Olteanu.pdf - International Clinical Cytometry Society

Throughout my career as a Hematopathologist, I have been passionate about volunteering for professional societies, in various areas of education, professional development and advocacy. In my clinical practice, I had the opportunity to serve as medical director for clinical flow cytometry laboratories, at academic institutions and reference laboratories, for more than a decade, and to oversee laboratory test development in a complex regulatory environment. At the same time, I had the privilege of overseeing or contributing to professional development activities by working with several major professional societies (ASCP, CAP, SH and ICCS). For the past several years, I volunteered as a member of the ICCS Education Committee and also chaired the e-learning subcommittee. More recently, I became a member of the Advocacy and Outreach Committees at ICCS and will be co-chairing the Advocacy session at this year’s ICCS annual meeting. In addition to my work with these committees, I am also an ad-hoc contributor to the Newsletter, Q&A and Video subcommittees of the ICCS.

Over the years, my strong interest in understanding the complex regulatory landscape, as it pertains to the clinical laboratory practice, and desire in promoting our profession to ensure a robust current and future pathology workforce, have provided me with the necessary background for continuing in a similar role at ICCS. Therefore, I would be honored and delighted to serve as a Senior Councilor for Advocacy for the Society.

Horatiu Olteanu - Statement of Interest

RE-AIMS 9/1/2021 9:59:14 AM

Curriculum Vitae and Bibliography

Horatiu Olteanu, MD, PhD

Personal Information Place of Birth: Medias, Romania Citizenship: United States of America Email Address: [email protected]

Present Academic Rank and Position

Co-Director - Cell Kinetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic

11/2018 - Present

Professor of Laboratory Medicine and Pathology - Mayo Clinic College of Medicine and Science

02/2019 - Present

Consultant - Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota

02/2021 - Present

Education Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania - MD, Doctorate of Medicine

09/1990 - 09/1996

"Nicolae Stancioiu" Heart Institute, Cluj-Napoca, Romania - Internship, Cardiothoracic Surgery

04/1997 - 03/1998

Robert Koch Hospital, Gehrden, Germany - Visiting Fellow, Cardiovascular Diseases Clinic

04/1998 - 06/1998

University of Nebraska Lincoln, Lincoln, Nebraska - Ph.D., Biochemistry 07/1998 - 06/2003

University of Texas Southwestern Medical Center, Dallas, Texas - Resident, Anatomic and Clinical Pathology

07/2003 - 06/2007

Medical College of Wisconsin Affiliated Hospitals, Milwaukee, Wisconsin - Fellow, Hematopathology

07/2007 - 06/2008

Certification

Board Certifications

American Board of Pathology Anatomic Pathology and Clinical Pathology 2007 - Present

Anatomic Pathology and Clinical Pathology/Hematology 2008 - Present

Licensure Kansas 0432133 (inactive) (Medical) 2006 - Present

Wisconsin 50870-020 (Medical) 2007 - Present

Minnesota 62881 (Medical) 2017 - Present

Honors and Awards Eli Lilly-Alsifcom Award for Outstanding Academic Performance - "Iuliu Hatieganu" University of Medicine and Pharmacy

05/1996

Milton E. Mohr Graduate Fellowship - University of Nebraska - Lincoln, Lincoln, Nebraska

03/2000

Bukey Memorial Graduate Fellowship - University of Nebraska - Lincoln, Lincoln, Nebraska

03/2001

Holling Family Teaching Assistant Award - University of Nebraska - Lincoln, Lincoln, Nebraska

03/2002

Predoctoral Fellowship - American Heart Association , Lincoln, Nebraska 01/2003


Page 2 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Folsom Distinguished Dissertation Award - University of Nebraska - Lincoln, Lincoln, Nebraska

05/2004

Third Place - Podium Competition, John R. Rainey, MD Residents'/Fellow's Seminar - Texas Society of Pathologists Annual Meeting

01/2007

MCW Outstanding Medical Student Teacher for 2008-2009 Pathology Course - Medical College of Wisconsin

12/2009

Distinguished Biochemistry Alumni Award - University of Nebraska - Lincoln, Lincoln, Nebraska

04/2013

Outstanding Faculty Service Award - Medical College of Wisconsin 08/2013

Previous Professional Positions and Major Appointments Hospital Staff - Children's Hospital of Wisconsin, Wauwatosa, Wisconsin 07/2008 - 02/2011

Assistant Professor of Pathology - Medical College of Wisconsin, Milwaukee, Wisconsin

07/2008 - 06/2012

Hospital Staff - Community Memorial Hospital, Menomonee Falls, Wisconsin 07/2008 - 02/2018

Hospital Staff - Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin 07/2008 - 02/2018

Medical Director - Diagnostic Flow Cytometry Laboratory - Wisconsin Diagnostic Laboratories, Milwaukee, Wisconsin

09/2008 - 02/2018

Flow Cytometry Rotation Director, Pathology Residency Program - Medical College of Wisconsin, Milwaukee, Wisconsin

07/2011 - 02/2018

Program Director, Hematopathology Fellowship - Medical College of Wisconsin, Milwaukee, Wisconsin

07/2011 - 02/2018

Hematopathology Rotation Director, Pathology Residency Program - Medical College of Wisconsin, Milwaukee, Wisconsin

07/2011 - 02/2018

Associate Professor of Pathology - Medical College of Wisconsin, Milwaukee, Wisconsin

07/2012 - 02/2018

Hospital Staff - St. Joseph's Hospital, West Bend, Wisconsin 07/2012 - 02/2018

Medical Director, Continuing and Professional Education - Medical College of Wisconsin, Milwaukee, Wisconsin

07/2016 - 02/2018

Hospital Staff - Children's Hospital of Wisconsin, Wauwatosa, Wisconsin 03/2017 - 02/2018

Senior Associate Consultant - Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota

02/2018 - 02/2021

Professional Memberships and Societies

Professional Memberships and Services

American Chemical Society Member 01/2000 - 12/2011

American Medical Association Member 07/2008 - 12/2010

American Society for Clinical Pathology Member 01/2005 - Present Pathologist Recertification Individualized Self-Assessment Examination (PRISE) Committee

Member 09/2009 - 09/2013 Chair 09/2013 - 12/2018

Association for Molecular Pathology Member 01/2020 - Present

College of American Pathologists Member 01/2005 - Present


Page 3 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Hematology and Flow Cytometry Laboratory Inspector 05/2006 - Present House of Delegates Alternate Member 04/2020 - Present Hematology and Clinical Microscopy Resource Committee (HCMRC)

Member 11/2015 - Present International Clinical Cytometry Society

Member 01/2014 - Present Advocacy Committee Member 03/2020 - Present Outreach Committee Member 03/2020 - Present 2016 Annual Meeting Program Committee

Member 01/2016 - 12/2016 2017 Annual Meeting Program Committee

Member 01/2017 - 12/2017 E-Learning Subcommittee

Chair 01/2016 - 12/2019 Education Committee

Member 12/2015 - 12/2019 International Society for Advancement of Cytometry

Member 01/2014 - Present Minnesota Medical Association

Member 07/2018 - Present North Texas Society of Pathologists

Member 01/2006 - 06/2007 Phi Lambda Upsilon, Chemical Honor Society

Member 01/2000 - 06/2003 Society for Academic Continuing Medical Education

Member 01/2016 - Present Annual Meeting Abstract Review Committee

Member 09/2016 - 12/2016 Society for Hematopathology

Member 01/2009 - Present Case of the Quarter (COQ)

Co-Chair 03/2013 - 03/2015 Chair 03/2015 - 03/2017

Education Committee Member 03/2013 - 03/2015

Texas Society of Pathologists Member 11/2003 - 06/2007

United States and Canadian Academy of Pathology Member 01/2005 - Present USCAP Annual Meeting Abstract Review Board, Hematopathology Section

Member 06/2015 - 10/2017 Zumbro Valley Medical Society

Member 07/2018 - Present

Journal Responsibilities

Journal Editorial Responsibilities

Laboratory Medicine Assistant Editor 08/2015 - 04/2019 Associate Editor 05/2019 - Present

Journal Other Responsibilities


Page 4 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Annals of Diagnostic Pathology Reviewer 04/2013 - Present

BMC Hematology Reviewer 01/2014 - Present

Clinical Case Reports Reviewer 01/2014 - Present

Clinical Chemistry and Laboratory Medicine Reviewer 04/2013 - Present

Clinical Epidemiology Reviewer 06/2013 - Present

Cytometry. Part B, Clinical Cytometry Reviewer 04/2013 - Present

Haematologica Reviewer 03/2009 - Present

International Journal of Laboratory Hematology Reviewer 07/2014 - Present

Journal of Clinical Laboratory Analysis Reviewer 10/2013 - Present

Journal of Hematology & Oncology Reviewer 09/2013 - Present

Laboratory Medicine Reviewer 03/2009 - Present

Oncotarget Reviewer 06/2015 - Present

Plos One Reviewer 08/2016 - Present

Education Interests and Accomplishments

Curriculum and Course Development Pathology reviews and updates: Benign Leukocyte Disorders Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Pathology reviews and updates: Myelodysplastic Syndromes Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Pathology reviews and updates: Acute Myeloid Leukemia Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Pathology reviews and updates: Acute Lymphoblastic Leukemia Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Pathology reviews and updates: Common Diagnostic Patterns by Flow Cytometry Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Pathology reviews and updates: Benign and Reactive Lymphadenopathies Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Pathology reviews and updates: Low-Grade B-cell Lymphomas I Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018


Page 5 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Pathology reviews and updates: Low-Grade B-cell Lymphomas II Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Hematopathology I AP/CP resident assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin

2011 - 2018

Hematopathology II AP/CP resident assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin

2011 - 2018

Flow Cytometry AP/CP resident assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin

2011 - 2018

Hematopathology Fellowship Diagnostic bone marrow and lymph node assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin

2011 - 2018

Hematopathology Fellowship Flow cytometry assessment and evaluation Medical College of Wisconsin Milwaukee, Wisconsin

2011 - 2018

Applications of Flow Cytometric Immunophenotyping for Medical Technologists Medical College of Wisconsin Milwaukee, Wisconsin

2015 - 2018

Teaching Biochemistry 433/833 Teaching assistant; 1 semester/year University of Nebraska - Lincoln Lincoln, Nebraska

1999 - 2001

Sophomore Pathology Course Small group discussion leader; 6 hours/year University of Texas Southwestern Medical Center Dallas, Texas

2006 - 2007

Pathology reviews and updates: Low-Grade B-cell Lymphomas I and II 2 hours/year microscope sessions; AP/CP Pathology residency program Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Unknown Slide Case Review 4 hours/year microscope sessions; AP/CP Pathology residency program Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

Pathology reviews and updates: Benign Leukocyte Disorders, Myelodysplastic Syndromes, Myeloproliferative Neoplasms, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Common Diagnostic Patterns by Flow Cytometry 6 hours/year lectures; AP/CP Pathology residency program Medical College of Wisconsin Milwaukee, Wisconsin

2008 - 2018

MCW M2 Medical Student Pathology Course: Reactive Leukocyte Disorders 1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin

2009 - 2012

MCW M2 Medical Student Pathology Course: Myelodysplastic Syndrome and Myleoproliferative Neoplasms

2009 - 2012


Page 6 of 36

RE-AIMS 9/1/2021 9:59:14 AM

1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin

MCW M2 Medical Student Pathology Course: Acute Myeloid Leukemia 1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin

2009 - 2012

MCW M2 Medical Student Pathology Course: Acute Lymphoblastic Leukemia 1 hour/year lecture Medical College of Wisconsin Milwaukee, Wisconsin

2009 - 2012

MCW M2 Pathways Hematology Module: Introduction to WBC Disorders, Reactive and Neoplastic Myeloid Processes, Targeted Leukemia Therapy 4 hours of lectures and team-based learning activities/year Medical College of Wisconsin Milwaukee, Wisconsin

2013 - 2018

Hematopathology Fellows 1 hour/week; Slide teaching/case signout Mayo Clinic Rochester, Minnesota

2018 - Present

Hematopathology rotating residents 5 hours/week; Slide teaching/case signout Mayo Clinic Rochester, Minnesota

2018 - Present

Academy of Educational Excellence

Excellence in Education Administration and Leadership at the Fellow level on this date June 2019

Mentorship Spears, Michael (Fellow) Description: Current Status: Staff Pathologist, Pathology Associates, Greenville, TX Outcome: Co-authored 3 abstracts; 3 poster presentations at international meetings (USCAP); co-authored 3 published research manuscripts

07/2008 - 06/2009

Davidson-Keup, Anna (Pre-Med Student) Description: UW-Milwaukee Pre-Med School Mentoring Program Current Status: Not known Outcome: Career advice

12/2008 - 01/2009

Vaughan, James (Resident and Fellow) Description: Current Status: Assistant Professor of Pathology, University of Tennessee Graduate School of Medicine, Knoxville, TN Outcome: Co-authored 8 abstracts; 8 poster presentations at national and international meetings (USCAP, ASCP); co-authored a published research manuscript; developed tissue microarray for SOX-11 antibody validation (first laboratory in the state of Wisconsin)

07/2009 - 06/2012

Horna, Pedro (Clinical Fellow) Description: Current Status: Consultant and Associate Professor of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Outcome: Co-authored 2 abstracts; 2 poster presentations at international meetings (USCAP); co-authored a published research manuscript

07/2010 - 06/2011

Buonaccorsi, Noelle (Resident) Description: Current Status: Staff Pathologist, OSF HealthCare, Peoria, IL Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP); co-authored a published research manuscript

07/2010 - 06/2011


Page 7 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Wilcox, Rebecca (Junior Faculty) Description: Current Status: Associate Professor of Pathology, University of Vermont College of Medicine, Burlington, VT Outcome: Co-authored 3 oral presentations at national meetings (ASCP); committee service for national Pathology organization (ASCP)

07/2010 - 06/2015

Plaza, Jose (Junior Faculty) Description: Current Status: Professor of Pathology and Dermatology, Ohio State University Wexner Medical Center, Columbus OH Outcome: Co-authored 3 oral presentations at national meetings (ASCP); co-authored a published research manuscript; committee service for national Pathology organization (ASCP)

07/2010 - 06/2016

Lloyd, Isaac (Medical Student) Description: Pathway mentor Current Status: Adjunct Assistant Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT Outcome:

10/2010 - 06/2012

Schumann, Joseph (Medical Student) Description: Pathway research mentor Current Status: Staff Physician, Ascension Medical Group, Greenville, WI Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP)

10/2010 - 06/2012

Parsons, Lauren (Resident) Description: Current Status: Assistant Professor of Pathology, Medical College of Wisconsin, Milwaukee, WI Outcome: Co-authored 2 abstracts and 2 poster presentations at international meetings (USCAP, ICCS); committee service for national Pathology organization (ASCP)

07/2012 - 06/2015

Batdorf, Bjorn (Resident and Fellow) Description: Current Status: Staff Pathologist, North Memorial Medical Center, Minneapolis, MN Outcome: Co-authored 6 abstracts and 6 poster presentations at national and international meetings (USCAP, ASCP, ICCS); co-authored 1 published research manuscript

01/2013 - 02/2018

Drobysheva, Anastasia (Visiting Fellow) Description: Visiting fellow mentor Current Status: Anatomic and Clinical Pathology Resident, UT Southwestern Medical Center, Dallas, TX Outcome:

05/2013

Hosking, Paul (Junior Faculty) Description: Current Status: Assistant Professor, University of Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY Outcome: Co-authored 12 abstracts and 12 poster presentations at national and international meetings (USCAP, ASCP); co-authored 5 published research manuscripts

