ANTIOKSIDAN DAN NILAI IC50

DARI BERBAGAI TURUNAN HIDROKSIKALKONStruktur Senyawa IC50 (1x10-5 M) Metode No

Mr = 224 g/mol

9% (5x10-3 M) (2)

100,08 ppmDPPH 1a

Mr = 224 g/mol

500 (1)

1120 ppmDPPH 2a

Mr = 224 g/mol

1% (5x10-3 M) (2)

11,2 ppmDPPH 3a

Mr = 240 g/mol

7% (5x10-3 M) (2)

84 ppmDPPH 4a

Mr = 256 g/mol

5.0 (1)

12,8 ppm DPPH 5a

Mr = 256 g/mol

11% (5x10-3 M) (2)

28,16 ppm DPPH 6a

Mr = 272 g/mol

2.7 (1)

7,34 ppmDPPH 7a

Mr = 272 g/mol

100.0 (1)

272 ppm DPPH 8a

Mr = 288 g/mol

3.1 (1)

8,93 ppm DPPH 9a

Mr = 286 g/mol

13.0 (1)

37,18 ppm DPPH 10a

a) David Kozlowski, Patrick Trouillas, Claude Calliste, Philippe Marsal, Roberto Lazzaroni, and Jean-Luc Duroux, Density Functional Theory Study of the Conformational, Electronic, and Antioxidant Properties of Natural Chalcones J. Phys. Chem. A 2007, 111, 1138-1145

1. IC50 represents the chalcone concentration required to reduce the DPPH electron spin resonance (ESR) signal by 50%. Standard deviations are <10%.

2. Values given in brackets represent the inhibition percentage at 5x10 -3 M for compounds with IC50

>500.0 x 10-5

96.38(µg/mL) DPPH 11b

107(µg/mL) DPPH 12b

88.41(µg/mL) DPPH 13b

86.70(µg/mL) DPPH 14b

96.24(µg/mL) DPPH 15b

a) Belsare D .P., Pal S.C.,Kazi A .A., Kankate R.S.,Vanjari S.S, Evaluation of Antioxidant Activity of Chalcones and Flavonoids, International Journal of ChemTech Research, 2010, Vol.2, No.2, pp 1080-1089