SLE 5000 HFOV Dr.ALLAM ABUHAMDA CONSULTANT NEONATOLOGIST
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Transcript of SLE 5000 HFOV Dr.ALLAM ABUHAMDA CONSULTANT NEONATOLOGIST
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CONSULTANT NEONATOLOGIST
DR ALLAM ABUHAMDA
SLE 5000HFOV
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Introduction
• Delivers a small tidal volume, usually less than or equal to anatomical dead space volume.
• While HFV’s are frequently described by their delivery method, they are usually classified by their exhalation mechanism (active or passive)
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Introduction
• Henderson first published his findings in 1915, assessing dead space relationship in ventilation.
• He stated, “there may easily be a gaseous exchange sufficient to support life even when Vt is considerably less than dead space
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High Frequency Ventilation
• Types of HFV’s Approved for use in both Neonates and Pediatrics• SLE5000
HFOV• SensorMedics 3100A HFOV• Bird Volumetric Diffusive HFPPV
• Types of HFV’s Approved for use in Neonates Only• Bunnell Life Pulse HFJV• Infrasonics Infant Star (discontinued)
HFFI
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SLE5000
• Electrically powered, electronically controlled
• Conventional and HFOV ventilator
• Paw of 3 - 35 mbar• Delta P from 4 – 180
mbar• Frequency of 3 - 20 Hz• I:E Ratio 1:1• Active exhalation
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Indications of HFOVNeonatal
RDS/HMDAir leak syndromesMASPPHNCDH
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Ventilator Induced Lung Injury
• Barotrauma• Volutrauma• Stretch Injury• Biochemical Injury
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Absence of SurfactantAtelactasisHigh Distending PressuresAirway Stretch / DistortionCellular Membrane DisruptionEdema Higher FIO2 , Volumes, Pressures PIE, BPD
Pulmonary Injury Sequence of the neonatal patient:
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Pulmonary Injury Sequence
If we cannot prevent the injury sequence , then the target goal is to interrupt the sequence of events.
High Frequency Oscillation does not reverse injury, but will interrupt the progression of injury.
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Ventilator Induced Lung Injury
Premature baboon model Coalson J. Univ Texas San Antonio
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Pulmonary Injury Sequence
• There are two injury zones during mechanical ventilation• Low Lung Volume
Ventilation tears adhesive surfaces
• High Lung Volume Ventilation over-distends, resulting in “Volutrauma”
• The difficulty is finding the “Sweet Spot”
Froese AB, Crit Care Med 1997; 25:906
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HFOV Principle:Pressure curves CMV / HFOV
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Ventilator Induced Lung Injury
• HFOV with Surfactant as Compared to CMV with Surfactant in the Premature Primate–HFOV resulted in
•Less Radiographic Injury•Less Oxygenation Injury•Less Alveolar Proteinaceous Debris
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HFOV
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Theory of Operation
• Oxygenation is primarily controlled by the Mean Airway Pressure (Paw) and the FiO2
• Ventilation is primarily determined by the stroke volume (Delta-P) and the frequency of the ventilator.
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HFOV effectively decouples:Oxygenation & Ventilation
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HFOV Principle:Pressure curves CMV / HFOV
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Optimized Lung Volume Strategy:
Increase Lung Volume above critical opening pressure to the Optimum and keep it there in
Inspiration and Expiration.
Benefits: - homogenous gas distribution- reduced regional atelectasis- maximized gas exchange area and pulmonary blood flow- better matching of ventilation/perfusion- reduction of intrapulmonary shunting - reduced Oxygen exposure
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Optimized Lung Volume Strategy:
Decrease Tidal Volumes to less or equal to dead space and increase frequency.
Benefits: - enhanced gas exchange due to combined gas transport mechanisms
- no excessive volume swings- reduced regional over-inflation
and stretching - reduced Volutrauma
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“Open up the lung up and keep it open!”
Burkhard Lachmann, 1992
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Primary control of CO2 is by the stroke volume produced by the Delta P Setting.
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Regulation of stroke volume• The stroke volume will increase if
– The amplitude increases (higher delta P)
Stroke volume
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Secondary control of PaCO2 is the stroke volume produced by the set Frequency.
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Regulation of stroke volume• The stroke volume will increase if
– The amplitude increases (higher delta P)
– The frequency decreases (longer cycle time)Stroke volume
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CDP=FRC=Oxygenation
HFOV Principle
+ + + + +
- - - - -
AmplitudeDelta P =Tv =Ventilation
I
E
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Pressure transmission
Gerstmann D.
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Airway Pressure Transmission HFOV :
TransmissionET Tube Trachea Alveolus
CDP / MAP= Lungvolume= Oxygenation
Pressure
AmlitudeDelta P =TV =Ventilation
I
E
+ + +
+ + + + + + +
_ _ _
_ _ __ _ _
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HFOV Mechanisms of Gas Transport
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Mechanisms of HFOV Gas Exchange
There are six mechanisms of gas exchange during HFOV Convective Ventilation Asymmetrical Velocity Profiles Taylor Dispersion Pendeluft Molecular Diffusion Cardiogenic Mixing
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Practical preparationAvoid leak around the E.T tubeTc PO2,CO2,Pulse oxymeter and invasive
blood pressure monitoringBaseline CXROptimize blood pressure and
perfusion(volume replacement and inotropes)
Muscle relaxant/sedationReusable low compliance circuits must
be used
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NURSING CARE
Perform through suction before connecting to the oscillator.
Assess patient upon commencement of HFOV.
Monitor vital signs, chest wiggle must be evaluated upon initiation and followed closely thereafter.
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Precautions
If chest wiggle diminishes it may be ET tube moved or obstructed.
Chest wiggle on one side indicates patient developed pneumothorax,thus chest wiggle assessment should be performed after repositioning
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Precautions
Auscultation the chest by putting in standby mode.
A closed suction should be used. It is not necessary to disconnect the
patient to suction as this will potentially derecruit lung volumes.
The point at which the ET tube is cut and secured at lips should be initially noted this measurement is reference
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Precautions
Evaluation of lung expansion on CXR
Check capillary refill, skin color and temperature
Comparing central and peripheral pulses
Monitoring of ECG TracingFrequent CXR’s blood gases in initial stabilization period
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Precautions
Optimal lung volume for oxygenation is 8-9 rib inflation
Blood pressure and perfusion should be optimized prior to HFOV,any volume replacement should be completed and inotropes commenced if necessary
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Precautions
Muscle relaxants are not indicated since spontaneous respiratory effort will be a clinical indicator of adequacy of ventilation
Sedation with opiates is often indicated
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THANKS