07/2013 - Present

Hongmei, Li (Resident) Description: Current Status: Staff Pathologist, Quest Diagnostics/AmeriPath, Milwaukee, WI Outcome: Co-authored 2 abstracts and 2 poster presentations at international meetings (USCAP); co-authored 1 published research manuscript

07/2013 - 06/2016

Schelling, Lindsay (Fellow) Description: Current Status: Staff Pathologist, OSF Saint Anthony Medical Center, Rockford, IL Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP); co-authored 2 published manuscripts

07/2014 - 06/2015


Page 8 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Robin, Adam (Resident) Description: Current Status: Staff Pathologist, London, UK Outcome: Co-authored 2 abstracts and 2 poster presentations at international meetings (USCAP, SH/EAHP)

07/2014 - 06/2016

Gibson, Sarah (Junior Faculty) Description: Current Status: Associate Professor of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA Outcome: Committee service for national Pathology organization (Society for Hematopathology)

07/2014 - 06/2017

Hartley, Christopher (Resident) Description: Current Status: Senior Associate Consultant and Assistant Professor of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP); co-authored one published manuscript; committee service for national Pathology organization (ASCP)

07/2014 - 06/2018

Hintzke, Maria (Resident and Fellow) Description: Current Status: Staff Pathologist, Ochsner Health System, New Orleans, LA Outcome: Co-authored 5 abstracts and 5 poster presentations at national and international meetings (USCAP, ASCP, SH/EAHP)

07/2015 - 06/2016

Peterson, Jess (Junior Faculty) Description: Current Status: Consultant and Associate Professor of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Outcome: Co-authored 5 published research manuscripts

07/2015 - 06/2018

Foss, Halle (Medical Student) Description: Pathway research mentor Current Status: Medical Student, Medical College of Wisconsin, Milwaukee, WI Outcome:

10/2015 - 01/2016

Knous, Kort (Medical Student) Description: Global Health Scholarly Pathway Advisor and research mentor Current Status: Medical Student, Medical College of Wisconsin, Milwaukee, WI Outcome: Co-authored one abstract and poster presentation at international meeting (USCAP)

12/2015 - 06/2017

Academic Career Development Preparing Future Faculty Fellow University of Nebraska - Lincoln Lincoln, Nebraska

09/2001 - 05/2002

GME: The New Frontier MCWAH 2012 GME Retreat Medical College of Wisconsin, Wisconsin

10/2012

ASCP Spring Leadership Forum 2013 American Society for Clinical Pathology Miami, Florida

03/2013

Developing effective team-based learning and case-based learning modules Discovery Curriculum faculty meeting Medical College of Wisconsin, Wisconsin

05/2015

Increasing fatigue awareness and recognizing sleep deprivation in faculty and trainees Pathology Grand Rounds Medical College of Wisconsin, Wisconsin

08/2015


Page 9 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Giving effective and timely feedback to trainees Pathology Grand Rounds Medical College of Wisconsin, Wisconsin

05/2016

Effective milestone mapping, assessment and implementation for the Hematopathology fellowship Hematopathology Clinical Competency Committee meeting Medical College of Wisconsin, Wisconsin

08/2016

Curriculum development and self-assessment module evaluation for the 9th Annual Midwestern Conference 9th Annual Midwestern Conference: Update Course on Surgical Pathology Medical College of Wisconsin, Wisconsin

10/2016 - 10/2016

Pathways to Success and Vitality: Resilience and Growth MCW Faculty Career Development Committee meeting Medical College of Wisconsin, Wisconsin

03/2017

Society for Academic Continuing Medical Education 2017 SACME Annual Meeting Scottsdale, AZ, United States of America

05/2017 - 05/2017

Continuing education outcomes assessment MCW CME committee meeting Medical College of Wisconsin, Wisconsin

08/2017

Identifying and managing fatigue and burnout among learners Pathology Grand Rounds Medical College of Wisconsin, Wisconsin

08/2017

Effective milestone assessment and mapping strategies Clinical Pathology Division Meeting Medical College of Wisconsin, Wisconsin

08/2017

Developing clinically relevant learning outcomes Pathology Grand Rounds committee meeting Medical College of Wisconsin, Wisconsin

09/2017

Curriculum development and self-assessment module evaluation for the 10th Annual Midwestern Conference 10th Annual Midwestern Conference: Update Course in Surgical Pathology Medical College of Wisconsin, Wisconsin

09/2017 - 09/2017

Are conventional learning theories sufficient to guide multi-site complex educational interventions? SACME Virtual Journal Club

03/2018

Implications of UME and GME Outcomes-based Reform Efforts for CPD SACME Virtual Journal Club

04/2018


04/2018

The Practice and Improvement Gaps in Medical Practice and Medical Education: Insights from Implementation Science SACME Virtual Journal Club

05/2018

DLMP Faculty 15 - Wellness Hematopathology Education Oversight Committee Meeting Rochester, Minnesota

09/2018

DLMP Faculty 15 - Writing Effective Multiple Choice Questions Hematopathology Education Oversight Committee Meeting Rochester, Minnesota

10/2018

DLMP Faculty 15 - Active Learning Hematopathology Division Meeting

11/2018


Page 10 of 36

RE-AIMS 9/1/2021 9:59:14 AM

DLMP Faculty 15 - Poll Everywhere Education Oversight Committee Meeting Rochester, Minnesota

12/2018

Trainees' Perceptions of Feedback: Validity Evidence for Two FEEDME (Feedback in Medical Education) Instruments Education Science Journal Club Rochester, Minnesota

02/2019

Striving While Accepting: Exploring the Relationship Between Identity and Implicit Bias Recognition and Management Education Science Journal Club Rochester, Minnesota

03/2019

Data, Big and Small: Emerging Challenges to Medical Education Scholarship Education Science Journal Club Rochester, Minnesota

04/2019

DLMP Faculty 15 - Discussion & Inquiry Hematopathology Division Meeting

04/2019

Immuno-Oncology (IO) Change Makers Discussion Group and Leadership Cohort American Society for Clinical Pathology CME Program Chicago, Illinois

04/2019 - 06/2019

Exploring the relationship between examiners' memories for performances, domain separation and score variability. Education Science Journal Club Rochester, Minnesota

05/2019

Comparing resident – patient encounters and case presentations in a family medicine clinic. Education Science Journal Club Rochester, Minnesota

08/2019

Integrating Technology into Teaching: From the Big Auditorium to the Bedside. ACGME webcast Rochester, Minnesota

08/2019

Unconscious Bias Hematopathology Division Meeting

11/2019

Beyond the United States Medical Licensing Examination Score: Assessing Competence for Entering Residency. Education Science Journal Club Rochester, Minnesota

11/2019

Crucial Conversations Mayo Clinic Rochester, Minnesota

11/2019

It’s a Story, not a Study: How to write your medical education research so people will want to read it. Education Science & Scholarship Symposium Rochester, Minnesota

12/2019

Quantitative Data Analysis for Education Researchers: Fundamentals, Tips, and Tricks Education Science & Scholarship Symposium Rochester, Minnesota

12/2019

Whose work is it anyway? Teamwork, collective competence, and the myth of individual performance assessment Education Grand Rounds Rochester, Minnesota

12/2019

Cognition, Mindsets and Well-Being ACGME Grand Rounds webinar Rochester, Minnesota

01/2020


Page 11 of 36

RE-AIMS 9/1/2021 9:59:14 AM

DLMP Faculty 15: Writing Letters of Reference for Residents and Fellows Hematopathology Division Meeting Rochester, Minnesota

01/2020

Education Science Journal Club Education Science Journal Club Rochester, Minnesota

01/2020

DLMP Faculty 15: Social Media - Twitter Hematopathology Division Meeting Rochester, Minnesota

02/2020

Education & Technology Forum 2020 Education & Technology Forum 2020 Rochester, Minnesota

02/2020

Education Science Journal Club Education Science Journal Club Rochester, Minnesota

02/2020

Education Grand Rounds: Validation of learner assessments: State of the art and future directions Education Grand Rounds Rochester, Minnesota

02/2020


03/2020 - 04/2020

Education Grand Rounds: Assessing Clinical Reasoning: Simulation and Beyond Dr. Rachel Yudkowsky as the 2020 Simulation Center Visiting Professor: Education Grand Rounds: Assessing Clinical Reasoning: Simulation and Beyond Rochester, Minnesota

04/2020

Faculty/Staff Development Series - 'COVID-19 and Wellbeing: Lessons learnt and Moving Forward'- Zoom Meeting COVID -19 led to enhanced wellbeing resources being made available for staff, trainees and faculty in the face of emerging stressors. The continued pandemic, and projected post pandemic phase heightens the need to review and strengthen wellbeing related interventions. This session will focus on:•Reviewing what helped you and your trainees to cope. •Sharing themes that have emerged in emerging empirical studies on mental health effects of COVID-19. •Brainstorming what can be done/offered in future at the programmatic and individual level.•Review of some cognitive and emotional tools to enhance resiliency. Rochester, Minnesota

06/2020

Crossing the Virtual Chasm: Rethinking Curriculum, Competency, and Culture in the Virtual Care Era Rochester, Minnesota

09/2020

Education Science Journal Club Social and Scholarship Hour Rochester, Minnesota

10/2020

Education Grand Rounds: Pivots in Health Professions Education: Advancing and Enhancing our Learning Environment Learn about Telehealth Education, Advancing Digital Engagement, Equity, Diversity, Inclusion, and Anti-Racism Curriculum Rochester, Minnesota

10/2020

Education Science Journal Club Rochester, Minnesota

11/2020

Education Grand Rounds: Emerging Online Learning Trends for Health Professional Education

11/2020

Education Grand Rounds Education Science and Scholarship Symposium (ESSS) Rochester, Minnesota

12/2020


Page 12 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Education Science Journal Club & ESSS Education Science Journal Club & ESSS Rochester, Minnesota

12/2020

ESSS | Poster & Works In Progress Session ESSS | Poster & Works In Progress Session Rochester, Minnesota

12/2020

Education and Technology Forum 2021 - Mayo Clinic Education and Technology Forum 2021 Rochester, Minnesota

02/2021

2021 Findling Lecture: Education Scholarship Event- Mayo Clinic 2021 Findling Lecture: Education Scholarship Event- Mayo Clinic Rochester, Minnesota

02/2021 - 02/2021

Fundamentals for Medical Education (Fun 4 ME) Fundamentals for Medical Education (Fun 4 ME) is designed for health care professionals either new to educationor who have some experience and are looking to hone their skills, reinforce best practices, and learnnew strategies within health professions, education, and assessment. Mayo Clinic Academy of Educational Excellence Professional Development Rochester, Minnesota

08/2021 - 08/2021

2021 Annual Association for Medical Education in Europe (AMEE): The Virtual Conference- Redefining Health Professions Education Together The AMEE conference is the leading annual event for all involved in medical and healthcare professions education. 2021 AMEE: The Virtual Conference- Redefining Health Professions Education Together Rochester, Minnesota

08/2021 - 08/2021

Educational Activities Innovative activities for resident/other trainee education in Hematopathology: 1) Created curriculum and evaluations based on new ACGME milestones for Hematopathology I, Hematopathology II, and Flow Cytometry AP/CP residency rotations, 2) Provided and created proficiency testing (PT) boot camp education for first year AP/CP residents, 3) Created Flow Cytometry trainee education modules, 4) Developed Hematopathology and Flow Cytometry examination, 5) Created Hematology/Flow Cytometry/Coagulation laboratory rounds for residents and fellows, 6) Provide education to a variety of individuals including pathology residents, Hematopathology fellows, Surgical Pathology fellows, other subspecialty pathology fellows, Hematology/Oncology fellows, medical students, Pathology observers, and laboratory professionals. Innovative activities for the Hematopathology Fellowship include: 1) Implemented Fellowship milestones July 2016, 2) Performed gap analysis of Hematopathology fellowship program, 3) Developed and implemented new rotation evaluations to align with ACGME milestones, 4) Formed Hematopathology Clinical Competency Committee (CCC), 5) Created and implemented formal fellow orientation with manual (over 50 type-written pages) 6) Developed Hematopathology fellowship employer survey, 7) Created transitions of care policy for Hematopathology fellows, 8) Created graduated (progressive) responsibility management policy for Hematopathology fellows, 9) Updated internal and external Hematopathology fellowship websites. Other innovative activities include: 1) Developed and implemented four Hematopathology-related modules (General Hematopathology, Bone Marrow, Lymph Node and Spleen, Flow Cytometry) for the Pathologist Recertification Individualized Self-Assessment Examination (PRISE) committee of the American Society for Clinical Pathology (ASCP); this is an online, modular, personal self-assessment, and comprehensive education tool specifically designed for practicing pathologists and Pathology residents, 2) Contributed personally 357 multiple choice questions to the 2011-2017 PRISE modules, 3) Developed and implemented a novel interactive format with CME and self-assessment module (SAM) credits for the Case of the Quarter e-learning activity of the Society for Hematopathology (SH), 4) Developed and implemented a novel format of e-learning activities for the International Clinical Cytometry Society (ICCS), 5) Developed and reviewed educational material, and submitted annual audit evaluations to the American Board of Pathology (ABP) to maintain the status of approved SAM provider for the MCW Department of Pathology, 6) Formed a formal MCW Pathology Grand Rounds committee as a venue to oversee, discuss, implement and continuously improve and innovate the delivery of Pathology education, 7) Re-organized and chaired the MCW CME committee, that developed and implemented a critical Responsible Opioid Prescribing Guideline CE course required by the state of Wisconsin Medical Board; developed and implemented new application guidelines for recurring CE activities, to better align with ACCME requirements; developed new outcome assessment tools and evaluations for CE activities, to better align with departmental and


Page 13 of 36

RE-AIMS 9/1/2021 9:59:14 AM

institutional quality indicators; implemented a major upgrade of EthosCE, the MCW institutional learning management platform; developed the first major strategic planning initiative for the Office of Continuing and Professional Education at MCW to map out the needs of its learners as it transforms into a health sciences university.

