3b2b_cup_doh_4_s2_fmi 1..1 - Cambridge University Press

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8th World Congress on Developmental Origins of Health and Disease, 17-20 November 2013, SUNTEC Singapore Supported by: Held in: https://doi.org/10.1017/S2040174413000433 Downloaded from https://www.cambridge.org/core. IP address: 65.21.229.84, on 10 Jan 2022 at 11:24:22, subject to the Cambridge Core terms of use, available at https://www.cambridge.org/core/terms.

Transcript of 3b2b_cup_doh_4_s2_fmi 1..1 - Cambridge University Press

8th World Congress on Developmental Origins of Healthand Disease, 17-20 November 2013, SUNTEC Singapore

Supported by:

Held in:

https://doi.org/10.1017/S2040174413000433Downloaded from https://www.cambridge.org/core. IP address: 65.21.229.84, on 10 Jan 2022 at 11:24:22, subject to the Cambridge Core terms of use, available at https://www.cambridge.org/core/terms.

Table of Contents

Agricultural applications

Identification of micrornas of the mammary gland associated with milk production of dairy cowsDOHaD13-1362 S51

Kuljeet Singh, Paul H Maclean, Regan Murney, Kim Oden, Kerst Stelwagen

Milk leptin and IGF1 in early lactating sows according to body composition and mammarygland position

DOHaD13-1319 S51

Latifa Abdennebi-Najar, Marie Daupley, Samir DOU, Jean Yves Madec, Claude-Narcisse NIAMBA,Duane H Keisler

Animal models of programming

A macaque model of IUGR shows investment in bone and brain only on a high fat dietDOHaD13-1252 S51

Ai Ling Teh, Louiza Chan, Yong Chee Tan, Pei Fang Tan, Christopher Yeung, Melvir Singh, Johnny Wong,Peter Gluckman, Joanna Holbrook, Michael Meaney, Keefe Chng

A murine model for maternal smoking to study the role of micrornas in transgenerational asthmatransmission

DOHaD13-1394 S52

Stefan Dehmel, Petra Nathan, Katrin Milger, Raphael Prungnaud, Rabea Imker, Martin Irmler, JohannesBeckers, Oliver Eickelberg, Susanne Krauss-Etschmann

A novel model for retinopathy of prematurity: effects in adult mice after neonatal exposure tohyperoxic gas

DOHaD13-1384 S53

Sheena Bouch, Xiangting Chen, Foula Sozo, Richard Harding, Paul McMenamin

An animal model of low grade chronic inflammation and prenatal programming of offspring diseaseDOHaD13-1420 S53

Anete Dudele, Tobias Wang, Sten Lund

An animal model of paternal obesity programs metabolic disturbances in two generations of miceand alters the transcriptional profile of founder testis and sperm microrna content

DOHaD13-1659 S54

Tod Fullston, Nicole O. McPherson, Julie A. Owens, Michelle Lane

Animal models and fetal programming: an integrative literature approachDOHaD13-1667 S54

Narges Bahi-Jaber, Andreı Mogoutov, Ghada Elmhiri, Latifa Abdennebi-Najar

Antigen Capture Therapy (ACT) for the prevention of intrauterine inflammation, fetal injury andpreterm birth

DOHaD13-1042 S55

Matthew Kemp, Masatoshi Saito, Matthew Payne, Demelza Ireland, Suhas Kallapur, Alan Jobe, BorisKramer, Yuichro Miura, John Newnham, Jeffrey Keelan

Early weaning in rats modifies glucagon-like peptide 1 (GLP 1) profile contributing to the obesitydevelopment in adult life

DOHaD13-1173 S55

Elaine Oliveira, Patricia C. Lisboa, Fernanda T. Quitete, Jessica L. Nobre, Egberto G. Moura

Effect of low dose intra-amniotic endotoxin on kidney development in ratsDOHaD13-1330 S56

Keiji Suzuki, Hidehiro D. Takahashi

Effect of vitamin D deficiency on skeletal development across the early lifecourseDOHaD13-1704 S57

Tsiloon Li, Stuart A. Lanham, Philipp J. Thurner, Richard O. Oreffo

Effects of experimental hyperleptinaemia in neonatal rats on subsequent sucrose preference andreward-related receptor density

DOHaD13-1726 S57

Tim South, Sung Eun Bae, Jennifer C. Roberts, Amandine Mullier, Lucilla Poston, Paul D. Taylor,Clive W. Coen

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Establishing an animal model of passive exposure to tobacco smoke during pregnancyDOHaD13-1068 S58

Isabel C. R. Werlang, Mariana D. Schiffner, Carmem Pilla, Patricia P. Silveira, Carla Dalmaz,Marcelo Z. Goldani, Fernanda U. Fontella

Experimental induction of anaemia in preterm lambs: feasibility, survival, growth andhaematological outcomes in adulthood

DOHaD13-1251 S58

Alexandra H. Wallace, Stuart Dalziel, Anita Wylie, Amanda van Zyl, Jane Harding, Anne Jaquiery

Experimental neonatal hyperglycaemia and adult glucose homeostasisDOHaD13-1734 S59

Errol Richardson, Ben Ellis, Emmanuel A. Domfey, Christina Georgallou, Paul D. Taylor, Lucilla Poston

Exposure to a cafeteria diet during the suckling period increases fat mass at weaning independentof prenatal dietary exposure

DOHaD13-1529 S59

Mini A. Vithayathil, Zhi Ong, Robert Gibson, Beverly Muhlhausler

Genetic and experiential influences on the development of stress vulnerability and resilience inrhesus macaques

DOHaD13-1335 S60

Dario Maestripieri, Stephen Lindell, Christina Barr, Karen Parker

Increased hippocampal gene expression is associated with low birth weight in female non-humanprimate neonates

DOHaD13-1300 S60

Jan P. Buschdorf, Shirlene X. Ong, Michael Meaney, Joanna Holbrook, Mei Lyn Ong, Keefe Chng

Inheritance of stress-dependent epigenetic change in drosophila melanogasterDOHaD13-1364 S61

Ki-Hyeon Seong, Dong Li, Shunsuke Ishii

Intrauterine growth restriction induces early onset of age induced alterations in the estrous cycle infemale growth restricted rats

DOHaD13-1610 S61

Suttira Intapad, Barbara T. Alexander

Long term hypoxia during gestation alters perirenal adipose tissue in the lamb: a trigger for adiposity?DOHaD13-1194 S62

Charles Ducsay, Elizabeth Newby, Caleb Cato, Krista Singleton, Dean Myers

Low insulin-like growth factor 1 in breast milk is associated with lower birth weight and a lowergrowth curve in a cynomolgus macaque model

DOHaD13-1116 S62

Yong Chee Tan, Carine Lim, Louiza Chan, Yap Seng Chong, Peter D. Gluckman, Keefe Chng

Maternal administration of glucocorticoid in early pregnancy alters postnatal pituitary-adrenalresponses to challenge in young sheep

DOHaD13-1147 S63

Shaofu Li, John P. Newnham, Ilias Nitsos, Graeme R. Polglase, Timothy J. Moss, Thorsten Braun, John R. G. Challis

Maternal obesity results in lower energy expenditure in adult offspring when challenged with anobesogenic diet

DOHaD13-1621 S64

Xanthi Maragkoudaki, Matthew Naylor, Timothy South, Joaquim M. Pombo, Lucilla Poston, Paul D. Taylor

Maternal pre-implantation or gestational diet alters fetal bone developmentDOHaD13-1185 S64

Stuart Lanham, Stephanie Marfy-Smith, Franky Lock, Judith Eckert, Adam Watkins, Emma Lucas, RichardO. Oreffo, Tom Fleming, Stephanie Meakins

Maternal undernutrition alters DNA methylation profiles in rat embryonic kidneyDOHaD13-1592 S65

Mariko Hida, Midori Awazu

Melatonin prevents prenatal dexamethasone-induced programmed hypertension in a rat modelDOHaD13-1470 S65

You-Lin Tain, Chien-Ning Hsu, Ting-Hsin Wu, Li-Tung Huang

Metabolic imprinting effect during early growth on extra cellular matrix construction in JapaneseBlack steers

DOHaD13-1533 S66

Aoi Nomura, Ryosuke Fujimura, Sithyphone Khounsakunalath, Kunihiko Saito, Kaori Sakuma, TuyoshiAbe, Shuichi Kaneda, Tetsuji Etoh, Yuuji Shiotsuka, Hideyuki Takahashi, Takafumi Gotoh

Metabolic imprinting effect in beef production: influence of nutrition manipulation during anearly growth stage on PPARg2 and PMRT5 a expressions in the longissimus muscle in wagyu(Japanese Black)

DOHaD13-1753 S66

Sithyphone Khounsaknalath, K Saito, Stefan Maak, A Saito and R Fujimura, K Etoh, K Sakuma, K Kaneda,T Abe, T Etoh, Y Shiotsuka, H Hasebe, H Hasebe, A Elke, H Takahashi1, T Gotoh

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Metabolic phenotype of adult offspring rats exposed to intrauterine mild hyperglycemia and highfat diet in early life

DOHaD13-1377 S67

Kai Zhang, Shuang Wang, Jingmei Ma, Huixia Yang, Huixia Yang

Modelling developmental origins of adult based diseases (obesity) using mesenchymal stem – cellular,molecular and functional approaches

DOHaD13-1713 S67

Vijayalakshmi Venkatesan, Soundarya Madhira, Sowmya K, Sireesha Ganneru, Rajanna A, Venkata M,Raghunath M

Mouse models of FGR show an altered metabolic profile which is reversible following treatmentwith sildenafil citrate

DOHaD13-1241 S68

Karolina Sulek, Joanna L. Stanley, David I. Broadhurst, Irene J. Andersson, Wen Hong, Sandra T. Davidge,Louise C. Kenny, Colin P. Sibley, Rupasri Mandal, David Wishart, Philip N. Baker

Offspring of high fat fed rats do not exhibit evidence of augmented sympathetic functionDOHaD13-1678 S69

Sarah Henry, Ryan Wood-Bradley, Roger Evans, Luise Cullen-McEwen, John Bertram, James Armitage

Repeated ischemia reperfusion in a maternal protein restriction model increases the risk of fetalbrain hemorrhage via P53-signal activation

DOHaD13-1105 S69

Takuya Ito, Kenichi Funamoto, Kiyoe Funamoto, Clarissa L. Velayo, Yupeng Dong, Miyuki Endo, RikaSugibayashi, Keita Iida, Toshiyuki Hayase, Nobuo Yaegashi, Yoshitaka Kimura

The long term consequences of prenatal stress on steroid production and functional zonation ofthe adrenal gland in the spiny mouse

DOHaD13-1700 S70

Tracey Quinn, Karen Moritz, Hayley Dickinson, David Walker

The male disadvantage following preterm birth: role of lung maturationDOHaD13-1386 S70

Noreen Ishak, Takushi Hanita, Foula Sozo, Robert De Matteo, Richard Harding

Transgenerational inheritance of a response to nutritional challenge, and the genetic mechanismsunderlying predictive adaptive responses

DOHaD13-1349 S71

Amy J. Osborne, Sarah M. Morgan, Praneeta Ramsey, Peter K. Dearden

Up-Regulation of prolyl-hydroxylase 3 and surfactant proteins in the fetal lung after maternalexposure to chronic hypoxia

DOHaD13-1385 S71

Erin V. McGillick, Sandra Orgeig, Beth J. Allison, Kirsty L. Brain, Youguo Niu, Nozomi Itani, Katie L.Skeffington, Andrew D. Kane, Emilio A. Herrera, Dino A. Giussani, Janna L. Morrison

Uteroplacental insufficiency acutely affects the expression of adrenal genes encoding rate limiting enzymesof the catecholamine- and steroid-biosynthesis in the fetus – impact on kidney function in later life?

DOHaD13-1282 S72

Eva Nusken, Maria Wohlfarth, Gregor Lippach, Jorg Dotsch, Kai D. Nusken

Broader life course perspectives

Functional capacity and physical activity levels in children and adolescents with congenital heart diseaseDOHaD13-1600 S73

Lucia C. Pellanda, Camila Schaan, Beatriz D. Schaan

Intergenerational associations between parental height and cardiovascular disease risk in theoffspring –findings from the Andhra Pradesh Children and Parents Study (APCAPS)

DOHaD13-1440 S73

Poornima Prabhakaran, Dimple Kondal, Radhakrishna KV, Srinath Reddy, Yoav Ben-Shlomo,George Davey Smith

Is socio-economic transition in a rural area of India associated with cardiovascular risk in children?DOHaD13-1535 S74

Kalyanaraman Kumaran, Smita Kulkarni, Anjali Radkar, Sanjeevanee Mulay, Chittaranjan Yajnik

The unborn siblings of preterm infants, role of maternal age – a follow up register-linkage study ofthe 1987–1990 Finnish birth cohort

DOHaD13-1137 S75

Suvi Turkka, Eero Kajantie, Marja Vaarasmaki, Mika Gissler, Anneli Pouta, Petteri Hovi

Cancer

The placental origins of later cancer risk: results from the Dutch famine birth cohort studyDOHaD13-1539 S75

Tessa Rosebom, Rebecca Painter, Susanne De Rooij, Karin Michels, David Barker

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Tobacco use in rural South India: patterns, smoking dependence, quit attempts and response to agroup counseling intervention for smoking cessation

DOHaD13-1258 S76

Jayakrishnan Radhakrishnan, Aleyamma Mathew, Paul Sebastian

Cardiovascular programming

A longitudinal analysis of blood pressure in a sample of term small for gesational age andappropriate for gestational age infants

DOHaD13-1246 S76

John M. D. Thompson, Rinki Murphy, Karen E. Waldie, Clare R. Wall, Edwin A. Mitchell

Accelerated infant weight gain and risk for non-alcoholic fatty liver disease in early adulthoodDOHaD13-1455 S77

Laura Breij, Gerthe Kerkhof, Anita Hokken-Koelega

Adult survivors of severe fetal anaemia have smaller, thicker walled left ventricles, reducedcoronary perfusion and increased cardiovascular risk

DOHaD13-1115 S77

Alexandra Wallace, Stuart Dalziel, Kent Thornburg, Craig Broberg, Alistair Young, Brett Cowan,Jane Harding

An ultrasound assessment of the heart, kidneys and common carotid arteries in three month oldlambs born moderately preterm

DOHaD13-1088 S78

Paul Lombardo, Michal Schneider, Robert DeMatteo, Richard Harding, Vivian Nguyen, Graeme Polglase,M Jane Black

Associations of cardiovascular risk factors among parents and their offspring of the New Delhibirth cohort

DOHaD13-1567 S78

Dorothy Lall, Shika Sinha, Poornima Prabhakaran, Nikhil Tandon, Ramakrishnan Lakshmy, SantoshBhargava, HPS Sachdev, D Prabhakaran

Developmental changes in cardiac expression of micrornas and their targets involved incardiomyocyte proliferation in fetal and newborn sheep

DOHaD13-1464 S79

Janna Morrison, Doug Brooks, Caroline McMillen, Enzo Porrello, Song Zhang, Kimberley Botting

Diet in early life and the development of cardiometabolic disease risk factors in young adulthoodin Cebu, Philippines

DOHaD13-1657 S80

Nanette Lee Mayol, Isabelita Bas, Judith Borja, Paulita Duazo, Linda Adair

Early detection of cardiac dysfunction after preterm birth by speckle-tracking echocardiographyDOHaD13-1055 S80

Ulf Schubert

Early life stress dysregulates growth and angiogenic factors and increases microvascular densityin the kidney

DOHaD13-1631 S81

Analia Loria

Effects of reactive oxygen species on vascular function in the offspring of protein-restrictedstroke-prone spontaneously hypertensive rats

DOHaD13-1422 S81

Kumiko Takemori, Hiroyuki Ito

Epinephrine, norepinephrine and heart rate response after psychosocial stress in young adults bornpreterm at very low birth weight – the Helsinki Study of very low birth weight adults

DOHaD13-1132 S82

Nina Kaseva, Karoliina Wehkalampi, Riikka Pyhala, Kimmo Feldt, Anu-Katriina Pesonen, Kati Heinonen,Petteri Hovi, Anna-Liisa Jarvenpaa, Sture Andersson, Johan G. Eriksson, Katri Raikkonen, Eero Kajantie

Exercise does not confer cardioprotection or improve vascular function in adult male offspringborn growth restricted

DOHaD13-1230 S82

Laura M. Reyes, Jude S. Morton, Raven Kirschenman, Darren DeLorey, Sandra T. Davidge

Exposure to early life vitamin D insufficiency has lifelong implications for vascular andrenal function

DOHaD13-1307 S84

Marianne Tare, Kristen Bubb, Michelle Kett, Harold Coleman, Kate Denton, Helena Parkington

Fetal growth, early postnatal growth and arterial adventitial thickness in later childhoodDOHaD13-1100 S83

Tim Sullivan, Jason Harmer, Brett Toelle, Guy Marks, David Celermajer, Michael Skilton

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Fetal origins of autonomic control in Peruvian childrenDOHaD13-1513 S84

Monica L. Mispireta, Laura E. Caulfield, Nelly Zavaleta, Mario Merialdi, Diane L. Putnick, Marc H.Bornstein, Janet A. DiPietro

Higher maternal vitamin D status in late pregnancy is associated with reduced aortic stiffness in9-year old children assessed using magnetic resonance imaging

DOHaD13-1221 S85

Jennifer Bryant, Charles Peebles, Mark Hanson, Lucy Davies, Hazel Inskip, Nick Harvey, Cyrus Cooper,Keith M. Godfrey

In vitro culture and embryo transfer alters the regulation of blood pressure in early postnatal lifeDOHaD13-1677 S85

Monalisa Padhee, I. Caroline McMillen, Severence M. MacLaughlin, Song Zhang, David O. Kleemann,Simon K. Walker, Jen Kelly, Skye Rudiger, Janna L. Morrison

Leukocyte telomere length is associated with elevated plasma glucose and HBA1c in young healthymen independently of birth weight

