Post on 24-Apr-2023
Throughout my career as a Hematopathologist, I have been passionate about volunteering for professional societies, in various areas of education, professional development and advocacy. In my clinical practice, I had the opportunity to serve as medical director for clinical flow cytometry laboratories, at academic institutions and reference laboratories, for more than a decade, and to oversee laboratory test development in a complex regulatory environment. At the same time, I had the privilege of overseeing or contributing to professional development activities by working with several major professional societies (ASCP, CAP, SH and ICCS). For the past several years, I volunteered as a member of the ICCS Education Committee and also chaired the e-learning subcommittee. More recently, I became a member of the Advocacy and Outreach Committees at ICCS and will be co-chairing the Advocacy session at this year’s ICCS annual meeting. In addition to my work with these committees, I am also an ad-hoc contributor to the Newsletter, Q&A and Video subcommittees of the ICCS.
Over the years, my strong interest in understanding the complex regulatory landscape, as it pertains to the clinical laboratory practice, and desire in promoting our profession to ensure a robust current and future pathology workforce, have provided me with the necessary background for continuing in a similar role at ICCS. Therefore, I would be honored and delighted to serve as a Senior Councilor for Advocacy for the Society.
Horatiu Olteanu - Statement of Interest
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Curriculum Vitae and Bibliography
Horatiu Olteanu, MD, PhD
Personal Information Place of Birth: Medias, Romania Citizenship: United States of America Email Address: Olteanu.Horatiu@mayo.edu
Present Academic Rank and Position
Co-Director - Cell Kinetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic
11/2018 - Present
Professor of Laboratory Medicine and Pathology - Mayo Clinic College of Medicine and Science
02/2019 - Present
Consultant - Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota
02/2021 - Present
Education Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania - MD, Doctorate of Medicine
09/1990 - 09/1996
"Nicolae Stancioiu" Heart Institute, Cluj-Napoca, Romania - Internship, Cardiothoracic Surgery
04/1997 - 03/1998
Robert Koch Hospital, Gehrden, Germany - Visiting Fellow, Cardiovascular Diseases Clinic
04/1998 - 06/1998
University of Nebraska Lincoln, Lincoln, Nebraska - Ph.D., Biochemistry 07/1998 - 06/2003
University of Texas Southwestern Medical Center, Dallas, Texas - Resident, Anatomic and Clinical Pathology
07/2003 - 06/2007
Medical College of Wisconsin Affiliated Hospitals, Milwaukee, Wisconsin - Fellow, Hematopathology
07/2007 - 06/2008
Certification
Board Certifications
American Board of Pathology Anatomic Pathology and Clinical Pathology 2007 - Present
Anatomic Pathology and Clinical Pathology/Hematology 2008 - Present
Licensure Kansas 0432133 (inactive) (Medical) 2006 - Present
Wisconsin 50870-020 (Medical) 2007 - Present
Minnesota 62881 (Medical) 2017 - Present
Honors and Awards Eli Lilly-Alsifcom Award for Outstanding Academic Performance - "Iuliu Hatieganu" University of Medicine and Pharmacy
05/1996
Milton E. Mohr Graduate Fellowship - University of Nebraska - Lincoln, Lincoln, Nebraska
03/2000
Bukey Memorial Graduate Fellowship - University of Nebraska - Lincoln, Lincoln, Nebraska
03/2001
Holling Family Teaching Assistant Award - University of Nebraska - Lincoln, Lincoln, Nebraska
03/2002
Predoctoral Fellowship - American Heart Association , Lincoln, Nebraska 01/2003
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Folsom Distinguished Dissertation Award - University of Nebraska - Lincoln, Lincoln, Nebraska
05/2004
Third Place - Podium Competition, John R. Rainey, MD Residents'/Fellow's Seminar - Texas Society of Pathologists Annual Meeting
01/2007
MCW Outstanding Medical Student Teacher for 2008-2009 Pathology Course - Medical College of Wisconsin
12/2009
Distinguished Biochemistry Alumni Award - University of Nebraska - Lincoln, Lincoln, Nebraska
04/2013
Outstanding Faculty Service Award - Medical College of Wisconsin 08/2013
Previous Professional Positions and Major Appointments Hospital Staff - Children's Hospital of Wisconsin, Wauwatosa, Wisconsin 07/2008 - 02/2011
Assistant Professor of Pathology - Medical College of Wisconsin, Milwaukee, Wisconsin
07/2008 - 06/2012
Hospital Staff - Community Memorial Hospital, Menomonee Falls, Wisconsin 07/2008 - 02/2018
Hospital Staff - Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin 07/2008 - 02/2018
Medical Director - Diagnostic Flow Cytometry Laboratory - Wisconsin Diagnostic Laboratories, Milwaukee, Wisconsin
09/2008 - 02/2018
Flow Cytometry Rotation Director, Pathology Residency Program - Medical College of Wisconsin, Milwaukee, Wisconsin
07/2011 - 02/2018
Program Director, Hematopathology Fellowship - Medical College of Wisconsin, Milwaukee, Wisconsin
07/2011 - 02/2018
Hematopathology Rotation Director, Pathology Residency Program - Medical College of Wisconsin, Milwaukee, Wisconsin
07/2011 - 02/2018
Associate Professor of Pathology - Medical College of Wisconsin, Milwaukee, Wisconsin
07/2012 - 02/2018
Hospital Staff - St. Joseph's Hospital, West Bend, Wisconsin 07/2012 - 02/2018
Medical Director, Continuing and Professional Education - Medical College of Wisconsin, Milwaukee, Wisconsin
07/2016 - 02/2018
Hospital Staff - Children's Hospital of Wisconsin, Wauwatosa, Wisconsin 03/2017 - 02/2018
Senior Associate Consultant - Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota
02/2018 - 02/2021
Professional Memberships and Societies
Professional Memberships and Services
American Chemical Society Member 01/2000 - 12/2011
American Medical Association Member 07/2008 - 12/2010
American Society for Clinical Pathology Member 01/2005 - Present Pathologist Recertification Individualized Self-Assessment Examination (PRISE) Committee
Member 09/2009 - 09/2013 Chair 09/2013 - 12/2018
Association for Molecular Pathology Member 01/2020 - Present
College of American Pathologists Member 01/2005 - Present
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Hematology and Flow Cytometry Laboratory Inspector 05/2006 - Present House of Delegates Alternate Member 04/2020 - Present Hematology and Clinical Microscopy Resource Committee (HCMRC)
Member 11/2015 - Present International Clinical Cytometry Society
Member 01/2014 - Present Advocacy Committee Member 03/2020 - Present Outreach Committee Member 03/2020 - Present 2016 Annual Meeting Program Committee
Member 01/2016 - 12/2016 2017 Annual Meeting Program Committee
Member 01/2017 - 12/2017 E-Learning Subcommittee
Chair 01/2016 - 12/2019 Education Committee
Member 12/2015 - 12/2019 International Society for Advancement of Cytometry
Member 01/2014 - Present Minnesota Medical Association
Member 07/2018 - Present North Texas Society of Pathologists
Member 01/2006 - 06/2007 Phi Lambda Upsilon, Chemical Honor Society
Member 01/2000 - 06/2003 Society for Academic Continuing Medical Education
Member 01/2016 - Present Annual Meeting Abstract Review Committee
Member 09/2016 - 12/2016 Society for Hematopathology
Member 01/2009 - Present Case of the Quarter (COQ)
Co-Chair 03/2013 - 03/2015 Chair 03/2015 - 03/2017
Education Committee Member 03/2013 - 03/2015
Texas Society of Pathologists Member 11/2003 - 06/2007
United States and Canadian Academy of Pathology Member 01/2005 - Present USCAP Annual Meeting Abstract Review Board, Hematopathology Section
Member 06/2015 - 10/2017 Zumbro Valley Medical Society
Member 07/2018 - Present
Journal Responsibilities
Journal Editorial Responsibilities
Laboratory Medicine Assistant Editor 08/2015 - 04/2019 Associate Editor 05/2019 - Present
Journal Other Responsibilities
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Annals of Diagnostic Pathology Reviewer 04/2013 - Present
BMC Hematology Reviewer 01/2014 - Present
Clinical Case Reports Reviewer 01/2014 - Present
Clinical Chemistry and Laboratory Medicine Reviewer 04/2013 - Present
Clinical Epidemiology Reviewer 06/2013 - Present
Cytometry. Part B, Clinical Cytometry Reviewer 04/2013 - Present
Haematologica Reviewer 03/2009 - Present
International Journal of Laboratory Hematology Reviewer 07/2014 - Present
Journal of Clinical Laboratory Analysis Reviewer 10/2013 - Present
Journal of Hematology & Oncology Reviewer 09/2013 - Present
Laboratory Medicine Reviewer 03/2009 - Present
Oncotarget Reviewer 06/2015 - Present
Plos One Reviewer 08/2016 - Present
Education Interests and Accomplishments
Curriculum and Course Development Pathology reviews and updates: Benign Leukocyte Disorders Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Pathology reviews and updates: Myelodysplastic Syndromes Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Pathology reviews and updates: Acute Myeloid Leukemia Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Pathology reviews and updates: Acute Lymphoblastic Leukemia Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Pathology reviews and updates: Common Diagnostic Patterns by Flow Cytometry Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Pathology reviews and updates: Benign and Reactive Lymphadenopathies Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Pathology reviews and updates: Low-Grade B-cell Lymphomas I Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
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Pathology reviews and updates: Low-Grade B-cell Lymphomas II Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Hematopathology I AP/CP resident assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin
2011 - 2018
Hematopathology II AP/CP resident assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin
2011 - 2018
Flow Cytometry AP/CP resident assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin
2011 - 2018
Hematopathology Fellowship Diagnostic bone marrow and lymph node assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin
2011 - 2018
Hematopathology Fellowship Flow cytometry assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin
2011 - 2018
Applications of Flow Cytometric Immunophenotyping for Medical Technologists Medical College of Wisconsin Milwaukee, Wisconsin
2015 - 2018
Teaching Biochemistry 433/833 Teaching assistant; 1 semester/year University of Nebraska - Lincoln Lincoln, Nebraska
1999 - 2001
Sophomore Pathology Course Small group discussion leader; 6 hours/year University of Texas Southwestern Medical Center Dallas, Texas
2006 - 2007
Pathology reviews and updates: Low-Grade B-cell Lymphomas I and II 2 hours/year microscope sessions; AP/CP Pathology residency program Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Unknown Slide Case Review 4 hours/year microscope sessions; AP/CP Pathology residency program Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
Pathology reviews and updates: Benign Leukocyte Disorders, Myelodysplastic Syndromes, Myeloproliferative Neoplasms, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Common Diagnostic Patterns by Flow Cytometry 6 hours/year lectures; AP/CP Pathology residency program Medical College of Wisconsin Milwaukee, Wisconsin
2008 - 2018
MCW M2 Medical Student Pathology Course: Reactive Leukocyte Disorders 1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin
2009 - 2012
MCW M2 Medical Student Pathology Course: Myelodysplastic Syndrome and Myleoproliferative Neoplasms
2009 - 2012
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1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin
MCW M2 Medical Student Pathology Course: Acute Myeloid Leukemia 1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin
2009 - 2012
MCW M2 Medical Student Pathology Course: Acute Lymphoblastic Leukemia 1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin
2009 - 2012
MCW M2 Pathways Hematology Module: Introduction to WBC Disorders, Reactive and Neoplastic Myeloid Processes, Targeted Leukemia Therapy 4 hours of lectures and team-based learning activities/year Medical College of Wisconsin Milwaukee, Wisconsin
2013 - 2018
Hematopathology Fellows 1 hour/week; Slide teaching/case signout Mayo Clinic Rochester, Minnesota
2018 - Present
Hematopathology rotating residents 5 hours/week; Slide teaching/case signout Mayo Clinic Rochester, Minnesota
2018 - Present
Academy of Educational Excellence
Excellence in Education Administration and Leadership at the Fellow level on this date June 2019
Mentorship Spears, Michael (Fellow) Description: Current Status: Staff Pathologist, Pathology Associates, Greenville, TX Outcome: Co-authored 3 abstracts; 3 poster presentations at international meetings (USCAP); co-authored 3 published research manuscripts
07/2008 - 06/2009
Davidson-Keup, Anna (Pre-Med Student) Description: UW-Milwaukee Pre-Med School Mentoring Program Current Status: Not known Outcome: Career advice
12/2008 - 01/2009
Vaughan, James (Resident and Fellow) Description: Current Status: Assistant Professor of Pathology, University of Tennessee Graduate School of Medicine, Knoxville, TN Outcome: Co-authored 8 abstracts; 8 poster presentations at national and international meetings (USCAP, ASCP); co-authored a published research manuscript; developed tissue microarray for SOX-11 antibody validation (first laboratory in the state of Wisconsin)
07/2009 - 06/2012
Horna, Pedro (Clinical Fellow) Description: Current Status: Consultant and Associate Professor of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Outcome: Co-authored 2 abstracts; 2 poster presentations at international meetings (USCAP); co-authored a published research manuscript
07/2010 - 06/2011
Buonaccorsi, Noelle (Resident) Description: Current Status: Staff Pathologist, OSF HealthCare, Peoria, IL Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP); co-authored a published research manuscript
07/2010 - 06/2011
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Wilcox, Rebecca (Junior Faculty) Description: Current Status: Associate Professor of Pathology, University of Vermont College of Medicine, Burlington, VT Outcome: Co-authored 3 oral presentations at national meetings (ASCP); committee service for national Pathology organization (ASCP)
07/2010 - 06/2015
Plaza, Jose (Junior Faculty) Description: Current Status: Professor of Pathology and Dermatology, Ohio State University Wexner Medical Center, Columbus OH Outcome: Co-authored 3 oral presentations at national meetings (ASCP); co-authored a published research manuscript; committee service for national Pathology organization (ASCP)
07/2010 - 06/2016
Lloyd, Isaac (Medical Student) Description: Pathway mentor Current Status: Adjunct Assistant Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT Outcome:
10/2010 - 06/2012
Schumann, Joseph (Medical Student) Description: Pathway research mentor Current Status: Staff Physician, Ascension Medical Group, Greenville, WI Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP)
10/2010 - 06/2012
Parsons, Lauren (Resident) Description: Current Status: Assistant Professor of Pathology, Medical College of Wisconsin, Milwaukee, WI Outcome: Co-authored 2 abstracts and 2 poster presentations at international meetings (USCAP, ICCS); committee service for national Pathology organization (ASCP)
07/2012 - 06/2015
Batdorf, Bjorn (Resident and Fellow) Description: Current Status: Staff Pathologist, North Memorial Medical Center, Minneapolis, MN Outcome: Co-authored 6 abstracts and 6 poster presentations at national and international meetings (USCAP, ASCP, ICCS); co-authored 1 published research manuscript
