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This article was downloaded by: [University of Oslo], [anita tørmoen]On: 20 May 2014, At: 23:29Publisher: RoutledgeInforma Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House,37-41 Mortimer Street, London W1T 3JH, UK

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Feasibility of Dialectical Behavior Therapy with Suicidaland Self-Harming Adolescents with Multi-Problems:Training, Adherence and RetentionA. J. Tørmoen a , B. Grøholt b , E. Haga a , A. Brager-Larsen c , A. Miller d , F. Walby a f , B.Stanley e & L. Mehlum aa National Centre for Suicide research and Prevention, Institute of Clinical Medicine,University of Oslo , Norwayb Institute of Clinical Medicine, University of Oslo , Norwayc Department of Child and Adolescent Mental Health , Oslo University Hospital, Division ofMental Health and Addiction , Oslo South/North , Norwayd Montefiore Medical Center, Child Outpatient Psychiatry , New York , USAe New York State Psychiatric Institute, Columbia University , New York , USAf Department of Psychiatry , Diakonhjemmet Hospital , Oslo , NorwayAccepted author version posted online: 19 May 2014.Published online: 19 May 2014.

To cite this article: A. J. Tørmoen , B. Grøholt , E. Haga , A. Brager-Larsen , A. Miller , F. Walby , B. Stanley & L. Mehlum(2014): Feasibility of Dialectical Behavior Therapy with Suicidal and Self-Harming Adolescents with Multi-Problems: Training,Adherence and Retention, Archives of Suicide Research, DOI: 10.1080/13811118.2013.826156

To link to this article: http://dx.doi.org/10.1080/13811118.2013.826156

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Feasibility of Dialectical Behavior Therapy with Suicidal and Self-harming Adolescents with Multi-problems: Training, Adherence and Retention

A. J. Tørmoen1, B. Grøholt2, E. Haga1, A. Brager-Larsen3, A. Miller4, F. Walby1,6, B.

Stanley5, L. Mehlum1

1National Centre for Suicide research and Prevention, Institute of Clinical Medicine, University of Oslo, Norway, 2Institute of Clinical Medicine, University of Oslo, Norway, 3Department of Child and Adolescent Mental Health, Oslo University Hospital, Division

of Mental Health and Addiction, Oslo South/North, Norway, 4Montefiore Medical Center, Child Outpatient Psychiatry, New York, USA, 5New York State Psychiatric

Institute, Columbia University, New York, USA, 6Department of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway

Corresponding author: Anita Johanna Tørmoen, Ph.D. candidate , E-mail :

[email protected]

KEYWORDS: Suicidal behavior, self-harm, psychotherapy, adolescents, treatment

INTRODUCTION

Self-harm among adolescents is a complicated behaviour to treat. Clinical samples of

self-harming adolescents are frequently characterized by affective instability, strong

emotional reactivity and impulsivity (Jacobson et al., 2008; Joiner, Jr. et al., 2005;

Jacobson & Gould, 2007; Nock, 2010; Crowell et al., 2009), and treatment rejection,

drop-out or frequent therapist changes preclude the receipt or completion of treatment

(Trautman et al., 1993; Miller et al., 2007). Self-harm is associated with recurrent

psychosocial problems (Jacobson et al., 2008; Jacobson & Gould, 2007; Tormoen et al.,

2012) and poor long-term outcome (Groholt & Ekeberg, 2009a; Fergusson & Lynskey,

1995). Features of Borderline Personality Disorder (BPD) are often found in adolescents

who self-harm, but BPD is rarely diagnosed in adolescence, even though research has

shown that it may be a valid and reliable diagnosis for this age group (Miller et al., 2008;

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Chanen et al., 2007). Symptoms of BPD in adolescents are related to having other

psychiatric symptoms and functional impairment (Chanen et al., 2007), and are also

found to have negative long term consequences (Winograd et al., 2008). Given the

problems of emotional dysregulation in both self-harming adolescents and BPD patients,

the prevalence of BPD symptoms among adolescents who self-harm, as well as the long

term consequences associated with these symptoms, interventions targeting these

populations are needed. The extent of comorbidity within this patient group makes

adhering to any single traditional treatment protocol problematic, and in fact, traditional

treatments in the cognitive-behavioral spectrum show impaired effectiveness for clients

with personality disorders and self-harm behavior (Steiger & Stotland, 1996; Hazell et

al., 2009; Linehan et al., 1991; Linehan, 1993). One notable exception, is a specialized

treatment program of mentalization-based treatment for adolescents (MBT-A). MBT-A

was found to be superior to TAU in reducing self-harm and depression (Rossouw &

Fonagy, 2012). No other treatment program specially targeting self-harm in adolescents

has so far been shown to reduce self-harm more than usual care, but one study found that

both cognitive analytic therapy and manualized clinical good care equally both reduced

parasuicide (Chanen et al., 2008)

