n su

ffere

d ca

rdia

c ar

rest

from

into

xica

tion

from

ac

epro

maz

ine

and

died

.).

2.A

ceta

zola

mid

e D

iure

tic fo

r hor

ses.

Use

d to

trea

t epi

leps

y an

d be

nign

in

tracr

ania

l hyp

erte

nsio

n in

chi

ldre

n an

d ad

ults.

Ace

tazo

lam

ide

(sul

fona

mid

e) in

duce

s met

abol

ic a

lkal

osis

and

is co

ntra

indi

cate

d in

pa

tient

s with

hyp

erch

lore

mic

aci

dosis

, ang

le-c

losu

re g

lauc

oma,

kid

ney

and

liver

di

seas

e, a

nd in

pat

ient

s with

Add

ison’

s dise

ase.

Fat

aliti

es h

ave

occu

rred

(rare

) due

to

Stev

ens-

John

son

synd

rom

e (d

iffus

e ra

sh th

at sl

ough

s), t

oxic

epi

derm

al n

ecro

lysis

, fu

lmin

ant h

epat

ic n

ecro

sis, a

gran

uloc

ytos

is, a

plas

tic a

nem

ia, a

nd o

ther

blo

od

dysc

rasia

s. S

ensit

izat

ions

may

recu

r whe

n a

sulfo

nam

ide

is re

adm

inist

ered

irr

espe

ctiv

e of

the

rout

e of

adm

inist

ratio

n. I

f sig

ns o

f hyp

erse

nsiti

vity

or o

ther

serio

us

reac

tions

occ

ur, d

iscon

tinue

use

of t

his d

rug.

C

autio

n is

advi

sed

for p

atie

nts r

ecei

ving

con

com

itant

hig

h-do

se a

spiri

n an

d A

ceta

zola

mid

e, a

s ano

rexi

a, ta

chyp

nea,

leth

argy

, com

a an

d de

ath

have

bee

n re

porte

d.

http

://w

ww

.dru

gs.c

om/p

ro/a

ceta

zola

mid

e.ht

ml

3.A

crifl

avin

eBl

ue-K

ote

(topi

cal o

intm

ent,

antis

eptic

, pro

tect

ive

wou

nd

dres

sing)

http

://w

ww

.dru

gs.c

om/v

et/d

r-nay

lor-

blu-

kote

.htm

lN

ot fo

r use

on

anim

als i

nten

ded

for

food

.ht

tp://

ww

w.h

orse

supp

liesp

lus.c

om/a

ntise

ptic

s.htm

l

Acr

iflav

ine

is an

ingr

edie

nt fo

und

in B

lue-

Kot

e, w

hich

is it

self

labe

led

“not

for u

se o

n an

imal

s int

ende

d fo

r foo

d.”

The

dan

gers

for h

uman

s who

inge

st th

is su

bsta

nce

are

unkn

own.

4.A

ltren

oges

t R

egu-

Mat

e (a

ltren

oges

t/ora

l pr

oges

tin) (

grow

th p

rom

oter

) 21

CFR

§ 5

20.4

8:

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” “D

o N

ot U

se In

Hor

ses I

nten

ded

For

Hum

an C

onsu

mpt

ion.

” ht

tp://

ww

w.d

rugs

.com

/vet

/regu

-m

ate-

solu

tion.

htm

l

Act

ive

harm

ful i

ngre

dien

ts (re

sidue

): P

roge

stin.

Prog

estin

is u

sed

in th

e m

ini-p

ill to

pre

vent

con

trace

ptio

n so

pro

gesti

n co

uld

resu

lt in

an

abo

rted

fetu

s in

a pr

egna

nt w

oman

. Pr

oges

tin a

long

with

estr

ogen

s are

pro

-thro

mbo

tic m

eani

ng th

at th

ey c

ause

dee

p bl

ood

clot

s, in

clud

ing

veno

us th

rom

bosis

and

cer

ebra

l thr

ombo

sis.

http

://w

ww

.nej

m.o

rg/d

oi/fu

ll/10

.105

6/N

EJM

2001

0517

3442

007

Com

bine

d w

ith e

strog

ens,

prog

estin

incr

ease

s the

risk

of b

reas

t can

cer a

nd

card

iova

scul

ar p

robl

ems.

2

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

http

://w

ww

.whi

.org

/find

ings

/ht/e

plus

p_3y

r.php

Incr

ease

d str

oke

risk.

ht

tp://

ww

w.w

hi.o

rg/fi

ndin

gs/h

t/eal

one_

strok

e.ph

pH

UM

AN

WA

RN

ING

S Sk

in c

onta

ct m

ust b

e av

oide

d as

Reg

u-m

ate®

(altr

enog

est)

Solu

tion

0.22

% is

read

ily

abso

rbed

thro

ugh

unbr

oken

skin

. Pr

otec

tive

glov

es m

ust b

e w

orn

by a

ll pe

rson

s ha

ndlin

g th

is pr

oduc

t. P

regn

ant w

omen

or w

omen

who

susp

ect t

hey

are

preg

nant

sh

ould

not

han

dle

Reg

u-m

ate®

(altr

enog

est)

Solu

tion

0.22

%.

Wom

en o

f chi

ld

bear

ing

age

shou

ld e

xerc

ise e

xtre

me

caut

ion

whe

n ha

ndlin

g th

is pr

oduc

t. A

ccid

enta

l ab

sorp

tion

coul

d le

ad to

a d

isrup

tion

of th

e m

enstr

ual c

ycle

or p

rolo

ngat

ion

of

preg

nanc

y. D

irect

con

tact

with

the

skin

shou

ld th

eref

ore

be a

void

ed.

Acc

iden

tal

spill

age

on th

e sk

in sh

ould

be

was

hed

off i

mm

edia

tely

with

soap

and

wat

er.

http

://w

ww

.dru

gs.c

om/v

et/re

gu-m

ate-

solu

tion.

htm

l5.

Alu

min

um h

ydro

xide

St

repv

ax II

(com

pone

nt in

equ

ine

vacc

ine)

U

sed

in h

uman

s for

gas

troin

testi

nal

prob

lem

s, ul

cers

. ht

tp://

ww

w.d

rugs

.com

/vet

/stre

pvax

-ii.

htm

l

WA

RN

ING

S/PR

ECA

UTI

ON

SM

ay c

ause

con

stipa

tion.

Cau

tion

with

rena

l fai

lure

; pro

long

ed u

se m

ay re

sult

in o

r w

orse

n di

alys

is os

teom

alac

ia.

Elev

ated

tiss

ue a

lum

inum

leve

ls co

ntrib

ute

to th

e de

velo

pmen

t of d

ialy

sis e

ncep

halo

path

y an

d os

teom

alac

ia sy

ndro

mes

. C

autio

n w

ith

norm

opho

spha

tem

ic p

atie

nts;

prol

onge

d us

e m

ay re

sult

in h

ypop

hosp

hate

mia

if

phos

phat

e in

take

is in

adeq

uate

. A

DV

ERSE

REA

CTI

ON

S C

onsti

patio

n, d

ialy

sis o

steom

alac

ia, h

ypop

hosp

hate

mia

. ht

tp://

ww

w.p

dr.n

et/d

rugp

ages

/con

cise

mon

ogra

ph.a

spx?

conc

ise=1

544

Can

cau

se c

onsti

patio

n, c

onfu

sion,

loss

of a

ppet

ite, a

nd m

uscl

e w

eakn

ess.

http

://w

ww

.ncb

i.nlm

.nih

.gov

/pub

med

heal

th/P

MH

0001

056/

6.A

mik

acin

Ant

ibio

tic

21 C

FR §

529

.56

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion”

Ant

ibio

tics a

re p

oten

tially

dan

gero

us to

hum

ans w

ho e

ither

hav

e al

lerg

ies o

r se

nsiti

vitie

s to

them

. A

dditi

onal

ly, t

he u

se o

f ant

ibio

tics i

n fo

od a

nim

als,

and

the

subs

eque

nt in

gest

ion

by h

uman

s of t

hose

ani

mal

s, ha

s the

pot

entia

l to

crea

te a

ntib

iotic

resi

stan

ce in

hum

ans,

whi

ch c

an c

ause

sign

ifica

nt p

robl

ems

for h

uman

s upo

n su

bseq

uent

illn

ess.

7.A

mox

icill

in

Ant

ibio

tic

Infe

ctio

ns a

nd In

festa

tions

: M

ucoc

utan

eous

can

didi

asis.

G

astro

inte

stina

l: N

ause

a, v

omiti

ng, d

iarrh

ea, b

lack

hai

ry to

ngue

, and

he

mor

rhag

ic/p

seud

omem

bran

ous c

oliti

s. O

nset

of p

seud

omem

bran

ous c

oliti

s sy

mpt

oms m

ay o

ccur

dur

ing

or a

fter a

ntib

iotic

trea

tmen

t. H

yper

sens

itivi

ty R

eact

ions

: A

naph

ylax

is Se

rum

sick

ness

-like

reac

tions

, ery

them

atou

s mac

ulop

apul

ar ra

shes

, ery

them

a m

ultif

orm

e, S

teve

ns-J

ohns

on sy

ndro

me,

exf

olia

tive

derm

atiti

s, to

xic

epid

erm

al

necr

olys

is, a

cute

gen

eral

ized

exa

nthe

mat

ous p

ustu

losis

, hyp

erse

nsiti

vity

vas

culit

is an

d ur

ticar

ia h

ave

been

repo

rted.

Li

ver:

A m

oder

ate

rise

in A

ST (S

GO

T) a

nd/o

r ALT

(SG

PT) h

as b

een

note

d, b

ut th

e sig

nific

ance

of t

his f

indi

ng is

unk

now

n. H

epat

ic d

ysfu

nctio

n in

clud

ing

chol

esta

tic

3

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

jaun

dice

, hep

atic

cho

lesta

sis a

nd a

cute

cyt

olyt

ic h

epat

itis h

ave

been

repo

rted.

H

emic

and

Lym

phat

ic S

yste

ms:

Ane

mia

, inc

ludi

ng h

emol

ytic

ane

mia

, th

rom

bocy

tope

nia,

thro

mbo

cyto

peni

c pu

rpur

a, e

osin

ophi

lia, l

euko

peni

a, a

nd

agra

nulo

cyto

sis h

ave

been

repo

rted

durin

g th

erap

y w

ith p

enic

illin

s. T

hese

reac

tions

ar

e us

ually

reve

rsib

le o

n di

scon

tinua

tion

of th

erap

y an

d ar

e be

lieve

d to

be

hype

rsen

sitiv

ity p

heno

men

a.

Cent

ral N

ervo

us S

yste

m:

Rev

ersib

le h

yper

activ

ity, a

gita

tion,

anx

iety

, ins

omni

a,

conf

usio

n, c

onvu

lsion

s, be

havi

oral

cha

nges

, and

/or d

izzi

ness

hav

e be

en re

porte

d ra

rely

. M

iscel

lane

ous:

Too

th d

iscol

orat

ion

(bro

wn,

yel

low

, or g

ray

stain

ing)

has

bee

n ra

rely

re

porte

d. M

ost r

epor

ts oc

curre

d in

ped

iatri

c pa

tient

s. D

iscol

orat

ion

was

redu

ced

or

elim

inat

ed w

ith b

rush

ing

or d

enta

l cle

anin

g in

mos

t cas

es.

http

://w

ww

.dru

gs.c

om/sf

x/am

oxic

illin

-sid

e-ef

fect

s.htm

l8.

Am

pici

llin

sodi

um

Ant

ibio

tic fo

r tre

atm

ent o

f re

spira

tory

trac

t inf

ectio

ns

(pne

umon

ia a

nd st

rang

les)

and

skin

an

d so

ft tis

sue

infe

ctio

ns (a

bsce

sses

an

d w

ound

s), w

hen

caus

ed b

y su

scep

tible

org

anism

s.

21 C

FR §

522

.90c

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

CO

MM

ON

SID

E EF

FEC

TS

Infla

mm

atio

n an

d re

dnes

s of t

he to

ngue

; irri

tatio

n of

mou

th o

r thr

oat;

mild

dia

rrhea

; na

usea

; sec

ond

infe

ctio

n; v

omiti

ng.

SEV

ERE

SID

E EF

FEC

TS

Seve

re a

llerg

ic re

actio

ns (r

ash;

hiv

es; i

tchi

ng; d

iffic

ulty

bre

athi

ng; t

ight

ness

in th

e ch

est;

swel

ling

of th

e m

outh

, fac

e, li

ps, o

r ton

gue)

; blo

ody

stool

s; se

vere

dia

rrhea

; sto

mac

h pa

in/c

ram

ps; v

agin

al ir

ritat

ion

or d

ischa

rge.

ht

tp://

ww

w.d

rugs

.com

/sfx/

ampi

cilli

n-sid

e-ef

fect

s.htm

l

See

also

side

effe

cts f

or a

mpi

cilli

n in

ject

ion:

•u

pset

stom

ach,

dia

rrhea

, vom

iting

, mild

skin

rash

M

ore

seve

re:

•s

ever

e sk

in ra

sh, i

tchi

ng, h

ives

, diff

icul

ty b

reat

hing

or s

wal

low

ing,

whe

ezin

g,

unus

ual b

leed

ing

or b

ruisi

ng, h

eada

che,

diz

zine

ss, s

eizu

res,

sore

mou

th o

r thr

oat

http

://w

ww

.nlm

.nih

.gov

/med

linep

lus/d

rugi

nfo/

med

s/a60

1133

.htm

l

Mat

eria

l Saf

ety

Dat

a Sh

eet (

“MSD

S”) f

or a

mpi

cilli

n so

dium

salt:

To

xic

Effe

cts o

n H

uman

s: H

azar

dous

in c

ase

of in

gesti

on, o

f inh

alat

ion.

ht

tp://

ww

w.sc

ienc

elab

.com

/msd

s.php

?msd

sId=

9925

610

9.A

spir

in

Asp

ir-pa

ste

http

://w

ww

.drs

foste

rsm

ith.c

om/1

/1/1

0913

-asp

ir-pa

ste-b

y-or

al-x

.htm

lR

educ

es jo

int,

mus

cle,

and

lam

enes

s pa

in.

WA

RN

ING

S/PR

ECA

UTI

ON

SA

void

in c

hild

ren

or te

enag

ers f

or c

hick

enpo

x or

flu

sym

ptom

s; R

eye’

s syn

drom

e m

ay o

ccur

. M

ay c

ause

seve

re a

llerg

ic re

actio

n (h

ives

, fac

ial s

wel

ling,

asth

ma,

shoc

k)

and

stom

ach

blee

ding

. Avo

id in

asth

ma,

stom

ach

prob

lem

s tha

t per

sist o

r rec

ur,

ulce

rs, o

r ble

edin

g pr

oble

ms.

AD

VER

SE R

EAC

TIO

NS

A

llerg

ic re

actio

n, h

ives

, fac

ial s

wel

ling,

asth

ma,

shoc

k.

http

://w

ww

.pdr

.net

/dru

gpag

es/c

onci

sem

onog

raph

.asp

x?co

ncise

=195

4

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

Can

cau

se e

xces

sive

blee

ding

in th

ose

taki

ng w

arfa

rin;

http

://str

oke.

ahaj

ourn

als.o

rg/c

onte

nt/4

0/5/

1944

.full

Seve

re a

llerg

ic re

actio

ns (r

ash;

hiv

es; i

tchi

ng; d

iffic

ulty

bre

athi

ng; t

ight

ness

in th

e ch

est;

swel

ling

of th

e m

outh

, fac

e, li

ps, o

r ton

gue)

; bla

ck o

r blo

ody

stool

s; co

nfus

ion;

di

arrh

ea; d

izzi

ness

; dro

wsin

ess;

hear

ing

loss

; rin

ging

in th

e ea

rs; s

ever

e or

per

siste

nt

stom

ach

pain

; unu

sual

bru

ising

; vom

iting

. ht

tp://

ww

w.d

rugs

.com

/sfx/

aspi

rin-s

ide-

effe

cts.h

tml

10.

Ave

rmec

tin A

1a, 5

-O-

dem

ethy

l-25-

de(1

-m

ethy

lpro

pyl)-

22,2

3-di

hydr

o-25

-(1-

met

hyle

thyl

)-

Farn

am Iv

erca

re (d

ewor

mer

) ht

tp://

msd

s.far

nam

.com

/m00

1116

.ht

m Iver

care

Pas

te is

labe

led

“Do

not u

se

in h

orse

s int

ende

d fo

r foo

d pu

rpos

es.”

http

://w

ww

.dru

gs.c

om/v

et/iv

erca

re-

paste

-1-8

7.ht

ml

A h

azar

dous

com

pone

nt o

f the

Far

nam

Iver

care

dew

orm

er p

rodu

ct.

http

://m

sds.f

arna

m.c

om/m

0011

16.h

tmLi

nks t

o th

e to

xico

logi

cal l

itera

ture

her

e:

http

://pu

bche

m.n

cbi.n

lm.n

ih.g

ov/su

mm

ary/

sum

mar

y.cg

i?sid

=141

45#x

50ht

tp://

toxn

et.n

lm.n

ih.g

ov/c

gi-b

in/si

s/sea

rch/

r?db

s+to

xlin

e:@

term

+@rn

+651

95-5

1-9+

@O

R+@

all

11.

Ben

zyl a

lcoh

ol

Equi

poise

Equi

poise

Inje

ctab

le

http

://w

ww

.dru

gs.c

om/v

et/e

quip

oise

-in

ject

able

-can

.htm

l

AD

VER

SE R

EAC

TIO

NS

Prur

itis,

eryt

hem

a, p

yode

rma,

ocu

lar i

rrita

tion.

ht

tp://

ww

w.p

dr.n

et/se

arch

/sear

chR

esul

t.asp

x?se

arch

Crit

eria

=Ben

zyl+

alco

hol

12.

Bold

enon

e un

decy

lena

te

Equi

poise

inje

ctab

le

21 C

FR §

522

.204

-

“Do

not a

dmin

ister

to h

orse

s in

tend

ed fo

r hum

an c

onsu

mpt

ion.

” Eq

uipo

ise in

ject

able

(bol

deno

ne

unde

cyle

nate

inje

ctio

n) is

re

com

men

ded

as a

n ai

d fo

r tre

atin

g de

bilit

ated

hor

ses w

hen

an

impr

ovem

ent i

n w

eigh

t, ha

ircoa

t or

gene

ral p

hysic

al c

ondi

tion

is de

sired

. ht

tp://

ww

w.d

rugs

.com

/vet

/equ

ipoi

se-

inje

ctab

le-c

an.h

tml

Bol

deno

ne u

ndec

ylen

ate

is a

stero

id in

gred

ient

in E

quip

ose

(for h

orse

s).

It is

not

indi

cate

d fo

r use

in h

uman

s but

app

ears

to h

ave

off-l

abel

use

s as a

bod

ybui

ldin

g ste

roid

.K

now

n sid

e ef

fect

s con

sist o

f: n

ause

a, le

ukop

enia

, sym

ptom

s res

embl

ing

a pe

ptic

ul

cer,

acne

, exc

itatio

n (c

omm

only

refe

rred

to a

s roi

d ra

ge),

sleep

less

ness

, chi

lls,

vom

iting

, dia

rrhea

, hyp

erte

nsio

n, p

rolo

nged

blo

od c

lotti

ng ti

me,

incr

ease

in li

bido

. Fe

mal

es h

ad re

porte

d m

enstr

ual i

rregu

larit

ies,

post-

men

opau

sal b

leed

ing,

incr

ease

d se

x dr

ive,

swel

ling

of th

e br

easts

, hoa

rsen

ess o

r dee

peni

ng o

f the

voi

ce, a

nd

enla

rgem

ent o

f the

clit

oris.

Men

had

repo

rted

acne

, gyn

ocom

astia

, and

incr

ease

d ag

gres

sion.

ht

tp://

ww

w.a

nabo

licsm

all.c

om/e

quip

oise

.htm

lSt

eroi

ds sh

ould

be

take

n un

der a

doc

tor’s

supe

rvisi

on a

nd h

ave

mul

tiple

sign

ifica

nt

adve

rse

affe

cts i

nclu

ding

seve

re a

llerg

ic re

actio

ns, h

orm

onal

cha

nges

, cha

nges

in

men

strua

l fun

ctio

ns, m

enta

l and

moo

d ch

ange

s, re

spira

tory

pro

blem

s, na

usea

and

vo

miti

ng, j

oint

swel

ling,

visi

on c

hang

es, a

nd u

nusu

al w

eigh

t gai

n.

13.

Buto

rpha

nol

For t

he re

lief o

f pai

n as

soci

ated

with

co

lic a

nd p

ostp

artu

m p

ain

in a

dult

hors

es a

nd y

earli

ngs.

CO

MM

MO

N S

IDE

EFFE

CTS

D

izzi

ness

; dro

wsin

ess;

dry

mou

th; l

ight

-hea

dedn

ess;

nasa

l irri

tatio

n; n

ause

a; ru

nny

nose

; sor

e th

roat

; stu

ffy n

ose;

trou

ble

sleep

ing;

unp

leas

ant t

aste

; vom

iting

.

5

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

21 C

FR §

522

.246

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

SEV

ERE

SID

E EF

FEC

TS

Seve

re a

llerg

ic re

actio

ns (r

ash;

hiv

es; i

tchi

ng; d

iffic

ulty

bre

athi

ng; t

ight

ness

in th

e ch

est;

swel

ling

of th

e m

outh

, fac

e, li

ps, o

r ton

gue)

; blu

rred

visio

n; b

urni

ng, n

umbn

ess,

or ti

nglin

g; c

hang

e in

the

amou

nt o

f urin

e pr

oduc

ed; c

hest

pain

; con

fusio

n; e

ar p

ain;

fa

intin

g; fa

st, sl

ow, o

r irre

gula

r hea

rtbea

t; flu

shin

g; h

allu

cina

tions

; men

tal o

r moo

d ch

ange

s (ag

itatio

n, a

nxie

ty, d

epre

ssio

n); r

estle

ssne

ss; r

ingi

ng in

the

ears

; sei

zure

s; se

vere

or p

ersis

tent

diz

zine

ss, d

row

sines

s, or

ligh

t-hea

dedn

ess;

seve

re o

r per

siste

nt

head

ache

or t

roub

le sl

eepi

ng; s

hortn

ess o

f bre

ath;

slow

, sha

llow

, or d

iffic

ult

brea

thin

g; tr

emor

s; un

usua

l sw

ellin

g.

http

://w

ww

.dru

gs.c

om/sf

x/bu

torp

hano

l-sid

e-ef

fect

s.htm

l14

.Bu

toxy

Pol

ypro

pyle

ne

Gly

col

Farn

am B

ronc

o G

old

(fly

spra

y)

http

://m

sds.f

arna

m.c

om/m

0016

50.h

tm Fa

rnam

End

ure

Fly

Spra

y ht

tp://

msd

s.far

nam

.com

/m00

0080

.ht

m Farn

am E

ndur

e Sw

eat-R

esist

ant

http

://m

sds.f

arna

m.c

om/m

0010

46.h

tm Fa

rnam

Tri-

Tec

14

http

://m

sds.f

arna

m.c

om/m

0004

90.h

tm Fa

rnam

Wip

e (fl

y co

ntro

l

In 2

002,

a w

oman

in O

klah

oma

was

hos

pita

lized

afte

r usin

g Py

ranh

a fly

spra

y on

ho

rses

. Her

face

was

dist

orte

d, a

nd h

er w

ords

slur

red.

She

repo

rtedl

y ha

d le

g pr

oble

ms,

trem

ors,

mem

ory

prob

lem

s. Th

e m

edic

al to

xico

logi

st's c

oncl

usio

n w

as th

at

the

patie

nt, a

pro

fess

iona

l hor

se tr

aine

r, de

velo

ped

a co

mpl

ex n

euro

toxi

c m

ovem

ent

diso

rder

follo

win

g se

nsiti

zatio

n to

a p

rodu

ct th

at c

onta

ined

33%

/b

utox

ypol

ypro

pyle

ne g

lyco

l/ B

PG.

Adv

erse

reac

tions

and

side

effe

cts o

f ing

estio

n ar

e un

know

n.

15.