DOHaD13-1046 S86

Louise Groth Grunnet, Kasper Pilgaard, Christine B. Jensen, Charlotte Brøns, Amra Alibegovic, SusanOzanne, Martin Bennett, Allan Vaag

Maternal B12 insufficiency independently predicts the metabolic risk factors of the offspringat birth

DOHaD13-1437 S86

Antonysunil Adaikalakoteswari, Alexander Lawson, Craig Webster, Catherine Wood, Neil Anderson, PhilipG. McTernan, Gyanendra Tripathi, Manu Vatish, Ponnusamy Saravanan

Maternal diet-induced obesity programmes cardiovascular dysfunction in the offspringDOHaD13-1279 S87

Heather L. Blackmore, Denise Fernandez-Twinn, Yougou Niu, Dino A. Giussani, Susan E. Ozanne

Maternal parameters influencing the developmental programming of offspring metabolic diseasefollowing maternal diet-induced obesity

DOHaD13-1596 S87

Maria Alfaradhi, Heather Blackmore, Denise Fernandez-Twinn, Susan Ozanne

Maternal smoking behavior in early pregnancy is associated with parasympathetic nervous systemactivation in the offspring at age 5-6 years: the ABCD-study

DOHaD13-1442 S88

Tanja Vrijkotte, Maaike Gademan, Susanne D. Rooij, Tessa Roseboom, Marcel Twickler

Moderate preterm birth in a sheep model: effects on postnatal body growth and arterial pressureDOHaD13-1487 S89

Vivian Nguyen, Robert De Matteo, Richard Harding, Graeme Polglase, Mary Jane Black

Pre-weaning growth hormone treatment reverses maternal undernutrition-induced endothelialdysfunction, hypertension and alters heart development in adult offspring

DOHaD13-1297 S89

Clint Gray, Minglan Li, Clare Reynolds, Mark Vickers

Pregnancy as a critical period for the development of cardiovascular risks for womenDOHaD13-1181 S90

Abdullah Mamun

The effect of early life nutrition on baroreceptor control mechanisms of blood pressure in adult sheepDOHaD13-1565 S90

Kirsten R. Poore, Francesca Paltenghi, Jane K. Cleal, Mark A. Hanson, Lucy R. Green

The role of programming, growth trajectories and infant feeding in explaining childhood bloodpressure: the ABCD study

DOHaD13-1520 S91

Marieke De Beer, Manon van Eijsden, Tanja Vrijkotte, Caroline Fall, Clive Osmond, Reinoud Gemke

Ultrasound evaluation of the structure and blood flow in the heart, kidneys and major arteries ofmoderately preterm lambs at term equivalent age

DOHaD13-1355 S91

Paul Lombardo, Michal Schneider, Robert De Matteo, Richard Harding, Vivian Nguyen, Graeme Polglase,M Jane Black

Vascular-related pregnancy complications are associated with morphological alterations inumbilical cord vasculature

DOHaD13-1372 S92

Emilie Herzog, Anniek Reijnierse, Ronald de Krijger, Irwin Reiss, Eric Steegers, Regine Steegers-Theunissen

Woman in delivered with low birth weight have a risk of pregnancy-induced hypertensionespecially gestational hypertension in pregnancy of herself

DOHaD13-1476 S93

Hiroaki Aoki, Naoko Arata, Naoko Sakamoto, Aikou Okamoto, Haruhiko Sago, Atsuko Murashima

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Clinical

Experiences of pediatric health care professionals while dealing with intersex children and theirparents: a qualitative study in a pediatric setting of Karachi, Pakistan

DOHaD13-1694 S93

Shela A. A. Hirani

Is offspring health influenced by maternal vitamin d status in pregnancy? A systematic review andmeta-analysis

DOHaD13-1071 S94

Nicholas C. Harvey, Chris Holroyd, Georgia Ntani, Kassim Javaid, Philip Cooper, Rebecca Moon, Zoe Cole,Tannaze Tinati, Nicholas Bishop on behalf of UK Vitamin D in Pregnancy Working Group, Keith Godfrey,Elaine Dennison, Janis Baird, Cyrus Cooper and UK Vitamin D in Pregnancy Working Group

Risk factors for retinopathy of prematurity in preterm low birth weight neonates duringperipartum

DOHaD13-1357 S94

Yan Chen, Jun Zhang

Communicating science and DOHaD

Lessons learned on teaching that early life lasts a lifetime since Portland DOHaD 7DOHaD13-1052 S95

Stephen Bezruchka

Delivery, lactation and weaning - role in DOHAD

Association between breast feeding and childhood obesity among Pakistani school-going childrenDOHaD13-1686 S95

Saima A. A. Sachwani, Rozina Karmaliani, Shela Hirani, Asif Raza Khowaja

Changes in levels of milk long chain polyunsaturated fatty acids and neurotrophins across lactationin preeclampsia

DOHaD13-1499 S96

Sadhana Joshi on behalf of Nutritional Medicine, Kamini Dangat, Anitha Kilari, Sanjay Lalwani,Savita Mehendale

Does breast milk adiponectin affect infant adiposity?DOHaD13-1543 S96

Hamid Jan Jan Mohamed, See Ling Loy, Marhazlina Mohamed, Yu Wang

Exclusive breastfeeding reduces adolescent metabolic disease in individuals at high genetic riskDOHaD13-1658 S97

Scott White, Leon Adams, John Olynyk, Koya Ayonrinde, Stephen Lye, John Newnham, Craig Pennell

Impact of cesarean section on autism in offspring: a systematic review and meta-analysisDOHaD13-1177 S98

Hong-Tian Li, Qingjun Huang, Zhi-long Wang, Yu-bo Zhou, Jian-meng Liu

Impact of delivery mode on placental transfusion and iron-related hematological indices in termneonates: a systematic review and meta-analysis

DOHaD13-1133 S98

Yu-Bo Zhou, Hong-tian Li, Li-ping ZHU, Jian-meng Liu

Research on the association between feeding practices and weight status of the infants and youngchildren in Kongjiang Community of Shanghai

DOHaD13-1045 S99

Jing-Qiu Ma, Xiao-yang Sheng

DOHaD and public health

DOHaD theories and ethical issues: a literature searchDOHaD13-1738 S99

Antonio Cunha, Marcelo Land

Effects of maternal gestational diabetes mellitus on offspring overweight and obesity in childhoodin China

DOHaD13-1331 S100

Yaling Zhao, Runmei Ma and Obstetrics and Gynecology, Pediatricsthe First Affiliated Hospital of KunmingMedical University

Growth patterns in appropriate for gestational age infants of gestational diabetic mothers duringthe first year

DOHaD13-1332 S100

Yaling Zhao, Runmei Ma and Obstetrics and Gynecology, Pediatrics, the First Affiliated Hospital of KunmingMedical University

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Higher glucose, insulin and insulin resistance (HOMA-IR) in childhood predict adversecardiovascular risk profile in early adulthood: Pune Children Study

DOHaD13-1564 S101

Chittaranjan Yajnik, Prachi Katre, Suyog Joshi, Kalyanaraman Kumaran, Anand Pandit, Caroline Fall

Identification of biological pathways influenced by multiple maternal factors in 4 different celltypes of newborn twins using genome-wide methylation arrays

DOHaD13-1663 S102

Yuk Jing Loke, Lavinia Gordon, John Galati, Richard Saffery, Jeff Craig

Including DOHaD elements in a model of public policy for achieving adequate early nutrition inthe obstetric control program: controlate y progresa, in Caracas, Venezuela

DOHaD13-1715 S102

Marianella Herrera, Julio Castro, Jorge Dıaz-Polanco, Jorge Hernandez-Rojas, Carlos Walter

Intra uterine or post natal growth matters for the metabolic profile of Sri Lankan childrenDOHaD13-1183 S103

Vithanage P. Wickramasinghe, Carukshi Arambepola, P. Bandar, M. Abeysekera, S. Kuruppu, P. Dilshan,B.S. Dissanayake

Low whole grain intake among pregnant mothers in Singapore as indicated by plasmaalkylresorcinols and estimated intake from dietary records

DOHaD13-1497 S103

Alastair B. Ross, Majorelee Colega, Ai Lin Lim, Irma Silva-Zolezzi, Catherine Mace, Seang Mei Saw,Kenneth Kwek, Peter Gluckman, Keith M. Godfrey, Yap Seng Chong, Mary F.-F. Chong and GUSTO

Nutritional insufficiency among pre-pregnant and pregnant women in Bogor, West Java, IndonesiaDOHaD13-1638 S104

Siti Madanijah, Dodik Briawan, Rimbawan Rimbawan, Zulaikhah Zulaikhah, Nuri Andarwulan,Lilis Nuraida, Tonny Sundjaya, Laksmi Murti, Priyali Shah, Jacques Bindels

People in the United States of America die younger than those in other rich nations partly becauseof neglect of DOHaD concepts

DOHaD13-1295 S104

Stephen Bezruchka

Skinfold thickness and body fat in urban 6–9 year old children: influence of socioeconomic statusDOHaD13-1410 S105

Rita S. Patil, Shobha A. Udipi

Early embryo and IVF

A higher maternal cardiovascular disease risk score reduces embryonic growth in IVF/ICSIpregnancies

DOHaD13-1398 S105

Kim Wijnands, Evelyne van Uitert, Remco Visser, Jeanine Roeters van Lennep, Anton Koning, Niek Exalto,Eric Steegers, Regine Steegers-Theunissen

Cryopreservation of embryos reduces the risk of small for gestational ageDOHaD13-1480 S106

Michael Davies, Alice Rumbold, Jennifer Marino, Kristyn Willson, Lynne Giles, Vivienne Moore

Disruption of methionine metabolism may cause aberrant protein expression of TEAD4 andCDX2 in bovine preimplantation embryos in vitro

DOHaD13-1545 S107

Shuntaro Ikeda

Exogenous hormones for the treatment of infertility induces sex-specific variations in birthweightand length of gestation

DOHaD13-1479 S107

Michael Davies, Alice Rumbold, Jennifer Marino, Kristyn Willson, Lynne Giles, Vivienne Moore

In vitro fertilization and intracytoplasmic sperm injection are associated with increased glucoselevels at the age of five to six years: the Amsterdam born children and their development study

DOHaD13-1438 S108

Martina Pontesilli, Rebecca C. Painter, Iris J. Grooten, Joris A. M. van der Post, Ben Willem Mol,Tanja Vrijkotte, Sjoerd Repping, Tessa J. Roseboom

Epidemiological studies

Association between maternal adherence to Ramadan fasting during pregnancy and birth weightof the newborn

DOHaD13-1503 S108

Ary I. Savitri, Nasim Yadegari, Julia Bakker, Reyn J. van Ewijk, Diederick E. Grobbee, Rebecca C. Painter,Cuno S. Uiterwaal, Tessa J. Roseboom

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Associations of third trimester fetal blood flow distribution and kidney size with childhoodkidney function

DOHaD13-1108 S109

Marjolein Kooijman, Hanneke Bakker, Albert Hofman, Vincent Jaddoe

Diurnal changes in glucose during pregnancy are associated with macrosomia in the newbornDOHaD13-1511 S110

Graham R. Law

Early and late childbearing as risk factors for fetal growth and adverse birth outcomes: evidencefrom Sao Paulo, Brazil

DOHaD13-1229 S110

Alexandra Brentani, Ana Maria de Ulhoa Escobar, Filumena M. D. S. Gomes, Maria H. Valente,Sandra J. Grisi, Gunther Fink

Estimating the adverse effect of low maternal BMI, smoking, on preterm birth and decreased fetalgrowth, in Japanese women

DOHaD13-1721 S110

Naho Morisaki, Kenji Takeda

Experience of major life events during childhood and development of obesity in adulthood:a co-twin control study

DOHaD13-1717 S111

Marianne E. Vamosi, Berit L. Heitmann, Kyle Raymond, Jindong Ding

Gestational diabetes mellitus (GDM) and changes in retinal microvasculature 6 months after deliveryDOHaD13-1050 S111

Lingjun Li, Yap Seng Chong, Kenneth Kwek, Peter Gluckman, Seang Mei Saw, Tien-Yin Wong

Impact of fetal smoke exposure on respiratory outcomes in school- aged children. The GenerationR study

DOHaD13-1669 S112

Martijn Den Dekker, Agnes M. Sonnenschein - van der Voort, Johan C. De Jongste, Albert Hofman,Vincent V. Jaddoe, Liesbeth Duijts

Maternal caffeine intake and risk of low birth weight: a meta-analysisDOHaD13-1182 S112

Ling-Wei Chen, Yi Wu, Nithya Neelakantan, Mary F.-F. Chong, Rob M. van Dam

Maternal obesity and offspring premature mortality: a follow-up of 1,323,275 person-yearsDOHaD13-1066 S113

Rebecca M. Reynolds, Keith M. Allan, Edwin A. Raja, Sohinee Bhattacharya, Geraldine McNeill,Phil Hannaford, Amanda J. Lee, Siladitya Bhattacharya, Jane E. Norman

Maternal prenatal distress predicts adolescent reported internalising behaviour problems in aprospective birth cohort

DOHaD13-1684 S113

Kim S. Betts, Gail M. Williams, Jacob M. Najman, Rosa Alati

Maternal smoking during pregnancy and adiposity among contemporary Portuguese childrenDOHaD13-1339 S114

Leah Li, Helen Peters, Cristina Padez

N-3 long-chain polyunsaturated fatty acids in breast milk and cognitive function in childhoodDOHaD13-1259 S114

Carolien G. Herraets, Lenie Van Rossem, Johan C. de Jongste, Gerard H. Koppelman, Alet H. Wijga,Henriette A. Smit

Prenatal antibiotic and antifungal medication use are associated with atopic dermatitis and allergicsensitization in 2 year-old children

DOHaD13-1112 S115

Ganesa Wegienka, Suzanne Havstad, Edward Zoratti, Dennis Ownby, Christine Johnson

Prenatal exposure to air pollution and newborn blood pressureDOHaD13-1317 S115

Lenie Van Rossem, Sheryl L. Rifas-Shiman, Steven J. Melly, Itai Kloog, Heike Luttmann-Gibson, AntonellaZanobetti, Brent Coull, Joel Schwartz, Murray Mittleman, Emily Oken, Matthew W. Gillman, PetrosKoutrakis, Diane R. Gold

Relationship between maternal clinic/home blood pressure during pregnancy and birth weight ofnewborns in normotensive women: the Boshi Study

DOHaD13-1656 S116

Noriyuki Iwama, Hirohito Metoki, Takayoshi Ohkubo, Mikiko Katagiri, Mami Ishikuro, Taku Obara, KatuyoYagihashi, Ryusuke Inoue, Hidekazu Nishigori, Takashi Sugiyama, Junichi Sugawara, Nobuo Yaegashi,Kazuhiko Hoshi, Masakuni Suzuki, Shinichi Kuriyama, Yutaka Imai

Relevance of precision in newborn weight in neonatal researchDOHaD13-1544 S116

Harshad Sane, Harsha Chopra, Monika Dayama, Patsy Coakley, Vanessa Cox, Meera Gandhi, SirazulSahariah, Caroline Fall, Ramesh Potdar

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Use of a neural model for prediction of preterm birthDOHaD13-1601 S117

Samara P. Costa, Antonio Augusto M. da Silva, Rosangela F. L. Batista, Viviane C. Cardoso, Marco A.Barbieri, Marcelo Z. Goldani, Jose Eduardo R. Rabelo, Heloisa Bettiol, Alcione M. dos Santos

Validity of recalled birthweight versus a gold standard measurement: systematic review and meta-analysisDOHaD13-1439 S118

Mark Zhang, Susan Shenkin, Supriya Mathur, Rebecca M. Reynolds

Epigenetic and genetic epidemiology

A genetic study of steroid resistance nephrotic syndrome: relationship between -173 G to C polymorphismof macrophage inhibitory factor gene and level of serum macrophage inhibitory factor in children

DOHaD13-1417 S118

Oke Rina Ramayani, Partini Pudjiastuti Trihono, Nanan Sekarwana, Ahmad Hamim Sadewa, Aznan Lelo

Association of FTO and MC4R with child adiposity in SGA, and gene environment interactionswith activity and dietary pattern

DOHaD13-1201 S119

John M. D. Thompson, Rinki Murphy, Angharad Morgan, Rod Lea, Clare Wall, Karen Waldie, LynnetteFerguson, Edwin Mitchell

Cellular energy substrate balance in intrauterine life and developmental programming of birthphenotypes: role of mitochondrial DNA variation and haplogroups

DOHaD13-1637 S119

Pathik Wadhwa, Dimitra Chalkia, Olga Derbeneva, Masha Lvova, Lawrence Shimmin, James Hixson,Sonja Entringer, Claudia Buss, Hyagriv Simhan, Douglas Wallace

Epigenetic memory of gestational diabetes in the infantDOHaD13-1306 S120

Hong Pan, Maggie Lim, Mei Lyn Ong, Clara Cheong, Jun Hao Tan, Kok Hian Tan, Yap-Seng Chong,Michael J. Meaney, Peter Gluckman, Walter Stunkel, Joanna Holbrook

Fetal genetic polymorphisms associated with birth weight and body mass index and intrauterinefetal growth restriction

DOHaD13-1450 S120

Fumihiro Sata, Akiko Eto, Yasuhiro Kanatani, Atsuko Araki, Takahiko Mitsui, Reiko Kishi, Katsuya Nonomura

Genome-wide association analysis suggests influence of glycan metabolic pathway on vitamin B12

levels in indian populationDOHaD13-1536 S121

Suraj S. Nongmaithem, Charu V. Joglekar, Smita Kulkarni, Chittaranjan S. Yajnik, Giriraj R. Chandak

Ghrelin and obestatin levels with polymorphisms of the ghrelin/obestatin gene in small forgestational age infants

DOHaD13-1170 S121

Shulian Zhang, Chao Chen

Increased SLC6A4 DNA methylation at birth is associated with an increased fat mass at 6 yearsDOHaD13-1609 S122

Karen Lillycrop, AiLing Teh, Emma Garratt, Rebecca Clarke-Harris, Robert Murray, Paula Costello,Shelia Barton, Graham Burdge, Hazel Inskip, Cyrus Cooper, Joanna Holbrook, Peter Gluckman,Nicholas C. Harvey, Mark Hanson, Keith Godfrey and The Epigen Consortium

Inter-individual differences in the methylome of neonates: what proportion is driven by in uteroenvironment?

