Peran Zat Gizi Mikro bagi Tubuh blok 5(1).pdf

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    Rifana Cholidah

    *

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    Nutrients needed in relatively

    small amounts to supportnormal health and body

    functions. Vitamins and

    minerals are micronutrients

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    *are carbon-containing compounds that regulatea wide range of body processes.

    *Of the thirteen vitamins recognized asessential, humans can synthesize only smallamounts of vitamins D and K, so we mustconsume virtually all of the vitamins in ourdiets.

    *Almost everyone who eats a varied andhealthful diet can readily meet their vitaminneeds from foods alone.

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    Vitamin A*

    Thiamin

    Riboflavin

    Niacin

    Vitamin B6

    Vitamin B12

    Folate

    Pantothenic acid

    Biotin

    Choline

    Vitamin C

    Vitamin D*

    Vitamin E*

    Vitamin K*

    * fat-soluble vitamin

    Calcium

    Chromium

    Copper

    Fluoride

    Iodine Iron

    Magnesium

    Manganese

    Molybdenum

    Phosphorus Potassium

    Selenium

    Sodium

    Zinc

    *Vitamin and Minerals

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    A, D, E, and K are fat soluble vitamins

    They are found in the fatty portions offoods (butterfat, cod liver oil, corn oil, and

    so on) and are absorbed along with dietary

    fat

    Fat-containing meats, dairy products, nuts,seeds, vegetable oils, and avocados are all

    sources of one or more fat-soluble

    vitamins.

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    *In general, the fat-soluble vitamins are readily

    stored in the body’s adipose tissue; thus, we

    don’t need to consume them every single day.

    *While this may simplify day-to-day menu

    planning, there is also a disadvantage to our

    ability to store these nutrients. When we

    consume more of them than we can use, theybuild up in the adipose tissue, liver, and other

    tissues and can reach toxic levels. Symptoms of

    at-soluble vitamin toxicity, described in Table

    below, include damage to our hair, skin, bones,

    eyes, and nervous system.

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    Vitamin Main function Reliable food

    source

    Toxicity/Deficiency

    A (retinol,

    retinal,retinoic acid)

    Required for

    ability of eyes

    to adjust to

    changes in

    light

    Protects color

    vision

    Assists cell

    differentiation Required for

    sperm

    production in

    men and

    fertilization in

    women

    Contributes tohealthy bone

    Contributes to

    healthy

    immune system

    Preformed retinol:

    Beef

    and chicken liver,

    egg

    yolks, milk

    Carotenoid

    precursors:

    Spinach, carrots,

    mango, apricots,cantaloupe,

    pumpkin,

    Yams

    Toxicity : Fatigue;bone and joint

    pain; spontaneous

    abortion and

    birth defects of

    fetuses in pregnant

    women; nausea and

    diarrhea;

    liver damage; nervoussystem damage;

    blurred vision;

    hair loss; skin

    disorders

    Deficiency : Nightblindness,

    xerophthalmia;impaired growth,

    immunity, and

    reproductive

    function

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    D (cholecalciferol) Regulates

    blood calcium

    levels

    Maintains bonehealth

    Assists cell

    differentiation

    Canned salmon and

    mackerel, milk,

    fortified

    cereals

    Toxicity:Hypercalcemia

    Deficiency: Rickets in

    children;osteomalacia and/or

    osteoporosis

    in adults

    E (tocopherol) • As a powerfulantioxidant,

    protects cellmembranes,

    polyunsaturate

    d fatty acids,

    and vitamin A

    from oxidation

    • Protects white

    blood cells

    • Enhances

    immune

    function

    • Improves

    absorption of

    vitamin A

    Sunflower seeds,

    almonds,

    vegetable

    oils, fortified

    cereals

    Toxicity: RareDeficiency:Hemolytic anemia;

    impairment of

    nerve, muscle,

    and immune

    function

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    K

    (phylloquinone,menaquinone,

    menadione)

    Serves as a

    coenzyme duringproduction of

    specific

    proteins that

    assist in blood

    coagulation and

    bone metabolism

    Kale, spinach,

    turnipgreens, brussels

    sprouts

    Toxicity: None

    knownDeficiency:Impaired blood

    clotting;

    possible effect

    on bone

    health

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    Vitamin C (ascorbic acid) and the B vitamins(thiamin, riboflavin, niacin, vitamin B6,

    vitamin B12, folate, pantothenic acid, andbiotin) are all water-soluble vitamins

    They are found in a wide variety of foods,including whole grains, fruits, vegetables,meats, and dairy products. They are easily

    absorbed through the intestinal tract directlyinto the bloodstream, where they then travelto target cells.

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    *With the exception of vitamin B12, we do

    not store large amounts of water-soluble

    vitamins. Instead, our kidneys filter fromour bloodstream any excess amounts, and

    they are excreted in urine.

    *Because we do not store large amounts of

    these vitamins in our tissues, toxicity israre.

    *When it does occur, however, it is often

    from overuse of high-potency vitamin

    supplements.