Car

bado

x A

ntib

iotic

use

d fo

r gro

wth

pro

mot

ion

purp

oses

(gen

eric

) N

ot p

erm

itted

for u

se in

food

-pro

duci

ng a

nim

als i

n A

ustra

lia

(http

://w

ww

.apv

ma.

gov.

au/re

gistr

atio

n/no

t_pe

rmitt

ed.p

hp)

Or i

n C

anad

a, o

r the

Eur

opea

n U

nion

. (ht

tp://

ww

w.h

c-sc

.gc.

ca/d

hp-

mps

/vet

/faq/

faq_

mrl-

lmr-e

ng.p

hp#a

6)N

ot fo

r hum

an u

se.

http

://w

ww

.dru

gs.c

om/p

ro/m

ecad

ox.h

tml

Chr

onic

hea

lth e

ffect

s, in

clud

ing

canc

er, m

utag

enic

effe

ct, c

hang

es in

lung

func

tion.

A

ccid

enta

l ing

estio

n m

ay c

ause

serio

us h

arm

or b

e fa

tal.

MSD

S SU

PPLI

ER

http

://da

tash

eets.

scbt

.com

/sc-2

0466

8.pd

f16

.C

eftio

fur

Cry

stal

line

Free

A

cid

Exce

de (a

ntib

iotic

) Fo

r the

trea

tmen

t of l

ower

resp

irato

ry

tract

infe

ctio

ns in

hor

ses.

21 C

FR §

522

.313

a

Inte

nded

for u

se in

hor

ses w

hich

are

non

-food

ani

mal

s. B

ecau

se th

is in

dica

tion

for

this

new

ani

mal

dru

g is

not i

nten

ded

for u

se in

food

pro

duci

ng a

nim

als,

ther

e is

no

data

per

tain

ing

to d

rug

resid

ues i

n fo

od (i

.e.,

hum

an fo

od sa

fety

). W

AR

NIN

GS

6

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” ht

tp://

ww

w.e

xced

e.co

m/E

xced

e.as

px?c

ount

ry=U

S&dr

ug=X

T&se

c=10

0&sp

ecie

s=EQ

Not

for u

se in

hum

ans.

For

use

in a

nim

als o

nly.

Con

sult

a ph

ysic

ian

in c

ase

of

acci

dent

al h

uman

exp

osur

e.

Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.

http

://an

imal

heal

th.p

fizer

.com

/site

s/pah

web

/US/

EN/P

rodu

cts/D

ocum

ents/

Com

bine

d%

20Fu

ll%20

PI%

20(8

_5x1

1)%

20-%

20EX

EQ01

1001

4.pd

f

17.

Cef

tiofu

r So

dium

C

eftif

lex

pow

der

For t

reat

men

t of r

espi

rato

ry

infe

ctio

ns in

hor

ses.

21 C

FR §

522

.313

c -

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

http

://w

ww

.dru

gs.c

om/v

et/c

eftif

lex.

htm

l

Peni

cilli

ns a

nd c

epha

losp

orin

s can

cau

se a

llerg

ic re

actio

ns in

sens

itize

d in

divi

dual

s.

Topi

cal e

xpos

ure

to su

ch a

ntim

icro

bial

s, in

clud

ing

cefti

ofur

, may

elic

it m

ild to

seve

re

alle

rgic

reac

tions

in so

me

indi

vidu

als.

Rep

eate

d or

pro

long

ed e

xpos

ure

may

lead

to

sens

itiza

tion.

Avo

id d

irect

con

tact

of t

he p

rodu

ct w

ith th

e sk

in, e

yes,

mou

th, a

nd

clot

hing

. ht

tp://

ww

w.d

rugs

.com

/vet

/cef

tifle

x.ht

ml

18.

Chl

oram

phen

icol

C

hlor

-500

C

hlor

-100

0Ch

lora

mph

enic

ol 1

% O

intm

ent

“Not

for u

se in

ani

mal

s tha

t are

ra

ised

for f

ood

prod

uctio

n. M

ust n

ot

be u

sed

in m

eat,

egg,

or m

ilk-

prod

ucin

g an

imal

s. 21

CFR

§ 5

20.3

90a;

520

.390

c;

522.

390;

524

.390

. ht

tp://

ww

w.d

rugs

.com

/vet

/chl

or-5

00-

can.

htm

lht

tp://

ww

w.d

rugs

.com

/vet

/chl

or-

1000

-can

.htm

lht

tp://

ww

w.d

rugs

.com

/cdi

/chl

oram

phen

icol

.htm

lht

tp://

ww

w.d

rugs

.com

/vet

/chl

oram

phen

icol

-1-o

phth

alm

ic-o

intm

ent-

can.

htm

l

Som

e m

edic

ines

may

inte

ract

with

Chl

oram

phen

icol

: •A

ntic

oagu

lant

s (e.

g., w

arfa

rin) b

ecau

se si

de e

ffect

s, in

clud

ing

risk

of b

leed

ing,

may

be

incr

ease

d.

•Hyd

anto

ins (

e.g.

, phe

nyto

in) o

r sul

fony

lure

as (e

.g.,

glyb

urid

e) b

ecau

se th

e ac

tions

an

d sid

e ef

fect

s of t

hese

med

icin

es m

ay b

e in

crea

sed.

•M

edic

ines

that

may

dec

reas

e yo

ur b

one

mar

row

(e.g

., ca

ncer

che

mot

hera

py) b

ecau

se

the

risk

of se

rious

side

effe

cts,

such

as l

ow b

lood

pla

tele

t lev

els a

nd lo

w w

hite

blo

od

cell

coun

ts, m

ay b

e in

crea

sed.

C

hlor

amph

enic

ol h

as c

ause

d se

vere

and

som

etim

es fa

tal b

lood

pro

blem

s (e.

g.,

anem

ia, l

ow b

lood

pla

tele

ts, lo

w w

hite

blo

od c

ell c

ount

s).

Leuk

emia

has

also

bee

n re

porte

d af

ter u

se o

f Chl

oram

phen

icol

. B

lood

pro

blem

s hav

e oc

curre

d af

ter b

oth

shor

t-ter

m a

nd lo

ng-te

rm u

se o

f Chl

oram

phen

icol

. D

o no

t use

chl

oram

phen

icol

if

safe

r, ef

fect

ive

med

icin

es c

an b

e us

ed.

http

://w

ww

.dru

gs.c

om/c

di/c

hlor

amph

enic

ol.h

tml

Proh

ibite

d fo

r use

in fo

od-p

rodu

cing

ani

mal

s in

the

Euro

pean

Uni

on.

19.

Chl

orof

orm

A

nesth

etic

Th

e IA

RC

(Int

erna

tiona

l Age

ncy

for R

esea

rch

on C

ance

r) cl

assif

ies c

hlor

ofor

m a

s po

ssib

ly c

arci

noge

nic

to h

uman

s. ht

tp://

mon

ogra

phs.i

arc.

fr/EN

G/M

onog

raph

s/vol

73/m

ono7

3.pd

f20

.C

imet

idin

e Pr

even

tion

and

prop

hyla

xis o

f A

DV

ERSE

REA

CTI

ON

S

7

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

gastr

oint

estin

al ir

ritat

ion

and

ulce

rs

Dia

rrhea

, hea

dach

e, d

izzi

ness

, som

nole

nce,

reve

rsib

le c

onfu

siona

l sta

tes,

reve

rsib

le

impo

tenc

e, in

crea

sed

seru

m tr

ansa

min

ases

, ras

h, g

ynec

omas

tia, b

lood

dys

cras

ias.

WA

RN

ING

S/PR

ECA

UTI

ON

SR

ever

sible

con

fusio

nal s

tate

s rep

orte

d, e

spec

ially

in se

vere

ly il

l pat

ient

s. In

crea

sed

risk

of d

evel

opin

g co

nfus

iona

l sta

tes w

ith a

dvan

cing

age

(50

yrs

), re

nal a

nd/o

r he

patic

impa

irmen

t. R

isk o

f hyp

erin

fect

ion

of st

rong

yloi

dias

is in

im

mun

ocom

prom

ised

patie

nts.

http

://w

ww

.pdr

.net

/dru

gpag

es/c

onci

sem

onog

raph

.asp

x?co

ncise

=144

021

.C

lenb

uter

ol

Bet

a-ag

onist

s use

d fo

r gro

wth

pr

omot

ion

purp

oses

Pr

ohib

ited

from

any

use

in a

ny fo

od-

prod

ucin

g an

imal

. ht

tp://

ww

w.fa

rad.

org/

eldu

/pro

hibi

t.as

p

Not

app

rove

d fo

r hum

an u

se.

http

://w

ww

.dea

dive

rsio

n.us

doj.g

ov/d

rugs

_con

cern

/cle

nbut

erol

.htm

22.

Cop

per

Nap

hthe

nate

K

oper

tox

Trea

tmen

t of t

hrus

h.

21 C

FR §

524

.463

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

http

://w

ww

.dru

gs.c

om/v

et/k

oper

tox.

htm

lht

tp://

ww

w.sc

ienc

elab

.com

/msd

s.php

?msd

sId=

9923

553

Toxi

c to

cen

tral n

ervo

us sy

stem

, blo

od, a

nd k

idne

ys.

May

pro

duce

vom

iting

, hea

dach

e, sh

ock,

jaun

dice

, kid

ney

dam

age,

ner

vous

syste

m

dam

age,

live

r dam

age.

23.

Cru

de L

iver

Ext

ract

Li

ver 7

inje

ctio

n ht

tp://

ww

w.d

rugs

.com

/vet

/live

r-7-

inje

ctio

n.ht

ml

FDA

cau

tions

aga

inst

the

use

by h

uman

s of a

ny a

nim

al o

rgan

ext

ract

. ht

tp://

ww

w.h

ealth

line.

com

/nat

stand

ardc

onte

nt/li

ver-e

xtra

ct

24.

Cup

ric

Sulfa

te

Prou

dsof

f (oi

ntm

ent f

or c

ontro

l and

re

mov

al o

f pro

ud fl

esh)

N

ot fo

r use

on

anim

als i

nten

ded

for

food

.ht

tp://

ww

w.d

rugs

.com

/vet

/pro

udso

ff.ht

ml

Har

mfu

l if s

wal

low

ed.

May

cau

se g

astro

inte

stina

l tra

ct ir

ritat

ion

with

nau

sea,

vo

miti

ng, d

iarrh

ea, m

etal

lic ta

ste, b

urni

ng se

nsat

ion

in th

e sto

mac

h or

epi

gastr

um,

abdo

min

al p

ain,

and

pos

sible

gas

troin

testi

nal t

ract

ble

edin

g. M

ay a

ffect

met

abol

ism,

liver

(liv

er d

amag

e, ja

undi

ce),

bloo

d, u

rinar

y sy

stem

(kid

ney

dam

age,

hem

atur

ia,

hem

oglo

binu

ria, a

lbum

inur

ia),

beha

vior

/ner

vous

syste

ms (

som

nole

nce,

trem

or,

psyc

hosis

, mus

cle

wea

knes

s, co

ma)

, car

diov

ascu

lar s

yste

m (l

ower

ing

of b

lood

pr

essu

re, d

ysrh

ythm

ia).

25.

Cyp

erm

ethr

in

Farn

am E

ndur

e Sw

eat-R

esist

ant (

fly

spra

y ht

tp://

msd

s.far

nam

.com

/m00

0080

.ht

“Pyr

ethr

oid

inge

stion

giv

es ri

se w

ithin

min

utes

to a

sore

thro

at, n

ause

a, v

omiti

ng a

nd

abdo

min

al p

ain.

The

re m

ay b

e m

outh

ulc

erat

ion,

incr

ease

d se

cret

ions

and

/or

dysp

hagi

a. S

yste

mic

effe

cts o

ccur

4-4

8 ho

urs a

fter e

xpos

ure.

Diz

zine

ss, h

eada

che

and

fatig

ue a

re c

omm

on, a

nd p

alpi

tatio

ns, c

hest

tight

ness

and

blu

rred

visio

n le

ss

8

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

m

frequ

ent.

Com

a an

d co

nvul

sions

are

the

prin

cipa

l life

-thre

aten

ing

feat

ures

. Mos

t pa

tient

s rec

over

with

in 6

day

s. . .

.”

S.M

. Bra

dber

ry e

t al.,

Poiso

ning

Due

to

Pyre

thro

ids,

Toxi

col R

ev. 2

4(2)

:93-

106

(200

5) (q

uotin

g ab

strac

t).

Pote

ntia

l org

an d

amag

e.

http

://pm

ep.c

ce.c

orne

ll.ed

u/pr

ofile

s/ext

oxne

t/car

bary

l-dic

roto

phos

/cyp

erm

et-e

xt.h

tml

26.

Dap

sone

D

erm

atiti

s ski

n pr

oble

ms i

n ho

rses

. A

cne

treat

men

t in

hum

ans.

Adv

erse

effe

cts i

nclu

de a

gran

uloc

ytos

is, a

plas

tic a

nem

ia, l

euco

peni

a,

thro

mbo

cyto

peni

a, h

emol

ysis,

and

oth

er b

lood

dys

cras

ias h

ave

been

repo

rted

afte

r tre

atm

ent.

It m

ay c

ause

sign

ifica

nt re

duct

ion

in le

ukoc

ytes

, pla

tele

ts, o

r hem

opoi

esis.

C

autio

n w

ith g

luco

se-6

-pho

spho

ate

dehy

drog

enas

e (G

6PD

) def

icie

ncy,

m

ethe

mog

lobi

n re

duct

ase

defic

ienc

y, o

r hem

oglo

bin

M, a

nd th

ose

who

are

exp

osed

to

othe

r age

nts o

r con

ditio

ns su

ch a

s inf

ectio

n or

dia

betic

ket

osis

capa

ble

of p

rodu

cing

he

mol

ysis.

Tox

ic h

epat

itis a

nd c

hole

static

jaun

dice

repo

rted

afte

r use

. Li

ver f

unct

ion

tests

mus

t be

mon

itore

d if

ther

e ar

e an

y ab

norm

aliti

es.

Can

cau

se m

uscl

e w

eakn

ess.

Perip

hera

l neu

ropa

thy,

nau

sea

and

vom

iting

, abd

omin

al p

ain,

and

pan

crea

titis

may

oc

cur.

http

://w

ww

.pdr

.net

/sear

ch/se

arch

Res

ult.a

spx?

sear

chC

riter

ia=D

apso

ne27

.D

eodo

rize

d K

eros

ene

Com

pone

nt in

Far

nam

Rep

el X

p (fl

y sp

ray)

. ht

tp://

msd

s.far

nam

.com

/m00

0031

.ht

m

Inge

stion

may

cau

se a

spira

tion

haza

rd, n

ause

a, fa

tigue

, pul

mon

ary

edem

a, c

entra

l ne

rvou

s sys

tem

epre

ssio

n, c

onvu

lsion

s and

loss

of c

onsc

ious

ness

. ht

tp://

ww

w.sc

ienc

estu

ff.co

m/m

sds/C

1955

.htm

l

28.

Des

lore

lin

Use

d fo

r ind

ucin

g ov

ulat

ion

with

in

48 h

ours

in o

vula

ting

mar

es.

21 C

FR §

522

.533

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

Des

lore

lin st

ops t

he p

rodu

ctio

n of

cer

tain

sex

horm

ones

in h

orse

s, an

d ha

s nev

er b

een

appr

oved

for u

se o

n hu

man

s. If

it w

as a

ppro

ved,

it w

ould

be

for a

smal

l tar

gete

d co

mpl

emen

t of t

he h

uman

pop

ulat

ion

with

iden

tifie

d di

seas

es re

late

d to

the

prod

uctio

n of

too

muc

h of

cer

tain

sex

horm

ones

, but

cou

ld o

ther

wise

pro

duce

un

wan

ted

horm

onal

effe

cts a

nd re

spon

ses.

29.

Det

omid

ine

Hyd

roch

lori

deD

orm

osed

an

Pain

relie

f and

seda

tive

for m

inor

su

rger

y. A

lso u

sed

in h

uman

s for

se

datio

n in

inte

nsiv

e ca

re a

nd su

rger

y co

nditi

ons.

21 C

FR §

522

.536

; 529

.536

-

Not

for u

se in

hor

ses i

nten

ded

for

food

.”-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

http

://w

ww

.dor

mos

edan

.com

/

Can

cau

se h

ypot

ensio

n, h

yper

tens

ion,

bra

dyca

rdia

, dry

mou

th, r

espi

rato

ry d

epre

ssio

n,

tach

ycar

dia,

nau

sea

and

vom

iting

, atri

al fi

brill

atio

n, fe

ver,

hype

rgly

cem

ia, a

nem

ia,

hypo

vole

mia

, hyp

oxia

, ate

lect

asis.

ht

tp://

ww

w.p

dr.n

et/d

rugp

ages

/con

cise

mon

ogra

ph.a

spx?

conc

ise=2

848

9

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

30.

Dex

amet

haso

ne

Dex

ium

inje

ctio

n A

nti-i

nfla

mm

ator

y dr

ug.

21 C

FR §

522

.540

-

(d)(4

) (ste

rile

aque

ous s

olut

ion)

. “N

ot fo

r use

in h

orse

s int

ende

d fo

r fo

od.”

- (e

)(5) (

steril

e aq

ueou

s sol

utio

n).

“Not

for u

se in

hor

ses i

nten

ded

for

food

.”21

CFR

§ 5

22.5

42

- “N

ot fo

r use

in h

orse

s int

ende

d fo

r foo

d.”

http

://w

ww

.dru

gs.c

om/v

et/d

exiu

m-

inje

ctio

n.ht

ml

Ster

oid

for h

uman

s.

Adv

erse

reac

tions

incl

ude

fluid

/ele

ctro

lyte

dist

urba

nces

, mus

cle

wea

knes

s, os

teop

oros

is, p

eptic

ulc

er, p

ancr

eatit

is, u

lcer

ativ

e es

opha

gitis

, im

paire

d w

ound

he

alin

g, h

eada

che,

psy

chic

dist

urba

nces

, gro

wth

supp

ress

ion

(ped

iatri

cs),

glau

com

a,

hype

rgly

cem

ia, w

eigh

t gai

n, n

ause

a, m

alai

se.

http

://w

ww

.pdr

.net

/dru

gpag

es/c

onci

sem

onog

raph

.asp

x?co

ncise

=798

Ster

oids

shou

ld b

e ta

ken

unde

r a d

octo

r’s su

perv

ision

and

hav

e m

ultip

le si

gnifi

cant

ad

vers

e af

fect

s inc

ludi

ng se

vere

alle

rgic

reac

tions

, hor

mon

al c

hang

es, c

hang

es in

m

enstr

ual f

unct

ions

, men

tal a

nd m

ood

chan

ges,

resp

irato

ry p

robl

ems,

naus

ea a

nd

vom

iting

, joi

nt sw

ellin

g, v

ision

cha

nges

, and

unu

sual

wei

ght g

ain.

31.

Dic

hlor

omet

hane

Fu

rall

Ant

ibac

teria

l ht

tp://

msd

s.far

nam

.com

/m00

0394

.ht

m

If ea

ten,

this

drug

can

cau

se g

astro

inte

stina

l irri

tatio

n w

ith n

ause

a, v

omiti

ng a

nd

diar

rhea

. M

ay c

ause

kid

ney

dam

age.

May

cau

se c

entra

l ner

vous

syste

m d

epre

ssio

n,

char

acte

rized

by

exci

tem

ent,

follo

wed

by

head

ache

, diz

zine

ss, d

row

sines

s, an

d na

usea

. A

dvan

ced

stage

s may

cau

se c

olla

pse,

unc

onsc

ious

ness

, com

a an

d po

ssib

le

deat

h du

e to

resp

irato

ry fa

ilure

. M

ay c

ause

car

boxy

hem

oglo

bine

mia

. D

ichl

orom

etha

ne h

as b

een

treat

ed a

s a c

arci

noge

n in

Cal

iforn

ia si

nce

1988

and

it m

ay

also

hav

e ad

vers

e re

prod

uctiv

e ef

fect

s. ht

tp://

ww

w.sc

ienc

elab

.com

/msd

s.php

?msd

sId=

9948

&co

de=S

LM26

7732

.D

icla

zuri

l C

linac

ox A

ntip

roto

zoal

U

sed

to tr

eat i

nfec

tions

lead

ing

to

myo

ence

phal

itis.

21 C

FR §

520

.606

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

Adm

inist

ered

to so

me

AID

S pa

tient

s, bu

t effe

cts i

n hu

man

s lar

gely

unk

now

n.

33.

Dic

lofe

nac

Sodi

um

Surp

ass (

topi

cal)

Arth

ritis

treat

men

t in

hum

ans a

nd

hors

es.

21 C

FR §

524

.590

-

“Do

not u

se fo

r hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

http

://w

ww

.dru

gs.c

om/v

et/su

rpas

s-

May

cau

se h

yper

tens

ion,

ede

ma,

or h

eart

failu

re.

Som

e in

divi

dual

s with

prio

r ga

stroi

ntes

tinal

dise

ase

may

be

hype

rsen

sitiv

e to

the

drug

’s e

ffect

s. P

oten

tial k

idne

y fa

ilure

and

dan

ger f

or p

atie

nts w

ith re

nal d

iseas

e. M

ay c

ause

ana

phyl

actic

reac

tions

; m

ay h

arm

fetu

s in

uter

o. M

ayca

use

liver

pro

blem

s. M

ay c

ause

ane

mia

and

affe

ct

bloo

d. M

ay c

ause

abd

omin

al p

ain,

con

stipa

tion,

dia

rrhea

, dys

peps

ia, f

latu

lenc

e, g

ross

bl

eedi

ng/p

erfo

ratio

n, h

eartb

urn,

nau

sea

and

vom

iting

, gas

troin

testi

nal u

lcer

s, re

nal

func

tion

abno

rmal

ities

, ane

mia

, diz

zine

ss, e

dem

a, e

leva

ted

liver

enz

ymes

. ht

tp://

ww

w.p

dr.n

et/se

arch

/sear

chR

esul

t.asp

x?se

arch

Crit

eria

=Dic

lofe

nac+

Sodi

um

10

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

topi

cal-c

ream

.htm

l34

.D

iflub

enzu

ron

Equi

trol I

I Fl

y co

ntro

l ht

tp://

ww

w.d

rugs

.com

/vet

/equ

itrol

-ii-

feed

-thru

-fly-

cont

rol.h

tml

May

cau

se a

nem

ia.

35.

Dim

ethy

lsulfo

xide

To

pica

l app

licat

ion

for s

prai

ns,

sore

ness

; may

also

be

inje

cted

or

com

bine

d w

ith o

ther

dru

gs fo

r ad

min

istra

tion.

Li

mite

d tre

atm

ent u

se in

hum

ans -

- us

ed a

s a to

pica

l app

licat

ion

to

redu

ce a

cute

swel

ling

due

to tr

aum

a.

21 C

FR §

524

.660

a -

Dim

ethy

l sul

foxi

de so

lutio

n -

“Not

for u

se in

hor

ses a

nd d

ogs

inte

nded

for b

reed

ing

purp

oses

nor

in

hors

es sl

augh

tere

d fo

r foo

d.”

21 C

FR §

524

.660

b -

Dim

ethy

l sul

foxi

de g

el

- “D

o no

t use

in h

orse

s and

dog

s in

tend

ed fo

r bre

edin

g pu

rpos

es o

r in

hors

es sl

augh

tere

d fo

r foo

d.”

http

://w

ww

.web

md.

com

/vita

min

s-su

pple

men

ts/in

gred

ient

mon

o-87

4-D

MSO

%20

(DIM

ETH

YLS

ULF

OX

ID

E).a

spx?

activ

eIng

redi

entId

=874

&a

ctiv

eIng

redi

entN

ame=

DM

SO%

20(D

IMET

HY

LSU

LFO

XID

E)

May

cau

se h

eada

che,

diz

zine

ss, d

row

sines

s, na

usea

, vom

iting

, dia

rrhea

, con

stipa

tion,

br

eath

ing

prob

lem

s, vi

sion

prob

lem

s, bl

ood

prob

lem

s, an

d al

lerg

ic re

actio

ns.

Also

m

ay h

arm

the

liver

and

kid

neys

. ht

tp://

ww

w.w

ebm

d.co

m/v

itam

ins-

supp

lem

ents/

ingr

edie

ntm

ono-

874-

DM

SO%

20(D

IMET

HY

LSU

LFO

XID

E).a

spx?

activ

eIng

redi

entId

=874

&ac

tiveI

ngre

dien

tNam

e=D

MSO

%20

(DIM

ETH

YLS

ULF

OX

IDE)

MSD

S av

aila

ble

here

: ht

tp://

ww

w.sc

ienc

elab

.com

/msd

s.php

?msd

sId=

9927

347

36.