DOHaD13-1308 S122

Ai Ling Teh, Hong Pan, Li Chen, Mei Lyn Ong, Johnny Wong, Sarah Mah, Yap-Seng Chong, Kenneth Kwek,Clara Cheong, Walter Stunkel, Michael Kobor, Michael J. Meaney, Peter Gluckman, Joanna Holbrook

Methylation of a CpG in the promoter region of the NOS3 gene is associated with pre-schoolwheeze in SWS children

DOHaD13-1603 S123

Shelia Barton, Allan Shepherd, Sherry Ngo, ChandraKanth Bhoothpur, Hazel Inskip, Katherine Pike, EmmaGarratt, Tejal Bhatt, Mark Hanson, Peter Gluckman, Cyrus Cooper, Karen Lillycrop, Keith Godfreyand The Epigen Consortium

The RS13266634 type 2 diabetes-risk variant in SLC30A8 is associated with increased fetal growth:the fetal glucose hypothesis

DOHaD13-1655 S124

Scott White, Lawrie Beilin, Trevor Mori, Stephen Lye, John Newnham, Craig Pennell

Two thirds of the genetic variants associated with fetal growth trajectories have established andvalidated associations with obesity and the metabolic syndrome

DOHaD13-1253 S124

Craig E. Pennell, Qi W. Ang, Julie A. Marsh, Scott W. White, Laurent Briollais, Melanie K. White,Lawrence Beilin, John P. Newnham, Stephen J. Lye

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Epigenetics

Adherence to the maternal one-carbon-rich dietary pattern is associated with birth weight andDNA methylation of leptin in very young children

DOHaD13-1672 S125

Jennifer J.F.M. Verheijden-Paulissen, Willemijn M. Meijer, Paul H.C. Eilers, Jeanne H.M. de Vries,P. Eline Slagboom, Bastiaan T. Heijmans, Regine P.M. Steegers-Theunissen

Association between hyponatremia in preterm infants during neonatal period and later elevation ofblood pressure in childhood

DOHaD13-1557 S125

Takayuki Kaneko, Masaki Wada, Akihiko Saitoh, Satoshi Kusuda

Association of imprinting status of IGF2 with the pathophysiology of intrauterine growthretardation rats

DOHaD13-1708 S126

Meihui Zhang, Xiuyun Zhou, Lihong Liao, Xiaoping Luo

Association of maternal and nutrient supply line factors with DNA methylation at the imprintedIGF2/H19 locus in multiple tissues of newborn twins

DOHaD13-1269 S127

Jeffrey M. Craig, Yuk Jing Loke, John Galati, Richard Saffery

Characterization of epigenetic changes in muscle precursor cells during the early onset of insulin resistanceDOHaD13-1309 S127

Wenqing Jean Lee, Yonghui Wu, Radiance Lim, Hilary Chua, Shaillay Dogra, Ai Ling Teh, Mei Lyn Ong,Peter Gluckman, E Shyong Tai, Melvin K. Leow, Yung Seng Lee, Craig McFarlane, Joanna Holbrook,Ravi Kambudar

Comparative methylome analysis of B12 intervention shows enrichment of genes and pathwaysinvolved in obesity and type 2 diabetes

DOHaD13-1573 S128

Dilip Kumar Yadav, Charu V. Joglekar, Hong Pan, Caroline H. Fall, Karen A. Lillycrop,Joanna D. Holbrook, Chittaranjan S. Yajnik, Giriraj R. Chandak

Differentially methylated genes associated with immune function in pregnant women colonizedwith group B streptococcus

DOHaD13-1710 S128

Michelle L. Wright, Cindy M. Anderson, Jody L. Ralph, Joyce E. Ohm

DNA methylation, gene expression and plasma levels of leptin in young low birth weight men andcontrols, before and after a 36 hours fasting intervention

DOHaD13-1054 S129

Line Hjort, Sine W. Jørgsensen, Charlotte Brøns, Linn Gillberg, Elin Hall, Charlotte Ling, Allan Vaag

DNA methylation of SIRT1, the longevity gene, in blood from children at 5–7 years exhibitstemporal stability and predicts adiposity in adolescence

DOHaD13-1396 S130

Rebecca Clarke-Harris, Joanne Hosking, Terence J. Wilkin, Jonathan Pinkney, Alison Jeffery, Brad Metcalf,Keith M. Godfrey, Linda D. Voss, Graham C. Burdge, Karen A. Lillycrop

Early environmental toxicant exposure leads to mesenchymal stem cell epigenomic remodelingDOHaD13-1618 S130

Joyce Ohm, Derek Hovick, Anastasia Lindahl, Dedrick Dan

Epigenetic changes of CDKN2A/2B in peripheral blood mononuclear cells for type 2 diabetesDOHaD13-1434 S131

Ju Luan, Ying Wang, Heung Man Lee, Zhibo Gao, Xin Liu, Vincent, K.L Lam, Kevin Yip, Ting Fung Chan,Wing Hung Tam, Wing Yee So, Keith M. Godfrey, Mark A. Hanson, Juliana C.N. Chan, Ronald C.W. Ma

Epigenetic changes in survivors of preterm birth: effect of gestational age and evidence for a longterm legacy

DOHaD13-1693 S131

Mark Cruickshank, Christiane Theda, Alicia Oshlack, David Martino, Penenope Sheehan, Richard Saffery,Peter Davis, Lex Doyle, Jeffrey M. Craig

Epigenetic memory of maternal depression in the infantDOHaD13-1303 S132

Li Chen, Sarah Mah, Yap-Seng Chong, Helen Chen, Jan Paul Buschdorf, Walter Stunkel, Peter Gluckman,Anne Rifkin-Graboi, Michael Kobor, Michael J. Meaney, Joanna Holbrook

Functional relevance of early pregnancy DNA methylation hypomethylation in preeclampsiaDOHaD13-1620 S132

Cindy M. Anderson, Jody L. Ralph, Michelle L. Wright, Joyce E. Ohm

Gene expression and DNA methylation of PGC-1alpha in liver and muscle of IUGR rats withcatch-up growth

DOHaD13-1407 S133

Xuemei Xie, Lihong Liao, Meihui Zhang, Xiaoping Luo

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Genome wide analysis of comparative transcriptional networks in adipocytes differentiated fromumbilical cord derived mesenchymal stem cells, isolated from growth restricted and normal babies

DOHaD13-1195 S133

Roy Joseph, Jeremie Poschmann, Yhee Cheng Chng, Rami Sukarieh, Jun Hao Tan, Ai Ling Teh, Joanna D. Holbrook,Kai Lyn Ng, Yap Seng Chong, Peter D. Gluckman, Shyam Prabhakar, Walter Stunkel

Glucocorticoids alter DNA methylation in the adult male germline resulting in altered steroidreceptor expression and DNA methylation in offspring

DOHaD13-1594 S134

Sophie Petropoulos, Stephen G. Matthews, Moshe Szyf

Glucocorticoid effects on germline epigenetic reprogramming in the rat – a mechanism for thetransmission of programming effects across generations?

DOHaD13-1096 S134

Catherine M. Rose, Sander van den Driesche, Ashley K. Boyle, Richard M. Sharpe, Richard R. Meehan,Amanda J. Drake

Human fetal growth associates with altered DNA hydroxymethylation of H19 and with expressionand DNA methylation of placental IGF2

DOHaD13-1604 S135

Chinthika Piyasena, Khulan Batbayar, Gopi Menon, Jonathan R. Seckl, Rebecca M. Reynolds, Amanda J. Drake

Human placenta drives developmental plasticity through imprinting controlDOHaD13-1623 S136

Benedetta Izzi, Alexandra Binder, Timothy Barrow, Karin Michels

Identification of CDKN2A as a perinatal epigenetic marker of later adiposityDOHaD13-1509 S136

Karen Lillycrop, Robert Murray, Ai Ling Teh, Clara Cheong, Shaillay Dogra, Rebecca Clarke-Harris,Sheila Barton, Paula Costello, Emma Garratt, Graham Burdge, Cyrus Cooper, Hazel Inskip,Fabian Yap, Lee Yung Seng, Chong Yap Seng, Joanna D. Holbrook, Peter Gluckman, Nick Harvey,Mark Hanson, Keith Godfrey and EpiGen Consortium

Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatallyin the mouse hypothalamus

DOHaD13-1416 S137

Ge Li, Wenjuang Zhang, Maria S. Baker, Eleonora Laritsky, Richard B. Simerly, Rui Chen, Lanlan Shen,Robert A. Waterland

Mechanism of programmed obesity in intrauterine growth restricted newborns: epigeneticmediated early induction of adipocyte differentiation contributes to enhanced adipogenesis

DOHaD13-1750 S138

Mina Desai Ph.D, Juanita Jellyman Ph.D, Guang Han M.D., Marie H. Beall M.D.,Michael G. Ross M.D., M.P.H.

Methylation levels of the placental facilitated transporter TAT1 are related to maternal bodycomposition prior to pregnancy

DOHaD13-1706 S138

Claire L. Simner, Rohan M. Lewis, Hazel M. Inskip, Cyrus Cooper, Mark A. Hanson, Keith M. Godfrey,Nicholas C. Harvey, Karen A. Lillycrop, Jane K. Cleal and The Southampton Woman’s Survey Study Group

Micro-RNA let7e in plasma as marker of early metabolic dysfunction in pre-pubertal subjectsDOHaD13-1617 S139

Bernardo J. Krause, Ivo Carrasco-Wong, Angelica Dominguez, Pilar Arnaiz, Marcelo Farias, FranciscoMardones, Paola Casanello

Molecular harbingers of diabetes in the non-human primateDOHaD13-1250 S139

Mei Lyn Ong, Peck Yean Tan, Jan Paul Buschdorf, Walter Stunkel, Paul Robson, Jun-Tao Li, NiranjanNagarajan, Louiza Chan, Peter Gluckman, Keefe Chng, Michael Meaney, Joanna Holbrook

Novel paternal genome effects on placental and fetal phenotype at midgestationDOHaD13-1691 S140

Consuelo Estrella, Ruidong Xiang, Carolyn Fitzsimmons, Zbignew Kruk, Brian Burns, Claire Roberts,Stefan Hiendleder

Peroxisomal proliferator activated receptor-gamma-co-activator-1alpha promoter methylation inblood from children at 5–7 years predicts their adiposity from 9 to 14 years

DOHaD13-1341 S141

Rebecca Clarke-Harris, Joanne Hosking, Terence J. Wilkin, Jonathan Pinkney, Alison Jeffery, Brad S.Metcalf, Keith M. Godfrey, Linda Voss, Karen A. Lillycrop, Graham Burdge

Pregnancy complications and duration of pregnancy affect umbilical cord blood cell populations:implications for future epigenetic studies

DOHaD13-1374 S141

Emilie Herzog, Marten van der Zee, Alex Eggink, Jacqueline Lagendijk, Jingzhen Hou, Robert de Jonge, EricSteegers, Regine Steegers-Theunissen

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Prenatal glucocorticoid overexposure may accelerate maturation of the heme pathway througheffects on transcription and DNA methylation in rat liver

DOHaD13-1090 S142

Khulan Batbayar, Lincoln Liu, Jonathan R. Manning, Ashley K. Boyle, Catherine M. Rose,Donald R. Dunbar, Jonathan R. Seckl, Amanda J. Drake

Presence of NF-Y as an epigenetic element on regulatory regions of ID genes in human embryoniccarcinoma cells

DOHaD13-1074 S142

Farideh Moeinvaziri, Raha Favaedi, Maryam Shahhoseini

The impact of parental environment on embryonic development: methylome and transcriptomeanalysis on the same embryos

DOHaD13-1274 S143

Marc A. Sirard, Claude Robert, Beatrice deMontera, Habib Shojaei Saadi, Dominic Gagne

Ethnic and cultural variation

Customized versus population based birth weight curves: does it make a difference for ethnic groups?DOHaD13-1098 S144

Tanja Vrijkotte, Jason Gardosi, Alike de Roon-Immerzeel, Karien Stronks, Wessel Ganzevoort

Diet patterns among low income women of reproductive age in MumbaiDOHaD13-1683 S144

Sarah Kehoe, Devi Shivshankaran, Harsha Chopra, Sirazul Sahariah, Meera Gandhi, Harshad Sane,Vanessa Cox, Patsy Coakley, Barrie Margetts, Ramesh Potdar, Caroline Fall

Does fructosamine in early pregnancy explain the association between maternal pre-pregnancyBMI and birth weight in a multi-ethnic population?

DOHaD13-1653 S145

Adriette Oostvogels, Nicole Van Melsen, Joke Koelewijn, Manon Van Eijsden, Tanja Vrijkotte

Ethnicity, education and marital status are associated with weight gain in pregnancyDOHaD13-1415 S146

Amal Khanolkar, Gillian E. Hanley, Ilona Koupil, Patricia A. Janssen

Obesity and overweight in children from a region of Italian immigration in Southern BrazilDOHaD13-1591 S146

Lucia C. Pellanda, Renata Geremia, William B. de Souza, Hosana Cimadon

Predictors of birth weight (BW) in a multiethnic british populationDOHaD13-1718 S147

H Venkataraman, N Sukumar, J Wilson, K Khunti, P Saravanan

The association of foetal growth rate with systolic blood pressure in young adulthood is modifiedby ethnicity

DOHaD13-1441 S148

Amal Khanolkar, Sara WEDREN, George Ploubidis, Par Sparen, Ilona Koupil

Fetal physiology

A premature increase in circulating cortisol in the very preterm sheep fetus does not stimulateexpression of genes regulating lung liquid reabsorption

DOHaD13-1325 S148

Erin McGillick, Sandra Orgeig, I. Caroline McMillen, Janna L. Morrison

Developmental expression of leptin and its receptor in fetal ovine heart and lungsDOHaD13-1469 S149

Miles J. De Blasio, Sarah L. Kempster, Gordon C. Smith, Katie L. Davies, Brett S. Bernstein, FB PeterWooding, Dominique Blache, Abigail L. Fowden, Alison J. Forhead

Effect of glucocorticoid exposure on leptin and leptin receptor gene expression in fetal ovine heartand lungs

DOHaD13-1467 S149

Miles J. De Blasio, Sarah L. Kempster, Gordon C. Smith, Brett S. Bernstein, Katie L. Davies, FB PeterWooding, Dominique Blache, Dino A. Giussani, Abigail L. Fowden, Alison J. Forhead

Fetal leptin administration improves aspects of lung function and maturation in fetal sheep duringlate gestation

DOHaD13-1268 S150

Miles De Blasio, Sarah L. Kempster, Gordon C. Smith, FB Peter Wooding, Dominique Blache, Abigail L.Fowden, Alison J. Forhead

Fetal stress physiology across gestation is influenced by maternal exposure to trauma in her ownchildhood

DOHaD13-1733 S151

Nora Moog, Claudia Buss, Sonja Entringer, Babak Shahbaba, Daniel Gillen, Curt Sandman, Calvin Hobel,Pathik Wadhwa

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Local effects of pregnancy on connexin 37 and 43 protein expression in ovine uterine arteryendothelium mediate Ca2+-associated endothelial nitric oxide synthase activation

DOHaD13-1343 S151

Ronald R. Magness, Timothy Morschauser, Jayanth Ramadoss, FuXian Yi, Gladys E. Lopez, Ian M. Bird

Pharmacokinetics of theophylline in the fetal sheepDOHaD13-1231 S152

Barent N. Dubois, Samantha Louey, George Giraud, Sonnet Jonker, Ganesh Cherala

Renal function in preterm infants: a study in indigenous and non-indigenous AustraliansDOHaD13-1488 S152

Mary J. Black, Belinda Davidson, Daryl Hartigan, Sian Graham, Danica Ryan, Shanti Diwakarla,Wendy Hoy, Gurmeet Singh

Gestational diabetes

A pre-conceptional micronutrient-rich food supplement prevents gestational diabetes: MumbaiMaternal Nutrition Project

DOHaD13-1512 S153

Sirazul A. Sahariah, Ella Marley-Zagar, Patsy Coakley, Meera Gandhi, Harshad Sane, Monika Dayama,Harsha Chopra, Sarah Kehoe, Nick Brown, Ramesh Potdar, Barrie Margetts, Caroline H. Fall

Association of intrauterine growth restriction, low Apgar score and high ponderal index withperinatal morbidity – infants born from women with pre-gestational diabetes

DOHaD13-1632 S154

Shireen Begum, Laila A. Banu, S M Keramat Ali

Effects of maternal dietary protein, folate and vitamin B12 status on glucose intolerance duringpregnancy

DOHaD13-1492 S154

Mary F.-F. Chong, Majorelee Colega, Ling Wei Chen, Rob M. van Dam, Chuen Seng Tan, Ai Lin Lim,Wei Wei Pang, Shirong Cai, Yung Seng Lee, Seang Mei Saw, Kenneth Kwek, Keith M. Godfrey, YapSeng Chong, Peter Gluckman and GUSTO

Effects of pre-pregnancy BMI and gestational weight gain on LGA incidence among GDM mothersDOHaD13-1462 S155

Dittakarn Boriboonhirunsarn

Exosomes protect human umbilical arteries endothelial cells against hyperglycemiaDOHaD13-1354 S155

Carlos Salomon, Katherin Scholz, Miharu Kobayashi, Murray Mitchell, Gregory Rice

Fasting plasma glucose at the first prenatal visit is associated with fetal birth weight in gestationaldiabetes mellitus

DOHaD13-1073 S156

Bin Liu, Yun Xu, Chongyou An, Ying Zhang, Zilian Wang

GDM among women who are overweight and obese: the effect of BMI category.DOHaD13-1559 S156

Kate E. Martin, Rosalie Grivell, Jodie Dodd, Lisa Yelland

Impact of leptin and adiponectin and that of maternal obesity on the weights at birth and at oneyear old of infants born to women with gestational diabetes mellitus

DOHaD13-1342 S157

Haitian Chen, Linan Xu, Wenjing Zhu, Yanxin Wu, Man Xu, Zilian Wang

Intra-uterine exposure to maternal diabetes and stress-responses in indian childrenDOHaD13-1211 S157

GV Krishnaveni, SR Veena, MP Malathi, A Jones, CHD Fall

Maternal glucose intolerance alters offspring renal developmentDOHaD13-1461 S158

Stacey Hokke, James Armitage, John F. Bertram, Luise Cullen-McEwen

Metformin therapy reduces maternal weight gain in gestational diabetes: a potential for positiveprogramming? Evidence from a systematic review and meta-analysis

DOHaD13-1546 S159

May Oo Khin, Manu Vatish, Simon Gates, Ponnusamy Saravanan

Postnatal oral glucose tolerance test abnormalities (GTT) abnormalities in gestational diabetes(GDM) – can fasting plasma glucose (FPG) replace GTT?

