National Institute of Health (NIH), USA (1983 – 1984) menentukan indikasi untuk dilakukannya pemeriksaan USG sebagai berikut :

1. Menentukan usia gestasi secara lebih tepat pada kasus yang akan menjalani seksio sesarea berencana, induksi persalinan atau pengakhiran kehamilan secara elektif.2. Evaluasi pertumbuhan janin, pada pasien yang telah diketahui menderita insufisiensi uteroplasenter, misalnya preeklampsia berat, hipertensi kronik, penyakit ginjal kronik, atau diabetes mellitus berat; atau menderita gangguan nutrisi sehingga dicurigai terjadi pertumbuhan janin terhambat, atau makrosomia.3. Perdarahan per vaginam pada kehamilan yang penyebabnya belum diketahui.4. Menentukan bagian terendah janin bila pada saat persalinan bagian terendahnya sulit ditentukan atau letak janin masih berubah-ubah pada trimester ketiga akhir.5. Kecurigaan adanya kehamilan ganda berdasarkan ditemukannya dua DJJ yang berbeda frekuensinya atau tinggi fundus uteri tidak sesuai dengan usia gestasi, dan atau ada riwayat pemakaian obat-obat pemicu ovulasi.6. Membantu tindakan amniosentesis atau biopsi villi koriales.7. Perbedaan bermakna antara besar uterus dengan usia gestasi berdasarkan tanggal hari pertama haid terakhir.8. Teraba masa pada daerah pelvik.9. Kecurigaan adanya mola hidatidosa.10. Evaluasi tindakan pengikatan serviks uteri (cervical cerclage).11. Suspek kehamilan ektopik.12. Pengamatan lanjut letak plasenta pada kasus plasenta praevia.13. Alat bantu dalam tindakan khusus, misalnya fetoskopi, transfusi intra uterin, tindakan “shunting”, fertilisasi in vivo, transfer embrio, dan “chorionic villi sampling” (CVS).14. Kecurigaan adanya kematian mudigah / janin.15. Kecurigaan adanya abnormalitas uterus.16. Lokalisasi alat kontrasepsi dalam rahim (AKDR).17. Pemantauan perkembangan folikel.18. Penilaian profil biofisik janin pada kehamilan diatas 28 minggu.19. Observasi pada tindakan intra partum, misalnya versi atau ekstraksi pada janin kedua gemelli, plasenta manual, dll.20. Kecurigaan adanya hidramnion atau oligohidramnion.21. Kecurigaan terjadinya solusio plasentae.22. Alat bantu dalam tindakan versi luar pada presentasi bokong.23. Menentukan taksiran berat janin dan atau presentasi janin pada kasus ketuban pecah preterm dan atau persalinan preterm.24. Kadar serum alfa feto protein abnormal.25. Pengamatan lanjut pada kasus yang dicurigai menderita cacat bawaan.26. Riwayat cacat bawaan pada kehamilan sebelumnya.27. Pengamatan serial pertumbuhan janin pada kehamilan ganda.28. Pemeriksaan janin pada wanita usia lanjut (di atas 35 tahun) yang hamil.

Tujuan Kuretase a.Kuret sebagai diagnostik suatu penyakit rahimYaitu mengambil sedikit jaringan lapis lendir rahim, sehingga dapatdiketahui penyebab dari perdarahan abnormal yang terjadi misalnya perdarahan pervaginam yang tidak teratur, perdarahan hebat, kecurigaanakan kanker endometriosis atau kanker rahim, pemeriksaan kesuburan/infertilitas. 

b.Kuret sebagai terapiYaitu bertujuan menghentikan perdarahan yang terjadi padakeguguran kehamilan dengan cara mengeluarkan hasil kehamilan yangtelah gagal berkembang, menghentikan perdarahan akibat mioma dan polip dengan cara mengambil mioma dan polip dari dalam rongga rahim,menghentikan perdarahan akibat gangguan hormon dengan caramengeluarkan lapisan dalam rahim misalnya kasus keguguran,tertinggalnya sisa jaringan plasenta, atau sisa jaringan janin di dalamrahim setelah proses persalinan, hamil anggur, menghilangkan polip rahim

Indications for a diagnostic dilation and curettage include the following:

Abnormal uterine bleeding : irregular bleeding, menorrhagia, suspected malignant or premalignant condition

Retained material in the endometrial cavity Evaluation of intracavitary findings from imaging procedures (abnormal endometrial appearance

due to suspected polyps or fibroids) Evaluation and removal of retained fluid from the endometrial cavity (hematometra, pyometra) in

conjunction with evaluating the endometrial cavity and relieving cervical stenosis Office endometrial biopsy insufficient for diagnosis or failed due to cervical stenosis Endometrial sampling in conjunction with other procedures (eg, hysteroscopy,laparoscopy)

The evaluation of the uterine cavity by dilation and curettage may be helpful when an office technique, such as ultrasound, is unable to fully elucidate the endometrium due to shadowing from leiomyomata, a pelvic mass, or loops of bowel.