Institutional/Departmental Administrative Responsibilities, Committee Memberships and Other Activities

Mayo Clinic

DLMP Portfolio Prioritization Panel Member 06/2018 - Present

DLMP SoftFlow Oversight Subcommittee Member 09/2019 - Present

Education Oversight Committee, Division of Hematopathology Member 03/2018 - Present

Mayo Clinic in Rochester

Department of Laboratory Medicine and Pathology Division of Hematopathology

Myeloid Working Group Chair 07/2019 - Present

Activities at Other Institutions

Medical College of Wisconsin (MCW) Clinical Competency Committee, MCW Hematopathology Fellowship

Chair 03/2015 - 02/2018 Continuing Medical Education Committee, MCW Faculty Council

Member 07/2011 - 06/2014 Member 06/2015 - 06/2016

Faculty Climate Focus Group Member 06/2011

Grand Rounds Committee, MCW Department of Pathology Chair 04/2016 - 02/2018

Hematologic Malignancy Conference, MCW Department of Pathology Activity Director 11/2011 - 02/2018

Hematopathology Faculty Search Committee Member 05/2013 - 06/2013 Member 05/2016 - 12/2016

Institutional Review Board Committee #2 Ad Hoc Member 06/2014 - 02/2018

Institutional Review Board Committee #4 Member 01/2011 - 02/2018

Internal Review of the MCWAH Family Medicine - St. Joseph's Residency Program

Member 10/2012 - 11/2012 Internal Review of the MCWAH Hematology/Oncology Fellowship Program

Member 01/2008 MCW Cancer Center

Member 06/2011 - 02/2018 MCW Continuing Medical and Professional Education Committee

Chair 07/2016 - 02/2018 Medical College of Wisconsin, Institutional Review Board Committee #2

Ad Hoc Member 06/2016 - 02/2018


Page 14 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Wisconsin Diagnostic Laboratories Capital Steering Committee

Member 03/2012 - 02/2018 Communications Committee

Member 03/2014 - 12/2016 Dyad Operations Committee

Member 09/2011 - 02/2018 Quality Committee

Member 04/2017 - 02/2018

Presentations Extramural National or International

Invited

Reductive activation of methionine synthase: Purification and characterization of mammalian methionine synthase reductase FASEB Summer Research Conference "Folic Acid, Vitamin B12 and One Carbon Metabolism" Snowmass, Colorado

08/05/2000 - 08/10/2000

Effects of common polymorphisms on the activation of methioninesynthase by the dual flavoprotein oxidoreductase,methionine synthase reductase Gordon Research Conference " Enzymes , Coenzymes and Metabolic Pathways" Meriden, New Hampshire

07/20/2002 - 07/27/2002

Inflammatory Pseudotumor of Lymph Node Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

09/12/2008 - 09/14/2008

Blastic Plasmacytoid Dendritic Cell Neoplasm Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

08/21/2009 - 08/23/2009

Histiocytic Sarcoma Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

08/21/2009 - 08/23/2009

Flow Cytometry of Hodgkin Lymphoma Evening slide seminar The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

05/14/2010 - 05/16/2010

Case Study Interpretations 25th Annual International Clinical Cytometry Society Meeting Houston, Texas

10/03/2010 - 10/05/2010

Diffuse Large B-Cell Lymphoma: An Update on New Entities The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

09/09/2011 - 09/11/2011

Flow Cytometric Analysis in Myeloid Neoplasms 2011 ASCP Annual Meeting I WASPaLM XXVI World Congress Las Vegas, Nevada

10/19/2011 - 10/22/2011

Immunodeficiency-Associated Lymphoproliferative Disorders The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

09/14/2012 - 09/16/2012


Page 15 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Splenic Lymphomas: Classification and Advances in the Separation of Distinct Clinic pathologic and Molecular Entities -A SH/EAHP Workshop Proposal 2013 USCAP Annual Meeting Baltimore, Maryland

03/02/2013 - 03/08/2013

Maintenance of Certification and PRISE: Applying New and Validated Knowledge to Clinical Practice 2013 ASCP Annual Meeting Chicago, Illinois

09/18/2013 - 09/21/2013

Diagnostic Pitfalls in Reactive and Malignant Lymphadenopathies The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

09/20/2013 - 09/22/2013

Normal and Abnormal Immunophenotype Patterns by Flow Cytometry 2014 ASCP Annual Meeting Tampa, Florida

10/08/2014 - 10/10/2014

Problem Areas in the Interpretation of Lymph Node, Cutaneous, and Gastrointestinal l Biopsies - Presented by the Faculty of PRISE 2014 ASCP Annual Meeting Tampa, Florida

10/08/2014 - 10/10/2014

Diagnostic Challenges in Low-Grade B-Cell Lymphomas 2015 CAP Annual Meeting Nashville, Tennessee

10/04/2015 - 10/07/2015

Advanced Flow Cytometry-Based Diagnostic Hematopathology: An Integrated Approach 2015 ICCS Annual Meeting Denver, Colorado

10/11/2015 - 10/13/2015

Diagnostic Challenges in Low-Grade B-Cell Lymphomas 2016 CAP Annual Meeting Las Vegas, Nevada

09/25/2016 - 09/28/2016

Reactive Lymphoid Lesions vs. Low-Grade Lymphomas in Bone Marrow 2016 CAP Annual Meeting Las Vegas, Nevada

09/25/2016 - 09/28/2016

Advanced Flow Cytometry-Based Diagnostic Hematopathology 2016 ICCS Annual Meeting Bonita Springs, Florida

09/30/2016 - 10/04/2016

Have a Problem? Ask an Expert 2016 ICCS Annual Meeting Bonita Springs, Florida

09/30/2016 - 10/04/2016

38 Year-Old Patient with Extensive Lymphadenopathy Slide seminar: Problem Cases in Surgical Pathology The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

10/14/2016 - 10/16/2016

Diagnostic Challenges in CD5 (+) Low-Grade B-Cell Lymphomas The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

10/14/2016 - 10/16/2016

Clinical and Pathologic Features of Aggressive B-cell Lymphomas MEDLAB America Congress Orlando, Florida

08/08/2017 - 08/10/2017

Improving Efficiency in the Hematology Laboratory MEDLAB America Congress Orlando, Florida

08/08/2017 - 08/10/2017


Page 16 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Molecular Diagnosis in Complex Hematopathology Cases The Midwestern Conference - Update Course in Surgical Pathology Milwaukee, Wisconsin

09/15/2017 - 09/17/2017

Diagnostic Challenges in Low-Grade B-Cell Lymphomas 2017 CAP Annual Meeting National Harbor, Maryland

10/08/2017 - 10/11/2017

Diagnostic Challenges in Low-Grade B-Cell Lymphomas: Morphologic and Immunophenotypic Variants of CD5(+) Lymphoproliferative Disorders 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii

09/23/2019 - 09/27/2019

Diagnostic Challenges in Low-Grade B-Cell Lymphomas: Morphologic and Immunophenotypic Variants of Follicular Lymphoma 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii

09/23/2019 - 09/27/2019

Flow Cytometric Diagnosis of Complex Hematopathology Cases 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii

09/23/2019 - 09/27/2019

Flow Cytometric Evaluation of Mature T and NK-Cell Neoplasms: Integrating Morphology, Immunophenotype and Cytogenetic/Molecular Findings 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii

09/23/2019 - 09/27/2019

Flow Cytometric Evaluation of Plasma Cell Dyscrasias 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii

09/23/2019 - 09/27/2019

Flow Cytometry of Lymphoblastic Leukemias and Acute Leukemias of Ambiguous Lineage 2019 Hawaii Hematopathology Conference Kaanapali, Hawaii

09/23/2019 - 09/27/2019

Quality Parameters for Flow Cytometric Minimal Residual Disease (MRD) Assessment in Plasma Cell Neoplasms. 2020 USCAP Annual Meeting Los Angeles, California

02/29/2020 - 03/05/2020

Training Physician Extenders in the Clinical Practice of Diagnostic Hematopathology: A Novel Approach to Building Expertise and Improving Quality and Efficiency. 2020 USCAP Annual Meeting Los Angeles, California

02/29/2020 - 03/05/2020

Oral

Comparative Evaluation of Flow Cytometry (FC) and Morphology for Detecting Malignant Cells in Cerebrospinal Fluid (CSF) from Patients with Known Hematologic Neoplasms 2019 USCAP Annual Meeting National Harbor, Maryland

03/16/2019 - 03/21/2019

Single Antibody Assessment of T-Cell Clonality by Flow Cytometry Rapidly Identifies T-Cell Neoplasms and Monotypic CD8-Positive Subset of Uncertain Significance CYTO 2019: 34th Congress of the International Society of Advancement of Cytometry Vancouver, British Columbia, Canada

06/22/2019 - 06/26/2019

Flow Cytometric Evaluation of TRBC1 Expression in Tissue Specimens and Body Fluids is a Novel, Sensitive and Specific Method for Assessment of T-Cell Clonality and Diagnosis of T-Cell Neoplasms. 2020 USCAP Annual Meeting Los Angeles, California

02/29/2020 - 03/05/2020


Page 17 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Poster

Profiling four homocysteine-related enzymes in the NCI60 human cancer cell lines HUPO 3rd Annual World Congress Beijing, China

10/25/2004 - 10/27/2004

Differential utility of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and marrow 2006 USCAP Annual Meeting Atlanta, Georgia

02/11/2006 - 02/17/2006

Immunophenotypic identification of high-risk monoclonal gammopathy of undetermined significance 2007 USCAP Annual Meeting San Diego, California

03/23/2007 - 03/30/2007

Immunophenotype and Laboratory Findings in CD4(+) Large Granular Lymphocyte Leukemia 2008 USCAP Annual Meeting Denver, Colorado

03/01/2008 - 03/07/2008

CD23 expression in plasma cell rnyeloma is specific for abnormalities of chromosome 11, and is associated with primary plasma cell leukemia in this cytogenetic sub-group 2009 USCAP Annual Meeting Boston, Massachusetts

03/07/2009 - 03/13/2009

Expression of natural killer receptors in T lymphocytes and NK cells post stem cell transplantation 2009 USCAP Annual Meeting Boston, Massachusetts

03/07/2009 - 03/13/2009

The specificity of Immunophenotype alterations in blasts in non-acute myeloid disorders 2009 USCAP Annual Meeting Boston, Massachusetts

03/07/2009 - 03/13/2009

Gamma heavy chain disease SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio

09/24/2009 - 09/26/2009

IgM plasma cell myeloma SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio

09/24/2009 - 09/26/2009

Lymphoplasmacytic lymphoma with extensive plasmacytic differentiation and plasmablastic morphology SH/EAHP 2009 workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio

09/24/2009 - 09/26/2009

Plasmacytoid neoplasm with plasmablastic features SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms Cleveland, Ohio

09/24/2009 - 09/26/2009

Rapidly progressive fatal dementia secondary to lymphomatosis cerebri CAP Annual Meeting Washington, District of Columbia

10/11/2009 - 10/14/2009

Localized bone marrow aplasia following radiation with discrepant peripheral counts ASCP Annual Meeting Chicago, Illinois

10/28/2009 - 11/01/2009


Page 18 of 36

RE-AIMS 9/1/2021 9:59:14 AM

High prevalence of Dapsone-induced oxidant hemolysis in North American stem cell transplant recipients without glucose-6-phosphate -dehydrogenases deficiency 2009 ASH Annual Meeting New Orleans, Louisiana

12/05/2009 - 12/08/2009

A Dissection of the CD45/Side Scatter (SS) Blast Gate in Non-acute Myeloid Disorders and Non-neoplastic Bone Marrows 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

CD23(+) Follicular Lymphoma: Immunophenotypic and Clinical Features 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

Immunophenotypic Stability in Plasma Cell Myeloma by Flow Cytometry 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

Immunophenotypic Stability of T-Cell Large Granular Lymphocytic Leukemia and Chronic Lymphoproliferative Disorders of NK Cells by Flow Cytometry 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

Incidental, Immunophenotypically Aberrant Cytotoxic T-Cell Clones in Patients with Other Hematologic Malignancies 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

The Prevalence of Regulatory T-Lymphocytes in Post-Transplant Lymphoproliferative Disorders 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

The Role of Flow Cytometry in the Diagnosis of Intraocular Lymphoma 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

Time and Temperature Stability of T-Cell Subsets 2010 USCAP Annual Meeting Washington, District of Columbia

03/20/2010 - 03/26/2010

Analysis of Variables Affecting the Flow Cytometric Recovery of Plasma Cell Myeloma Cells in Bone Marrow Aspirates 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011

CD200 Expression in Plasma Cell Myeloma 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011

CD45 Expression in Plasma Cell Myeloma: Comparison of Flow Cytometry and Immunohistochemistry and Relationship to Prognostic Factors 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011

Clinic pathologic Analysis of the Impact of CD23 Expression in Plasma Cell Myeloma with t(l 1:14)(q13;q32) 2011 USCAP Annual Meeting, San Antonio, Texas

02/26/2011 - 03/04/2011

Flow Cytometric Analysis of Light Chain Expression Patterns in B-cell Lymphomas Using Monoclonal and Polyclonal Antibodies 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011


Page 19 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Immunophenotypic Stability of Sezary Cells by Flow Cytometry 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011

Lymphocyte Subset Reference Ranges for Evaluation of Immune Reconstitution After Allogeneic Stem Cell Transplantation 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011

Proliferation Centers in Bone Marrows Involved by Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Clinicopathologic Analysis 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011

The Unique Immunophenotype of Double-Hit Lymphomas 2011 USCAP Annual Meeting San Antonio, Texas

02/26/2011 - 03/04/2011

Blast Immunophenotypes by Flow Cytometry in Acute Myeloid Leukemia with Myelodysplasia-Related Changes 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

CD200 Expression in Non-Myeloma Immunoproliferative Disorders 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

Flow Cytometric Blast Immunophenotype in Acute Myeloid Leukemia Arising from Non-Acute Myeloid Disorders 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

Megakaryocytic Hyperplasia Associated with Granulocyte-Colony Stimulating Factor 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

Morphologic Changes in Myelodysplastic Syndrome Treated with Hypomethylating Agents 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

Most Diffuse Large B-Cell Lymphomas Are Identified by Flow Cytometry 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

Persistence of Residual Norma l Peripheral Blood B Cells in Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Identifies a Good Prognostic Subgroup 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

The Prevalence of CD56 Expression by Flow Cytometry in Acute Promyelocytic Leukemia Patients Treated with All-Trans Retinoic Acid and Anthracycline Drug Combinations 2012 USCAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2012 - 03/23/2012

A Retrospective Analysis of the Utility of Pathology Review Criteria for Peripheral Blood and Body Fluids: One Institution's Experience 2012 ASCP Annual Meeting Boston, Massachusetts

10/31/2012 - 11/03/2012

CD200 Expression in Post-Transplant Lymphoproliferative Disorders Correlates With an Increased Frequency of FoxP3(+) Regulatory T-Cells

03/02/2013 - 03/08/2013


Page 20 of 36

RE-AIMS 9/1/2021 9:59:14 AM

2013 USCAP Annual Meeting Baltimore, Maryland

CD30 Expression in Non-Hodgkin B-cell Lymphoma 2013 USCAP Annual Meeting Baltimore, Maryland

03/02/2013 - 03/08/2013

Dim CD33 Expression in Myelomonocytic Manow Elements: A Novel Description of an Apparently Normal Variant 2013 USCAP Annual Meeting Baltimore, Maryland

03/02/2013 - 03/08/2013

NK Cell Reference Ranges Established by Flow Cytometry in Reactive and Lymphomatous Lymph Nodes 2013 USCAP Annual Meeting Baltimore, Maryland

03/02/2013 - 03/08/2013

The Immunophenotype of Prolymphocytoid Transformation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Revisited 2013 USCAP Annual Meeting Baltimore, Maryland

03/02/2013 - 03/08/2013

Immunophenotypic Analysis of Mycosis Fungoides in Large Cell Transformation 2013 ASCP Annual Meeting Chicago, Illinois

09/18/2013 - 09/21/2013

A Comparison of Therapy-Related and De Novo Chronic Myelomonocytic Leukemia 2014 USCAP Annual Meeting San Diego, California

03/01/2014 - 03/07/2014

Pure Erythroid Leukemia Evolving from Chronic Myeloid Neoplasms: A Report of 3 Cases 2014 USCAP Annual Meeting San Diego, California

03/01/2014 - 03/07/2014

Evaluation of CD43 Expression in Non-Hematologic Malignancies 2014 ASCP Annual Meeting Tampa, Florida

10/08/2014 - 10/10/2014

Reactive Bone Marrow Plasmacytosis : An Update for the Modern Era 2014 ASCP Annual Meeting Tampa, Florida

10/08/2014 - 10/10/2014

Sensitivity and Specificity of Peripheral Blood Findings in Screening for Myelodysplastic Syndrome 2014 ASCP Annual Meeting Tampa, Florida

10/08/2014 - 10/10/2014

Flow Cytometric Analysis of CD23 and FMC-7 Expression in Diffuse Large B-Cell Lymphoma 2014 ICCS Annual Meeting Seattle, Washington

10/10/2014 - 10/14/2014

Bone Marrow Core Biopsy Adequacy and Variability in the United Stated and Canada: A Multicenter Retrospective Study 56th ASH Annual Meeting San Francisco, California

12/06/2014 - 12/09/2014

CD3 Staining on Myeloid Elements in Acute Myeloid Leukemia Bone Marrows 2015 USCAP Annual Meeting Boston, Massachusetts