In spite of the seriousness of self-harm, there still is a paucity of empirically supported

treatments targeting self-harm behavior in adolescents. In fact, outpatient treatment

effectiveness studies have often excluded adolescents with self-harm and suicidal

behaviors. Numerous randomized controlled trials have now established Dialectical

Behavior Therapy (DBT) with adults as the most effective treatment for patients with

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Borderline Personality Disorder, repetitive self-harm and suicidal behavior (Linehan et

al., 1994; Linehan et al., 2006; Linehan et al., 1993; Verheul et al., 2003; Koons et al.,

2001; Crowell et al., 2009; Van Den Bosch et al., 2005). DBT was designed to accurately

and effectively target the core symptoms of emotional dysregulation and its subsequent

cognitive, behavioral, self, and interpersonal sequelae.

Adaptations of DBT for adolescents has been developed and provided in various settings

and with various patient groups within which emotional dysregulation is a core symptom

(James et al., 2008; Katz et al., 2004; McDonell et al., 2010; Rathus & Miller, 2002;

Salbach-Andrae et al., 2008; Woodberry & Popenoe, 2008; Fleischhaker et al., 2011;

Goldstein et al., 2007). These treatments all had major deviations from the original

model for adults, considerable variability regarding populations, variability in

descriptions of how and if they adhered to the original DBT protocol, as well as variation

in the structure and format of the treatment. Hence, a recent literature review on DBT for

adolescents concludes that studies with clear descriptions of the intervention, with

intensively trained and adherent therapists are needed (Groves et al., 2012). To date, no

randomized controlled studies (RCT) of DBT for adolescents have been published in a

peer reviewed journal. The present study represents the first research on DBT for

adolescents in Scandinavia. To our knowledge, this is the first study reporting on

feasibility and adherence evaluated by a trained adherence coder documenting adherent

DBT for adolescents.

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The aims of this study were to evaluate feasibility and acceptability of the DBT

treatment approach for adolescents Specifically, the aims were to determine: 1) if

therapists could effectively learn and provide adherent DBT for adolescents, 2) whether

treatment retention among adolescents was possible to achieve in a 16-week DBT

program, 3) if self-harm behavior decreased among those who completed treatment, and

4) if the improvement of those who completed treatment endured over a one year follow

up period.

METHODS

Participants

Participants were 27 adolescents with repeated self-harm behavior recruited from five

child and adolescent psychiatric outpatient clinics in Norway. Inclusion criteria were: 1)

age between 12 and 18 years, 2) more than one lifetime episode of self-harm with one of

the episodes within the last 4 months before referral, 3) three or more criteria of DSM-IV

Borderline Personality disorder, 4) willingness to receive DBT, and 5) ability to speak

Norwegian. Self-harm behavior was defined as an act with a nonfatal outcome in which

the person deliberately engaged in behavior intended to cause harm, such as cutting,

jumping from heights, overdosing or eating non digestible objects (Hawton et al., 2002),

and thus includes both suicidal and nonsuicidal self-harm. Exclusion criteria were 1)

mental retardation, 2) an autism spectrum disorder, 3) psychotic disorder or 4) severe

anorexia nervosa or severe substance abuse disorder requiring specialised treatment. The

clinics screened patients who were newly referred for treatment for current and past

history of self-harm behavior. If screened positively, the patient and the parents were

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invited to a diagnostic interview where the remaining inclusion criteria were checked. A

few additional patients with self-harming behavior were already in other treatment, and,

were transferred to DBT by their therapists after having consulted with the patients and

their parents. Altogether thirty-seven consecutively referred adolescents were evaluated

for inclusion and of these, 27 (73%) fulfilled inclusion criteria and provided both patient

and parental consent to study participation. Seven of the ten who were not included, did

not fulfil the inclusion criteria, and six declined after having been oriented about DBT

comprising both individual therapy and skills group sessions with parents. Three patients

were referred to other treatment because they met exclusion criteria of mental retardation

or psychotic disorder. The study was approved by the Regional Committees for Medical

and Health Research Ethics in South Eastern Norway. Therapy was provided at no cost

to the families, within the framework of the health care system in Norway.

