TEXT BOOK REVIEW

“PATOFISIOLOGI STROKE”

Disusun Oleh:

Dessriya Ambar Rohfiin

G1A014056

Pembimbing :

dr. Muttaqien Pramudigdo, Sp. S

SMF ILMU PENYAKIT SARAF

RSUD PROF. DR. MARGONO SOEKARDJO

FAKULTAS KEDOKTERAN DAN ILMU-ILMU KESEHATAN

UNIVERISTAS JENDERAL SOEDIRMAN

PURWOKERTO

2015

LEMBAR PENGESAHAN

“PATOFISIOLOGI STROKE”

Disusun Oleh :

Dessriya Ambar Rohfiin

G1A014056

TEXT BOOK REVIEW

Disusun untuk memenuhi syarat mengikuti Kepaniteraan Klinik

di bagian Ilmu Penyakit Saraf

RSUD. Prof. Dr. Margono Soekardjo

Disetujui dan disahkan,

pada tanggal November 2015

Pembimbing

dr. Muttaqien Pramudigdo , Sp. S

DAFTAR ISI

COVER..........................................................................................................................i

LEMBAR PENGESAHAN..........................................................................................ii

DAFTAR ISI...............................................................................................................iii

I. PENDAHULUAN.................................................................................................... 1

II. TINJAUAN PUSTAKA..........................................................................................2

A. Definisi................................................................................................................2

B. Klasifikasi...........................................................................................................2

C. Patofisiologi........................................................................................................2

1. Trombus..........................................................................................................2

2. Tromboemboli................................................................................................5

3. Stroke Non-Hemoragik..................................................................................5

4. Perubahan Fisiologi pada Aliran Darah Otak.................................................6

5. Perubahan pada Tingkat Seluler dan Mikrosirkulasi.....................................9

6. Biomolekuler Stroke.......................................................................................10

7. Stroke di Sirkulasi Anterior............................................................................14

8. Stroke di Sirkulasi Posterior...........................................................................20

9. Stroke Hemoragik...........................................................................................26

III. KESIMPULAN.....................................................................................................32

DAFTAR PUSTAKA...................................................................................................33