03/21/2015 - 03/27/2015

CD30 Expression in Post-Transplant Lymphoproliferative Disorders 2015 USCAP Annual Meeting Boston, Massachusetts

03/21/2015 - 03/27/2015


Page 21 of 36

RE-AIMS 9/1/2021 9:59:14 AM

CD38 Expression in Follicular Lymphoma Correlates with Histologic Grade 2015 USCA P Annual Meeting Boston, Massachusetts

03/21/2015 - 03/27/2015

Evaluation of Proliferation Index in Lymph Nodes with CLL/SLL 2015 USCAP Annual Meeting Boston, Massachusetts

03/21/2015 - 03/27/2015

Novel morphologic finding and clinicopathologic features of acute myeloid leukemias and myelodysplastic syndromes with isolated trisomy 11 2015 USCAP Annual Meeting Boston, Massachusetts

03/21/2015 - 03/27/2015

Unique Aberrant Myeloblast Immunophenotype Associated with Azathioprine Therapy 2015 USCAP Annual Meeting Boston, Massachusetts

03/21/2015 - 03/27/2015

Bone Marrow Monocytosis: A Survey of 150 Cases 2015 ASCP Annual Meeting Long Beach, California

10/28/2015 - 10/30/2015

Immunophenotypic Comparison of Dysplastic and Proliferative Subtypes of Chronic Myelomonocytic Leukemia by Flow Cytometry 2015 ASCP Annual Meeting Long Beach, California

10/28/2015 - 10/30/2015

Donor- Derived Post-Transplant Lymphoproliferative Disorder following Stem Cell Transplantation SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation Long Beach, California

10/29/2015 - 10/31/2015

Monomorphic B-cell PTLD, Burkitt lymphoma SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation Long Beach, California

10/29/2015 - 10/31/2015

Monomorphic T --cell PTLD, Anaplastic large cell lymphoma, ALK (-) SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation Long Beach, California

10/29/2015 - 10/31/2015

Bone Marrow Biopsy Practice and Quality Trends in USA and Canada : A Retrospective Multicenter Study 2016 USCAP Annual Meeting Seattle, Washington

03/12/2016 - 03/18/2016

Correlation of CD79a Expression with Additional B-Cell Markers and Bruton's Tyrosine Kinase Expression in T-Cell Lymphoblastic Leukemia/Lymphoma 2016 USCAP Annual Meeting Seattle, Washington

03/12/2016 - 03/18/2016

PD-L1 Expression Correlates with EBV Status in Post-Transplant Lymphoproliferative Disorders 2016 USCAP Annual Meeting Seattle, Washington

03/12/2016 - 03/18/2016

Tumor Suppressor IRF-1 Expression is Decreased in Post-Transplant Lymphoproliferative Disorders 2016 USCAP Annual Meeting Seattle, Washington

03/12/2016 - 03/18/2016

Variability and Adequacy of Evaluable Marrow Space Length (EMSL) in Bone Marrow Biopsies: A Multi-institutional Study 2016 USCAP Annual Meeting Seattle, Washington

03/12/2016 - 03/18/2016


Page 22 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Reactivation of Pulmonary Tuberculosis after Use of Ruxolitib for Myelofibrosis AMMI Canada - CACMID Annual Conference Vancouver, British Columbia, Canada

03/30/2016 - 04/02/2016

A patient with a mediastinal mass with features of primary mediastinal B-cell lymphoma and an aggressive clinical course SH/EAHP 2016 Lymphoma Workshop Basel, Switzerland

09/03/2016 - 09/08/2016

Double-Hit" Diffuse Large B-cell Lymphoma With t(2;8), t(l 4;18) And Extensive Necrosis SH/EAHP 2016 Lymphoma Workshop Basel, Switzerland

09/03/2016 - 09/08/2016

Allogeneic Hematopoietic Cell Transplantation (alloHCT) for Extranodal Natural Killer (NK)/T-Cell Lymphoma, Nasal Type (ENKL): A CIBMTR Analysis 2017 EMT Tandem meetings Orlando, Florida

02/22/2017 - 02/26/2017

A Multicenter Study Evaluating the Efficacy of Allogeneic Hematopoietic Cell Transplantation (allo-HCT) in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) 43rd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMI 2017) Marseille, France

03/26/2017 - 03/29/2017

Prevalence and Diagnostic Utility of Dutcher Bodies in Orbital Biopsies 2017 CAP Annual Meeting National Harbor, Maryland

10/08/2017 - 10/11/2017

Comparative Evaluation of Plasmacytoid Dendritic Cell Content in Reactive and Neoplastic Lymphoid Aggregates in Bone Marrow 2018 CAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2018 - 03/23/2018

Computer-based Differential Tally Counter for Bone Marrows 2018 CAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2018 - 03/23/2018

Evaluation of Extranodal Marginal Zone B-cell Lymphoma by Flow Cytometry 2018 CAP Annual Meeting Vancouver, British Columbia, Canada

03/17/2018 - 03/23/2018

Diagnostic Utility of Cerebrospinal Fluid Flow Cytometry in Patients with Hematologic Malignancies 2018 ICCS Annual Meeting Portland, Oregon

09/28/2018 - 10/02/2018

Carcinocythemia: A Rare Entity Becoming More Common? A Case Series and Literature Review 2018 ASCP Annual Meeting Baltimore, Maryland

10/03/2018 - 10/05/2018

Development of a robust, highly sensitive and specific 10-color flow cytometry panel for minimal/measurable residual disease in acute myeloid leukemia. 34th Annual Clinical Cytometry Meeting and Course Atlanta, Georgia

10/06/2019 - 10/08/2019

Flow cytometric assessment of TRBC1 expression in tissue specimens is a novel, sensitive and specific method for evaluation of T-cell clonality and identification of T-cell neoplasms. 34th Annual Clinical Cytometry Meeting and Course Atlanta, Georgia

10/06/2019 - 10/08/2019


Page 23 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Single-Antibody Detection of T-Cell Receptor Beta Chain Monotypia Resolves Uncertainties in the Identification and Quantitation of Sézary Cells By Routine Flow Cytometry: Towards Accurate and Unequivocal Blood Staging of Cutaneous T-Cell Lymphomas. 61st ASH Annual Meeting Orlando, Florida

12/07/2019 - 12/10/2019

Clinical Utility of T-cell Receptor Constant ß Chain-1 Staining in the Diagnosis of T-cell Large Granular Lymphocytic Leukemia by Flow Cytometry. 2020 USCAP Annual Meeting Los Angeles, California

02/29/2020 - 03/05/2020

Algorithmic Diagnostic Approach and Spectrum of Hematological Malignancies in Patients with Germline Predisposition Syndromes Society of Hematologic Oncology Ninth Annual Meeting (SOHO 2021) Houston, Texas

09/08/2021 - 09/11/2021

BET Inhibitor Pelabresib Decreases Inflammatory Cytokines, Improves Bone Marrow Fibrosis and Function, and demonstrates Clinical Response Irrespective of Mutation Status in Myelofibrosis Patients in the Phase 2 MANIFEST Trial Society of Hematologic Oncology Ninth Annual Meeting (SOHO 2021) Houston, Texas

09/08/2021 - 09/11/2021

Artificial Intelligence-Assisted Classification Tool for Minimal Residual Disease (MRD) Assessment by Flow Cytometry in Patients with Acute Myeloid Leukemia (AML) 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland

10/08/2021 - 10/12/2021

Augmented human intelligence enhances flow cytometric (FC) analysis in the detection of minimal residual disease (MRD) of chronic lymphocytic leukemia (CLL) 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland

10/08/2021 - 10/12/2021

Augmented Human Intelligence Improves Diagnostic Workflow for Myelodysplastic Syndrome (MDS) Flow Cytometry (FC) Data Processing and Analysis 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland

10/08/2021 - 10/12/2021

Cluster-Based Analysis Training for Technologists Improves Accuracy and Understanding of Flow Cytometric Immunophenotyping 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland

10/08/2021 - 10/12/2021

Immunophenotypic Stability of Minimal Residual Disease (MRD) Assessment in B Lymphoblastic Leukemia / Lymphoma (B-ALL) by Flow Cytometry (FC) 2021 ICCS Annual Clinical Cytometry Meeting and Course Baltimore, Maryland

10/08/2021 - 10/12/2021

Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) as Demonstrated by Improvements in Bone Marrow Function and Clinical Activity in Patients With Myelofibrosis – Preliminary Data. 63rd ASH Annual Meeting Atlanta, Georgia

12/11/2021 - 12/14/2021

Regional

Invited

Prognostic significance of CD200 expression in immunoproliferative and post transplant lymphoproliferative disorders Hematologic Malignancy and Transplantation Research Program, Medical College of Wisconsin Cancer Center Milwaukee, Wisconsin

02/14/2013


Page 24 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Clinicopathologic Analysis of the Impact of CD23 Expression in Hematologic Malignancies Hematologic Malignancy and Transplantation Research Program, Medical College of Wisconsin Cancer Center Milwaukee, Wisconsin

10/10/2013

Flow Cytometric Diagnosis of Mature T-Cell Lymphoproliferations 4th Annual Twin Cities Regional Flow Cytometry Conference Minneapolis, Minnesota

03/23/2019

Visiting Professorship Visiting Professorships Diagnostic and prognostic significance of CD200 expression in plasmacytic neoplasms Department of Pathology and Laboratory Medicine Grand Rounds, University of Wisconsin School of Medicine and Public Health Madison, Wisconsin

01/31/2013

Personalized Medicine in Hematologic Malignancies: The Use of Flow Cytometry in Identifying New Diagnostic and Prognostic Markers in Plasma Cell and Lymphoid Disorders Biochemistry Annual Alumni Seminar, University of Nebraska Lincoln, Nebraska

04/23/2013

Clinical and Pathologic Features of Aggressive B-Cell Lymphomas 2015 IOCN Hematology Workshop Cluj-Napoca, Romania

11/05/2015 - 11/07/2015

Biomarker Discovery in Plasmacytoid Neoplasms and Post-Transplant Lymphoproliferative Disorders Department of Pathology, Microbiology and Immunology Laboratory Medicine Grand Rounds, Vanderbilt University School of Medicine Nashville, Tennessee

11/13/2015

Flow Cytometry Diagnosis of Complex Hematopathology Cases Division of Hematopathology, Mayo Clinic Rochester, Minnesota

06/15/2017

Clinical Practice, Interests, and Accomplishments 1. Clinical education and training of residents, fellows, practicing pathologists, and laboratory professionals: A key clinical interest and practice of mine also includes the clinical education and training of future physicians, pathologists, and laboratory professionals. I have made several key contributions that provide guidance and education on how to practice medicine for our future pathologists and laboratorians. These contributions include co-authorship on a comprehensive textbook on Lymph Node Pathology, serving as Program Director for the Hematopathology fellowship, and as member of chair of several clinical practice and education committees of national and international Pathology organizations, including the Association for Clinical Pathology (ASCP), College of American Pathologists (CAP), Society for Hematopathology (SH), and International Clinical Cytometry Society (ICCS). As chair of ASCP’s Pathologist Recertification Individualize Self-Assessment Examination (PRISE) committee, I have overseen and implemented a highly successful clinical education program that over the last 5 years experienced an average of 580 unique participants for each of the 25-30 annual subspecialty modules published by the committee. In addition to practicing pathologists, over 60% of US Pathology residency programs have subscribed to this program, making it a valuable training tool for residents and program directors. 2. Immunophenotypic characterization of hematologic malignancies for relevant diagnostic and prognostic markers: My personal and professional goals have been and will remain a striving for diagnostic excellence in Hematopathology, and a close involvement in, and creation of an environment of enhanced learning for medical professionals, including pathologists and oncologists. Since my initial appointment at the Medical College of Wisconsin, I was grateful for having the opportunity to support the departmental and institutional goals of patient care and education, particularly in providing a diagnostic service which supported the Division of Hematology and Oncology in providing high-quality patient care. Since I took over as medical director, the MCW Clinical Flow Cytometry laboratory experienced a tremendous growth in testing volume, sustaining an average 10% increase/year. Under my supervision, the laboratory transitioned from 4-color to 8-color flow cytometry testing, which is particularly useful in providing more detailed diagnostic information derived from limited specimens and uses less antibodies, thus contributing to a decrease in operating costs. Our laboratory was the first one in the


Page 25 of 36

RE-AIMS 9/1/2021 9:59:14 AM

state of Wisconsin to offer 8-color flow cytometry testing. We were also following patients treated at a busy bone marrow transplant center, including minimal residual disease analysis for plasma cell myeloma, acute leukemia, and lymphoproliferative disorders, as the first laboratory in the state of Wisconsin to offer these tests. My clinical expertise in flow cytometry and Hematopathology has resulted in several key publications on guiding therapy in patients with T cell lymphoproliferative disorders (Olteanu H, Harrington AM, Hari P, Kroft SH. Imrnunophenotypic Stability of Sezary Cells by Flow Cytometry: Utility of Flow Cytometry in Assessing Response to and Guiding Alemtuzumab Therapy. Am J Clin Pathol. 2012; 137(3):403-411.; Hari P, Raj RV, Olteanu H. Targeting CD38 in Refractory Extranodal Natural Killer Cell-T-Cell Lymphoma. N Engl J Med 2016 Oct 13; 375 (15):1501-1502) and as senior Pathology author for several publications of the Center for International Blood and Bone Marrow Transplant Research (CIBMTR) on the largest North American cohort of patients with aggressive NK cell lymphorpliferative disorders (Hamadani M, Kanate AS, DiGilio A, Ahn KW, Smith SM, Lee JW, Ayala E, Chao N, Hari P, Bolanos-Meade J, Gress R, Smedegaard Anderson N, Chen YB, Farooq U, Schiller G, Yared J, Sureda A, Fenske TS, Olteanu H. Allogeneic Hematopoietic Cell Transplantation for Aggressive NK Cell Leukemia. A Center for International Blood and Marrow Transplant Research Analysis. Biol Blood Marrow Transplant. 2017 May; 23 (5):853-856 Epub 2017 Feb 01; Kanate, A.S., DiGilio, A., Ahn, K.W., Al Malki, M., Jacobsen, E., Steinberg, A., Hamerschlak, N., Kharfan-Dabaja, M., Salit, R., Ball, E., Bashir, Q., Cashen, A., Couriel, D., Diez-Martin, J., Katasanis, E., Linhares, Y., Mori, S., Nash, R., Pawarode, A., Perales, M.A., Phipps, C.D., Richman, C., Savania, B.N., Shapira, M.Y., Stiff, P., Strair, R., Fenske, T.S., Smith, S.M., Sureda, A., Olteanu, H., Hamadani, M.: Allogeneic Hematopoietic Cell Transplantation for Extranodal Natural Killer/T-cell Lymphoma, Nasal Type. A CIBMTR Analysis. Br J Haematol 2017 Aug 2. PMID: 28771676 doi: 10.1111/bjh.14879. [Epub ahead of print]).