DOHaD13-1732 S159

H Venkataraman, N Sukumar, Z D’Souza, P Saravanan

Prevelance of high risk pregnancy in tertiary care hospitalDOHaD13-1504 S160

Rozina Khalid

The offspring among pregnant diagnosed gestational diabetes in their first pregnancyDOHaD13-1676 S161

Hanne B. Wielandt, Charlotte H. Blunk, Helena Schønemann-Rigel, Mia K. Hansen, Miriam N. Markman

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Health and nutritional literacy

Impact of mothers’ hygiene practices on nutritional status of young childrenDOHaD13-1561 S161

Sarika Verma, Neha Lohia, Rajlakshmi Nair, Padmini S. Ghugre, Shobha Udipi

On Japanese female university students’ perception of developmental origins of health and disease:a questionnaire survey

DOHaD13-1281 S162

Aya Endo, Masahito Oyamada

Scores on the dietary guideline index for children and adolescents (DGI-CA) are associated withinsulin sensitivity in adolescents

DOHaD13-1622 S162

Wendy Chan She Ping-Delfos, Lawrence Beilin, Wendy Oddy, Sally Burrows, Trevor Mori

‘‘Welcoming the baby’’: the use of a social network as health-enhancing toolDOHaD13-1552 S163

Ana Maria D. U. Escobar, Joana A. Ribeiro, Roberta Rivellino, Alexandra V. M. Brentani,Filumena S. Gomes, Maria Helena Valente, Murilo Wadt, Andre Covic, Sandra Grisi, DaniloAlmeida, Patricia Carvalho

Intergenerational factors and inheritance

Consumption of diets with graded fat and carbohydrate content in mice over three generationsinduces changes in indices of growth and metabolism that vary between generations

DOHaD13-1103 S164

Samuel P. Hoile, Leonie R. Grenfell, Sheila Barton, Mark A. Hanson, Karen A. Lillycrop, Graham Burdge

Elevated S-adenosylhomocysteine perturbs adipocyte function but not differentiation viaepigenetic mechanisms

DOHaD13-1449 S164

Sherry Ngo, Xiaoling Li, Renelle O’Neill, Chandrakanth Bhoothpur, Peter Gluckman, Allan Sheppard andDevelopmental Epigenetics Group

Impact of pre-pregnancy parental overweight and obesity on offspring obesity: systematic analysisand meta analysis

DOHaD13-1174 S165

Nurzalinda Zalbahar, Mamun Abdullah

MAGA’s: possible candidates for environmental factors mediating DOHaD effectsDOHaD13-1237 S166

William Johnson, Steven Buyske, Edward S. Stenroos

Maternal PCOS diagnosis and its implication for congenital birth defects and hospital admissionsin the offspring

DOHaD13-1310 S166

Dorota A. Doherty, John P. Newnham, Carol Bower, Roger Hart

Multigenerational programming of adult HPA function and behavior by single course antenatalglucocorticoid

DOHaD13-1234 S167

Vasilis G. Moisiadis, Paul Blakeley, Alisa Kostaki, Stephen G. Matthews

Transgenerational maternal effects on dairy production in New ZealandDOHaD13-1356 S168

Boyd W Gudex, Dave L Johnson, Kuljeet Singh

Interventional studies – clinical

A community based randomised controlled trial of pre-conceptional micronutrient supplementa-tion to influence programming of diabesity – the Pune Intervention Study

DOHaD13-1537 S168

Kalyanaraman Kumaran, Pallavi Yajnik, Himangi Lubree, Charudatta Joglekar, Dattatray Bhat,Prachi Katre, Urmila Deshmukh, Caroline Fall, Chittaranjan Yajnik

A daily snack containing green leafy vegetables, fruit and milk for 12 weeks increases women’serythrocyte docosahexanoic acid – a randomised controlled trial in slums of Mumbai, India

DOHaD13-1263 S169

Harsha V. Chopra, Sarah Kehoe, Dnyaneshwar Tarwade, Harshad N. Sane, S A. Sahariah, Vanessa Cox,Ramesh Potdar, Caroline Fall, Sadhana Joshi

A novel antibiotic for the treatment of intrauterine ureaplasma and mycoplasma infection:pharmacokinetic studies in the pregnant sheep model

DOHaD13-1392 S169

Jeffrey A. Keelan, Matthew W. Kemp, Matthew Payne, David Johnson, Sarah Stock, Masatoshi Saito,Prabhavathi Fernandes, John P. Newnham

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Chips-child: follow up of a RCT of differential blood pressure control during pregnancy onoffspring health

DOHaD13-1344 S170

Tessa Rosebom and CHIPS CHILD working group

Impact of an unsupervised walking intervention during pregnancy on post-partum weightretention and infant outcomes

DOHaD13-1376 S170

Kai Ling Kong, Christina G. Campbell, Kelly A. Wagner, Anna D. Peterson, Lorraine M. Lanningham-Foster

Increasing women’s intake of green leafy vegetables, fruit and milk pre-conceptionally and throughpregnancy increases birthweight: a randomised controlled trial in mumbai, india (MumbaiMaternal Nutrition Project)

DOHaD13-1688 S171

Ramesh Potdar, Sirazul Sahariah, Meera Gandhi, Monika Dayama, Nick Brown, Harshad Sane,Patsy Coakley, Ella Marley-Zagar, Harsha Chopra, Sarah Kehoe, Devi Sane, Vanessa Cox,Vijaya Taskar, Barrie Margetts, Caroline Fall

Postprandial metabolism and inflammatory markers in overweight adolescentsDOHaD13-1599 S172

Lucia C. Pellanda, Bianca C. Schauren, Vera Lucia Portal

The effect of antenatal lifestyle advice for women who are overweight or obese on newbornanthropometry: the limit randomised trial

DOHaD13-1698 S172

Jodie Dodd, Sheryl Rifas, Lisa Yelland, Andrea Deussen, Matthew Gillman, Rosalie Grivell, DeborahTurnbull, Andrew McPhee, Gary Wittert, Julie Owens, Jeffrey Robinson

Trials and tribulations of a randomised controlled trial – the Mumbai Maternal Nutrition Project,Mumbai, India

DOHaD13-1412 S173

Ramesh Potdar, Sirazul Sahariah, Meera Gandhi, Harsha Chopra, Harshad Sane, Sarah Kehoe, Devi Sane,G Subbulakshmi, Monika Dayama, Nick Brown, Barrie Margetts, Caroline Fall

Life course economics

A health economic model to assess the impact of high birth weight on public healthDOHaD13-1117 S174

Irene Lenoir-Wijnkoop, Mark Nuijten, Eline M. Van Der Beek, Ricardo Uauy

Intergenerational transmission of inequality: maternal endowments, investments, and birth outcomesDOHaD13-1702 S174

Gabriella Conti, James Heckman, Pia Pinger, Arianna Zanolini

Longitudinal determinants of the impact of the economic recession in Republic of Ireland: findingsfrom the Lifeways Cross-Generation Cohort Study

DOHaD13-1152 S175

Cecily C Kelleher, Celine Murrin, Karien Viljoen, John O’Brien, Ricardo Seguardo and LifewaysCross-Generation Cohort Study Steering Group

Longitudinal and cohort studies

A comparison of dual energy X-ray absorptiometry and clinical anthropometry in relation tocardio-metabolic risk factors in the Raine Study

DOHaD13-1528 S175

Denise Demmer, Lawrence J. Beilin, Sally Burrows, Beth Hands, Craig Pennell, Stephen Lye, JennyMountain, Trevor A. Mori

Adverse effect of in-utero alcohol exposure on childhood academic ability: a parental comparisonanalysis supporting a causal influence

DOHaD13-1654 S176

Rosa Alati, George Davey Smith, Sarah lewis, kapil Sayal, E Draper, Jean Golding, Robert Fraser, Ron Gray

Adult height and change in height as predictors of cardiovascular risk factors in young adults froma transitioning population

DOHaD13-1304 S176

Kalyanaraman Kumaran, Suyog Joshi, Himangi Lubree, Clive Osmond, Anand Pandit, ChittaranjanYajnik, Caroline Fall

Antenatal, but not postnatal, factors are associated with an accelerating growth trajectory in earlychildhood

DOHaD13-1523 S177

Lynne Giles, Melissa Whitrow, Alice Rumbold, Chris Davies, Michael Davies, Vivienne Moore

Association of maternal oxidative stress with infant anthropometry in a longitudinal studyDOHaD13-1500 S177

Sadhana Joshi on behalf of Nutritional Medicine, Suchitra Roy, Kamini Dangat, Anitha Kilari, Asmita Joshi,Sanjay Lalwani, Savita Mehendale

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Blood pressure in young adults born at very low birth weight – seven of the cohorts in APIC adultsborn preterm international collaboration

DOHaD13-1311 S178

Petteri Hovi, Sylvia van der Pal, Betty Vohr, Maureen Hack, Lex Doyle, Kari Anne Indredavik Evensen,Ann-Mari Brubakk, Marit Indredavik, Ruth E. Grunau, Sture Andersson, Saroj Saigal, Eero Kajantie

Childhood growth and weight gain and adult waist circumference in five low- and middle-incomecountries

DOHaD13-1158 S178

Rebecca Kanter, Aryeh D. Stein, Manuel Ramirez-Zea on behalf of the COHORTS investigators

Circulating angiogenic factors in women with preeclampsiaDOHaD13-1494 S179

Sadhana Joshi on behalf of Nutritional Medicine, Deepali Sundrani, Akriti Sahay, Vidya Patil, Asmita Joshi,Girija Wagh, Sanjay Gupte

Conditional fetal growth in the last trimester: the effect of BMI, gestational weight gain, fastingglucose and placental weight

DOHaD13-1216 S180

Marie Cecilie P. Roland, Camilla M. Friis, Jens Bollerslev, Guttorm Haugen, Tore Henriksen

Developmental screening tools: evaluation of the agreement between 2 different screening tools(ASQ and PEDS-DM) at 9 months in the GUSTO cohort

DOHaD13-1627 S180

Pratibha K. Agarwal, Kok Hian Tan, Helen Chen, Sok Bee Lim, L.M. Daniel, Anne Rifkin-Graboi,Iliana Magiati, Leher Singh, Fabian K. P. Yap, Kenneth Kwek, Marielle Fortier, Shirong Cai,Shu E Soh, Yin Bun Cheung, Sang Chee Chong, Seang Mei Saw, Yap Seng Chong, Michael J. Meaney,Victor S. Rajadurai

Developmental screening tools: evaluation of agreement between ASQ & PEDS at 18 months inthe GUSTO cohort

DOHaD13-1749 S181

Pratibha Agarwal, Kok Hian Tan, Helen Chen, Sok Bee Lim, L.M. Daniel, Anne Rifkin-Graboi,Iliana Magiati, Leher Singh, Fabian K. P. Yap, Kenneth Kwek, Marielle Fortier, Shirong Cai,Shu E Soh, Yin Bun Cheung, Sang Chee Chong, Seang Mei Saw, Yap Seng Chong, Michael J. Meaney,Victor S. Rajadurai

Developmental screening tools: evaluation of agreement between two developmental screeningtools (ASQ and PEDS) at 9 months in the GUSTO cohort

DOHaD13-1748 S181

Pratibha K. Agarwal, Kok Hian Tan, Helen Chen, Sok Bee Lim, L.M. Daniel, Anne Rifkin-Graboi,Iliana Magiati, Leher Singh, Fabian K. P. Yap, Kenneth Kwek, Marielle Fortier, Shirong Cai,Shu E Soh, Yin Bun Cheung, Sang Chee Chong, Seang Mei Saw, Yap Seng Chong, Michael J. Meaney,Victor S. Rajadurai

Determinants of age at menarche in rural Indian girlsDOHaD13-1146 S182

Charudatta Joglekar, Urmila Deshmukh, Dattatray Bhat, Kalyanraman Kumaran, Caroline Fall,Chittaranjan Yajnik

Does early growth predict blood pressure increase during late adult life? an analysis of longitudinaldata from the Helsinki Birth Cohort Study (HBCS)

DOHaD13-1285 S183

Samuel Sandboge, Clive Osmond, Eero Kajantie, Johan G. Eriksson

Early exposure to violence: trajectories of depression and anxiety symptoms among children andadolescents affected by war

DOHaD13-1475 S183

Elizabeth A. Newnham, Ryan K. McBain, Robert Brennan, Theresa S. Betancourt

Early life body mass trajectories as determinants of mortality: 70-year follow-up in the HelsinkiBirth Cohort Study

DOHaD13-1381 S184

Mikaela von Bonsdorff, Timo Tormakangas, Taina Rantanen, Minna K. Salonen, Clive Osmond, David J.Barker, Eero Kajantie, Johan G. Eriksson

Early life nutritional programming of obesity: optimising mother-child cohort studiesDOHaD13-1728 S184

Eline van der Beek on behalf of ILSI Europe Expert Group on Aligning Cohort Studies and The ILSI EuropeMetabolic Imprinting Task Force, Expert Group on Aligning Cohort Studies

Growth of Chinese children in the first two years of life: a comparison of the GUSTO cohort withthe WHO Child Growth Standards’

DOHaD13-1745 S185

Tuck Seng Cheng, Ngee Lek, Yap Seng Chong, Kenneth Kwek, Seang Mei Saw, Keith M. Godfrey,Peter Gluckman, Yin Bun Cheung, Yung Seng Lee, Fabian Yap

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Late bedtimes are associated with less total sleep in 6-month-old childrenDOHaD13-1448 S186

Sara S. Tan, Diaz A. Utama, Daniel Goh, Oon Hoe Teoh, Michael Meaney, Peter Gluckman, Seang MeiSaw, Keith Godfrey, Yap Seng Chong, Kenneth Kwek, Anne Rifkin-Graboi, Joshua J. Gooley

Life-course obesity trajectories are associated with development of non-alcoholic fatty liver diseaseat age 17 years

DOHaD13-1642 S186

Rae-Chi Huang, Oyekoya T. Ayonrinde, John K. Olynk, Trevor A. Mori, Lawrence J. Beilin, Leon A. Adams

Lifetime socio-economic achievements and intergenerational social-mobility of individuals bornlate-preterm

DOHaD13-1399 S187

Kati Heinonen, Johan G. Eriksson, Eero Kajantie, Anu-Katriina Pesonen, David J. Barker, Clive Osmond,Katri Raikkonen

Longitudinal assessment of maternal plasma fatty acids and their associations with cord andplacental fatty acids in normotensive pregnancy

DOHaD13-1498 S187

Sadhana Joshi on behalf of Nutritional Medicine, Nisha Wadhwani, Vidya Patil, Karuna Randhir, GirijaWagh, Sanjay Gupte

Longitudinal changes in adiponectin multimer levels in preterm infantsDOHaD13-1077 S188

Yuya Nakano, Kazuo Itabashi, Motoichiro Sakurai, Madoka Aizawa, Kazushige Dobashi, Katsumi Mizuno

Longitudinal trends in vitamin B12 concentrations in a rural Indian cohort: the Pune MaternalNutrition Study

DOHaD13-1387 S189

C S. Yajnik, D S. Bhat, C V. Joglekar, H G. Lubree, K Kumaran, S S. Naik, CHD Fall

Maternal diet during pregnancy according variation in perinatal environmental and effects ofinfant’s health – IVAPSA birth cohort

DOHaD13-1689 S189

Juliana R. Bernardi, Marina Nunes, Ednara N. Goncalves, Mariana Brito, Marcio B. Alves, Priscyla Rocha,Rafaela D. S. Correa, Tanara Vogel, Vera L. Bosa, Clecio H. da Silva, Isabel C. Werlang, Marcelo Z.Goldani and IVAPSA Birth Cohort

Maternal nerve growth factor levels in women with preeclampsia from two socioeconomic groups:a longitudinal study

DOHaD13-1501 S190

Vandita D’Souza, Savita Mehendale, Girija Wagh, Sanjay Gupte, Vidya Patil, Hemlata Pisal, MadhaviDhobale, Sadhana Joshi

Mother’s marital status and offspring’s socio-economic position in adulthood. the Helsinki BirthCohort Study 1934–1944

DOHaD13-1353 S190

Maiju Mikkonen, Antti Hakkinen, Minna K. Salonen, Clive Osmond, Maarit Olkkola, Johan G. Eriksson,Eero Kajantie

Parental growth and offspring birth weight: pooled analyses from four birth cohorts in low andmiddle income countries

DOHaD13-1458 S191

Yaw Addo, Reynaldo Martorell and Consortium on Health Orientated Research in Transitional Societies

Parenteral nutrition accelerates growth even in healthy VLBWsDOHaD13-1189 S191

Naho Morisaki, Mandy B. Belfort, Rintaro Mori, Marie C. McCormick, Hisashi Noma, Satoshi Kusuda,Masanori Fujimura and Neonatal Research Network of Japan

Pattern of variation of leptin in a cohort of Brazilian pregnant womenDOHaD13-1113 S192

Ana Beatriz Franco-Sena, Livia C. Oliveira, Thatiana J. P. Pinto, Dayana R. Farias, Juliana S. Vaz, Gilberto Kac

Prenatal growth in a Bi-Ethnic cohort from Bradford, UK: the Born in Bradford birth CohortDOHaD13-1119 S193

