Sintesis Asam Lemak

Oleh kelompok 4Mochammad Febry Pratama

Ninda Ramadani Herli NSifa Fauziah Dwidara

terjadi di sitoplasma khususnya pada bagian hepar dan kelenjar adiposa

Sintesis asam lemak terjadi apabila kelebihan Asetil-KoA

Reaksi dimulai dgn membawa asetil KoA keluar dari mitokondria ke sitoplasma melalui torak sitrat (citrate shuttle)

torak sitrat (citrate shuttle)

Citrate Shuttle (regeneration of pyruvate)

Oxaloacetate is converted back to pyruvate for re-entry into mitochondria

Step 1 Oxaloacetate + NADH + H+ 1048774 malate + NAD+ Reverse of the TA cycle reaction Catalyzed by cytosolic malate dehydrogenase

Step 2 Malate + NADP+ 1048774 pyruvate + CO2 + NADPH Catalyzed by malic enzyme

Pyruvate translocase transports pyruvate into mitochondria Pyruvate is converted to oxaloacetate by pyruvate carboxylase with

coupled hydrolysis of one ATP Pyruvate + ATP + CO2 + H2Orarroxaloacetate + ADP + Pi (reaction of gluconeogenesis)

Net Reaction NADP+ + NADH + H+ + ATP + H2O 1048774 NADPH + NAD+ + ADP + Pi

Thus transport of acetylCoA to cytosol requires expense of one ATP and conversion of one NADH to NADPH

Reaksi ini terjadi dalam 4 tahap dengan pemanjangan 2 atom karbon yaitundash Condensationndash Reductionndash Dehydrationndash reduction

bull Reaksi ini membutuhkan NADPH (Reaksi Enzim Malat HMP ShuntReaksi TCA)

digunakan untuk sintesis sebagai reduktor

ATP untuk membentuk ikatan tioester pada asetil KoA dan menggabungkan CO2 pada asetil KoA menjadi malonil KoA

CO2

Pembentukan Malonyl-CoA

Reaksi ini katalisis oleh enzim Acetyl CoA Carboxylase (mengandung gugus prostetik biotin)yang diaktifkan oleh sitrat dan Insulin

Pemanjangan rantai

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

terjadi di sitoplasma khususnya pada bagian hepar dan kelenjar adiposa

Sintesis asam lemak terjadi apabila kelebihan Asetil-KoA

Reaksi dimulai dgn membawa asetil KoA keluar dari mitokondria ke sitoplasma melalui torak sitrat (citrate shuttle)

torak sitrat (citrate shuttle)

Citrate Shuttle (regeneration of pyruvate)

Oxaloacetate is converted back to pyruvate for re-entry into mitochondria

Step 1 Oxaloacetate + NADH + H+ 1048774 malate + NAD+ Reverse of the TA cycle reaction Catalyzed by cytosolic malate dehydrogenase

Step 2 Malate + NADP+ 1048774 pyruvate + CO2 + NADPH Catalyzed by malic enzyme

Pyruvate translocase transports pyruvate into mitochondria Pyruvate is converted to oxaloacetate by pyruvate carboxylase with

coupled hydrolysis of one ATP Pyruvate + ATP + CO2 + H2Orarroxaloacetate + ADP + Pi (reaction of gluconeogenesis)

Net Reaction NADP+ + NADH + H+ + ATP + H2O 1048774 NADPH + NAD+ + ADP + Pi

Thus transport of acetylCoA to cytosol requires expense of one ATP and conversion of one NADH to NADPH

Reaksi ini terjadi dalam 4 tahap dengan pemanjangan 2 atom karbon yaitundash Condensationndash Reductionndash Dehydrationndash reduction

bull Reaksi ini membutuhkan NADPH (Reaksi Enzim Malat HMP ShuntReaksi TCA)

digunakan untuk sintesis sebagai reduktor

ATP untuk membentuk ikatan tioester pada asetil KoA dan menggabungkan CO2 pada asetil KoA menjadi malonil KoA

CO2

Pembentukan Malonyl-CoA

Reaksi ini katalisis oleh enzim Acetyl CoA Carboxylase (mengandung gugus prostetik biotin)yang diaktifkan oleh sitrat dan Insulin

Pemanjangan rantai

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

torak sitrat (citrate shuttle)

Citrate Shuttle (regeneration of pyruvate)

Oxaloacetate is converted back to pyruvate for re-entry into mitochondria

Step 1 Oxaloacetate + NADH + H+ 1048774 malate + NAD+ Reverse of the TA cycle reaction Catalyzed by cytosolic malate dehydrogenase

Step 2 Malate + NADP+ 1048774 pyruvate + CO2 + NADPH Catalyzed by malic enzyme

Pyruvate translocase transports pyruvate into mitochondria Pyruvate is converted to oxaloacetate by pyruvate carboxylase with

coupled hydrolysis of one ATP Pyruvate + ATP + CO2 + H2Orarroxaloacetate + ADP + Pi (reaction of gluconeogenesis)

Net Reaction NADP+ + NADH + H+ + ATP + H2O 1048774 NADPH + NAD+ + ADP + Pi

Thus transport of acetylCoA to cytosol requires expense of one ATP and conversion of one NADH to NADPH