Research Interests and Accomplishments 1. Biomarker discovery in hematologic neoplasms: Our group was the first to publish on the clinical and pathologic impact of diagnostic and prognostic markers such as CD23 and CD200 in follicular lymphoma, plasma cell myeloma, and plasma cell dyscrasias. Currently, I am continuing these studies by focusing on post-transplant lymphoproliferative disorders (PTLDs) and the interplay of regulatory T cells (Tregs), CD200 and CD30 expression, and EBV status on clinical outcome. We are employing a combination of tissue microarray immunohistochemistry, in situ hybridization, imaging studies and B-cell receptor gene rearrangement RT-PCR to address the utility of new biomarkers for prognostic and therapeutic purposes. Olteanu, H., Fenske, T.S., Harrington, A.M., Szabo, A., He, P., Kroft, S.H.: CD23 expression in follicular lymphoma: clinicopathologic correlations. Am J Clin Pathol, 135 (1): 46-53, 2011. Buonaccorsi, J.B., Kroft, S.H., Harrington, A.M., VanTuinen, P., Olteanu, H.: Clinicopathologic analysis of the impact of CD23 expression in plasma cell myeloma with t(11;14)(q13;q32). Ann Diagn Pathol, 15 (6): 385-388, 2011. Olteanu, H., Harrington, A.M., Kroft, S.H.: CD200 Expression in Plasma Cells of Non-Myeloma Immunoproliferative Disorders: Clinicopathologic Features and Comparison with Plasma Cell Myeloma. Am J Clin Pathol, 138 (6): 867-876, 2012. Hartley, C., Vaughan, J.W., Jarzembowsi, J., Kroft, S.H, Hosking, P.R., Harrington, A.M., Mackinnon, A.C, Olteanu, H.: CD30 Expression in Monomorphic Post-Transplant Lymphoproliferative Disorder, Diffuse Large B-cell Lymphoma Correlates with Greater Regulatory T-Cell Infiltration. Am J Clin Pathol, 20;148(6):485-493, 2017. 2. Gammaherpesvirus-induced lymphomagenesis in immunocompetent and immune-deficient individuals: I am collaborating with Dr. Vera Tarakanova from the Medical College of Wisconsin on a project which poses a clinically relevant interdisciplinary conundrum at the crossroads of molecularly relevant host factors (IRF-1 expression) and gammaherpervirus-driven lymphomagenesis. Prior to our studies, the role of IRF-1 in the regulation of gammaherpesvirus replication, chronic infection, and pathogenesis was poorly understood. Our group was the first to demonstrate that gammaherpesvirus infection synergizes with IRF-1 deficiency to induce B cell lymphomas. This innovative project is based on our observation that IRF-1 suppresses gammaherpesvirus-driven expansion of germinal center B cells; this is the first time IRF-1 has been implicated in virus-driven B cell differentiation and has resulted in intramural and extramural funding. Successful completion of the proposed studies will establish a novel and tractable animal model of gammaherpesvirus lymphomagenesis. The ultimate, long-term goal of our research is to determine the extent to which IRF-1-regulated gene expression suppresses gammaherpesvirus-induced cancer in humans. Mboko, J.P., Olteanu, H., Ray, A., Darrah, E., Kulinski, J.M., Cui, W., Dittel, B., Gauld, S.B., Tarakanova, V.L.: Tumor suppressor IRF-1 counteracts expansion of germinal centers driven by a cancer-associated gammaherpesvirus. J Virol, 90 (6): 2818-2829, 2015. Darrah, E., Johnson, K.E., Lange, P.T., Olteanu, H., Tarakanova, V.L.: Conserved viral protein kinase selectively promotes irrelevant B cell responses. J Exp Med 2018 (submitted for review) 3. Immunophenotypic characterization of hematologic malignancies for relevant diagnostic and prognostic markers: Our group’s clinical research is focused on the application of specialized ancillary techniques, in particular flow cytometry, to the clinical and pathologic characterization of hematolymphoid malignancies. We were the first to publish on the temporal immunophenotypic changes of neoplastic cells in plasma cell myeloma and T-cell large granular lymphocytic leukemia, and to provide a detailed characterization of normal and aberrant NK cells in the post-transplant setting or in neoplastic conditions: Spears, M.D., Harrington, A.M., Kroft, S.H., Olteanu, H.: Immunophenotypic stability of T-cell large granular lymphocytic leukemia by flow cytometry. Br J Haematol, 151


Page 26 of 36

RE-AIMS 9/1/2021 9:59:14 AM

(1): 97-99, 2010. Olteanu, H., Schur, B.C., Atallah, E., Bredeson, C., Kroft, S.H.: Expression of Natural Killer Receptors in T and NK cells: Comparison of Healthy Individuals, Stem Cell Transplant Patients and Chemotherapy Patients. Leuk Lymphoma 51 (3): 481-487, 2010. Morice, W.G., Jevremovic, D., Olteanu, H., Roden, A., Nowakowski, G., Kroft, S.H., Hanson, C.A., Kurtin, P.J.: Chronic Lymphoproliferative Disorder of Natural Killer Cells: A Distinct Entity with Sub-Types Correlating With Normal Natural Killer Cell Subsets. Leukemia 24 (4): 881-884, 2010. Hari, P., Raj, R., Olteanu, H.: Targeting CD38 in Refractory Natural Killer Cell-T-Cell Lymphoma. New Engl J Med, 375 (15): 1501-1502, 2016.

Research Grants Awarded

Active Grants

Federal Co-Investigator lRF-1: A Brake to Limit Gammaherpesvirus Infection and Pathogenesis .

Funded by NIH. (RO1 CA 203923) 09/2016 - 08/2021

Federal sub award Program Director / Principal Investigator

IRF-1: a brake to limit gammaherpesvirus infection and pathogenesis. Funded by National Cancer Institute. (CA 203923)

12/2017 - 11/2021

Program Director / Principal Investigator

ECOG-ACRIN Operations Center – Clinical Trials - EAA171 BIQSFP Supplement. Funded by National Cancer Institute. (CA 180820)

03/2020 - 02/2022

Completed Grants

Foundation Co-Investigator Role of Tumor Suppressor IRF-1 in Viral Lymphomagenesis. Funded by

Thomas A. and Lorraine M. Rosenberg Award for Translational Cancer Research

05/2016 - 04/2018


Page 27 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Bibliography

Peer-reviewed Articles 1. Olteanu H, Banerjee R. Human methionine synthase reductase, a soluble P450 reductase-like dual

flavoprotein, is sufficient for NADPH-dependent methionine synthase activation J Biol Chem. 2001; 276(38):35558-35563. PMID: 11466310 DOI: 10.1074/jbc.M103707200

2. Olteanu H, Munson T, Banerjee R. Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase. Biochemistry. 2002 Nov 12; 41 (45):13378-85 PMID: 12416982

3. Olteanu H, Banerjee R. Redundancy in the pathway for redox regulation of mammalian methionine synthase: reductive activation by the dual flavoprotein, novel reductase 1. J Biol Chem. 2003 Oct 3; 278 (40):38310-4 Epub 2003 July 18 PMID: 12871938 DOI: 10.1074/jbc.M306282200

4. Olteanu H, Wolthers KR, Munro AW, Scrutton NS, Banerjee R. Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase. Biochemistry. 2004 Feb 24; 43 (7):1988-97 PMID: 14967039 DOI: 10.1021/bi035910i

5. Waly M, Olteanu H, Banerjee R, Choi SW, Mason JB, Parker BS, Sukumar S, Shim S, Sharma A, Benzecry JM, Power-Charnitsky VA, Deth RC. Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Mol Psychiatry. 2004 Apr; 9 (4):358-70 PMID: 14745455 DOI: 10.1038/sj.mp.4001476

6. Leal NA, Olteanu H, Banerjee R, Bobik TA. Human ATP:Cob(I)alamin adenosyltransferase and its interaction with methionine synthase reductase. J Biol Chem. 2004 Nov 12; 279 (46):47536-42 Epub 2004 Aug 30 PMID: 15347655 DOI: 10.1074/jbc.M405449200

7. Olteanu H, Gerber D, Partridge K, Sarode R. Acute hemolytic transfusion reaction secondary to anti-Fy3. Immunohematology. 2005; 21 (2):48-52 PMID: 15981343

8. Zhang W, Braun A, Bauman Z, Olteanu H, Madzelan P, Banerjee R. Expression profiling of homocysteine junction enzymes in the NCI60 panel of human cancer cell lines. Cancer Res. 2005 Feb 15; 65 (4):1554-60 PMID: 15735045 DOI: 10.1158/0008-5472.CAN-04-1554

9. Olteanu H, Xu Y. The use of flow cytometry in diagnosis of paroxysmal nocturnal hemoglobinuria. Lab Med. 2006; 37(8):2-6.

10. Olteanu H, Karandikar NJ, McKenna RW, Xu Y. Differential usefulness of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and bone marrow. Am J Clin Pathol. 2006 Nov; 126 (5):781-8 PMID: 17050075 DOI: 10.1309/AT9Y-6WR0-3PX1-K228

11. Dyszkiewicz-Korpanty A, Olteanu H, Frenkel EP, Sarode R. Clopidogrel anti-platelet effect: an evaluation by optical aggregometry, impedance aggregometry, and the platelet function analyzer (PFA-100). Platelets. 2007 Nov; 18 (7):491-6 PMID: 17852774 DOI: 10.1080/09537100701280654

12. Olteanu H, Wang HY, Chen W, McKenna RW, Karandikar NJ. Immunophenotypic studies of monoclonal gammopathy of undetermined significance. BMC Clin Pathol. 2008 Nov 28; 8:13 PMID: 19040735 PMCID: 2606678 DOI: 10.1186/1472-6890-8-13

13. Olteanu H, Downes KA, Patel J, Praprotnik D, Sarode R. Warfarin does not interfere with lupus anticoagulant detection by dilute Russell's viper venom time. Clin Lab. 2009; 55 (3-4):138-42 PMID: 19462936

14. Olteanu H, Harrington A, Kroft SH. Sperm in peritoneal fluid from a man with ascites: a case report. Cases J. 2009 Nov 12; 2:192 PMID: 19946502 PMCID: 2783147 DOI: 10.1186/1757-1626-2-192

15. Parker SM, Olteanu H, VanTuinen P, Lawton CA, Schultz CJ, Christians KK, Fenske TS. Follicular lymphoma transformation to dual translocated Burkitt-like lymphoma: improved disease control associated with radiation therapy. Int J Hematol. 2009 Dec; 90 (5):616-622 Epub 2009 Nov 25 PMID: 19937165 DOI: 10.1007/s12185-009-0444-9

16. Olteanu H, Karandikar NJ, Eshoa C, Kroft SH. Laboratory Findings in CD4(+) Large Granular Lymphocytoses. Int J Lab Hematol. 2010; 32(1 Pt 1):e9-e16. PMID: 20089001

17. Olteanu H, Schur BC, Bredeson C, Atallah E, Kroft SH. Expression of natural killer receptors in T- and NK-cells: comparison of healthy individuals, patients with prior stem cell transplant, and patients undergoing chemotherapy. Leuk Lymphoma. 2010 Mar; 51 (3):481-7 Epub 2010 Feb 08 PMID: 20141431 DOI: 10.3109/10428190903552120

18. Harrington AM, Currey A, Olteanu H, Kroft SH. Persistent localized bone marrow aplasia after radiotherapy with preserved peripheral counts: a study of 8 cases. Ann Diagn Pathol. 2010 Jun; 14 (3):168-72 PMID: 20471561 DOI: 10.1016/j.anndiagpath.2010.02.006


Page 28 of 36

RE-AIMS 9/1/2021 9:59:14 AM

19. * Plaza JA, Ortega P, Lynott J, Mullane M, Kroft S, Olteanu H. CD8-positive primary cutaneous anaplastic large T-cell lymphoma (PCALCL): case report and review of this unusual variant of PCALCL. Am J Dermatopathol. 2010 Jul; 32 (5):489-91 PMID: 20442639 DOI: 10.1097/DAD.0b013e3181c57ec2

20. Harrington A, Olteanu H, Kroft S. The specificity of immunophenotypic alterations in blasts in nonacute myeloid disorders. Am J Clin Pathol. 2010 Nov; 134 (5):749-61 PMID: 20959658 DOI: 10.1309/AJCPFNF5MN1GDWKU

21. Olteanu H, Harrington AM, Hari P, Kroft SH. CD200 expression in plasma cell myeloma Br J Haematol. 2011; 153(3):408-411. PMID: 21275968

22. Olteanu H, Fenske TS, Harrington AM, Szabo A, He P, Kroft SH. CD23 expression in follicular lymphoma: clinicopathologic correlations. Am J Clin Pathol. 2011 Jan; 135 (1):46-53 PMID: 21173123 DOI: 10.1309/AJCP27YWLIQRAJPW

23. Torgerson S, Olteanu H, Tinguely M, Fenske TS. Central nervous system Hodgkin lymphoma: case report and review of the literature. J Neurooncol. 2011 Apr; 102 (2):329-34 Epub 2010 July 31 PMID: 20676729 DOI: 10.1007/s11060-010-0320-8

24. Olteanu H. Case Study Interpretation--Houston: Case 2. Classical Hodgkin lymphoma. Cytometry B Clin Cytom. 2011 Jul-Aug; 80 (4):258-60 Epub 2011 June 02 PMID: 21638769 DOI: 10.1002/cyto.b.20598

25. Spears MD, Olteanu H, Kroft SH, Harrington AM. The immunophenotypic stability of plasma cell myeloma by flow cytometry. Int J Lab Hematol. 2011 Oct; 33 (5):483-91 Epub 2011 Apr 07 PMID: 21470371 DOI: 10.1111/j.1751-553X.2011.01317.x

26. * Buonaccorsi JN, Kroft SH, Harrington AM, VanTuinen P, Olteanu H. Clinicopathologic analysis of the impact of CD23 expression in plasma cell myeloma with t(11;14)(q13;q32). Ann Diagn Pathol. 2011 Dec; 15 (6):385-8 Epub 2011 July 02 PMID: 21724429 DOI: 10.1016/j.anndiagpath.2011.04.004

27. * Horna P, Olteanu H, Kroft SH, Harrington AM. Flow cytometric analysis of surface light chain expression patterns in B-cell lymphomas using monoclonal and polyclonal antibodies. Am J Clin Pathol. 2011 Dec; 136 (6):954-9 PMID: 22095382 DOI: 10.1309/AJCP3C2QZZBPTMLB

28. Olteanu H, Schur BC, Harrington AM, Kroft SH. Time and temperature stability of T-cell subsets evaluated by a dual-platform method. Am J Blood Res. 2012; 2 (2):128-35 Epub 2012 May 25 PMID: 22762032 PMCID: 3384401

29. Olteanu H, Harrington AM, George B, Hari PN, Bredeson C, Kroft SH. High prevalence of Dapsone-induced oxidant hemolysis in North American SCT recipients without glucose-6-phosphate-dehydrogenase deficiency. Bone Marrow Transplant. 2012 Mar; 47 (3):399-403 Epub 2011 Apr 11 PMID: 21478917 DOI: 10.1038/bmt.2011.83

30. * Vaughan J, Harrington AM, Hari PN, Kroft SH, Olteanu H. Immunophenotypic stability of Sezary cells by flow cytometry: usefulness of flow cytometry in assessing response to and guiding alemtuzumab therapy. Am J Clin Pathol. 2012 Mar; 137 (3):403-11 PMID: 22338052 DOI: 10.1309/AJCP7QHH5XASTJPL

31. Harrington AM, Olteanu H, Kroft SH. A dissection of the CD45/side scatter "blast gate". Am J Clin Pathol. 2012 May; 137 (5):800-4 PMID: 22523220 DOI: 10.1309/AJCPN4G1IZPABRLH

32. Olteanu H, Harrington AM, Kroft SH. CD200 expression in plasma cells of nonmyeloma immunoproliferative disorders: clinicopathologic features and comparison with plasma cell myeloma. Am J Clin Pathol. 2012 Dec; 138 (6):867-76 PMID: 23161721 DOI: 10.1309/AJCP3TQR1TFHHGAS

33. Cogbill CH, Spears MD, Vantuinen P, Harrington AM, Olteanu H, Kroft SH. Morphologic and cytogenetic variables affect the flow cytometric recovery of plasma cell myeloma cells in bone marrow aspirates. Int J Lab Hematol. 2015 Dec; 37 (6):797-808 Epub 2015 July 30 PMID: 26224420 DOI: 10.1111/ijlh.12411