Tom Norris, Derek Tuffnell, John Wright, Noel Cameron

Pre-conceptional influences on infant and childhood body composition: findings from theSouthampton Women’s Survey

DOHaD13-1218 S193

Hazel Inskip, Sarah Crozier, Mark Hanson, Nicholas Harvey, Sian Robinson, Cyrus Cooper, Keith Godfreyand Southampton Women’s Survey Study Group

Sensitive developmental periods for atherosclerosis: insight from relationships between BMI and heightacross the growing years with carotid intima-media thickness in adulthood

DOHaD13-1369 S194

William Johnson, Marietta Charakida, Diana Kuh, John E. Deanfield, Rebecca Hardy and on behalf of theNSHD scientific and data collection teams

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Slower postnatal growth is associated with increased sympathetic drive at age 5–6: the ABCD-studyDOHaD13-1611 S195

Maaike G. Gademan, Arend W. van Deutekom, Bert-Jan H. van den Born, Marcel T. Twickler,Tanja G. Vrijkotte

Study of asthma genes and the environment: cohort retention over timeDOHaD13-1641 S195

Rishma Chooniedass, Brenda Gerwing, Saiful Huq, Anita Kozyrskyj, Clare Ramsey, Allan Becker

Tea consumption during early pregnancy does not increase the risk of small for gestational age andpreterm delivery in Southern China: a birth cohort study

DOHaD13-1711 S196

Jianrong He, Songying Shen, Yu Liu, Jinhua Lu, Mingyang Yuan, Jun Chen, Lijuan Xiu, Xiaoyan Xia,Yong Guo, Xiu Qiu

The impact of full breastfeeding, partial breastfeeding and formula feeding on infant growthduring the first year of life

DOHaD13-1525 S196

Izzuddin B. M. Aris, Doris Loh, Wei Wei Pang, Seang Mei Saw, Kenneth Kwek, Peter D. Gluckman,Fabian Yap, Yung Seng Lee, Yap Seng Chong and GUSTO Study Group

The long-term effects on growth and blood pressure of antenatal multiple micronutrientsupplementation in Nepal

DOHaD13-1172 S197

Delan Devakumar, Jonathan Wells, Shiva S. Chaube, Naomi M. Saville, Dharma S. Manandhar,Anthony Costello, Jonathan G. Ayres, David Osrin

The relationship between active smoking and high-sensitive C-reactive protein in late adolescenceDOHaD13-1490 S197

Chi Le-Ha, Lawrence J. Beilin, Sally Burrows, Rae-Chi Huang, Wendy H. Oddy, Beth Hands,Trevor A. Mori

Tracking of cardiovascular risk factors from childhood to young adulthood – the PuneChildren’s Study

DOHaD13-1166 S198

Suyog Joshi, Prachi Katre, Kalyanaraman Kumaran, Charudatta Joglekar, Clive Osmond, Dattatray Bhat,Himangi Lubree, Anand Pandit, Chittaranjan Yajnik, Caroline Fall

What is rotten in the state of Denmark: why is Danish health behind the other Western EuropeanNations?

DOHaD13-1296 S199

Stephen Bezruchka

Maternal mood, stress and behavior

All about ‘U’: associations between intra-uterine exposure to prenatal depression and offspringresponses to stress

DOHaD13-1214 S199

Michelle Fernandes, Alan Stein, Krishnamachari Srinivasan, Gladys Menezes, Paul Ramchandani

Association of maternal dietary carbohydrate intake and plasma folate levels with antenatal lowmood and depression

DOHaD13-1495 S200

Mary F.-F. Chong, Jocelyn X. Wong, Majorelee Colega, Ling Wei Chen, Rob M. van Dam, Chuen Seng Tan,Ai Lin Lim, Wei Wei Pang, Shirong Cai, Birit Broekman, Yung Seng Lee, Seang Mei Saw,Kenneth Kwek, Keith M. Godfrey, Yap Seng Chong, Peter Gluckman, Michael J. Meaney,Helen Chen and GUSTO

Between- and within-individual variability in first morning urinary cortisol in pre-pubertal children:potential explanatory variables

DOHaD13-1111 S200

Cindy K. Barha, Katrina G. Salvante, Jianfeng Zhang, Leilei Zeng, Pablo A. Nepomnaschy

Disaster-related prenatal maternal stress affects cognitive and language abilities in toddlers: theIowa Flood Study

DOHaD13-1729 S201

Suzanne King, Michael W. O’Hara, David P. Laplante

DNA methylation signatures of prenatal maternal exposure to a natural disaster: Project Ice StormDOHaD13-1737 S202

Suzanne King, Lei Cao, Moshe Szyf, David P. Laplante

Maternal prenatal depression at critical windows during pregnancy is associated with increasedplacental serotonin and glucocorticoid sensitivity and transfer

DOHaD13-1370 S202

Rebecca M. Reynolds, Anu-Katriina Pesonen, James R. O’Reiilly, Soile Tuovinen, Marius Lahti,Eero Kajantie, Pia Villa, Hannele Laivuori, Esa Hamalainen, Jonathan R. Seckl, Katri Raikkonen

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Maternal perinatal stress and depression predict parent-reported food allergy in offspring in thefirst three years of life

DOHaD13-1541 S203

Monique Robinson, Renee D. Goodwin, Peter D. Sly, Craig E. Pennell, Peter Jacoby, Stephen R. Zubrick,John P. Newnham, Patrick G. Holt

Maternal stress, anxiety and depression increase the risk of small for gestational ageDOHaD13-1233 S203

Ali S. Khashan, Claire Everard, Lesley M. McCowan, Gustaaf Dekker, Rona Moss-Morris, Philip N. Baker,Lucilla Poston, James J. Walker, Louise C. Kenny and SCOPE Consortium

Maternal stress during pregnancy, in both first generation females born of normal birth weight andthose born small, programs second generation male offspring hypertension

DOHaD13-1616 S204

Mary E. Wlodek, Andrew J. Jefferies, Kristina Avevska, Camille Vickneswaran, Jean N. Cheong, AlannaHanvey, Erica Gerace, Karen M. Moritz

Maternal stress during pregnancy programs glucose intolerance in second generation male offspringand exacerbates pancreatic deficits in offspring of females born small

DOHaD13-1524 S205

Jean N. Cheong, Melanie Tran, Andrew J. Jefferies, Karen M. Moritz, Mary E. Wlodek

Pre- and post-partum depression in women living in slums in Mumbai, IndiaDOHaD13-1483 S205

Meera Gandhi, Sirazul Sahariah, Ella Marley-Zagar, Harshad Sane, Sunita Borhade, Patsy Coakley,Vanessa Cox, Ramesh Potdar, Caroline Fall

Preconception maternal exposure to bereavement stress increases the risk of infant and childhooddeath: a Danish population-based study

DOHaD13-1597 S206

Quetzal Q. Class, Preben B. Mortensen, Marianne G. Pedersen, Tine B. Henriksen, Christina Dalman,Brian M. D’Onofrio, Ali S. Khashan

Prenatal maternal exposure to a natural disaster predicts more masculine 2d:4d finger length ratioin girls: Project Ice Storm

DOHaD13-1614 S207

Suzanne King, Peter L. Hurd, Aihua Liu, David P. Laplante

Prenatal maternal stress due to a natural disaster predicts birth weight and length: the IowaFlood Study

DOHaD13-1731 S207

Suzanne King, David P. Laplante, Kelsey N. Dancause, Kimberly J. Nylen, Michael W. O’Hara

Prenatal and postnatal maternal anxiety impact early and late cognitive processes detected byevent-related potentials

DOHaD13-1555 S208

Suet Chian Sam, Diaz Adi Utama, Hui Jun Chong, Birit Broekman, Helen Chen, Jenny Richmond,Seang Mei Saw, Kenneth Kwek, Peter Gluckman, Yap Seng Chong, Keith Godfrey, Michael J. Meaney,Anqi Qiu, Anne Rifkin-Graboi

The effect of lifestyle counseling as prevention of gestational diabetes mellitus: a cluster-randomized controlled trial

DOHaD13-1365 S209

Shuang Wang, Jingmei Ma, Huixia Yang

The foetal flaw in perinatal care: how best to engage women in intergenerational obesity prevention?DOHaD13-1106 S209

Lydia Hearn and Chilld Health Promotion Research Centre

Water and ice: using natural disasters to study prenatal maternal stressDOHaD13-1727 S210

Suzanne King, David P. Laplante

Maternal nutrition and body composition

Effects of a vegetarian food-based intervention on markers of micronutrient status in low-incomeIndian women of reproductive age. A randomised controlled trial

DOHaD13-1414 S210

Sarah Kehoe, Harsha Chopra, Sirazul Sahariah, Meera Gandhi, Dnyaneshwar Tarwande, Nick Brown,Harshad Sane, Vanessa Cox, Clive Osmond, Barrie Margetts, Ramesh Potdar, Caroline Fall

Fish intake during pregnancy, fetal growth, and gestational length: a meta-analysis of 19 EuropeanBirth Cohort Studies

DOHaD13-1136 S211

Vasiliki Leventakou, Theano Roumeliotaki, David Martinez, Henrique Barros, Anne-Lise Brantsaeter,Maribel Casas, Marie-Aline Charles, Sylvaine Cordier, Merete Eggesbø, Manon van Eijsden, FrancescoForastiere, Ulrike Gehring, Eva Govarts, Thorhallur I. Halldorsson, Wojciech Hanke, Margaretha

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Haugen, Denise H. Heppe, Barbara Heude, Hazel M. Inskip, Vincent W. Jaddoe, Maria Jansen, CecilyKelleher, Helle Margrete Meltzer, Franco Merletti, Carolina Molto-Puigmartı, Monique Mommers,Mario Murcia, Andreia Oliveira, Sjurjur F. Olsen, Fabienne Pele, Kinga Polanska, Daniela Porta,Lorenzo Richiardi, Sian M. Robinson, Hein Stigum, Marin Strøm, Jordi Sunyer, Carel Thijs, KarienViljoen, Tanja G. Vrijkotte, Alet H. Wijga, Manolis Kogevinas, Martine Vrijheid, Leda Chatzi

Flaxseed oil during lactation changes milk composition and programming metabolic parametersin male and female rats

DOHaD13-1091 S212

Mariana S. Figueiredo, Deysla S. Guarda, Ligia D. A. Maia, Elaine de Oliveira, Patricia C. Lisboa,Egberto G. de Moura

Human yolk sac adaptation between mother and fetusDOHaD13-1459 S213

Henriette K. Hellebust, Synnøve L. Johnsen, Svein Rasmussen, Mario Merialdi, Torvid Kiserud

Intrauterine growth, maternal predisposition and family background: evidence from Sao Paulo BrazilDOHaD13-1743 S213

Alexandra Brentani, Helena Brentani, Filumena M. D. S. Gomes, Maria H. Valente, Ana P. Scoleze,Ana Maria D. U. Escobar, Sandra J. Grisi, Gunther Fink

Maternal homocysteine concentrations during pregnancy are associated with higher cortisolresponse to stress in Indian adolescents

DOHaD13-1213 S214

GV Krishnaveni, SR Veena, R Somashekara, A Jones, CS Yajnik, CHD Fall

Maternal iron status related to infant iron status: a prospective study in IndonesiaDOHaD13-1739 S214

Rima Irwinda

Maternal malnutrition impacts structure, function and inflammation of key barriers along thenutritional pipeline

DOHaD13-1286 S215

K L. Connor, E Bloise, S G. Matthews, S J. Lye

Patterns of maternal weight and body composition in pregnancy and post-partum and fetal andinfant growth in women with morbid obesity

DOHaD13-1518 S215

Rebecca M. Reynolds, Fiona C. Denison, Shareen Forbes, Amanda J. Drake, Jane E. Norman

The D-tect study, a societal intervention to examine the influence of exposure to vitamin D in fetallife for development of fractures, obesity, and type 1 diabetes later in life

DOHaD13-1397 S216

Berit L. Heitmann, Ramune Jacobsen, Bo Abrahamsen, Marta Bauerek, Claus Holst, Camilla B. Jensen,Joachim Knop, Kyle Raymond, Lone B. Rasmussen, Thorkild I. Sørensen, Allan Vaag

The effect of folic acid addition to juvenile rat offspring from protein restricted dams on bonestructure and function

DOHaD13-1584 S216

Stephanie Meakins, Cyrus Cooper, Stuart Lanham, Richard Oreffo

The mother study: treatment of hyperemesis gravidarum with early enteral tube feeding.A randomized controlled trial study protocol

DOHaD13-1129 S217

Iris J. Grooten, Tessa J. Roseboom, Joke M. J. Bais, Carrie Ris-Stalpers, Ben Willem J. Mol, Joris A. M. vander Post, Rebecca C. Painter

The relation of maternal plasma ferritin to neonatal abdominal adipose tissue compositionDOHaD13-1730 S218

Wei Wei Pang, Mya Thway Tint, Marjorelee T. Colega, Yiong Huak Chan, Rob M. van Dam, Fabian K.Yap, Marielle V. Fortier, Seang-Mei Saw, Peter Gluckman, Kenneth Kwek, Yap-Seng Chong, Keith M.Godfrey, Yung Seng Lee, Mary F. Chong and GUSTO Study Group

Weight loss and nausea and vomiting in pregnancy: effects on cardiometabolic profile of theoffspring at age 5

DOHaD13-1345 S218

Iris J. Grooten, Rebecca C. Painter, Martina Pontesilli, Joris A. M. van der Post, Ben Willem J. Mol, Manonvan Eijsden, Tanja G. Vrijkotte, Tessa J. Roseboom

Mental health disorders and programming

Anxiety of mothers during pregnancy and birth outcomesDOHaD13-1134 S219

Birit F. Broekman, Yiong Huak Chan, Yap-Seng Chong, Kenneth Kwek, Sharon Sung, Charlotte L. Haley,Helen Chen, Cornelia Chee, Anne Rifkin-Graboi, Peter D. Gluckman, Michael Meaney, Seang MeiSaw and Gusto Singapore

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Does late childbearing impact upon offspring behaviours? a Longitudinal Cohort StudyDOHaD13-1272 S220

Jessica Tearne, Monique Robinson, Jianghong Li, Peter Jacoby, Neil McLean

Food allergy behavioral-cognitive abnormalities and neuroinflammation are prevented by adietary intervention with bifidobacterium breve M-16V in combination with short chaingalacto-oligosaccharides and long-chain fructo-oligosaccharides

DOHaD13-1275 S220

Yuliya E. Borre, Sander De Kivit, Mary E. Morgan, Johan Garssen, Berend Olivier, Aletta D. Kraneveld

Life stress events from pregnancy to adolescence and risk of young adult depression & anxietyDOHaD13-1318 S221

Carly E. Herbison, Karina L. Allen, Monique Robinson, Julie A. Marsh, John P. Newnham, Craig E. Pennell

Maternal emotional reactivity during pregnancy and offspring externalizing symptoms 16 years laterDOHaD13-1699 S221

Michelle Horner, Kevin Kim, Ralph Tarter

Placental weight and sleep onset among infants: Hamamatsu Birth Cohort (HBC) StudyDOHaD13-1245 S222

Kenji J. Tsuchiya, Ryosuke Asano, Taeko Harada, Yumeno Kugizaki, Ryuji Nakahara, Chieko Nakayasu,Akemi Okumura, Yukiko Suzuki, Shu Takagai, Hiroaki Itoh, Nori Takei and HBC Study Team

Pre- and perinatal risk factors for severe mental disorders in adulthoodDOHaD13-1135 S22

Marius Lahti, Johan G. Eriksson, Kati Heinonen, Eero Kajantie, Jari Lahti, Kristian Wahlbeck, SoileTuovinen, Anu-Katriina Pesonen, Tom Forsen, Maiju Mikkonen, David J. P. Barker, Clive Osmond,Katri Raikkonen

The effect of parental prenatal anxiety and depression on the risk of depression in the offspring at18: evidence to support fetal programming?