01/2013 - 02/2018
Drobysheva, Anastasia (Visiting Fellow) Description: Visiting fellow mentor Current Status: Anatomic and Clinical Pathology Resident, UT Southwestern Medical Center, Dallas, TX Outcome:
05/2013
Hosking, Paul (Junior Faculty) Description: Current Status: Assistant Professor, University of Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY Outcome: Co-authored 12 abstracts and 12 poster presentations at national and international meetings (USCAP, ASCP); co-authored 5 published research manuscripts
07/2013 - Present
Hongmei, Li (Resident) Description: Current Status: Staff Pathologist, Quest Diagnostics/AmeriPath, Milwaukee, WI Outcome: Co-authored 2 abstracts and 2 poster presentations at international meetings (USCAP); co-authored 1 published research manuscript
07/2013 - 06/2016
Schelling, Lindsay (Fellow) Description: Current Status: Staff Pathologist, OSF Saint Anthony Medical Center, Rockford, IL Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP); co-authored 2 published manuscripts
07/2014 - 06/2015
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Robin, Adam (Resident) Description: Current Status: Staff Pathologist, London, UK Outcome: Co-authored 2 abstracts and 2 poster presentations at international meetings (USCAP, SH/EAHP)
07/2014 - 06/2016
Gibson, Sarah (Junior Faculty) Description: Current Status: Associate Professor of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA Outcome: Committee service for national Pathology organization (Society for Hematopathology)
07/2014 - 06/2017
Hartley, Christopher (Resident) Description: Current Status: Senior Associate Consultant and Assistant Professor of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP); co-authored one published manuscript; committee service for national Pathology organization (ASCP)
07/2014 - 06/2018
Hintzke, Maria (Resident and Fellow) Description: Current Status: Staff Pathologist, Ochsner Health System, New Orleans, LA Outcome: Co-authored 5 abstracts and 5 poster presentations at national and international meetings (USCAP, ASCP, SH/EAHP)
07/2015 - 06/2016
Peterson, Jess (Junior Faculty) Description: Current Status: Consultant and Associate Professor of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Outcome: Co-authored 5 published research manuscripts
07/2015 - 06/2018
Foss, Halle (Medical Student) Description: Pathway research mentor Current Status: Medical Student, Medical College of Wisconsin, Milwaukee, WI Outcome:
10/2015 - 01/2016
Knous, Kort (Medical Student) Description: Global Health Scholarly Pathway Advisor and research mentor Current Status: Medical Student, Medical College of Wisconsin, Milwaukee, WI Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP)
12/2015 - 06/2017
Academic Career Development Preparing Future Faculty Fellow University of Nebraska - Lincoln Lincoln, Nebraska
09/2001 - 05/2002
GME: The New Frontier MCWAH 2012 GME Retreat Medical College of Wisconsin, Wisconsin
10/2012
ASCP Spring Leadership Forum 2013 American Society for Clinical Pathology Miami, Florida
03/2013
Developing effective team-based learning and case-based learning modules Discovery Curriculum faculty meeting Medical College of Wisconsin, Wisconsin
05/2015
Increasing fatigue awareness and recognizing sleep deprivation in faculty and trainees Pathology Grand Rounds Medical College of Wisconsin, Wisconsin
08/2015
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Giving effective and timely feedback to trainees Pathology Grand Rounds Medical College of Wisconsin, Wisconsin
05/2016
Effective milestone mapping, assessment and implementation for the Hematopathology fellowship Hematopathology Clinical Competency Committee meeting Medical College of Wisconsin, Wisconsin
08/2016
Curriculum development and self-assessment module evaluation for the 9th Annual Midwestern Conference 9th Annual Midwestern Conference: Update Course on Surgical Pathology Medical College of Wisconsin, Wisconsin
10/2016 - 10/2016
Pathways to Success and Vitality: Resilience and Growth MCW Faculty Career Development Committee meeting Medical College of Wisconsin, Wisconsin
03/2017
Society for Academic Continuing Medical Education 2017 SACME Annual Meeting Scottsdale, AZ, United States of America
05/2017 - 05/2017
Continuing education outcomes assessment MCW CME committee meeting Medical College of Wisconsin, Wisconsin
08/2017
Identifying and managing fatigue and burnout among learners Pathology Grand Rounds Medical College of Wisconsin, Wisconsin
08/2017
Effective milestone assessment and mapping strategies Clinical Pathology Division Meeting Medical College of Wisconsin, Wisconsin
08/2017
Developing clinically relevant learning outcomes Pathology Grand Rounds committee meeting Medical College of Wisconsin, Wisconsin
09/2017
Curriculum development and self-assessment module evaluation for the 10th Annual Midwestern Conference 10th Annual Midwestern Conference: Update Course in Surgical Pathology Medical College of Wisconsin, Wisconsin
09/2017 - 09/2017
Are conventional learning theories sufficient to guide multi-site complex educational interventions? SACME Virtual Journal Club
03/2018
Implications of UME and GME Outcomes-based Reform Efforts for CPD SACME Virtual Journal Club
04/2018
ASCP Spring Leadership Forum 2018 American Society for Clinical Pathology Miami, Florida
04/2018
The Practice and Improvement Gaps in Medical Practice and Medical Education: Insights from Implementation Science SACME Virtual Journal Club
05/2018
DLMP Faculty 15 - Wellness Hematopathology Education Oversight Committee Meeting Rochester, Minnesota
09/2018
DLMP Faculty 15 - Writing Effective Multiple Choice Questions Hematopathology Education Oversight Committee Meeting Rochester, Minnesota
10/2018
DLMP Faculty 15 - Active Learning Hematopathology Division Meeting
11/2018
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DLMP Faculty 15 - Poll Everywhere Education Oversight Committee Meeting Rochester, Minnesota
12/2018
Trainees' Perceptions of Feedback: Validity Evidence for Two FEEDME (Feedback in Medical Education) Instruments Education Science Journal Club Rochester, Minnesota
02/2019
Striving While Accepting: Exploring the Relationship Between Identity and Implicit Bias Recognition and Management Education Science Journal Club Rochester, Minnesota
03/2019
Data, Big and Small: Emerging Challenges to Medical Education Scholarship Education Science Journal Club Rochester, Minnesota
04/2019
DLMP Faculty 15 - Discussion & Inquiry Hematopathology Division Meeting
04/2019
Immuno-Oncology (IO) Change Makers Discussion Group and Leadership Cohort American Society for Clinical Pathology CME Program Chicago, Illinois
04/2019 - 06/2019
Exploring the relationship between examiners' memories for performances, domain separation and score variability. Education Science Journal Club Rochester, Minnesota
05/2019
Comparing resident – patient encounters and case presentations in a family medicine clinic. Education Science Journal Club Rochester, Minnesota
08/2019
Integrating Technology into Teaching: From the Big Auditorium to the Bedside. ACGME webcast Rochester, Minnesota
08/2019
Unconscious Bias Hematopathology Division Meeting
11/2019
Beyond the United States Medical Licensing Examination Score: Assessing Competence for Entering Residency. Education Science Journal Club Rochester, Minnesota
11/2019
Crucial Conversations Mayo Clinic Rochester, Minnesota
11/2019
It’s a Story, not a Study: How to write your medical education research so people will want to read it. Education Science & Scholarship Symposium Rochester, Minnesota
12/2019
Quantitative Data Analysis for Education Researchers: Fundamentals, Tips, and Tricks Education Science & Scholarship Symposium Rochester, Minnesota
12/2019
Whose work is it anyway? Teamwork, collective competence, and the myth of individual performance assessment Education Grand Rounds Rochester, Minnesota
12/2019
Cognition, Mindsets and Well-Being ACGME Grand Rounds webinar Rochester, Minnesota
01/2020
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DLMP Faculty 15: Writing Letters of Reference for Residents and Fellows Hematopathology Division Meeting Rochester, Minnesota
01/2020
Education Science Journal Club Education Science Journal Club Rochester, Minnesota
01/2020
DLMP Faculty 15: Social Media - Twitter Hematopathology Division Meeting Rochester, Minnesota
02/2020
Education & Technology Forum 2020 Education & Technology Forum 2020 Rochester, Minnesota
02/2020
Education Science Journal Club Education Science Journal Club Rochester, Minnesota
02/2020
Education Grand Rounds: Validation of learner assessments: State of the art and future directions Education Grand Rounds Rochester, Minnesota
02/2020
ASCP Spring Leadership Forum 2020 American Society for Clinical Pathology Miami, Florida
03/2020 - 04/2020
Education Grand Rounds: Assessing Clinical Reasoning: Simulation and Beyond Dr. Rachel Yudkowsky as the 2020 Simulation Center Visiting Professor: Education Grand Rounds: Assessing Clinical Reasoning: Simulation and Beyond Rochester, Minnesota
04/2020
Faculty/Staff Development Series - 'COVID-19 and Wellbeing: Lessons learnt and Moving Forward'- Zoom Meeting COVID -19 led to enhanced wellbeing resources being made available for staff, trainees and faculty in the face of emerging stressors. The continued pandemic, and projected post pandemic phase heightens the need to review and strengthen wellbeing related interventions. This session will focus on:•Reviewing what helped you and your trainees to cope. •Sharing themes that have emerged in emerging empirical studies on mental health effects of COVID-19. •Brainstorming what can be done/offered in future at the programmatic and individual level.•Review of some cognitive and emotional tools to enhance resiliency. Rochester, Minnesota
06/2020
Crossing the Virtual Chasm: Rethinking Curriculum, Competency, and Culture in the Virtual Care Era Rochester, Minnesota
09/2020
Education Science Journal Club Social and Scholarship Hour Rochester, Minnesota
10/2020
Education Grand Rounds: Pivots in Health Professions Education: Advancing and Enhancing our Learning Environment Learn about Telehealth Education, Advancing Digital Engagement, Equity, Diversity, Inclusion, and Anti-Racism Curriculum Rochester, Minnesota
10/2020
Education Science Journal Club Rochester, Minnesota
11/2020
Education Grand Rounds: Emerging Online Learning Trends for Health Professional Education
11/2020
Education Grand Rounds Education Science and Scholarship Symposium (ESSS) Rochester, Minnesota
12/2020
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Education Science Journal Club & ESSS Education Science Journal Club & ESSS Rochester, Minnesota
12/2020
ESSS | Poster & Works In Progress Session ESSS | Poster & Works In Progress Session Rochester, Minnesota
12/2020
Education and Technology Forum 2021 - Mayo Clinic Education and Technology Forum 2021 Rochester, Minnesota
02/2021
2021 Findling Lecture: Education Scholarship Event- Mayo Clinic 2021 Findling Lecture: Education Scholarship Event- Mayo Clinic Rochester, Minnesota
02/2021 - 02/2021
Fundamentals for Medical Education (Fun 4 ME) Fundamentals for Medical Education (Fun 4 ME) is designed for health care professionals either new to educationor who have some experience and are looking to hone their skills, reinforce best practices, and learnnew strategies within health professions, education, and assessment. Mayo Clinic Academy of Educational Excellence Professional Development Rochester, Minnesota
08/2021 - 08/2021
2021 Annual Association for Medical Education in Europe (AMEE): The Virtual Conference- Redefining Health Professions Education Together The AMEE conference is the leading annual event for all involved in medical and healthcare professions education. 2021 AMEE: The Virtual Conference- Redefining Health Professions Education Together Rochester, Minnesota
08/2021 - 08/2021
Educational Activities Innovative activities for resident/other trainee education in Hematopathology: 1) Created curriculum and evaluations based on new ACGME milestones for Hematopathology I, Hematopathology II, and Flow Cytometry AP/CP residency rotations, 2) Provided and created proficiency testing (PT) boot camp education for first year AP/CP residents, 3) Created Flow Cytometry trainee education modules, 4) Developed Hematopathology and Flow Cytometry examination, 5) Created Hematology/Flow Cytometry/Coagulation laboratory rounds for residents and fellows, 6) Provide education to a variety of individuals including pathology residents, Hematopathology fellows, Surgical Pathology fellows, other subspecialty pathology fellows, Hematology/Oncology fellows, medical students, Pathology observers, and laboratory professionals. Innovative activities for the Hematopathology Fellowship include: 1) Implemented Fellowship milestones July 2016, 2) Performed gap analysis of Hematopathology fellowship program, 3) Developed and implemented new rotation evaluations to align with ACGME milestones, 4) Formed Hematopathology Clinical Competency Committee (CCC), 5) Created and implemented formal fellow orientation with manual (over 50 type-written pages) 6) Developed Hematopathology fellowship employer survey, 7) Created transitions of care policy for Hematopathology fellows, 8) Created graduated (progressive) responsibility management policy for Hematopathology fellows, 9) Updated internal and external Hematopathology fellowship websites. Other innovative activities include: 1) Developed and implemented four Hematopathology-related modules (General Hematopathology, Bone Marrow, Lymph Node and Spleen, Flow Cytometry) for the Pathologist Recertification Individualized Self-Assessment Examination (PRISE) committee of the American Society for Clinical Pathology (ASCP); this is an online, modular, personal self-assessment, and comprehensive education tool specifically designed for practicing pathologists and Pathology residents, 2) Contributed personally 357 multiple choice questions to the 2011-2017 PRISE modules, 3) Developed and implemented a novel interactive format with CME and self-assessment module (SAM) credits for the Case of the Quarter e-learning activity of the Society for Hematopathology (SH), 4) Developed and implemented a novel format of e-learning activities for the International Clinical Cytometry Society (ICCS), 5) Developed and reviewed educational material, and submitted annual audit evaluations to the American Board of Pathology (ABP) to maintain the status of approved SAM provider for the MCW Department of Pathology, 6) Formed a formal MCW Pathology Grand Rounds committee as a venue to oversee, discuss, implement and continuously improve and innovate the delivery of Pathology education, 7) Re-organized and chaired the MCW CME committee, that developed and implemented a critical Responsible Opioid Prescribing Guideline CE course required by the state of Wisconsin Medical Board; developed and implemented new application guidelines for recurring CE activities, to better align with ACCME requirements; developed new outcome assessment tools and evaluations for CE activities, to better align with departmental and
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institutional quality indicators; implemented a major upgrade of EthosCE, the MCW institutional learning management platform; developed the first major strategic planning initiative for the Office of Continuing and Professional Education at MCW to map out the needs of its learners as it transforms into a health sciences university.
