Title of Research: Investigating patterns of Cardiovascular disease linked mortality in London.

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Cardiovascular disease (CVD) mortality rates in London An investigation into the distribution of mortality across the different London boroughs Joshua Valverde University of Bristol Email: [email protected]

Transcript of Title of Research: Investigating patterns of Cardiovascular disease linked mortality in London.

Cardiovascular disease (CVD) mortality rates

in LondonAn investigation into the distribution of

mortality across the different London boroughs

Joshua ValverdeUniversity of Bristol

Email: [email protected]

Aims •To identify patterns in the distribution of CVD mortality, in terms of general spatial gradients.

•To correlate influencing factors with CVD mortality. •The factors were: ethnicity, socio-economic deprivation, lifestyle habits and geodemographics.

•To attempt to explain the underlying causes of CVD specific to London.

•To, perhaps, extend this model to other cities and perhaps other diseases of affluence.

Definitions•Disease of affluence: a disease which is brought about by the lifestyle changes associated with wealth (such as increased meat consumption), they usually considered non-infectious.

•CVD: a group of diseases related to failure of the heart and blood vessels. Diseases include Coronary Heart Disease (CHD), stroke and hypertension.

•Depravation: a primarily economic measure of wealth. Rated on a scale of 1-5 with 1 being the most deprived.

•Geodemographics: this is a classification of the population into groups based on their lifestyle and age. E.g. ‘Multicultural urban’

•Meta-analysis: a study which focuses on multiple data sets, comparing and contrasting them to understand general trends and patterns and place them in appropriate context.

Methods •Transects were made along main arterial routes out of London: A1, A3, A13, A40. They represent routes which are northbound, southbound, eastbound and westbound respectively from central London.

•The gross mortality rate was graphed along each transect, and the data from influencing factors was used to support correlative data or try to explain anomalous data. Data was analysed using r2 polynomial regression analysis.

•The main source of data has come from publically accessible “Cardiovascular disease PCT health profiles” compiled by the South East Public Health Observatory (SEPHO).

© OpenStreetMap contributors

© OpenStreetMap contributors

Source - BBC Bitesize- © [2014] BBC

Source - BBC Bitesize- © [2014] BBC

Graphs of mortality

City and Hackney

Islington Haringey Barnet

100.4 11

9.3

85.8

51.5

R² = 0.945977137431065

CVD mortality rate for boroughs along the A1CVD mortality rate per 100000Polynomial (CVD mortality rate per 100000)

City and Hackney

Tower Hamlets

Newham Barking and

Dagenham

Havering

100.4 113.6

116

100.8

67.9

R² = 0.996329550034049

CVD mortality rate for boroughs along the A13

CVD mortality rate per 100000Polynomial (CVD mortality rate per 100000)

City and Hackney

Southwark

Lambeth

Wandsworth

Richmond and Twickenham

Kingston upon Thames

0

20

40

60

80

100

120

R² = 0.789190695784506

CVD mortality rate for boroughs along the A3

CVD mortality rate per 100000Polynomial (CVD mortality rate per 100000)

0

20

40

60

80

100

120

R² = 0.362873022905306

CVD mortality rates for boroughs along the A40

CVD mortality rate per 100000

Polynomial (CVD mortality rate per 100000)

City and Hackney

Camden Westminster Kensington and Chelsea

Hammersmith and Fulham

Ealing Hillingdon Average A400.00%

10.00%

20.00%

30.00%

40.00%

50.00%

60.00%

70.00%

9.40%11.90% 11.30%

6.90% 5.60%

23.10%

15.30%11.93%

White Black Asian Other

City and Hackney

Southwark

Lambeth

WandsworthRichmond and Twickenham

Kingston upon Thames

Average A3

Smoking Binge DrinkingObesity Unhealthy Eating

City and Hackney

Southwark Lambeth Wandsworth Richmond and

Twickenham

Kingston upon

Thames

Average A30.00%

10.00%

20.00%

30.00%

40.00%

50.00%

60.00%

70.00%

80.00%

90.00%

100.00%

Mature City ProfessionalsEductional CentresYoung City ProfessionMulticultural SuburbiaMulticultural Inner CityMulticultural UrbanSuburbia

Results •The general mortality rate was had a strong r2 correlation coefficient, using a quadratic model.

•Ethnicity was a strong indicator of CVD mortality with certain groups being both more generally likely to die from CVD, and certain groups suffering from a particular CVD.

•Deprivation was found to correlate strongly to CVD mortality with no major anomalies.

•Lifestyle habits and geodemographics showed no clear trends or stark contrasts along the transects.

Conclusions•There seems to be an inner city zone where CVD mortality is prevalent.

•Anomalies are found mainly in the westward transect (A40) where Kensington and Chelsea breaks the trend, but there are socio-economic reasons which help to explain this.

•Ethnicity correlates well with CVD mortality, there are groups which are more at risk.

•The Hoyt model can be adjusted for London and forms a strong foundation for studying the distribution of disease in urban areas.

Source - BBC Bitesize- © [2014] BBC

Discussion •What is a disease of affluence?

•It seems that these diseases are more prevalent in developing countries where changes to diet and lifestyle are driving urbanisation.

•How do we advise and prevent these diseases?•Similarly to ‘smoking kills’ warning on cigarettes do we need to have more TV broadcasts towards healthy eating and lifestyle choices?

•How do we look at the mismatch between incidence and mortality in terms of the NHS?•Money seems to buy better health care, all over the world. However our situation is different because of the legacy of the NHS.

•At the end of the day is it genetic predisposition that has a deciding role in CVD mortality?•Mortality rates correlated most strongly with ethnicity.

Any Questions?

Useful Websites•Information on poverty and socio-economics: http://www.trustforlondon.org.uk/

•Information on CVD in London: http://www.sepho.org.uk/CVDprofiles.aspx