DOHaD13-1266 S223

Lauren E. Capron, Susannah Murphy, Rebecca Pearson, Glyn Lewis, Alan Stein, Vivette Glover,Paul Ramchandani

Microbiome

Could intestinal microbiota be programmed before weaning?DOHaD13-1549 S223

Fanny Morel, Hugues Piloquet, Raish Oozeer, Anthony Pagniez, Jan Knol, Annemarie Oosting, DominiqueDarmaun, Catherine michel

Elective caesarean delivery increases the risk of type 1 diabetes mellitus: a sibling design studyDOHaD13-1578 S224

Ali S. Khashan, Louise C. Kenny, Cecilia Lundholm, Patricia M. Kearney, Tong Gong, Catarina Almqvist

Maternal and postweaning high fat diet alters caecal microbiota in the adult mouse offspringDOHaD13-1413 S225

Felino R. Cagampang, Yue Liu, Gemma E. Walton, Kimberley D. Bruce, Glenn R. Gibson, Christopher D. Byrne

Maternal gut microbiome is altered by maternal diet: the forgotten barrier in developmental programmingDOHaD13-1401 S225

K L. Connor, C Chehoud, L Chan, S J. Lye

Maternal high fat diet alters the pregnancy microbiome in a mouse modelDOHaD13-1634 S226

Wajiha Gohir, Fiona Whelan, Michael Surette, Caroline Moore, Jonathan Schertzer, Jay Patel, Deborah M. Sloboda

Maternal perinatal microbiota composition and transfer to infantsDOHaD13-1346 S227

Olga Sakwinska, Catherine Ngom-Bru, Shaillay Dogra, Wolfram Brueck, Bernard Berger, Melissa Lepage,Ivan Montoliu Roura, Harald Bruessow, Lee Yung Seng, Kenneth Kwek, Chong Yap-Seng, Peter D.Gluckman, Joanna D. Holbrook

The effect of low birth weight on indoxyl sulfate and OAT1/3 expressionDOHaD13-1643 S227

Jacob Pearson, Barent DuBois, Bonnie Hastings, Alison Edelman, Ganesh Cherala

Paternal factors

Medication influencing the gastro intestinal milieu detrimentally affects sperm motility in menvisiting the preconception outpatient clinic

DOHaD13-1086 S228

Nicole A. Huijgen, Hedwig Goijen, John Twigt, Annemarie Mulders, Jan Lindemans, Gert Dohle, EricSteegers, Joop Laven, Regine Steegers-Theunissen

The contribution of paternal obesity to newborn weight and body compositionDOHaD13-1647 S229

Lodewyk DuPlessis, Andrea Deussen, Rosalie Grivell, Lisa Yelland, Andrew McPhee, Jeffrey Robinson, JulieOwens, Jodie Dodd

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Placental factors and DOHaD

A diet high in sugar and fat alters the lipid metabolic profile of the mouse placentaDOHaD13-1139 S229

Barbara Musial, Owen Vaughan, Abigail Fowden, Amanda Sferruzzi-Perri

A maternal high fat diet results in elevation in amniotic fluid lipid concentrationsDOHaD13-1680 S230

Sarah Henry, Jacqui Weir, Peter Meikle, Ryan Wood-Bradley, Luise Cullen-McEwen, John Bertram,James Armitage

Altered levels and expression of maternal, placental and cord blood antioxidant enzymes inpreterm deliveries

DOHaD13-1496 S230

Sadhana Joshi on behalf of Nutritional Medicine, Madhavi Dhobale, Hemlata Pisal, Savita Mehendale

Cognitive performance in Indian children: relationship to placental morphologyDOHaD13-1150 S231

Sargoor R. Veena, Ghattu Krishnaveni, Krishnamachari Srinivasan, Caroline Fall

Essential fatty acid and prostaglandin pathways are altered in the placentae of fat fed ratsDOHaD13-1273 S231

Marloes Dekker Nitert, Kanchan Vaswani, Melissa Hum, Hsiu-Wen Chan, Sarah L. Henry, Ryan J. Wood-Bradley, Murray D. Mitchell, Gregory E. Rice, James A. Armitage

Identification of candidate genes in human placenta involved in the development ofchildhood allergy

DOHaD13-1244 S232

Astrud Tuck, Annette Osei-Kumah, Zarqa Saif, Vicki Clifton

In vivo studies on fetoplacental glucose consumption in the humanDOHaD13-1085 S232

Ane M. Holme, Marie Cecilie P. Roland, Bjørg Lorentzen, Trond M. Michelsen, Tore Henriksen

Markers of early endothelial dysfunction in IUGR-derived human umbilical vein endothelial cellsrevealed by 2D-Dige and mass spectrometry analyses

DOHaD13-1723 S233

Andres Caniuguir, Bernardo Krause, Paola Casanello

Maternal vitamin D and vitamin D-binding protein: relationship with mRNA expression andepigenetic regulation of placental facilitated amino acid transporters

DOHaD13-1522 S234

Jane K. Cleal, Sheila J. Barton, Claire L. Simner, Karen A. Lillycrop, Hazel M. Inskip, Cyrus Cooper, MarkA. Hanson, Keith M. Godfrey, Nicholas C. Harvey, Rohan M. Lewis and The Southampton Woman’sSurvey Study Group

Omega-3 fatty acid treatment stimulates proliferation of the placental trophoblast cell line HTR8/SVneoDOHaD13-1629 S234

Jing Zhou, Amanda Highet, Tina Bianco-Miotto, Sam Buckberry, Claire T. Roberts, Stefan Hiendleder,Beverly Muhlhausler

Placental myostatin expression is induced by hypoxia and hyperglycemia and represses trophoblastmigration

DOHaD13-1393 S235

Hassendrini Peiris, Carlos Salomon, Katherin Scholz, Maximilian Clissold, Alexander Grainger,Gregory Rice, Murray Mitchell

Placental vitamin D homeostasis and reduced ovine fetal vitamin D status following maternalgestational undernutrition

DOHaD13-1120 S235

Jane K. Cleal, Melissa R. Hargreaves, William D. Fraser, Kirsten R. Poore, Mark A. Hanson, Lucy R. Green

Role of xCT in the delivery of antioxidant precursors in the human placentaDOHaD13-1554 S236

Emma Lofthouse, Jane Cleal, Mark Hanson, Kirsten Poore, Rohan M. Lewis

Sex-specific effects of a single course of antenatal betamethasone treatment on maternal and fetalACTH and cortisol levels in humans

DOHaD13-1373 S237

Franziska Braun, Anne-Katrin Gramzow, Loreen Ehrlich, Annett Husar, Deborah M. Sloboda,John R. G. Challis, Wolfgang Henrich, Andreas Plagemann, Thorsten Braun

The crosstalk between cAMP and MAPK pathways in the regulation of placental 11betahydroxysteroid dehydrogenase 2

DOHaD13-1309 S237

Gang Sun, Jianneng Li

The selection of placental morphological and histopathological variables with the LASSODOHaD13-1337 S238

Yanjun Zhao, Jun Zhang

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Pre and periconceptual period

In vitro culture and embryo transfer alters cardiac metabolism in early postnatal lifeDOHaD13-1673 S238

Monalisa Padhee, I. Caroline McMillen, Song Zhang, Severence M. MacLaughlin, David O. Kleemann,Simon K. Walker, Jen Kelley, Skye Rudiger, Janna L. Morrison

Mothers’ peri-conceptional cortisol levels and their children’s postnatal stress reactivityDOHaD13-1625 S239

Pablo A. Nepomnaschy, Cindy K. Barha, Katrina G. Salvante, Huiting Ma, Leilei Zeng

Preconceptional omega 3 fatty acid supplementation to a micronutrient deficient diet influencesthe expression of hepatic transcription factors in wistar rats

DOHaD13-1491 S239

Akshaya Meher, Asmita Joshi, Sadhana Joshi

Twin conception results in increased fat mass and altered metabolism in adult sheepDOHaD13-1198 S240

Anne L. Jaquiery, Danielle Smeitink, Mark Oliver, Serina Hancock, Clare McLean, Frank Bloomfield

Pre-Clinical

A large scale prospective metabolomic cohort study of first trimester maternal serum revealssystem-wide associations between metabolite concentrations and later pre-eclampsia

DOHaD13-1267 S240

Louise C. Kenny, David I. Broadhurst, Rupasri Mandal, Beamsoo Han, David Wishart, Philip N. Baker

Specific LC-PUFA’s can promote beneficial adiponectin secretion in primary human adipocytesDOHaD13-1315 S241

Marieke Schoemaker, Tania Romacho, Philipp Glosse, Eric A. van Tol, Juergen Eckel

The effect of pubertal exposure to dietary soy on markers of estrogen activity in the breast ofcynomolgus macaques

DOHaD13-1144 S241

Fitriya N. Dewi, Charles E. Wood, Thomas C. Register, Cynthia J. Lees, Timothy D. Howard, ZhiqingHuang, Susan K. Murphy, Janet A. Tooze, J. Mark Cline

Programming of aging

Chronic disease morbidity and treatment behavior of older adults in IndiaDOHaD13-1205 S242

Mini Gomathyamma Krishnakurup

Combination of early life stress and self-reported traumas across the lifespan associates with shorterleukocyte telomere length in later adulthood

DOHaD13-1109 S243

Katri Savolainen, Johan G. Eriksson, Laura Kananen, Eero Kajantie, Anu-Katriina Pesonen, Kati Heinonen,Katri Raikkonen

Maternal folate concentration in early pregnancy predicts newborn telomere lengthDOHaD13-1613 S243

Sonja Entringer, Elissa S. Epel, Jue Lin, Elizabeth Blackburn, Claudia Buss, Babak Shahbaba, Daniel L.Gillen, Raman Venkataramanan, Hyagriv N. Simhan, Pathik D. Wadhwa

Periodization of postnatal ontogeny, according to age-related morbidity and mortality: the impacton programming-of-aging hypothesis in the frame of DOHaD concept

DOHaD13-1298 S244

Viktor I. Goudochnikov

Region-centric analysis on the Infinium 450K array: an aging exampleDOHaD13-1247 S244

Mei-Lyn Ong, Joanna D. Holbrook

The developmental origins of osteoarthritis: findings from the Hertfordshire Cohort StudyDOHaD13-1208 S245

Elaine M. Dennison, Camille Parsons, Mark Edwards, Karen Jameson, Nicholas Harvey, Avan Aihie Sayer,Cyrus Cooper

Programming of appetite and exercise

A maternal ‘junk food’ diet alters the response of the mesolimbic reward system to naloxone inoffspring postweaning

DOHaD13-1236 S246

Jessica Gugusheff, Zhi Yi Ong, Beverly Muhlhausler

Alteration of hypothalamic gene expression by maternal obesity and exerciseDOHaD13-1352 S246

Hasnah Bahari, Mukesh Raipuria, Margaret J. Morris

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Developmental contributions to dietary intake in adult survivors of kwashiorkor and marasmusDOHaD13-1157 S247

Claudia P. Campbell, Asha Badaloo, David Raubenheimer, Peter Gluckman, Mark Hanson, ClaudiaMartinez, Alison Gosby, Stephen Simpson, Clive Osmond, Michael Boyne, Terrence Forrester

Early programming of aerobic and neuromuscular fitness at primary school age. the ABCD-studyDOHaD13-1048 S247

Arend W. Van Deutekom, Mai J. Chinapaw, Manon van Eijsden, Tanja G. Vrijkotte, Reinoud J. Gemke

Early programming of physical activity and sedentary behavior at primary school age. The ABCD-studyDOHaD13-1049 S248

Arend Van Deutekom, Mai J. Chinapaw, Manon van Eijsden, Tanja G. Vrijkotte, Reinoud J. Gemke

Facial responses do basic taste in newborns from mothers with and without gestational diabetes mellitusDOHaD13-1508 S249

Joao G. Alves, Andrea Zacche

Facial responses to basic taste in preterm newbornsDOHaD13-1433 S249

Joao G. Alves, Andrea Z. Sa, Jose Roberto Junior

In-utero and postnatal exposure to high fat diet alters expression of genes that regulate circadianclock function and feeding behaviour in the adult mouse offspring brain

DOHaD13-1400 S250

Felino R. Cagampang, Jasmin L. Shearer, Ravi Mani, Jane K. Cleal, Kerry L. Hyde, Rohan M. Lewis, MarkA. Hanson, Christopher D. Byrne, Kimberley D. Bruce

Maternal sildenafil treatment increases neuropeptide y innervation of the paraventricular nucleusin the brains of offspring

DOHaD13-1249 S250

Joanna L. Stanley, Christine Jasoni, Irene J. Andersson, Sandra T. Davidge, Philip N. Baker

Sensitivity of housekeeping genes in the suprachiasmatic region of the mouse brain to diet and thedaily light-dark cycle

DOHaD13-1575 S251

Jane K. Cleal, James N. Shepherd, Jasmin L. Shearer, Kimberly D. Bruce, Mark A. Hanson, Christopher D.Byrne, Felino R. Cagampang

Programming of behaviour and cognition

Behavioural and neurodevelopmental effects of prenatal stress in neonatal guinea pigsDOHaD13-1404 S252

Greer A. Bennett, Hannah K. Palliser, David W. Walker, Jonathan J. Hirst

Cerebral echo3D and neurodevelopment in newborn. preliminary studyDOHaD13-1540 S252

Benito Cappuccini, Graziano Clerici, Elena Laurenti, Giancarlo Barboni, Gian Carlo Di Renzo

Early life influences on cortical excitability and cognitive outcomes in adolescentsDOHaD13-1391 S253

Luke Schneider, Nicholas R. Burns, Ted Nettelbeck, Michael C. Ridding, Julia B. Pitcher

Effect of gestational diabetes on infants’ brain electrophysiological profileDOHaD13-1502 S254

Shirong Cai, Anqi Qiu, Suet Chian Sam, Michaela Bruntraeger, Hui Jun Chong, Jenny Richmond, Keith Godfrey,Peter Gluckman, Seang Mei Saw, Kenneth Kwek, Yap Seng Chong, Michael Meaney, Anne Rifkin-Graboi

Endocrine disruptor-mediated altered neurogenesis: bisphenol a enhances neural progenitor cellproliferation and differentiation

DOHaD13-1752 S254

Mina Desai Ph.D, Guang Han, M.D, Marie H. Beall, MD, Michael G. Ross

Environmental enrichment reduces anxiety-like behavior in rats programmed by neonatalhyperleptinemia

DOHaD13-1474 S255

Egberto G. Moura, Mabel C. Fraga, Dayse G. Correa-Almeida, Alex C. Manhaes, Elaine Oliveira, Patricia C. Lisboa

Gradual introduction of vegetables in milk and rice at the beginning of weaning: the effects ofearly, varied and repeated exposure on intake of vegetables

DOHaD13-1589 S255

Marion Hetherington, Camille Schwartz, Jerome Madrelle, Fiona Croden, Carel Vereijken, Martine Alles,Hugo Weenen

Identification of perinatal epigenetic marks associated with later neuropsychological functionDOHaD13-1687 S256

Karen Lillycrop, Paula Costello, AiLing Teh, Robert Murray, Rebecca Clarke-Harris, Shelia Barton, EmmaGarratt, Sherry Ngo, Allan Sheppard, Johnny Wong, Shaillay Dogra, Graham Burdge, Cyrus Cooper,Hazel Inskip, Catherine Gale, Peter Gluckman, Nicholas C. Harvey, Mark Hanson, Joanna Holbrook,Keith Godfrey and The Epigen consortium

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Intake of artificially sweetened soft drinks during pregnancy and offspring risk of mood andconduct problems at age 7: A Study from the Danish National Birth Cohort

DOHaD13-1576 S257

Marin Strøm, Ekaterina Maslova, Sjurdur F. Olsen, Thorhallur I. Halldorsson

Maternal consumption of cafeteria diet ameliorates anxiety-like behaviour in male rat offspring ofmothers who exercised before and during pregnancy

DOHaD13-1530 S257

Mukesh Raipuria, Hasnah Bahari, Jayanthi Maniam, Margaret J. Morris

Maternal licorice consumption during pregnancy: offspring’s cognitive, psychiatric, andneuroendocrine outcomes in early adolescence

DOHaD13-1505 S258

Silja Martikainen, Anu-Katriina Pesonen, Kati Heinonen, Riikka Pyhala, Jari Lahti, Kimmo Feldt,Timo Strandberg, Eero Kajantie, Johan Eriksson, Katri Raikkonen

Maternal obesity and offspring’s neurodevelopment: a prospective cohort studyDOHaD13-1131 S259

Lisu Huang, Jun Zhang

Maternal prepregnancy-BMI and infant attention at 9 months of ageDOHaD13-1624 S259

Bea R. Van Den Bergh, Marion Van Den Heuvel, Renee A. Otte, Marijke A. Braeken, Franc C. L. Donkers,Jens Henrichs, Istvan Winkler

Negative maternal perceptions of infant behaviour are associated with increased placentalglucocorticoid and serotonin sensitivity

DOHaD13-1452 S260

Katri Raikkonen, Anu-Katriina Pesonen, James R. O’Reilly, Soile Tuovinen, Marius Lahti, Eero Kajantie,Pia Villa, Hannele Laivuori, Esa Hamalainen, Jonathan R. Seckl, Rebecca M. Reynolds

The opposite effects of prenatal maternal mindfulness and anxiety on auditory event-relatedpotentials of 9-month old infants

DOHaD13-1121 S260

Marion Van Den Heuvel, Renee Otte, Franc Donkers, Istvan Winkler, Bea Van den Bergh

The relationship between nutrition in early childhood and cognitive performance during adolescenceDOHaD13-1484 S261

Anett Nyaradi, Wendy Oddy, Siobhan Hickling, Jianghong Li, Jonathan Foster

Size at birth and physical growth predict neurocognitive function in late adulthood: the HelsinkiBirth Cohort Study

DOHaD13-1265 S262

Jari Lahti, Kati Heinonen, Anu-Katriina Pesonen, Marius Lahti, Soile Tuovinen, Eero Kajantie, CliveOsmond, David J. Barker, Johan G. Eriksson, Katri Raikkonen

Programming of body composition

A maternal low GI diet improves glucose tolerance and reduces visceral fat mass in femaleoffspring

DOHaD13-1312 S262

Mohammed Al-Nussairawi, Amanda Kheng, Jennie Brand-Miller, Sheridan Gentili, Bev Muhlhausler

Abdominal adipose tissue growth during the first year of lifeDOHaD13-1701 S263

Joao G. Alves, vIVIANNE Barros, Adriana Melo, Jousilene Tavares, Melania Amorim

Association between birth weight and body adiposity in childhood: a Brazilian cohort studyDOHaD13-1217 S263

Patricia H. Rondo, Joilane Pereira-Freire, Jesuana Lemos, Artemizia Souza, Camila Menezes

Association between change in maternal adiposity during pregnancy and birth weight andsubcutaneous fat of the newborn

DOHaD13-1087 S264

Christine Sommer, Line Sletner, Anne K. Jenum, Kjersti Mørkrid, Annhild Mosdøl, Kare I. Birkeland

Association between gestational weight gain in overweight/obese women and infant body compositionDOHaD13-1636 S264

Andrea R. Deussen, Roslaie M. Grivell, Lisa N. Yelland, Matthew W. Gillman, Andrew J. McPhee,Jodie M. Dodd

Birthweight, catch-up growth in infancy and markers of overweight and obesity in childhoodDOHaD13-1219 S265

Patricia H. Rondo, Martha R. Sacco, Natalia P. Castro, Veronica L. Euclydes, Jose M. Souza

Bodycomposition in young adults born preterm – the Ester StudyDOHaD13-1064 S266

Marika Sipola-Leppanen, Marjaana Tikanmaki, Hanna-Maria Matinolli, Satu Miettola, Petteri Hovi,Anneli Pouta, Johan G. Eriksson, Marjo-Riitta Jarvelin, Marja Vaarasmaki, Eero Kajantie

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Bodycomposition in young adults born preterm – the Ester StudyDOHaD13-1566 S266

Marika Sipola-Leppanen, Marjaana Tikanmaki, Hanna-Maria Matinolli, Satu Miettola, Petteri Hovi,Anneli Pouta, Johan G. Eriksson, Marjo-Riitta Jarvelin, Marja Vaarasmaki, Eero Kajantie