34. Mboko WP, Olteanu H, Ray A, Xin G, Darrah EJ, Kumar SN, Kulinski JM, Cui W, Dittel BN, Gauld SB, Tarakanova VL. Tumor Suppressor Interferon-Regulatory Factor 1 Counteracts the Germinal Center Reaction Driven by a Cancer-Associated Gammaherpesvirus. J Virol. 2015 Dec 30; 90 (6):2818-29 PMID: 26719266 PMCID: 4810652 DOI: 10.1128/JVI.02774-15

35. Abidi MZ, Haque J, Varma P, Olteanu H, Guru Murthy GS, Dhakal B, Hari P. Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib. Case Rep Hematol. 2016; 2016:2389038 Epub 2016 Oct 23 PMID: 27843657 PMCID: 5097796 DOI: 10.1155/2016/2389038

36. Olteanu H. Role of Flow Cytometry in the Diagnosis and Prognosis of Plasma Cell Myeloma. Surg Pathol Clin. 2016 Mar; 9 (1):101-16 PMID: 26940271 DOI: 10.1016/j.path.2015.09.009

37. * Li H, Hasserjian RP, Kroft SH, Harrington AM, Wheaton SE, Pildain A, Ewalt MD, Gratzinger D, Hosking P, Olteanu H. Pure Erythroid Leukemia and Erythroblastic Sarcoma Evolving From Chronic Myeloid Neoplasms. Am J Clin Pathol. 2016 Apr; 145 (4):538-51 Epub 2016 Apr 22 PMID: 27124944 DOI: 10.1093/ajcp/aqw033

38. Harrington AM, Schelling LA, Ordobazari A, Olteanu H, Hosking PR, Kroft SH. Immunophenotypes of Chronic Myelomonocytic Leukemia (CMML) Subtypes by Flow Cytometry: A Comparison of CMML-1 vs CMML-2,


Page 29 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Myeloproliferative vs Dysplastic, De Novo vs Therapy-Related, and CMML-Specific Cytogenetic Risk Subtypes. Am J Clin Pathol. 2016 Aug; 146 (2):170-81 Epub 2016 July 13 PMID: 27413139 DOI: 10.1093/ajcp/aqw084

39. Chang JC, Harrington AM, Olteanu H, VanTuinen P, Kroft SH. Proliferation centers in bone marrows involved by chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic analysis. Ann Diagn Pathol. 2016 Dec; 25:15-19 Epub 2016 Aug 18 PMID: 27806839 DOI: 10.1016/j.anndiagpath.2016.07.011

40. * Epperla N, Olteanu H, Hamadani M. Think outside the box: Acanthamoeba encephalitis following autologous haematopoietic stem cell transplantation. Br J Haematol. 2016 Dec; 175 (5):758 Epub 2016 Sept 21 PMID: 27650173 DOI: 10.1111/bjh.14329

41. * Popa G, Blag C, Olteanu H. Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient. Pediatr Dev Pathol. 2017 Jan-Feb; 20 (1):58-62 PMID: 28276292 DOI: 10.1177/1093526616671047

42. * Rowan DJ, Logunova V, van Tuinen P, Olteanu H, Peterson JF. Circulating Breast Carcinoma Cells Mimicking Therapy-Related Acute Myeloid Leukemia. Int J Surg Pathol. 2017 Feb; 25 (1):87-93 Epub 2016 Aug 20 PMID: 27543510 DOI: 10.1177/1066896916664986

43. Hamadani M, Kanate AS, DiGilio A, Ahn KW, Smith SM, Lee JW, Ayala E, Chao N, Hari P, Bolanos-Meade J, Gress R, Smedegaard Anderson N, Chen YB, Farooq U, Schiller G, Yared J, Sureda A, Fenske TS, Olteanu H. Allogeneic Hematopoietic Cell Transplantation for Aggressive NK Cell Leukemia. A Center for International Blood and Marrow Transplant Research Analysis. Biol Blood Marrow Transplant. 2017 May; 23 (5):853-856 Epub 2017 Feb 01 PMID: 28161608 PMCID: 5410937 DOI: 10.1016/j.bbmt.2017.01.082

44. * Batdorf BH, Kroft SH, Hosking PR, Harrington AM, Mackinnon AC, Olteanu H. Evaluation of CD43 expression in non-hematopoietic malignancies. Ann Diagn Pathol. 2017 Aug; 29:23-27 Epub 2017 Apr 26 PMID: 28807337 DOI: 10.1016/j.anndiagpath.2017.04.010

45. * Hartley C, Vaughan JW, Jarzembowski J, Kroft SH, Hosking P, Harrington AM, Olteanu H. CD30 Expression in Monomorphic Posttransplant Lymphoproliferative Disorder, Diffuse Large B-Cell Lymphoma Correlates With Greater Regulatory T-Cell Infiltration. Am J Clin Pathol. 2017 Nov 20; 148 (6):485-493 PMID: 29126177 DOI: 10.1093/ajcp/aqx097

46. Kharfan-Dabaja MA, Al Malki MM, Deotare U, Raj RV, El-Jurdi N, Majhail N, Cherry MA, Bashir Q, Darrah J, Nishihori T, Sibai H, Hamadani M, de Lima M, Gerds AT, Selby G, Qazilbash MH, Forman SJ, Ayala E, Lipton JH, Hari PN, Muzzafar T, Zhang L, Olteanu H, Perkins J, Sokol L, Kumar A, Ahmed S. Haematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a North American multicentre collaborative study. Br J Haematol. 2017 Dec; 179 (5):781-789 Epub 2017 Oct 04 PMID: 28980314 DOI: 10.1111/bjh.14954

47. Sinkoff J, Olteanu H, Peterson JF, Shah NN. Leukemic phase and CSF involvement of diffuse large B-cell lymphoma with a complex karyotype including a TP53 deletion. Clin Case Rep. 2018 Jan; 6 (1):235-237 Epub 2017 Dec 05 PMID: 29375876 PMCID: 5771872 DOI: 10.1002/ccr3.1250

48. Kharfan-Dabaja MA, Raj R, Nikolaenko L, Ahmed S, Reddy N, Nathan S, Cherry M, El-Jurdi N, Obiozor C, Fenske TS, Song J, Muzzafar T, Ayala E, Savani B, Khawandanah M, Caimi PF, Hamadani M, Forman SJ, Hussaini M, de Lima M, Olteanu H, Shah B, Chavez JC, Al Malki M, Kumar A, Ganguly S. Efficacy of High-Dose Therapy and Autologous Hematopoietic Cell Transplantation in Gray Zone Lymphoma: A US Multicenter Collaborative Study. Biol Blood Marrow Transplant. 2018 Mar; 24 (3):486-493 Epub 2017 Dec 07 PMID: 29225164 DOI: 10.1016/j.bbmt.2017.11.033

49. * Abdelkader A, Olteanu H. Clinical and Pathologic Features of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Pediatric Patient Arch Clin Cases. 2018; 5(2):47-52. DOI: http://dx.doi.org/10.22551/2018.19.0502.10127

50. Merzianu M, Groman A, Hutson A, Cotta C, Brynes RK, Orazi A, Reddy V, Teruya-Feldstein J, Amre R, Balasubramanian M, Brandao G, Cherian S, Courville E, Czuchlewski D, Fan G, Grier D, Hoehn D, Inamdar KV, Juskevicius R, Kaur P, Lazarchick J, Lewis MR, Miles RR, Myers JB, Nasr MR, Qureishi HN, Olteanu H, Robu VG, Salaru G, Vajpayee N, Vos J, Zhang L, Zhang S, Aye L, Brega E, Coad JE, Grantham J, Ivelja S, McKenna R, Sultan K, Wilding G, Hutchison R, Peterson L, Cheney RT. Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada: A Multicenter Study. Am J Clin Pathol. 2018 Oct 1; 150 (5):393-405 PMID: 30052721 PMCID: 6166687 DOI: 10.1093/ajcp/aqy066

51. Ronen S, Kroft SH, Olteanu H, Hosking PR, Harrington AM. Carcinocythemia: A rare entity becoming more common? A 3-year, single institution series of seven cases and literature review. Int J Lab Hematol. 2019 Feb; 41 (1):69-79 Epub 2018 Sept 14 PMID: 30216684 DOI: 10.1111/ijlh.12924

52. Shah NN, Szabo A, Saba R, Strelec L, Kodali D, Vaughn JL, Esan O, Yang DT, Mato AR, Kanate AS, Olteanu H, Hamadani M, Fenske TS, Kenkre VP, Svoboda J, Cashen AF, Epperla N. Multicenter Analysis of


Page 30 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Advanced Stage Grade 3A Follicular Lymphoma Outcomes by Frontline Treatment Regimen. Clin Lymphoma Myeloma Leuk. 2019 Feb; 19 (2):95-102 Epub 2018 Nov 12 PMID: 30581160 DOI: 10.1016/j.clml.2018.11.010

53. Jevremovic D, Olteanu H. Flow Cytometry Applications in the Diagnosis of T/NK-Cell Lymphoproliferative Disorders. Cytometry B Clin Cytom. 2019 Mar; 96 (2):99-115 Epub 2019 Feb 06 PMID: 30729667 DOI: 10.1002/cyto.b.21768

54. Darrah EJ, Jondle CN, Johnson KE, Xin G, Lange PT, Cui W, Olteanu H, Tarakanova VL. Conserved Gammaherpesvirus Protein Kinase Selectively Promotes Irrelevant B Cell Responses. J Virol. 2019 Apr 15; 93 (8) Epub 2019 Apr 03 PMID: 30728267 PMCID: 6450124 DOI: 10.1128/JVI.01760-18

55. Shi M, Jevremovic D, Otteson GE, Timm MM, Olteanu H, Horna P. Single Antibody Detection of T-Cell Receptor alphabeta Clonality by Flow Cytometry Rapidly Identifies Mature T-Cell Neoplasms and Monotypic Small CD8-Positive Subsets of Uncertain Significance. Cytometry B Clin Cytom. 2020 Jan; 98 (1):99-107 Epub 2019 Apr 11 PMID: 30972977 DOI: 10.1002/cyto.b.21782

56. Shi M, Rech KL, Otteson GE, Horna P, Olteanu H, Pardanani A, Chen D, Jevremovic D. Prevalence and spectrum of T-cell lymphoproliferative disorders in patients with Hypereosinophilia: A reference laboratory experience. Ann Diagn Pathol. 2020 Feb; 44:151412 Epub 2019 Oct 18 PMID: 31778950 DOI: 10.1016/j.anndiagpath.2019.151412

57. Polonis K, Schultz MJ, Olteanu H, Smadbeck JB, Johnson SH, Vasmatzis G, Xu X, Greipp PT, Ketterling RP, Hoppman NL, Baughn LB, Peterson JF. Detection of cryptic CCND1 rearrangements in mantle cell lymphoma by next generation sequencing. Ann Diagn Pathol. 2020 Jun; 46:151533 Epub 2020 May 06 PMID: 32408254 DOI: 10.1016/j.anndiagpath.2020.151533

58. * Vaughan JW, Shi M, Horna P, Olteanu H. Increased CD200 expression in post-transplant lymphoproliferative disorders correlates with an increased frequency of FoxP3(+) regulatory T cells. Ann Diagn Pathol. 2020 Oct; 48:151585 Epub 2020 Aug 14 PMID: 32829067 DOI: 10.1016/j.anndiagpath.2020.151585

59. Shi M, Olteanu H, Jevremovic D, He R, Viswanatha D, Corley H, Horna P. T-cell clones of uncertain significance are highly prevalent and show close resemblance to T-cell large granular lymphocytic leukemia. Implications for laboratory diagnostics. Mod Pathol. 2020 Oct; 33 (10):2046-2057 Epub 2020 May 13 PMID: 32404954 DOI: 10.1038/s41379-020-0568-2

60. Shi M, Nguyen P, Timm MM, Otteson GE, Horna P, Olteanu H, Jevremovic D. Cytoplasmic Expression of CD3epsilon Heterodimers by Flow Cytometry Rapidly Distinguishes Between Mature T-Cell and Natural Killer-Cell Neoplasms. Am J Clin Pathol. 2020 Oct 13; 154 (5):683-691 PMID: 32589191 DOI: 10.1093/ajcp/aqaa086

61. Sheets JW, Eulitt P, He R, Olteanu H, Coombs CC, Foster MC, Montgomery ND, Zeidner JF. Philadelphia Chromosome-positive Acute Myeloid Leukemia With e1a3 BCR-ABL1 Fusion Transcript. Hemasphere. 2020 Dec; 4 (6):e484 Epub 2020 Oct 14 PMID: 33134868 PMCID: 7566865 DOI: 10.1097/HS9.0000000000000484

62. Horna P, Shi M, Olteanu H, Johansson U. Emerging Role of T-cell Receptor Constant beta Chain-1 (TRBC1) Expression in the Flow Cytometric Diagnosis of T-cell Malignancies. Int J Mol Sci. 2021 Feb 12; 22 (4) PMID: 33673033 PMCID: 7918842 DOI: 10.3390/ijms22041817

63. Horna P, Shi M, Jevremovic D, Craig FE, Comfere NI, Olteanu H. Utility of TRBC1 Expression in the Diagnosis of Peripheral Blood Involvement by Cutaneous T-Cell Lymphoma. J Invest Dermatol. 2021 Apr; 141 (4):821-829.e2 Epub 2020 Oct 10 PMID: 33049270 DOI: 10.1016/j.jid.2020.09.011

64. Li M, Binder M, Lasho T, Ferrer A, Gangat N, Al-Kali A, Mangaonkar A, Elliott M, Litzow M, Hogan W, Pardanani A, Wolanskyj-Spinner A, Howard M, King RL, Shah M, Alkhateeb H, Begna K, Tefferi A, Finke C, Oliveira J, Ketterling R, Olteanu H, Patnaik MM. Clinical, molecular, and prognostic comparisons between CCUS and lower-risk MDS: a study of 187 molecularly annotated patients. Blood Adv. 2021 Apr 27; 5 (8):2272-2278 PMID: 33904893 PMCID: 8095155 DOI: 10.1182/bloodadvances.2020003976

65. Berg H, Otteson GE, Corley H, Shi M, Horna P, Jevremovic D, Olteanu H. Flow cytometric evaluation of TRBC1 expression in tissue specimens and body fluids is a novel and specific method for assessment of T-cell clonality and diagnosis of T-cell neoplasms. Cytometry B Clin Cytom. 2021 May; 100 (3):361-369 Epub 2020 Apr 25 PMID: 32333725 DOI: 10.1002/cyto.b.21881

66. Zheng G, He R, Reichard KK, Peterson JF, Olteanu H, Oliveira JL, Rangan A, Chen D, Shi M. Genetic and Clinical Studies of Patients With Increased Multinucleated Megakaryocytes in Bone Marrow as an Isolated Finding: A Diagnostic Pitfall for Myelodysplastic Syndrome. Am J Surg Pathol. 2021 May 13 [Epub ahead of print] PMID: 33999554 DOI: 10.1097/PAS.0000000000001732

67. Horna P, Olteanu H, Jevremovic D, Otteson GE, Corley H, Ding W, Parikh SA, Shah MV, Morice WG, Shi M. Single-Antibody Evaluation of T-Cell Receptor beta Constant Chain Monotypia by Flow Cytometry Facilitates the Diagnosis of T-Cell Large Granular Lymphocytic Leukemia. Am J Clin Pathol. 2021 Jun 17; 156 (1):139-148 PMID: 33438036 DOI: 10.1093/ajcp/aqaa214


Page 31 of 36

RE-AIMS 9/1/2021 9:59:14 AM

68. Horna P, Otteson GE, Shi M, Jevremovic D, Yuan J, Olteanu H. Flow Cytometric Evaluation of Surface and Cytoplasmic TRBC1 Expression in the Differential Diagnosis of Immature T-Cell Proliferations. Am J Clin Pathol. 2021 Jul 24 Epub 2021 July 24 PMID: 34302330 DOI: 10.1093/ajcp/aqab098

69. Rozenova KA, Jevremovic D, Reichard KK, Nguyen P, Otteson GE, Timm MM, Horna P, Olteanu H, Shi M. CD2 and CD7 are sensitive flow cytometry screening markers for T-lineage acute leukemia(s): a study of 465 acute leukemia cases. Hum Pathol. 2021 Aug; 114:66-73 Epub 2021 May 18 PMID: 34019867 DOI: 10.1016/j.humpath.2021.05.007

70. Guenzel AJ, Smadbeck JB, Golden CL, Williamson CM, Benevides Demasi JC, Vasmatzis G, Pearce KE, Olteanu H, Xu X, Hoppman NL, Greipp PT, Baughn LB, Ketterling RP, Peterson JF. Clinical utility of next generation sequencing to detect IGH/IL3 rearrangements [t(5;14)(q31.1;q32.1)] in B-lymphoblastic leukemia/lymphoma. Ann Diagn Pathol. 2021 Aug; 53:151761 Epub 2021 May 10 PMID: 33991782 DOI: 10.1016/j.anndiagpath.2021.151761

71. Martin ES, Ferrer A, Mangaonkar AA, Khan SP, Kohorst MA, Joshi AY, Hogan WJ, Olteanu H, Moyer AM, Al-Kali A, Tefferi A, Chen D, Wudhikarn K, Go R, Viswanatha D, He R, Ketterling R, Nguyen PL, Oliveira JL, Gangat N, Lasho T, Patnaik MM. Spectrum of hematological malignancies, clonal evolution and outcomes in 144 Mayo Clinic patients with germline predisposition syndromes. Am J Hematol. 2021 Aug 14 [Epub ahead of print] PMID: 34390506 DOI: 10.1002/ajh.26321

Non-Peer-reviewed Articles 1. Olteanu H, Gander RM, Southern PM. West Nile Virus Serology Testing The Southwestern Lab Bulletin. 2005;

10(9):1-2.