Reaksi ini terjadi dalam 4 tahap dengan pemanjangan 2 atom karbon yaitundash Condensationndash Reductionndash Dehydrationndash reduction

bull Reaksi ini membutuhkan NADPH (Reaksi Enzim Malat HMP ShuntReaksi TCA)

digunakan untuk sintesis sebagai reduktor

ATP untuk membentuk ikatan tioester pada asetil KoA dan menggabungkan CO2 pada asetil KoA menjadi malonil KoA

CO2

Pembentukan Malonyl-CoA

Reaksi ini katalisis oleh enzim Acetyl CoA Carboxylase (mengandung gugus prostetik biotin)yang diaktifkan oleh sitrat dan Insulin

Pemanjangan rantai

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Citrate Shuttle (regeneration of pyruvate)

Oxaloacetate is converted back to pyruvate for re-entry into mitochondria

Step 1 Oxaloacetate + NADH + H+ 1048774 malate + NAD+ Reverse of the TA cycle reaction Catalyzed by cytosolic malate dehydrogenase

Step 2 Malate + NADP+ 1048774 pyruvate + CO2 + NADPH Catalyzed by malic enzyme

Pyruvate translocase transports pyruvate into mitochondria Pyruvate is converted to oxaloacetate by pyruvate carboxylase with

coupled hydrolysis of one ATP Pyruvate + ATP + CO2 + H2Orarroxaloacetate + ADP + Pi (reaction of gluconeogenesis)

Net Reaction NADP+ + NADH + H+ + ATP + H2O 1048774 NADPH + NAD+ + ADP + Pi

Thus transport of acetylCoA to cytosol requires expense of one ATP and conversion of one NADH to NADPH

Reaksi ini terjadi dalam 4 tahap dengan pemanjangan 2 atom karbon yaitundash Condensationndash Reductionndash Dehydrationndash reduction

bull Reaksi ini membutuhkan NADPH (Reaksi Enzim Malat HMP ShuntReaksi TCA)

digunakan untuk sintesis sebagai reduktor

ATP untuk membentuk ikatan tioester pada asetil KoA dan menggabungkan CO2 pada asetil KoA menjadi malonil KoA

CO2

Pembentukan Malonyl-CoA

Reaksi ini katalisis oleh enzim Acetyl CoA Carboxylase (mengandung gugus prostetik biotin)yang diaktifkan oleh sitrat dan Insulin

Pemanjangan rantai

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Reaksi ini terjadi dalam 4 tahap dengan pemanjangan 2 atom karbon yaitundash Condensationndash Reductionndash Dehydrationndash reduction

bull Reaksi ini membutuhkan NADPH (Reaksi Enzim Malat HMP ShuntReaksi TCA)

digunakan untuk sintesis sebagai reduktor

ATP untuk membentuk ikatan tioester pada asetil KoA dan menggabungkan CO2 pada asetil KoA menjadi malonil KoA

CO2

Pembentukan Malonyl-CoA

Reaksi ini katalisis oleh enzim Acetyl CoA Carboxylase (mengandung gugus prostetik biotin)yang diaktifkan oleh sitrat dan Insulin

Pemanjangan rantai

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Pembentukan Malonyl-CoA

Reaksi ini katalisis oleh enzim Acetyl CoA Carboxylase (mengandung gugus prostetik biotin)yang diaktifkan oleh sitrat dan Insulin

Pemanjangan rantai

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Pemanjangan rantai

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Elongation of Palmitate to Stearoyl

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Sintesis asam lemak tak jenuh

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

bull The double bonds of palmitoleate and oleate are introduced in vertebrates by fatty acyl-CoA desaturase together with cytochrome b5 and cytochrome b5 reductase

bull Two substrates fatty acyl-CoA and NADPH are oxidized simultaneously by O2 The desaturase is thus a mixed-function oxidase

Desaturation of fatty acids

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Fatty acyl-CoA is desaturated (oxidized)

using O2 and NADPH(in smooth ER)

ER membrane

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

DIAGRAM OF SYNTHESIS

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Asam lemak essensial

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Asam Lemak essensialAsam lemak essensial tidak dapat

dihasilkan sendiri oleh tubuh karena tidak mempunyai enzim yang dapat menyisipkan ikatan ganda diluar posisi 9 di asam lemak jenuh

Asam lemak yang essensial bagi mamalia adalah asam lemak linoleat dan α-linolenat

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Sintesis asam lemak esensial

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Sintesis omega 3

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Fatty acid elongation and desaturase(s) systems act jointly in generation of long- and very-long-chain unsaturared fatty acids Starting from C16 and C18 elongation specific desaturases generate cis-monounsaturated palmitoleic acid (Δ9 C161) and oleic acid (Δ9 C181 Fig 1) Both palmitoleic and oleic acid are then used for the synthesis of a variety of other long-chain unsaturated fatty acids

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml

Animasihttpwwwwileycomcollegefobquizquiz1919-22htmlhttpwwwwileycomcollegepratt0471393878studentanimationsfatty_acidindexhtmlhttpbio-animationsblogspotcom200804biochemistry-fatty-acid-metabolismhtml