Assessments

Participants were assessed at baseline with structured interviews and self-report

instruments, weekly during the treatment period with self-report instruments and again at

follow up one year after treatment completion with structured telephone interviews.

Interviews were conducted by master’s or doctoral level clinicians trained in the use of

the assessment instruments.

Instruments

DSM-IV Axis I diagnoses were made by the semi-structured Schedule for Affective

Disorders and Schizophrenia, child version (K-SADS) (Kaufman et al., 1997). History of

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psychiatric treatment was also assessed according to the K-SADS interview. The

Structured Clinical Interview for DSM IV for Axis II disorders, Borderline Personality

Module (First, 1997) was used to diagnose Borderline Personality Disorder.

Self-harm was assessed by the structured interview Lifetime Parasuicide Count (LPC)

(Linehan & Comtois, 1996). Self-reported actions and urges to self-harm, at the start and

at the end of the 16 weeks course of DBT, were collected by standard DBT for

adolescents diary cards. They provide self-reported scores on a 5-point scale on a

number of measures related to self-harm, suicidality and feelings. The mean scores

reported during the first two and last two weeks of treatment were compared.

The number of psychiatric hospitalizations during treatment was reported by the

individual therapist for each patient. Since no one had more than one inpatient stay

during treatment, data were categorized into yes or no. Treatment retention was defined

by no more than three absences either in individual therapy or in skills-group and others

were considered as drop-outs. Information on self-harm at follow up was gathered during

a structured telephone interview done by the first author by asking the question “have you

self-harmed in the period since you ended DBT treatment?”

Adherence

Therapists were instructed to tape all sessions and deliver tapes consecutively for

adherence coding. They were not told how many or which of the tapes that would be

coded. A coder trained to reliability by the Linehan Research and Therapy Clinic,

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assessed the therapists' adherence to DBT principles by coding videotaped individual

therapy sessions and skills group sessions using the DBT global rating scale, a 66-item

adherence coding instrument (Linehan & Korslund, 2003). The items are grouped into

categories that follow the treatment components and scores range from 0-5. Altogether 37

treatment sessions were coded. Four of these sessions were multifamily skills groups, as

adherence coding in the course of the on-going development of adherence coding systems

for adolescent skills training groups was a part of the implementation process.

Therapists

Sixteen therapists consisting of clinical psychologists, one educational psychologist and

psychiatrists with experience up to twentyfive years of prior clinical experience

delivering other forms of psychotherapy were recruited. All the therapists were new to

DBT and were trained for the purpose of the study by trainers from the Behavioral Tech,

LLC. After being trained, eleven of the therapists were selected by the principal

investigator to become study therapists based on willingness to commit to both DBT and

the study or adherence coding results. Therapists were organized in two DBT

consultation team, based on their employment in two separate hospitals. Teams held

separate consultation team meetings weekly and received expert supervision from the

DBT trainers throughout the study. Clinicians were additionally trained in suicide risk

assessment and management for the purpose of the study.

Treatment

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DBT is a principle driven, partly manual based treatment, designed for the treatment of

adults with BPD. As its core, cognitive and behavioral change techniques are employed

within an acceptance-based framework. It contains strategies for reducing self-harm,

therapy interfering behaviors and quality of life interfering behaviors, as well as

strategies to increase the use of life skills that are compatible with a life worth living. The

primary focus in the first phase of DBT is stabilizing the patient and achieving behavioral

control by directly targeting self-harm behaviors as a first priority, dealing with behaviors

that interfere with treatment secondly, and then targeting behaviors that interfere in the

adolescent’s quality of life (e.g., depression, school problems, relationship difficulties). In

this study, a version adapted specifically for adolescents by Rathus and Miller (Rathus &

Miller, 2002), comprising all modalities and treatment protocols from the adult standard