Institutional/Departmental Administrative Responsibilities, Committee Memberships and Other Activities
Mayo Clinic
DLMP Portfolio Prioritization Panel Member 06/2018 - Present
DLMP SoftFlow Oversight Subcommittee Member 09/2019 - Present
Education Oversight Committee, Division of Hematopathology Member 03/2018 - Present
Mayo Clinic in Rochester
Department of Laboratory Medicine and Pathology Division of Hematopathology
Myeloid Working Group Chair 07/2019 - Present
Activities at Other Institutions
Medical College of Wisconsin (MCW) Clinical Competency Committee, MCW Hematopathology Fellowship
Chair 03/2015 - 02/2018 Continuing Medical Education Committee, MCW Faculty Council
Member 07/2011 - 06/2014 Member 06/2015 - 06/2016
Faculty Climate Focus Group Member 06/2011
Grand Rounds Committee, MCW Department of Pathology Chair 04/2016 - 02/2018
Hematologic Malignancy Conference, MCW Department of Pathology Activity Director 11/2011 - 02/2018
Hematopathology Faculty Search Committee Member 05/2013 - 06/2013 Member 05/2016 - 12/2016
Institutional Review Board Committee #2 Ad Hoc Member 06/2014 - 02/2018
Institutional Review Board Committee #4 Member 01/2011 - 02/2018
Internal Review of the MCWAH Family Medicine - St. Joseph's Residency Program
Member 10/2012 - 11/2012 Internal Review of the MCWAH Hematology/Oncology Fellowship Program
Member 01/2008 MCW Cancer Center
Member 06/2011 - 02/2018 MCW Continuing Medical and Professional Education Committee
Chair 07/2016 - 02/2018 Medical College of Wisconsin, Institutional Review Board Committee #2
Ad Hoc Member 06/2016 - 02/2018
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Wisconsin Diagnostic Laboratories Capital Steering Committee
Member 03/2012 - 02/2018 Communications Committee
Member 03/2014 - 12/2016 Dyad Operations Committee
Member 09/2011 - 02/2018 Quality Committee
Member 04/2017 - 02/2018
Presentations Extramural National or International
Invited
Reductive activation of methionine synthase: Purification and characterization of mammalian methionine synthase reductase FASEB Summer Research Conference "Folic Acid, Vitamin B12 and One Carbon Metabolism" Snowmass, Colorado
08/05/2000 - 08/10/2000
Effects of common polymorphisms on the activation of methioninesynthase by the dual flavoprotein oxidoreductase,methionine synthase reductase Gordon Research Conference " Enzymes , Coenzymes and Metabolic Pathways" Meriden, New Hampshire
07/20/2002 - 07/27/2002
Inflammatory Pseudotumor of Lymph Node Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
09/12/2008 - 09/14/2008
Blastic Plasmacytoid Dendritic Cell Neoplasm Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
08/21/2009 - 08/23/2009
Histiocytic Sarcoma Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
08/21/2009 - 08/23/2009
Flow Cytometry of Hodgkin Lymphoma Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
05/14/2010 - 05/16/2010
Case Study Interpretations 25th Annual International Clinical Cytometry Society Meeting Houston, Texas
10/03/2010 - 10/05/2010
Diffuse Large B-Cell Lymphoma: An Update on New Entities The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
09/09/2011 - 09/11/2011
Flow Cytometric Analysis in Myeloid Neoplasms 2011 ASCP Annual Meeting I WASPaLM XXVI World Congress Las Vegas, Nevada
10/19/2011 - 10/22/2011
Immunodeficiency-Associated Lymphoproliferative Disorders The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
09/14/2012 - 09/16/2012
Horatiu Olteanu, MD, PhD
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Splenic Lymphomas: Classification and Advances in the Separation of Distinct Clinic pathologic and Molecular Entities -A SH/EAHP Workshop Proposal 2013 USCAP Annual Meeting Baltimore, Maryland
03/02/2013 - 03/08/2013
Maintenance of Certification and PRISE: Applying New and Validated Knowledge to Clinical Practice 2013 ASCP Annual Meeting Chicago, Illinois
09/18/2013 - 09/21/2013
Diagnostic Pitfalls in Reactive and Malignant Lymphadenopathies The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
09/20/2013 - 09/22/2013
Normal and Abnormal Immunophenotype Patterns by Flow Cytometry 2014 ASCP Annual Meeting Tampa, Florida
10/08/2014 - 10/10/2014
Problem Areas in the Interpretation of Lymph Node, Cutaneous, and Gastrointestinal l Biopsies - Presented by the Faculty of PRISE 2014 ASCP Annual Meeting Tampa, Florida
10/08/2014 - 10/10/2014
Diagnostic Challenges in Low-Grade B-Cell Lymphomas 2015 CAP Annual Meeting Nashville, Tennessee
10/04/2015 - 10/07/2015
Advanced Flow Cytometry-Based Diagnostic Hematopathology: An Integrated Approach 2015 ICCS Annual Meeting Denver, Colorado
10/11/2015 - 10/13/2015
Diagnostic Challenges in Low-Grade B-Cell Lymphomas 2016 CAP Annual Meeting Las Vegas, Nevada
09/25/2016 - 09/28/2016
Reactive Lymphoid Lesions vs. Low-Grade Lymphomas in Bone Marrow 2016 CAP Annual Meeting Las Vegas, Nevada
09/25/2016 - 09/28/2016
Advanced Flow Cytometry-Based Diagnostic Hematopathology 2016 ICCS Annual Meeting Bonita Springs, Florida
09/30/2016 - 10/04/2016
Have a Problem? Ask an Expert 2016 ICCS Annual Meeting Bonita Springs, Florida
09/30/2016 - 10/04/2016
38 Year-Old Patient with Extensive Lymphadenopathy Slide seminar: Problem Cases in Surgical Pathology The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
10/14/2016 - 10/16/2016
Diagnostic Challenges in CD5 (+) Low-Grade B-Cell Lymphomas The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
10/14/2016 - 10/16/2016
Clinical and Pathologic Features of Aggressive B-cell Lymphomas MEDLAB America Congress Orlando, Florida
08/08/2017 - 08/10/2017
Improving Efficiency in the Hematology Laboratory MEDLAB America Congress Orlando, Florida
08/08/2017 - 08/10/2017
Horatiu Olteanu, MD, PhD
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Molecular Diagnosis in Complex Hematopathology Cases The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin
09/15/2017 - 09/17/2017
Diagnostic Challenges in Low-Grade B-Cell Lymphomas 2017 CAP Annual Meeting National Harbor, Maryland
10/08/2017 - 10/11/2017
Diagnostic Challenges in Low-Grade B-Cell Lymphomas: Morphologic and Immunophenotypic Variants of CD5(+) Lymphoproliferative Disorders 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii
09/23/2019 - 09/27/2019
Diagnostic Challenges in Low-Grade B-Cell Lymphomas: Morphologic and Immunophenotypic Variants of Follicular Lymphoma 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii
09/23/2019 - 09/27/2019
Flow Cytometric Diagnosis of Complex Hematopathology Cases 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii
09/23/2019 - 09/27/2019
Flow Cytometric Evaluation of Mature T and NK-Cell Neoplasms: Integrating Morphology, Immunophenotype and Cytogenetic/Molecular Findings 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii
09/23/2019 - 09/27/2019
Flow Cytometric Evaluation of Plasma Cell Dyscrasias 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii
09/23/2019 - 09/27/2019
Flow Cytometry of Lymphoblastic Leukemias and Acute Leukemias of Ambiguous Lineage 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii
09/23/2019 - 09/27/2019
Quality Parameters for Flow Cytometric Minimal Residual Disease (MRD) Assessment in Plasma Cell Neoplasms. 2020 USCAP Annual Meeting Los Angeles, California
02/29/2020 - 03/05/2020
Training Physician Extenders in the Clinical Practice of Diagnostic Hematopathology: A Novel Approach to Building Expertise and Improving Quality and Efficiency. 2020 USCAP Annual Meeting Los Angeles, California
02/29/2020 - 03/05/2020
Oral
Comparative Evaluation of Flow Cytometry (FC) and Morphology for Detecting Malignant Cells in Cerebrospinal Fluid (CSF) from Patients with Known Hematologic Neoplasms 2019 USCAP Annual Meeting National Harbor, Maryland
03/16/2019 - 03/21/2019
Single Antibody Assessment of T-Cell Clonality by Flow Cytometry Rapidly Identifies T-Cell Neoplasms and Monotypic CD8-Positive Subset of Uncertain Significance CYTO 2019: 34th Congress of the International Society of Advancement of Cytometry Vancouver, British Columbia, Canada
06/22/2019 - 06/26/2019
Flow Cytometric Evaluation of TRBC1 Expression in Tissue Specimens and Body Fluids is a Novel, Sensitive and Specific Method for Assessment of T-Cell Clonality and Diagnosis of T-Cell Neoplasms. 2020 USCAP Annual Meeting Los Angeles, California
02/29/2020 - 03/05/2020
Horatiu Olteanu, MD, PhD
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Poster
Profiling four homocysteine-related enzymes in the NCI60 human cancer cell lines HUPO 3rd Annual World Congress Beijing, China
10/25/2004 - 10/27/2004
Differential utility of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and marrow 2006 USCAP Annual Meeting Atlanta, Georgia
02/11/2006 - 02/17/2006
Immunophenotypic identification of high-risk monoclonal gammopathy of undetermined significance 2007 USCAP Annual Meeting San Diego, California
03/23/2007 - 03/30/2007
Immunophenotype and Laboratory Findings in CD4(+) Large Granular Lymphocyte Leukemia 2008 USCAP Annual Meeting Denver, Colorado
03/01/2008 - 03/07/2008
CD23 expression in plasma cell rnyeloma is specific for abnormalities of chromosome 11, and is associated with primary plasma cell leukemia in this cytogenetic sub-group 2009 USCAP Annual Meeting Boston, Massachusetts
03/07/2009 - 03/13/2009
Expression of natural killer receptors in T lymphocytes and NK cells post stem cell transplantation 2009 USCAP Annual Meeting Boston, Massachusetts
03/07/2009 - 03/13/2009
The specificity of Immunophenotype alterations in blasts in non-acute myeloid disorders 2009 USCAP Annual Meeting Boston, Massachusetts
03/07/2009 - 03/13/2009
Gamma heavy chain disease SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio
09/24/2009 - 09/26/2009
IgM plasma cell myeloma SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio
09/24/2009 - 09/26/2009
Lymphoplasmacytic lymphoma with extensive plasmacytic differentiation and plasmablastic morphology SH/EAHP 2009 workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio
09/24/2009 - 09/26/2009
Plasmacytoid neoplasm with plasmablastic features SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio
09/24/2009 - 09/26/2009
Rapidly progressive fatal dementia secondary to lymphomatosis cerebri CAP Annual Meeting Washington, District of Columbia
10/11/2009 - 10/14/2009
Localized bone marrow aplasia following radiation with discrepant peripheral counts ASCP Annual Meeting Chicago, Illinois
10/28/2009 - 11/01/2009
Horatiu Olteanu, MD, PhD
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High prevalence of Dapsone-induced oxidant hemolysis in North American stem cell transplant recipients without glucose-6-phosphate -dehydrogenases deficiency 2009 ASH Annual Meeting New Orleans, Louisiana
12/05/2009 - 12/08/2009
A Dissection of the CD45/Side Scatter (SS) Blast Gate in Non-acute Myeloid Disorders and Non-neoplastic Bone Marrows 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
CD23(+) Follicular Lymphoma: Immunophenotypic and Clinical Features 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
Immunophenotypic Stability in Plasma Cell Myeloma by Flow Cytometry 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
Immunophenotypic Stability of T-Cell Large Granular Lymphocytic Leukemia and Chronic Lymphoproliferative Disorders of NK Cells by Flow Cytometry 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
Incidental, Immunophenotypically Aberrant Cytotoxic T-Cell Clones in Patients with Other Hematologic Malignancies 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
The Prevalence of Regulatory T-Lymphocytes in Post-Transplant Lymphoproliferative Disorders 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
The Role of Flow Cytometry in the Diagnosis of Intraocular Lymphoma 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
Time and Temperature Stability of T-Cell Subsets 2010 USCAP Annual Meeting Washington, District of Columbia
03/20/2010 - 03/26/2010
Analysis of Variables Affecting the Flow Cytometric Recovery of Plasma Cell Myeloma Cells in Bone Marrow Aspirates 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
CD200 Expression in Plasma Cell Myeloma 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
CD45 Expression in Plasma Cell Myeloma: Comparison of Flow Cytometry and Immunohistochemistry and Relationship to Prognostic Factors 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
Clinic pathologic Analysis of the Impact of CD23 Expression in Plasma Cell Myeloma with t(l 1:14)(q13;q32) 2011 USCAP Annual Meeting, San Antonio, Texas
02/26/2011 - 03/04/2011
Flow Cytometric Analysis of Light Chain Expression Patterns in B-cell Lymphomas Using Monoclonal and Polyclonal Antibodies 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
Horatiu Olteanu, MD, PhD
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Immunophenotypic Stability of Sezary Cells by Flow Cytometry 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
Lymphocyte Subset Reference Ranges for Evaluation of Immune Reconstitution After Allogeneic Stem Cell Transplantation 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
Proliferation Centers in Bone Marrows Involved by Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Clinicopathologic Analysis 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
The Unique Immunophenotype of Double-Hit Lymphomas 2011 USCAP Annual Meeting San Antonio, Texas
02/26/2011 - 03/04/2011
Blast Immunophenotypes by Flow Cytometry in Acute Myeloid Leukemia with Myelodysplasia-Related Changes 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
CD200 Expression in Non-Myeloma Immunoproliferative Disorders 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
Flow Cytometric Blast Immunophenotype in Acute Myeloid Leukemia Arising from Non-Acute Myeloid Disorders 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
Megakaryocytic Hyperplasia Associated with Granulocyte-Colony Stimulating Factor 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
Morphologic Changes in Myelodysplastic Syndrome Treated with Hypomethylating Agents 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
Most Diffuse Large B-Cell Lymphomas Are Identified by Flow Cytometry 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
Persistence of Residual Norma l Peripheral Blood B Cells in Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Identifies a Good Prognostic Subgroup 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
The Prevalence of CD56 Expression by Flow Cytometry in Acute Promyelocytic Leukemia Patients Treated with All-Trans Retinoic Acid and Anthracycline Drug Combinations 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2012 - 03/23/2012
A Retrospective Analysis of the Utility of Pathology Review Criteria for Peripheral Blood and Body Fluids: One Institution's Experience 2012 ASCP Annual Meeting Boston, Massachusetts
10/31/2012 - 11/03/2012
CD200 Expression in Post-Transplant Lymphoproliferative Disorders Correlates With an Increased Frequency of FoxP3(+) Regulatory T-Cells
03/02/2013 - 03/08/2013
Horatiu Olteanu, MD, PhD
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2013 USCAP Annual Meeting Baltimore, Maryland
CD30 Expression in Non-Hodgkin B-cell Lymphoma 2013 USCAP Annual Meeting Baltimore, Maryland
03/02/2013 - 03/08/2013
Dim CD33 Expression in Myelomonocytic Manow Elements: A Novel Description of an Apparently Normal Variant 2013 USCAP Annual Meeting Baltimore, Maryland
03/02/2013 - 03/08/2013
NK Cell Reference Ranges Established by Flow Cytometry in Reactive and Lymphomatous Lymph Nodes 2013 USCAP Annual Meeting Baltimore, Maryland
03/02/2013 - 03/08/2013
The Immunophenotype of Prolymphocytoid Transformation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Revisited 2013 USCAP Annual Meeting Baltimore, Maryland
03/02/2013 - 03/08/2013
