SIALOGOGUE AND ANTI-

SIALOGOGUE

DR.FOYSAL SIRAZEE

BDS(DU),MS(FINAL PART),

BSMMU,DHAKA.

SIALOGOGUE

#Definition………….. Sialogogue are the

agents or drugs which are used to increased salivation due to dryness of mouth or any other reasons.

Classification of sialogogue

## sialogogue

Agent which increase

salivary reflex… *Bitter food

*Hot food

*Spicy food

*Alcohol

Saliva substitute *Anti-bacterial agent

*Complex mixture of salt

*Sorbitol or sweetener

*Cellulose and

* Flavoring agent

Cholino-mimetic drugs *Pilocarpin

*Neostigmine

*Physostigmine

HOT AND SPICY FOOD

SOUR FOODS

BITTER FOODS

Sialogogues agents

XEROSTOMIA

#Definition….. The term xerostomia or

“dry mouth” refers to a subjective complaint of dryness involving the oral mucosa and oro-pharynx that may or may not be accompanied by salivary gland hypo function, an objective decrease in salivary flow.

Etiologic factors/Causes of

xerostomia Potential etiologic factors for

Xerostomia and/or Salivary gland Hypo function……. #Mediations------ *Antihistamines *Decongestants *Antidepressants *Sedatives/ anxiolytic agent *Anti-hypertensive

agent *Anti-cholinergic agent *Anti- neoplastic agent *Anti-psychotic agent #Radiation therapy

Etiologic factors/Causes of

xerostomia…..continue

#Systemic diseases-----

*Sjögren’s syndrome

*Diabetes mellitus

*Diabetes insipidus

*Sarcoidosis

*Human Immunodeficiency Virus

*(HIV) infection

*Hepatitis C infection

*Graft versus host disease

*Parkinson’s disease