DAFTAR ISI - repository.unissula.ac.idrepository.unissula.ac.id/2397/2/daftar isi_1.pdf · vi...
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vi DAFTAR ISI JUDUL ............................................................................................................. i HALAMAN PERSETUJUAN......................................................................... ii SURAT PERNYATAAN................................................................................. iii PRAKATA ....................................................................................................... iv DAFTAR ISI .................................................................................................... vi DAFTAR TABEL ............................................................................................ x DAFTAR DIAGRAM...................................................................................... xi DAFTAR LAMPIRAN .................................................................................... xii INTISARI......................................................................................................... xiii BAB I PENDAHULUAN ........................................................................... 1 1.1. Latar Belakang.......................................................................... 1 1.2. Rumusan Masalah .................................................................... 4 1.3. Tujuan Penelitian ...................................................................... 5 1.4. Manfaat Penelitian .................................................................... 5 BAB II TINJAUAN PUSTAKA .................................................................. 6 2.1. Glaukoma Sudut Terbuka Primer ............................................. 6 2.1.1. Definisi ......................................................................... 6 2.1.2. Etiologi ......................................................................... 7 2.1.3. Gejala dan Tanda .......................................................... 7 2.1.4. Penegakkan Diagnosis .................................................. 10 2.1.4.1. Anamnesis ..................................................... 10
Transcript of DAFTAR ISI - repository.unissula.ac.idrepository.unissula.ac.id/2397/2/daftar isi_1.pdf · vi...
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DAFTAR ISI
JUDUL............................................................................................................. i
HALAMAN PERSETUJUAN......................................................................... ii
SURAT PERNYATAAN................................................................................. iii
PRAKATA....................................................................................................... iv
DAFTAR ISI.................................................................................................... vi
DAFTAR TABEL............................................................................................ x
DAFTAR DIAGRAM...................................................................................... xi
DAFTAR LAMPIRAN.................................................................................... xii
INTISARI......................................................................................................... xiii
BAB I PENDAHULUAN........................................................................... 1
1.1. Latar Belakang.......................................................................... 1
1.2. Rumusan Masalah .................................................................... 4
1.3. Tujuan Penelitian...................................................................... 5
1.4. Manfaat Penelitian.................................................................... 5
BAB II TINJAUAN PUSTAKA.................................................................. 6
2.1. Glaukoma Sudut Terbuka Primer............................................. 6
2.1.1. Definisi ......................................................................... 6
2.1.2. Etiologi ......................................................................... 7
2.1.3. Gejala dan Tanda .......................................................... 7
2.1.4. Penegakkan Diagnosis .................................................. 10
2.1.4.1. Anamnesis ..................................................... 10
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2.1.4.2. Pemeriksaan pada Glaukoma ......................... 11
2.1.5. Penatalaksanaan............................................................ 13
2.1.5.1. Terapi Medis.................................................. 13
2.1.5.2. Teapi Bedah................................................... 13
2.2. Tekanan Intraokuler................................................................. 14
2.2.1. Fisiologi Humor Aquos ................................................ 14
2.2.2. Pengukuran Tekanan Intraokuler.................................. 16
2.2.2.1. Tonometri Metode Langsung ........................ 17
2.2.2.2. Tonometri Metode Tidak Langsung.............. 17
2.2.2.2.1. Tonometer Kontak............................ 18
2.2.2.2.2. Tonometer Nonkontak...................... 19
2.2.2.3. Metode Palpasi .............................................. 20
2.2.3. Pengaturan Tekanan Intraokuler................................... 20
2.2.4. Faktor yang Berpengaruh terhadap Tekanan Intraokuler 21
2.2.4.1. Pengaruh Jangka Panjang .............................. 21
2.2.4.2. Pengaruh Jangka Pendek ............................... 23
2.3. Timolol Maleat ........................................................................ 24
2.3.1. Mekanisme Aksi .......................................................... 25
2.3.2. Farmakokinetik ............................................................. 26
2.3.3. Dosis ............................................................................ 26
2.4. Latanopros ................................................................................ 27
2.4.1. Mekanisme Aksi ........................................................... 28
2.4.2. Farmakokinetik ............................................................ 29
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2.4.3. Dosis ............................................................................. 29
2.5. Kombinasi Tetap Timolol Maleat – Latanopros ...................... 30
2.5.1. Mekanisme Aksi .......................................................... 30
2.5.2. Farmakokinetik ............................................................ 30
2.5.3. Indikasi ......................................................................... 31
2.5.4. Kontraindikasi............................................................... 31
2.5.5. Efek Samping Sistemik................................................. 31
2.5.6. Efek Samping Okuler ................................................... 33
2.6. Kerangka Teori ......................................................................... 34
2.7. Kerangka Konsep ..................................................................... 35
2.8. Hipotesis ................................................................................... 35
BAB III METODE PENELITIAN ................................................................ 36
3.1. Jenis Penelitian....................................................................... 36
3.2. Variabel dan Definisi Operasional ......................................... 36
3.2.1. Variabel Penelitian ..................................................... 36
3.2.2. Definisi Operasional................................................... 36
3.3. Populasi dan Sampel .............................................................. 38
3.3.1. Populasi Penelitian ..................................................... 38
3.3.2. Sampel Penelitian....................................................... 38
3.4. Bahan Penelitian..................................................................... 39
3.5. Cara Penelitian ....................................................................... 39
3.5.1. Tahap Perencanaan..................................................... 39
3.5.1.1. Pengajuan dan Pembuatan Proposal KTI ...... 39
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3.5.1.2. Pengajuan Perijinan Penelitian ...................... 39
3.5.2. Tahap Pelaksanaan ..................................................... 40
3.5.2.1. Pencatatan Data Catatan Medis ....................... 40
3.5.2.2. Pengolahan Data Catatan Medis...................... 40
3.5.3. Alur Penelitian............................................................ 41
3.6. Tempat dan Waktu Peneltian ................................................. 41
3.6.1. Tempat Penelitian....................................................... 41
3.6.2. Waktu Penelitian ........................................................ 42
3.7. Analisis Hasil ......................................................................... 42
BAB IV HASIL PENELITIAN DAN PEMBAHASAN................................. 43
4.1. Hasil Penelitian......................................................................... 43
4.2. Pembahasan .............................................................................. 47
BAB V KESIMPULAN DAN SARAN........................................................... 50
5.1. Kesimpulan............................................................................... 50
5.2. Saran ......................................................................................... 51
DAFTAR PUSTAKA ...................................................................................... 52
LAMPIRAN..................................................................................................... 56