Immunophenotypic Analysis of Mycosis Fungoides in Large Cell Transformation 2013 ASCP Annual Meeting Chicago, Illinois
09/18/2013 - 09/21/2013
A Comparison of Therapy-Related and De Novo Chronic Myelomonocytic Leukemia 2014 USCAP Annual Meeting San Diego, California
03/01/2014 - 03/07/2014
Pure Erythroid Leukemia Evolving from Chronic Myeloid Neoplasms: A Report of 3 Cases 2014 USCAP Annual Meeting San Diego, California
03/01/2014 - 03/07/2014
Evaluation of CD43 Expression in Non-Hematologic Malignancies 2014 ASCP Annual Meeting Tampa, Florida
10/08/2014 - 10/10/2014
Reactive Bone Marrow Plasmacytosis : An Update for the Modern Era 2014 ASCP Annual Meeting Tampa, Florida
10/08/2014 - 10/10/2014
Sensitivity and Specificity of Peripheral Blood Findings in Screening for Myelodysplastic Syndrome 2014 ASCP Annual Meeting Tampa, Florida
10/08/2014 - 10/10/2014
Flow Cytometric Analysis of CD23 and FMC-7 Expression in Diffuse Large B-Cell Lymphoma 2014 ICCS Annual Meeting Seattle, Washington
10/10/2014 - 10/14/2014
Bone Marrow Core Biopsy Adequacy and Variability in the United Stated and Canada: A Multicenter Retrospective Study 56th ASH Annual Meeting San Francisco, California
12/06/2014 - 12/09/2014
CD3 Staining on Myeloid Elements in Acute Myeloid Leukemia Bone Marrows 2015 USCAP Annual Meeting Boston, Massachusetts
03/21/2015 - 03/27/2015
CD30 Expression in Post-Transplant Lymphoproliferative Disorders 2015 USCAP Annual Meeting Boston, Massachusetts
03/21/2015 - 03/27/2015
Horatiu Olteanu, MD, PhD
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CD38 Expression in Follicular Lymphoma Correlates with Histologic Grade 2015 USCA P Annual Meeting Boston, Massachusetts
03/21/2015 - 03/27/2015
Evaluation of Proliferation Index in Lymph Nodes with CLL/SLL 2015 USCAP Annual Meeting Boston, Massachusetts
03/21/2015 - 03/27/2015
Novel morphologic finding and clinicopathologic features of acute myeloid leukemias and myelodysplastic syndromes with isolated trisomy 11 2015 USCAP Annual Meeting Boston, Massachusetts
03/21/2015 - 03/27/2015
Unique Aberrant Myeloblast Immunophenotype Associated with Azathioprine Therapy 2015 USCAP Annual Meeting Boston, Massachusetts
03/21/2015 - 03/27/2015
Bone Marrow Monocytosis: A Survey of 150 Cases 2015 ASCP Annual Meeting Long Beach, California
10/28/2015 - 10/30/2015
Immunophenotypic Comparison of Dysplastic and Proliferative Subtypes of Chronic Myelomonocytic Leukemia by Flow Cytometry 2015 ASCP Annual Meeting Long Beach, California
10/28/2015 - 10/30/2015
Donor- Derived Post-Transplant Lymphoproliferative Disorder following Stem Cell Transplantation SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation Long Beach, California
10/29/2015 - 10/31/2015
Monomorphic B-cell PTLD, Burkitt lymphoma SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation Long Beach, California
10/29/2015 - 10/31/2015
Monomorphic T --cell PTLD, Anaplastic large cell lymphoma, ALK (-) SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation Long Beach, California
10/29/2015 - 10/31/2015
Bone Marrow Biopsy Practice and Quality Trends in USA and Canada : A Retrospective Multicenter Study 2016 USCAP Annual Meeting Seattle, Washington
03/12/2016 - 03/18/2016
Correlation of CD79a Expression with Additional B-Cell Markers and Bruton's Tyrosine Kinase Expression in T-Cell Lymphoblastic Leukemia/Lymphoma 2016 USCAP Annual Meeting Seattle, Washington
03/12/2016 - 03/18/2016
PD-L1 Expression Correlates with EBV Status in Post-Transplant Lymphoproliferative Disorders 2016 USCAP Annual Meeting Seattle, Washington
03/12/2016 - 03/18/2016
Tumor Suppressor IRF-1 Expression is Decreased in Post-Transplant Lymphoproliferative Disorders 2016 USCAP Annual Meeting Seattle, Washington
03/12/2016 - 03/18/2016
Variability and Adequacy of Evaluable Marrow Space Length (EMSL) in Bone Marrow Biopsies: A Multi-institutional Study 2016 USCAP Annual Meeting Seattle, Washington
03/12/2016 - 03/18/2016
Horatiu Olteanu, MD, PhD
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Reactivation of Pulmonary Tuberculosis after Use of Ruxolitib for Myelofibrosis AMMI Canada - CACMID Annual Conference Vancouver, British Columbia, Canada
03/30/2016 - 04/02/2016
A patient with a mediastinal mass with features of primary mediastinal B-cell lymphoma and an aggressive clinical course SH/EAHP 2016 Lymphoma Workshop Basel, Switzerland
09/03/2016 - 09/08/2016
Double-Hit" Diffuse Large B-cell Lymphoma With t(2;8), t(l 4;18) And Extensive Necrosis SH/EAHP 2016 Lymphoma Workshop Basel, Switzerland
09/03/2016 - 09/08/2016
Allogeneic Hematopoietic Cell Transplantation (alloHCT) for Extranodal Natural Killer (NK)/T-Cell Lymphoma, Nasal Type (ENKL): A CIBMTR Analysis 2017 EMT Tandem meetings Orlando, Florida
02/22/2017 - 02/26/2017
A Multicenter Study Evaluating the Efficacy of Allogeneic Hematopoietic Cell Transplantation (allo-HCT) in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) 43rd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMI 2017) Marseille, France
03/26/2017 - 03/29/2017
Prevalence and Diagnostic Utility of Dutcher Bodies in Orbital Biopsies 2017 CAP Annual Meeting National Harbor, Maryland
10/08/2017 - 10/11/2017
Comparative Evaluation of Plasmacytoid Dendritic Cell Content in Reactive and Neoplastic Lymphoid Aggregates in Bone Marrow 2018 CAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2018 - 03/23/2018
Computer-based Differential Tally Counter for Bone Marrows 2018 CAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2018 - 03/23/2018
Evaluation of Extranodal Marginal Zone B-cell Lymphoma by Flow Cytometry 2018 CAP Annual Meeting Vancouver, British Columbia, Canada
03/17/2018 - 03/23/2018
Diagnostic Utility of Cerebrospinal Fluid Flow Cytometry in Patients with Hematologic Malignancies 2018 ICCS Annual Meeting Portland, Oregon
09/28/2018 - 10/02/2018
Carcinocythemia: A Rare Entity Becoming More Common? A Case Series and Literature Review 2018 ASCP Annual Meeting Baltimore, Maryland
10/03/2018 - 10/05/2018
Development of a robust, highly sensitive and specific 10-color flow cytometry panel for minimal/measurable residual disease in acute myeloid leukemia. 34th Annual Clinical Cytometry Meeting and Course Atlanta, Georgia
10/06/2019 - 10/08/2019
Flow cytometric assessment of TRBC1 expression in tissue specimens is a novel, sensitive and specific method for evaluation of T-cell clonality and identification of T-cell neoplasms. 34th Annual Clinical Cytometry Meeting and Course Atlanta, Georgia
10/06/2019 - 10/08/2019
Horatiu Olteanu, MD, PhD
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Single-Antibody Detection of T-Cell Receptor Beta Chain Monotypia Resolves Uncertainties in the Identification and Quantitation of Sézary Cells By Routine Flow Cytometry: Towards Accurate and Unequivocal Blood Staging of Cutaneous T-Cell Lymphomas. 61st ASH Annual Meeting Orlando, Florida
12/07/2019 - 12/10/2019
Clinical Utility of T-cell Receptor Constant ß Chain-1 Staining in the Diagnosis of T-cell Large Granular Lymphocytic Leukemia by Flow Cytometry. 2020 USCAP Annual Meeting Los Angeles, California
02/29/2020 - 03/05/2020
Algorithmic Diagnostic Approach and Spectrum of Hematological Malignancies in Patients with Germline Predisposition Syndromes Society of Hematologic Oncology Ninth Annual Meeting (SOHO 2021) Houston, Texas
09/08/2021 - 09/11/2021
BET Inhibitor Pelabresib Decreases Inflammatory Cytokines, Improves Bone Marrow Fibrosis and Function, and demonstrates Clinical Response Irrespective of Mutation Status in Myelofibrosis Patients in the Phase 2 MANIFEST Trial Society of Hematologic Oncology Ninth Annual Meeting (SOHO 2021) Houston, Texas
09/08/2021 - 09/11/2021
Artificial Intelligence-Assisted Classification Tool for Minimal Residual Disease (MRD) Assessment by Flow Cytometry in Patients with Acute Myeloid Leukemia (AML) 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland
10/08/2021 - 10/12/2021
Augmented human intelligence enhances flow cytometric (FC) analysis in the detection of minimal residual disease (MRD) of chronic lymphocytic leukemia (CLL) 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland
10/08/2021 - 10/12/2021
Augmented Human Intelligence Improves Diagnostic Workflow for Myelodysplastic Syndrome (MDS) Flow Cytometry (FC) Data Processing and Analysis 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland
10/08/2021 - 10/12/2021
Cluster-Based Analysis Training for Technologists Improves Accuracy and Understanding of Flow Cytometric Immunophenotyping 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland
10/08/2021 - 10/12/2021
Immunophenotypic Stability of Minimal Residual Disease (MRD) Assessment in B Lymphoblastic Leukemia / Lymphoma (B-ALL) by Flow Cytometry (FC) 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland
10/08/2021 - 10/12/2021
Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) as Demonstrated by Improvements in Bone Marrow Function and Clinical Activity in Patients With Myelofibrosis – Preliminary Data. 63rd ASH Annual Meeting Atlanta, Georgia
12/11/2021 - 12/14/2021
Regional
Invited
Prognostic significance of CD200 expression in immunoproliferative and post transplant lymphoproliferative disorders Hematologic Malignancy and Transplantation Research Program, Medical College of Wisconsin Cancer Center Milwaukee, Wisconsin
02/14/2013
Horatiu Olteanu, MD, PhD
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Clinicopathologic Analysis of the Impact of CD23 Expression in Hematologic Malignancies Hematologic Malignancy and Transplantation Research Program, Medical College of Wisconsin Cancer Center Milwaukee, Wisconsin
10/10/2013
Flow Cytometric Diagnosis of Mature T-Cell Lymphoproliferations 4th Annual Twin Cities Regional Flow Cytometry Conference Minneapolis, Minnesota
03/23/2019
Visiting Professorship Visiting Professorships Diagnostic and prognostic significance of CD200 expression in plasmacytic neoplasms Department of Pathology and Laboratory Medicine Grand Rounds, University of Wisconsin School of Medicine and Public Health Madison, Wisconsin
01/31/2013
Personalized Medicine in Hematologic Malignancies: The Use of Flow Cytometry in Identifying New Diagnostic and Prognostic Markers in Plasma Cell and Lymphoid Disorders Biochemistry Annual Alumni Seminar, University of Nebraska Lincoln, Nebraska
04/23/2013
Clinical and Pathologic Features of Aggressive B-Cell Lymphomas 2015 IOCN Hematology Workshop Cluj-Napoca, Romania
11/05/2015 - 11/07/2015
Biomarker Discovery in Plasmacytoid Neoplasms and Post-Transplant Lymphoproliferative Disorders Department of Pathology, Microbiology and Immunology Laboratory Medicine Grand Rounds, Vanderbilt University School of Medicine Nashville, Tennessee
11/13/2015
Flow Cytometry Diagnosis of Complex Hematopathology Cases Division of Hematopathology, Mayo Clinic Rochester, Minnesota
06/15/2017
Clinical Practice, Interests, and Accomplishments 1. Clinical education and training of residents, fellows, practicing pathologists, and laboratory professionals: A key clinical interest and practice of mine also includes the clinical education and training of future physicians, pathologists, and laboratory professionals. I have made several key contributions that provide guidance and education on how to practice medicine for our future pathologists and laboratorians. These contributions include co-authorship on a comprehensive textbook on Lymph Node Pathology, serving as Program Director for the Hematopathology fellowship, and as member of chair of several clinical practice and education committees of national and international Pathology organizations, including the Association for Clinical Pathology (ASCP), College of American Pathologists (CAP), Society for Hematopathology (SH), and International Clinical Cytometry Society (ICCS). As chair of ASCP’s Pathologist Recertification Individualize Self-Assessment Examination (PRISE) committee, I have overseen and implemented a highly successful clinical education program that over the last 5 years experienced an average of 580 unique participants for each of the 25-30 annual subspecialty modules published by the committee. In addition to practicing pathologists, over 60% of US Pathology residency programs have subscribed to this program, making it a valuable training tool for residents and program directors. 2. Immunophenotypic characterization of hematologic malignancies for relevant diagnostic and prognostic markers: My personal and professional goals have been and will remain a striving for diagnostic excellence in Hematopathology, and a close involvement in, and creation of an environment of enhanced learning for medical professionals, including pathologists and oncologists. Since my initial appointment at the Medical College of Wisconsin, I was grateful for having the opportunity to support the departmental and institutional goals of patient care and education, particularly in providing a diagnostic service which supported the Division of Hematology and Oncology in providing high-quality patient care. Since I took over as medical director, the MCW Clinical Flow Cytometry laboratory experienced a tremendous growth in testing volume, sustaining an average 10% increase/year. Under my supervision, the laboratory transitioned from 4-color to 8-color flow cytometry testing, which is particularly useful in providing more detailed diagnostic information derived from limited specimens and uses less antibodies, thus contributing to a decrease in operating costs. Our laboratory was the first one in the
Horatiu Olteanu, MD, PhD
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state of Wisconsin to offer 8-color flow cytometry testing. We were also following patients treated at a busy bone marrow transplant center, including minimal residual disease analysis for plasma cell myeloma, acute leukemia, and lymphoproliferative disorders, as the first laboratory in the state of Wisconsin to offer these tests. My clinical expertise in flow cytometry and Hematopathology has resulted in several key publications on guiding therapy in patients with T cell lymphoproliferative disorders (Olteanu H, Harrington AM, Hari P, Kroft SH. Imrnunophenotypic Stability of Sezary Cells by Flow Cytometry: Utility of Flow Cytometry in Assessing Response to and Guiding Alemtuzumab Therapy. Am J Clin Pathol. 2012; 137(3):403-411.; Hari P, Raj RV, Olteanu H. Targeting CD38 in Refractory Extranodal Natural Killer Cell-T-Cell Lymphoma. N Engl J Med 2016 Oct 13; 375 (15):1501-1502) and as senior Pathology author for several publications of the Center for International Blood and Bone Marrow Transplant Research (CIBMTR) on the largest North American cohort of patients with aggressive NK cell lymphorpliferative disorders (Hamadani M, Kanate AS, DiGilio A, Ahn KW, Smith SM, Lee JW, Ayala E, Chao N, Hari P, Bolanos-Meade J, Gress R, Smedegaard Anderson N, Chen YB, Farooq U, Schiller G, Yared J, Sureda A, Fenske TS, Olteanu H. Allogeneic Hematopoietic Cell Transplantation for Aggressive NK Cell Leukemia. A Center for International Blood and Marrow Transplant Research Analysis. Biol Blood Marrow Transplant. 2017 May; 23 (5):853-856 Epub 2017 Feb 01; Kanate, A.S., DiGilio, A., Ahn, K.W., Al Malki, M., Jacobsen, E., Steinberg, A., Hamerschlak, N., Kharfan-Dabaja, M., Salit, R., Ball, E., Bashir, Q., Cashen, A., Couriel, D., Diez-Martin, J., Katasanis, E., Linhares, Y., Mori, S., Nash, R., Pawarode, A., Perales, M.A., Phipps, C.D., Richman, C., Savania, B.N., Shapira, M.Y., Stiff, P., Strair, R., Fenske, T.S., Smith, S.M., Sureda, A., Olteanu, H., Hamadani, M.: Allogeneic Hematopoietic Cell Transplantation for Extranodal Natural Killer/T-cell Lymphoma, Nasal Type. A CIBMTR Analysis. Br J Haematol 2017 Aug 2. PMID: 28771676 doi: 10.1111/bjh.14879. [Epub ahead of print]).