Dim

etri

dazo

le (g

ener

ic)

Bac

teric

idal

A

ntib

acte

rial

With

draw

n fro

m E

urop

ean

mar

ket b

ecau

se o

f dan

gers

of g

astro

inte

stina

l pro

blem

s, po

tent

ial f

or c

ance

r. ht

tp://

ww

w.b

ioag

rimix

.com

/msd

s/36/

3628

0/36

2800

7.pd

f

37.

Di-n

-pro

pyl

isoci

ncho

mer

onat

e Fl

y co

ntro

l pro

duct

s: H

igh

toxi

city

– c

lass

ified

as a

car

cino

geni

c Pe

stic

ide

Act

ion

Net

wor

k (P

AN

) “B

ad

Act

or”.

1

1 “PA

N B

ad A

ctor

pes

ticid

es”

belo

ng to

a “

mos

t tox

ic”

set o

f pes

ticid

es id

entif

ied

by th

e Pe

stic

ide

Act

ion

Net

wor

k an

d C

alifo

rnia

ns fo

r Pes

ticid

e R

efor

m (C

PR).

Th

ese

pest

icid

es a

re a

t lea

st o

ne o

f the

follo

win

g: k

now

n or

pro

babl

e ca

rcin

ogen

s, as

des

igna

ted

by th

e In

tern

atio

nal A

genc

y fo

r Res

earc

h on

Can

cer (

IAR

C),

U.S

. EP

A, U

.S. N

atio

nal T

oxic

olog

y Pr

ogra

m, a

nd th

e st

ate

of C

alifo

rnia

’s P

ropo

sitio

n 65

list

; rep

rodu

ctiv

e or

dev

elop

men

tal t

oxic

ants

, as d

esig

nate

d by

the

stat

e of

11

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

Flys

ect S

uper

-7 re

pelle

nt sp

ray

Flys

ect S

uper

-C

Mos

quito

Hal

t ht

tp://

ww

w.d

rugs

.com

/vet

/flys

ect-

supe

r-7.h

tml

http

://m

sds.f

arna

m.c

om/m

0008

11.h

tm ht

tp://

ww

w.d

rugs

.com

/vet

/flys

ect-

supe

r-c.h

tml

http

://w

ww

.dru

gs.c

om/v

et/m

osqu

ito-

halt-

repe

llent

-spr

ay-fo

r-hor

ses.h

tml

ww

w.p

estic

idei

nfo.

org/

Det

ail_

Che

mic

al.js

p?R

ec_i

d=PC

2798

38.

Dip

ropy

l iso

cinc

hom

eron

ate

Farn

am R

oll-O

n Re

pelle

nt (f

ly sp

ray)

ht

tp://

msd

s.far

nam

.com

/m00

0018

.ht

m

Hig

h to

xici

ty –

PA

N B

ad A

ctor

. C

arci

noge

nic.

w

ww

.pes

ticid

einf

o.or

g/D

etai

l_C

hem

ical

.jsp?

Rec

_id=

PC27

9839

.D

ompe

rido

ne

In h

orse

s, us

ed fo

r tre

atm

ent o

f to

xici

ty fr

om fe

scue

gra

ss th

at a

ffect

s pr

egna

ncie

s. In

hum

ans,

used

to in

crea

se b

owel

co

ntra

ctio

ns a

nd c

omba

t nau

sea

and

vom

iting

cau

sed

by o

ther

dru

gs.

21 C

FR §

520

.766

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

http

://w

ww

.fda.

gov/

Ani

mal

Vet

erin

ary/

Safe

tyH

ealth

/Pro

duct

Safe

tyIn

form

atio

n/uc

m23

5691

.htm

FDA

has

war

ned

that

this

drug

pas

ses i

nto

brea

st m

ilk a

nd sh

ould

not

be

used

in

nurs

ing

hum

an m

othe

rs.

Side

effe

cts i

nclu

de d

izzi

ness

, dry

mou

th, n

ervo

usne

ss, f

lush

ing,

irrit

abili

ty, i

nsom

nia,

sto

mac

h cr

amps

, hot

flas

hes a

nd le

g cr

amps

, che

st pa

in, s

low

/fast/

irreg

ular

hea

rtbea

t, sw

ellin

g of

the

feet

or a

nkle

s, di

fficu

lty u

rinat

ing,

swel

ling

of th

e br

easts

or d

ischa

rge

from

the

nipp

le in

men

or w

omen

, men

strua

l cha

nges

, sex

ual d

iffic

ultie

s. M

ay a

ffect

abs

orpt

ion

and

actio

n of

oth

er d

rugs

, and

inte

ract

with

oth

er d

rugs

. ht

tp://

ww

w.m

edic

inen

et.c

om/d

ompe

ridon

e-or

al/a

rticl

e.ht

m

40.

Dox

ycyc

line

A

ntib

iotic

for h

orse

s and

hum

ans.

http

://w

ww

.dru

gs.c

om/c

di/d

oxyc

ycli

ne-c

apsu

les.h

tml

Dan

gero

us fo

r pre

gnan

t wom

en; m

ay c

ause

toot

h pr

oble

ms,

gastr

oint

estin

al

sym

ptom

s, au

toim

mun

e sy

ndro

me,

rena

l pro

blem

s.

Cal

iforn

ia’s

Pro

posi

tion

65 li

st; n

euro

toxi

c ch

olin

este

rase

inhi

bito

rs, a

s des

igna

ted

by C

alifo

rnia

Dep

artm

ent o

f Pes

ticid

e R

egul

atio

n, th

e M

ater

ials

Saf

ety

Dat

a Sh

eet f

or th

e pa

rticu

lar c

hem

ical

, or P

AN

staf

f eva

luat

ion

of c

hem

ical

stru

ctur

e (f

or o

rgan

opho

spho

rus c

ompo

unds

); kn

own

grou

ndw

ater

con

tam

inan

ts, a

s de

sign

ated

by

the

stat

e of

Cal

iforn

ia (f

or a

ctiv

ely

regi

ster

ed p

estic

ides

) or f

rom

his

toric

gro

undw

ater

mon

itorin

g re

cord

s (fo

r ban

ned

pest

icid

es);

pest

icid

es w

ith

high

acu

te to

xici

ty, a

s des

igna

ted

by th

e W

orld

Hea

lth O

rgan

izat

ion

(WH

O),

the

U.S

. EPA

, or t

he U

.S. N

atio

nal T

oxic

olog

y Pr

ogra

m.

12

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

41.

Dox

ylam

ine

succ

inat

e A

ntih

istam

ine

Ant

icho

linar

gic

21 C

FR 5

20.7

84

- “N

ot fo

r use

in h

orse

s int

ende

d fo

r foo

d.”

Not

to b

e co

mbi

ned

with

oth

er a

ntih

istam

ines

. C

an c

ause

mul

tiple

adv

erse

side

ef

fect

s.

42.

Equi

ne In

fluen

za v

acci

ne

Kill

ed v

irus v

acci

ne

Not

inte

nded

for h

uman

use

and

no

testi

ng o

n hu

man

inge

stion

of t

his v

acci

ne.

43.

Equi

ne R

hino

pneu

mon

itis

– In

fluen

za v

acci

ne

Kill

ed v

irus v

acci

ne

Pres

tige

II w

ith H

avlo

gen

(vac

cine

) ht

tp://

inte

rvet

us.n

accv

p.co

m/?

m=p

rodu

ct_v

iew

&id

=104

7348

Not

inte

nded

for h

uman

use

and

no

testi

ng o

n hu

man

inge

stion

of t

his v

acci

ne.

44.

Estr

adio

l Fe

mal

e ho

rmon

e fo

r man

agem

ent o

f re

prod

uctiv

e fu

nctio

ns in

hor

ses,

and

for r

elie

f of m

enop

ausa

l sym

ptom

s in

hum

ans

Estra

diol

Cyp

iona

te in

Oil

Estra

diol

ena

ntha

te; E

strad

iol

benz

oate

Risk

of c

ance

r is a

mon

g th

e m

ultip

le p

oten

tial n

egat

ive

side

effe

cts r

elat

ed to

the

un

appr

oved

and

unc

ontro

lled

use

of th

is sy

nthe

tic fe

mal

e ho

rmon

e. O

ther

side

effe

cts

incl

ude

head

ache

s, di

zzin

ess,

brea

st pa

in, i

ncre

ased

risk

for y

east

infe

ctio

ns, f

lu-li

ke

sym

ptom

s, ar

thrit

ic p

ain,

hai

r los

s, ga

stroi

ntes

tinal

pro

blem

s inc

ludi

ng n

ause

a or

vo

miti

ng, a

nd in

cide

nces

of s

potti

ng in

bet

wee

n pe

riods

or o

ther

men

strua

l irr

egul

ariti

es.

May

be

unsa

fe fo

r peo

ple

with

blo

od d

isord

ers,

hear

t dise

ase,

obe

sity,

seiz

ure

diso

rder

s or c

erta

in a

llerg

ies.

45.

Euca

lypt

us O

il Sc

arle

t Oil

Wou

nd D

ress

ing

http

://w

ww

.dru

gs.c

om/v

et/sc

arle

t-oi

l.htm

lLa

bele

d “N

ot fo

r use

on

anim

als

inte

nded

for f

ood.

Pote

ntia

l sid

e ef

fect

s inc

lude

seiz

ures

, poi

soni

ng, d

row

sines

s, m

orbi

dity

in c

hild

ren,

ce

ntra

l ner

vous

syste

m, d

epre

ssio

n.

46.

Fenb

enda

zole

D

ewor

mer

(Pan

acur

) Eq

ui-b

itsPa

nacu

r Pas

te

Pana

cur P

ower

Pac

Pa

nacu

r Sus

pens

ion

Safe

-Gua

rd

Safe

-Gua

rd P

ower

-Dos

e 21

CFR

§ 5

20.9

05a

- “D

o no

t use

in h

orse

s int

ende

d

No

hum

an fo

rmul

atio

n, a

nd a

dver

se e

ffect

s on

hum

ans w

ho e

at th

is de

wor

mer

, tha

t di

rect

ly a

ffect

s the

gas

troin

testi

nal t

ract

, are

unk

now

n.

13

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

for h

uman

con

sum

ptio

n.”

47.

Firo

coxi

b Eq

uiox

x N

on-s

tero

idal

ant

i-inf

lam

mat

ory

drug

(NSA

ID).

21 C

FR §

520

.930

; 522

.930

-

Firo

coxi

b pa

ste.

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” ht

tp://

ww

w.e

quio

xx.c

om/

Ther

e is

no a

ppro

ved

use

of th

is dr

ug fo

r hum

ans a

nd so

any

adv

erse

effe

cts o

n hu

man

s who

inge

st th

is dr

ug a

re c

ompl

etel

y un

know

n.

Firo

coxi

b is

one

of th

e N

SAID

s, al

l of w

hich

hav

e ex

tens

ive

pote

ntia

l adv

erse

side

ef

fect

s in

hum

ans i

nclu

ding

car

diov

ascu

lar,

gastr

oint

estin

al, k

idne

y an

d ey

e pr

oble

ms.

Th

e N

SAID

s can

be

dang

erou

s for

indi

vidu

als w

ith b

lood

diso

rder

s. T

hey

are

also

co

ntra

indi

cate

d du

ring

preg

nanc

y. T

hey

also

pre

sent

sign

ifica

nt ri

sk fo

r peo

ple

with

a

histo

ry o

f ulc

ers o

r gas

troin

testi

nal b

leed

ing.

Can

cau

se n

ause

a, a

bdom

inal

pai

n,

diar

rhea

, hea

dach

es, e

xcita

bilit

y, a

nd n

ervo

us sy

stem

pro

blem

s.

48.

Flun

ixin

N

SAID

:Ba

nam

ine

(sol

utio

n or

pas

te) (

pain

ki

ller)

Flun

azin

e in

ject

able

Fl

u-ni

x D

inje

ctio

n Fl

unix

amin

e 21

CFR

§ 5

20.9

70

- G

ranu

les

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” 21

CFR

§ 5

22.9

70

- In

ject

ible

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

Flun

ixin

is o

ne o

f the

NSA

IDs,

all o

f whi

ch h

ave

exte

nsiv

e po

tent

ial a

dver

se si

de

effe

cts i

n hu

man

s inc

ludi

ng c

ardi

ovas

cula

r, ga

stroi

ntes

tinal

, kid

ney

and

eye

prob

lem

s.

The

NSA

IDs c

an b

e da

nger

ous f

or in

divi

dual

s with

blo

od d

isord

ers.

The

y ar

e al

so

cont

rain

dica

ted

durin

g pr

egna

ncy.

The

y al

so p

rese

nt si

gnifi

cant

risk

for p

eopl

e w

ith a

hi

story

of u

lcer

s or g

astro

inte

stina

l ble

edin

g. C

an c

ause

nau

sea,

abd

omin

al p

ain,

di

arrh

ea, h

eada

ches

, exc

itabi

lity,

and

ner

vous

syste

m p

robl

ems.

49.

Flun

ixin

Meg

lum

ine

NSA

ID:

Flun

azin

e in

ject

able

Fl

u-ni

x D

inje

ctio

n Fl

unix

amin

e La

bele

d: N

ot fo

r use

in h

orse

s in

tend

ed fo

r foo

d.

http

://w

ww

.dru

gs.c

om/v

et/fl

unix

in-

meg

lum

ine-

inje

ctio

n.ht

ml

http

://w

ww

.dru

gs.c

om/v

et/fl

unaz

ine-

inje

ctab

le-s

olut

ion.

htm

lht

tp://

ww

w.d

rugs

.com

/vet

/flu-

nix-

d-

This

is al

so o

ne o

f the

NSA

IDs,

all o

f whi

ch h

ave

exte

nsiv

e po

tent

ial a

dver

se si

de

effe

cts i

n hu

man

s inc

ludi

ng c

ardi

ovas

cula

r, ga

stroi

ntes

tinal

, kid

ney

and

eye

prob

lem

s.

The

NSA

IDs c

an b

e da

nger

ous f

or in

divi

dual

s with

blo

od d

isord

ers.

The

y ar

e al

so

cont

rain

dica

ted

durin

g pr

egna

ncy.

The

y al

so p

rese

nt si

gnifi

cant

risk

for p

eopl

e w

ith a

hi

story

of u

lcer

s or g

astro

inte

stina

l ble

edin

g. C

an c

ause

nau

sea,

abd

omin

al p

ain,

di

arrh

ea, h

eada

ches

, exc

itabi

lity,

and

ner

vous

syste

m p

robl

ems.

14

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

ivx.

htm

lht

tp://

ww

w.d

rugs

.com

/vet

/flun

ixam

ine

.htm

l50

.Fu

ralta

done

A

ntib

acte

rial

http

://w

ww

.che

mbl

ink.

com

/MSD

S/M

SDSF

iles/1

39-9

1-3_

Sigm

a-A

ldric

h.pd

f

May

cau

se c

ance

r in

hum

ans,

but v

ery

little

kno

wn

abou

t effe

ct o

n hu

man

s bec

ause

th

e dr

ug h

as n

ot b

een

teste

d on

hum

ans a

nd th

e po

tent

ial s

ide

effe

cts u

pon

inge

stion

ar

e un

know

n.

51.

Fura

zolid

one

Ant

ibac

teria

l:Fu

rall

Furo

x A

eros

ol P

owde

r U

sed

in h

uman

s as a

n an

ti-di

arrh

eal

21 C

FR §

524

.100

5 -

“Not

for u

se in

hor

ses i

nten

ded

for f

ood.

” ht

tp://

msd

s.far

nam

.com

/m00

0394

.ht

m http

://w

ww

.dru

gs.c

om/v

et/fu

razo

lido

ne-a

eros

ol-p

owde

r.htm

lFe

dera

l law

pro

hibi

ts th

e us

e of

this

prod

uct i

n fo

od-p

rodu

cing

ani

mal

s.

Con

tain

s che

mic

als k

now

n to

the

state

of C

alifo

rnia

to c

ause

can

cer.

Shou

ld o

nly

be ta

ken

unde

r stri

ct m

edic

al o

vers

ight

; dan

gero

us if

take

n w

ith a

lcoh

ol,

whe

n pr

egna

nt, o

r for

indi

vidu

als w

ith c

erta

in b

lood

diso

rder

s.

Adv

erse

effe

cts i

nclu

de h

eada

che,

stom

ach

upse

t, na

usea

, vom

iting

, diz

zine

ss o

r w

eakn

ess,

feve

r, sk

in ra

sh, i

tchi

ng, m

uscl

e ac

hes,

flush

ing,

bre

athi

ng tr

oubl

e. T

his

med

icat

ion

may

cau

se th

e ur

ine

to tu

rn b

row

n in

col

or.

52.

Furo

sem

ide

Diu

retic

:La

sixU

sed

in h

uman

s and

hor

ses

May

cau

se p

ancr

eatit

is, ja

undi

ce, a

nore

xia,

par

esth

esia

s, ot

otox

icity

, blo

od d

yscr

asia

s, di

zzin

ess,

rash

, urti

caria

, pho

tose

nsiti

vity

, fev

er, t

hrom

boph

lebi

tis, r

estle

ssne

ss.

http

://w

ww

.pdr

.net

/sear

ch/se

arch

Res

ult.a

spx?

sear

chC

riter

ia=F

uros

emid

e

53.

Gen

tam

icin

sulfa

te

solu

tion

Ant

ibio

tic:

Gen

tam

icin

solu

tion

Do

not u

se fo

r hor

ses i

nten

ded

for

hum

an c

onsu

mpt

ion.

ht

tp://

ww

w.d

rugs

.com

/vet

/gen

tam

ici

n-su

lfate

-sol

utio

n.ht

ml

21 C

FR §

529

.104

4a

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

Can

cau

se se

vere

hea

ring

and

kidn

ey p

robl

ems.

May

cau

se d

izzi

ness

, ve

rtigo

, rin

ging

in th

e ea

rs, h

earin

g lo

ss, n

umbn

ess,

mus

cle

twitc

hing

or w

eakn

ess,

diffi

culty

br

eath

ing,

dec

reas

ed u

rinat

ion,

rash

, itc

hing

, or s

ore

thro

at.

Inte

ract

ion

and

pote

ntia

l ha

rm w

ith o

ther

dru

gs c

an c

ause

adv

erse

reac

tions

.

54.

Gen

tian

viol

et

Blu

e-K

ote

Usu

ally

use

d to

pica

lly o

n hu

man

s. U

nkno

wn

side

effe

cts u

pon

inge

stion

.

15

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

Topi

cal o

intm

ent,

antis

eptic

, pr

otec

tive

wou

nd d

ress

ing.

N

ot fo

r use

on

food

pro

duci

ng

anim

als.

http

://w

ww

.dru

gs.c

om/v

et/d

r-nay

lor-

blu-

kote

.htm

lht

tp://

ww

w.d

rnay

lor.c

om/in

dex.

php?

optio

n=co

m_c

onte

nt&

task

=blo

gcat

ego

ry&

id=2

0&Ite

mid

=47

“Not

for u

se o

n an

imal

s int

ende

d fo

r fo

od.”

http

://w

ww

.hor

sesu

pplie

splu

s.com

/ant

isept

ics.h

tml

55.

HC

lC

ompo

nent

of D

exiu

m in

ject

ion

http

://w

ww

.dru

gs.c

om/v

et/d

exiu

m-

inje

ctio

n.ht

ml

Ver

y ha

zard

ous i

f tou

ched

; not

fully

teste

d on

hum

ans;

may

be

fata

l if i

nhal

ed o

r sw

allo

wed

. C

ause

s irri

tatio

n an

d bu

rnin

g, u

lcer

atio

n, o

r per

fora

tion

of th

e ga

stroi

ntes

tinal

trac

t and

resu

ltant

per

itoni

tis, g

astri

c he

mor

rhag

e an

d in

fect

ion.

Can

al

so c

ause

nau

sea,

vom

iting

(with

“co

ffee

grou

nd”

emes

is), d

iarrh

ea, t

hirs

t, di

fficu

lty

swal

low

ing,

saliv

atio

n, c

hills

, fev

er, u

neas

ines

s, sh

ock,

stric

ture

s and

sten

osis

(eso

phog

eal,

gastr

ic, p

ylor

ic).

May

affe

ct b

ehav

ior (

exci

tem

ent),

the

card

iova

scul

ar

syste

m (w

eak

rapi

d pu

lse, t

achy

card

ia),

resp

iratio

n (s

hallo

w re

spira

tion)

, and

urin

ary

syste

m (k

idne

ys- r

enal

failu

re, n

ephr

itis)

. A

cute

exp

osur

e vi

a in

hala

tion

or in

gesti

on

can

also

cau

se e

rosio

n of

toot

h en

amel

. 56

.H

yalu

rona

te so

dium

A

rthrit

is tre

atm

ent

Lege

nd

Lege

nd in

ject

able

21

CFR

§ 5

22.1

145

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” -

“Not

for u

se in

hor

ses i

nten

ded

for f

ood.

” ht

tp://

ww

w.b

ayer

dvm

.com

/pro

duct

s/leg

end/

lege

nd.c

fmht

tp://

ww

w.d

rugs

.com

/vet

/lege

nd-

mul

ti-do

se-h

yalu

rona

te-s

odiu

m-

inje

ctab

le-s

olut

ion.

htm

l

May

cau

se g

astro

inte

stina

l tra

ct in

form

atio

n w

ith n

ause

a an

d vo

miti

ng.

It m

ay a

ffect

bl

ood

(nor

moc

ytic

ane

mia

, cha

nge

in le

ukoc

yte

coun

t), m

etab

olism

, beh

avio

r (at

axia

, co

nvul

sions

), re

spira

tion

(resp

irato

ry st

imul

atio

n), a

nd u

rinar

y sy

stem

. Th

e to

xico

logi

cal p

rope

rties

of t

his s

ubsta

nce

have

not

bee

n fu

lly in

vesti

gate

d.

http

://w

ww

.scie

ncel

ab.c

om/m

sds.p

hp?m

sdsI

d=99

2427

6

57.

Hya

luro

nic

acid

sodi

um

salt

Poly

glyc

an

May

cau

se g

astro

inte

stina

l irri

tatio

n, a

ffect

blo

od, m

etab

olism

and

beh

avio

r. T

he

dang

ers u

pon

inge

stion

by

hum

ans h

as n

ot b

een

fully

inve

stiga

ted.

16

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

For u

se o

nly

as a

surg

ical

lava

ge in

an

imal

s not

inte

nded

for f

ood

use.

ht

tp://

ww

w.m

edi-

vet.c

om/P

olyg

lyca

n.as

pxA

lso u

sed

in ra

ce h

orse

s prio

r to

a ra

ce.

58.

Hyd

roxy

zine

Pam

oate

A

nti-a

nxie

ty in

hum

ans a

nd

preo

pera

tive

seda

tion.

A

ntih

istam

ine,

ant

i-itc

hing

and

se

dativ

e in

ani

mal

s. ht

tp://

ww

w.d

rsfo

sters

mith

.com

/pro

duc

t/pro

d_di

spla

y.cf

m?p

catid

=206

78

May

impa

ir m

enta

l and

phy

sical

abi

litie

s in

elde

rly, m

ay p

oten

tiate

oth

er m

edic

atio

ns,

and

not f

or u

se b

y pr

egna

nt o

r nur

sing

mot

hers

. ht

tp://

ww

w.p

dr.n

et/d

rugp

ages

/con

cise

mon

ogra

ph.a

spx?

conc

ise=1

096

59.

Hyo

scin

e bu

tylb

rom

ide

Bus

copa

n Sc

opol

amin

e A

ntisp

asm

odic

; col

ic p

ain

relie

f. ht

tp://

ww

w.d

rugs

.com

/vet

/bus

copa

n-ste

rile-

solu

tion-

can.

htm

l

Pote

ntia

l adv

erse

effe

cts i

nclu

de b

lurre

d vi

sion,

seve

re a

llerg

ic re

actio

ns, c

onfu

sion,

ur

inar

y pr

oble

ms,

and

moo

d ch

ange

s. w

ww

.dru

gs.c

om/sf

x/sc

opol

amin

e-sid

e-ef

fect

s.htm

l

60.

Isof

lura

ne

Surg

ical

ane

sthet

ic

21 C

FR §

529

.118

6 -

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

MSD

S re

ports

no

info

rmat

ion

on to

xici

ty u

pon

inge

stion

.

61.

