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Transcript of Deddi Prima Putra - muswilsumatera2.files.wordpress.com · Obat Tradisional (2000-2014) 0 5 10 15...
Disampaikan pada
Semnas dan Muswil ISMAFARSI Sumatera II
Fakultas Farmasi Unand- 23 April 2016
PADANG
Deddi Prima Putra
Penduduk Indonesia
Sumber : diolah dr BPS 2015*) Perkiraan
0 50 100 150 200 250 300 350
1971
1980
1990
1995
2000
2010
2015*
2020*
2025*
2030*
2035*
Persentase Penduduk yang Mengobati SendiriSelama Sebulan Terakhir (%)
0
5
10
15
20
25
30
35
40
45
50
Ind (rerata)
Sumbar
Sumber : diolah dr BPS 2015
Persentase penduduk yang mengalami keluhan kesehatan sebulan yang lalu
0 5 10 15 20 25 30 35
2000
2001
2003
2004
2005
2006
2007
2008
2009
2010
2011
2011
2012
2013
2014
2015
Sumber : diolah dr BPS 2015
Persentase Penduduk yang Menggunakan
Obat Tradisional (2000-2014)
0 5 10 15 20 25 30 35 40
1998
2000
2003
2005
2007
2009
2011
2013
Sumber : diolah dr BPS 2015
Definisi Herbal Medicine
Herbal Medicine merupakan bahan yang digunakanuntuk Pengobatan Tradisional (Traditional Medicine)
WHO mendefinisikan Traditional Medicine : It is the sum total of the knowledge, skills and practices based on the theories, beliefs and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health, as well as in the prevention, diagnosis, improvement or treatment of physical and mental illnesses
Other terms; complementary/alternative/non-conventional medicine
Traditional use of herbal medicines
Herbal medicines include herbs, herbal materials, herbal preparations and finished herbal products, that contain as active ingredients parts of plants, or other plant materials, or combinations.
Category Herbal Medicine by WHO;
Category 1: Indigenous herbal medicines
Category 2: Herbal medicines in systems
Category 3: Modified herbal medicines
Category 4: Imported products with a herbal medicine base
Why Herbal Medicine ? Jutaan penduduk di negara berkembang selalu
menggunakan ‘Herbal Medicine’ karena merekapercaya dan terlebih kerena merupakan ‘their system of medicine’
Mudah diperoleh, ketersediaan setiap waktu para‘Healer/ Dukun’, keyakinan akan bahan alam (natural thing) khususnya dipedesaan.
Harga yang murah dan terjangkau
Amankah Herbal Medicine ?
There is a widespread misconception that “natural” always means “safe”, and
A common belief that remedies from natural origin are harmless and carry no risk.
However, some medicinal plants are inherently toxic.
WHO established a minimum requirements for assessment of safety of herbal medicines:
Category 1: safety established by use over long time
Category 2: safe under specific conditions of use (such herbal medicines should preferably be covered by well-established documentation)
Category 3: herbal medicines of uncertain safety (the safety data required for this class of drugs will be identical to that of any new substance)
Usaha untuk Meningkatkan Safetydan Efficacy Penggunaan Herbal Koordinasi dan Harmonisasi masing-masing negara
dalam menghasilkan regulasi ttg Herbal Medicine.
Quality Assurance produk herbal seperti ; Implementasi Good Agricultural and Collection Practice (GACP), Good Manufacturing Practice (GMP), dll.
Farmacovigilance dan
Pengawasan iklan.
Penyusunan Monografi dan Farmakope Herbal.
Herbal Medicine di Indonesia
Perka BPOM RI No HK. 00.05.4.2411
Potensi Herbal Indonesia
1. Indonesia merupakan mega-centerkeanekaragaman hayati dunia (2nd in the world)
2. Memiliki 30.000 species tumbuhan dansekitar 9.600 diantaranya tumbuhanberkhasiat.
3. 300 spesies telah digunakan sebagaibahan obat tradisional (OT) oleh industriOT.
GLOBAL HERBAL MARKET INCL NUTRACEUTICALS
$ 70.4 BILLION
EXCLUSIVE GLOBAL HERBAL MARKET
$ 24.2 BILLION
GLOBAL SCENARIO
0
5
10
15
20
25
US
$
Bil
lio
n
Year
1994
Year
1997
Year
1999
Year
2002
Global Sales of Herbal Medicine
49%
31%
70%
10%
33%
49%42%
12.414.0
24.18
19.58
From CK Katiyar, 2006
Strategi Pengembangan Herbal Indonesia
From Dir. Bina Prod dan Distribusi Kefarmasian
From Dir. Bina Prod dan Distribusi Kefarmasian
Jenis Tumbuhan Obat yang Banyak Digunakan
From Gunawan, 2014
Industri Obat Tradisional di Indonesia
Form, Sido Muncul report, 2014
Form, Sido Muncul report, 2014
Jumlah Produk Teregistrasi pada BPOM
Form, Sido Muncul report, 2014
Potensi dan Pemanfaatan Tanaman Lokaldalam Herbal Medicine
Pegagan = Centella asiatica
Tahun Perkembangan Kegunaan
3000 yl Indian Ayurvedic Asma, bronchitis, dropsi, elepantiasis, lepra, ganggianginjal, leucorhoea, gangguan kulit, uretritis
2000 yl Chinese Shennong Herbal Leucorrhoe, fever
1884 French Pharmacopoeia
1983 British Herbal Pharmacopoeia
Kegunaan topikal: Ulser, wounds, sikatris stlh operasi
Etnobotanical Time-line
Tahun Nama Produk Negara
1968 TECA (Like Madecassol), Oitment 1% Portugal
1969 Madecassol, Krim 1%, tablet Belgia
1973 TECA, tablet Portugal
1974 TECA (Madecassol), Tablet Perancis
1975 TECA, Cream 1%, Powder 2% Perancis
1976 TECA, steril Perancis
1982 TECA (Centellase), Tablet Italy
1997 Bilim (like Madecassol), Oitment 1% Greece
Produk Development Time-line
Kandungan Senyawa Aktif pada Pegagan
Elephantopus scaber L.(Tapak Liman)
Kabeer and Prathapan, 2014
Kegunaan Tradisional
Kajian Bioaktivitas dan Farmakologi
Produk/ Sediaan Elephantopus scaber L.
PengembanganTumbuhan Obatdi Industri
From; Trade in Medicinal Plant, FAO-Rome, 2004
Added Value Phytomedicine
Daun Gambir
Ekstrak gambir
Ekstrak Terpurifikasi
Nano/Mikro katekin
Marker
Rp 800/kg
Rp 30-45 rb/kg
Rp 350-500 rb/ Kg
???
220 USD/ 25 mg
Uncaria gambier Robx