Research Interests and Accomplishments 1. Biomarker discovery in hematologic neoplasms: Our group was the first to publish on the clinical and pathologic impact of diagnostic and prognostic markers such as CD23 and CD200 in follicular lymphoma, plasma cell myeloma, and plasma cell dyscrasias. Currently, I am continuing these studies by focusing on post-transplant lymphoproliferative disorders (PTLDs) and the interplay of regulatory T cells (Tregs), CD200 and CD30 expression, and EBV status on clinical outcome. We are employing a combination of tissue microarray immunohistochemistry, in situ hybridization, imaging studies and B-cell receptor gene rearrangement RT-PCR to address the utility of new biomarkers for prognostic and therapeutic purposes. Olteanu, H., Fenske, T.S., Harrington, A.M., Szabo, A., He, P., Kroft, S.H.: CD23 expression in follicular lymphoma: clinicopathologic correlations. Am J Clin Pathol, 135 (1): 46-53, 2011. Buonaccorsi, J.B., Kroft, S.H., Harrington, A.M., VanTuinen, P., Olteanu, H.: Clinicopathologic analysis of the impact of CD23 expression in plasma cell myeloma with t(11;14)(q13;q32). Ann Diagn Pathol, 15 (6): 385-388, 2011. Olteanu, H., Harrington, A.M., Kroft, S.H.: CD200 Expression in Plasma Cells of Non-Myeloma Immunoproliferative Disorders: Clinicopathologic Features and Comparison with Plasma Cell Myeloma. Am J Clin Pathol, 138 (6): 867-876, 2012. Hartley, C., Vaughan, J.W., Jarzembowsi, J., Kroft, S.H, Hosking, P.R., Harrington, A.M., Mackinnon, A.C, Olteanu, H.: CD30 Expression in Monomorphic Post-Transplant Lymphoproliferative Disorder, Diffuse Large B-cell Lymphoma Correlates with Greater Regulatory T-Cell Infiltration. Am J Clin Pathol, 20;148(6):485-493, 2017. 2. Gammaherpesvirus-induced lymphomagenesis in immunocompetent and immune-deficient individuals: I am collaborating with Dr. Vera Tarakanova from the Medical College of Wisconsin on a project which poses a clinically relevant interdisciplinary conundrum at the crossroads of molecularly relevant host factors (IRF-1 expression) and gammaherpervirus-driven lymphomagenesis. Prior to our studies, the role of IRF-1 in the regulation of gammaherpesvirus replication, chronic infection, and pathogenesis was poorly understood. Our group was the first to demonstrate that gammaherpesvirus infection synergizes with IRF-1 deficiency to induce B cell lymphomas. This innovative project is based on our observation that IRF-1 suppresses gammaherpesvirus-driven expansion of germinal center B cells; this is the first time IRF-1 has been implicated in virus-driven B cell differentiation and has resulted in intramural and extramural funding. Successful completion of the proposed studies will establish a novel and tractable animal model of gammaherpesvirus lymphomagenesis. The ultimate, long-term goal of our research is to determine the extent to which IRF-1-regulated gene expression suppresses gammaherpesvirus-induced cancer in humans. Mboko, J.P., Olteanu, H., Ray, A., Darrah, E., Kulinski, J.M., Cui, W., Dittel, B., Gauld, S.B., Tarakanova, V.L.: Tumor suppressor IRF-1 counteracts expansion of germinal centers driven by a cancer-associated gammaherpesvirus. J Virol, 90 (6): 2818-2829, 2015. Darrah, E., Johnson, K.E., Lange, P.T., Olteanu, H., Tarakanova, V.L.: Conserved viral protein kinase selectively promotes irrelevant B cell responses. J Exp Med 2018 (submitted for review) 3. Immunophenotypic characterization of hematologic malignancies for relevant diagnostic and prognostic markers: Our group’s clinical research is focused on the application of specialized ancillary techniques, in particular flow cytometry, to the clinical and pathologic characterization of hematolymphoid malignancies. We were the first to publish on the temporal immunophenotypic changes of neoplastic cells in plasma cell myeloma and T-cell large granular lymphocytic leukemia, and to provide a detailed characterization of normal and aberrant NK cells in the post-transplant setting or in neoplastic conditions: Spears, M.D., Harrington, A.M., Kroft, S.H., Olteanu, H.: Immunophenotypic stability of T-cell large granular lymphocytic leukemia by flow cytometry. Br J Haematol, 151
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(1): 97-99, 2010. Olteanu, H., Schur, B.C., Atallah, E., Bredeson, C., Kroft, S.H.: Expression of Natural Killer Receptors in T and NK cells: Comparison of Healthy Individuals, Stem Cell Transplant Patients and Chemotherapy Patients. Leuk Lymphoma 51 (3): 481-487, 2010. Morice, W.G., Jevremovic, D., Olteanu, H., Roden, A., Nowakowski, G., Kroft, S.H., Hanson, C.A., Kurtin, P.J.: Chronic Lymphoproliferative Disorder of Natural Killer Cells: A Distinct Entity with Sub-Types Correlating With Normal Natural Killer Cell Subsets. Leukemia 24 (4): 881-884, 2010. Hari, P., Raj, R., Olteanu, H.: Targeting CD38 in Refractory Natural Killer Cell-T-Cell Lymphoma. New Engl J Med, 375 (15): 1501-1502, 2016.
Research Grants Awarded
Active Grants
Federal Co-Investigator lRF-1: A Brake to Limit Gammaherpesvirus Infection and Pathogenesis .
Funded by NIH. (RO1 CA 203923) 09/2016 - 08/2021
Federal sub award Program Director / Principal Investigator
IRF-1: a brake to limit gammaherpesvirus infection and pathogenesis. Funded by National Cancer Institute. (CA 203923)
12/2017 - 11/2021
Program Director / Principal Investigator
ECOG-ACRIN Operations Center – Clinical Trials - EAA171 BIQSFP Supplement. Funded by National Cancer Institute. (CA 180820)
03/2020 - 02/2022
Completed Grants
Foundation Co-Investigator Role of Tumor Suppressor IRF-1 in Viral Lymphomagenesis. Funded by
Thomas A. and Lorraine M. Rosenberg Award for Translational Cancer Research
05/2016 - 04/2018
Horatiu Olteanu, MD, PhD
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Bibliography
Peer-reviewed Articles 1. Olteanu H, Banerjee R. Human methionine synthase reductase, a soluble P450 reductase-like dual
flavoprotein, is sufficient for NADPH-dependent methionine synthase activation J Biol Chem. 2001; 276(38):35558-35563. PMID: 11466310 DOI: 10.1074/jbc.M103707200
2. Olteanu H, Munson T, Banerjee R. Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase. Biochemistry. 2002 Nov 12; 41 (45):13378-85 PMID: 12416982
3. Olteanu H, Banerjee R. Redundancy in the pathway for redox regulation of mammalian methionine synthase: reductive activation by the dual flavoprotein, novel reductase 1. J Biol Chem. 2003 Oct 3; 278 (40):38310-4 Epub 2003 July 18 PMID: 12871938 DOI: 10.1074/jbc.M306282200
4. Olteanu H, Wolthers KR, Munro AW, Scrutton NS, Banerjee R. Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase. Biochemistry. 2004 Feb 24; 43 (7):1988-97 PMID: 14967039 DOI: 10.1021/bi035910i
5. Waly M, Olteanu H, Banerjee R, Choi SW, Mason JB, Parker BS, Sukumar S, Shim S, Sharma A, Benzecry JM, Power-Charnitsky VA, Deth RC. Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Mol Psychiatry. 2004 Apr; 9 (4):358-70 PMID: 14745455 DOI: 10.1038/sj.mp.4001476
6. Leal NA, Olteanu H, Banerjee R, Bobik TA. Human ATP:Cob(I)alamin adenosyltransferase and its interaction with methionine synthase reductase. J Biol Chem. 2004 Nov 12; 279 (46):47536-42 Epub 2004 Aug 30 PMID: 15347655 DOI: 10.1074/jbc.M405449200
7. Olteanu H, Gerber D, Partridge K, Sarode R. Acute hemolytic transfusion reaction secondary to anti-Fy3. Immunohematology. 2005; 21 (2):48-52 PMID: 15981343
8. Zhang W, Braun A, Bauman Z, Olteanu H, Madzelan P, Banerjee R. Expression profiling of homocysteine junction enzymes in the NCI60 panel of human cancer cell lines. Cancer Res. 2005 Feb 15; 65 (4):1554-60 PMID: 15735045 DOI: 10.1158/0008-5472.CAN-04-1554
9. Olteanu H, Xu Y. The use of flow cytometry in diagnosis of paroxysmal nocturnal hemoglobinuria. Lab Med. 2006; 37(8):2-6.
10. Olteanu H, Karandikar NJ, McKenna RW, Xu Y. Differential usefulness of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and bone marrow. Am J Clin Pathol. 2006 Nov; 126 (5):781-8 PMID: 17050075 DOI: 10.1309/AT9Y-6WR0-3PX1-K228
11. Dyszkiewicz-Korpanty A, Olteanu H, Frenkel EP, Sarode R. Clopidogrel anti-platelet effect: an evaluation by optical aggregometry, impedance aggregometry, and the platelet function analyzer (PFA-100). Platelets. 2007 Nov; 18 (7):491-6 PMID: 17852774 DOI: 10.1080/09537100701280654
12. Olteanu H, Wang HY, Chen W, McKenna RW, Karandikar NJ. Immunophenotypic studies of monoclonal gammopathy of undetermined significance. BMC Clin Pathol. 2008 Nov 28; 8:13 PMID: 19040735 PMCID: 2606678 DOI: 10.1186/1472-6890-8-13
13. Olteanu H, Downes KA, Patel J, Praprotnik D, Sarode R. Warfarin does not interfere with lupus anticoagulant detection by dilute Russell's viper venom time. Clin Lab. 2009; 55 (3-4):138-42 PMID: 19462936
14. Olteanu H, Harrington A, Kroft SH. Sperm in peritoneal fluid from a man with ascites: a case report. Cases J. 2009 Nov 12; 2:192 PMID: 19946502 PMCID: 2783147 DOI: 10.1186/1757-1626-2-192
15. Parker SM, Olteanu H, VanTuinen P, Lawton CA, Schultz CJ, Christians KK, Fenske TS. Follicular lymphoma transformation to dual translocated Burkitt-like lymphoma: improved disease control associated with radiation therapy. Int J Hematol. 2009 Dec; 90 (5):616-622 Epub 2009 Nov 25 PMID: 19937165 DOI: 10.1007/s12185-009-0444-9
16. Olteanu H, Karandikar NJ, Eshoa C, Kroft SH. Laboratory Findings in CD4(+) Large Granular Lymphocytoses. Int J Lab Hematol. 2010; 32(1 Pt 1):e9-e16. PMID: 20089001
17. Olteanu H, Schur BC, Bredeson C, Atallah E, Kroft SH. Expression of natural killer receptors in T- and NK-cells: comparison of healthy individuals, patients with prior stem cell transplant, and patients undergoing chemotherapy. Leuk Lymphoma. 2010 Mar; 51 (3):481-7 Epub 2010 Feb 08 PMID: 20141431 DOI: 10.3109/10428190903552120
18. Harrington AM, Currey A, Olteanu H, Kroft SH. Persistent localized bone marrow aplasia after radiotherapy with preserved peripheral counts: a study of 8 cases. Ann Diagn Pathol. 2010 Jun; 14 (3):168-72 PMID: 20471561 DOI: 10.1016/j.anndiagpath.2010.02.006
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19. * Plaza JA, Ortega P, Lynott J, Mullane M, Kroft S, Olteanu H. CD8-positive primary cutaneous anaplastic large T-cell lymphoma (PCALCL): case report and review of this unusual variant of PCALCL. Am J Dermatopathol. 2010 Jul; 32 (5):489-91 PMID: 20442639 DOI: 10.1097/DAD.0b013e3181c57ec2
20. Harrington A, Olteanu H, Kroft S. The specificity of immunophenotypic alterations in blasts in nonacute myeloid disorders. Am J Clin Pathol. 2010 Nov; 134 (5):749-61 PMID: 20959658 DOI: 10.1309/AJCPFNF5MN1GDWKU
21. Olteanu H, Harrington AM, Hari P, Kroft SH. CD200 expression in plasma cell myeloma Br J Haematol. 2011; 153(3):408-411. PMID: 21275968
22. Olteanu H, Fenske TS, Harrington AM, Szabo A, He P, Kroft SH. CD23 expression in follicular lymphoma: clinicopathologic correlations. Am J Clin Pathol. 2011 Jan; 135 (1):46-53 PMID: 21173123 DOI: 10.1309/AJCP27YWLIQRAJPW
23. Torgerson S, Olteanu H, Tinguely M, Fenske TS. Central nervous system Hodgkin lymphoma: case report and review of the literature. J Neurooncol. 2011 Apr; 102 (2):329-34 Epub 2010 July 31 PMID: 20676729 DOI: 10.1007/s11060-010-0320-8
24. Olteanu H. Case Study Interpretation--Houston: Case 2. Classical Hodgkin lymphoma. Cytometry B Clin Cytom. 2011 Jul-Aug; 80 (4):258-60 Epub 2011 June 02 PMID: 21638769 DOI: 10.1002/cyto.b.20598
25. Spears MD, Olteanu H, Kroft SH, Harrington AM. The immunophenotypic stability of plasma cell myeloma by flow cytometry. Int J Lab Hematol. 2011 Oct; 33 (5):483-91 Epub 2011 Apr 07 PMID: 21470371 DOI: 10.1111/j.1751-553X.2011.01317.x
26. * Buonaccorsi JN, Kroft SH, Harrington AM, VanTuinen P, Olteanu H. Clinicopathologic analysis of the impact of CD23 expression in plasma cell myeloma with t(11;14)(q13;q32). Ann Diagn Pathol. 2011 Dec; 15 (6):385-8 Epub 2011 July 02 PMID: 21724429 DOI: 10.1016/j.anndiagpath.2011.04.004
27. * Horna P, Olteanu H, Kroft SH, Harrington AM. Flow cytometric analysis of surface light chain expression patterns in B-cell lymphomas using monoclonal and polyclonal antibodies. Am J Clin Pathol. 2011 Dec; 136 (6):954-9 PMID: 22095382 DOI: 10.1309/AJCP3C2QZZBPTMLB
28. Olteanu H, Schur BC, Harrington AM, Kroft SH. Time and temperature stability of T-cell subsets evaluated by a dual-platform method. Am J Blood Res. 2012; 2 (2):128-35 Epub 2012 May 25 PMID: 22762032 PMCID: 3384401
29. Olteanu H, Harrington AM, George B, Hari PN, Bredeson C, Kroft SH. High prevalence of Dapsone-induced oxidant hemolysis in North American SCT recipients without glucose-6-phosphate-dehydrogenase deficiency. Bone Marrow Transplant. 2012 Mar; 47 (3):399-403 Epub 2011 Apr 11 PMID: 21478917 DOI: 10.1038/bmt.2011.83
30. * Vaughan J, Harrington AM, Hari PN, Kroft SH, Olteanu H. Immunophenotypic stability of Sezary cells by flow cytometry: usefulness of flow cytometry in assessing response to and guiding alemtuzumab therapy. Am J Clin Pathol. 2012 Mar; 137 (3):403-11 PMID: 22338052 DOI: 10.1309/AJCP7QHH5XASTJPL
31. Harrington AM, Olteanu H, Kroft SH. A dissection of the CD45/side scatter "blast gate". Am J Clin Pathol. 2012 May; 137 (5):800-4 PMID: 22523220 DOI: 10.1309/AJCPN4G1IZPABRLH
32. Olteanu H, Harrington AM, Kroft SH. CD200 expression in plasma cells of nonmyeloma immunoproliferative disorders: clinicopathologic features and comparison with plasma cell myeloma. Am J Clin Pathol. 2012 Dec; 138 (6):867-76 PMID: 23161721 DOI: 10.1309/AJCP3TQR1TFHHGAS