DBT version was used. The adolescent version of DBT has a reduced duration (16 weeks

vs. 52 weeks in standard DBT) and consists of the following elements: one hour of

individual therapy per week, one weekly 2 hour multifamily skills training group, family

therapy sessions as needed, and inter-session telephone coaching in skills use as needed;

this was available on a 24-hour basis 7 days every week. Therapists met weekly for DBT

consultation team meetings. The modalities of the treatment serve five functions;

increasing behavioral capabilities, improving motivation, ensuring generalisation of skills

to the natural environment, structuring the treatment environment (i.e. interacting with

people in the environment to ensure that the client is not being reinforced for maladaptive

behaviors or punished for effective behaviors), and enhancing therapists’ ability and

motivation to treat patients effectively. Hand-outs and other materials adapted for

adolescents were translated from the original adolescent version (Miller et al., 2006) into

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Norwegian. The DBT program was provided in five child and adolescent psychiatric

outpatient clinics that participated in the study, all of which belonged to two hospitals in

Oslo. All treatments were conducted and funded by the two hospitals. DBT was the only

psychotherapeutic intervention given during the 16 weeks, but ancillary treatment, like

medication or hospital admissions was provided as needed and is described in the results

section.

Data Analysis

Descriptive data included baseline diagnoses, sociodemographics, global functioning,

previous psychiatric treatment and history of self-harm. Differences between completers

and drop outs were not tested because the small sample size would preclude the finding

of possible statistical differences. Only completers were included in statistical analyses.

McNemar chi square test for categorical data was used to assess change in the number of

patients who self-harmed during the first two weeks of treatment compared with the last

two weeks of treatment. Paired samples t tests were used to assess changes in scores on

continuous variables. SPSS Statistics version 17.0 was used.

Missing Data

Filling in diary cards and attending to them in the sessions was an integral part of the

treatment tool. Despite that diary card data were not collected for the purpose of research,

they nevertheless contained important information and were thus utilized in this study.

From each patient a mean number of 13 diary cards (SD 8.6) were available.

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In two cases of missing data, therapists were asked to provide informations regarding

patients’ non-suicidal self-harm based on the case-notes. Urges to self-harm, divided into

urges to engage in nonsuicidal self-harm and urges to attempt suicide were not always

reported in a readable manner on the diary card, thus reducing the number of patients

with available data on these variables to 14. At one year follow up we were able to trace

10 of 21 participants after two attempts to contact them (the maximum number of times

we were allowed by the ethics committee to attempt to make such contact with the

participants. We do not know if it was change of phone number, change of address, a

matter of bad timing, or other reasons that prevented us to trace the 11 patients who we

were unable to reach. All who were reached, however, agreed to be interviewed.

RESULTS

Total Sample Description

The mean age of the sample of 27 patients was 15.7 years (range 12-18, SD = 1.4) at the

start of treatment. The participants were 26 females and one male and predominantly of

Norwegian ethnicity (85%).

Of the 27 participating adolescents, 21(78%) completed the entire treatment. Six patients

were regarded as drop outs. Two of the dropouts, however, completed more than 50% of

the treatment, whereas 4 dropped out early in the treatment. Diagnostic and other

characteristics of the completers and dropouts are shown in Table 1. Of the whole

sample, eighteen patients (67%) had a primary diagnosis of Mood Disorder (10 with

Major Depressive Disorder, 6 with Mood Disorder not otherwise specified, 2 with

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Dysthymic Disorder). The remaining participants had either ADHD (n=1), panic

disorder without agoraphobia (n=1) substance dependence in early partial remission

(n=1), or no diagnosable axis I disorder (n=6). Forty-four percent of the patients fulfilled

5 or more criteria for BPD. Sixty-four percent had a history of suicide attempt(s) and

19% had received previous inpatient psychiatric treatment.

Adherence

Thirty-seven therapy sessions were coded and scored for adherence to DBT treatment

principles. The mean adherence score was 4.0 (range 3.5-4.2, SD 0.2), which qualifies as

adherent as scores of 4.0 or more indicate adherent sessions. Nearly 60 % of the coded

sessions were adherent. The majority of the non-adherent scores were just sub-threshold

4.0 (data not shown).