Can neonatal exendin-4 prevent obesity after IUGR?DOHaD13-1651 S267

Hong Liu, Christopher G. Schultz, Miles De Blasio, Damien Hunter, Rebecca Simmons, Karen L. Kind, JulieA. Owens, Kathryn L. Gatford

Choosing the best anthropometric measures at birth to identify intrauterine growth restrictionDOHaD13-1359 S268

Leixiaoping Lei, Jun Zhang

Consumption of sucrose, not high fructose corn syrup, leads to an increase in visceral andsubcutaneous adiposity in the rat

DOHaD13-1534 S268

Carla R. Toop, Bev Muhlhausler, Kerin O’Dea, Sheridan Gentili

Delivery mode and feeding specifies gut microbiota of infants which influences body compositionDOHaD13-1313 S269

Shaillay Dogra, Olga Sakwinska, Catherine Ngom-Bru, Wolfram Bruek, Bernard Berger, Harald Bruessow,Yung Seng Lee, Fabian Yap, Yap-Seng Chong, Peter Gluckman, Joanna Holbrook

Disproportionate growth of abdominal adipose tissue in first 6 months of life in Asian infantsDOHaD13-1705 S269

Mya-Thway Tint, Marielle V Fortier, Keith M Godfrey, Borys Shuter, Jeevesh Kapur, Victor S Rajadurai,Pratibha Agarwal, Amutha Chinnadurai, Krishnamoorty Niduvaje, Yiong Huak Chan, Izzuddin BinMohd Aris, Shu E Soh, Fabian K.P. Yap, Seang Mei Saw, Yap-Seng Chong, Peter D Gluckman,Yung Seng Lee

Distribution and determinants of abdominal adipose tissue depots in Asian neonates:quantification by MRI

DOHaD13-1609 S270

Mya-Thway Tint, Marielle V Fortier, Keith M Godfrey, Borys Shuter, Jeevesh Kapur, Victor S. Rajadurai,Pratibha Agarwal, Yiong-Huak Chan, Izzuddin Bin Mohd Aris, Shu-E Soh, Kenneth Kwek, Fabian K.P. Yap, Seang Mei Saw, Yap-Seng Chong, Peter D Gluckman, Yung Seng Lee

Effects of age on the developmental timeline for the manifestation of the programmed bone deficitsassociated with fetal growth restriction

DOHaD13-1203 S270

Tania Romano, John D. Wark, Mary E. Wlodek

Effect of maternal glycemia on neonatal adiposity in a multi-ethnic Asian Birth CohortDOHaD13-1724 S271

Izzuddin B. M. Aris, Shu E Soh, Mya Thway Tint, Shen Liang, Seang Mei Saw, Kenneth Kwek,Amutha Chinnadurai, Peter D. Gluckman, Keith Godfrey, Victor S. Rajadurai, Yap Seng Chong,Fabian Yap, Yung Seng Lee

Excessive gestational weight gain is associated with greater perinatal deep and superficialabdominal subcutaneous adipose tissue deposition assessed by neonatal MRI

DOHaD13-1735 S271

Mya-Thway Tint, Shu E Soh, Marielle V Fortier, Borys Shuter, Fabian K.P Yap, Seang Mei Saw,Peter D Gluckman, Yung Seng Lee, Keith M Godfrey, Yap-Seng Chong

H19/IGF2 methylation is associated with body composition changes in young adultsDOHaD13-1646 S272

Rae-Chi Huang, Trevor A. Mori, Lawrence J. Beilin, Craig E. Pennell, Stephen Lye, Jenny Mountain,Jeffrey M. Craig

Longitudinal variance of visceral fat thickness in pregnant adolescentsDOHaD13-1507 S273

Joao G. Alves, Luciana Dutra, Rosangela Cisneiros, Alex Souza, Carolina P. Diniz, Lais Alves, Jose N. Figueiroa

Maternal consumption of high fructose corn syrup, but not sucrose, is associated with increasedfat deposition in the rat offspring post weaning

DOHaD13-1568 S273

Carla R. Toop, Bev Muhlhausler, Kerin O’Dea, Sheridan Gentili

Maternal obesity and excessive weight gain during pregnancy and childhood cardiovascularrisk factors

DOHaD13-1334 S274

Romy Gaillard, Albert Hofman, Eric Steegers, Vincent Jaddoe

Maternal obesity and lipid levels in early pregnancy and the risk of childhood obesity: the motherchild ‘‘RHEA’’ cohort in Crete, Greece

DOHaD13-1169 S274

Vasiliki Daraki, Vaggelis Georgiou, Georgia Chalkiadaki, Stella Koinaki, Marianna Karahaliou, KaterinaSarri, Maria Vassilaki, Stathis Papavasiliou, Manolis Kogevinas, Leda Chatzi

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Metabolic relations of adipose tissue during and after cigarette smoke exposition associated to ahigh-fat diet intake, in young male mice

DOHaD13-1485 S275

Celly Cristina Nascimento-Saba, Rejane P. Gaspar-Reis, Cynthia C. Silva, Aline S. Santos, Yael A. Villaca,Erica Patricia Garcia-Souza

Modifying effect of birth weight on the association between healthy diet score and bodycomposition in adulthood

DOHaD13-1375 S276

Mia-Maria Perala, Satu Mannisto, Eero Kajantie, Johan G. Eriksson

Neonatal body composition by peapod in relation to maternal variablesDOHaD13-1283 S276

Laura Breij, Anita Hokken-Koelega, Marieke Abrahamse, Dennis Acton

Neonatal body composition in a multi-ethnic population; the impact of maternal socioeconomicconditions over the life course

DOHaD13-1409 S277

Line Sletner, Britt Nakstad, Kjersti Mørkrid, Siri Vangen, Kare I. Birkeland, Anne K. Jenum

Postnatal medium chain fatty acids prevent excessive body fat accumulation and improvemetabolic profile in adult mice

DOHaD13-1284 S277

Annemarie Oosting, Diane Kegler, Inga C. Teller, Bert J. van de Heijning, Eline M. van der Beek

Predicitive biomarkers for obesity in a humanized mouse modelDOHaD13-1079 S278

Peter Y. Wielinga, Marieke Schoemaker, Robert Kleemann, Eric A. van Tol, Teake Kooistra

Prenatal DNA damage level is associated with infant adiposity during the first year of lifeDOHaD13-1061 S279

See Ling Loy, Sirajudeen KNS, Hamid Jan B. Jan Mohamed

The influences of and implications of neonatal body fat percentageDOHaD13-1675 S279

Fergus Mccarthy, Ali Khashan, Mairead Kiely, Jonathan Hourihan, Deirdre Murray, Louise Kenny

Transgenerational transmission of bone deficits in growth restricted offspringDOHaD13-1478 S280

Tania Romano, Kristina Anevska, Linda Gallo, Melanie Tran, John D. Wark, Mary E. Wlodek

Validation of anthropometry and bioelectrical impedance against a two-compartment model toassess total body water in Indian rural preschool children

DOHaD13-1593 S280

Urmila Deshmukh, Suyog Joshi, Charudatta Joglekar, Elaine Rush, Anura Kurpad, Chittaranjan Yajnik

Visceral adiposity in the first half of pregnancy: correlation with lipid profile, glucose, insulin andHOMA in the second half of pregnancy

DOHaD13-1423 S281

Joao G. Alves, Andrea Cardoso, Jose N. Figueroa

Programming of immune function, allergy and inflammation

Association between maternal plasma polyunsaturated fatty acid (PUFA) status and childhoodatopy at 18 months of age

DOHaD13-1481 S281

Yamei Yu, Yiong Huak Chan, Shu E Soh, Ai Lin Lim, Oon Hoe Teoh, Anne Goh, Philip C. Calder, SeangMei Saw, Kenneth Kwek, Peter Gluckman, Keith M. Godfrey, Yap Seng Chong, Lynette P.-C. Shek,Mary F.-F. Chong, Hugo P. S. Van Bever and GUSTO

Characterizing the spinal and supraspinal changes associated with exposure to an immunechallenge during the neonatal life

DOHaD13-1580 S282

I. Zouikr, M. A. Tadros, M. James, A. F. Ahmed, K. W. Beagley, V. L. Clifton, R. F. Thorne, C. V. Dayas,R. J. Callister, D. M. Hodgson

Early life overfeeding leads to exacerbated responses to lipopolysaccharide via changes to thehypothalamic-pituitary-adrenal axis

DOHaD13-1360 S283

Sarah Spencer, Guohui Cai, Ilvana Ziko, Rachel Kenny

Formula milk ages enhances kidney programming in IUGR pigletsDOHaD13-1429 S283

Ghada Elmhiri, Thibaut Larcher, Celine Niquet-Leridon, Philippe Jacolot, Narges Bahi-Jaber, SamirBoukthir, Abalo Chango, Frederic J. Tessier, Latifa Abdennebi-Najar

Influence of early life exposures on gut immunity in canadian infants at 4 months – pilot resultsfrom synergy in microbiota research (SYMBIOTA) project

DOHaD13-1519 S284

SL Bridgman, MB Azad, AS Hill, T Konya, H Maughan, D Guttman, MR Sears, AB Becker, S Turvey, JAScott, CJ Field, AL Kozyrskyj and CHILD Research Team

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Lipids and inflammatory markers in newborn umbilical vein blood and associated maternaldiabetes, body mass index and weight gain during pregnancy

DOHaD13-1473 S285

Lucia C. Pellanda, Tatiana Brittos, Fernando Anschau

Maternal dietary supplementation with specific non-digestible oligosaccharides leads to reducedallergic asthma symptoms in their offspring

DOHaD13-1424 S285

Astrid Hogenkamp, Suzan Thijssen, Naomi van Vlies, Leon Knippels, Elena Sandalova, Johan Garssen

Maternal weight, gestational weight gain and offspring health at 2 years of ageDOHaD13-1482 S286

Shu E. Soh, Antony Hardjojo, Keith M. Godfrey, Peter D. Gluckman, Seang Mei Saw, Bee Wah Lee,Oon Hoe Teoh, Anne Goh, Hugo P. S. Van Bever, Lynette Pei-Chi Shek, Yap Seng Chong

mTOR plays an important role in cow’s milk allergy-induced behavioral and immunologicaldeficits

DOHaD13-1388 S286

Jiangbo Wu, Caroline de Theije, Sofia Lopes da Silva, Martien Kas, Kim van Elst, Johan Garssen,Aletta Kraneveld

Neonatal hyperoxia leads to persistent oxidative stress and inflammation in the lungs of miceDOHaD13-1383 S287

Sheena Bouch, Richard Harding, Foula Sozo

Neonatal modulation of serum cytokine profiles by a specific mixture of neutral and acidicoligosaccharides in preterm infants

DOHaD13-1321 S288

Jolice Van Den Berg, Ninke van Zwieteren, Elisabeth Westerbeek, Johan Garsen, Ruurd van Elburg

Offspring of ovalbumin-sensitized mice supplemented with specific non-digestible oligosaccharidesduring pregnancy or lactation display attenuated allergic responses in a model for hen’s eggfood allergy

DOHaD13-1426 S289

Astrid Hogenkamp, Betty van esch, Elena Sandalova, Leon Knippels, Johan Garssen

Role of maternal distress in the perinatal programming of allergic diseaseDOHaD13-1095 S289

Meghan B. Azad, Matthew E. Dahl, Marni Brownell, Mariette J. Chartier, Nicole Letourneau, Anita L. Kozyrskyj

Role of respiratory viruses in early onset childhood rhinitisDOHaD13-1746 S290

Antony Hardjojo, Anne Goh, Oon Hoe Teoh, Lynette P.-C. Shek, Hugo P. S. Van Bever, Jian Yi Soh, ThomasBiju, Boon Huan Tan, Yiong Huak Chan, Mahesh Babu Ramamurthy, Seang Mei Saw, Kenneth Kwek,Yap Seng Chong, Keith M. Godfrey, Peter D. Gluckman, Bee Wah Lee

Stimulated cord blood responses from preterm infants are skewed towards a pro-inflammatoryprofile following pathogen exposure

DOHaD13-1358 S291

Nicolette Hodyl, Natalie Aboustate, Vicki Clifton, Michael Stark

The effect of enteral supplementation of neutral and acidic oligosaccharides on the response topneumococcal, DTaP and Hib vaccinations in preterm infants

DOHaD13-1328 S291

Jolice Van Den Berg, Elisabeth Westerbeek, Guy Berbers, Fiona van der Klis, Ruurd van Elburg

Programming of metabolism

Acute dual effects of methyglyoxal on the secretion of insulin in isolated rat pancreas cells:implication for programming of the metabolism

DOHaD13-1443 S292

Ghada Elmhiri, Luiz F. Barella, Paulo C. D. F. Mathias, Sylvaine Camous, Dler F. D. Mahmood,Latifa Abdennebi-Najar

BAT to WAT – early programming obesity induces brown adipose tissue hypoactivity in ratsDOHaD13-1190 S292

Douglas Lopes Almeida, Kesia P. Rigo, Gabriel S. Fabrıcio, Laize P. Tofolo, Amanda B. Trombini,Audrei Pavanello, Paulo Cezar D. F. Mathias

Birth weight and child growth as risk factors for subclinical atherosclerosis in young adults:evidence from the butanta cohort, Brazil

DOHaD13-1742 S293

Maria H. Valente, Filumena M. D. S. Gomes, Ana Maria de Ulhoa Escobar, Alexandra Brentani,Isabela Bensenor, Sandra J. Grisi

Bone metabolism in obese rats programmed by early weaningDOHaD13-1072 S294

Egberto G. Moura, Ligia D. A. Maia, Carmen C. Pazos-Moura, Elaine Oliveira, Patricia C. Lisboa

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Comparative study of 1-C metabolites during methionine load test in young Indian and US womenDOHaD13-1665 S294

Pallavi Hardikar, Kejal Joshi Reddy, Suyog Joshi, Prachi Katre, Deepa Raut, Himangi Lubree, AnuraKurpad, Satish Kalhan, Chittaranjan Yajnik

Correlational study on expression of IGF-2 and PGC-1A in IUGR ratsDOHaD13-1635 S295

Meihui Zhang, Lihong Liao, Xuemei Xie, Xiaoping Luo

Detailed phenotyping of infant dried blood spot samples by metabolomics and lipidomics revealsextensive differences by age and nutrition

DOHaD13-1685 S295

Philippa Prentice, Albert Koulman, Lee Matthews, Neil Dalton, Charles Turner, Marieke Schoemaker,Eric vanTol, Carlo Acerini, Ken Ong, David Dunger

Dietary supplementation with DHA in preterm neonates alters adipokine levels over the first fourweeks of life

DOHaD13-1465 S296

Michael Stark, Nicolette Hodyl

Early life cardiovascular status, metabolic programming and growth in very young childrenDOHaD13-1107 S297

Kim Wijnands, Sylvia Obermann-Borst, Bas Heijmans, Regine Steegers-Theunissen

Effects of adiponectin on gluconeogenesis via AMPK pathway in adult offspring rats exposed tointrauterine mild hyperglycemia

DOHaD13-1367 S297

Kai Zhang, Jingmei Ma, Huixia Yang

Effects of diet and voluntary maternal exercise during pregnancy on markers of glucose metabolismin skeletal muscles in rat offspring

DOHaD13-1202 S298

Mukesh Raipuria, Hasnah Bahari, Margaret J. Morris

Effects of high-fat feeding during pregnancy and lactation on the behavioral indexes and metabolicchanges, in rat’s offspring

DOHaD13-1280 S298

Celly Saba, Gabrielle L. Gonzalez, Aline S. Santos, Sanderson Alves, Karine Albuquerque, Penha Barradas

Epigenetic influences on long-term phenotype of offspring exposed to intrauterine hyperglycemiaDOHaD13-1366 S299

Jie Yan, Jingmei Ma, Huixia Yang

Excessive arginine intake by lactating rats induces visceral fat accumulation and insulin resistancein later life of offspring

DOHaD13-1720 S299

Lila Otani, Tomomi Mori, Ayaka Koyama, Shin-Ichiro Takahashi, Hisanori Kato

Extensive genome-wide gene expression changes in adipose tissue after 5 days high-fat overfeedingin healthy young men

DOHaD13-1118 S300

Linn Gillberg, Alexander Perfilyev, Charlotte Brøns, Tina Ronn, Allan Vaag, Charlotte Ling

Growing children with bovine metabolism: follow-up results from RussiaDOHaD13-1427 S300

Alevtina Durmashkina, Elena Lukushkina, Olga Netrebenko

Impact of short-term high-fat overfeeding on whole-body energy metabolism in young, healthymen born with a low birth weight

DOHaD13-1047 S301

Charlotte Brøns, Søren K. Lilleøre, Arne Astrup, Allan Vaag

Influence of diet on the methylome of the male germlineDOHaD13-1340 S301

Thomas Chambers, Amanda Drake, Catherine Rose, Sander van den Driesche, Richard Sharpe

Influence of grand-paternal obesity on F2 offspring metabolismDOHaD13-1406 S302

Virginie Lecomte, Christopher A. Maloney, Neil A. Youngson, Margaret J. Morris

Interleukin 18, soluble tumour necrosis factor receptor-1 and adipokines may be more specificprognostic indicators of early life metabolic risk than systemic C-reactive protein

DOHaD13-1648 S303

Rae-Chi Huang, I-Jung Tsai, Lawrence J. Beilin, Patricia Price, Sally Burrows, Trevor A. Mori

Maternal cholestasis during pregnancy programs metabolic disease in offspringDOHaD13-1264 S303

Georgia Papacleovoulou, Oscar Briz, Shadi Abu-Hayyeh, Vanya Nikolova, Xiao Huang, Caroline Ovadia,Maria Vaarasmaki, Marc Baumann, Eugene Jansen, Christiane Albrecht, Marjo-Riita Jarvelin, JoseMarin, AS Knisely, Catherine Williamson

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Maternal high-fat diet alters expression and phosphorylation of key mammalian target ofrapamycin signalling proteins in offspring livers in a mouse model of developmental origins ofnon-alcoholic fatty liver disease