Several studies have evaluated the effectiveness of obtaining endometrial tissue by endometrial sampling versus D&C. One study compared aspiration biopsy (Pipelle) with D&C. The D&C procedure was performed without hysteroscopy. This sample of 673 women underwent hysterectomy following the endometrial sampling or curettage. The concordance of results was 67% between endometrial biopsy and hysterectomy versus 70% between D&C without hysteroscopy and hysterectomy. The negative predictive value was 98% for detection of malignancy. In their conclusions, the authors recommended a presampling evaluation of the endometrium by a technique such as transvaginal ultrasound.[2]

Another study of 366 women evaluated histopathologic findings obtained by hysteroscopically directed biopsies, versus pathology results of tissue obtained at D&C. Concordance of results for the 2 procedures was 88.8%. In their conclusions, the authors stated that although hysteroscopy with directed biopsy was adequate for obtaining diagnosis from focal lesions, it may not be sufficient for diagnosis of all pathologic findings in the endometrium, including hyperplasia. They recommended global endometrial sampling, such as by D&C, be included for more thorough diagnosis.[3]

Dilation and curettage may also be a therapeutic procedure. Examples of this use include the following:

Removal of retained products of conception (eg, incomplete abortion, missed abortion, septic abortion, induced pregnancy termination)

Suction procedures for management of uterine hemorrhage Treatment and evaluation of gestational trophoblastic disease Hemorrhage unresponsive to hormone therapy[1]

In conjunction with endometrial ablation for histologic evaluation of the endometrium

Contraindications

There are few contraindications to gentle office dilation and curettage, but a more vigorous examination may require an operative suite with regional or general anesthesia. Paracervical block or intravenous sedation with an anesthesia team standing by for assistance may also be an option. Intolerance to office examinations or procedures may determine the setting for the procedure.

Absolute contraindications to dilation and curettage include the following:

Viable desired intrauterine pregnancy Inability to visualize the cervical os Obstructed vagina

Relative contraindications to dilation and curettage include the following:

Severe cervical stenosis Cervical/uterine anomalies Prior endometrial ablation Bleeding disorder Acute pelvic infection (except to remove infected endometrial contents) Obstructing cervical lesion

These contraindications may be surmounted in some cases. For example, magnetic resonance imaging may define the anatomy of the cervical or uterine anomaly, allowing safe exploration of the endocervix and endometrium.

Complications

Complications can occur at the time of diagnostic dilation and curettage. Careful performance of the procedure should minimize these events. Possible complications include the following:

Bleeding or hemorrhage Cervical laceration Uterine perforation Postprocedural infection Postprocedural intrauterine synechiae (adhesions) Anesthetic complications

Complications, particularly uterine perforation, may be increased in a patient with a recent pregnancy or gestational trophoblastic disease, prior endometrial ablation, distorted anatomy, cervical stenosis, or current uterine infection.

Cervical Injury

Laceration of the cervix primarily occurs during traction, with a counterforce applied during dilation. It seems to occur most frequently with use of a single-tooth tenaculum, especially when it is placed vertically on the lip of the cervix. A Bierer multi-toothed tenaculum penetrates less deeply into the cervical tissue and transfers force over a greater area, potentially decreasing the risk of laceration.

Lacerations are generally managed with an interrupted or running interlocking dissolvable suture. The same technique would be applied for a laceration of the posterior cervical lip.

Placement of a tenaculum is not recommended at the lateral aspect of the cervix because of the location of the cervical branches of the uterine artery.

The risk of laceration is reduced by reducing force at dilation, using more tapered Pratt dilators or osmotic preparation before the procedure with laminaria or prostaglandin.

Uterine Perforation

Uterine perforation is one of the more common complications of dilation and curettage. Risks are increased when dealing with a pregnant or recently postpartum uterus (5.1%) and are less frequent at the time of a dilation and curettage remote from pregnancy (0.3% for premenopausal women and 2.6% for postmenopausal women).[4, 5, 6]

The instruments most commonly associated with uterine perforation are the uterine sound or dilators. If perforation is known to have occurred with a blunt instrument, observation of vital and peritoneal signs for several hours is all that is needed. If suspicion that a sharp instrument, such as a curette, has perforated

the uterus or if the fat has been retrieved by curettage, then intraabdominal injury must be excluded by laparoscopy. Active bleeding may necessitate a laparotomy.

Infection

Infection related to diagnostic dilation and curettage is rare and is most likely whencervicitis is present at the time of the procedure. One study of infections related to dilation and curettage documented a 5% incidence of bacteremia following dilation and curettage with a very rare incidence of septicemia.

Prophylactic antibiotics are not recommended for any dilation and curettage, including for those women who generally require subacute bacterial endocarditis prophylaxis.

Intrauterine Adhesions

Curettage after delivery or abortion may result in endometrial injury and subsequent development of intrauterine adhesions, termed Asherman syndrome. The development of uterine synechiae may also be associated with prior endometrial ablation procedures. Intrauterine adhesions may make future diagnostic curettage more difficult and increase the risk of uterine perforation. Previous procedures such as endometrial ablation may also increase the risk of cervical stenosis.

Trophoblastic Embolization

Embolization of trophoblastic tissue in the systemic circulation is a very rare complication of dilation and curettage for removal of gestational trophoblastic disease. This event has been associated with thyroid storm, cardiovascular collapse, and death. A diagnostic dilation and curettage in patients for whom gestational trophoblastic neoplasia is suspected should be performed in an operating room with anesthesia.