33. Cogbill CH, Spears MD, Vantuinen P, Harrington AM, Olteanu H, Kroft SH. Morphologic and cytogenetic variables affect the flow cytometric recovery of plasma cell myeloma cells in bone marrow aspirates. Int J Lab Hematol. 2015 Dec; 37 (6):797-808 Epub 2015 July 30 PMID: 26224420 DOI: 10.1111/ijlh.12411
34. Mboko WP, Olteanu H, Ray A, Xin G, Darrah EJ, Kumar SN, Kulinski JM, Cui W, Dittel BN, Gauld SB, Tarakanova VL. Tumor Suppressor Interferon-Regulatory Factor 1 Counteracts the Germinal Center Reaction Driven by a Cancer-Associated Gammaherpesvirus. J Virol. 2015 Dec 30; 90 (6):2818-29 PMID: 26719266 PMCID: 4810652 DOI: 10.1128/JVI.02774-15
35. Abidi MZ, Haque J, Varma P, Olteanu H, Guru Murthy GS, Dhakal B, Hari P. Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib. Case Rep Hematol. 2016; 2016:2389038 Epub 2016 Oct 23 PMID: 27843657 PMCID: 5097796 DOI: 10.1155/2016/2389038
36. Olteanu H. Role of Flow Cytometry in the Diagnosis and Prognosis of Plasma Cell Myeloma. Surg Pathol Clin. 2016 Mar; 9 (1):101-16 PMID: 26940271 DOI: 10.1016/j.path.2015.09.009
37. * Li H, Hasserjian RP, Kroft SH, Harrington AM, Wheaton SE, Pildain A, Ewalt MD, Gratzinger D, Hosking P, Olteanu H. Pure Erythroid Leukemia and Erythroblastic Sarcoma Evolving From Chronic Myeloid Neoplasms. Am J Clin Pathol. 2016 Apr; 145 (4):538-51 Epub 2016 Apr 22 PMID: 27124944 DOI: 10.1093/ajcp/aqw033
38. Harrington AM, Schelling LA, Ordobazari A, Olteanu H, Hosking PR, Kroft SH. Immunophenotypes of Chronic Myelomonocytic Leukemia (CMML) Subtypes by Flow Cytometry: A Comparison of CMML-1 vs CMML-2,
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Myeloproliferative vs Dysplastic, De Novo vs Therapy-Related, and CMML-Specific Cytogenetic Risk Subtypes. Am J Clin Pathol. 2016 Aug; 146 (2):170-81 Epub 2016 July 13 PMID: 27413139 DOI: 10.1093/ajcp/aqw084
39. Chang JC, Harrington AM, Olteanu H, VanTuinen P, Kroft SH. Proliferation centers in bone marrows involved by chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic analysis. Ann Diagn Pathol. 2016 Dec; 25:15-19 Epub 2016 Aug 18 PMID: 27806839 DOI: 10.1016/j.anndiagpath.2016.07.011
40. * Epperla N, Olteanu H, Hamadani M. Think outside the box: Acanthamoeba encephalitis following autologous haematopoietic stem cell transplantation. Br J Haematol. 2016 Dec; 175 (5):758 Epub 2016 Sept 21 PMID: 27650173 DOI: 10.1111/bjh.14329
41. * Popa G, Blag C, Olteanu H. Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient. Pediatr Dev Pathol. 2017 Jan-Feb; 20 (1):58-62 PMID: 28276292 DOI: 10.1177/1093526616671047
42. * Rowan DJ, Logunova V, van Tuinen P, Olteanu H, Peterson JF. Circulating Breast Carcinoma Cells Mimicking Therapy-Related Acute Myeloid Leukemia. Int J Surg Pathol. 2017 Feb; 25 (1):87-93 Epub 2016 Aug 20 PMID: 27543510 DOI: 10.1177/1066896916664986
43. Hamadani M, Kanate AS, DiGilio A, Ahn KW, Smith SM, Lee JW, Ayala E, Chao N, Hari P, Bolanos-Meade J, Gress R, Smedegaard Anderson N, Chen YB, Farooq U, Schiller G, Yared J, Sureda A, Fenske TS, Olteanu H. Allogeneic Hematopoietic Cell Transplantation for Aggressive NK Cell Leukemia. A Center for International Blood and Marrow Transplant Research Analysis. Biol Blood Marrow Transplant. 2017 May; 23 (5):853-856 Epub 2017 Feb 01 PMID: 28161608 PMCID: 5410937 DOI: 10.1016/j.bbmt.2017.01.082
44. * Batdorf BH, Kroft SH, Hosking PR, Harrington AM, Mackinnon AC, Olteanu H. Evaluation of CD43 expression in non-hematopoietic malignancies. Ann Diagn Pathol. 2017 Aug; 29:23-27 Epub 2017 Apr 26 PMID: 28807337 DOI: 10.1016/j.anndiagpath.2017.04.010
45. * Hartley C, Vaughan JW, Jarzembowski J, Kroft SH, Hosking P, Harrington AM, Olteanu H. CD30 Expression in Monomorphic Posttransplant Lymphoproliferative Disorder, Diffuse Large B-Cell Lymphoma Correlates With Greater Regulatory T-Cell Infiltration. Am J Clin Pathol. 2017 Nov 20; 148 (6):485-493 PMID: 29126177 DOI: 10.1093/ajcp/aqx097
46. Kharfan-Dabaja MA, Al Malki MM, Deotare U, Raj RV, El-Jurdi N, Majhail N, Cherry MA, Bashir Q, Darrah J, Nishihori T, Sibai H, Hamadani M, de Lima M, Gerds AT, Selby G, Qazilbash MH, Forman SJ, Ayala E, Lipton JH, Hari PN, Muzzafar T, Zhang L, Olteanu H, Perkins J, Sokol L, Kumar A, Ahmed S. Haematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a North American multicentre collaborative study. Br J Haematol. 2017 Dec; 179 (5):781-789 Epub 2017 Oct 04 PMID: 28980314 DOI: 10.1111/bjh.14954
47. Sinkoff J, Olteanu H, Peterson JF, Shah NN. Leukemic phase and CSF involvement of diffuse large B-cell lymphoma with a complex karyotype including a TP53 deletion. Clin Case Rep. 2018 Jan; 6 (1):235-237 Epub 2017 Dec 05 PMID: 29375876 PMCID: 5771872 DOI: 10.1002/ccr3.1250
48. Kharfan-Dabaja MA, Raj R, Nikolaenko L, Ahmed S, Reddy N, Nathan S, Cherry M, El-Jurdi N, Obiozor C, Fenske TS, Song J, Muzzafar T, Ayala E, Savani B, Khawandanah M, Caimi PF, Hamadani M, Forman SJ, Hussaini M, de Lima M, Olteanu H, Shah B, Chavez JC, Al Malki M, Kumar A, Ganguly S. Efficacy of High-Dose Therapy and Autologous Hematopoietic Cell Transplantation in Gray Zone Lymphoma: A US Multicenter Collaborative Study. Biol Blood Marrow Transplant. 2018 Mar; 24 (3):486-493 Epub 2017 Dec 07 PMID: 29225164 DOI: 10.1016/j.bbmt.2017.11.033
49. * Abdelkader A, Olteanu H. Clinical and Pathologic Features of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Pediatric Patient Arch Clin Cases. 2018; 5(2):47-52. DOI: http://dx.doi.org/10.22551/2018.19.0502.10127
50. Merzianu M, Groman A, Hutson A, Cotta C, Brynes RK, Orazi A, Reddy V, Teruya-Feldstein J, Amre R, Balasubramanian M, Brandao G, Cherian S, Courville E, Czuchlewski D, Fan G, Grier D, Hoehn D, Inamdar KV, Juskevicius R, Kaur P, Lazarchick J, Lewis MR, Miles RR, Myers JB, Nasr MR, Qureishi HN, Olteanu H, Robu VG, Salaru G, Vajpayee N, Vos J, Zhang L, Zhang S, Aye L, Brega E, Coad JE, Grantham J, Ivelja S, McKenna R, Sultan K, Wilding G, Hutchison R, Peterson L, Cheney RT. Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada: A Multicenter Study. Am J Clin Pathol. 2018 Oct 1; 150 (5):393-405 PMID: 30052721 PMCID: 6166687 DOI: 10.1093/ajcp/aqy066
51. Ronen S, Kroft SH, Olteanu H, Hosking PR, Harrington AM. Carcinocythemia: A rare entity becoming more common? A 3-year, single institution series of seven cases and literature review. Int J Lab Hematol. 2019 Feb; 41 (1):69-79 Epub 2018 Sept 14 PMID: 30216684 DOI: 10.1111/ijlh.12924
52. Shah NN, Szabo A, Saba R, Strelec L, Kodali D, Vaughn JL, Esan O, Yang DT, Mato AR, Kanate AS, Olteanu H, Hamadani M, Fenske TS, Kenkre VP, Svoboda J, Cashen AF, Epperla N. Multicenter Analysis of
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Advanced Stage Grade 3A Follicular Lymphoma Outcomes by Frontline Treatment Regimen. Clin Lymphoma Myeloma Leuk. 2019 Feb; 19 (2):95-102 Epub 2018 Nov 12 PMID: 30581160 DOI: 10.1016/j.clml.2018.11.010
53. Jevremovic D, Olteanu H. Flow Cytometry Applications in the Diagnosis of T/NK-Cell Lymphoproliferative Disorders. Cytometry B Clin Cytom. 2019 Mar; 96 (2):99-115 Epub 2019 Feb 06 PMID: 30729667 DOI: 10.1002/cyto.b.21768
54. Darrah EJ, Jondle CN, Johnson KE, Xin G, Lange PT, Cui W, Olteanu H, Tarakanova VL. Conserved Gammaherpesvirus Protein Kinase Selectively Promotes Irrelevant B Cell Responses. J Virol. 2019 Apr 15; 93 (8) Epub 2019 Apr 03 PMID: 30728267 PMCID: 6450124 DOI: 10.1128/JVI.01760-18
55. Shi M, Jevremovic D, Otteson GE, Timm MM, Olteanu H, Horna P. Single Antibody Detection of T-Cell Receptor alphabeta Clonality by Flow Cytometry Rapidly Identifies Mature T-Cell Neoplasms and Monotypic Small CD8-Positive Subsets of Uncertain Significance. Cytometry B Clin Cytom. 2020 Jan; 98 (1):99-107 Epub 2019 Apr 11 PMID: 30972977 DOI: 10.1002/cyto.b.21782
56. Shi M, Rech KL, Otteson GE, Horna P, Olteanu H, Pardanani A, Chen D, Jevremovic D. Prevalence and spectrum of T-cell lymphoproliferative disorders in patients with Hypereosinophilia: A reference laboratory experience. Ann Diagn Pathol. 2020 Feb; 44:151412 Epub 2019 Oct 18 PMID: 31778950 DOI: 10.1016/j.anndiagpath.2019.151412
57. Polonis K, Schultz MJ, Olteanu H, Smadbeck JB, Johnson SH, Vasmatzis G, Xu X, Greipp PT, Ketterling RP, Hoppman NL, Baughn LB, Peterson JF. Detection of cryptic CCND1 rearrangements in mantle cell lymphoma by next generation sequencing. Ann Diagn Pathol. 2020 Jun; 46:151533 Epub 2020 May 06 PMID: 32408254 DOI: 10.1016/j.anndiagpath.2020.151533
58. * Vaughan JW, Shi M, Horna P, Olteanu H. Increased CD200 expression in post-transplant lymphoproliferative disorders correlates with an increased frequency of FoxP3(+) regulatory T cells. Ann Diagn Pathol. 2020 Oct; 48:151585 Epub 2020 Aug 14 PMID: 32829067 DOI: 10.1016/j.anndiagpath.2020.151585
59. Shi M, Olteanu H, Jevremovic D, He R, Viswanatha D, Corley H, Horna P. T-cell clones of uncertain significance are highly prevalent and show close resemblance to T-cell large granular lymphocytic leukemia. Implications for laboratory diagnostics. Mod Pathol. 2020 Oct; 33 (10):2046-2057 Epub 2020 May 13 PMID: 32404954 DOI: 10.1038/s41379-020-0568-2
60. Shi M, Nguyen P, Timm MM, Otteson GE, Horna P, Olteanu H, Jevremovic D. Cytoplasmic Expression of CD3epsilon Heterodimers by Flow Cytometry Rapidly Distinguishes Between Mature T-Cell and Natural Killer-Cell Neoplasms. Am J Clin Pathol. 2020 Oct 13; 154 (5):683-691 PMID: 32589191 DOI: 10.1093/ajcp/aqaa086
61. Sheets JW, Eulitt P, He R, Olteanu H, Coombs CC, Foster MC, Montgomery ND, Zeidner JF. Philadelphia Chromosome-positive Acute Myeloid Leukemia With e1a3 BCR-ABL1 Fusion Transcript. Hemasphere. 2020 Dec; 4 (6):e484 Epub 2020 Oct 14 PMID: 33134868 PMCID: 7566865 DOI: 10.1097/HS9.0000000000000484
62. Horna P, Shi M, Olteanu H, Johansson U. Emerging Role of T-cell Receptor Constant beta Chain-1 (TRBC1) Expression in the Flow Cytometric Diagnosis of T-cell Malignancies. Int J Mol Sci. 2021 Feb 12; 22 (4) PMID: 33673033 PMCID: 7918842 DOI: 10.3390/ijms22041817
63. Horna P, Shi M, Jevremovic D, Craig FE, Comfere NI, Olteanu H. Utility of TRBC1 Expression in the Diagnosis of Peripheral Blood Involvement by Cutaneous T-Cell Lymphoma. J Invest Dermatol. 2021 Apr; 141 (4):821-829.e2 Epub 2020 Oct 10 PMID: 33049270 DOI: 10.1016/j.jid.2020.09.011
64. Li M, Binder M, Lasho T, Ferrer A, Gangat N, Al-Kali A, Mangaonkar A, Elliott M, Litzow M, Hogan W, Pardanani A, Wolanskyj-Spinner A, Howard M, King RL, Shah M, Alkhateeb H, Begna K, Tefferi A, Finke C, Oliveira J, Ketterling R, Olteanu H, Patnaik MM. Clinical, molecular, and prognostic comparisons between CCUS and lower-risk MDS: a study of 187 molecularly annotated patients. Blood Adv. 2021 Apr 27; 5 (8):2272-2278 PMID: 33904893 PMCID: 8095155 DOI: 10.1182/bloodadvances.2020003976
65. Berg H, Otteson GE, Corley H, Shi M, Horna P, Jevremovic D, Olteanu H. Flow cytometric evaluation of TRBC1 expression in tissue specimens and body fluids is a novel and specific method for assessment of T-cell clonality and diagnosis of T-cell neoplasms. Cytometry B Clin Cytom. 2021 May; 100 (3):361-369 Epub 2020 Apr 25 PMID: 32333725 DOI: 10.1002/cyto.b.21881
66. Zheng G, He R, Reichard KK, Peterson JF, Olteanu H, Oliveira JL, Rangan A, Chen D, Shi M. Genetic and Clinical Studies of Patients With Increased Multinucleated Megakaryocytes in Bone Marrow as an Isolated Finding: A Diagnostic Pitfall for Myelodysplastic Syndrome. Am J Surg Pathol. 2021 May 13 [Epub ahead of print] PMID: 33999554 DOI: 10.1097/PAS.0000000000001732
67. Horna P, Olteanu H, Jevremovic D, Otteson GE, Corley H, Ding W, Parikh SA, Shah MV, Morice WG, Shi M. Single-Antibody Evaluation of T-Cell Receptor beta Constant Chain Monotypia by Flow Cytometry Facilitates the Diagnosis of T-Cell Large Granular Lymphocytic Leukemia. Am J Clin Pathol. 2021 Jun 17; 156 (1):139-148 PMID: 33438036 DOI: 10.1093/ajcp/aqaa214
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68. Horna P, Otteson GE, Shi M, Jevremovic D, Yuan J, Olteanu H. Flow Cytometric Evaluation of Surface and Cytoplasmic TRBC1 Expression in the Differential Diagnosis of Immature T-Cell Proliferations. Am J Clin Pathol. 2021 Jul 24 Epub 2021 July 24 PMID: 34302330 DOI: 10.1093/ajcp/aqab098
69. Rozenova KA, Jevremovic D, Reichard KK, Nguyen P, Otteson GE, Timm MM, Horna P, Olteanu H, Shi M. CD2 and CD7 are sensitive flow cytometry screening markers for T-lineage acute leukemia(s): a study of 465 acute leukemia cases. Hum Pathol. 2021 Aug; 114:66-73 Epub 2021 May 18 PMID: 34019867 DOI: 10.1016/j.humpath.2021.05.007
70. Guenzel AJ, Smadbeck JB, Golden CL, Williamson CM, Benevides Demasi JC, Vasmatzis G, Pearce KE, Olteanu H, Xu X, Hoppman NL, Greipp PT, Baughn LB, Ketterling RP, Peterson JF. Clinical utility of next generation sequencing to detect IGH/IL3 rearrangements [t(5;14)(q31.1;q32.1)] in B-lymphoblastic leukemia/lymphoma. Ann Diagn Pathol. 2021 Aug; 53:151761 Epub 2021 May 10 PMID: 33991782 DOI: 10.1016/j.anndiagpath.2021.151761
71. Martin ES, Ferrer A, Mangaonkar AA, Khan SP, Kohorst MA, Joshi AY, Hogan WJ, Olteanu H, Moyer AM, Al-Kali A, Tefferi A, Chen D, Wudhikarn K, Go R, Viswanatha D, He R, Ketterling R, Nguyen PL, Oliveira JL, Gangat N, Lasho T, Patnaik MM. Spectrum of hematological malignancies, clonal evolution and outcomes in 144 Mayo Clinic patients with germline predisposition syndromes. Am J Hematol. 2021 Aug 14 [Epub ahead of print] PMID: 34390506 DOI: 10.1002/ajh.26321
Non-Peer-reviewed Articles 1. Olteanu H, Gander RM, Southern PM. West Nile Virus Serology Testing The Southwestern Lab Bulletin. 2005;
10(9):1-2.