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    vitamin Functions Food sources Toxicity/

    Deficiency

    Thiamin

    (vitamin B1)

    Required as

    enzyme cofactorfor carbohydrate

    and

    amino acid

    metabolism

    fortified cereals,

    enriched rice andpasta, peas, tuna,

    legumes

    Toxicity: None

    knownDeficiency:Beriberi; fatigue,

    apathy, decreased

    memory,

    confusion,irritabili

    ty, muscle

    weakness

    Riboflavin

    (vitamin B2)

    Required as

    enzyme cofactor

    for carbohydrate

    and fat

    metabolism

    Beef liver, shrimp,

    milk

    and dairy foods,

    fortified

    cereals, enrichedbreads and grains

    Toxicity: Noneknown

    Deficiency:Ariboflavinosis;

    swollen mouth andthroat; seborrheic

    dermatitis;

    anemia

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    Niacin,

    nicotinamide,

    nicotinicacid

    Required for

    carbohydrate

    and fatmetabolism

    Plays role in

    DNA replication

    and repair and

    cell

    differentiation 

    Beef liver, most

    cuts of

    meat/fish/poultry,fortified

    cereals, enriched

    breads and grains,

    canned tomato

    products

    Toxicity: Flushing,liver damage,

    glucoseintolerance,

    blurred

    vision

    differentiation

    Deficiency:Pellagra; vomiting,

    constipation, ordiarrhea; apathy

    Pyridoxine,

    pyridoxal,

    pyridoxamine

    (vitamin B6)

    Required as

    enzyme cofactor

    for carbohydrate

    and amino acid

    metabolism  Assists

    synthesis of

    blood cells 

    Chickpeas

    (garbanzo

    beans), most cuts

    of

    meat/fish/poultry,fortified cereals,

    white potatoes

    Toxicity: Nervedamage, skin

    lesions

    Deficiency:

    Anemia; seborrheicdermatitis;

    depression,

    confusion, and

    convulsions

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    Folate (folic acid)  Enzyme cofactorfor amino acid

    metabolism

    Required for DNAsynthesis

    Involved in

    metabolism of

    homocysteine 

    Fortified cereals,

    enriched breads and

    grains, spinach,

    legumes (lentils,chickpeas,

    pinto beans),

    greens (spinach,

    romaine lettuce),

    liver

    Toxicity: Maskssymptoms of

    vitamin B12

    deficiency,specifically

    signs of nerve

    damage

    Deficiency:Macrocytic anemia;

    neural tube defects

    in a developingfetus; elevated

    homocysteine

    levels

    Cobalamin

    (vitamin B12)

    Assists with

    formation of

    blood

    Required for healthynervous

    system function

    Involved as enzymecofactor

    in metabolism of

    homocysteine

    Shellfish, all cuts of

    meat/fish/poultry,

    milk

    and dairy foods,fortified

    cereals

    Toxicity: Noneknown

    Deficiency:

    Pernicious anemia;tingling and

    numbness of

    extremities; nervedamage;

    memory loss,

    disorientation,

    and dementia

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    Pantothenic acid   Assists with fatmetabolism 

    Meat/fish/poultry,

    shiitake

    mushrooms,

    fortified

    cereals, egg yolk

    Toxicity: None

    known

    Deficiency: Rare

    Biotin Involved as enzymecofactor

    in carbohydrate,

    fat, and protein

    metabolism

    Nuts, egg yolk Toxicity: None

    known

    Deficiency: Rare

    Ascorbic acid

    (vitamin C)

    • Antioxidant in

    extracellular fluid

    and lungs

    • Regenerates

    oxidized vitamin E

    • Assists with collagen

    synthesis

    • Enhances immunefunction

    • Assists in synthesis

    of hormones,

    neurotransmitters,

    and DNA

    • Enhances iron

    absorption

    Sweet peppers, citrus

    fruits and juices,

    broccoli,

    strawberries, kiwi

    Toxicity: Nausea and

    diarrhea,

    nosebleeds, increased

    oxidative

    damage, increased

    formation of

    kidney stones in

    people withkidney disease

    Deficiency: Scurvy;

    bone pain

    and fractures,

    depression, and

    anemia

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    Minerals are naturally occurringinorganic (non-carbon-containing)

    substances such as calcium, iron, and

    zinc

    already in the simplest chemical

    form possible and are not digested orbroken down prior to absorption

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    Unlike vitamins, they cannot be synthesized in thelaboratory or by any plant or animal, including

    humans.Minerals are the same wherever they are found,

    whether in soil, a car part, or the human body.

    The minerals in our foods ultimately come from the

    environment; for example, the selenium in soil andwater is taken up into plants and then incorporated

    into the animals that eat the plants

    humans eat the plant foods directly or eat the animalproducts, all of the minerals in our food supply

    originate from Mother Earth!

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    *are those that are required in amounts of

    atleast 100 mg per day.

    *In addition, these minerals are found in thehuman body in amounts of 5 g (5,000 mg)

    or higher.