Isop

araf

finic

Pet

role

um

Solv

ent

Fly

Con

trol:

Farn

am B

ronc

o G

old

(spr

ay)

Farn

am W

ipe

http

://m

sds.f

arna

m.c

om/m

0016

50.h

tm ht

tp://

msd

s.far

nam

.com

/m00

0490

.ht

m

Unk

now

n hu

man

toxi

city

and

side

effe

cts a

fter i

nges

tion.

62.

Iver

mec

tinD

ewor

mer

s: A

gri-m

ectin

Pas

te

Bim

ectin

Pas

te

Eque

ll Pa

ste

Can

act

for u

p to

twel

ve m

onth

s; ca

rcin

ogen

icity

not

stud

ied;

not

reco

mm

ende

d fo

r pr

egna

nt w

omen

; dist

ribut

es in

to b

reas

t milk

. A

dver

se re

actio

ns in

clud

e pr

uritu

s, ed

ema,

pap

ular

/pus

tula

r/fra

nk u

rtica

rial r

ash,

fe

ver,

axill

ary/

cerv

ical

/ingu

inal

lym

phad

enop

athy

, arth

ralg

ia/sy

novi

tis, l

imbi

tis,

tach

ycar

dia,

per

iphe

ral e

dem

a, le

ukop

enia

, eos

inop

hilia

17

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

Equi

max

Farn

am Iv

erca

re

Hor

se H

ealth

Iver

mec

tin

Iver

care

pas

te

ProM

etin

E™

Pas

te

Zim

ecte

rin G

old

Zim

ecte

rin P

aste

A

lso fo

und

in h

uman

ant

helm

intic

co

mpo

unds

21

CFR

§ 5

20.1

192

- Pa

ste

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” 21

CFR

§ 1

194

- M

eal

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” 21

CFR

§ 1

195

- Li

quid

-

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

21 C

FR §

1198

-

Iver

mec

tin a

nd p

razi

quan

tel

paste

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” ht

tp://

ww

w.d

rugs

.com

/vet

/agr

i-m

ectin

-pas

te-1

-87.

htm

lht

tp://

ww

w.d

rugs

.com

/vet

/agr

i-m

ectin

-pas

te-1

-87.

htm

lht

tp://

ww

w.d

avisa

ndla

wre

nce.

com

/1-

x-6-

08-g

.htm

lht

tp://

ww

w.h

orse

heal

thus

a.co

m/d

etai

ls/Eq

uell-

Paste

/37-

105.

htm

lht

tp://

ww

w.e

quim

axho

rse.

com

/

http

://w

ww

.pdr

.net

/sear

ch/se

arch

Res

ult.a

spx?

sear

chC

riter

ia=i

verm

ectin

18

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

63.

Ket

opro

fen

NSA

ID:

Ket

ofen

Use

d as

NSA

ID in

hor

ses a

nd

hum

ans.

21 C

FR §

522

.122

5 -

“Not

for u

se in

hor

ses i

nten

ded

for f

ood.

” ht

tp://

ww

w.d

rugs

.com

/vet

/ket

ofen

.ht

ml

Ket

opro

fen

is on

e of

the

NSA

IDs,

all o

f whi

ch h

ave

exte

nsiv

e po

tent

ial a

dver

se si

de

effe

cts i

n hu

man

s inc

ludi

ng c

ardi

ovas

cula

r, ga

stroi

ntes

tinal

, kid

ney

and

eye

prob

lem

s.

The

NSA

IDs c

an b

e da

nger

ous f

or in

divi

dual

s with

blo

od d

isord

ers.

The

y ar

e al

so

cont

rain

dica

ted

durin

g pr

egna

ncy.

The

y al

so p

rese

nt si

gnifi

cant

risk

for p

eopl

e w

ith a

hi

story

of u

lcer

s or g

astro

inte

stina

l ble

edin

g. C

an c

ause

nau

sea,

abd

omin

al p

ain,

di

arrh

ea, h

eada

ches

, exc

itabi

lity,

and

ner

vous

syste

m p

robl

ems.

64.

Levo

thyr

oxin

e So

dium

Th

yro-

L Th

yroi

d re

plac

emen

t hor

mon

e.

http

://w

ww

.dru

gs.c

om/v

et/th

yro-

l.htm

l

This

artif

icia

l thy

roid

hor

mon

e ca

n ex

acer

bate

thyr

oid

and

hype

rtens

ion

prob

lem

s in

susc

eptib

le in

divi

dual

s.

http

://w

ww

.pdr

.net

/sear

ch/se

arch

Res

ult.a

spx?

sear

chC

riter

ia=L

evot

hyro

xine

+Sod

ium

65.

Lupr

ostio

l Fo

r con

trol o

f rep

rodu

ctiv

e cy

cles

an

d in

duci

ng te

rmin

atio

n of

pr

egna

ncy.

21

USC

§ 5

22.1

290

- so

lutio

n -

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

- “L

abel

ing

shal

l bea

r the

fo

llow

ing

state

men

ts: W

arni

ng:

Wom

en o

f chi

ld-b

earin

g ag

e,

asth

mat

ics,

and

pers

ons w

ith

bron

chia

l and

oth

er re

spira

tory

pr

oble

ms s

houl

d ex

erci

se e

xtre

me

caut

ion

whe

n ha

ndlin

g th

is pr

oduc

t.

In th

e ea

rly st

ates

, wom

en m

ay b

e un

awar

e of

thei

r pre

gnan

cies

...”

Dan

gero

us fo

r chi

ldre

n, p

regn

ant a

nd la

ctat

ing

mot

hers

, ind

ivid

uals

with

resp

irato

ry

prob

lem

s. C

an c

ause

hor

mon

al e

ffect

s whe

n ta

ken.

66.

Mep

ivac

aine

A

nesth

etic

21

CFR

§ 5

22.1

372

- “N

ot fo

r use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

Bec

ause

this

is an

inje

ctab

le d

rug,

stud

ies h

ave

not b

een

done

on

the

dang

ers o

f in

gesti

on.

67.

Met

hoca

rbam

ol

Rob

axin

M

uscl

e re

laxa

nt in

ani

mal

s and

hu

man

s.

Pote

ntia

l adv

erse

reac

tions

incl

ude

light

head

edne

ss, d

izzi

ness

, dro

wsin

ess,

naus

ea,

urtic

aria

, pru

ritus

, ras

h, c

onju

nctiv

itis,

nasa

l con

gesti

on, b

lurre

d vi

sion,

hea

dach

e,

feve

r, se

izur

es, s

ynco

pe, f

lush

ing.

ht

tp://

ww

w.p

dr.n

et/se

arch

/sear

chR

esul

t.asp

x?se

arch

Crit

eria

=Met

hoca

rbam

ol

19

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

http

://w

ww

.pet

plac

e.co

m/d

rug-

libra

ry/m

etho

carb

amol

-roba

xin-

v/pa

ge1.

aspx

68.

Met

hyl S

alic

ylat

e Sc

arle

t Oil

Wou

nd d

ress

ing

for h

orse

s. M

uscl

e an

d jo

int p

ain

relie

f in

hum

ans.

Not

for u

se o

n an

imal

s int

ende

d fo

r fo

od.

http

://w

ww

.dru

gs.c

om/v

et/sc

arle

t-oi

l.htm

l

“Whe

n in

geste

d, th

e hi

ghly

con

cent

rate

d liq

uid

met

hyl s

alic

ylat

e in

the

form

of

win

terg

reen

oil,

as w

ith o

ther

vol

atile

oils

, can

indu

ce v

omiti

ng a

nd is

a n

otor

ious

so

urce

for s

ever

e, o

ften

fata

l poi

soni

ngs.”

ht

tp://

ww

w.d

rugs

.com

/npp

/win

terg

reen

.htm

lD

ange

rous

if u

sed

in c

onju

nctio

n w

ith o

ther

ana

lges

ics,

antic

oagu

lant

s, ste

roid

s, N

SAID

s, al

coho

l, an

d di

uret

ics.

http

://w

ww

.pdr

.net

/sear

ch/se

arch

Res

ult.a

spx?

sear

chC

riter

ia=M

ethy

l+Sa

licyl

ate

69.

Met

hyla

ndro

sten

edio

l M

etha

ndrio

l A

nabo

lic st

eroi

d U

sed

as g

row

th st

imul

ator

and

ste

roid

in h

orse

s and

hum

ans.

http

://w

ww

.dru

gs.c

om/in

tern

atio

nal/

met

hand

riol.h

tml

Can

cau

se e

strog

enic

(fem

ale

horm

one)

and

and

roge

nic

(mal

e ho

rmon

e) e

ffect

s. St

eroi

ds sh

ould

be

take

n un

der a

doc

tor’s

supe

rvisi

on a

nd h

ave

mul

tiple

sign

ifica

nt

adve

rse

affe

cts i

nclu

ding

seve

re a

llerg

ic re

actio

ns, h

orm

onal

cha

nges

, cha

nges

in

men

strua

l fun

ctio

ns, m

enta

l and

moo

d ch

ange

s, re

spira

tory

pro

blem

s, na

usea

and

vo

miti

ng, j

oint

swel

ling,

visi

on c

hang

es, a

nd u

nusu

al w

eigh

t gai

n.

70.

Met

hylp

redn

isolo

ne

Hum

an a

nd h

orse

ster

oid

21 C

FR §

522

.141

0 -

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

Ster

oids

shou

ld b

e ta

ken

unde

r a d

octo

r’s su

perv

ision

and

hav

e m

ultip

le si

gnifi

cant

ad

vers

e af

fect

s inc

ludi

ng se

vere

alle

rgic

reac

tions

, hor

mon

al c

hang

es, c

hang

es in

m

enstr

ual f

unct

ions

, men

tal a

nd m

ood

chan

ges,

resp

irato

ry p

robl

ems,

naus

ea a

nd

vom

iting

, joi

nt sw

ellin

g, v

ision

cha

nges

, and

unu

sual

wei

ght g

ain.

71.

Met

roni

dazo

le

Ant

ibio

tic in

hum

ans a

nd h

orse

s (F

lagy

l) ht

tp://

ww

w.w

edge

woo

dpet

rx.c

om/le

arni

ng-c

ente

r/pro

fess

iona

l-m

onog

raph

s/met

roni

dazo

le-fo

r-ve

terin

ary-

use-

ab.h

tml

This

drug

can

cau

se g

astro

inte

stina

l pro

blem

s, se

rious

alle

rgic

reac

tions

in se

nsiti

ve

indi

vidu

als,

flu-li

ke sy

mpt

oms,

seiz

ures

, enc

epha

lopa

thy,

ase

ptic

men

ingi

tis,

perip

hera

l neu

ropa

thy,

nau

sea

and

vom

iting

, hea

dach

e, a

nore

xia

and

neut

rope

nia.

ht

tp://

ww

w.p

dr.n

et/se

arch

/sear

chR

esul

t.asp

x?se

arch

Crit

eria

=Met

roni

dazo

le

72.

Mox

idec

tinQ

uest

Gel

Q

uest

Plus

A

ntip

aras

itic

(dew

orm

ers)

N

ot fo

r hor

ses o

r pon

ies i

nten

ded

for

hum

an c

onsu

mpt

ion.

ht

tp://

ww

w.fd

a.go

v/A

nim

alV

eter

inar

y/G

uida

nceC

ompl

ianc

eEnf

orce

men

t/

Ver

y lim

ited

testi

ng o

n hu

man

s – p

oten

tial a

dver

se e

ffect

s stil

l unk

now

n.

20

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

Com

plia

nceE

nfor

cem

ent/u

cm16

8782

.htm

21 C

FR §

520

.145

2; 5

20.1

463

- G

el

- “N

ot fo

r use

in h

orse

s and

pon

ies

inte

nded

for f

ood.

” ht

tp://

ww

w.d

rugs

.com

/vet

/que

st-pl

us-e

quin

e-or

al-g

el.h

tml

73.

N-(2

-Eth

ylhe

xyl)-

5-no

rbor

nene

-2,3

-di

carb

oxim

ide

Bug

Blo

ck (f

ly c

ontro

l) ht

tp://

abso

rbin

e.or

g/pr

oduc

ts/fly

cont

rol

/bug

-blo

ck-in

sect

icid

e-re

pelle

ntht

tp://

ww

w.st

atel

inet

ack.

com

/Con

ten

tFile

s/Ass

ocia

ted_

Con

tent

/abs

orbi

nebu

gblo

ckM

SDS.

pdf

“Har

mfu

l if i

nges

ted.

” B

ug B

lock

fly

cont

rol h

as m

ultip

le a

dver

se e

ffect

s if

swal

low

ed b

y hu

man

s. ht

tp://

ww

w.st

atel

inet

ack.

com

/Con

tent

File

s/Ass

ocia

ted_

Con

tent

/abs

orbi

nebu

gblo

ckM

SDS.

pdf

74.

N-a

cety

l-D-g

luco

sam

ine

10%

Poly

glyc

an

Post-

surg

ical

lava

ge o

f joi

nt

com

partm

ents.

“D

o no

t adm

inist

er to

ani

mal

s tha

t ar

e to

be

slaug

hter

ed fo

r foo

d.”

ww

w.a

rthro

dyna

mic

.com

/pol

ygly

can

/

Ingr

edie

nt in

Pol

ygly

can,

whi

ch in

clud

es w

arni

ng: “

For u

se o

nly

as a

surg

ical

lava

ge

in a

nim

als n

ot in

tend

ed fo

r foo

d us

e.”

http

://w

ww

.med

i-vet

.com

/Pol

ygly

can.

aspx

75.

Neo

myc

in S

ulfa

te

Ani

max

oin

tmen

t H

uman

and

ani

mal

ant

imic

robi

al,

anti-

fung

al st

eroi

d dr

ug

May

cau

se n

ause

a an

d vo

miti

ng, d

iarrh

ea, m

alab

sorp

tion

synd

rom

e, n

ephr

otox

icity

, ot

otox

icity

, neu

rom

uscu

lar b

lock

age,

neu

roto

xici

ty, f

etal

har

m.

Espe

cial

ly d

ange

rous

fo

r ind

ivid

uals

with

cer

tain

dise

ases

of t

he m

uscl

es.

http

://w

ww

.pdr

.net

/dru

gpag

es/c

onci

sem

onog

raph

.asp

x?co

ncise

=317

476

.N

itrof

uran

toin

Eq

uifu

rA

ntib

acte

rial f

or u

rinar

y tra

ct

infe

ctio

ns in

hor

ses a

nd h

uman

s. Th

is dr

ug is

not

to b

e ad

min

ister

ed to

ho

rses

that

are

to b

e sla

ught

ered

for

use

in fo

od.

http

://w

ww

.dru

gs.c

om/v

et/e

quifu

r-ca

n.ht

ml

Adv

erse

effe

cts i

nclu

de h

yper

sens

itivi

ty re

actio

ns, p

ulm

onar

y/he

patic

/psy

chot

ic

reac

tions

, per

iphe

ral n

euro

path

y, n

ause

a an

d vo

miti

ng, a

nore

xia,

diz

zine

ss, e

xfol

iativ

e de

rmat

itis,

anap

hyla

xis,

hem

atol

ogic

abn

orm

aliti

es, c

yano

sis, a

ngio

edem

a, a

sthen

ia.

http

://w

ww

.pdr

.net

/dru

gpag

es/c

onci

sem

onog

raph

.asp

x?co

ncise

=383

21

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

77.

Nitr

ofur

azon

e N

ider

m O

intm

ent

Ant

ibac

teria

l oin

tmen

t, bu

rns,

skin

gr

afts.

21 C

FR §

524

.158

0b

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” -

“Fed

eral

law

pro

hibi

ts th

e us

e of

th

is pr

oduc

t in

food

-pro

duci

ng

anim

als.”

Fe

dera

l law

pro

hibi

ts th

e ad

min

istra

tion

of th

is pr

epar

atio

n to

an

imal

s tha

t pro

duce

food

or t

hat a

re

inte

nded

for c

onsu

mpt

ion

as fo

od.

http

://w

ww

.dru

gs.c

om/v

et/n

ider

m-

oint

men

t-can

.htm

l

Ver

y to

xic

to h

uman

s. ht

tp://

ww

w.sc

ienc

elab

.com

/msd

s.php

?msd

sId=

9926

271

78.

N-O

ctyl

Bic

yclo

hept

ene

Dic

arbo

xim

ide

Farn

am R

oll-O

n R

epel

lent

Fl

y sp

ray

http

://m

sds.f

arna

m.c

om/m

0000

18.h

tm

Acc

ordi

ng to

the

man

ufac

ture

r, Fa

rnam

Rol

l-On

Rep

elle

nt is

“ha

rmfu

l if s

wal

low

ed.”

79.

Nys

tatin

A

ntim

icro

bial

, ant

ifung

al a

nd st

eroi

dA

nim

ax o

intm

ent

Myc

osta

tin

Bio

-Sta

tinFo

r use

in h

uman

s and

hor

ses w

ith

thru

sh.

Adv

erse

reac

tions

incl

ude

oral

irrit

atio

n, se

nsiti

zatio

n, d

iarrh

ea, n

ause

a an

d vo

miti

ng,

gastr

oint

estin

al d

istur

banc

es, r

ash,

urti

caria

, Ste

vens

-Joh

nson

synd

rom

e.

http

://w

ww

.pdr

.net

/sear

ch/se

arch

Res

ult.a

spx?

sear

chC

riter

ia=N

ysta

tinSe

e al

so:

http

://w

ww

.ncb

i.nlm

.nih

.gov

/pub

med

heal

th/P

MH

0000

767/

http

://w

ww

.nlm

.nih

.gov

/med

linep

lus/d

rugi

nfo/

med

s/a68

2758

.htm

l

80.

Om

epra

zole

Tr

eatm

ent f

or u

lcer

s in

hors

es a

nd

hum

ans.

Gas

troga

rd21

CFR

§ 5

20.1

615

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

” ht

tp://

gastr

ogar

d.us

.mer

ial.c

om/fa

q.s

htm

l

Adv

erse

reac

tions

incl

ude

head

ache

, dia

rrhea

, abd

omin

al p

ain,

nau

sea

and

vom

iting

, fe

ver,

resp

irato

ry d

isord

ers,

seve

re a

llerg

ic re

actio

ns, i

rregu

lar h

eartb

eat,

brui

sing

and

blee

ding

.ht

tp://

ww

w.p

dr.n

et/se

arch

/sear

chR

esul

t.asp

x?se

arch

Crit

eria

=Om

epra

zole

81.

Oxi

bend

azol

e A

nthe

lcid

e de

wor

mer

“D

o no

t allo

w p

rodu

ct to

ent

er d

rinki

ng w

ater

supp

lies,

was

te w

ater

or s

oil.”

22

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

21 C

FR §

520

.163

8 -

paste

-

“Not

for u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

21 C

FR §

520

.163

8 -

Susp

ensio

n -

“Not

for u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

Not

for u

se in

hor

ses i

nten

ded

for

hum

an c

onsu

mpt

ion.

ht

tp://

ww

w.d

rugs

.com

/vet

/ant

helc

ide

-eq-

equi

ne-w

orm

er-p

aste

.htm

l

http

://w

ww

.seqc

hem

.com

/safe

tysh

eet.p

hp?S

QIn

dex=

SRP0

1249

1o

82.

Para

chlo

rom

etax

ylen

ol

Scar

let O

il N

ot fo

r use

on

anim

als i

nten

ded

for

food

.ht

tp://

ww

w.d

rugs

.com

/vet

/scar

let-

oil.h

tml

May

cau

se b

urni

ng o

f mou

th, t

hroa

t and

stom

ach,

if in

geste

d.

http

://su

rfact

antsi

nc.c

om/p

df/S

urci

de%

20PC

MX

-USP

%20

MSD

S.pd

f

83.

Phen

olRe

d-K

ote

Not

for u

se o

n an

imal

s int

ende

d fo

r fo

od.

http

://w

ww

.dru

gs.c

om/v

et/d

r-nay

lor-

red-

kote

.htm

l

Phen

ol is

con

sider

ed to

be

quite

toxi

c to

hum

ans v

ia o

ral e

xpos

ure.

Ano

rexi

a,

prog

ress

ive

wei

ght l

oss,

diar

rhea

, ver

tigo,

saliv

atio

n, a

dar

k co

lora

tion

of th

e ur

ine,

an

d bl

ood

and

liver

effe

cts h

ave

been

repo

rted

in c

hron

ical

ly (l

ong-

term

) exp

osed

hu

man

s. A

nim

al st

udie

s hav

e re

porte

d re

duce

d fe

tal b

ody

wei

ghts,

gro

wth

re

tard

atio

n, a

nd a

bnor

mal

dev

elop

men

t in

the

offs

prin

g of

ani

mal

s exp

osed

to p

heno

l by

the

oral

rout

e.

http

://w

ww

.epa

.gov

/ttn/

atw

/hlth

ef/p

heno

l.htm

l84

.Ph

enyl

buta

zone

N

SAID

:B

utaz

one

400

But

azon

e 10

00

Buta

zone

Con

cent

rate

Bu

te p

aste

B

uteq

uine

21

USC

§52

0.17

70a

- Ta

blet

s and

bol

uses

-

Dog

s and

hor

ses

- “D

o no

t use

in h

orse

s int

ende

d fo

r hum

an c

onsu

mpt

ion.

.”

21 U

SC §

522

.172

0

Serio

us a

nd fa

tal a

dver

se e

ffect

s hav

e be

en re

porte

d fro

m in

gesti

on o

f Ph

enyl

buta

zone

, inc

ludi

ng b

one

mar

row

supp

ress

ion

and

apla

stic

anem

ia.

Ban

ned

in

Am

eric

a fo

r hum

an u

se.

Nic

hola

s Dod

man

, Nic

olas

Blo

ndel

l, A

nn M

. Mar

ini,

“Ass

ocia

tion

of p

heny

lbut

azon

e us

age

with

hor

ses b

ough

t for

slau

ghte

r: A

pub

lic

heal

th ri

sk”,

FO

OD

AN

D C

HEM

ICA

LTO

XIC

OLO

GY

48

(201

0) 1

270–

74.

“Phe

nylb

utaz

one

is kn

own

to in

duce

blo

od d

yscr

asia

s, in

clud

ing

apla

stic

anem

ia,

leuk

open

ia, a

gran

uloc

ytos

is, th

rom

bocy

tope

nia

and

deat

hs. H

yper

sens

itivi

ty re

actio

ns

of th

e se

rum

-sic

knes

s typ

e ha

ve a

lso b

een

repo

rted.

In a

dditi

on, p

heny

lbut

azon

e is

a ca

rcin

ogen

, as d

eter

min

ed b

y th

e N

atio

nal T

oxic

olog

y Pr

ogra

m.”

ht

tp://

ww

w.fd

a.go

v/A

nim

alV

eter

inar

y/N

ewsE

vent

s/C

VM

Upd

ates

/ucm

1240

78.

htm

Phen

ylbu

tazo

ne is

esp

ecia

lly p

robl

emat

ic fo

r pat

ient

s with

a h

istor

y of

asth

ma

atta

cks,

hive

s, or

oth

er a

llerg

ic re

actio

ns to

asp

irin

or o

ther

NSA

IDs.

It al

so sh

ould

be

avoi

ded

by p

atie

nts w

ith p

eptic

ulc

er d

iseas

e or

poo

r kid

ney

func

tion,

sinc

e th

is m

edic

atio

n

23

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

- In

ject

ion

- D

ogs a

nd h

orse

s -

“Not

for u

se in

ani

mal

s int

ende

d fo

r foo

d.”

http

://ho

rseb

ackm

agaz

ine.

com

/hb/

arc

hive

s/131

84ht

tp://

ww

w.fa

rmve

t.com

/pc-

1500

-16

3-bu

te-p

aste

-12-

gm.a

spx

http

://w

ww

.dru

gs.c

om/v

et/b

uteq

uine

-ca

n.ht

ml

http

://tu

esda

ysho

rse.

wor

dpre

ss.c

om/t

ag/c

fia/

can

aggr

avat

e bo

th c

ondi

tions

. Phe

nylb

utaz

one

is ge

nera

lly u

sed

with

cau

tion

in

patie

nts t

akin

g bl

ood

thin

ning

med

icat

ions

(ant

icoa

gula

nts)

, suc

h as

war

farin

(C

oum

adin

), be

caus

e of

an

incr

ease

d ris

k of

ble

edin

g. P

atie

nts t

akin

g lit

hium

can

de

velo

p to

xic

bloo

d lit

hium

leve

ls. A

dditi

onal

ly, p

atie

nts t

akin

g cy

clos

porin

e (S

andi

mm

une)

can

dev

elop

kid

ney

toxi

city

.

85.

