ROLE OF BASTI IN ULCERATIVE COLITI N ... - IAMJ....

6
International Ayurvedic Medical Journal ROLE OF BASTI IN ULCERAT N Kavya 1 , S. Vasan Satish 2 , B A L PG Scholar 1 , PG Scholar 2 , Head of th Sri Dharmasthala Manjunatheshwara Email: [email protected] Ulcerative Colitis is an Inflammatory lining of the colon and rectum. It known. Theories involve immune sy environmental factors. Together with Dietary changes may improve symp about and ing aminosalicylates suchas sulfasala logical therapy. Based on the clinic IBD with ulcerative colitis in Ayurv in treating Ulcerative colitis. The si washaya (colon). Dosha involved in vata sthana pakwashaya. Hence, tac And there is no treatment that is equ samsarga and sannipata condition dravyas and picchila guna. Also it im the dietary modifications, gives the m gata pitta, through basti intervention Keywords: panchakarma, IBD, ulce INTRODUCTION Ulcerative Colitis is an Inflamma Disease, which causes inflammation tion of inner lining of the colon a INTERNATIONAL AYURVEDIC MEDICAL JOURNAL l, (ISSN: 2320 5091) Volume 5, Issue 12, December, 20 TIVE COLITIS – A REVIEW Lohith 3 he Department 3 a Ayurvedic Medical College and Hospital, Hass ABSTRACT y Bowel Disease, which causes inflammation an is a long-term condition. The cause of Ulce ystem dysfunction, genetics, changes in the norm h Crohn's disease about 112 million people were ptoms. Several medications are used to treat s maintain remission, azine, steroids, immunosuppressant such as aza cal signs and symptoms, the disease Pravahika veda. Panchakarma therapy aids as an importan ite of Ulcerative colitis is colon. The sthana of n ulcerative colitis is pitta dosha, so we can infe ckle the sthanika dosha first and followed by ual to basti in ayurveda. And through basti one ns. Piccha basti reduces inflammation due to mproves the function of Apana vata. Samshama maximum benefit. Hence, here is an effort made n erative colitis, pravahika, basti, piccha basti . atory Bowel n and ulcer a- and rectum. 1 The inflammation usually b and spreads upward to the disease can occur at any age 017 san, 573201 nd ulceration of inner erative colitis is un- mal gut bacteria, and e affected as of 2015. symptoms and bring includ- athioprine, and bio- can be correlated to nt treatment modality f vata dosha is Pak- er that pitta resides in treating pitta dosha. can treat eka dosha, o its grahi, deepana ana yogas, along with e to treat vata sthana begins in the rectum e entire colon. This e but its onset is most

Transcript of ROLE OF BASTI IN ULCERATIVE COLITI N ... - IAMJ....

International Ayurvedic Medical Journal, (

ROLE OF BASTI IN ULCERATIVE COLITIS N Kavya1, S. Vasan Satish2, B A Lohith PG Scholar1, PG Scholar2, Head of the DepartmentSri Dharmasthala Manjunatheshwara Ayurvedic Medical College and Hospital, Hassan, 573201 Email: [email protected]

Ulcerative Colitis is an Inflammatory Bowel lining of the colon and rectum. It is a longknown. Theories involve immune system dysfunction,environmental factors. Together with Crohn's disease about 112 million people were affected as of 2015. Dietary changes may improve symptoms. Several medications are used to treat symptoms and bringabout and maintain remission, incluing aminosalicylates suchas sulfasalazinelogical therapy. Based on the clinical signs and symptoms, the disease IBD with ulcerative colitis in Ayurveda. Panchakarmain treating Ulcerative colitis. The site of Ulcerative colitis is colon. The washaya (colon). Dosha involved in ulcerative colitis is vata sthana pakwashaya. Hence, tackle the And there is no treatment that is equal to samsarga and sannipata conditions.dravyas and picchila guna. Also it improves the function of the dietary modifications, gives the maximum benefit. Hence, here is an effort made to treat gata pitta, through basti intervention Keywords: panchakarma, IBD, ulcerative colitis, pravahika, basti, piccha basti INTRODUCTION Ulcerative Colitis is an Inflammatory Bowel Disease, which causes inflammation and ulcertion of inner lining of the colon and rectum.