Books 1. Olteanu H, Harrington AM, Kroft SH. Lymph Nodes - Demos Surgical Pathology Guides New York, NY:
Demos Medical Publishing; 2013.245p.
Book Chapters 1. Olteanu H, Banerjee R. Cobalamin-dependent remethylation. In: Homocysteine in Health and Disease.
Cambridge University Press; 2001. p. 135-144. 2. Olteanu H, Banerjee R. Biochemical studies of human methionine synthase reductase. In: Chemistry and
Biochemistry of Pteridines and Folates. Kluwer Academic Publishers; 2002. p. 537-542. 3. Olteanu H. Histiocytic and Dendritic Cell Neoplasms. In: Lymph Nodes - Demos Surgical Pathology Guides.
New York, NY: Demos Medical Publishing; 2013. p. 201-12. 4. Olteanu H. Lymph Node Inclusions. In: Lymph Nodes - Demos Surgical Pathology Guides. New York, NY:
Demos Medical Publishing; 2013. p. 71-6. 5. Olteanu H. Lymphadenopathies Associated With Systemic Disorders. In: Lymph Nodes - Demos Surgical
Pathology Guides. New York, NY: Demos Medical Publishing; 2013. p. 45-70. 6. Olteanu H. Mature B-cell Neoplasms. In: Lymph Nodes - Demos Surgical Pathology Guides. New York, NY:
Demos Medical Publishing; 2013. p. 99-142. 7. Olteanu H. Reactive Lymphadenopathies. In: Olteanu, H, Harrington AM, Kroft SH, editor(s). Lymph Nodes -
Demos Surgical Pathology Guides. 2013. p. 33-44. 8. Olteanu H. Spindle Cell Neoplasms of Lymph Nodes. In: Lymph Nodes - Demos Surgical Pathology Guides.
New York, NY: Demos Medical Publishing; 2013. p. 77-82. 9. Olteanu H. Vascular Lymphadenopathies and Neoplsms of Lymph Nodes. In: Lymph Nodes - Demos Surgical
Pathology Guides. New York, NY: Demos Medical Publishing; 2013. p. 83-92. 10. Olteanu H, Allen TC, Suster S. B-cell lymphoma, Mediastinal, Diffuse and Large. In: Pathology of the Pleura
and Mediastinum (Encyclopedia of Pathology). 2018. p. 33-39. 11. Olteanu H, Allen TC, Suster S. Castleman disease, Mediastinal. In: Pathology of the Pleura and Mediastinum
(Encyclopedia of Pathology). 2018. p. 47-55. 12. Olteanu H, Allen TC, Suster S. Hodgkin lymphoma, Mediastinal. In: Pathology of the Pleura and Mediastinum
(Encyclopedia of Pathology). 2018. p. 160-169. 13. Olteanu H, Molina T, Fend F. Lymphoblastic Lymphoma/Leukemia, Mediastinal. In: Hematopathology
(Encyclopedia of Pathology). 2018. 14. Olteanu H, Allen TC, Suster S. Mediastinal Anaplastic Large Cell Lymphoma. In: Pathology of the Pleura and
Mediastinum (Encyclopedia of Pathology). 2018. p. 200-210.
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15. Olteanu H, Allen TC, Suster S. Mediastinal Mucosa-Associated Lymphoid Tissue Lymphoma. In: Pathology of the Pleura and Mediastinum (Encyclopedia of Pathology). 2018. p. 256-261.
16. Olteanu H, Allen TC, Suster S. Pleomorphic Lymphoma, Mediastinal. In: Pathology of the Pleura and Mediastinum (Encyclopedia of Pathology). 2018. p. 303-307.
17. Olteanu, H.. Lymphoblastic Leukemia/Lymphoma. In: Molina, T.J., editor(s). Hematopathology (Encyclopedia of Pathology). Springer, Cham; 2019.
Audio/Video/CD-ROM/etc. 1. Olteanu H. Flow Cytometric Evaluation of Natural Killer Cell-Associated Receptors (NKRs) International
Clinical Cytometry Society Continuing Education Program. Peer-reviewed continuing education and assessment program. September 2013;1-49.
2. * Li H, Olteanu H. Pure Erythroid Leukemia Evolving from Chronic Myeloproliferative Neoplasm Society for Hematopathology Case of the Quarter. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. September 2014;
3. * Schelling L, Olteanu H. Peripheral T-cell Lymphoma, Not Otherwise Specified with Germinal Center Phenotype Society for Hematopathology Case of the Quarter. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. May 2015;1-15.
4. Bradley K, Olteanu H. Dapsone-Associated Oxidant Hemolysis College of American Pathologists HE-B 2016 Proficiency Testing Program. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. April 2016;1-19.
5. Olteanu H. Acute Myeloid Leukemia College of American Pathologists VPBS-B 2017 Proficiency Testing Program. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. April 2017;
6. Olteanu H, Fuda F, Montgomery R, Bass J, Pillai V. Flow Cytometric Applications in the Diagnosis of Acute Myeloid Leukemia International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. April 2017;1-24.
7. Olteanu H. High-grade B-cell lymphoma, with MYC and BCL-2 or BCL-6 rearrangements College of American Pathologists HPATH-A 2017 Program. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. April 2017;1-28.
8. * Fuda F, Shaver A, League SC, Montgomery R, Bass J, Olteanu H. Early T-Cell Precursor Acute Lymphoblastic Leukemia International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. October 2017;1-26.
9. Olteanu H, Fuda F, Shaver A, League SC, Montgomery R, Bass J. Angioimmunoblastic T-Cell Lymphoma International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. December 2017;1-26.
10. League SC, Montgomery R, Bass J, Fuda F, Shaver A, Olteanu H. Quantitation Methods by Flow Cytometry International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. May 2018;1-10.
11. Olteanu H, Fuda F, Shaver A, League SC, Montgomery R, Bass J. Gating / Analytic Strategies for Diagnostic Flow Cytometry in Patients with Hematologic Malignancies Treated with Monoclonal Antibodies International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. September 2018;1-24.
Abstracts 1. Zhang W, Braun A, Bauman Z, Olteanu H, Banerjee R. Profiling four homocysteine-related enzymes in the
NCI60 human cancer cell lines. Molecular & Cellular Proteomics. 2004; 3(10):S194. 2. Olteanu H, Karandikar NJ, McKenna RW, Xu Y. Differential utility of various markers in the flow cytometric
detection of paroxysmal nocturnal hemoglobinuria (PNH) in blood and marrow. Modern Pathology. 2006; 19:240A-241A.
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3. Olteanu H, Wang H, Chen W, McKenna RW, Karandikar NJ. Immunophenotypic identification of high-risk monoclonal gammopathy of undetermined significance. Laboratory Investigation. 2007; 87:255A.
4. Olteanu H, Karandikar NJ, Kroft SH. Clinical and laboratory findings in CD4(+) large granular lymphocyte leukemia. Laboratory Investigation. 2008; 88:268A.
5. * Walters MP, Olteanu H, VanTuinen P, Kroft SH. CD23 Expression in Plasma Cell Myeloma Is Specific for Abnormalities of Chromosome 11, and Is Associated with Primary Plasma Cell Leukemia in This Cytogenetic Sub-Group. Modern Pathology. 2009; 22:289A.
6. Olteanu H, Hari P, Schur BC, Kroft SH. Expression of Natural Killer Receptors in T Lymphocytes and NK Cells Post Stem Cell Transplantation. Modern Pathology. 2009; 22:385A-386A.
7. Harrington AM, Olteanu H, Kroft SH. The Specificity of Immunophenotypic Alterations in Blasts in Non-Acute Myeloid Disorders. Modern Pathology. 2009; 22:265A.
8. Harrington AM, Currey AD, Olteanu H, Kroft SH. Persistent Localized Bone Marrow Aplasia Following Radiotherapy With Preserved Peripheral Counts: A Study of Seven Cases. American Journal of Clinical Pathology. 2009; 132(4):631.
9. Olteanu H, Harrington A, George B, Bredeson C, Hari PN, Kroft SH. High Prevalence of Dapsone-Induced Oxidant Hemolysis in North American Stem Cell Transplant Recipients without Glucose-6-Phosphate-Dehydrogenase Deficiency. Blood. 2009; 114(22):1285.
10. Harrington AM, Olteanu H, Kroft SH. A Dissection of the CD45/Side Scatter (SS) Blast Gate in Non-Acute Myeloid Disorders and Non-Neoplastic Bone Marrows. Modern Pathology. 2010; 23:301A.
11. Olteanu H, Harrington AM, Kroft SH. CD23(+) Follicular Lymphoma: Immunophenotypic and Clinical Features. Modern Pathology. 2010; 23:315A.
12. * Spears MD, Olteanu H, Kroft SH, Harrington AM. Immunophenotypic Stability in Plasma Cell Myeloma by Flow Cytometry. Modern Pathology. 2010; 23:323A.
13. * Spears MD, Harrington AM, Kroft SH, Olteanu H. Immunophenotypic Stability of T-Cell Large Granular Lymphocytic Leukemia and Chronic Lymphoproliferative Disorders of NK Cells by Flow Cytometry. Modern Pathology. 2010; 23:323A.
14. Harrington AM, Olteanu H, Kroft SH. Incidental, Immunophenotypically Aberrant Cytotoxic T-Cell Clones in Patients with Other Hematologic Malignancies. Modern Pathology. 2010; 23:301A.
15. Vaughan J, Olteanu H, Wimpee B, Kroft SH, Jarzembowski JA. The Regulatory T-Lymphocyte Content of Post-Transplant Lymphoproliferative Disorders. Modern Pathology. 2010; 23:326A.
16. Olteanu H, Harrington AM, Kroft SH. The Role of Flow Cytometry in the Diagnosis of Intraocular Lymphoma. Modern Pathology. 2010; 23:383A.
17. Olteanu H, Schur CB, Harrington AM, Kroft SH. Time and Temperature Stability of T-Cell Subsets. Modern Pathology. 2010; 23:436A-437A.
18. Cogbill CH, Spears MD, Harrington AM, Olteanu H, Kroft SH. Analysis of Variables Affecting the Flow Cytometric Recovery of Plasma Cell Myeloma Cells in Bone Marrow Aspirates. Modern Pathology. 2011; 24:291A.
19. Olteanu H, Harrington AM, Kroft SH. CD200 Expression in Plasma Cell Myeloma. Modern Pathology. 2011; 24:312A-313A.
20. Rathke SK, Olteanu H, Kroft SH, Harrington AM. CD45 Expression in Plasma Cell Myeloma: Comparison of Flow Cytometry and Immunohistochemistry and Relationship to Prognostic Factors. Modern Pathology. 2011; 24:317A.
21. * Buonaccorsi JN, Kroft SH, Harrington A, VanTuinen P, Olteanu H. Clinicopathologic Analysis of the Impact of CD23 Expression in Plasma Cell Myeloma with t(11;14)(q13;q32). Modern Pathology. 2011; 24:288A.
22. * Horna P, Olteanu H, Kroft S, Harrington A. Flow Cytometric Analysis of Light Chain Expression Patterns in B-cell Lymphomas Using Monoclonal and Polyclonal Antibodies. Mod Pathol. 02/01/2011; 24(1s):301A. Abstract no. 1282.
23. * Vaughan J, Harrington AM, Kroft SH, Olteanu H. Immunophenotypic Stability of Sezary Cells by Flow Cytometry. Modern Pathology. 2011; 24:326A.
24. * Schur BC, Harrington AM, Kroft SH, Olteanu H. Lymphocyte Subset Reference Ranges for Evaluation of Immune Reconstitution after Allogeneic Stem Cell Transplantation. Modern Pathology. 2011; 24:455A.
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25. Chang JC, Harrington AM, Olteanu H, Kroft SH. Proliferation Centers in Bone Marrows Involved by Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Clinicopathologic Analysis. Modern Pathology. 2011; 24:289A.
26. * Harrington AM, Olteanu H, Eshoa C, Kroft SH. The Unique Immunophenotype of "Double-Hit Lymphomas". Modern Pathology. 2011; 24:300A.
27. Vaughan J, Olteanu H, Kroft SH, Harrington AM. Blast Immunophenotypes by Flow Cytometry in Acute Myeloid Leukemia with Myelodysplasia-Related Changes. Modern Pathology. 2012; 25:377A.
28. Olteanu H, Harrington AM, Kroft SH. CD200 Expression in Non-Myeloma Immunoproliferative Disorders. Modern Pathology. 2012; 25:358A-359A.
29. Vaughan J, Olteanu H, Kroft SH, Harrington AM. Flow Cytometric Blast Immunophenotype in Acute Myeloid Leukemias Arising from Non-Acute Myeloid Disorders. Modern Pathology. 2012; 25:378A.
30. * Parsons LN, Olteanu H, Kroft SH, Harrington AM. Megakaryocytic Hyperplasia Associated with Granulocyte-Colony Stimulating Factor. Modern Pathology. 2012; 25:360A.