Pipe

rony

l But

oxid

e R

epel

-XP

Fl

y co

ntro

l D

o no

t use

on

hors

es in

tend

ed fo

r hu

man

con

sum

ptio

n.

http

://w

ww

.dru

gs.c

om/v

et/re

pel-x

p-em

ulsif

iabl

e-fly

-spr

ay.h

tml

Pote

ntia

l dan

gers

to h

uman

s are

unk

now

n: “

Dat

a ar

e no

t ava

ilabl

e fro

m a

ccid

enta

l po

isoni

ngs,

occu

patio

nal e

xpos

ures

, or e

pide

mio

logi

cal s

tudi

es re

gard

ing

the

repr

oduc

tive

and

deve

lopm

enta

l tox

icity

of p

iper

onyl

but

oxid

e.”

np

ic.o

rst.e

du/fa

ctsh

eets

/pbo

tech

.pdf

Inge

stio

n ca

n ca

use

vom

iting

and

dia

rrhe

a. P

estic

ide

Act

ion

Net

wor

k N

orth

A

mer

ica.

Pip

eron

yl B

utox

ide,

ht

tp://

ww

w.p

estic

idei

nfo.

org/

Det

ail_

Che

mic

al.js

p?R

ec_I

d=PC

3324

0Th

e EP

A c

lass

ifies

pip

eron

yl b

utox

ide

as a

gro

up C

car

cino

gen,

a p

ossi

ble

hum

an

carc

inog

en.

Envi

ronm

enta

l Pro

tect

ion

Age

ncy.

Rer

egis

tratio

n El

igib

ility

Dec

isio

n fo

r Pip

eron

yl B

utox

ide.

(Jun

e 20

06).

http

://w

ww

.epa

.gov

/opp

0000

1/re

regi

stra

tion/

RED

s/pi

pero

nyl_

red.

pdf

86.

Poly

sulfa

ted

Gly

cosa

min

ogly

can

A

dequ

an

Join

t tre

atm

ent.

21 U

SC §

522

.185

0 -

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

Dat

a on

hum

an sa

fety

, per

tain

ing

to c

onsu

mpt

ion

of d

rug

resid

ues i

n fo

od, w

ere

not

requ

ired

for a

ppro

val o

f thi

s sup

plem

enta

l new

ani

mal

dru

g. T

he d

rug

is ap

prov

ed fo

r us

e on

ly in

hor

ses t

hat a

re n

ot to

be

used

for f

ood

and

is to

be

labe

led

“’N

ot fo

r use

in

hors

es in

tend

ed fo

r foo

d.’”

ht

tp://

ww

w.fd

a.go

v/A

nim

alV

eter

inar

y/Pr

oduc

ts/A

ppro

vedA

nim

alD

rugP

rodu

cts/F

OI

AD

rugS

umm

arie

s/ucm

0548

46.h

tmB

ased

on

the

form

ulat

ion

of th

e dr

ug, h

uman

s cou

ld d

evel

op a

naph

ylax

is or

exc

essiv

e bl

eedi

ng a

s the

sulfa

ted

prot

eogl

ycan

s are

ant

icoa

gula

nts.

87.

Pona

zuri

l A

ntip

roto

zoal

M

arqu

is pa

ste; M

arqu

is 21

CFR

§ 5

20.1

855

- H

orse

s onl

y -

“Not

for u

se in

hor

ses i

nten

ded

Unk

now

n sid

e ef

fect

s and

adv

erse

reac

tions

in h

uman

s ing

estin

g Po

nazu

ril.

“Dat

a on

hum

an sa

fety

, per

tain

ing

to c

onsu

mpt

ion

of d

rug

resid

ues i

n fo

od, w

ere

not

requ

ired

for a

ppro

val o

f thi

s sup

plem

enta

l new

ani

mal

dru

g. T

he d

rug

is ap

prov

ed fo

r us

e on

ly in

hor

ses t

hat a

re n

ot to

be

used

for f

ood

and

is to

be

labe

led

‘Not

for u

se in

ho

rses

inte

nded

for f

ood.

’”

Free

dom

of I

nfor

mat

ion

Sum

mar

y, O

rigin

al N

ew A

nim

al D

rug

App

licat

ion,

NA

DA

24

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

for f

ood.

” “N

ot fo

r use

in h

orse

s int

ende

d fo

r fo

od.”

http

://w

ww

.dru

gs.c

om/v

et/m

arqu

is-15

-w-w

-pon

azur

il-an

tipro

tozo

al-o

ral-

paste

.htm

l

141-

188

(Mar

quis)

, ww

w.fd

a.go

v/do

wnl

oads

/Ani

mal

Vet

erin

ary/

.../u

cm11

7581

.pdf

88.

Pral

leth

rin

Inse

ctic

ide

Mos

quito

Hal

t Fl

y sp

ray

http

://w

ww

.dru

gs.c

om/v

et/m

osqu

ito-

halt-

repe

llent

-spr

ay-fo

r-hor

ses.h

tml

Pote

ntia

l poi

soni

ng, h

eada

che,

diz

zine

ss, n

ause

a, a

nd se

izur

e.

http

://w

ww

.pes

ticid

einf

o.or

g/D

etai

l_C

hem

ical

.jsp?

Rec

_Id=

PC35

755

“Pyr

ethr

oid

inge

stion

giv

es ri

se w

ithin

min

utes

to a

sore

thro

at, n

ause

a, v

omiti

ng a

nd

abdo

min

al p

ain.

The

re m

ay b

e m

outh

ulc

erat

ion,

incr

ease

d se

cret

ions

and

/or

dysp

hagi

a. S

yste

mic

effe

cts o

ccur

4-4

8 ho

urs a

fter e

xpos

ure.

Diz

zine

ss, h

eada

che

and

fatig

ue a

re c

omm

on, a

nd p

alpi

tatio

ns, c

hest

tight

ness

and

blu

rred

visio

n le

ss

frequ

ent.

Com

a an

d co

nvul

sions

are

the

prin

cipa

l life

-thre

aten

ing

feat

ures

. Mos

t pa

tient

s rec

over

with

in 6

day

s. . .

.”

S.M

. Bra

dber

ry e

t al.,

Poiso

ning

Due

to

Pyre

thro

ids,

Toxi

col R

ev. 2

4(2)

:93-

106

(200

5) (q

uotin

g ab

strac

t).

89.

Praz

iqua

ntel

D

ewor

mer

Fo

r hor

ses a

nd h

uman

s Eq

uim

axQ

uest

Plus

Zi

mec

terin

Gol

d ht

tp://

ww

w.e

quim

axho

rse.

com

/ht

tp://

ww

w.d

rugs

.com

/vet

/que

st-pl

us-e

quin

e-or

al-g

el.h

tml

“Not

for u

se in

hum

ans.”

(Z

imec

terin

)ht

tp://

ww

w.z

imec

terin

.com

/Zim

ecte

rin

Gol

d/in

dex.

htm

l?=5

0

Ava

ilabl

e by

pre

scrip

tion

only

and

to b

e ta

ken

only

und

er th

e m

onito

ring

of a

ph

ysic

ian.

C

ontra

indi

cate

d fo

r peo

ple

with

pre

-exi

ting

cond

ition

s inv

olvi

ng th

e liv

er, k

idne

y, o

r he

art.

Praz

iqua

ntel

may

cau

se si

de e

ffect

s inc

ludi

ng h

eada

che,

diz

zine

ss, s

tom

ach

pain

, na

usea

, fev

er, i

tchi

ng, h

ives

(esp

ecia

lly se

rious

). ht

tp://

ww

w.n

cbi.n

lm.n

ih.g

ov/p

ubm

edhe

alth

/PM

H00

0047

4/ht

tp://

ww

w.rx

list.c

om/b

iltric

ide-

drug

/pat

ient

-imag

es-s

ide-

effe

cts.h

tm

90.

Pred

niso

ne

Hum

an a

nd h

orse

ster

oid

21 U

SC §

522

.189

0 -

Hor

ses,

dogs

and

cat

s -

“Not

for u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

Ster

oids

shou

ld b

e ta

ken

unde

r a d

octo

r’s su

perv

ision

and

hav

e m

ultip

le si

gnifi

cant

ad

vers

e af

fect

s inc

ludi

ng se

vere

alle

rgic

reac

tions

, hor

mon

al c

hang

es, c

hang

es in

m

enstr

ual f

unct

ions

, men

tal a

nd m

ood

chan

ges,

resp

irato

ry p

robl

ems,

naus

ea a

nd

vom

iting

, joi

nt sw

ellin

g, v

ision

cha

nges

, and

unu

sual

wei

ght g

ain.

91.

Pros

tagl

andi

n Lu

taly

se so

lutio

n H

orse

and

hum

an u

se –

regu

latio

n of

C

an c

ause

unk

now

n an

d un

wan

ted

horm

onal

effe

cts,

incl

udin

g te

rmin

atio

n of

pr

egna

ncy,

to in

divi

dual

s who

inge

st w

ithou

t kno

win

g.

25

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

fem

ale

repr

oduc

tion

and

othe

r use

s. Th

is dr

ug is

not

to b

e ad

min

ister

ed to

ho

rses

that

are

to b

e sla

ught

ered

for

use

in fo

od.

http

://w

ww

.dru

gs.c

om/v

et/lu

taly

se-

steril

e-so

lutio

n-ca

n.ht

ml

92.

Pseu

doep

hedr

ine

HC

l Tr

i-Hist

Gra

nule

s N

ot fo

r use

in h

orse

s int

ende

d fo

r fo

od.

http

://w

ww

.dru

gs.c

om/v

et/tr

i-hist

-gr

anul

es.h

tml

Can

cau

se c

entra

l ner

vous

stim

ulat

ion,

inso

mni

a, a

nxie

ty, d

izzi

ness

, blu

rred

visio

n,

colit

is, a

nd p

sych

osis

whe

n co

mbi

ned

with

oth

er d

rugs

.

93.

Pyra

ntel

Pam

oate

Ex

odus

Pas

te

Dew

orm

er

21 C

FR §

520

.204

4 -

Hor

ses a

nd p

onie

s -

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

21 C

FR §

520

.204

3 -

Hor

ses a

nd p

onie

s -

“Do

not u

se in

hor

ses i

nten

ded

for h

uman

con

sum

ptio

n.”

http

://w

ww

.dru

gs.c

om/v

et/e

xodu

s-pa

ste.h

tml

Adv

erse

reac

tions

incl

ude

abdo

min

al c

ram

ps, n

ause

a an

d vo

miti

ng, d

iarrh

ea,

head

ache

, diz

zine

ss.

http

://w

ww

.pdr

.net

/dru

gpag

es/c

onci

sem

onog

raph

.asp

x?co

ncise

=298

5

94.

Pyri

doxi

ne H

Cl

Live

r 7 in

ject

ion

Pote

ntia

l hea

lth e

ffect

s afte

r ing

estio

n un

know

n.

http

://w

ww

.scie

ncel

ab.c

om/m

sds.p

hp?m

sdsI

d=99

2476

595

.Py

rila

min

e M

alea

te U

SP

Tri-H

ist G

ranu

les

Ant

ihist

amin

e (h

uman

and

hor

se u

se)

21 C

FR §

522

.206

3 -

“Do

not u

se in

hor

ses i

nten

ded

for f

ood

purp

oses

.”

Not

for u

se in

hor

ses i

nten

ded

for

food

.ht

tp://

ww

w.d

rugs

.com

/vet

/tri-h

ist-

gran

ules

.htm

l

Man

y in

divi

dual

s with

iden

tifie

d he

alth

con

ditio

ns h

ave

hype

rsen

sitiv

ities

to

antih

istam

ines

and

the

use

of a

ntih

istam

ines

is c

ontra

indi

cate

d in

that

por

tion

of th

e po

pula

tion.

ht

tp://

ww

w.d

rugs

.com

/pro

/pol

y-hi

st-pd

.htm

l

26

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

96.

Rab

ies v

acci

natio

n Im

ovax

Rab

ies V

acci

ne

The

dang

ers o

f hum

an in

gesti

on a

re u

nkno

wn.

97

.R

acto

pam

ine

hydr

ochl

orid

eO

ptaf

lexx

100

Pre

mix

B

eta-

agon

ist u

sed

for g

row

th

prom

otio

n pu

rpos

es

A Ja

nuar

y 20

12 a

rticl

e re

porte

d th

at ra

ctop

amin

e hy

droc

hlor

ide

is “[

f]ed

to a

n es

timat

ed 6

0 to

80

perc

ent o

f pig

s in

the

Uni

ted

Stat

es, [

and

has]

has

sick

ened

or

kille

d m

ore

of th

em th

an a

ny o

ther

live

stock

dru

g on

the

mar

ket.”

W

hile

the

FDA

ha

s app

rove

d th

e dr

ug fo

r use

in c

ows a

nd p

igs,

man

y co

untri

es h

ave

bann

ed it

from

fo

od-p

rodu

cing

ani

mal

s, an

d th

e dr

ug h

as n

ever

bee

n te

sted

on h

orse

s int

ende

d fo

r hu

man

con

sum

ptio

n.

http

://bo

ttom

line.

msn

bc.m

sn.c

om/_

new

s/201

2/01

/25/

1022

0221

-disp

ute-

over

-dru

g-in

-fe

ed-li

miti

ng-u

s-m

eat-e

xpor

ts98

.R

hino

pneu

mon

itis

vacc

ine

5-w

ay (v

acci

natio

n)

http

://w

ww

.alp

inea

nim

al.n

et/p

age6

263

a3c5

.htm

l?in

c=na

Unk

now

n co

nseq

uenc

es fo

r hum

ans.

99.

Ron

idaz

ole

A

ntip

roto

zoal

age

nt

http

://w

ww

.wed

gew

oodp

etrx

.com

/ite

ms/r

onid

azol

e-ca

psul

e.ht

ml

Doe

s not

app

ear t

o ha

ve a

ny h

uman

app

licat

ions

. D

ange

rous

side

effe

cts i

n an

imal

s.

Toxi

city

info

rmat

ion

and

pote

ntia

l hea

lth e

ffect

s are

unk

now

n.

http

s://w

ww

.reag

entw

orld

.com

/pro

duct

s/msd

s2.a

sp?p

roid

_2=2

3072

100.

Sele

nium

Tr

ace

min

eral

supp

lem

ent

21 U

SC §

522

.210

0 -

“Do

not u

se in

hor

ses i

nten

ded

for f

ood.

Rar

e bu

t pot

entia

l sid

e ef

fect

s inc

lude

nau

sea,

vom

iting

, abd

omin

al p

ain,

hea

ring

loss

, fa

tigue

, wei

ght l

oss,

mus

cle

tend

erne

ss, h

eart

failu

re, a

nd a

llerg

ic re

actio

ns.

101.

Stan

ozol

ol

Ana

bolic

ster

oid

Use

d in

bot

h an

imal

s and

hum

ans.

21 U

SC 5

22.2

150

- “N

ot fo

r use

in h

orse

s int

ende

d fo

r foo

d.”

http

://w

ww

.pet

plac

e.co

m/d

rug-

libra

ry/st

anoz

olol

-w

instr

ol/p

age1

.asp

x

Pote

ntia

l sid

e ef

fect

s of a

nabo

lic st

eroi

ds a

re w

ell-d

ocum

ente

d. S

tero

ids s

houl

d be

ta

ken

unde

r a d

octo

r’s su

perv

ision

and

hav

e m

ultip

le si

gnifi

cant

adv

erse

affe

cts

incl

udin

g se

vere

alle

rgic

reac

tions

, hor

mon

al c

hang

es, c

hang

es in

men

strua

l fu

nctio

ns, m

enta

l and

moo

d ch

ange

s, re

spira

tory

pro

blem

s, na

usea

and

vom

iting

, joi

nt

swel

ling,

visi

on c

hang

es, a

nd u

nusu

al w

eigh

t gai

n

102.

Stilb

enes

U

sed

in e

strog

en-re

late

d su

bsta

nces

A

nim

als t

reat

ed w

ith th

ese

drug

s are

ban

ned

from

mea

t pro

duct

ion

in th

e Eu

rope

an

Uni

on.

http

://eu

r-le

x.eu

ropa

.eu/

smar

tapi

/cgi

/sga_

doc?

smar

tapi

!cel

expl

us!p

rod!

CEL

EXnu

mdo

c&lg

=EN

&nu

mdo

c=32

008L

0097

103.

Stra

ngle

svac

cine

(S

trep

toco

ccus

Equ

i va

ccin

e)

Vac

cina

tion

for s

trept

ococ

cus e

qui

http

://w

ww

.aae

p.or

g/str

angl

es.h

tmPi

nnac

le I.

N. (

stran

gles

)

Dan

gers

of h

uman

inge

stion

unk

now

n.

27

Dru

gPr

oduc

t/Typ

e/W

arni

ngs

Pote

ntia

l pro

blem

s fro

m h

uman

inge

stio

n of

res

idue

or

met

abol

ites

http

://w

ww

.dru

gs.c

om/v

et/p

inna

cle-

i-n.h

tml

104.

Sucr

alfa

te

Use

d to

aid

in h

ealin

g ga

stroi

ntes

tinal

trac

t, ul

cers

, for

hu

man

s and

ani

mal

s.

Adv

erse

reac

tions

incl

ude

cons

tipat

ion,

dia

rrhea

, nau

sea

and

vom

iting

, pru

ritus

, ras

h,

dizz

ines

s, in

som

nia,

bac

k pa

in, h

eada

che,

dry

mou

th, f

latu

lenc

e, g

astri

c di

scom

fort,

in

dige

stion

, sle

epin

ess.

http

://w

ww

.pdr

.net

/sear

ch/se

arch

Res

ult.a

spx?

sear

chC

riter

ia=S

ucra

lfate

105.

Sulfa

diaz

ine

Trib

risse

n (o

ral)

400

paste

21

CFR

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nase

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us b

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elez

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ills L

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ide,

J.E M

ERG

.MED

. 30(

4):4

07-1

0 (2

006)

.

EXHIBIT 2

EXHIBIT 3

EXHIBIT 4

EXHIBIT 5

EXHIBIT 6

EXHIBIT 7

EXHIBIT 8

EXHIBIT 9

EXHIBIT 10

EXHIBIT 11

EXHIBIT 12

EXHIBIT 13

EXHIBIT 14

EXHIBIT 15

EXHIBIT 16

1

2

Canadian Horse Defence Coalition 150 First Street P.O. Box 21079 Orangeville, Ontario L9W 4S7 Phone: (250) 768-4803 Email: [email protected]: www.defendhorsescanada.org

CONTENTS

Executive Summary 3

Investigation Findings 9

Violations of Canadian Laws: Meat Inspection Act – Part III 25

Audit Results 26

Slaughter Footage Index:

July 13, 2011 29

July 14, 2011 60

Appendix A: The Meat Inspection Regulations, 1990 - Part III 66

Appendix B CFIA Manual of Procedures, Chapter 17, Annex E 68

CFIA Equine Information Document (EID) – Template 69

Appendix C CFIA List of Federally Registered Horsemeat Establishments 70

Appendix D: Equine Anatomy 72

Appendix E: Photographs of horses in overnight holding pens 73

Appendix F: Samples of EID Photos and Forms 77

Appendix G: Stun box design 82

Appendix H: Photographs of discarded halters, cold storage and hides 84

Cover Image: Horse 19 from Day 2 in stun box at Les Viandes de la Petite-Nation Inc. St-André-Avellin, Quebec

EXECUTIVE SUMMARY

Les Viandes de la Petite-Nation Inc. is a private meat processing company that slaughters a variety of species, including horses. In 2010, the company received a $2.0 million infusion from the federal government to help with upgrades to its meat processing facility: http://www.meattradenewsdaily.co.uk/news/061010/canada___more_government_meat_investment_.aspx.

Further, in March 2011, a repayable loan of $2.0 million was granted by Agriculture and Agri-Food Canada for the purpose of improving and modernizing slaughter operations and enhancing slaughter capacity in the plant: http://www4.agr.gc.ca/AAFC-AAC/display-afficher.do?id=1306532429398&lang=eng.

The CHDC was provided with full footage from two days and numerous photos taken by an anonymous source at Les Viandes de la Petite-Nation on July 13 and 14, 2011.

Les Viandes de la Petite-Nation differs from other horse slaughterhouses from which we have received slaughter footage (Natural Valley Farms/Natural Meat Company, Bouvry Exports and Viande Richelieu) in that some of the workers, and the shooter in particular, seem to have been provided with training on horse behaviour (the man possibly whipping horses into the kill line, however, was an exception, as he could frequently be heard yelling at and whipping the horses down the kill line).

Regarding the improved handling practices, an article in Alberta Farm Express dated September 26, 2010 entitled “Que. multi-species meat plant gets loan for renos”, stated:

“The company notes its three-year-old plant includes the ‘most modern’ animal handling systems in Canada, designed by the U.S. livestock handling expert Temple Grandin.” “‘Total respect and consideration are given to the animals in order to minimize stress,’ the company states on its website.”: http://www.albertafarmexpress.ca/news/que-multi-species-meat-plant-gets-loan-for-renos/1000386850/

This photo shows overcrowded horses in the holding pens at Les Viandes de la Petite-Nation with the trademark Temple Grandin designed walkway for cattle to the left.

3

4

While the shooter sometimes made an effort to calm the frantic horses in the stun box, the vast majority continued to be terrified. These attempts to calm the horses did not help to ensure a humane death. In fact, Les Viandes de la Petite-Nation has the highest failure to stun rate of all the plants we have audited.

On Day 1, fully 59% of the horses had to be shot more than once (with one horse receiving up to 11 shots). An additional 10% should have been afforded at least a second shot, but were not.

On Day 2, 28% were shot more than once, with an additional 7 requiring a second shot, but never receiving it (even though the shooter may have felt that additional shots were required, and attempted to do so, but it appeared that the captive bolt pistol jammed).

This is a clear indication that good management cannot compensate for the many factors that contribute to making horse slaughter in an assembly-line manner inherently inhumane.

Canada’s Meat Inspection Act - PART III (Appendix A) states: Examination, Inspection, Humane Treatment and Slaughter, Packaging and Labeling 79. Every food animal that is slaughtered shall, before being bled,

(a) be rendered unconscious in a manner that ensures that it does not regain consciousness before death, by one of the following methods:(i) by delivering a blow to the head by means of a penetrating or non-penetrating mechanical device in a manner that causes immediate loss of consciousness, http://laws-lois.justice.gc.ca/eng/regulations/SOR-90-288/page-20.html

As for government oversight, even after the Canadian Horse Defence Coalition (CHDC) had exposed 3 other horse slaughterhouses and the many significant welfare problems within them, the Canadian Food Inspection Agency (CFIA) officials were again conspicuously absent at La Petite-Nation.

In some 20 hours of footage over a span of 2 days, just one inspector or veterinarian (white hard hat, blue smock and stethoscope worn around neck) appeared at the stun box, overseeing the stunning of 3 to 5 horses for a total of only 3½ minutes. He was present for just 1 minute, 11 seconds on Day 2, but no horse was in the stun box at the time.

It is also very likely that a number of horses revived on the suspending line, given that a blood-covered captive bolt pistol was carried in from the suspending/butchering area to the stun box area to be hosed off. The amount of blood on the pistol leads us and our veterinarian auditor to believe that it must have been used on horses that were already bleeding out from the shots applied in the stun box. This would give the plant an Automatic Fail - the same rating Natural Valley Farms/Natural Meat Company (now defunct), Bouvry Exports and Viande Richelieu all received.

The sheer terror of the horses was evident in the number of individual animals who whinnied, slipped, and fell in the stun box (including those who even whinnied after receiving one or more shots: Horses 41 and 54 on Day 2). This would also give the plant a fail rating on the slaughter audit standards.

5

The poor design of the stun box with its plastic curtain separating it from the suspending/butchering area added to the horses’ fear. Many horses parted the curtain with their noses to stare into the suspending/butchering area. One horse stared into the butchering area for over 20 seconds and a number of horses were shot while staring into the area, thus resulting in an incorrect angle for the shot.

While the shooter appeared to be diligent in hosing the front of the stun box where he could see blood and brain matter, not once was the stun box hosed thoroughly on the inside, where the majority of matter accumulated. As soon as a horse entered the stun box they were met with dripping blood, brain matter and excrement from those who went before them.

In addition, the time between horses entering the stun box after the horse before them was alarmingly short, with an average of less than 3 minutes (see tables beginning on page 21).