DOHaD13-1666 S304

Hugh Thomas, Dawid Szczepankiewicz, Aditi Jalali, Kimberley D. Bruce, Felino R. Cagampang,Christopher D. Byrne

Maternal omega 3 fatty acid supplementation to vitamin B12 deficient diets improves markers ofmetabolic syndrome in dams

DOHaD13-1493 S305

Sadhana Joshi on behalf of Nutritional Medicine, Amrita Khaire, Richa Rathod, Anvita Kale

Maternal pre-pregnancy BMI, offspring’s postnatal early weight gain and offspring’s metabolicprofile at age 5–6 years: the ABCD-study

DOHaD13-1327 S305

Adriette Oostvogels, Karien Stronks, Manon Van Eijsden, Tanja Vrijkotte

Maternal western diet primes non-alcoholic fatty liver disease in adult offspring in miceDOHaD13-1215 S306

Torsten Plosch, Maurien G.M. Pruis, Agnes Lendvai, Vincent W. Bloks, Mathijs V. Zwier, Albert K. Groen

Mental stress during pregnancy affects to the lipid metabolism mediated by activating the 11b-hydroxysteroid dehydrogenase type1 (11b-HSD1) in the liver of the offspring mouse

DOHaD13-1324 S306

Hiroki Maeyama, Chie Obata, Kazuki Motizuki, Takae Hirasawa, Takeo Kubota

Mesenchymal stem cells derived from small for gestational age newborns exert propertiespromoting rapid catch-up growth and insulin resistance via early response factor-1 and ACOX-2-PGE2 feedback loop

DOHaD13-1242 S307

Rami Sukarieh, Roy Joseph, Shi Chi Leow, Yhee Cheng Chng, Mona Loffler, Jun Hao Tan, Ai Ling Teh,Joanna D. Holbrook, Kai Lyn Ng, Yap Seng Chong, Peter D. Gluckman, Walter Stunkel

Micronutrients in pregnancy as a risk factor for gestational diabetes and effects on mother andbaby: pride study

DOHaD13-1725 S307

N Sukumar, H Venkataraman, A Antonysunil, CS Yajnik, C Fall, P Saravanan and PRiDE study team

Muscarinic receptor subtypes composition in pancreatic islets from obese-programmed ratsDOHaD13-1196 S308

Clarice Gravena, Aryane R. Agostinho, Isis H. Trevenzolli, Julio C. de Oliveira, Luiz F. Barella, Claudineia C. S.Franco, Amanda B. Trombini, Ananda Malta, Rosana Torrezan, Paulo C. F. Mathias, Rosiane A. Miranda

Neonatal insulin resistance and endoplasmic reticulum stress markers in offspring of pregnancieswith maternal obesity, subclinical and cellular perspectives

DOHaD13-1722 S309

Pablo J. Saez, Francisco Westermeier, Roberto Villalobos, Francisco Mardones, Juan P. Kusanovic, Jose A.Poblete, Luis Sobrevia, Paola Casanello, Marcelo Farias

Offspring of non-obese rats fed a high fat diet in pregnancy and suckling develop insulinresistance, cytokine mediated inflammation and mitochondrial dysfunction

DOHaD13-1271 S309

Celine Latouche, Sarah Haywood, Sarah L. Henry, Mark Ziemann, Ross Lazarus, Assam El Osta, BronwynKingwell, James A. Armitage

Outcomes from a dietary 2nd hit: adolescent over nutrition in IUGR baboon offspringDOHaD13-1598 S310

Laura Cox, Robert E. Shade, Kenneth Lange, Shifra Birnbaum, Robert Baker, Peter W. Nathanielsz,Mark J. Nijland

Paternal obesity impacts growth and skeletal muscle metabolism of male offspringDOHaD13-1640 S311

Chris Maloney, Virginie Lecomte, Neil A. Youngson, Margaret J. Morris

Perinatal fructose intake alters maternal, fetal and neonatal hepatic regulation of fatty acid metabolismDOHaD13-1586 S311

Zoe Clayton, Mark H. Vickers, Angelica Bernal, Deborah M. Sloboda

Placental restriction altered insulin actions and increased microrna expression in insulin sensitivetissues of adult offspring in the rat

DOHaD13-1532 S312

Himawan Harryanto, Ezani M. Jamil, Brooke L. Summers-Pearce, Patricia A. Grant, Miles J. De Blasio,Simon Moretta, Wee-Ching Kong, Kathy Gatford, Marie Dziadek, Mary Wlodek, Julie A. Owens

Preterm birth and its complications in sheep alter adult pancreatic beta-cell mass, beta- cellapoptosis and proliferation rates

DOHaD13-1175 S312

Amita Bansal, Jane M. Alsweiler, Kristin L. Connor, Mike Dragunow, Jane E. Harding, Frank H. Bloomfield

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Pre-weaning growth hormone treatment rescues maternal undernutrition-induced meta-inflammationin adult male offspring

DOHaD13-1240 S313

Clare M. Reynolds, Minglan Li, Clint Gray, Mark H. Vickers

Rapid infantile growth as a risk of adult fatty liver – a mouse animal model with intrauterineundernourishment

DOHaD13-1257 S313

Keiko Muramatsu Kato, Hiroaki Itoh, Yukiko K Kohmura, Kaori Yamazaki, Kotomi Nagahashi, ToshiakiShibata, Naomi Furuta, Naoaki Tamura, Chizuko Yaguchi, Toshiyuki Uchida, Kazunao Suzuki,Kazuhiro Sugihara, Naohiro Kanayama

Rapid infantile growth after undernourishment in utero induce transformation from a ‘‘metabolicallyhealthy obese’’ into a ‘‘metabolically morbidly obese’’ by adipose tissue remodeling – a possibleinvolvement of chronic inflammation in adipose tissue-

DOHaD13-1141 S314

Hiroaki Itoh, Yukiko Kohmura-Kobayashi, Keiko Kato-Muramatsu, Kaori Yamazaki, Kotomi Nagahashi,Naoaki Tamura, Toshiyuki Uchida, Kazunao Suzuki, Naohiro Kanayama and Hamamatsu BirthCohort (HBC) Study Team

Sex dependent glucose intolerance in adult offspring from pregnant rats fed low protein dietDOHaD13-1431 S315

Blesson C. Selvanesan, Vijayakumar Chinnathambi, K Sathishkumar, Chandra Yallampalli

Sex-specific plasma glucose intolerance in the prenatal testosterone exposed adult offspringDOHaD13-1432 S315

Blesson C. Selvanesan, Vijayakumar Chinnathambi, Chandra Yallampalli, K Sathishkumar

Short-term treatment with a cholinergic antagonist drug, buscopan, during lactation attenuatesobesity onset in small litter-programed rats

DOHaD13-1192 S316

Kesia Palma Rigo, Ananda Malta, Aline A. de Souza, Julio C. de Oliveira, Luiz F. Barella, Rosiane A.Miranda, Rosana Torrezan, Amanda B. Trombini, Claudineia C. D. S. Franco, Clarice Gravena,Kelly V. Prates, Josiane M. Martin, Paulo C. D. F. Mathias

Single course of antenatal betamethasone administration decreased fetal growth and alteredmaternal-fetal glucose homeostasis

DOHaD13-1305 S316

Anne-Katrin Gramzow, Franziska Braun, Loreen Ehrlich, Annett Husar, Deborah M. Sloboda, John R.G.Challis, Wolfgang Henrich, Andreas Plagemann, Thorsten Braun

The impact of breast milk on obesity: a possible epigenetic mechanism influencing obesityDOHaD13-1378 S317

Heide Temples

Twin conception results in adult adipose tissue with sexually dimorphic changes in glucosetransporter and inflammatory cytokine expression

DOHaD13-1531 S317

Elise Donovan, Anne Jaquiery, Ana-Mishel Spiroski, Mark Oliver, Serina Hancock, Frank Bloomfield

Vitamin B12 deficiency causes adipocyte dysfunction by inducing cholesterol biosynthesis andunfolded protein response

DOHaD13-1558 S318

Antonysunil Adaikalakoteswari, Sarah Finer, Jonathan Moore, Melissa Smart-Halajko, Ciara McCarthy,Philip Voyais, Graham A. Hitman, Philip G. McTernan, Ponnusamy Saravanan, Gyanendra Tripathi

Programming of reproductive function

Altered balance of apoptosis and proliferation in the testes of male offspring born to nutritionallycompromised mothers

DOHaD13-1588 S319

Graciela Pedrana, Mark H. Vickers, Angelica Bernal, M H. Viotti, E Souza, Caroline Moore, Deborah M. Sloboda

Early life inflammatory determinants of reproductive developmentDOHaD13-1550 S319

Luba Sominsky, Erin A. Fuller, Alexander P. Sobinoff, Matthew S. Jobling, Victoria Pye, Eileen A.McLaughlin, Deborah M. Hodgson

Early life influences on testicular function in adulthood using the western Australian pregnancy(Raine Cohort)

DOHaD13-1223 S320

Roger Hart, Dorota A. Doherty, David J. Handelsman, Robert McLachlan, Niels E. Skakkebaek, Jeffrey A.Keelan, John Newnham, Jan E. Dickinson, Robert J. Norman

Higher incidence of preterm births with pregnancy exposure to high temperaturesDOHaD13-1486 S321

Jagjit S. Teji, Rajdeep Singh, Namrata K. Sekhon

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Influence of anthropometry and body composition on attainment of menarche in urban school-going girls in India

DOHaD13-1151 S321

Leena Raje, Amrita Behel, Devaki Gokhale

Maternal caloric restriction during critical developmental windows induces offspring ovarianfollicle loss through ovarian inflammation and ER stress

DOHaD13-1583 S322

Angelica Bernal, Mark H. Vickers, Kaitlyn Chan, Wajiha Gohir, Deborah M. Sloboda

Metabolic programming, lipid and hormonal profile and weight of male reproductive organs ofanimals fed with a diet rich in soybean oil

DOHaD13-1489 S323

Celly Cristina Nascimento-Saba, Cynthia C. Silva, Aline S. Santos, Eliane G. Aguiar, Rejane P. Gaspar-Reis

Sexual orientation in adults born preterm – the Ester StudyDOHaD13-1379 S323

Eero Kajantie, Marika Sipola-Leppanen, Marjaana Tikanmaki, Hanna-Maria Matinolli, Anu-KatriinaPesonen, Satu Miettola, Anneli Pouta, Marjo-Riitta Jarvelin, Katri Raikkonen, Marja Vaarasmaki

Transgenerational effects of maternal high fat diet on offspring reproductive cyclicity andovarian function

DOHaD13-1590 S324

Michael Tsoulis, Mark H. Vickers, Caroline Moore, Kristin L. Connor, Deborah M. Sloboda

Reversibility of programming

Aliskiren in early postnatal life prevents hypertension and reduces asymmetric dimethylarginine inoffspring exposed to maternal caloric restriction

DOHaD13-1471 S324

You-Lin Tain, Chien-Ning Hsu, Chien-Te Lee, Chih-Min Tsai, Li-Tung Huang

Continued protein restriction during lactation protects adult, one year old offspring from thedetrimental metabolic effects of gestational low protein diet exposure

DOHaD13-1517 S325

Anil Dmello, Rani Qasem, Hee Man Tang, Jing Li, Laura Pontiggia

Dietary intake of alpha-linolenic (omega-3) fatty acid in childhood and improved cardiovascularrisk profile in those born small for gestational age: the STRIP study

DOHaD13-1069 S326

Michael Skilton, Katja Pahkala, Jorma Viikari, Tapani Ronnemaa, Olli Simell, Antti Jula, HarriNiinikoski, David Celermajer, Olli Raitakari on behalf of STRIP Study Group

Early life nutrition with a complex lipid matrix diet reverses adverse metabolic programming inIUGR rats

DOHaD13-1261 S326

Heike K. Hoyer-Kuhn, Inga Teller, Hella Bronneke, Pia Nosthoff-Horstmann, Annemarie Oosting,Gregor Lippach, Maria Wohlfarth, Eline M. van der Beek, Jorg Dotsch, Kai D. Nusken

Intra-Amniotic IGF1 treatment of the growth-restricted fetus alters size at birth and perinatal bodycomposition, early postnatal growth velocity and mRNA levels of key somatotrophic genes in liverand muscle

DOHaD13-1204 S327

Ana-Mishel Spiroski, Mark H. Oliver, Travis D. Gunn, Anne L. Jaquiery, Jane E. Harding, Frank H. Bloomfield

Maternal folic acid intake, offspring kidney development and adult blood pressureDOHaD13-1703 S328

Ryan J. Wood-Bradley, Sarah L. Henry, Roger G. Evans, Luise A. Cullen-McEwen, John F. Bertram,James A. Armitage

Maternal melatonin treatment prevents programmed hypertension in offspring exposed to maternalcaloric restriction

DOHaD13-1472 S329

You-Lin Tain, Chien-Ning Hsu, Li-Tung Huang, Chien-Te Lee

Ouabain decreases the risk of hypertension and renal damage by rescueing rat nephrogenesisduring IUGR

DOHaD13-1380 S329

Juan Li, Liang Chen, Jing Yue, Yali Hu

Paternal lifestyle interventions in obese males restores early embryo development and fetal weights,improving the metabolic health and adiposity status in subsequent female offspring

DOHaD13-1633 S330

Nicole McPherson, Hassan Bakos, Brian Setchell, Julie A. Owens, Michelle Lane

Resveratrol prevents hyperleptinemia and central leptin resistance in adult male rats programmedby early weaning

DOHaD13-1083 S331

Patricia C. Lisboa, Elaine Oliveira, Juliana G. Franco, Natalia S. Lima, Nayara Peixoto-Silva,Magna C. Passos, Egberto G. Moura

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Resveratrol treatment rescues hiperleptinemia and improves central leptin signaling in adult ratsprogrammed by maternal high-fat diet consumption in gestation and lactation

DOHaD13-1556 S331

Isis H. Trevenzoli, Juliana G. Franco, Camilla P. Dias-Rocha, Tatiana P. Fernandes, Patricia C. Lisboa,Egberto G. Moura, Carmen C. Pazos- Moura

Running wheel training reverse programming effects in adult obese rats programmed by maternalprolactin inhibition

DOHaD13-1078 S332

Carmen C. Pazos- Moura, Gabriel Boaventura, Gustavo Casimiro-Lopez, Elaine Oliveira, Patricia C.Lisboa, Egberto G. Moura

Taurine supplementation in the setting of maternal obesity partially reverses hepaticpro-inflammatory profiles in neonatal offspring in a sex-specific manner

DOHaD13-1301 S332

Minglan Li, Clare M. Reynolds, Clint Gray, Mark H. Vickers

Toxicology and environmental pollutants

Association between prenatal PCB exposure and obesity development at age 5 and 7: a prospectivecohort study of 656 children from the Faroe Islands

DOHaD13-1371 S333

Jeanett L. Tang-Peronard, Berit L. Heitmann, Helle R. Andersen, Ulrike Steuerwald, Philippe Grandjean,Pal Weihe, Tina K. Jensen

Effect of fetal exposure to bisphenol a on brain mediated by X-chromosome inactivationDOHaD13-1255 S333

Takayuki Kumamoto, Shigeru Oshio

Effects of perfluoroalkylcarboxylic acids and phthalate metabolite on transcriptional activityVia PPARA and PPARA-V227A variant

DOHaD13-1477 S334

Hiroyuki Kojima, Shinji Takeuchi, Kenichi Takahashi, Fumihiro Sata

Endocrine disruptor (bisphenol A) increases proliferation and lipid storage of adipocyte progenitor cellsDOHaD13-1751 S335

Mina Desai Ph.D, Juanita Jellyman, Ph.D, Guang Han, M.D, Marie H. Beall, M.D, Michael G. Ross,M.D., M.P.H.

Intrauterine growth restriction decreases diuretic response of furosemide in rats during adulthoodDOHaD13-1228 S335

Barent N. DuBois, Jacob Pearson, Tahir Mahmood, Duc Nguyen, Kent Thornburg, Ganesh Cherala

Long-term environmental exposure and fetal growth restrictionDOHaD13-1197 S336

Karolina Sulek, Ting-Li Han, Silas G. Villas-Boas, Lesley McCowan, David Wishart, Louise Kenny,Philip N. Baker

Maternal exposure to DEHP and sex hormone levels in cord bloodDOHaD13-1276 S336

Atsuko Araki, Takahiko Mitsui, Chihiro Miyashita, Masahiro Tagawa, Tamie Nakajima, Seiko Sasaki,Tamiko Ikeno, Sachiko Itoh, Emiko Okada, Kazutoshi Cho, Katsuya Nonomura, Reiko Kishi

Multigenerational effects of air pollution on reproductive capacity and fetal development: aexperimental study

DOHaD13-1626 S337

Natalia S. X. Costa, Sabrina A. Santos, Karina V. Marques, Luiz Fernando F. da Silva, Paulo H. N.Saldiva, Mariana M. Veras

Multigenerational effects of BPA alone or in combination with genistein and/or vinclozolin onmaternal behavior in Wistar rats

DOHaD13-1521 S338

Latifa Abdennebi-Najar, Sofiane Boudalia, Folia Mireille, Claire Chabannet, Bruno Pasquis,Laurence Decocq Laurence, Raymond Berges, Marie-Chantal Canivenc-Lavier

Prenatal exposure to persistent organic pollutants (POPs) and child neuropsychologicaldevelopment at 4 years of age

DOHaD13-1149 S337

Marina Vafeiadi, Katerina Koutra, Theano Roumeliotaki, Eleni Fthenou, Georgia Chalkiadaki,Maria Kabouri, Andriani Kyriklaki, Panu Rantakokko, Hannu Kiviranta, Soterios A. Kyrtopoulos,Manolis Kogevinas, Leda Chatzi

Relationship between blood polychlorinated biphenyl level and distance towards the nearestfishing port: a birth cohort study

DOHaD13-1262 S339

Masamichi Hanazato, Masahiro Watanabe, Emiko Todaka, Yoshiharu Matsuno, Hiroko Nakaoka, Chisato Mori

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