lesiputihppdgs08

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    Program Pendidikan S pesialis Dokter Gigi

    Departemen Ilmu Penyakit Mulut FKGUI

    Yuniardini S Wimardhani200

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    LES I PUTIH !"#"DI$%#Y W!I$" &"S I'(

    #"%)$I*"+I(F&%MM%$'#Y W!I$"&"SI'(

    De,elopmental -hite les ion Gingi,al and palatal .yst o/ ne-orn and

    adult Mis.ellaneous lesions

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    HE R ED ITAR Y WHITE

    LES ION

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    Un.lear etiology (ormal ,ariation

    Features1 ilateral3 u..al

    mu.osa Faint3 -hite3 di//use3

    /ilmy appearan.e3/olded-rinkling

    mu.osa 4s.rapped o//3

    /ade+disappear onstre.thing

    %symptomati.3 no

    malignant .hange

    Mi.ros.opi.ally1 $hi.kening epith

    parakeratosis "dema intra.ellular at

    stratum spinosum

    $reatment1 (o treatment

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    #are autosomal disorder 5a//e.t non6.orni/ied epith Identi/ied at irth3 5 intense

    at puerty #elated -ith K7 and K89

    gene disturan.es

    Features White lesion3 ele,ated3

    irregular /issures pla:ue u..al mu.osa Dysphagia i/ esophagus

    in,ol,ed DD+ -ith leukoplakia3

    pla:ue type .andidias is

    Mi.ros.opi.ally1 ',ious intra.elullar

    edema o/ 55stratumspinosum

    Pyknoti. nu.lei (o+mild in/iltration o/

    in/lammation .ells

    Management1(o treatment enign .ondt;n %ntiioti. in se,eral

    studiesno .ons istentresults

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    < Witkop;s disease #are autosomal

    dominant disorderFeatures1 $hi.k3 .orrugated3

    asymptomati. -hitespongy pla:ue o/u..al=laial mu.osa

    Dete.ted at 8styear o/

    li/e3 55intense untilteens

    ular .on>u.ti,alesion

    '..ular irritation3

    photophoia3 lindness

    Mi.ros.opi.ally1 Parakeratinised S tratum spinosum

    thi.kening -ith

    dyskeratoti. /eatures

    Management1'ral les ion1 no treatment'..ular lesion

    opthalmologist

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    #are ?6linked Genodermatosis 'ral .hanges erythro+leukoplakia

    Dysthropi. nails3 hyperpigmentation o/skin @/a.e3 ne.k3 .hestA

    !aematologi. .hanges )ar.inoma in early adulthood

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    R EA C TIVE /IN FLAM M ATORY

    WHITE LES ION

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    &inea ala3 /ri.tional keratosis3 .heek

    .he-ing3 .hemi.al in>uries o/ oral mu.osa3

    a.tini. keratos is3 smokeless toa..oindu.ed keratosis3 ni.otine stomatitis3

    sanguinaria indu.ed leukoplakia

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    a -hite horiBontal

    streak on the u..al3

    o..lusal plane asso.iated -ith

    pressure3 /ri.tional

    irritation3 su.king

    trauma 5 in C o,er>et

    Management1 (o treatment May disappear

    spontaneously

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    a -hite pla:ue3 rough

    sur/a.e3related to

    me.hani.al irritation

    usually resol,e onelimination o/ the irritant

    @rough or malad>usted

    dentures3sharp .usps

    and edges o/ roken

    teethA DD+ leukoplakia

    Mi.ros.opi.ally1 !yperkeratosis %.hantosis

    Management1 " limination o/ irritant iopsy /or 2 -eeks non

    healing les ion a/ter agent

    remo,al

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    .hroni. irritation su.king3

    niling3 or .he-ing

    thi.kened3 s.arred3 and

    paler mu.osa stress or in psy.hologi.al

    situationshaitual

    .heek iting &ateral tongueDD+

    '!& DD+WS (3 urns3

    .andidiasis

    Mi.ros.opi.ally1 hyperparakeratosis

    and a.anthos is shaggy and ragged

    keratin -+ adherent

    a.terial

    Manangement1 a plasti. o..lusal

    night guard &a in,est'!&

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    $rans ient non6

    keratoti. -hite

    les ions a result o/

    .hemi.al in>uries

    .austi. -hen

    retained in the mouth

    /or long periods

    aspirin3 sil,er nitrate3

    /ormo.resol3 sodium

    hypo.hlorite3

    para/ormaldehyde3

    dental .a,ity

    ,arnishes3

    a.idet.hing materials3and hydrogen

    peroEide

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    premalignantepithelial les ion

    long6term sun

    eEposure iopsieslesions

    repeatedly ul.erate3.rust o,er3 -ith

    thi.kened -hite area People -+outdoor

    o..upations 3 and+or/air .ompleEions

    Mi.ros.opi.ally1 %trophi. epithelium &amina propria1

    elastos is+asophili.homogenousamorphous alterationo/ the .ollagen

    Dysplasti. /eatures

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    -hite mu.osal les ionin the area o/toa..o .onta.t

    /ound in haitualusers o/ smokelesstoa..o

    %nterior mandiular

    posterior )essationnormal

    mu.osal 862-eeks 58moiopsy

    iopsy atypi.allesion1 ul.eration3erythroplakia3 intense

    -hiteness3 or a,erru.oid or papillary

    Malignanttrans/ormation 57E

    /or .hroni. smokelesstoa..o users

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    S anguinaria eEtra.t3

    a miEture o/

    enBophenanthridine

    alkaloids @/rom

    loodroot plant

    S anguinaria

    canadensis), used inoral rinses and

    toothpaste sin.e

    8H2 @eg *iadentA

    Indu.ing dysplasti.

    keratosis %,oid (o regression in

    some *iadent6

    indu.ed leukoplakias

    months a/ter the.essation o/ *iadent

    use

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    D"*"&'PM"($%& W!I$"

    &"SI'(

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    )ysti. e.topi. lymphoid tissue @oral

    lymphoepithelial .ystA 5posterior lateral order o/ the tongue @lingual

    tons ilA and Waldeyer;s ring@ tonsillar tissue

    1lingual3 pharyngeal3 palatine tonsilsA reddish yello- or -hite sumu.osal dome6

    shaped nodules Diagnosed1.lini.al /eatures large enough to re:uire a iopsyso/t palate

    irritation and it.hingremo,al

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    multiple sessile dome shaped lesions 2 to

    9 mm3 .halk -hite3 maEillary anterior

    al,eolar ridge >ust lingual to the .rest posterior region o/ the >a- on the .rest o/

    the ridge o..lusal to the .ro-ns o/ the

    molar teeth seen in ne-orn or ,ery young in/ants

    and disappear shortly a/ter irthJ originate

    /rom remnants o/ the dental lamina

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    .lini.al term

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    slo-ly progressi,e .hroni. /iroti. diseaseo/ the oral .a,ity and oropharynE3 -+/iroelasti. .hange and in/lammation o/the mu.osaprogressi,e inaility to openthe mouth3 s-allo-3 or speak

    *ery resistant to treatment

    e a premalignant .ondition oral .an.er de,eloped in L o/ patientsmalignant trans/ormation rate -as 7 to89

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