Adding further stress to the horses, but which seems to be common practice in slaughter plants, was they were not provided with hay or water in the overnight holding pens. Many of these horses were thin and dehydrated, and some in a weakened state. From the Equine Information Documents (EIDs) photographed, we know that many of the horses came from the U.S., from States as far away as Tennessee. EID evidence indicates the horses were purchased at Sugarcreek, Ohio; Shipshewana, Indiana; and Ontario Livestock Exchange (OLEX) horse auctions.

One horse on the night of the walk-through, as seen in the evidence provided, appeared sick, diseased or injured and was lying down, putting him at risk of being trampled by the others. If this horse was in this condition upon arrival, the CFIA officials and/or workers at the plant should have segregated or euthanized him, as humane slaughter regulations require.

Since January 2010, it is mandatory for all operators of CFIA inspected facilities in Canada engaged in equine slaughter for edible purposes to have complete identity and medical records for all animals (domestic and imported) presented for slaughter. These records are referred to as Equine Information Documents (EIDs).

CFIA Manual of Procedures, Chapter 17, Annex E sections include: EID Elements; List of Veterinary Drugs Not Permitted for Use in Equines Slaughtered for Food; List of “Essential Veterinary Drugs Permitted in Equines with a 6-Month Withdraw Period”, and other sections of information meant to inform how the CFIA intends to meet European Commission requirements for horsemeat exports (Appendix B): http://www.inspection.gc.ca/english/fssa/meavia/man/ch17/annexee.shtml

The EID forms at La Petite-Nation uniformly denied any drugs given to the horses, including animals as old as 30 years who had clearly not been with the same owner for the extent of their lives. It is a well-known fact that aged horses may exchange hands numerous times. Also, there is a possibility that the required 6-month quarantine time for some horses would contribute to sick equines becoming sicker and more infectious. This was evidenced in the footage, as 6 horses appeared to have serious eye infections that went untreated.

Upon our review, the 63 EIDs examined received a complete fail grade. All have some form of omission, ranging from incomplete owners' or agents' information to the disturbing discovery of some horses whose descriptions do not match their pictures. From a food traceability standpoint, we found these results alarming.

After reviewing all the EIDs it is apparent that some auction houses are helping to complete the documents on behalf of some owners or agents. Consistent statements such as "Drug-free Six Months" in the same hand writing, and the same red pen colour, are written across the top.

In the case of one Agent, a stamp is repeatedly used. The use of a stamp to fill in a government mandated document for the purposes of food safety, at the very least, sets a frightening precedent. The government's directive is “Signature of Agent” not “Signature of Agent or a reasonable facsimile”.

The sloppiness and inaccuracy in how these EIDs are filled out, and the nonchalance in how they are accepted by slaughterhouses that are federally sanctioned in Canada to examine and oversee them, is appalling.

The EID should be treated as a stand-alone document for traceability records; all information relating to that horse should be detailed on them and should be legible, complete and correct. All pictures should be clear and securely attached. None of this has been done in the sampling we've investigated.

Also noted on the EID form is a declaration that the owner signs stating: “I always treated the animal with respect and care to meet the needs.” The reality for some horses can be quite different from this statement, such as this mare, Horse # 31.

6

We note that some EIDs are pre-printed with the name “Richelieu Meat” in the top right corner. Since this government-based form carries an industry header, one could be led to believe that the CFIA and the slaughter industry are actually quite closely aligned. Also, this form is being used at La Petite-Nation, not Richelieu Meats.

Of interest is the fact that the European Commission (EC), seriously concerned about the potential presence of phenylbutazone in horsemeat, is not permitting horses over the age of 6 months to enter the food chain.

The Irish Veterinary Journal, Volume 63, Number 12: http://www.veterinaryirelandjournal.com/Links/PDFs/CE-Large/CELA_Dec_2010.pdf.pdfstates: “The legislation is now in place (EU Commission Reg. No 504/2008), stating that all horses in Europe must have an equine passport. The legislation goes further to state that any passport issued to an equine over six months of age will automatically be excluded from the food chain.”

In view of these and other stringent regulations on European soil, the CHDC questions why the EC places its consumers at risk by allowing potentially tainted horse meat from Canada to end up on dinner plates in Europe.

As this report clearly proves, Canada has a faulty EID system that invites fraud and permits horses of any age to enter the slaughter pipeline, which confirms that the EID system is far from a guarantee that food safety is being addressed.

The evidence also clearly shows that it is impossible, even in a modern designed facility, to humanely slaughter horses in an assembly-line manner.

The CHDC has previously been in receipt of footage from 3 Canadian slaughterhouses killing horses. The previous 3 were from the 2010 investigations of Bouvry Exports and Viande Richelieu, as well as the 2008 investigation of Natural Valley Farms/Natural Meat Company.

7

8

After those investigations were released publicly, and despite reassurances from the CFIA and industry that conditions would be improved, this recent investigation demonstrates that a fourth Canadian slaughterhouse is again in violation of humane slaughter regulations.

Based on the evidence and audit failure rating, the CHDC calls on the CFIA and the Canadian government to immediately close Les Viandes de la Petite-Nation slaughter plant and adopt Bill C-322, an Act which will ban the slaughter of horses as well as the importing and exporting of horses to slaughter in Canada: http://www.parl.gc.ca/HousePublications/Publication.aspx?Language=E&Mode=1&DocId=5159966&File=24.

We conclude that horse slaughter must be ended in Canada and all equine slaughterhouses closed.

9

INVESTIGATION FINDINGS

The CHDC was provided with footage and photos taken by an anonymous source at Les Viandes de la Petite-Nation on July 13 and 14, 2011. The raw images and footage can be made available for review.

Fear Inducing Environment - NoiseNoise levels are high in the plant from the machinery, compressors and saws. As horses rely on sound as their second most important sense, this is very likely distressing for them. It also seems likely that the noise presents both a risk to the workers' hearing and poses a hazard to being able to hear important messages between workers.

It has also been shown that the body's reaction to noise is similar to its response when under stress. Blood pressure and heart rates can increase and hormone and blood cholesterol levels can change. Exposure to too much noise can make a person feel tired, posing an additional safety hazard to both the workers and horses.

Horses' ResponseThe horses appeared fearful in this environment and vocalizing was present. Vocalizing was prevalent throughout both days but more frequent on Day 2. Many horses whinnied multiple times, some even after being shot (Horses 41 and 54 on Day 2). 10% and 17% of the horses vocalized over the 2 days respectively, earning the plant a fail on the American Meat Institute's humane audit standards (designed by Dr. Temple Grandin).

Also, a common behaviour for the horses in the stun box was extreme shaking from fear. Twitching and flinching was also common. Instances of slipping and losing their footing were also seen.

As each day progressed and the stun box became more covered in blood, the horses became more resistant to enter it, so had to be forced from behind with the use of what appeared to be a whip (footage shows a whip as the primary driving tool with plastic paddles also used in the stun box).

Lack of Food and Water in Holding PensThe lack of basic provisions such as food and water are illegal according to the Meat Inspection Act. Given the dehydrated and thin state of many of the horses, as well as the long duration of their transport, the provision of water is a requirement. EIDs show the majority of horses came from U.S. States as far away as Indiana, Pennsylvania, Ohio, New York, Michigan, West Virginia and Tennessee. Not providing water at the slaughter plant shows a total disregard for the welfare of these already stressed and suffering horses.

Condition of the HorsesAt least 6 horses appeared to have some form of eye injury or infection in the slaughter footage. One horse appeared to have a large tumour in his/her left eye (Horse 29 - Day 2. See photo in Footage Index).

Many of the horses seen during the walk-through photos of the plant were very thin and likely dehydrated (Appendix E). Photos of other horses attached to EID forms also show thin horses (Appendix F).

Several horses in the holding pens appeared to be Thoroughbreds. One very thin chestnut with tag # 9382 (pictured below) had saddle pad sweat marks on his back, indicating that he had been ridden (perhaps even raced) shortly before shipping to slaughter.

Another, seen in the next image, had what appeared to be rub marks from an ill-fitting harness crupper. This horse also had a shaved bridle path, which is very common in Standardbreds to keep the “check rein” from tangling in the mane.

Some of the horses in the slaughter footage were slick with sweat or had dried sweat marks, indicating a high level of stress or that the holding area was not temperature controlled.

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One horse documented during the walk-through appeared too sick, diseased or injured to stand. If this was the condition of the horse when it arrived, he or she should have been euthanized or segregated as is required by the CFIA: http://www.inspection.gc.ca/english/anima/trans/transpoe.shtml.

Some of the horses documented during the walk-through and in the slaughter footage also had additional USDA kill-only and auction stickers on them. One horse had 4 stickers indicating that he or she was likely put through the trauma of multiple auctions and multiple transports.

A total of 104 horses and mules were slaughtered on Day 1. A further 60 were slaughtered on Day 2.

A large number of horses were “light boned” with partially shaved manes at the bridle path. This is a common practice for racing Standardbreds, horses used in harness to pull carriages, as well as Thoroughbreds, show and pleasure horses. Among the many horses slaughtered were Thoroughbred and Standardbred racing stock.

Faulty DocumentationOne registered Standardbred was a 4-year-old mare named “Spill the Ink”, a descendant of Cam Fella. She raced as recently as April 8, 2011, only 3 months before being slaughtered.

Spill The Ink’s EID has some of the worst omissions of all the 63 EIDs we reviewed. The owner's address was incomplete. No age was specified. The required Primary Location was not filled in, nor was the Primary Use of Animal checked. As she last raced on April 8, 2011, her registered owner is not the name written on the EID. The EID also states that this person had “uninterrupted possession, care or control of the animal" from January 1, 2011 to July 7, 2011, illustrating how poor recording practices are with regard to the EIDs examined. Despite receiving faulty documentation, they are accepted regardless by slaughterhouse personnel and the CFIA.

Note that her EID does not show her age, plus the owner’s address is incomplete.

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Horse Breed NotesThere were a wide variety of breeds, including a number of mules. Below is a sampling of the breeds:

Breed Quantity

Belgian 21 (15%)

Standardbreds (suspected) 15

Paints 10

Percherons 7

Mules 6

Draft Crosses 5

Appaloosas 2

Transport to QuebecLes Viandes de la Petite-Nation is located in St. Andre-Avellin, Quebec. EID evidence indicates the horses in this report were purchased primarily from 3 auctions:

Shipshewana Auction - Shipshewana, Indiana 1200 kilometers from La Petite-Nation Over 13.5 hours transport time

Sugarcreek Auction - Sugarcreek, Ohio 1050 kilometers from La Petite-Nation Over 12 hours transport time

Ontario Livestock Exchange (OLEX) - St. Jacobs, Ontario 645 kilometers from La Petite-Nation Over 8 hours transport time

It's probable that many horses were transported over a number of days, and many may not have been afforded food and water during that time. Not surprisingly, a great number of horses in this report appear thin and dehydrated, as their final days consist of shipment to auction, then auction to holding pen, to long distance transport in crowded trailers, to overnight holding in the slaughter plant without food or water.

Improperly Designed Stun BoxThe stun box was seen to have many deficiencies.

Most notably, the stun box is too small for the large draft horses that are common here.The Belgian in this image completely fills this small space. Like most of the other large drafts, he hit his head on the stanchion coming in to the box.

Also concerning for horses is the layout of the entrance into the stun box. They have to step down into it, as opposed to walking on a level surface from the kill line into the box. This is unsettling for the horses that are already in a frightened state.

Once in the box, the floor is slanted towards the dismembering room to allow gravity to cause the body to slide into the bleed out area.

The next image shows the step down, as well as the slanted floor.

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The box and the shooter are on the same level, which means that the shooter must reach well above the heads of most of the horses to hit them with the captive bolt pistol, but in the majority of the time, this does not allow for the proper angle to be achieved.

In this image, this example being common practice, the shooter leans far over the horse’s head to try to hit a moving target, making an accurate hit very difficult.

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Most disturbing is that many of the horses were able to push their heads out the front of the stun box and peer into the butchering area where the horses before them were being hung, bled out and butchered. Many horses appeared increasingly agitated and frightened after doing so.

The image below shows Horse # 27 from Day 2 looking into the dismemberment area.

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The image below is from the front of the stun box. The long plastic curtain hangs on the left where horses can look through to the dismemberment room. A short plastic curtain lines the side of the box that opens from the bottom to allow the horses’ bodies to slide through into the dismemberment area.

Looking from this view, the area to the immediate right of the box is higher than where the shooter would stand. This makes no sense as reason would dictate that the shooter should be higher than the horses, not lower. The higher level platform on the right was used by an inspector to view slaughter proceedings a few times.

Most horses were head shy and some were also hesitant to lift their heads. With these animals the shooter used a flat plastic paddle to lift up their heads.

The drover who herded the horses to the stun box from the kill line used a whip to get the horses into the box. The whip was heard often and seen several times.

Many horses trembled very badly in the stun box and lost their footing repeatedly. Also, the floor of the box appears to be slanted, which may also partially explain why so many horses lost their footing in the box. Another factor is likely the accumulation of waste and blood from all the horses that went through previously.

In the next two pictures, the left side at the horses' eye level is completely open, which allows them to look through it easily, as this Percheron and Chestnut horse were able to do.

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17

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Improper StunsIn total, 51 to 61 of 104 horses appeared to not have been rendered unconscious after the first shot on the first day; 17 to 24 of 60 horses on the second day. The shooters frequently made second and third shots, however, many of these appeared to be inaccurately placed.

Many of the shots appeared to have been placed far too high on the horses' heads (on the poll) or too low (between the horses’ eyes). When the shooter would deliver a second, third, or fourth shot he would often do so to the far right or far left of the original shot. If the horse continued moving after this, the shooter would then "pith" the horse by shooting him or her at the base of the brain (at the poll). This is known to immobilize the animal but does not render it unconscious: http://www.fao.org/DOCREP/004/Y0660E/Y0660E01.htm.

“Pithing unstunned animals is not an acceptable method of destruction as it is inhumane. It is essential on animals that have been stunned only, for example when captive-bolts are used on larger animals. Pithing is also a safety measure to prevent workers being struck by the involuntary movements of a stunned animal.”

The retracting bolt of the captive bolt pistol also appeared to become jammed in the heads of a number of horses or perhaps did not emerge at all, leading to horses being hit repeatedly and growing increasingly frantic with each failed hit.

As mentioned above, the angle of numerous shots appeared to be incorrect. According to the CFIA’s own instruction manual “Meat Hygiene Directive” (below) the angle of the shot should be from above, directed downwards and at an angle towards the spine of the horse. The positioning at La Petite-Nation, however, appeared incorrect, with the shooter standing lower than the horses' heads. This is especially disastrous for the draft horses.

Chapter 12, Page 22 - Food Animal Handling and Slaughter – Animal Welfare Requirements: http://www.inspection.gc.ca/english/fssa/meavia/man/ch12/annexae.pdf

Also according to the diagram, the shot should be just above the point of intersection of an X drawn diagonally from each eye to each opposite ear. Yet, many of the shots delivered appeared consistently too high or too low on the horses’ heads. Numerous second and third shots were either to the left or right of these initial shots and also appeared too high.

The photo below of Horse 40 shot on July 13, 2011 clearly shows where the first shot hit the horse towards the right and the other hole is from the second shot.

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The shooter had ample opportunity to correctly place the captive bolt pistol in this instance as the photo below here shows that the horse was in a good position to be shot correctly.

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It was also concerning that the shooters would frequently pound hard on the horses’ heads with the captive bolt pistol, instead of placing it against the target area, which caused unnecessary fear and suffering to the horses in the moments before being stunned.

As noted above, there were, on occasion, two shooters. The primary shooter appeared to have had some training in working around horses and worked in a reasonably calm manner. The other shooter, whose primary job was to herd the horses into the stun box, appeared to be rough in his handling practices.

In summary, the many systemic problems at Viandes de la Petite-Nation resulted in terrifying, painful deaths for the majority of the horses documented, with over two-thirds being so frightened that their knees buckled, trembled badly and lost their footing, pawed, thrashed about or attempted to jump from the stun box.

Approximately 40% of the horses, having experienced the excruciating pain of a bolt piercing their faces and brains, remained standing, whinnying or flinching away from the shooter, when and if a second shot was delivered. One horse appeared to have received up to 11 stunning attempts over the course of 3½ minutes (Horse 33, Day 1).

Contributing to the inaccuracy of the stunning process is the assembly-line speed at which horses are moved from the stun box to the bleed-out room. The chart below illustrates just how little time elapses between one horse entering the stun box to the next horse going in.

The average time is approximately 3 minutes for a horse to be shot and then passed through to the bleed-out room. The larger gaps in time indicate breaks when no horse was in the stun box.

With speed being the driving factor, it is not surprising that the stun box is not cleaned out properly between horses entering it, and that the assembly-line slaughter of horses results in numerous inaccurate shots with unnecessary suffering.

Day 1 Day 2

Horse # Video Time horse enters stun

box Horse # Video

Time horse enters stun

box

1 11074938 16:13 1 11074922 10:492 11074938 17:32 2 11074922 14:133 11074938 19:14 3 11074922 17:184 11074938 22:37 4 11074922 18:555 11074938 24:07 5 11074922 20:446 11074938 25:40 6 11074922 22:477 11074938 28:41 7 11074922 24:218 11074938 30:18 8 11074922 25:459 11074938 34:11 9 11074922 28:11

10 11082608 00:38 10 11074922 29:5911 11082608 03:35 11 11074922 31:5412 11082608 05:00 12 11074922 34:3213 11082608 06:50 13 11082557 00:06

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Day 1 Day 2Horse # Video

Time horse enters stun

boxHorse # Video

Time horse enters stun

box14 11082608 09:38 14 11082557 03:3615 11082608 11:51 15 11082557 05:3016 11082608 14:10 16 11082557 07:1517 11082608 15:49 17 11082557 09:1418 11082608 18:50 18 11082557 12:0919 11082608 19:55 19 11082557 14:5020 11082608 23:33 20 11082557 17:4721 11082608 25:46 21 11082557 20:1122 11082608 27:52 22 11082557 22:4623 11082608 29:15 23 11082557 24:4624 11082608 34:12 24 11082557 26:3325 11090239 04:04 25 11082557 29:1426 11090239 06:24 26 11082557 31:5027 11090239 09:41 27 11082557 36:1728 11090239 14:37 28 11090227 02:0929 11090239 17:08 29 11090227 03:4330 11090239 18:36 30 11090227 12:1031 11090239 21:14 31 11090227 14:5532 11090239 23:25 32 11090227 17:1633 11090239 25:28 33 11090227 19:5534 11090239 29:11 34 11090227 21:3635 11090239 32:59 35 11090227 23:3036 11090239 34:55 36 11090227 25:1637 11093915 00:17 37 11090227 28:1138 11093915 04:24 38 11090227 31:2339 11093915 33:21 39 11090227 34:4540 11101547 00:35 40 11090227 36:0441 11101547 02:50 41 11093857 00:5842 11101547 05:24 42 11093857 03:1543 11101547 07:37 43 11093857 33:0044 11101547 09:39 44 11093857 34:3345 11101547 22:13 45 11093857 36:2046 11101547 23:56 46 11101527 01:4547 11105218 07:35 47 11101527 03:0748 11105218 09:09 48 11101527 04:2949 11105218 10:58 49 11101527 06:3250 11105218 14:09 50 11101527 08:0851 11105218 15:51 51 11101527 09:1652 11105218 20:14 52 11101527 11:0253 11105218 22:44 53 11101527 12:3754 11105218 24:18 54 11101527 14:4455 11105218 25:24 55 11101527 16:35

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Day 1 Day 2Horse # Video

Time horse enters stun

boxHorse # Video

Time horse enters stun

box56 11105218 26:36 56 11101527 18:5057 11105218 28:39 57 11101527 21:1658 11105218 33:00 58 11101527 22:5259 11112847 00:26 59 11101527 26:4160 11112847 12:09 60 11101527 28:3061 11112847 15:3962 11120517 30:1963 11120517 34:3564 11124148 00:1065 11124148 01:5866 11124148 05:2767 11124148 06:5568 11124148 10:0269 11124148 12:0370 11124148 13:5071 11124148 16:4572 11124148 32:1973 11124148 33:4974 11124148 35:2875 11131817 34:3076 11135447 00:1977 11135447 02:0578 11135447 03:1079 11135447 05:0780 11135447 06:4081 11135447 07:4682 11135447 09:3283 11135447 11:5684 11135447 13:3485 11135447 16:5786 11135447 18:1387 11135447 19:4088 11135447 21:0689 11143118 09:0890 11143118 11:2991 11143118 13:1392 11143118 14:5093 11143118 18:1394 11143118 19:2795 11143118 21:05

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Day 1 Horse # Video

Time horse enters stun

box 96 11143118 22:5197 11143118 25:0598 11143118 26:3399 11143118 28:20100 11143118 33:10101 11143118 35:49102 11150747 01:20103 11150747 03:18104 11150747 04:55

Subject to the evidence provided by the footage, we conclude that Viandes de la Petite-Nation should receive a Fail on 3 of 4 Core Criteria on the American Meat Institute Slaughter Audit standards, with a possible Automatic Fail for Bleed-Rail Sensibility.

Based on the evidence and audit failure rating, the CHDC calls on the CFIA and the Canadian government to immediately close Les Viandes de la Petite-Nation slaughter plant and adopt Bill C-322, an Act which will ban the slaughter of horses as well as the importing and exporting of horses to slaughter in Canada: http://www.parl.gc.ca/HousePublications/Publication.aspx?Language=E&Mode=1&DocId=5159966&File=24.

We have done our best at detailing the video in the attached Footage Index. Short compilations of the footage are available on our website at www.defendhorsescanada.org.

For further inquiries please contact the undersigned:

Sinikka Crosland Twyla Francois Executive Director Central Region Director 250.768.4803 204.296.1375 [email protected] [email protected]

Pour un interview en français, contactez Dr. Olivier Berreville – 204.891.8136

Canadian Horse Defence Coalition December, 2011

150 First Street P.O. Box 21079 Orangeville, ON L9W 4S7

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VIOLATIONS OF CANADIAN LAWS

Meat Inspection Act – Part III Examination, Inspection, Humane Treatment and Slaughter, Packaging and Labelling:http://laws-lois.justice.gc.ca/eng/regulations/SOR-90-288/page-20.html

Meat Inspection Act - PART III Examination, Inspection, Humane Treatment and Slaughter, Packaging and Labelling62.(1) No food animal shall be handled in a manner that subjects the animal to avoidable distress or avoidable pain.

63.(2) Every food animal that is obviously diseased or injured shall immediately be segregated from apparently healthy food animals.

64. Every holding pen that is used for food animals awaiting slaughter shall be provided with adequate ventilation and shall not be used in a manner that results in their overcrowding.

65. Every food animal in a holding pen awaiting slaughter shall be provided with access to potable water and shall, if held for more than 24 hours, be provided with feed.

78. No food animal, other than a bird or domesticated rabbit, shall be suspended for the purpose of slaughter unless, immediately before being suspended, it is rendered unconscious or killed by a method set out in section 79.

79. Every food animal that is slaughtered shall, before being bled, (a) be rendered unconscious in a manner that ensures that it does not regain consciousness before death, by one of the following methods: (i) by delivering a blow to the head by means of a penetrating or non-penetrating mechanical device in a manner that causes immediate loss of consciousness.

80. No equipment or instrument for restraining, slaughtering or rendering unconscious any food animal shall be used by any person for those purposes (a) unless the person is, by reason of the person's competence and physical condition, able to do so without subjecting the animal to avoidable distress or avoidable pain; or (b) where the condition of the equipment or instrument or the manner in which or the circumstances under which the equipment or instrument is used might subject the animal to avoidable distress or avoidable pain.

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AUDIT RESULTS

American Meat Institute – Slaughter Audit Forms: http://www.animalhandling.org/ht/a/GetDocumentAction/i/58636

Based on Dr. Temple Grandin/American Meat Institute Audit Date of Killing: Wednesday, July 13, 2011

Core Criteria 1: Effective Stunning 95% accuracy is required for a passing score

Between 49%-59% of horses (of a total of 104) appeared to have been mis-shot and showed clear signs of revival in the form of remaining standing, standing back up, and/or head shaking. (49% were shot two or more times with one horse shot up to 11 times. An additional 10% showed signs of not being rendered unconscious after the first shot, but were not afforded further shots while in the stun box.)

RESULT: FAIL

Core Criteria 2: Bleed Rail Insensibility Any sensible animal on the bleed rail constitutes an automatic audit failure. It is critical that animals showing signs of a return to sensibility be re-stunned immediately.

