Preventif Pada Preeklampsi

7/30/2019 Preventif Pada Preeklampsi

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Preventif

Dietary manipulationlow-salt diet , calcium supplementation, fish oil

supplementation

Cardiovascular drugsdiuretics, antihypertensive drugs

Antioxidantsascorbic acid (vitamin C), -tocopherol (vitamin E)

Antithrombotic drugslow-dose aspirin, aspirin/dipyridamole, aspirin +

heparin, aspirin + ketanserin

Some Methods to Prevent Preeclampsia That Have Been

Evaluated in Randomized Trials


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Low salt diet : One of the earliest research efforts to

prevent preeclampsia was salt restriction (De Snoo, 1937).

Calcium supplementation : Studies performed in the1980s outside the United States showed that women

with low dietary calcium intake were at significantly

increased risk for gestational hypertension (Belizan and Villar,1980; Lpez-Jaramillo and associates, 1989; Marya and colleagues, 1987).

Fish oil supplementation : supplementation with

these fatty acids would prevent inflammatory-

mediated atherogenesis (Makrides, 2006; Olafsdottir, 2006; Olsen, 2000,and all their colleagues).


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Antihypertensive drugs : They found that women

given diuretics had a decreased incidence of edema

and hypertension, but not of preeclampsia (Churchill andcolleagues, 2007)

Antioxidants : Two naturally occurring antioxidants

vitamins C and Emay decrease such oxidation.

Moreover, women who developed preeclampsiawere found to have reduced plasma levels of these

two vitamins (Raijmakers and associates, 2004)

Antithrombotic agents : There are ample theoretical

reasons that antithrombotic agents might reduce the

incidence of preeclampsia.


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managementTujuan manajemen dasar untuk setiap

kehamilan dengan preeklamsia adalah:

1. Penghentian kehamilan dengan trauma

paling mungkin untuk

ibu dan janin2. Kelahiran bayi yang kemudian tumbuh

subur

3. Lengkap pemulihan kesehatan ibu.


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Diagnosa Dini..!!!

Rawat Jalan atau

Rawat Inap..???


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Kapan.??Evaluasi

.1.Gejala klinis

2.Cek proteinuria

3.Tensi dengan posisi duduk setiap 4 jam4.Tingkat kesejahteraan janin


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Apakah harus MRS..??

In a review of two small randomized trials totaling 106 women at high risk

for preeclampsia, prophylactic bed rest 4 to 6 hours daily at home was

successful in significantly lowering the incidence of preeclampsia but not

gestational hypertension (Meher and Duely, 2006)

These and other observations support the claim that restricted activity

alters the underlying pathophysiology of the preeclampsia syndrome. As

forcomplete bed rest, this is likely unachievable because of the severe

restrictions it places on the otherwise well woman, and it also predisposes

to thromboembolism (Knight and co-workers, 2007)

Pemberian Antihipertensi tidak banyak membaerikan efek signifikan.


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Preventif Pada Preeklampsi

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