INTERNATIONAL AYURVEDIC MEDICAL JOURNAL

International Ayurvedic Medical Journal, (ISSN: 2320 5091) Volume 5, Issue 12, December, 2017

ROLE OF BASTI IN ULCERATIVE COLITIS – A REVIEW

, B A Lohith3

, Head of the Department3

Sri Dharmasthala Manjunatheshwara Ayurvedic Medical College and Hospital, Hassan, 573201

ABSTRACT Ulcerative Colitis is an Inflammatory Bowel Disease, which causes inflammation and ulceration of inner lining of the colon and rectum. It is a long-term condition. The cause of Ulcerative colitis is u

immune system dysfunction, genetics, changes in the normal gut bacteria, anTogether with Crohn's disease about 112 million people were affected as of 2015.

Dietary changes may improve symptoms. Several medications are used to treat symptoms and bringbout and maintain remission, inclu

sulfasalazine, steroids, immunosuppressant such as azathioprineBased on the clinical signs and symptoms, the disease Pravahika

IBD with ulcerative colitis in Ayurveda. Panchakarma therapy aids as an important treatment modality in treating Ulcerative colitis. The site of Ulcerative colitis is colon. The sthana of

involved in ulcerative colitis is pitta dosha, so we can infer that . Hence, tackle the sthanika dosha first and followed by treating

And there is no treatment that is equal to basti in ayurveda. And through basti one can treat conditions. Piccha basti reduces inflammation due to its . Also it improves the function of Apana vata. Samshamana yogas

the dietary modifications, gives the maximum benefit. Hence, here is an effort made to treat intervention

panchakarma, IBD, ulcerative colitis, pravahika, basti, piccha basti.

matory Bowel isease, which causes inflammation and ulcera-

the colon and rectum.1

The inflammation usually begins in the rectum and spreads upward to the entire colon. This disease can occur at any age but its onset is most

Volume 5, Issue 12, December, 2017

Sri Dharmasthala Manjunatheshwara Ayurvedic Medical College and Hospital, Hassan, 573201

Disease, which causes inflammation and ulceration of inner term condition. The cause of Ulcerative colitis is un-

normal gut bacteria, and Together with Crohn's disease about 112 million people were affected as of 2015.

Dietary changes may improve symptoms. Several medications are used to treat symptoms and bring bout and maintain remission, includ-

azathioprine, and bio-Pravahika can be correlated to

therapy aids as an important treatment modality of vata dosha is Pak-

, so we can infer that pitta resides in first and followed by treating pitta dosha.

one can treat eka dosha, reduces inflammation due to its grahi, deepana

Samshamana yogas, along with the dietary modifications, gives the maximum benefit. Hence, here is an effort made to treat vata sthana

The inflammation usually begins in the rectum and spreads upward to the entire colon. This disease can occur at any age but its onset is most

N Kavya Et Al: Role Of Basti In Ulcerative Colitis – A Review

IAMJ: VOLUME 5, ISSUE 12, DECEMBER, 2017 4459

common among the people between ages of 15 - 40. Ulcerative colitis also appears to run in some families. Together with Crohn's disease about 112 million people were affected as of 2015. Each year it newly occurs in 1 to 20 per 100000 people, and 5 to 500 per 100,000 indi-viduals are affected2.

AIMS AND OBJECTIVES To understand the role of basti in the manage-ment of Ulcerative colitis METHODS AND METHODOLOGY The cause of UC is unknown. Theories in-

volve immune system dysfunction, genetics, changes in the normal gut bacteria, and envi-ronmental factors.3

Chromosome band 1p36 is one such region thought to be linked to inflammatory bowel disease.4

High intake of unsaturated fat and vitamin B6 may enhance the risk of developing ul-cerative colitis. The disease may also relapse or develop by the intake of meat protein and alcoholic beverages.