0% tolerated

While we are not able to see into the suspension/butchering area, the shooter carried a captive bolt pistol out from the area to hose it off as it was covered with blood. This captive bolt pistol was of a different style than the one used in the stun box. We question why the pistol was so blood smeared. Had it been used on horses in the suspension/butchering area who had already sustained at least one shot and had a blood covered face or head?

RESULT: POSSIBLE AUTOMATIC FAIL

Core Criteria 3: Slips and Falls (only Falls counted and only in the stun box) 1% or fewer falls are required for a passing score

While many horses appeared to be terrified in the stun box, lost their footing, thrashed or flailed "only" 4 fell such that their body touched the floor.

RESULT: PASS

Core Criteria 4: Vocalization 3% or less should vocalize (provoked by stress or agitation)

10% of horses vocalized, some as frequently as up to seven times.

RESULT: FAIL

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Based on Dr. Temple Grandin/American Meat Institute Audit Date of Killing: Thursday, July 14, 2011

Core Criteria 1: Effective Stunning 95% accuracy is required for a passing score

Between 28%-40% of horses (of a total of 60) appeared to have been mis-shot and showed clear signs of revival in the form of remaining standing, standing back up, and/or head shaking. (28% were shot two or more times). An additional 7 horses showed signs of not being rendered unconscious after the first shot, but were not afforded further shots while in the stun box. In the case of Horse 30, this was because the captive bolt pistol malfunctioned.

RESULT: FAIL

Core Criteria 2: Bleed Rail Insensibility Any sensible animal on the bleed rail constitutes an automatic audit failure. It is critical that animals showing signs of a return to sensibility be re-stunned immediately.

0% tolerated

While we are not able to see into the suspension/butchering area, the shooter carried a captive bolt pistol out from the area to hose it off as it was covered with blood. This captive bolt pistol was of a different style than the one used in the stun box. We question why the pistol was so blood smeared. Had it been used on horses in the suspension/butchering area who had already sustained at least one shot and had a blood covered face or head?

RESULT: POSSIBLE AUTOMATIC FAIL

Core Criteria 3: Slips and Falls (only Falls counted and only in the stun box) 1% or fewer falls are required for a passing score

While many horses appeared to be terrified in the stun box, lost their footing, thrashed or flailed "only" 1 fell such that their body touched the floor. This horse (Horse 8) fell repeatedly.

RESULT: FAIL

Core Criteria 4: Vocalization 3% or less should vocalize (provoked by stress or agitation)

17% of horses vocalized, some as frequently as up to six times.

RESULT: FAIL

In summary, at least 40% of the horses were not stunned after the first shot and, according to the OIE (World Organisation for Animal Health) based in Europe, under Chapter 7.5 “Slaughter of Animals”, the standards of humane killing of horses are not being met at this facility.

The EU bases their criteria on the OIE standard: http://www.oie.int/international-standard-setting/terrestrial-code/

Slaughter of Animals – Horses, Page 15. http://www.oie.int/fileadmin/Home/eng/Health_standards/tahc/2010/en_chapitre_1.7.5.pdf

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FOOTAGE INDEX LES VIANDES DE LA PETITE-NATION INC.

NOTE:

NUMEROUS FIRST SHOTS APPEARED TO HAVE BEEN INACCURATELY PLACED TOO HIGH ON THE HEAD. MANY SECOND SHOTS APPEARED TO HAVE BEEN AIMED BOTH TOO HIGH AND TOO FAR TO THE RIGHT. MANY THIRD SHOTS APPEARED TO HAVE BEEN AIMED BOTH TOO HIGH AND TOO FAR TO THE LEFT.

ADDITIONAL NOTES:

Camera is located above and to the rear of stun box, angled downward toward the head of the horse in the stun box and the shooter in front of it

Colour Key Red Inaccurate hit, horse remains conscious

Purple Horse shows signs of fear Green Horse slips and falls Blue Horse vocalizing from fear

Brown Horse Shows signs of injury, infection or illness Orange CFIA present

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WEDNESDAY, JULY 13, 2011

VIDEO 11082608

Horse 12 This horse is seen in the video “Pasture to Plate”

04:55 Small bay horse 05:00 Horse sniffs blood left in head stanchion 05:07 Horse attempts to jump out of the stun box, loses footing and falls

05:18 Both the shooter and the man moving the horses into the stun box appear. Shooter says, "Après vous."

In this image the little horse is still trying to regain his footing when the drover reaches in with the captive bolt pistol.

05:20 The drover shoots the horse 05:21 The shooter immediately shoots the horse a second time with a different captive bolt pistol

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Here the horse is shot a second time.

05:42 Side of the stun box is lifted 06:00 Horse is pulled through

VIDEO 1090239

Horse 27 – 12-year-old Belgian stallion, 19HH

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09:40 Large Belgian with halter on tentatively enters still bloody stun box (white auction sticker: 140, green kill-only USDA sticker: 3740) 09:41 Horse sniffs blood in head stanchion while drover can be heard yelling behind horse trying to get him to move ahead 09:50 Horse looks into suspending/butchering area; moves ahead suddenly 10:00 Horse stares into suspending/butchering area 10:08 Halter is removed

10:13 Horse continues to stare into bleed out room 10:20 Horse is shot with captive bolt pistol (audio lag)

10:26 Horse is shot a second time 10:28 Horse lifting head, moving 10:39 Horse is still slightly moving 10:42 More movement of this horse’s head seen 10:51 Horse falls through open side of stun box

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Horse 29 – 10-year-old mare, 16HH EID Primary Location not filled in, EID owner is using phone number of agent

16:54 Nervous, sweaty-looking, probably a Standardbred, thin bay mare with bridle path shaved enters the stun box (white auction sticker: 101, green kill-only USDA sticker: 3746) 17:08 She looks into suspending/butchering area repeatedly 17:31 Shooter has been trying to line up shot saying “whoa, whoa” 17:36 She’s very head shy, swinging head around to avoid shooter 17:38 She’s shot while looking into suspending/butchering area

17:44 Blood can be seen spurting out of the hole when her head falls backwards. She does not appear to be totally unconscious as there is movement of her head as she falls 18:03 Chin lift of stanchion pooling with blood

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Horse 31 – 13-year-old Belgian mare, 19HH Her EID photo shows that she was malnourished, EID does not note 4 white socks, EID Primary Location not filled in, EID owner using phone number of agent.

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21:10 Belgian mare comes into stun box (3 tags – 2 white, 1 green white auction sticker: 290, green kill-only USDA sticker: 3738) Hits her head on top of stanchion 21:14 "HEY! HUP!" can be heard as the drover pushes the horse from behind 21:18 Her mane is twitching

21:21 Can hear a horse whinnying 21:35 She’s head shy, shooter has difficulty aiming 21:38 She’s shot with captive bolt pistol, her body heaves forward and up

21:42 She tries to get back on her feet 21:46 She’s shot a second time into right temple, slowly sinks down, shaking

22:08 She falls through as the side of the stun box is lifted and she slides into bleed out

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Horse 33 – 9-year-old Belgian gelding, 18HH This horse is seen in the video “Pasture to Plate”

EID shows head markings as a blaze not stripe as entered, EID Primary Location not filled in, EID owner is using phone number of agent.

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25:22 Very large Belgian (white auction sticker: 451) 25:28 He is looking into bleed out room but snaps head back as shooter comes through door 25:35 He again looks into suspending/butchering area 25:52 He’s shot, head falls into head stanchion 25:56 Second stunning attempt while head in stanchion 26:05 Third stunning attempt, convulsions appear to be increasing 26:10 Horse's body drops, convulsions increase 26:11 Horse appears to be struggling to regain his footing 26:13 Fourth stunning attempt, just above left eye on the side of his head 26:19 Still reacting to sound 26:29 While attempting to rise, horse receives fifth stunning attempt, into the left temple, head is still up 26:33 Sixth stunning attempt on top at poll; he continues to move 26:40 Seventh stunning attempt on top of head in mane 26:43 Still trying to move, pushing forward, ears are still moving, HORSE IS OBVIOUSLY STILL CONSCIOUS 26:46 Shooter says "Aye - you're not dead" 26:50 Shooter goes into suspending/butchering area Horse is left struggling and conscious 26:53 Horse struggles, pulls ears back and forward, still clearly breathing heavily, body heaving with each breath 26:57 Shooter returns from suspending/butchering area with a different captive bolt pistol, larger 27:01 Eighth stunning attempt with new captive bolt pistol on top of head in his mane 27:04 Ninth stunning attempt into poll with new captive bolt pistol 27:08 Horse flinches, pulls ears back as though in pain 27:13 Tenth stunning attempt, horse continues to move and breathe 27:16 Horse is still moving 27:26 Eleventh stunning attempt at base of the brain; ears flick then the horse lurches forward and then violently falls backwards, but is still showing signs of movement 28:52 Side of stun box is opened and horse finally slides through

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Horse 35 – 15-year-old Belgian gelding, 18.1HH EID photo shows head markings as a blaze not stripe as entered, EID

Primary Location not filled in, EID owner is using phone number of agent.

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32:48 Large Belgian gelding slowly enters still-bloody stun box (two auction stickers, one white auction sticker: 107)

32:59 He repeatedly looks into suspending/butchering area and flinches away from it 33:36 Horse is shot too far back, between his ears and falls down (audio lag)

Can see the hole from the bullet in the horse’s poll

33:41 He falls backwards with head caught up on head stanchion chin lift 33:51 Side of stun box is lifted; horse is observed to have visible, excessive lip motion while sliding under door indicating that this horse may not have been fully unconscious 33:56 As with almost all previous horses, shooter follows horse into suspending/butchering area

39

VIDEO 11093915

Horse 37 – 12-year-old Belgian gelding, 19HH EID shows owner and signed name do not match, EID does not note markings on legs, EID Primary Location not filled in, EID owner is using phone number of agent.

40

00:15 Large Belgian gelding is urged into the stun box as we hear the drover yell "Hup!" (white auction sticker: 289; green kill-only sticker: 3737) 00:17 He sniffs the blood left from the horse before in head stanchion chin lift 00:25 Horse looks into suspending/butchering area 00:33 Horse trembling on his feet

00:49 Horse is shot with captive bolt pistol while shooter talking with someone, horse begins violently thrashing. Thrashing continues and is so strong, camera skips. 00:52 Horse is shot a second time with smaller gun 00:57 Male voice can be heard yelling "YEE-HAW!" 01:03 Horse's thrashing finally stops 01:13 Horse has been slowly sliding down in the box. Can see ears are still slightly moving and forward 01:24 Side of stun box lifted horse slowly slides down and out of box 01:25 Shooter watches as horse slides out of box then goes to the door of bleed room and looks down towards where the horse is then goes into bleed out room 01:46 The drover also goes into the bleed out room looking down toward where the shooter and horse appear to be located 01:53 Can hear someone say “ah, tabernac” as though something has gone wrong

02:10 Drover closes door to bleed out room

02:45 Drover opens door to bleed out room

03:00 Drover appears at front of box and hoses down his boots

03:15 Drover hoses chin lift and front of box

03:39 Drover closes door to bleed out and hoses out rest of box but misses the blood on the inside of the box where the horses can see and smell

41

Horse 38 – 11-year-old Belgian mare, 18.1HH EID Owner’s address is illegible (on original), EID does not note

markings on legs, EID Primary Location not filled in, EID owner using phone number of agent.

42

04:10 Large Belgian mare comes into the stun box while drover yells "Hup! Hup!" (4 white stickers, 2 oval stickers - white or USDA green?: 000 and 3741; white square sticker: 523) 04:24 Shooter says to horse: "Hey, whoa, whoa" 04:30 Horse is head shy, repeatedly turning her head away from the captive bolt pistol

04:43 She is shot with captive bolt pistol and falls (audio lag) 04:48 She’s shot a second time on the top of the head to the right 04:58 She’s shot a third time on the top of the head to the left; horse bounces up with impact 05:17 Side of stun box is lifted

08:48 Shooter hoses down stun box

43

Horse 39 – 12-year-old Belgian gelding, 19HH EID Primary Location not filled in, EID owner is using phone number

of agent.

44

33:21 Large Belgian gelding with a short mane haltingly enters the stun box to the screaming of the drover "HEY! HUP!"; horse backs out again. Can hear the drover yelling "HEY! HEY! HEY!", then "GIT! GIT!" 33:39 Sound of pawing heard 33:52 Can hear worker saying “Get in there” 33:56 Can hear what sounds to be whipping 34:15 Worker with coffee mug moves to around front of stun box attempting to draw horse to him with hand outstretched 34:30 Worker digs in garbage bin, grabs a rag and attempts to entice horse with it but only succeeds in worrying the horse more 34:40 Horse is continually being urged from behind, inches way into stun box, is unsteady on his feet 34:49 Can now see white auction sticker number 119 and green kill-only USDA sticker: 3751

34:50 Horse is shot with captive bolt pistol, jumps and falls to left side (audio lag) 34:56 Horse is shot a second time, aggressively and on poll, horse slides down into stun box 35:05 Horse can be heard thrashing on the floor of the stun box; workers can be heard yelling, shooter pretends to throw himself into the stun box and smiles, meanwhile, the workers can be heard yelling over the thrashing of the horse 35:12 Horse is apparently still thrashing as he lies on the floor of the box 35:18 Finally he’s quiet 35:19 Side of stun box is lifted by shooter 35:23 Shooter goes into suspending/butchering area

45

VIDEO 11101547

Horse 41 – 3-year-old Clydesdale gelding, 17HH EID Primary Location not filled in, EID owner using phone number of

agent.

02:50 A 3-year-old Clydesdale enters stun box (green kill-only USDA sticker: 3753) 2:51 Horse puts head down to sniff bloody stun box 3:02 Horse's knees buckle and he stumbles in stun box 3:04 Horse looks into suspending/butchering area 3:15 Horse is head shy and continually turns head to avoid captive bolt pistol

3:31 Horse is shot with captive bolt pistol; extremely poorly placed, grazes off horse's right ear 3:38 Shooter says: "Sorry, good girl." He is still standing 3:42 Horse turns head and looks back to move head as far away from shooter as possible, can see red line where bolt skinned across 3:48 Shooter takes second shot, incorrectly aimed too far to the right 3:55 Shooter takes a third shot on the horse's poll as the horse is down in the head stanchion 4:09 Side of stun box is lifted, horse slides through; a large amount of blood is left behind in the chin rest

46

Horse 43 – 13-year-old Belgian gelding, 18.3HH EID does not note markings on legs, EID photo shows a blaze not a

stripe.

47

07:21 Another large Belgian comes part way into box then backs out 07:28 Drover can be heard yelling "HEY! GO! GIT! HEY! H'YA!" as horse comes back into box 07:31 Drover yells "JESUS CHRIST!" 07:37 Belgian gelding comes into the still bloody stun box with continued yelling

by drover (white auction sticker: 134, green kill-only USDA sticker: 3748); he tries to back out again

07:47 He’s trembling, knees are buckling, having difficulty remaining standing

07:54 Horse is shot with captive bolt pistol; incorrectly placed too high and to the right, horse flails, legs moving rapidly 08:01 Horse is shot a second time; incorrectly placed at the horse's poll 08:09 Horse is shot a third time again incorrectly placed at the horse's poll, almost at base of horse's brain 08:20 Horse convulses and shakes his head, shooter looks to be ready to give a

fourth shot 08:32 Shooter moves past front of horse who appears to flinch at some noise 08:35 Side of stun box raised, horse partially slides down into stun box 08:40 Shooter grabs the horse's muzzle and grunts while pushing the horse's head down into the stun box 08:42 Horse’s ears can be seen flicking while he’s down in the box 08:52 Can see shooter pulling horse through with a crashing noise

Horse 46 – 14-year-old draft gelding, 18HH EID Primary Location not filled in, EID owner using phone number of

agent, owner’s signature and agent’s signature look very similar (on original photo).

48

23:56 Bay draft is urged into still-bloody stun box (3 white tags, round green kill- only USDA sticker: 3749 and white auction sticker: 115) 24:13 Horse is shot with captive bolt pistol and falls 24:18 Horse is shot a second time with captive bolt pistol; inaccurately placed on poll 24:27 Horse is shot a third time with captive bolt pistol while his ears were turning back; horse's body jumps with the shot again on top of head at the poll 24:33 Horse is shot a fourth time; this shot is violent and forceful; horse's body jumps higher with the shot, horse not going limp 24:50 Side of stun box is lifted, horse slides through leaving a great deal of blood behind

49

Horse 57 – 15-year-old buckskin gelding, 16HH EID owner using phone number of agent

50

28:32 Shooter tries luring in next horse 28:39 Horse does not want to enter; shooter tries to entice horse (buckskin Quarter Horse) into entering the stun box by holding out a rag from the garbage 29:11 Shooter throws towels back into garbage and uses baby talk to try to encourage horse into the chute 29:30 Shooter gets help from the drover 29:41 Can hear sounds of shod hooves 30:00 Buckskin horse, likely a Quarter Horse, enters then quickly backs up again (green kill-only USDA sticker: 3800) 30:10 Drover yells loudly "HEY! HUP! HA!" 30:17 Horse raises head and looks out open top left side of stun box 30:30 Horse is trembling, feet spinning on stun box floor

30:50 Horse is shot with the captive bolt pistol 30:55 Horse is shot a second time, can see left eye blink as shooter comes fast with captive bolt gun, body jumps 30:57 Second shot has reverse effect, horse on feet, moving and convulsing after shot 31:00 Horse is convulsing violently in box, blood pouring out of his head 31:15 He finally sinks to the floor but does not appear to be unconscious as his ears are still pricked up and his throat is moving 31:15 Side of stun box is lifted regardless

VIDEO 11112847

Horse 60 – 3-year-old possible Standardbred, 14.2HH EID lists two different heights – 15 and 14.2HH

Accompanying photo lists height as 14.2HH

51

12:09 Small bay mare, possibly a Standardbred, enters stun box slowly (EID shows auction tag 834, green kill only USDA sticker: 3812) 12:20 She sniffs around and is visibly shaking 12:26 She is frightened and nervously looking around, loud clanging noises can be heard 12:40 She looks into suspending/butchering area 12:42 She’s head shy, continually turning head away from captive bolt pistol 12:47 She’s shot with captive bolt pistol, can see whites of the her eyes as she looks back. She’s shot while looking to left

13:04 Her eyes appear to be moving after the first shot as her body slides down the stun box 13:04 She is shot a second time. A great deal of blood is seen on her forehead. Captive bolt pistol appears to get stuck in her head and has to be forcefully pulled out. She is trembling as she slides down into the box 13:22 A profuse amount of blood is left behind in the chin lift of the stanchion 13:35 She’s pulled into bleed out room 14:10 Sound of saws starting up again is heard. She was only shot around a half minute or so before the saws started up again.

52

Horse 63 – Bay Horse

34:35 Bay with straw in his/her mane very slowly enters stun box 34:57 Horse is nervously looking around, twitching 35:09 Horse is flinching, noticeably flinches when someone coughs

35:09 Horse is shot with captive bolt and starts kicking and convulsing 35:16 Horse is shot a second time, falls down into stun box

35:30 A person wearing a white hard-hat enters to look into the stun box 35:35 The shooter lifts the face of the horse to look into it 35:42 The shooter slaps face of horse while opening the door (First time this behaviour is observed from the shooter)

36:03 Horse pulled through 36:05 Individual in white hat leaves

53

VIDEO 11124148

Horse 64 – 12-year-old Standardbred, mare, 16.2HH She is seen in the video “Pasture to Plate” at 02:09 in the video.Her registered name was “Major Baby”. Her tattoo indicates that she

was 12 years old but her EID shows in the age box one number written over with another, EID owner using phone number of agent.

00:10 Thin black mare with black mane comes into still-bloody stun box (green kill- only USDA sticker: 3803) 00:15 She smells the bloody chin lift smearing the blood

00:24 She looks into suspending/butchering area 00:28 She’s shot with captive bolt pistol and falls but still has trembling

movement

54

00:35 Possible CFIA inspector returns (white hard hat, blue smock), looks in on horse

00:30 Shooter puts hand on top of her head 00:42 She suddenly rears back up as though attempting to rise to feet or flinching from shooter’s hand just as inspector is out of view then crashes down and falls to the right 00:44 Shooter says to the male possible CFIA inspector: "Probably dead" 00:50 Inspector responds "Maybe not...(inaudible)", then shooter smiles and winks. Then shooter raises side door of stun box seemingly oblivious to the fact that Major Baby is still moving 00:58 Shooter goes into suspending/butchering area

01:06-01:19 Possible CFIA inspector looks in at horse pulled into suspending/ butchering area

Horse 69 – Aged, bay gelding, 16.2HH EID shows two ages – 18 has been crossed out and 25 written in, EID

photo shows a stripe not a blaze as indicated.

55

12:03 Large, aged, bay with stripe comes quickly in to stun box (green kill-only USDA sticker: 3817) 12:15 Horse stares into suspending/butchering area for 20 seconds, until 12:35

12:35 Horse is shot while looking into bleed out room but angle is incorrect and placed too far to the right, horse sways, ears are still forward 12:40 Horse is shot a second time; again shot too high and on the right 12:41 Horse is starting to move, trying to right himself, then slides down 12:59 Shooter grabs and shakes muzzle of horse 13:03 Side of stun box is lifted, horse’s head snaps back as he slides under 13:19 Horse is pulled through stun box door

56

Horse 71 – 2-year-old Paint gelding, 15HH

57

16:45 Young Paint horse with white stripe in mane

17:15 He stares into suspending/butchering area 17:20 He is shot with captive bolt pistol; can hear squeaking of his

sweaty coat against the metal sides of the stun box as he slides down. Ears are still erect, though 17:26 He’s shot a second time, hear more squeaking

17:28 Can see what appears to be a cold branded capital letter S on right side of his neck 17:40 Shooter partially opens door to bleed out room 17:45 Horse falls down, white face spattered with blood; shooter sprays chin rest while horse’s head is still in view spraying the horse’s face

18:00 Horse appears to have voluntary movement of his head 18:10 Horse is pulled through into suspending/butchering area

58

VIDEO 11143118

Horse 96This horse is seen in the video “Pasture to Plate”.

22:51 Chestnut horse with flaxen mane (green kill-only USDA sticker: 9437) 23:00 Horse is head shy, repeatedly turns face away from captive bolt pistol 23:18 Horse appears to be having difficulty remaining standing, trips and slips 23:20 Both head and feet of horse are moving frantically 23:23 Horse pushes his/her head through the curtain to stare into the suspending/butchering area; frantically darts eyes around 23:33 Continues staring into the suspending/butchering area 23:34 There's a discussion about the horse with some laughter. The shooter seems to have put down the captive bolt pistol 23:36 Horse again pushes nose through curtain to stare into the suspending/butchering area 23:37 Shooter goes into suspending/butchering area 23:45 Horse attempts to jump out of stun box 23:49 Horse starts to become frantic, attempts to rear, looks again into suspending/butchering area

23:55 The drover comes in 23:56 Drover shoots the horse while horse is looking into suspending/butchering area; appears to be an incorrect angle 24:03 Drover shoots the horse a second time, does so extremely aggressively with lips pursed 24:13 Drover waves "Bye-Bye!" into horse's face and lifts side of stun box 24:24 Drover pulls lever that slams against the horse's head

24:31 Potential CFIA inspector leans over and looks in at the horse falling down into the stun box 24:34 Can see face of potential CFIA inspector 24:45 Horse is pulled through

59

Colour Key Red Inaccurate hit, horse remains conscious Purple Horse shows signs of fear Green Horse slips and falls Blue Horse vocalizing from fear

Brown Horse Shows signs of injury, infection or illness Orange CFIA present

THURSDAY, JULY 14, 2011VIDEO 11074922

Horse 8 This horse is seen in the video “Pasture to Plate”.

25:45 Tall chestnut horse with a flaxen, partially shaved mane enters still-bloody stun box, looking back with whites of eyes showing

25:57 Whinnying (sounds like horse next in line) 26:01 Horse sniffs stun box, looking around, keeping head low

26:03 Whinnying 26:05 Whinnying 26:07 Whinnying

26:09 Horse falls repeatedly until 26:36 (shot appears edited but is not, camera skipped because of movement in stun box. Look at shooter for perspective) 26:41 Horse is head shy, repeatedly turning face away from captive bolt pistol 26:46 Horse is shot with captive bolt pistol (audio lag) 27:04 Side of stun box is raised, horse falls through 30:35 Side of stun box is raised, horse falls through, flaccid

60

VIDEO 11090227

Horse 29 03:43 Chestnut slowly enters stun box; appears to have something wrong with left eye (enlarged eye with discharge)

03:51 Horse is urged into the stun box the rest of the way; is jittery 03:59 Horse is shot with captive bolt pistol and falls, convulsing 04:15 Side of stun box is raised 04:17 Shooter hoses down the stun box while the horse is still in it on floor

Horse 29 with enlarged, possibly infected left eye

61

VIDEO 11101527

Horse 54This horse is seen in the video “Pasture to Plate”.

