KLASIFIKASI TUMOR TULANG MENURUT WHO 1993

BYDr. HARDY, SpB

BENIGN INTERMEDIATE MALIGNANT-Osteoma-Osteoid osteoma -Osteoblastoma

-Aggressive (malignant) osteoblastoma

Osteosarcoma-Conventional central-Telangiectatic-Intraosseous well differentiated (low grade)-Round-cell-Parosteal (juxtacortical) -Periosteal-High grade surface

□ Cell Type : Histopatology

Klasifikasi Tumor Tulang menurut WHO 1993

1. Bone-forming tumors

BENIGN MALIGNANT-Enchondroma

-Periosteal (juxtacortical) chondroma

-Solitary osteochondroma

-Multiple hereditary osteochondromas

-Chondroblastoma (epiphyseal chondroblastoma)

-Chondromyxoid fibroma

-Chondrosarcoma

-Juxtacortical (periosteal) chondrosarcoma

-Mesenchymal chondrosarcoma

-Dedifferentiated chondrosarcoma

-Clear cell chondrosarcoma

-Malignant chondroblastoma

2. Cartilage-forming tumors

3. Giant cell tumor (osteoclastoma)

4. Marrow tumors (round cell tumors)

-Ewing sarcoma

-Primitive neuroectodermal tumor of bone (PNET)

-Malignant lymphoma of bone

-Myeloma

BENIGN INTERMEDIATE MALIGNANT

Hemangioma

Lymphangioma

Glomus tumor (glomangioma)

Hemangioendothelioma Hemangiopericytoma

Angiosarcoma

Malignant hemangiopericytoma

5. Vascular tumors

BENIGN INTERMEDIATE MALIGNANT

-Benign fibrous histiocytoma

-Lipoma

-Desmoplastic fibroma -Fibrosarcoma

-Malignant firbrous histiocytoma

-Liposarcoma

-Malignant mesenchymoma

-Leiomyosarcoma

-Undifferentiated sarcoma

5. Vascular tumors

7. Other tumors

-Chordoma

-Adamantinoma of long bones

-Neurilemoma

-Neurofibroma

8. Unclassified tumors

9. Tumor-like lesions

- Solitary bone cyst (simple or unicameral bone cyst)

- Aneurysmal bone cyst

- Juxta-articular bone cyst (intraosseous ganglion)

- Metaphyseal fibrous defect (nonossifying fibroma)

- Eosinophilic granuloma (histiocytosis X, Langerhans cell granulomatosis)- Fibrous dysplasia

- Osteofibrous dysplasia

- Myositis ossificans (heterotopic ossification)

- Brown tumor of hyperparathyroidism

- Intraosseous epidermoid cyst

- Giant cell (reparative) granuloma