SYMPTOMS The symptoms are mainly of gastro-intestinal origin and extraintestinal origin. Gastro-intestinal symptoms include5

Diarrhea mixed with blood and mucus Bleed on rectal examination Anemia Abdominal pain Increased abdominal sounds Fever

Rectal pain Malnutrition Weight loss And Extraintestinal symptoms include6

Aphthous ulcer Ophthalmic Iritis Episcleritis Musculoskeletal Ankylosing spondylitis Sacroiliitis Cutaneous (related to the skin): Erythema nodosum Pyoderma gangrenosum TYPES Ulcerative colitis is normally continuous from the rectum up the colon. The disease is classi-fied by the extent of involvement, depending on how far the disease extends: Distal colitis, potentially treatable with

enemas7

Proctitis: Involvement limited to the rectum.

Proctosigmoiditis: Involvement of the recto-sigmoid colon, the portion of the colon adja-cent to the rectum.

Left-sided colitis: Involvement of the de-scending colon, which runs along the pa-tient's left side, up to the splenic flexure and the beginning of the transverse colon.

Extensive colitis, inflammation extending beyond the reach of enemas:

Pancolitis: Involvement of the entire colon, extending from the rectum to the cecum, be-yond which the small intestine begins.

N Kavya Et Al: Role Of Basti

IAMJ: VOLUME 5, ISSUE 12, DECEMBER, 2017

DIAGNOSTIC TOOL The best test for diagnosis of ulcerative colitis remains Endoscopy. LEAD PIPE SIGN Lead pipe appearance of colon is the class

cal barium enema finding in chronic ulcertive colitis

There is complete loss of haustralTREATMENT8

Dietary changes Aminosalicylates – sulfasalazine Steroids Immunosuppressants – azathioprine Biological therapy Surgery AYURVEDIC PERSPECTIVE IBD can be correlated to Grahan Vyavachedaka nidana (Differential diagn

sis) o Pittaja grahani o Rakta atisara o Pravahika It can be correlated to the diease Pravahika which manifests in the form of Atipravahana of Purisha (repeated defection), Atidrava Purisha Pravrittistool), Udarashoola (pain abd

N Kavya Et Al: Role Of Basti In Ulcerative Colitis – A Review

E 12, DECEMBER, 2017

The best test for diagnosis of ulcerative colitis

Lead pipe appearance of colon is the classi-cal barium enema finding in chronic ulcera-

There is complete loss of haustral markings

sulfasalazine

azathioprine

Grahani dosha Differential diagno-

It can be correlated to the dis-which manifests in the form

(repeated defeca-Atidrava Purisha Pravritti (watery

(pain abdo-

men), Picchila, Saphena (sticky and frothy), and Raktayukta Purisha (bloodPRAVAHIKA In the person who indulges in unhealthy foods, vata getting aggravated, pushes the kapha accmilated (in the pakvasayadownwards again and again after straining and mixed with faeces; this disease is called hika.10

TYPES Pravahika produced by vataduced by pitta has burning sensation, that prduced by kapha has eliminatwith kapha and that produced by blood mixed with faeces; these kinds are prduced by more of unctuousness and dryness (in the large intestine) their signs/symptoms, metods of treatment and features of and pakwa (ripe) stages are similar to those ofatisara (diarrhoea).11 CHIKITSA SUTRA That pravahika which does not subside by vilanghana etc (fasting and other thinning methods) or gets increased by the use of Pachana (digestive medicines), becomes su

4460

(sticky and frothy), (blood-mixed stool).9

In the person who indulges in unhealthy foods, vata getting aggravated, pushes the kapha accu-

pakvasaya – large intestine) downwards again and again after straining and mixed with faeces; this disease is called prava-

vata has pain, that pro-has burning sensation, that pro-has elimination of faeces mixed

and that produced by rakta has blood mixed with faeces; these kinds are pro-duced by more of unctuousness and dryness (in the large intestine) their signs/symptoms, meth-ods of treatment and features of ama (unripe)

ipe) stages are similar to those of

which does not subside by etc (fasting and other thinning

methods) or gets increased by the use of (digestive medicines), becomes sub-

N Kavya Et Al: Role Of Basti In Ulcerative Colitis – A Review

IAMJ: VOLUME 5, ISSUE 12, DECEMBER, 2017 4461

sided quickly by the use of boiled milk, oil (of sesame) and piccha basti (slimy enema).12 PICCHA BASTI13