Baseline And Completers’ Scores On Repeated Measures

All patients had a history of repeated nonsuicidal self-harm in the four months before

inclusion in the trial. Sixty percent reported more than 20 lifetime episodes of nonsuicidal

self-harm. As shown in table 1 at baseline only two of the treatment completers did not

fulfil the criteria for at least one Axis I disorder. Of the patients with Axis I disorders, 6

had more than one disorder. Twelve of the treatment completers had a history of one or

more suicide attempts at baseline. The proportion of patients who had at least one episode

of nonsuicidal self-harm during the first two weeks of the treatment was compared with

the corresponding proportion during the last two weeks. Whereas 43% of the patients

reported nonsuicidal self-harm behavior during the first two weeks of treatment, only

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14% reported such behavior during the last two weeks. Urges of nonsuicidal self-harm

and suicide attempts were assessed through diary cards. For most patients, a substantial

decrease was observed during the course of treatment in mean scores of urges, for both

nonsuicidal self-harm and suicide attempts.

Differences Between Completers And Drop Outs

As shown in table 1 only one out of six dropouts had a mood disorder vs. 81% of the

completers. Four of the six dropouts did not fill criteria for any Axis 1 disorder compared

to two of the 21 completers. Two of those without any axis I disorder dropped out in the

first two weeks. None of the dropouts fulfilled five or more BPD criteria at baseline.

Thus, it appears that the dropouts had less severe psychiatric problems. Whereas

comparable fractions of the dropout and completer groups had a history of suicide

attempts, a higher percentage of the dropouts (67% vs 43%) reported more than 100

lifetime episodes of nonsuicidal self-harm.

Medication, Hospitalization And Suicide Attempts

One of the treatment completers used psychopharmacological medication during the

treatment period. Three of the completers had had a brief (1-2 days) psychiatric hospital

stay during the treatment period. The hospitalizations were due to single episodes of

attempted suicide with low medical seriousness and no need for somatic intervention.

Follow-Up

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Of the ten patients who were contacted by telephone one year after treatment completion,

seven reported no self-harm in the prior year. They were asked whether they had self-

harmed during the year after having participated in the DBT program.

DISCUSSION

This is the first study to report data on feasibility of implementing DBT for adolescents in

Scandinavia and also the first to report on adherence coding in DBT for adolescents. The

results indicate that DBT for adolescents can indeed be effectively implemented in a

Scandinavian culture and language context and health care system which differs

somewhat from the one in which DBT was developed. Therapists reached adequate

adherence levels, the treatment retention among the adolescents was high, and reductions

in episodes of and urges to self-harm were observed.

Reporting of treatment adherence levels are important to demonstrate the extent to which

the intervention have been delivered according to the treatment developers’ intentions, in

this case the DBT adaptation for adolescents developed and described by Miller and

colleagues (Miller et al., 2007). In this feasibility study, therapists with substantial

clinical experience, but who were new to DBT, were trained through a standard intensive

training program in DBT. Our adherence coding results, which are comparable to the

ones attained for standard DBT by the Linehan group (Linehan et al., 2006), indicate that

they were able to reach adequate levels of adherence rapidly, which is particularly

important when considering the feasibility of implementing such a novel treatment. We

recognize that the procedure of adherence coding and adherence feedback as a part of the

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study may have speeded up the learning process for therapists. Thus, this implementation

study is not totally comparable to clinical implementation per se, where therapists not

always use adherence coding as a part of their consultation to develop their skills as DBT

therapists. Some critics have argued that DBT is a very resource-demanding treatment to

implement. As far as adherence is concerned, this study shows that experienced non-

behavioral therapists can successfully learn, provide, and adhere to the treatment within a

relatively short time-frame.

Adolescents with self-harming behavior typically have a high treatment dropout rate (

67%) (Gould et al., 2003). In the present study, the retention rate was higher (78%), and

comparable to (Rathus & Miller, 2002; Fleischhaker et al., 2011) or higher than

(Woodberry & Popenoe, 2008) rates in other feasibility studies that used similarly

adapted versions of DBT. We do not have comparable studies of retention rate among the

