DAFTAR ISI

Lembar Pengesahan.............................................................................................i

Kata Pengantar....................................................................................................ii

BAB 1...................................................................................................................1

1.1 Latar Belakang.....................................................................................1

1.2 Kajian Masalah....................................................................................7

1.3 Rumusan Masalah...............................................................................8

1.4 Tujuan Penelitian................................................................................9

1.4.1 Tujuan Umum...........................................................................9

1.4.2 Tujuan Khusus..........................................................................9

1.5 Manfaat Penelitian............................................................................10

1.5.1 manfaat Teoritis.....................................................................10

1.5.2 manfaat praktis......................................................................10

BAB 2 Tinjauan Pustaka ....................................................................................11

2.1 Pembuluh Darah...............................................................................11

2.1.1 Anatomi Pembuluh Darah......................................................11

2.1.2 Arteri......................................................................................14

2.1.3 Vena.......................................................................................15

2.1.4 Mikrosirkulasi.........................................................................16

2.1.5 Kompliansi Arteri Vena...........................................................18

2.1.6 Sel Endotel..............................................................................18

2.2 Biji Labu Kuning.................................................................................23

2.2.1 Mengenal Tanaman Labu Kuning...........................................23

2.2.2 Komponen Kimia dalam Biji Labu Kuning...............................25

2.3 Arginin...............................................................................................26

2.3.1 Peran Arginin dalam Endotelium............................................31

2.3.2 Nitric Oxide/Nitrat Oxida (NO)...............................................32

2.3.3 Superoxide dismutase (SOD)..................................................36

BAB 3 Kerangka Konseptual..............................................................................38

3.1 Bagan Kerangka Konseptual..............................................................39

3.2 Penjelasan Kerangka Konseptual......................................................40

3.3 Hipotesis Penelitian...........................................................................40

BAB 4 Metode Penelitian..................................................................................41

4.1 Jenis dan Rancang Bangun Penelitian...............................................41

4.2 Lokasi dan Waktu Penelitian.............................................................41

4.2.1 Lokasi Penelitian.....................................................................41

4.2.2 Waktu Penelitian....................................................................42

4.3 Unit Eksperimen................................................................................42

4.4 Variabel Penelitian............................................................................43

4.4.1 Variabel Bebas........................................................................43

4.4.2 Variabel tergantung................................................................43

4.5 Definisi Operasional..........................................................................43

4.5.1 Biji Labu Kuning (Curcubita Peppo Seeds)..............................43

4.5.2 L-arginin, Nitric Oxide,Elastisitas Pembuluh Darah.................43

Daftar Pustaka...................................................................................................44