Tugas Biofarm Nurdiani Syara Asli
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8/18/2019 Tugas Biofarm Nurdiani Syara Asli
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Data Tablet Ramimprilat (Reference)
Time (hr) Con (mg/l) time inte Averengen Conc (mg/l
0 0 0 0
0.01 1.13 0.01 0.00565
0.02 3.51 0.01 0.0232
0.04 7.23 0.02 0.1074
0.06 11.21 0.02 0.1844
0.08 13.11 0.02 0.2432
0.1 13.15 0.02 0.2626
0.12 14.03 0.02 0.2718
2.5 11.13 2.38 29.9404
3 11 0.5 5.5325
3.5 10.16 0.5 5.294 8.02 0.5 4.545
5 7.15 1 7.585
6 4.89 1 6.02
8 3.16 2 8.05
12 1.28 4 8.88
24 1.03 12 13.86
36 0.55 12 9.48
48 0.23 12 4.6872 0.15 24 4.56
109.52115
0.216
AUC 70! " 109.737
0#693
AUC072
AUC 0-∞ AUC 0-72 ! AUC 72-∞
AUC 72! " C72 " 0.15 "
" 0.693
AUC 072 $ C %&hir "
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Data Tablet Ramimprilat (te#t)
Are% (mg'r/l) Time (hr) Con (mg/l) time int
0 0 0 0
0.00565 0.01 1.02 0.01
0.0232 0.02 2.11 0.01
0.1074 0.04 6.22 0.02
0.1844 0.06 9.01 0.02
0.2432 0.08 10.91 0.02
0.2626 0.1 12.35 0.02
0.2718 0.12 12.29 0.02
29.9404 2.5 11.51 2.38
5.5325 3 10.24 0.5
5.29 3.5 9.03 0.54.545 4 7.31 0.5
7.585 5 5.67 1
6.02 6 3.98 1
8.05 8 2 2
8.88 12 1.15 4
13.86 24 1 12
9.48 36 0.98 12
4.68 48 0.5 124.56 72 0.29 24
0.$2
AUC 70! " 110.7%
0#693
AUC 072
AUC 0-∞ AUC 0-72 ! AUC 72-∞
AUC 72! " C72 " 0.29 "
" 0.693
AUC 072 $ C %&hir "
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Averengen Conc (mg/l) Are% (mg'r/l)
0
0.0051 0.0051
0.01565 0.01565
0.0833 0.0833
0.1523 0.1523
0.1992 0.1992
0.2326 0.2326
0.2464 0.2464
28.322 28.322
5.4375 5.4375
4.8175 4.81754.085 4.085
6.49 6.49
4.825 4.825
5.98 5.98
6.3 6.3
12.9 12.9
11.88 11.88
8.88 8.889.48 9.48
110.33155
&ra'
c+n#entrati+n pla#ma
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0 10 20 30 40 50 60 70 800
5
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ata tablet Ramiprilat (Te#t *# Reference)
Averengen Conc (mg/l)
Averengen Conc (mg/l)
time
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