31. Rathke SK, Olteanu H, Kroft SH, Harrington AM. Morphologic Changes in Myelodysplastic Syndrome Treated with Hypomethylating Agents. Modern Pathology. 2012; 25:364A.
32. Harrington AM, Olteanu H, Kroft SH. Most Diffuse Large B-Cell Lymphomas Are Identified by Flow Cytometry. Modern Pathology. 2012; 25:339A.
33. Olteanu H, Harrington AM, Kroft SH, Karandikar NJ, Fuda FF. The Prevalence of CD56 Expression by Flow Cytometry in Acute Promyelocytic Leukemia Patients Treated with All-Trans Retinoic Acid and Anthracycline Drug Combinations. Modern Pathology. 2012; 25:359A.
34. * Horna P, Kroft SH, Harrington AM, Olteanu H. Persistence of Residual Normal Peripheral Blood B Cells in Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Identifies a Good Prognostic Subgroup. Mod Pathol. 02/01/2012; 25(S2):341A. Abstract no. 1428.
35. Vaughan J, Harrington A, Olteanu H, Kroft SH, Hess MA, Miller RA. A Retrospective Analysis of the Utility of Pathology Review Criteria for Peripheral Blood and Body Fluids: One Institution's Experience. American Journal of Clinical Pathology. 2012; 138:A087.
36. * Vaughan J, Mackinnon AC, Harrington AM, Kroft SH, Olteanu H. CD200 Expression in Post-Transplant Lymphoproliferative Disorders Correlates with an Increased Frequency of FoxP3(+) Regulatory T-Cells. Modern Pathology. 2013; 26:365A.
37. * Hintzke M, Fenske T, Kroft SH, Olteanu H, Harrington AM. CD30 Expression in Non-Hodgkin B-Cell Lymphoma. Modern Pathology. 2013; 26:331A-332A.
38. Rathke SK, Harrington AM, Olteanu H, Kroft SH. Dim CD33 Expression in Myelomonocytic Marrow Elements: A Novel Description of an Apparently Normal Variant. Modern Pathology. 2013; 26:356A-357A.
39. * Schumann J, Harrington AM, Kroft SH, Olteanu H. NK Cell Reference Ranges Established by Flow Cytometry in Reactive and Lymphomatous Lymph Nodes. Modern Pathology. 2013; 26:360A.
40. Rathke SK, Chang JC, Harrington AM, Olteanu H, Kroft SH. The Immunophenotype of Prolymphocytoid Transformation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Revisited. Modern Pathology. 2013; 26:357A.
41. Olteanu H, Vaughan J, Kroft SH, Fuda F, Harrington AM. Immunophenotypic Analysis of Mycosis Fungoides in Large Cell Transformation. American Journal of Clinical Pathology. 2013; 140:129.
42. Ordobazari A, Olteanu H, Kroft SH, Harrington AM. A Comparison of Therapy-Related and De Novo Chronic Myelomonocytic Leukemia. Modern Pathology. 2014; 27:369A.
43. * Li H, Kroft SH, Harrington AM, Hosking P, Olteanu H. Pure Erythroid Leukemia Evolving from Chronic Myeloid Neoplasms: A Report of 3 Cases. Modern Pathology. 2014; 27:357A-358A.
44. * Batdorf B, Kroft S, Hosking P, Harrington A, Mackinnon A, Olteanu H. Evaluation of CD43 Expression in Non-Hematologic Malignancies. American Journal of Clinical Pathology. 2014; 142.
45. Batdorf B, Kroft S, Olteanu H, Harrington A. Reactive Bone Marrow Plasmacytosis: An Update for the Modern Era. American Journal of Clinical Pathology. 2014; 142.
46. Hintzke M, Olteanu H, Kroft SH, Harrington AM. Sensitivity and Specificity of Peripheral Blood Findings in Screening for Myelodysplastic Syndrome. American Journal of Clinical Pathology. 2014; 142.
47. Merzianu M, Cheney R, Groman A, Deeb G, Wilding G, Cotta C, Amre R, Balasubramanian M, Brandao G, Brynes R K, Cherian S, Courville E, Czuchlewski D, Fan G, Grier D, Hoehn D, Hutchison RE, Inamdar KV,
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Juskevicius R, Kaur P, Lazarchick J, Lewis MR, Miles RR, Myers JB, Nasr M, Naushad H, Olteanu H, Orazi A, Reddy VVB, Robu VG, Salaru G, Teruya-Feldstein J, Vajpayee N, Vos J, Zhang L, Zhang SX, Sedelmeyer AV, Arguello V, Aye L, Barouk S, Brega EF, Carpenter R, Coad JE, DiPonio A, Garcia F, Grantham J, Ivelja S, McKenna R, Sultan K, Thomsen MB, Xu J, Peterson L, Neppalli VT. Bone Marrow Core Biopsy Adequacy and Variability in the United Stated and Canada: A Multicenter Retrospective Study. Blood. 2014; 124(21).
48. Harrington A, Shewmake A, Hosking P, Olteanu H, Kroft S. CD3 Staining on Myeloid Elements in Acute Myeloid Leukemia Bone Marrows. Modern Pathology. 2015; 28:348A.
49. * Hartley C, Hintzke M, Vaughan J, Hosking P, Harrington A, Kroft S, Olteanu H. CD30 Expression in Post-Transplant Lymphoproliferative Disorders. Modern Pathology. 2015; 28:349A.
50. * Li H, Kroft SH, Harrington AM, Hosking P, Olteanu H. CD38 Expression in Follicular Lymphoma Correlates With Histologic Grade. Modern Pathology. 2015; 28:359A.
51. * Robin A, Kroft SH, Harrington AM, Hosking P, Olteanu H. Evaluation of Proliferation Index in Lymph Nodes With CLL/SLL. Modern Pathology. 2015; 28:374A.
52. Harrington AM, Olteanu H, Hosking P, Kroft S. Unique Aberrant Myeloblast Immunophenotype Associated With Azathioprine Therapy. Modern Pathology. 2015; 28:349A.
53. Hintzke M, Hosking P, Olteanu H, Harrington A, Kroft SH. Bone Marrow Monocytosis: A Survey of 150 Cases. American Journal of Clinical Pathology. 2015; 144:A150.
54. Schelling L, Ordobazari A, Kroft SH, Olteanu H, Hosking P, Harrington AM. Immunophenotypic Comparison of Dysplastic and Proliferative Subtypes of Chronic Myelomonocytic Leukemia by Flow Cytometry. American Journal of Clinical Pathology. 2015; 144:A161.
55. * Batdorf B, Gheorghe G, Kroft S, Harrington A, Olteanu H, Hosking P. Correlation of CD79a Expression with Additional B-Cell Markers and Bruton's Tyrosine Kinase Expression in T-Cell Lymphoblastic Leukemia/Lymphoma. Modern Pathology. 2016; 29:335A.
56. Olteanu H, Hosking P, Harrington AM, Kroft SH. PD-L1 Expression Correlates with EBV Status in Post-Transplant Lymphoproliferative Disorders. Modern Pathology. 2016; 29:366A.
57. Olteanu H, Mboko W, Tarakanova V, Hosking P, Harrington AM, Kroft SH. Tumor Suppressor IRF-1 Expression Is Decreased in Post Transplant Lymphoproliferative Disorder. Modern Pathology. 2016; 29:366A.
58. * Epperla N, Fenske TS, Olteanu H, Pruett J, Goff A, Zellner K, Hamadani M, Shah NN. Outcomes of Grade 3A Follicular Lymphoma: Best Treated As Aggressive or Indolent Lymphoma? Blood. 2016; 128(22).
59. Kharfan-Dabaja MA, Raj RV, El-Jurdi N, Majhail N, Kumar A, Darrah J, Ayala E, de Lima M, Nishihori T, Parameswaran NH, Olteanu H, Zhang L, Sokol L, Hamadani N, Al-Malki M. A multicenter retrospective study of allogeneic hematopoietic cell transplantation in blastic plasmacytoid dendritic cell neoplasm. Bone Marrow Transplantation. 2017; 52:S386-S387.
60. Hopp AM, Olteanu H, Harrington AM, Kroft SH. Comparative Evaluation of Plasmacytoid Dendritic Cell Content in Reactive and Neoplastic Lymphoid Aggregates in Bone Marrow (BM). Modern Pathology. 2018; 31:522.
61. * Carrillo LF, Mendoza D, Olteanu H, Harrington A, Kroft SH. Computer-Based Differential Tally Counter for Bone Marrows. Modern Pathology. 2018; 31:585.
62. Carrillo LF, Harrington A, Olteanu H, Kroft SH. Evaluation of Extranodal Marginal Zone B Cell Lymphoma by Flow Cytometry. Modern Pathology. 2018; 31:503-504.
63. Olteanu H. Comparative evaluation of flow cytometry (fc) and morphology for detecting malignant cells in cerebrospinal fluid (csf) from patients with known hematologic neoplasms Laboratory Investigation. 2019 Mar; 99(Suppl 1):1351
64. Horna P, Shi M, Jevremovic D, Olteanu H. Single-Antibody Detection of T-Cell Receptor Beta Chain Monotypia Resolves Uncertainties in the Identification and Quantitation of Sézary Cells By Routine Flow Cytometry: Towards Accurate and Unequivocal Blood Staging of Cutaneous T-Cell Lymphomas Blood. 2019.
65. Shi M, Olteanu H, Jevremovic D, He R, Viswanatha D, Corley H, Horna P. Clinical utility of t-cell receptor constant beta chain-1 staining in the diagnosis of t-cell large granular lymphocytic leukemia by flow cytometry Laboratory Investigation. 2020 Mar; 100(SUPPL 1):1384-5
66. Berg H, Shi M, Horna P, Jevremovic D, Corley H, Otteson G, Olteanu H. Flow cytometric evaluation of trbc1 expression in tissue specimens and body fluids is a novel, sensitive and specific method for assessment of t-cell clonality and diagnosis of t-cell neoplasms Laboratory Investigation. 2020 Mar; 100(SUPPL 1):1255-6
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67. Qureshi R, Otteson G, Timm M, Shi M, Olteanu H, Kumar S, Jevremovic D. Quality parameters for flow cytometric minimal residual disease (mrd) assessment in plasma cell neoplasms Laboratory Investigation. 2020 Mar; 100(SUPPL 1):1367-8
68. Marissa Li, Terra Lasho, Alejandro Ferrer, Naseema Gangat, Aref Al-Kali, Abhishek Mangaonkar, Michelle Elliott, Mark Litzow, William Hogan, Animesh Pardanani, Alexandra Wolanskyj, Kaaren Reichard, Matthew Howard, Rebecca King, Mithun Shah, Hassan Alkhateeb, Kebede Begna, Ayalew Tefferi, Christy Finke, Moritz Binder, Horatiu Olteanu, Mrinal Patnaik. Clinical, Molecular, and Prognostic Comparisons between Clonal Cytopenias of Undetermined Significance and Lower-risk Myelodysplastic Syndromes - A Study of 184 Molecularly Annotated Patients 62nd ASH Annual Meeting. 2020.
69. Emma DiFilippo, Alejandro Ferrer, Laura Schultz-Rogers, Shakila Khan, Naseema Gangat, Aref Al-Kali, Abhishek Mangaonkar, Animesh Pardanani, Michelle Elliott, Mark Litzow, William Hogan, Alexandra Wolanskyj-Spinner, Phuong Nguyen, Kaaren Reichard, Matthew Howard, Rebecca King, Dong Chen, Rong He, David Viswanatha, Terra Lasho, Rajiv Pruthi, Pavel Pichurin, Teresa Kruisselbrink, Brendan Lanpher, Mark Wylam, Jennifer Oliveira, Dusica Babovic-Vuksanovic, Horatiu Olteanu, Mrinal Patnaik. Spectrum of Hematological Malignancies in 130 Patients with Germline Predisposition Syndromes- Mayo Clinic Germline Predisposition Study 62nd ASH Annual Meeting Abstract#: 139050. 2020.
Letters 1. Walters M, Olteanu H, Van Tuinen P, Kroft SH. CD23 expression in plasma cell myeloma is specific for
abnormalities of chromosome 11, and is associated with primary plasma cell leukaemia in this cytogenetic sub-group. Br J Haematol 2010 Apr; 149 (2):292-3 Epub 2010 Jan 08 PMID:20064156 DOI:10.1111/j.1365-2141.2009.08042.x
2. Morice WG, Jevremovic D, Olteanu H, Roden A, Nowakowski G, Kroft S, Hanson CA, Kurtin PJ. Chronic lymphoproliferative disorder of natural killer cells: a distinct entity with subtypes correlating with normal natural killer cell subsets. Leukemia 2010 Apr; 24 (4):881-4 Epub 2010 Jan 28 PMID:20111066 DOI:10.1038/leu.2009.304
3. Olteanu H, Harrington AM, Ramirez S, Kroft SH, Hari P. Efficacy and safety of long-term (>7 year) alemtuzumab therapy for refractory T-cell large granular lymphocytic leukaemia. Br J Haematol 2010 Aug; 150 (4):480-1 Epub 2010 Apr 28 PMID:20456357 DOI:10.1111/j.1365-2141.2010.08218.x
4. * Spears MD, Harrington AM, Kroft SH, Olteanu H. Immunophenotypic stability of T-cell large granular lymphocytic leukaemia by flow cytometry. Br J Haematol 2010 Oct; 151 (1):97-9 Epub 2010 July 16 PMID:20636433 DOI:10.1111/j.1365-2141.2010.08307.x
5. Harrington AM, Olteanu H, Kroft SH, Eshoa C. The unique immunophenotype of double-hit lymphomas. Am J Clin Pathol 2011 Apr; 135 (4):649-50 PMID:21411790 DOI:10.1309/AJCPL11MAHISIJBQ
6. Olteanu H, Harrington AM, Kroft SH. Immunophenotypic stability of CD200 expression in plasma cell myeloma. Am J Clin Pathol 2012 Jun; 137 (6):1013-4 PMID:22586062 DOI:10.1309/AJCP8TF3WUIWLZHU
7. Hari P, Raj RV, Olteanu H. Targeting CD38 in Refractory Extranodal Natural Killer Cell-T-Cell Lymphoma. N Engl J Med 2016 Oct 13; 375 (15):1501-1502 PMID:27732828 DOI:10.1056/NEJMc1605684
8. Kanate AS, DiGilio A, Ahn KW, Al Malki M, Jacobsen E, Steinberg A, Hamerschlak N, Kharfan-Dabaja M, Salit R, Ball E, Bashir Q, Cashen A, Couriel D, Diez-Martin J, Katsanis E, Linhares Y, Mori S, Nash R, Pawarode A, Perales MA, Phipps CD, Richman C, Savani BN, Shapira MY, Stiff P, Strair R, Fenske TS, Smith SM, Sureda A, Olteanu H, Hamadani M. Allogeneic haematopoietic cell transplantation for extranodal natural killer/T-cell lymphoma, nasal type: a CIBMTR analysis. Br J Haematol 2018 Sep; 182 (6):916-920 Epub 2017 Aug 02 PMID:28771676 DOI:10.1111/bjh.14879
Thesis 1. Olteanu H. Aquaporin-mediated water transport in erythrocyte membranes: A comparative NMR study in frog
and rainbow trout "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. September 1996;
2. Olteanu H. Biochemical studies of human methionine synthase reductase University of Nebraska - Lincoln, Lincoln, NE. May 2003;
Book Reviews 1. Olteanu H. Flow Cytometry in Clinical Diagnosis, 4th ed. Lab Medicine. 2008; 39(8):507.
* Indicates that the primary author was a mentee of this author.