Norwegian population of self-harming adolescents, but a Norwegian study of adolescent

suicide attempters showed that in spite of a large number referred to treatment, there was

low compliance to treatment after the suicide attempt. (Groholt & Ekeberg, 2009b)Our

high retention rate suggests that DBT for adolescents may have an advantage over other

treatments in its ability to keep patients in treatment. Keeping patients in treatment is an

explicit goal of DBT, and the use of motivational strategies and strategies to obtain

patients’ commitment to treatment, may have facilitated the high rate of treatment

completion. It could also be that the shortened duration of the treatment is particularly

appealing to adolescents, as one year can be a long time for adolescents and it may

require too much commitment. However, in a small study providing the one year

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standard DBT to older adolescents (16.4 years) 14 of the 16 participants completed the

whole year, suggesting that the treatment duration could be of less importance than

previously believed, at least for older adolescents (James et al., 2008). The six subjects

who dropped out of our study had fewer diagnosable Axis I disorders, and none of them

fulfilled the full criteria for BPD. This suggests that they may have had lower levels of

distress and lower psychiatric symptom levels and thus may not have felt a strong need

for such a comprehensive treatment program. DBT was originally developed for BPD

patients, and the treatment may thus not necessarily be perceived as equally relevant for

non BPD patients.

A decrease in self-harm behaviors was observed. A substantial number of participants

reported no self-harm behavior already within the first two weeks of treatment, although

they had all reported repeated self-harm within the last 4 months. Only a few of the

patients reported episodes of self-harm within the last two weeks of treatment. This is in

line with another study using a similar adaptation of DBT for adolescents (Fleischhaker

et al., 2011) and in studies of standard DBT (Linehan et al., 2006; Stanley et al., 2007).

Although our study was not designed to give information on treatment effects (DBT vs

standard treatment) or effect sizes, our observations suggest that DBT adapted for

adolescents could lead to early reduction in self-harm behavior.

This assumption is supported by the finding that whereas most of the patients in our

study reported high levels in the urge to self-harm (mean score 3.9) at the start of the

treatment, these scores decreased statistically and clinically significantly (to 1.8) towards

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the end of the treatment. After 14 weeks, only a few participants still had high scores on

urges to self-harm.

The present study cannot make any firm conclusions about why the changes in self-harm

behavior occurred. However according to the DBT treatment target hierarchy, self-harm

is considered the primary target behavior to decrease as long as it is present. It is

therefore likely that directly targeting this behavior increases the likelihood of gaining

control over it.

The observed reductions in self-harm behaviour were stable for seven of the ten patients

who were interviewed in the one year follow-up. We cannot exclude the possibility that

the ten patients traced may represent a positive selection with respect to treatment

outcome and function level even though we had no information indicating that such a

selection bias was present. Our results, in spite of any possible bias, are promising, and in

line with findings from a one year follow up on the German version of the DBT program

for adolescents in which the reduction of suicidal and nonsuicidal self-harm was found to

be stable over the course of one year (Fleischhaker et al., 2011).

Clinical Implications

Twelve clinical studies have reported on DBT for adolescents over the last decade, but

none of these have reported on adherence to the DBT adherence protocol. The present

study therefore adds to the literature by describing the feasibility and acceptability of a

clearly defined adaption of adherent DBT. Comparing the existing studies is difficult due

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to variability in their use of populations, settings and the actual DBT programs. In spite

of this, there is a common finding, among the existing studies, that adolescents treated

with DBT show improvements on a variety of measures of functioning (Groves et al.,

2012). Since none of these studies were designed as efficacy studies, there is now a

strong need for randomized controlled trials (Groves et al., 2012).

Study Strengths And Limitations

Our study adopted a complete DBT program adapted to adolescents according to Miller

and Rathus’ manual (Miller et al., 2006) and published book (Miller et al., 2007) and in

conjunction with the treatment developer. The adaptation included all the modalities that

are included in adult DBT. Among study strengths was the use of independent and

specifically trained evaluators. A major strength was also the use of a systematic

instrument for coding of therapists’ adherence to DBT treatment principles – this

instrument was applied by a coder trained to reliability with the treatment developer.

This aspect of the study provided useful information on the quality level of the treatment

delivered and served to improve the construct validity in this study. Such documentation

was pointed out as a major lack in earlier studies in a recent review of DBT for

adolescents by Groves and coworkers (2012) who suggest that reporting on adherence

should be implemented in future research.

Several limitations of this study should be noted. We did not include a control group or

follow up on those who dropped out of DBT, and thus conclusions about treatment

effects cannot be drawn. Without these data, we do not know if the changes reported are

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due to maturation, clinical instability, medication, placebo, selection bias, or other

effects. The study included baseline information of the whole sample, but only the

completers were followed up regarding the target behaviors, hence we have valid data

only for those who were able to complete the treatment. The acceptability of DBT in the

broader clinical population of adolescents is not described, as we have no information

about how many, if any, who declined to meet for an initial diagnostic interview.