    *There are seven major minerals: sodium,

    potassium, phosphorus, chloride, calcium,

    magnesium, and sulfur

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    Minerals Functions Food sources Toxicity/

    Deficiency

    Sodium Fluid balance

    Acid–basebalance

    Transmission of

    nerve impulses

    Muscle

    contraction

    Table salt, pickles,

    mostcanned soups,

    snack

    foods, cured

    luncheon

    meats, canned

    tomato

    products

    Toxicity:Water

    retention, highblood pressure,

    loss of calcium

    in urine

    Deficiency: Musclecramps, dizziness,

    fatigue, nausea,

    vomiting,mental confusion

    Potassium  Fluid balance Transmission of

    nerve impulses

    Muscle

    contraction 

    Most fresh fruits

    and

    vegetables:

    potatoes,

    bananas, tomatojuice,

    orange juice,

    melons

    Toxicity : Muscleweakness,

    vomiting,

    irregular heartbeat

    Deficiency: Muscleweakness,paralysis

    , mental

    confusion,irregular

    heartbeat

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    Phosphorus • Fluid balance•

    Bone formation• Component of

    ATP, which

    provides energy

    for our bodies

    Milk/cheese/

    yogurt, soy milkand tofu, legumes

    (lentils, black

    beans), nuts

    (almonds, peanuts

    and peanut

    butter), poultry

    Toxicity: Muscle

    spasms,convulsions,

    low blood calcium

    Deficiency: Muscleweakness,

    muscle damage,

    bone pain,

    dizziness

    Chloride Fluid balance Transmission of

    nerve impulses

    Component of

    stomach acid

    (HCl)  Antibacterial 

    Table salt Toxicity: None

    known

    Deficiency:

    Dangerous blood

    acid –base

    imbalances,irregular

    heartbeat 

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    Calcium Primarycomponent of

    bone

    Acid–base

    balance

    Transmission

    of nerve

    impulses

    Muscle

    contraction

    Milk/yogurt/che

    ese

    (best-absorbed

    form of

    calcium),

    sardines, collard

    greens and

    spinach, calcium

    fortified

    juices

    Toxicity:Mineral

    imbalances,

    shock, kidney

    failure, fatigue,

    mental

    confusion

    Deficiency:Osteoporosis,

    convulsions,

    heart failureMagnesium • Component of

    bone

    • Muscle

    contraction

    •  Assists more

    than 300enzyme

    systems 

    Greens (spinach,

    kale, collard

    greens), whole

    grains, seeds, nuts,

    legumes (navy and

    black beans)

    Toxicity: None

    known

    Deficiency : Low

    blood calcium,

    muscle spasms or

    seizures, nausea,

    weakness,increased risk of

    chronic diseases

    such as heart

    disease,

    hypertension,

    osteoporosis,

    and type 2

    diabetes

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    Sulfur   Component of

    certain B-

    vitamins and

    amino acids

     Acid –base

    balance

    Detoxification

    in liver  

    Protein-rich foods  Toxicity: None

    known

    Deficiency: None

    known 

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    are those we need to consume in amounts

    of less than 100 mg per day. They are

    found in the human body in amounts of lessthan 5 g (5,000 mg).

    Currently, the Dietary Reference Intake

    (DRI) Committee recognizes eight trace

    minerals as essential for human health:selenium, fluoride, iodine, chromium,

    manganese, iron, zinc, and copper

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    Selenium  Required for

    carbohydrate

    and fatmetabolism 

    Nuts, shellfish,

    meat/fish/poultr

    y,whole grains

    Toxicity: Brittle hair

    and nails, skin

    rashes, nausea and

    vomiting,weakness,liver disease

    Deficiency: Specific

    forms of heart

    disease and arthritis,

    impaired immune

    function, muscle pain

    andwasting, depression,

    hostility

    Iodine Synthesis of

    thyroid

    hormones

    Temperatureregulation

    Reproduction

    and growth 

    Iodized salt,

    saltwater

    seafood

    Toxicity: Goiter

    Deficiency:

    Goiter,

    hypothyroidism,cretinism in infant

    of mother who

    is iodine deficient 

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    Iron Component ofhemoglobin in blood

    cells

    Component of

    myoglobin in muscle

    cells

    Assists many

    enzyme systems

    Meat/fish/poultry

    (best-absorbed form of

    iron), fortified cereals,

    legumes, spinach

    Toxicity: Nausea,

    vomiting, and diarrhea;

    dizziness, confusion;

    rapid

    heart beat, organ

    damage, death

    Deficiency: Iron-

    deficiency microcytic

    (small red blood cells),

    Hypochromic anemia

    Zinc Assists more than100 enzyme

    systems

    Immune system

    function Growth and

    sexual

    maturation

    Gene regulation

    Meat/fish/poultry

    (best-absorbed

    form of

    zinc), fortified

    cereals,legumes

    Toxicity: Nausea,

    vomiting, and diarrhea;

    headaches, depressed

    immune

    function, reduced

    absorptionof copper

    Deficiency: Growth

    retardation, delayed

    sexual maturation, eye

    and

    skin lesions, hair loss,

    increased incidenceof illness and infection

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