INGREDIENTS DOSAGE MAKSHIKA 200ml

SAINDHAVA 15gms SNEHA 200ML - jathyadi taila KALKA 30GMS - pippali, bilva, kushta, satahva, vaca

KWATHA shalmali kashaya

Piccha basti kashaya can be prepared using two procedures. One is by the Putapaka method and the other by regular kashaya preparation method. Putapaka method of extracting swarasa is done by enveloping Shalmali vrunta in kusha variety of grass and then it is subjected to puta. When the pishti cools down on its own, the juice

is extracted manually. This swarasa is mixed with other ingredients of Piccha basti. Piccha basti is indicated in jeerna atisara avastha and jeerna grahani by Charaka and Vagbhata, but according to Sushrutha, he has mentioned it in the context of pravahika. It acts as grahi and contains deepana and pachana drugs.

KSHEERA BASTI14

DISCUSSION IBD can be considered as Grahani dosha in Ay-urveda15. According to Ayurveda, Ulcerative colitis is a disease of Purishavaha srotas16. It is primarily a disease of Pitta dosha with varying degrees of Vata involvement. The latter deter-mines how extensively the inflammatory proc-ess will spread proximally and the development of extra intestinal manifestations. The excessive consumption of Pittaja ahara and vihara ini-tially damages both rakta dhatu (blood tissue) and mamsa dhatu (muscle tissue), leading to formation of ama that gets deposited between the villi in the intestines, forming a smooth coat-

ing that impairs the normal function and immu-nity of the intestines. Vata Dosha in the lower colon is also aggravated and in the early stages blocks the Pitta and Kapha channels, causing inflammation, mucous accumulation and edema. The site of Ulcerative colitis is colon. The sthana of vata dosha is Pakwashaya (colon). Dosha involved in ulcerative colitis is pitta dosha, so we can infer that pitta resides in vata sthana pakwashaya. Hence, tackle the sthanika dosha first and followed by treating pitta dosha. And there is no treatment that is equal to basti in treating vata dosha. And through basti one can treat eka dosha, samsarga and sannipata condi-

INGREDIENTS DOSAGE MAKSHIKA 100ML SAINDAVA 12GMS SNEHA 100ML – changeryadi gritha, yastimadhu taila KALKA 40GMS – guduchi, yastimadhu, arjuna, manjishta KWATHA 300ML – yastimadhu ksheerapaka

N Kavya Et Al: Role Of Basti In Ulcerative Colitis – A Review

IAMJ: VOLUME 5, ISSUE 12, DECEMBER, 2017 4462

tion. In Ayurveda, Raktatisara is mentioned as an advanced stage of Pittatisara. Piccha basti is mentioned as a management of Raktatisara in Charaka Samhita17. Piccha basti reduces inflammation due to its grahi, deepana dravyas and picchila guna. Also it im-proves the function of Apana vata. Samshamana yogas, along with the dietary modifications, gives the maximum benefit. CONCLUSION Based on the clinical signs and symptoms, the disease Pravahika can be correlated to IBD with ulcerative colitis. Pravahika is a disease with the involvement of kapha, pitta and vata associ-ated with agnimandya. Hence, the line of treat-ment mainly includes pachana and sangrahi dravya. Piccha basti reduces inflammation due to its grahi, deepana dravyas and picchila guna. Also it improves the function of Apana vata. Samshamana yogas and along with the dietary modifications, gives maximum relief. REFERENCES 1. "Ulcerative Colitis". NIDDK. September

2014. Archived from the original on 28 July 2016. Retrieved 3 August 2016.

2. Ford, AC; Moayyedi, P; Hanauer, SB (5 February 2013). "Ulcerative colitis.". BMJ (Clinical research ed.). 346: f432.PMID 23386404. doi:10.1136/bmj.f432

