Post on 06-Apr-2018
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LSM2102 Molecular Biology
Regulation of Eukaryotic geneexpression
Adam Yuan
dbsyya@nus.edu.sgadam@tll.org.sg
mailto:dbsyya@nus.edu.sgmailto:dbsyya@nus.edu.sg8/3/2019 LSM2102-6
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Main textbook
Alberts et al. (2008) Molecular Biology of
Cell (5th Edition) or (4th Edition, 2002) Chapter 6, How cells read the genome:
from DNA to protein Chapter 7, Control of gene expression.
Chapter 22, Development of multicellularorganisms
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Argonaute structures
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The Nobel Prize in Physiology or Medicine 2006"for their discovery of RNA interference - gene silencing by double-stranded RNA"
Importance of RNA silencing
Andrew Z. Fire Craig C. Mello
RNAi occurs inplants, animals, and humans
Function:Gene expression regulationViral infections defense
Jumping gene control
Biotechnology Tools:Gene function studyNovel therapies in the future
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