Prevalensi Kanker Kolorektal pada Usia 20-79 Tahun Berdasarkan Klasifikasi Histopatologi WHO di RSUP H.Adam Malik Medan Periode Januari 2011-Desember 2013

Prevalensi Kanker Kolorektal Berdasarkan Kelompok Usia dan Klasifikasi Histopatologi WHO di RSUP H.Adam Malik Medan Periode Januari 2011-Desember 2013

Dosen Pembimbing :dr. Jamaluddin, Sp. PAIbrena Thaminta Ginting110100014PENDAHULUAN

LATAR BELAKANGDi Dunia : Kanker ke- 3 paling umum Penyebab kematian nomor empat Insidensi : 19,1/100.000 , : 14,4/100.000

Meningkat di Asia (IDI,2009) dan Negara Berkembang Menjadi permasalahan di Indonesia : Urutan ke- 3 ( 1,8/100.000) (Depkes,2006)

(SEER 2013) Dalam rentang usia 20-84 tahun, terbanyak adalah usia 75 84 tahun = 24,1% Gambaran Histopatologi : 70% Moderately-differentiated adenocarsinoma ( Fleming, M., et.al, 2012) Meningkat pada usia muda ( 79Histopatologi adalah Gambaran hasil biopsi Cara Ukur : Data rekam medikAlat Ukur : Rekam medikSkala : OrdinalKategori : Well-differentiated , Moderately differentiated, Poorly differentiatedMetode PenelitianDAFTAR PUSTAKA Abdullah, M., et.al, 2012. Molecular profile of colorectal cancer in Indonesia: is there another pathway? Jakarta: Gastroenterol Hepatol BedBench 2012;5(2):71-78.Alexander, D.D., et.al, 2011. Meta-analysis of prospective studies of red meat consumption and colorectal cancer. USA: Williams & Wilkins. doi:10.1097American Cancer Society, 2011. Colorectal Cancer Facts & Figures 2011-2013. Atlanta, Georgia: American Cancer Society.American Cancer Society, 2014. Colorectal Cancer. Atlanta, Ga: American Cancer Society.Boardman, R. E, 2007. Colorectal Cancer Risks in Relatives of Young-Onset Cases: Is Risk the Same Across All First Degree Relatives? Rochester, Minnesota, USA: Clin Gastroenterol Hepatol 5(10): 11951198.Compton, C.C, 2000. Pathology and Stagging. Cancer.Davies, R.J., et.al, 2005. Colorectal cancer screening : Prospects for molecular stool analysis. Dalam : Haggar, F.A., Boushey, R.P, 2009. Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors. New York, USA: Thieme Medical Publishers, Inc. doi:10.1055/s-0029-1242458.De Jong, A.E., et.al, 2005. Prevalence of adenomas among young individuals at average risk for colorectal cancer.Dalam : Haggar, F.A., Boushey, R.P, 2009. Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors. New York, USA: Thieme Medical Publishers, Inc. doi:10.1055/s-0029-1242458.Ferlay, J., et.al, 2010. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Dalam : Abdullah, M., et.al, 2012. Molecular profile of colorectal cancer in Indonesia: is there another pathway? Jakarta: Gastroenterol Hepatol BedBench 2012;5(2):71-78.Fleming, M., et.al, 2012. Pathologic aspects of colorectal carcinoma. Los Angeles, California, USA: J Gastrointest Oncol 3(3):153-173.Gray, H, 1974. Gray's Anatomy. USA: Running Press Book, 929.Grande, M., et.al, 2008. Evaluation of clinical, laboratory and morphologic prognostic factors in colon cancer. Rome, Italy: World Journal of Surgical Oncology 6:98. doi:10.1186/1477-7819-6-98.Greenberger, J.N., et.al, 2012. Curretnt Diagnosis & Treatment Gastroenterology, Hepatology, & Endoscopy. USA: McGraw Hill, 273-287.Haggar, F.A., Boushey, R.P, 2009. Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors. New York, USA: Thieme Medical Publishers, Inc. doi:10.1055/s-0029-1242458.IARC, 2011. Tumours of The Colon and Rectum. IARC.Ikatan Dokter Indonesia, 2009. Jakarta: IDI. Available from : http://www.idionline.org/?s=KANKER+KOLOREKTAL. [Accessed 24 March 2014]

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