Books 1. Olteanu H, Harrington AM, Kroft SH. Lymph Nodes - Demos Surgical Pathology Guides New York, NY:

Demos Medical Publishing; 2013.245p.

Book Chapters 1. Olteanu H, Banerjee R. Cobalamin-dependent remethylation. In: Homocysteine in Health and Disease.

Cambridge University Press; 2001. p. 135-144. 2. Olteanu H, Banerjee R. Biochemical studies of human methionine synthase reductase. In: Chemistry and

Biochemistry of Pteridines and Folates. Kluwer Academic Publishers; 2002. p. 537-542. 3. Olteanu H. Histiocytic and Dendritic Cell Neoplasms. In: Lymph Nodes - Demos Surgical Pathology Guides.

New York, NY: Demos Medical Publishing; 2013. p. 201-12. 4. Olteanu H. Lymph Node Inclusions. In: Lymph Nodes - Demos Surgical Pathology Guides. New York, NY:

Demos Medical Publishing; 2013. p. 71-6. 5. Olteanu H. Lymphadenopathies Associated With Systemic Disorders. In: Lymph Nodes - Demos Surgical

Pathology Guides. New York, NY: Demos Medical Publishing; 2013. p. 45-70. 6. Olteanu H. Mature B-cell Neoplasms. In: Lymph Nodes - Demos Surgical Pathology Guides. New York, NY:

Demos Medical Publishing; 2013. p. 99-142. 7. Olteanu H. Reactive Lymphadenopathies. In: Olteanu, H, Harrington AM, Kroft SH, editor(s). Lymph Nodes -

Demos Surgical Pathology Guides. 2013. p. 33-44. 8. Olteanu H. Spindle Cell Neoplasms of Lymph Nodes. In: Lymph Nodes - Demos Surgical Pathology Guides.

New York, NY: Demos Medical Publishing; 2013. p. 77-82. 9. Olteanu H. Vascular Lymphadenopathies and Neoplsms of Lymph Nodes. In: Lymph Nodes - Demos Surgical

Pathology Guides. New York, NY: Demos Medical Publishing; 2013. p. 83-92. 10. Olteanu H, Allen TC, Suster S. B-cell lymphoma, Mediastinal, Diffuse and Large. In: Pathology of the Pleura

and Mediastinum (Encyclopedia of Pathology). 2018. p. 33-39. 11. Olteanu H, Allen TC, Suster S. Castleman disease, Mediastinal. In: Pathology of the Pleura and Mediastinum

(Encyclopedia of Pathology). 2018. p. 47-55. 12. Olteanu H, Allen TC, Suster S. Hodgkin lymphoma, Mediastinal. In: Pathology of the Pleura and Mediastinum

(Encyclopedia of Pathology). 2018. p. 160-169. 13. Olteanu H, Molina T, Fend F. Lymphoblastic Lymphoma/Leukemia, Mediastinal. In: Hematopathology

(Encyclopedia of Pathology). 2018. 14. Olteanu H, Allen TC, Suster S. Mediastinal Anaplastic Large Cell Lymphoma. In: Pathology of the Pleura and

Mediastinum (Encyclopedia of Pathology). 2018. p. 200-210.


Page 32 of 36

RE-AIMS 9/1/2021 9:59:14 AM

15. Olteanu H, Allen TC, Suster S. Mediastinal Mucosa-Associated Lymphoid Tissue Lymphoma. In: Pathology of the Pleura and Mediastinum (Encyclopedia of Pathology). 2018. p. 256-261.

16. Olteanu H, Allen TC, Suster S. Pleomorphic Lymphoma, Mediastinal. In: Pathology of the Pleura and Mediastinum (Encyclopedia of Pathology). 2018. p. 303-307.

17. Olteanu, H.. Lymphoblastic Leukemia/Lymphoma. In: Molina, T.J., editor(s). Hematopathology (Encyclopedia of Pathology). Springer, Cham; 2019.

Audio/Video/CD-ROM/etc. 1. Olteanu H. Flow Cytometric Evaluation of Natural Killer Cell-Associated Receptors (NKRs) International

Clinical Cytometry Society Continuing Education Program. Peer-reviewed continuing education and assessment program. September 2013;1-49.

2. * Li H, Olteanu H. Pure Erythroid Leukemia Evolving from Chronic Myeloproliferative Neoplasm Society for Hematopathology Case of the Quarter. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. September 2014;

3. * Schelling L, Olteanu H. Peripheral T-cell Lymphoma, Not Otherwise Specified with Germinal Center Phenotype Society for Hematopathology Case of the Quarter. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. May 2015;1-15.

4. Bradley K, Olteanu H. Dapsone-Associated Oxidant Hemolysis College of American Pathologists HE-B 2016 Proficiency Testing Program. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. April 2016;1-19.

5. Olteanu H. Acute Myeloid Leukemia College of American Pathologists VPBS-B 2017 Proficiency Testing Program. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. April 2017;

6. Olteanu H, Fuda F, Montgomery R, Bass J, Pillai V. Flow Cytometric Applications in the Diagnosis of Acute Myeloid Leukemia International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. April 2017;1-24.

7. Olteanu H. High-grade B-cell lymphoma, with MYC and BCL-2 or BCL-6 rearrangements College of American Pathologists HPATH-A 2017 Program. Peer-reviewed continuing education and assessment program. A combination virtual slide/image-based assessment program that undergoes extensive peer review and quality checks to provide its subscribers with top quality material for ongoing medical education. April 2017;1-28.

8. * Fuda F, Shaver A, League SC, Montgomery R, Bass J, Olteanu H. Early T-Cell Precursor Acute Lymphoblastic Leukemia International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. October 2017;1-26.

9. Olteanu H, Fuda F, Shaver A, League SC, Montgomery R, Bass J. Angioimmunoblastic T-Cell Lymphoma International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. December 2017;1-26.

10. League SC, Montgomery R, Bass J, Fuda F, Shaver A, Olteanu H. Quantitation Methods by Flow Cytometry International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. May 2018;1-10.

11. Olteanu H, Fuda F, Shaver A, League SC, Montgomery R, Bass J. Gating / Analytic Strategies for Diagnostic Flow Cytometry in Patients with Hematologic Malignancies Treated with Monoclonal Antibodies International Clinical Cytometry Society e-Learning Continuing Education Program. Peer-reviewed continuing education and assessment program. September 2018;1-24.

Abstracts 1. Zhang W, Braun A, Bauman Z, Olteanu H, Banerjee R. Profiling four homocysteine-related enzymes in the

NCI60 human cancer cell lines. Molecular & Cellular Proteomics. 2004; 3(10):S194. 2. Olteanu H, Karandikar NJ, McKenna RW, Xu Y. Differential utility of various markers in the flow cytometric

detection of paroxysmal nocturnal hemoglobinuria (PNH) in blood and marrow. Modern Pathology. 2006; 19:240A-241A.


Page 33 of 36

RE-AIMS 9/1/2021 9:59:14 AM

3. Olteanu H, Wang H, Chen W, McKenna RW, Karandikar NJ. Immunophenotypic identification of high-risk monoclonal gammopathy of undetermined significance. Laboratory Investigation. 2007; 87:255A.

4. Olteanu H, Karandikar NJ, Kroft SH. Clinical and laboratory findings in CD4(+) large granular lymphocyte leukemia. Laboratory Investigation. 2008; 88:268A.

5. * Walters MP, Olteanu H, VanTuinen P, Kroft SH. CD23 Expression in Plasma Cell Myeloma Is Specific for Abnormalities of Chromosome 11, and Is Associated with Primary Plasma Cell Leukemia in This Cytogenetic Sub-Group. Modern Pathology. 2009; 22:289A.

6. Olteanu H, Hari P, Schur BC, Kroft SH. Expression of Natural Killer Receptors in T Lymphocytes and NK Cells Post Stem Cell Transplantation. Modern Pathology. 2009; 22:385A-386A.

7. Harrington AM, Olteanu H, Kroft SH. The Specificity of Immunophenotypic Alterations in Blasts in Non-Acute Myeloid Disorders. Modern Pathology. 2009; 22:265A.

8. Harrington AM, Currey AD, Olteanu H, Kroft SH. Persistent Localized Bone Marrow Aplasia Following Radiotherapy With Preserved Peripheral Counts: A Study of Seven Cases. American Journal of Clinical Pathology. 2009; 132(4):631.

9. Olteanu H, Harrington A, George B, Bredeson C, Hari PN, Kroft SH. High Prevalence of Dapsone-Induced Oxidant Hemolysis in North American Stem Cell Transplant Recipients without Glucose-6-Phosphate-Dehydrogenase Deficiency. Blood. 2009; 114(22):1285.

10. Harrington AM, Olteanu H, Kroft SH. A Dissection of the CD45/Side Scatter (SS) Blast Gate in Non-Acute Myeloid Disorders and Non-Neoplastic Bone Marrows. Modern Pathology. 2010; 23:301A.

11. Olteanu H, Harrington AM, Kroft SH. CD23(+) Follicular Lymphoma: Immunophenotypic and Clinical Features. Modern Pathology. 2010; 23:315A.

12. * Spears MD, Olteanu H, Kroft SH, Harrington AM. Immunophenotypic Stability in Plasma Cell Myeloma by Flow Cytometry. Modern Pathology. 2010; 23:323A.

13. * Spears MD, Harrington AM, Kroft SH, Olteanu H. Immunophenotypic Stability of T-Cell Large Granular Lymphocytic Leukemia and Chronic Lymphoproliferative Disorders of NK Cells by Flow Cytometry. Modern Pathology. 2010; 23:323A.

14. Harrington AM, Olteanu H, Kroft SH. Incidental, Immunophenotypically Aberrant Cytotoxic T-Cell Clones in Patients with Other Hematologic Malignancies. Modern Pathology. 2010; 23:301A.

15. Vaughan J, Olteanu H, Wimpee B, Kroft SH, Jarzembowski JA. The Regulatory T-Lymphocyte Content of Post-Transplant Lymphoproliferative Disorders. Modern Pathology. 2010; 23:326A.

16. Olteanu H, Harrington AM, Kroft SH. The Role of Flow Cytometry in the Diagnosis of Intraocular Lymphoma. Modern Pathology. 2010; 23:383A.

17. Olteanu H, Schur CB, Harrington AM, Kroft SH. Time and Temperature Stability of T-Cell Subsets. Modern Pathology. 2010; 23:436A-437A.

18. Cogbill CH, Spears MD, Harrington AM, Olteanu H, Kroft SH. Analysis of Variables Affecting the Flow Cytometric Recovery of Plasma Cell Myeloma Cells in Bone Marrow Aspirates. Modern Pathology. 2011; 24:291A.

19. Olteanu H, Harrington AM, Kroft SH. CD200 Expression in Plasma Cell Myeloma. Modern Pathology. 2011; 24:312A-313A.

20. Rathke SK, Olteanu H, Kroft SH, Harrington AM. CD45 Expression in Plasma Cell Myeloma: Comparison of Flow Cytometry and Immunohistochemistry and Relationship to Prognostic Factors. Modern Pathology. 2011; 24:317A.

21. * Buonaccorsi JN, Kroft SH, Harrington A, VanTuinen P, Olteanu H. Clinicopathologic Analysis of the Impact of CD23 Expression in Plasma Cell Myeloma with t(11;14)(q13;q32). Modern Pathology. 2011; 24:288A.

22. * Horna P, Olteanu H, Kroft S, Harrington A. Flow Cytometric Analysis of Light Chain Expression Patterns in B-cell Lymphomas Using Monoclonal and Polyclonal Antibodies. Mod Pathol. 02/01/2011; 24(1s):301A. Abstract no. 1282.

23. * Vaughan J, Harrington AM, Kroft SH, Olteanu H. Immunophenotypic Stability of Sezary Cells by Flow Cytometry. Modern Pathology. 2011; 24:326A.

24. * Schur BC, Harrington AM, Kroft SH, Olteanu H. Lymphocyte Subset Reference Ranges for Evaluation of Immune Reconstitution after Allogeneic Stem Cell Transplantation. Modern Pathology. 2011; 24:455A.


Page 34 of 36

RE-AIMS 9/1/2021 9:59:14 AM

25. Chang JC, Harrington AM, Olteanu H, Kroft SH. Proliferation Centers in Bone Marrows Involved by Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Clinicopathologic Analysis. Modern Pathology. 2011; 24:289A.

26. * Harrington AM, Olteanu H, Eshoa C, Kroft SH. The Unique Immunophenotype of "Double-Hit Lymphomas". Modern Pathology. 2011; 24:300A.

27. Vaughan J, Olteanu H, Kroft SH, Harrington AM. Blast Immunophenotypes by Flow Cytometry in Acute Myeloid Leukemia with Myelodysplasia-Related Changes. Modern Pathology. 2012; 25:377A.

28. Olteanu H, Harrington AM, Kroft SH. CD200 Expression in Non-Myeloma Immunoproliferative Disorders. Modern Pathology. 2012; 25:358A-359A.

29. Vaughan J, Olteanu H, Kroft SH, Harrington AM. Flow Cytometric Blast Immunophenotype in Acute Myeloid Leukemias Arising from Non-Acute Myeloid Disorders. Modern Pathology. 2012; 25:378A.

30. * Parsons LN, Olteanu H, Kroft SH, Harrington AM. Megakaryocytic Hyperplasia Associated with Granulocyte-Colony Stimulating Factor. Modern Pathology. 2012; 25:360A.

31. Rathke SK, Olteanu H, Kroft SH, Harrington AM. Morphologic Changes in Myelodysplastic Syndrome Treated with Hypomethylating Agents. Modern Pathology. 2012; 25:364A.