14:44 Nervous bay horse enters stun box, twitchy, eyes darting 15:06 Horse is head shy and repeatedly turns face to avoid captive bolt pistol 15:16 Horse is shot with captive bolt pistol and lunges forward

15:17 Just-shot, the horse whinnies and convulses 15:24 Shooter attempts to shoot horse a second time but bolt does not discharge 15:26 Horse is shot a second time; inaccurately placed on poll

15:27 Horse whinnies again 15:35 Shooter talks to horse in baby-talk, difficult to hear 15:41 Horse slumps down into the stun box

15:43 Side of stun box raised, horse falls through

62

Horse 57This horse is seen in the video “Pasture to Plate”

21:16 Terrified chestnut horse is being urged into the stun box; can hear drover: "HEY! UP! Come on!” 21:21 Horse is thrashing in stun box so violently the film appears to skip 21:34 Horse is frantic, resisting moving forward but continually being pushed; twitching 21:35 Horse is shot with captive bolt pistol and falls (audio lag)

21:47 Side of stun box is raised 22:04 Horse is pulled through

27:29 Side of stun box is raised, horse falls through

Horse 6028:30 Large black and white Paint enters stun box, chin lift has pooled blood from previous horse 28:45 Horse is shot with captive bolt pistol while horse looking into suspending/ butchering area when shot

63

Horse 60 hit with the first shot.

28:50 Shooter tries to shoot the horse a second time into left temple but the bolt does not appear to discharge, horse appears to flinch from the touch of it

Horse 60 shot a second time under left ear.

28:55 Horse is hit a third time in same inappropriate location - under left ear - bolt discharges this time horse again appears to flinch at touch

64

Horse 60 shot a third time.

29:00 Horse’s body appears to be very rigid and starts to sink to floor 29:03 Wall of stun box is raised 29:26 Horse is pulled through

30:27 Whistling is heard 31:06 Shooter emerges from suspending/butchering area with a larger size captive bolt pistol which is covered in blood. He hoses the blood off of it. 31:15 Shooter returns just-hosed-off captive bolt pistol to suspending/butchering area 31:28 Shooter carries another captive bolt pistol back from the suspending/butchering area and places it on a shelf near the stun box

65

APPENDIX A

http://laws-lois.justice.gc.ca/eng/regulations/sor-90-288/FullText.html

66

APPENDIX A (cont’d)

http://laws-lois.justice.gc.ca/eng/regulations/sor-90-288/FullText.html

67

APPENDIX B

CFIA Manual of Procedures, Chapter 17, Annex E

http://www.inspection.gc.ca/english/fssa/meavia/man/ch17/annexee.shtml

“It is mandatory for all operators of Canadian Food Inspection Agency (CFIA) inspected facilities in Canada engaged in equine slaughter for edible purposes to have complete identity and medical records for all animals (domestic and imported) presented for slaughter. These records are referred to as equine information documents.”

Table of Contents include:

E.1 Introduction

E.2 Equine Information Document Elements

E.3 Equine Description Terms

E.4 Equine Lot Program

E.5 List of Veterinary Drugs Not Permitted For Use in Equine Slaughtered For

Food With Canadian Brand Name Examples

E.6 List of "Essential" Veterinary Drugs Permitted in Equine With a 6 Month

Withdrawal Period With Canadian Brand Name Examples

E.7 List of Veterinary Drugs Safe for Use in Equine Intended for Food Production

for Which Withdrawal Periods Have Been Determined with Canadian Brand Name

Examples

E.8 Frequently Asked Questions and Answers

68

APPENDIX B (Cont’d) Equine Information Document (EID) Template

A PDF interactive user-friendly individual animal EID developed for use by equine owners may be found at the Canadian Food Inspection Agency website:

http://www.inspection.gc.ca/english/for/pdf/c5624e.pdf

69

70

APPENDIX C

Canadian Food Inspection Agency

List of Federally Registered Meat Establishments and their Licensed Operators

Last Update : 2011/11/29

http://active.inspection.gc.ca/scripts/meavia/reglist/reglist.asp?lang=e

Telephone numbers:Ending with /F = Fax Number.Ending with /I = Inspection Number. Not ending with anything = Location Number. * at the end of the operator's name means the establishment is temporarily inactive. The licensed operator of a registered establishment has a HACCP system (prerequisite programs and HACCP plans) in place that meets FSEP requirements as required by section 29 of the MeatInspection Regulations, 1990

Registration Number

Name of the OperatorAddress(s)

FunctionCodes

TelephoneNumber(s)

076

VIANDE RICHELIEU INC./RICHELIEU MEAT INC.--------------- Location Address: :595 RUE ROYALE, MASSUEVILLE, QC, J0G 1K0Mailing Address: :C.P. 101, MASSUEVILLE, QC, J0G 1K0

1abehi, 3x,6x,11ADGHLNR,

(450) 788-2667(450) 788-2622/F(450) 788-2061/I

505

LES VIANDES DE LA PETITE-NATION INC.Also Doing Business As Name :LES CERFS DE BOILEAU --------------- Location Address: :517, RANG STE-JULIE EST, ST-ANDRÉ-AVELLIN, QC, J0V 1W0 Mailing Address: :421, RUE ST-PAUL ESTBUREAU 200, MONTRÉAL, QC, H2Y 1H5

1abcdeh, 3xfg,6xfg,11ADGHKN,

(819) 983-7941(819) 983-4041/F(819) 983-7941/I

506

BOUVRY EXPORT CALGARY LTD.--------------- Location Address: :S.W. 1/4 SEC. 17TWP. 9, RG. 25, W. 4, HWY # 3 EAST, FORT MACLEOD, AB,Mailing Address: :P.O. BOX 2024, FORT MACLEOD, AB, T0L 0Z0

1acehij, 3x,11ADGHN,

(403) 553-4431(403) 553-3037/I(403) 553-3222/F

657

CANADIAN PREMIUM MEATS INC.--------------- Location Address: :3401 - 53RD AVE., LACOMBE, AB, T4L 2L6 Mailing Address: :RR 4, RED DEER, AB, T4N 5E4

1aehi, 3x,11ADHLMNV,

(403) 782-9366(403) 782-7163/F(403) 782-7991/I

This search found 4 establishment(s).

71

APPENDIX C (Cont’d)

http://active.inspection.gc.ca/scripts/meavia/reglist/reglist.asp?lang=e

Key To Function Codes:1. Slaughter a) Cattle b) Calves c) Sheep, lambs and goats d) Swine e) Horses f) Poultry g) Rabbits h) Others 1. Ritual Slaughter i) Halal j) Kosher 2. Canning f) Poultry Meat x) Red Meat g) Rabbit Meat 3. Boning and Cutting f) Poultry Meat x) Red Meat g) Rabbit Meat 4. Edible Rendering5. Casing Preparation6. Other Processing f) Poultry Meat x) Red Meat g) Rabbit Meat 7. Packaging, Labelling and Storing8. Inedible Rendering9. Facilities for inspection of detained or imported meat products A) Cooked, frozen, boneless beef from South America. B) Other than cooked, frozen, boneless beef from South America. C) Not requiring refrigeration. US) From the United States of America. 10. Storage Only A) Cold Storage B) Dry Storage 11. Establishments approved for export to specified markets. Please be advised that the approval of the establishments may be limited to specific products and/or that restrictions may apply. For details on the eligibility status of the establishment click on the following link and consult the applicable section on the market of destination of chapter 11:http://www.inspection.gc.ca/english/fssa/meavia/man/ch11/11.7e.shtml

A) Mexico C) Japan D) United States F) Australia G) South Africa H) European Union* & Switzerland I) Ukraine J) Argentina K) Brazil L) Hong-Kong N) Chile O) Malaysia P) Indonesia R) Russia S) China B) Saudi Arabia M) Singapore Q) Peru V) Vietnam *With the exception of St-Pierre et Miquelon 12. Trichina Treatment Facilities

APPENDIX D

Equine Anatomy

72

APPENDIX E

Photographs of Horses in Overnight Holding Pens

Horses in overcrowded holding pens - no food or water present

Thin horses, with “downer” horse on floor on left at risk of being trampled

73

“Downer” horse at risk of being trampled; metal shoe still on right fore hoof

Close up of “downer” horse

74

Thin and frightened horses in holding pen at La Petite-Nation

75

Fit but thin Thoroughbred in holding pen

Kill-only USDA stickers listed acronym USEZ

76

APPENDIX F

Sampling of Photos Attached to EID Forms

Showing tattoo

77

EID Forms

This registered Standardbred’s name was “Hurricane Jeff”. He was 8 years old but his EID states 5. In his racing career he earned $108,446 for his owners and his ancestry is traced back to Cam Fella.

78

Below is an EID purportedly for an 18-year-old mare that was listed as a workhorse.

This EID has multiple errors. The EID owner and signature do not match. The mare’s age was scratched out, and written over beside it is the number “18” (on closer examination of the original photo, the scratched out number appears to be “30”). Instead of a phone number for the owner, the agent’s number is written in that field. Under Drugs section, white-out tape has been used to cover over the ‘YES’ box with a large box and an ‘X’ marked in the ‘NO’ box.

It seems highly doubtful that this fancy, show-type horse is an 18 or 30-year-old workhorse.

79

The EID below shows what could possibly be a 20-year-old pregnant mare who appears to be close to term. Her enlarged belly and prominent milk vein leads us to believe that she was 2 weeks to a month before foaling, however, the EID does not state the sex of this horse.

80

On this EID someone has written the word ‘MULE’ on the description. As well, 3 different heights have been entered: 12.2 and 15.2 on the EID, and 15.1 on the accompanying photo.

The photo attached to this EID is that of a horse, not a mule.

81

APPENDIX G

Stun Box Design

82

83

APPENDIX H

Discarded halters near the stun box.

84

Horse carcasses inside the cold storage room.

85

Horse hides.

86

Skids piled high with horse hides.

87

Canadian Horse Defence Coalition 150 First Street P.O. Box 21079

Orangeville, Ontario L9W 4S7 Phone: (250) 768-4803

Email: [email protected]: www.defendhorsescanada.org

88

EXHIBIT 17

EXHIBIT 18

���� I� � ��������� T���� �������� T���� �1� �������

Credit: Vickery Eckhoff/N Date: January 08, 2012

In pictures: Life next door to the Dallas Crown horse slaughter plant in Kaufman, Texas

As Mayor from 2003-2007, Paula Bacon helped shut Dallas Crown, ending decades of extreme environmental violations by the horse slaughterhouse, which is owned by the Belgian meat packer, Chevideco.

“They said they were good corporate citizens,” Bacon states in a recent interview. "I believe it's more accurate to describe them as corporate thugs."

Dallas Crown Horse Slaughter Plant—Kaufman, Texas (2005)

Official and city staff documents describe Dallas Crown’s pervasive environmental violations, including "blood flowing east and west in the ditches from your plant," "It has been over 59 days and no apparent cleanup has occurred," "Your system has not improved and subsequently it has gotten a lot worse," "Words cannot express the seriousness" of recent violations and the "adverse effects on the waste water treatment plant," and "Please be sure trailers are secured before leaving your premises to prevent spills," noting also "bones and blood laying in front of the facility," problems with bones and parts in neighboring yards and the attraction of "dogs and other animals.”

Handling Dallas Crown's sewage was about to cost Kaufman $6 million for a new waste water treatment plant. Within two weeks of the plant's closure, waste water plant capacity increased dramatically.

Dead Horse On �orklift �t Dallas Crown Slaughter Plant—Kaufman, Texas (2005)

In �9�6, Dallas Crown’s plant manager promised to slaughter only out�of�state horses that had outlived their usefulness. These would be killed �in a fraction of a second,” with a captive�bolt device, he claimed. Other promises included having a ��SD� inspector on site each day to ensure that the plant operates under government regulations and the plant will work under the guidance of the humane society.”

Dallas Crown Holding Pens—Kaufman, Texas (2006)

�lthough Dallas Crown violated humane laws by accepting blind, lame, severely in�ured and untreated, sick horses from kill buyers, most of the horses slaughtered were healthy and fat, as residents of Kaufman observed by regularly watching the pens.

�There were all these shiny, groomed horses. Who shoes a horse and sends it to slaughter�” asks �acon. �Someone had cared for and about these horses only a few days earlier."

�The stench was terrible,” says �ualine �ldridge, a nurse at Texas Health �esources Presbyterian Kaufman. She and her husband, �obert �ldridge, a respiratory therapist, own property abutting the plant, in a low�income black neighborhood. �The noise from clanging and whinnying when they unloaded the horses at midnight was �ust awful,” he says.

Dallas Crown Horses—Kaufman, Texas (2005)

�There were great horse properties for sale in Kaufman back when the plant was operating, with sandy soil and big, mature trees and really great prices—�ust what my clients from the Dallas��ort Worth area with horses were asking for,” says Paula Hooper Denmon, of Town and Country �irls �eal �state. ��ut they wouldn’t buy in Kaufman. They were afraid they’d come home from work and find their barns empty. They didn’t even want to drive into town. It was tainted.”

W���I��� ���T TWO I����S (� 6��) ��� ��T�����Y ���PHIC

Dallas Crown Humane �iolations—Kaufman, Texas (2005)

�rom �an. � � �ov. ��, 2005, �SD� inspectors at Dallas Crown photographed violations committed under the Commercial Transport of �quines Slaughter �ct, but didn’t act on them, according to a 906�page �SD� document for that period obtained under the �reedom of Information �ct.

The document showed extensive, in�uries, some intentionally inflicted by kill buyers and transporters, like eyes gouged out to keep horses from fighting on the trailers, especially since stallions were packed in next to geldings and mares. �oth mares and geldings were also sub�ected to intentional blinding.

Dallas Crown Humane �iolations—Kaufman, Texas (2005)

Horses suffering from severed legs, compound fractures, head and other serious in�uries, still births and death by trampling in double�decker trailers were some of the many photographs captured in the 906�page �SD� document.

�o licenses were revoked and no penalties were assessed until 200�, when one buyer, �eroy �aker of Ohio, was ordered to pay $�62,�00—but refused, calling the charges �bogus.” In �ay, 20��, following public pressure, the �S District Court for the �orthern District of Ohio ordered garnishment of �aker’s bank accounts to collect the outstanding monies.

Dallas Crown Offal Container—Kaufman, Texas (2006)

Open containers of bloody hides, horse heads, legs and offal were left outside and also transported, leaking blood, through the community. �Seeing horses’ carcasses on the conveyor belt would break anyone’s heart,” says �ualine �ldridge.

600��allon �lood Spill Outside Dallas Crown Plant—Kaufman, Texas (200�)

�Sometimes, when they killed, they didn’t move the container for a week. That’s how long it took to fill it with guts,” says �obert �ldridge. �The longer it sat, the more it stunk, the more flies and vermin it attracted.”

�ulie Caramante, an independent equine cruelty investigator from Houston, describes following a Dallas Crown rig and seeing body parts fall on the highway. �The cops pulled it over. I watched as the driver was forced to climb down into the container to secure the load,” says Caramante.

�ualine �ldridge, �obert �ldridge and �ayor Paula �acon (2005)

Kaufman�born �obert �ldridge and his wife, �ualine �ldridge, have lived in the ”�oggy �ottom” neighborhood bordering the plant since �9�5. In September, 2005, �ualine and �obert traveled with �ayor �acon to Capitol Hill to speak out on the plant’s effect on their neighborhood, property and town.

�One by one, our neighbors couldn’t take it and left the neighborhood. It was horrible,” �obert �ldridge says. �It stunk like manure and decaying flesh. �verybody was affected. The kids didn’t want to go out and play.”

�ualine said, �It was all about money for Dallas Crown. They wanted the plant, but not in their own backyards. �ust like �eltex, which was in a low�income Hispanic neighborhood in �ort Worth. They didn’t care about us.”

�ulture in Tree—Kaufman, Texas (2005)

�ultures, snakes, rats, cockroaches and flies plagued neighbors while Dallas Crown was operating. �We get an occasional vulture now,” �obert �ldridge.

Dallas Crown Horse Slaughter Plant—Kaufman, Texas (200�)

The Website of Dallas Crown’s �elgian owner, Chevideco, features the Kaufman plant alongside five other worldwide slaughterhouses operating today in �elgium, �omania, �rance, �rgentina and �exico.

�Chevideco �v has clear engagements concerning a dignified treatment of live animals, both during transport and during their stay in the slaughterhouse. �t the moment of purchase, Chevideco �v pays utmost heed to a qualitative selection of the animals. �oth during and after the slaughtering, the veterinary services guarantee the inspection of the meat intended for human consumption. �ll operations within Chevideco are sub�ect to the most stringent H�CCP quality standards and I�S 2009�20�0 standards. The entire process takes place under the most rigorous hygienic and animal�friendly conditions.”

�rom �respect for animals,” one of four main sub�pages featured on Chevideco’s Web site homepage

�ew product development includes �a new branch of the meat industry, vi�. the transformation of meat offal into pet food,” says Chevideco’s web site.

Town Square With �ew Shops and Cafes—Kaufman, Texas (20�2)

Kaufman is being revitali�ed since Dallas Crown’s closing. Property crimes fell by half, real estate prices have gone up and the town has been in a development and expansion phase. There’s a new �aptist church youth community center built near the Dallas Crown facility and an �0�unit affordable senior�citi�en apartment complex spearheaded by the Kaufman �eighborhood Development Organi�ation, Inc., a non�profit organi�ation.

�We go outside, now. We can barbecue and the kids can play. There’s a much better smell,” says �obert �ldridge. �If they ever try and come back,” he added, �we’ll fight them. We’re not giving up our neighborhood. We won’t let them come back.”

EXHIBIT 19

http���www.animallawcoalition.com�horse�slaughter�article�6�6

Open Letter to State Legislatures Considering Pro-Horse Slaughter Resolutions

Posted Feb 13, 2009 by lauraallen

o Horse Slaughter

Former Mayor Paula Bacon City of Kaufman

Kaufman, TX 75142

Dear State Legislator:

You will soon be asked to vote on ... legislation regarding the commercial slaughter of American horses of which you probably have very little firsthand knowledge. No doubt you have heard from lobbyists and organizations who want you to support the practice, but before you do, you should ask yourself why the residents of Texas and Illinois worked so hard to rid their states of their horse slaughter plants. The answer may surprise you.

As a mayor who lived with this plague in her town for many years, who knows what the horse slaughter industry really is and what it does to a community please allow me to tell you what we experienced. The industry caused significant and long term hardship to my community which was home to Dallas Crown, one of the last three horse slaughter plants in the United States.

All three plants were foreign-owned, and since the market for horsemeat is entirely foreign, the industry will always be dominated by these foreign interests. The corporations involved in this industry have consistently proven themselves to be the worst possible corporate citizens.

The Dallas Crown horse slaughtering facility had been in operation in Kaufman since the late 70's and from the beginning had caused problems both economically and environmentally. I have listed some of the specific issues below.

I will gladly provide you with detailed reports from my former City Manager, Police Chief, and Public Works Director regarding odor and wastewater effluence violations at the Dallas Crown horse slaughter plant in the City of Kaufman.. The reports reference "decaying meat [which] provides a foul odor and is an attraction for vermin and carrion," containers conveyed "uncovered and leaking liquids," there are "significant foul odors during the daily monitoring of the area," and "Dallas Crown continually neglects to perform within the standards required of them."

Therefore, in August of 2005, our City Council decided by unanimous decision to send the Dallas Crown issue to the Board of Adjustments for termination of their non-conforming use status. In March of 2006, the Board of Adjustments voted to order Dallas Crown closed, but the plant was able to tie the enforcement up in the courts until they were finally closed under state law in February of 2007.

Dallas Crown repeatedly described itself as a "good corporate citizen." I will be straightforward in asserting that they are the very antithesis of such.

o Dallas Crown had a very long history of violations to their industrial waste permit, 'loading' the capacity of the wastewater treatment plant.

o Dallas Crown denied the City access to their property for wastewater testing beginning October 1, 2004 until July 6, 2005 , despite requirement by city ordinance, city permit agreement, and court order.

o City staff reported that a $6 million upgrade to our wastewater treatment plant would be required even though the plant was planned and financed to last through 2015.

o Odor problems resulting from the outside storage of offal and hides over several days persisted not only in traditionally African-American neighborhood known as "Boggy Bottom", but at the nearby Presbyterian Hospital , the daycare center, and surrounding areas.

o Transport of offal and fresh hides on City and state thoroughfares is conducted in leaking containers without covers.

o City documents reveal an extended history of efforts to have Dallas Crown address various environmental issues. Reports include descriptive language including such as "blood flowing east and west in the ditches from your plant," "It has been over 45 days [it had been 59 days] and no apparent cleanup has occurred," "Your system has not improved and subsequently it has gotten a lot worse," "Words cannot express the seriousness" of recent violations and the "adverse effects on the wastewater treatment plant," and "Please be sure trailers are secured before leaving your premises to prevent spills," noting also "bones and blood laying in front of the facility," problems with bones and parts in neighboring yards and the attraction of "dogs and other animals."

o In response to 29 citations for wastewater violations, each accompanied by a potential fine of $2,000, Dallas Crown requested 29 separate jury trials, potentially causing yet another economic strain to the City's budget. We could, of course, not afford to litigate in order to extract the fines

o Dallas Crown took 11 months to submit a mandatory "sludge control plan" to assist efficient operation of the wastewater treatment plant though City staff requested it orally and in writing many times.

o The City Manager advised me that the City would have to spend $70,000 in legal fees because of Dallas Crown problems, which was the entire legal budget for the fiscal year.

o During this period, Dallas Crown paid property taxes that were less than half of what the City spent on legal fees directly related to Dallas Crown violations.

o Generally, Dallas Crown has the economic ability to prevail, to exceed the constraints of the City's budget.

Dallas Crown had a negative effect on the development of surrounding properties, and a horse slaughter plant is a stigma to the development of our city generally. I have since learned that these problems were mirrored at the other two plants. Fort Worth's Beltex horse slaughter plant also violated Ft. Worth's wastewater regulations several times, clogged sewer lines, and both spilled and pumped blood into a nearby creek (San Antonio Current, June 19, 2003 ). Texas State Rep. Lon Burnam, D-Fort Worth, whose district includes Beltex, and Rep. Toby Goodman, R-Arlington, fought hard against legislation that would have legalized horse slaughter in Texas in 2003.

The horse slaughter plant in DeKalb , IL had a similar pattern. It was destroyed by fire in 2002, and rebuilt in 2004. It was charged and fined by the DeKalb Sanitary District almost every month from the reopening until its closing in 2007 under a new state law for consistently exceeding wastewater discharge guidelines. I can provide you with the documentation of those violations. Like Dallas Crown, Cavel refused to pay their fines for years.

During this time, I learned that an estimated $5 million in Federal funding was being spent annually to support three foreign-owned horse slaughter plants! And when the Dallas Crown tax records were

exposed in the city's legal struggle, we found that they had paid only $5 in federal taxes on a gross income of over $12,000,000!

Moreover, the parent company of Cavel has since moved its operations to Canada and continued to slaughter American horses. In Canada they have apparently become even more blatant, dumping huge untreated piles of entrails onto open ground and even using a tanker truck to discharge blood and refuse into a local river.

I have mentioned only the pollution issue, but this is but one negative aspect of horse slaughter. I have subsequently learned of a USDA document containing 900 pages of graphic photos that show the horrors that the horses were subject to. Behind the privacy fences of these plants, trucks arrived continuously and on those trucks was every form of inhumane violation one can imagine from mares birthing foals to horses with eyes dangling from their sockets and legs ripped from their bodies.

The more I learn about horse slaughter, the more certain I am: There is no justification for horse slaughter in this country. My city was little more than a door mat for a foreign-owned business that drained our resources, thwarted economic development and stigmatized our community. Americans don't eat horses, and we don't raise them for human consumption. There is no justification for spending American tax dollars to support this industry at the expense of Americans and our horses.

Sincerely,

Former Mayor Paula Bacon Kaufman, TX 325-665-2043 cell

For more on pending pro-horse slaughter bills in state legislature, read this.