Additionally, follow-up data were limited as they were based on telephone interviews

conducted by a non-independent and non-blinded interviewer.- This may have had

impact on the adolescents answers regarding such a sensitive topic as self-harm over

telephone. Follow up data are also limited because we only interviewed 10 of the

treatment completers. Conclusions about sustainable changes, therefore, cannot be drawn.

Despite the limitations, and in line with the purpose of the feasibility study, we conclude

that DBT for adolescents may be successfully implemented in Scandinavian outpatient

clinics and that clinicians seem to be able to learn and provide adherent DBT relatively

fast. The finding of such positive outcomes related to adherence, retention and reduction

of self-harm is understood as an indicator of acceptability for clinicians, adolescents and

families.

Implications For Future Research

To evaluate the efficacy of DBT with adolescents, a large scale randomized controlled

trial is required, and the first large RCT on DBT with adolescents is currently conducted

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at the National Centre for Suicide Research and Prevention in Norway. Thus, future

research on DBT for adolescents should advance from clinical observational studies such

as the present to efficacy or effectiveness studies. More studies evaluating the

sustainability of reduction in self-harm found during treatment are needed, and

evaluations of the importance of the length of treatment are recommended. Future

directions include examining what factors are of importance in improvement of treatment

adherence as well as the predictors of treatment retention and dropout.

CONCLUSIONS

We conclude that therapists were able to learn and adhere to DBT treatment principles

within a reasonable amount of time and deliver the treatment in a manner well received

by adolescents and their families. The clear reduction in the proportion of adolescents

who engaged in self-harm behavior yields sufficient support for this treatment program to

be tested in a larger RCT. In the developmental stage of adolescence, shortened versions

of effective treatments that are in line with their developmental needs seem to be a

sensible approach. Early reduction of self-harm could speed up the process of recovery

and make possible other therapeutic targets to be addressed, such as decreasing

symptoms of distress and increasing the use of coping strategies associated with a good

quality of life. If treatment effects can be gained relatively quickly, other follow up

treatment could focus on consolidation of gains.

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Table 1. Patients receiving DBT (N=27). Sample characteristics prior to treatment

Baseline characteristics

Measure Total N=27 Completers

N=21

Dropouts N=6

Age, median (SD) 15.7(1.4) 15.7(1.4) 16.0 (1.8)

Female, % (n) 96(26) 95(20) 100(6)

Norwegian ethnicity, % (n) 85(23) 81(17) 100(6)

Any primary mood disorder, % (n) 67(18) 81(17) 17(1)

Any other primary Axis I disorder,

%(n)

11(3) 10(2) 17(1)

Fulfilled 5 or more BPD criteria , % (n) 44(12) 57(12) 0

CGAS, Mean (SD) 61(12) 61(12) 60(10)

Previous outpatient psychiatric

treatment, % (n)

41(11) 38(8) 50(3)

Previous inpatient psychiatric

treatment, % (n)

19(5) 19(4) 17(1)

Previous psychopharmacological

treatment, % (n)

19(5) 19(4) 17(1)

Lifetime history of suicide attempts, %

(n)

64(16) 63(12) 67(4)

Number of lifetime episodes of NSSH

prior to treatment,% (n)

2-20 33(9) 38(8) 17(1)

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21-100 19(5) 19(4) 17(1)

>100 48(13) 43(9) 67(4)

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Table 2. Course of symptoms among completers

Self-harm and urges to self-harm during the treatment period

NSSH, %(n) N=21 completers 250a

First 2 weeks (1-2) 43(9)

Last 2 weeks (15-16) 14(3)

Urges to NSSH,mean (SD) N=14 3.80b*

First 2 weeks (1-2) 3.9(0.7)

Last 2 weeks (15-16) 1.8(1.8)

Urges to suicide attempts, mean (SD)

N=14

1.91b

First 2 weeks (1-2) 2.2(1.9)

Last 2 weeks (15-16) 1.1(1.7)

aMcNemar test for categorical variables (changes in percentage of study subjects

engaging in NSSH during the treatment period)

bPaired t-test for continuous variables (changes in mean score of urges to NSSH and

suicide attempt)

*p<0.01

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