Compounding&Dispensing

8/12/2019 Compounding&Dispensing

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COMPOUNDING &

DISPENSINGHenny Lucida, PhD, Apt


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Pretest

Jawablah soal berikut ini pada kertas yangdisediakan:

1. Hitunglah jumlah kalium permanganat yang

diperlukan untuk membuat larutan PK denganrasio 1:25 sebanyak 300 mL. Larutan berapa %kah itu?

2. Berapakah mg aluminium asetat dibutuhkanuntuk membuat larutan 0,03 g b/v sebanyak500 mL


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Pretest (contd)

3. Nyatakan dalam %, bila 900 mg NaCl

dilarutkan dalam 100 mL aqua pi

4. Berapa mg/L kah 0,7 ppm b/v batas fluorida

dalam air minum

5. Sebanyak 25 g salep mengandung 5 g calamin.

Berapa jumlah calamin dalam 60 g salep?


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Pretest (contd)

6. Dosis fenitoin yang direkomendasikan untukpasien A adalah 840 mg. Injeksi fenitoinmengandung 50 mg/mL zat aktif. Berapa

volume injeksi yang diperlukan untukmemenuhi dosis tersebut?

7. Setiap 5 mL suspensi mengandungparasetamol 120 mg. Berapa volume suspensiyang mengandung 300 mg parasetamol?


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Pretest (contd)

8. Sebanyak 5 g sediaan mengandung 250 mg

sulfur di dalam paraffin kuning. Nyatakan

kadar obat dalam rasio ( x bagian dalam y

bagian b/b)

9. Suatu obat cair dicampurkan dengan pelarut

lain sehingga kadarnya 5% v/v. Tentukan rasio

nya terhadap pelarut dan nyatakan kadar dalammL/mL.


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Pretest (contd)

10. Berapa mg senyawa x terdapat dalam 100

mL larutan 0,01%?


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History

Pharmacy is the art or practice of preparing and

preserving drugs, and of compounding and

dispensing medicines according to the prescriptions

of physicians Pharmacy is (1) the art, practice, or profession of

preparing, preserving, compounding and dispensing

medical drugs and (2) a place where medicines are

compounded or dispensed


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History (contd)

Pharmacy is the science, art, and practice of

preparing, preserving, compounding, and

dispensing medicinal drugs and of giving

instructions for their use


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Definition

Compounding: meracik

Pharmaceutical CompoundingCompounded Formulations

Dispensing: menyerahkan

Dispensing of medication


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Compounding today

Is rapidly growing component of pharmacy practice,due to:

Individualized patient therapy

Lack of commercially available products Home health care

Intravenous admixture programs

Total parenteral nutrition programs

Problem solving for the physician and patient toenhance compliance with a specific therapeuticregimen


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Trends kematian di AS akibat peresepan vs kecelakaan berbagaialat transportasi,19791998 (1979 D 1).

Increase in US medication error deaths, Lancet, February 28, 1998


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Annual Accidental Deaths (IOM

1999)

0

20000

40000

60000

80000

100000

Medical Auto Workplace Air


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Pharmacist

A unique professionals

A single mistake in the daily practice of their

profession may result in potential tragedy

Possess knowledge and skills that are not

duplicated by any other profession


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Compounding

Means the preparation, mixing, assembling,

packaging, or labeling of a drug or device

(1) As the result of a practitioners Prescription

(2) For the purpose of doing research, teaching

or chemical analysis

Compounding&Dispensing

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