3. Akiho, Hirotada; Yokoyama, Azusa; Abe, Shuichi; Nakazono, Yuichi; Murakami, Ma-satoshi; Otsuka, Yoshihiro; Fukawa, Kyoko; Esaki, Mitsuru; Niina, Yusuke (2015-11-15). "Promising biological therapies for ul-cerative colitis: A review of the litera-ture". World Journal of Gastrointestinal Pathophysiology. 6 (4): 219–227.ISSN 2150-5330. PMC 4644886 

. PMID 26600980.doi:10.4291/wjgp.v6.i4.219

4. Cho JH, Nicolae DL, Ramos R, Fields CT, Rabenau K, Corradino S, Brant SR, Espinosa R, LeBeau M, Hanauer SB, Bodzin J, Bonen DK (2000). "Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease" (PDF). Human Molecular Genetics. 9 (9): 1425–32.PMID 10814724. doi:10.1093/hmg/9.9.1425

5. Hanauer SB (1996). "Inflammatory bowel disease". The New England Journal of Medicine. 334 (13): 841–8. PMID 8596552.doi:10.1056/NEJM199603283341307

6. Langan RC, Gotsch PB, Krafczyk MA, Skillinge DD (November 2007). "Ulcerative colitis: diagnosis and treat-ment" (PDF).American Family Physi-cian. 76 (9): 1323–30. PMID 18019875.Archived (PDF) from the original on 20 May 2013.

7. Kornbluth A, Sachar DB (2004). "Ulcera-tive colitis practice guidelines in adults (up-date): American College of Gastroenterol-ogy, Practice Parameters Committee". The American Journal of Gastroenterol-ogy. 99 (7): 1371–85. PMID 15233681.doi:10.1111/j.1572-0241.2004.40036.x

8. Danese, S; Fiocchi, C (3 November 2011). "Ulcerative colitis.". The New England Journal of Medicine. 365 (18): 1713–25.PMID 22047562. doi:10.1056/NEJMra1102942

9. Pooja B A, Bhatted S. Ayurvedic manage-ment of Pravahika – A case report. AYU 2015;36:410-2

N Kavya Et Al: Role Of Basti In Ulcerative Colitis – A Review

IAMJ: VOLUME 5, ISSUE 12, DECEMBER, 2017 4463

10. Acharya YT, editor. Sushrutha Samhita of Sushrutha, Uttara Tantra, Ch. 40, Ver. 138. 2nd ed. Varanasi: Chaukhamba Sanskrit Sansthan; 2004. p.243.

11. Acharya YT, editor. Sushrutha Samhita of Sushrutha, Uttara Tantra, Ch. 40, Ver. 139-140. 2nd ed. Varanasi: Chaukhamba Sanskrit Sansthan; 2004. p.243.

12. Acharya YT, editor. Sushrutha Samhita of Sushrutha, Uttara Tantra, Ch. 40, Ver. 141. 2nd ed. Varanasi: Chaukhamba Sanskrit Sansthan; 2004. p.243.

13. Charaka Samhita Part II Chikitsa Sthana, Choukamba Orientalia, Varanasi, Chapter 14 Shloka 228, pg no. 246.

14. Yadaiah P, Clinical Panchakarma, Jaya Pub-lications, Akola – 444005, p. 88.

15. Mahima S.B. Et.al. A Critical Review On Takra Prayoga In Grahani Roga. Interna-

tional Journal of Ayurvedicand Herbal Medicine 7:4 (2017) 2656–2662

16. Manish V. Patel. Et.al. Effects of Ayurvedic treatment on forty-three patients of ulcera-tive colitis. Ayu. 2010 Oct-Dec; 31(4): 478–481

17. Charaka Samhita Part II Chikitsa Sthana, Choukamba Orientalia, Varanasi, Chapter 19, Shloka 63-68, pg no.338.

Source of Support: Nil Conflict Of Interest: None Declared

How to cite this URL: N Kavya Et Al: Role Of Basti In Ulcerative Colitis – A Review. International Ayurvedic Medical Journal {online} 2017 {cited December, 2017} Available from: http://www.iamj.in/posts/images/upload/4458_4463.pdf