32. Harrington AM, Olteanu H, Kroft SH. Most Diffuse Large B-Cell Lymphomas Are Identified by Flow Cytometry. Modern Pathology. 2012; 25:339A.

33. Olteanu H, Harrington AM, Kroft SH, Karandikar NJ, Fuda FF. The Prevalence of CD56 Expression by Flow Cytometry in Acute Promyelocytic Leukemia Patients Treated with All-Trans Retinoic Acid and Anthracycline Drug Combinations. Modern Pathology. 2012; 25:359A.

34. * Horna P, Kroft SH, Harrington AM, Olteanu H. Persistence of Residual Normal Peripheral Blood B Cells in Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Identifies a Good Prognostic Subgroup. Mod Pathol. 02/01/2012; 25(S2):341A. Abstract no. 1428.

35. Vaughan J, Harrington A, Olteanu H, Kroft SH, Hess MA, Miller RA. A Retrospective Analysis of the Utility of Pathology Review Criteria for Peripheral Blood and Body Fluids: One Institution's Experience. American Journal of Clinical Pathology. 2012; 138:A087.

36. * Vaughan J, Mackinnon AC, Harrington AM, Kroft SH, Olteanu H. CD200 Expression in Post-Transplant Lymphoproliferative Disorders Correlates with an Increased Frequency of FoxP3(+) Regulatory T-Cells. Modern Pathology. 2013; 26:365A.

37. * Hintzke M, Fenske T, Kroft SH, Olteanu H, Harrington AM. CD30 Expression in Non-Hodgkin B-Cell Lymphoma. Modern Pathology. 2013; 26:331A-332A.

38. Rathke SK, Harrington AM, Olteanu H, Kroft SH. Dim CD33 Expression in Myelomonocytic Marrow Elements: A Novel Description of an Apparently Normal Variant. Modern Pathology. 2013; 26:356A-357A.

39. * Schumann J, Harrington AM, Kroft SH, Olteanu H. NK Cell Reference Ranges Established by Flow Cytometry in Reactive and Lymphomatous Lymph Nodes. Modern Pathology. 2013; 26:360A.

40. Rathke SK, Chang JC, Harrington AM, Olteanu H, Kroft SH. The Immunophenotype of Prolymphocytoid Transformation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Revisited. Modern Pathology. 2013; 26:357A.

41. Olteanu H, Vaughan J, Kroft SH, Fuda F, Harrington AM. Immunophenotypic Analysis of Mycosis Fungoides in Large Cell Transformation. American Journal of Clinical Pathology. 2013; 140:129.

42. Ordobazari A, Olteanu H, Kroft SH, Harrington AM. A Comparison of Therapy-Related and De Novo Chronic Myelomonocytic Leukemia. Modern Pathology. 2014; 27:369A.

43. * Li H, Kroft SH, Harrington AM, Hosking P, Olteanu H. Pure Erythroid Leukemia Evolving from Chronic Myeloid Neoplasms: A Report of 3 Cases. Modern Pathology. 2014; 27:357A-358A.

44. * Batdorf B, Kroft S, Hosking P, Harrington A, Mackinnon A, Olteanu H. Evaluation of CD43 Expression in Non-Hematologic Malignancies. American Journal of Clinical Pathology. 2014; 142.

45. Batdorf B, Kroft S, Olteanu H, Harrington A. Reactive Bone Marrow Plasmacytosis: An Update for the Modern Era. American Journal of Clinical Pathology. 2014; 142.

46. Hintzke M, Olteanu H, Kroft SH, Harrington AM. Sensitivity and Specificity of Peripheral Blood Findings in Screening for Myelodysplastic Syndrome. American Journal of Clinical Pathology. 2014; 142.

47. Merzianu M, Cheney R, Groman A, Deeb G, Wilding G, Cotta C, Amre R, Balasubramanian M, Brandao G, Brynes R K, Cherian S, Courville E, Czuchlewski D, Fan G, Grier D, Hoehn D, Hutchison RE, Inamdar KV,


Page 35 of 36

RE-AIMS 9/1/2021 9:59:14 AM

Juskevicius R, Kaur P, Lazarchick J, Lewis MR, Miles RR, Myers JB, Nasr M, Naushad H, Olteanu H, Orazi A, Reddy VVB, Robu VG, Salaru G, Teruya-Feldstein J, Vajpayee N, Vos J, Zhang L, Zhang SX, Sedelmeyer AV, Arguello V, Aye L, Barouk S, Brega EF, Carpenter R, Coad JE, DiPonio A, Garcia F, Grantham J, Ivelja S, McKenna R, Sultan K, Thomsen MB, Xu J, Peterson L, Neppalli VT. Bone Marrow Core Biopsy Adequacy and Variability in the United Stated and Canada: A Multicenter Retrospective Study. Blood. 2014; 124(21).

48. Harrington A, Shewmake A, Hosking P, Olteanu H, Kroft S. CD3 Staining on Myeloid Elements in Acute Myeloid Leukemia Bone Marrows. Modern Pathology. 2015; 28:348A.

49. * Hartley C, Hintzke M, Vaughan J, Hosking P, Harrington A, Kroft S, Olteanu H. CD30 Expression in Post-Transplant Lymphoproliferative Disorders. Modern Pathology. 2015; 28:349A.

50. * Li H, Kroft SH, Harrington AM, Hosking P, Olteanu H. CD38 Expression in Follicular Lymphoma Correlates With Histologic Grade. Modern Pathology. 2015; 28:359A.

51. * Robin A, Kroft SH, Harrington AM, Hosking P, Olteanu H. Evaluation of Proliferation Index in Lymph Nodes With CLL/SLL. Modern Pathology. 2015; 28:374A.

52. Harrington AM, Olteanu H, Hosking P, Kroft S. Unique Aberrant Myeloblast Immunophenotype Associated With Azathioprine Therapy. Modern Pathology. 2015; 28:349A.

53. Hintzke M, Hosking P, Olteanu H, Harrington A, Kroft SH. Bone Marrow Monocytosis: A Survey of 150 Cases. American Journal of Clinical Pathology. 2015; 144:A150.

54. Schelling L, Ordobazari A, Kroft SH, Olteanu H, Hosking P, Harrington AM. Immunophenotypic Comparison of Dysplastic and Proliferative Subtypes of Chronic Myelomonocytic Leukemia by Flow Cytometry. American Journal of Clinical Pathology. 2015; 144:A161.

55. * Batdorf B, Gheorghe G, Kroft S, Harrington A, Olteanu H, Hosking P. Correlation of CD79a Expression with Additional B-Cell Markers and Bruton's Tyrosine Kinase Expression in T-Cell Lymphoblastic Leukemia/Lymphoma. Modern Pathology. 2016; 29:335A.

56. Olteanu H, Hosking P, Harrington AM, Kroft SH. PD-L1 Expression Correlates with EBV Status in Post-Transplant Lymphoproliferative Disorders. Modern Pathology. 2016; 29:366A.

57. Olteanu H, Mboko W, Tarakanova V, Hosking P, Harrington AM, Kroft SH. Tumor Suppressor IRF-1 Expression Is Decreased in Post Transplant Lymphoproliferative Disorder. Modern Pathology. 2016; 29:366A.

58. * Epperla N, Fenske TS, Olteanu H, Pruett J, Goff A, Zellner K, Hamadani M, Shah NN. Outcomes of Grade 3A Follicular Lymphoma: Best Treated As Aggressive or Indolent Lymphoma? Blood. 2016; 128(22).

59. Kharfan-Dabaja MA, Raj RV, El-Jurdi N, Majhail N, Kumar A, Darrah J, Ayala E, de Lima M, Nishihori T, Parameswaran NH, Olteanu H, Zhang L, Sokol L, Hamadani N, Al-Malki M. A multicenter retrospective study of allogeneic hematopoietic cell transplantation in blastic plasmacytoid dendritic cell neoplasm. Bone Marrow Transplantation. 2017; 52:S386-S387.

60. Hopp AM, Olteanu H, Harrington AM, Kroft SH. Comparative Evaluation of Plasmacytoid Dendritic Cell Content in Reactive and Neoplastic Lymphoid Aggregates in Bone Marrow (BM). Modern Pathology. 2018; 31:522.

61. * Carrillo LF, Mendoza D, Olteanu H, Harrington A, Kroft SH. Computer-Based Differential Tally Counter for Bone Marrows. Modern Pathology. 2018; 31:585.

62. Carrillo LF, Harrington A, Olteanu H, Kroft SH. Evaluation of Extranodal Marginal Zone B Cell Lymphoma by Flow Cytometry. Modern Pathology. 2018; 31:503-504.

63. Olteanu H. Comparative evaluation of flow cytometry (fc) and morphology for detecting malignant cells in cerebrospinal fluid (csf) from patients with known hematologic neoplasms Laboratory Investigation. 2019 Mar; 99(Suppl 1):1351

64. Horna P, Shi M, Jevremovic D, Olteanu H. Single-Antibody Detection of T-Cell Receptor Beta Chain Monotypia Resolves Uncertainties in the Identification and Quantitation of Sézary Cells By Routine Flow Cytometry: Towards Accurate and Unequivocal Blood Staging of Cutaneous T-Cell Lymphomas Blood. 2019.

65. Shi M, Olteanu H, Jevremovic D, He R, Viswanatha D, Corley H, Horna P. Clinical utility of t-cell receptor constant beta chain-1 staining in the diagnosis of t-cell large granular lymphocytic leukemia by flow cytometry Laboratory Investigation. 2020 Mar; 100(SUPPL 1):1384-5

66. Berg H, Shi M, Horna P, Jevremovic D, Corley H, Otteson G, Olteanu H. Flow cytometric evaluation of trbc1 expression in tissue specimens and body fluids is a novel, sensitive and specific method for assessment of t-cell clonality and diagnosis of t-cell neoplasms Laboratory Investigation. 2020 Mar; 100(SUPPL 1):1255-6


Page 36 of 36

RE-AIMS 9/1/2021 9:59:14 AM

67. Qureshi R, Otteson G, Timm M, Shi M, Olteanu H, Kumar S, Jevremovic D. Quality parameters for flow cytometric minimal residual disease (mrd) assessment in plasma cell neoplasms Laboratory Investigation. 2020 Mar; 100(SUPPL 1):1367-8

68. Marissa Li, Terra Lasho, Alejandro Ferrer, Naseema Gangat, Aref Al-Kali, Abhishek Mangaonkar, Michelle Elliott, Mark Litzow, William Hogan, Animesh Pardanani, Alexandra Wolanskyj, Kaaren Reichard, Matthew Howard, Rebecca King, Mithun Shah, Hassan Alkhateeb, Kebede Begna, Ayalew Tefferi, Christy Finke, Moritz Binder, Horatiu Olteanu, Mrinal Patnaik. Clinical, Molecular, and Prognostic Comparisons between Clonal Cytopenias of Undetermined Significance and Lower-risk Myelodysplastic Syndromes - A Study of 184 Molecularly Annotated Patients 62nd ASH Annual Meeting. 2020.

69. Emma DiFilippo, Alejandro Ferrer, Laura Schultz-Rogers, Shakila Khan, Naseema Gangat, Aref Al-Kali, Abhishek Mangaonkar, Animesh Pardanani, Michelle Elliott, Mark Litzow, William Hogan, Alexandra Wolanskyj-Spinner, Phuong Nguyen, Kaaren Reichard, Matthew Howard, Rebecca King, Dong Chen, Rong He, David Viswanatha, Terra Lasho, Rajiv Pruthi, Pavel Pichurin, Teresa Kruisselbrink, Brendan Lanpher, Mark Wylam, Jennifer Oliveira, Dusica Babovic-Vuksanovic, Horatiu Olteanu, Mrinal Patnaik. Spectrum of Hematological Malignancies in 130 Patients with Germline Predisposition Syndromes- Mayo Clinic Germline Predisposition Study 62nd ASH Annual Meeting Abstract#: 139050. 2020.

Letters 1. Walters M, Olteanu H, Van Tuinen P, Kroft SH. CD23 expression in plasma cell myeloma is specific for

abnormalities of chromosome 11, and is associated with primary plasma cell leukaemia in this cytogenetic sub-group. Br J Haematol 2010 Apr; 149 (2):292-3 Epub 2010 Jan 08 PMID:20064156 DOI:10.1111/j.1365-2141.2009.08042.x

2. Morice WG, Jevremovic D, Olteanu H, Roden A, Nowakowski G, Kroft S, Hanson CA, Kurtin PJ. Chronic lymphoproliferative disorder of natural killer cells: a distinct entity with subtypes correlating with normal natural killer cell subsets. Leukemia 2010 Apr; 24 (4):881-4 Epub 2010 Jan 28 PMID:20111066 DOI:10.1038/leu.2009.304

3. Olteanu H, Harrington AM, Ramirez S, Kroft SH, Hari P. Efficacy and safety of long-term (>7 year) alemtuzumab therapy for refractory T-cell large granular lymphocytic leukaemia. Br J Haematol 2010 Aug; 150 (4):480-1 Epub 2010 Apr 28 PMID:20456357 DOI:10.1111/j.1365-2141.2010.08218.x

4. * Spears MD, Harrington AM, Kroft SH, Olteanu H. Immunophenotypic stability of T-cell large granular lymphocytic leukaemia by flow cytometry. Br J Haematol 2010 Oct; 151 (1):97-9 Epub 2010 July 16 PMID:20636433 DOI:10.1111/j.1365-2141.2010.08307.x

5. Harrington AM, Olteanu H, Kroft SH, Eshoa C. The unique immunophenotype of double-hit lymphomas. Am J Clin Pathol 2011 Apr; 135 (4):649-50 PMID:21411790 DOI:10.1309/AJCPL11MAHISIJBQ

6. Olteanu H, Harrington AM, Kroft SH. Immunophenotypic stability of CD200 expression in plasma cell myeloma. Am J Clin Pathol 2012 Jun; 137 (6):1013-4 PMID:22586062 DOI:10.1309/AJCP8TF3WUIWLZHU

7. Hari P, Raj RV, Olteanu H. Targeting CD38 in Refractory Extranodal Natural Killer Cell-T-Cell Lymphoma. N Engl J Med 2016 Oct 13; 375 (15):1501-1502 PMID:27732828 DOI:10.1056/NEJMc1605684

8. Kanate AS, DiGilio A, Ahn KW, Al Malki M, Jacobsen E, Steinberg A, Hamerschlak N, Kharfan-Dabaja M, Salit R, Ball E, Bashir Q, Cashen A, Couriel D, Diez-Martin J, Katsanis E, Linhares Y, Mori S, Nash R, Pawarode A, Perales MA, Phipps CD, Richman C, Savani BN, Shapira MY, Stiff P, Strair R, Fenske TS, Smith SM, Sureda A, Olteanu H, Hamadani M. Allogeneic haematopoietic cell transplantation for extranodal natural killer/T-cell lymphoma, nasal type: a CIBMTR analysis. Br J Haematol 2018 Sep; 182 (6):916-920 Epub 2017 Aug 02 PMID:28771676 DOI:10.1111/bjh.14879

Thesis 1. Olteanu H. Aquaporin-mediated water transport in erythrocyte membranes: A comparative NMR study in frog

and rainbow trout "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. September 1996;

2. Olteanu H. Biochemical studies of human methionine synthase reductase University of Nebraska - Lincoln, Lincoln, NE. May 2003;

Book Reviews 1. Olteanu H. Flow Cytometry in Clinical Diagnosis, 4th ed. Lab Medicine. 2008; 39(8):507.

* Indicates that the primary author was a mentee of this author.

Olteanu.pdf - International Clinical Cytometry Society

Documents

Transcript of Olteanu.pdf - International Clinical Cytometry Society