Mikronesia, Negara Federasi diberikan multidrugPerawatan Preventif untuk 12 bulan dalam secara langsungProgram terapi.78pasien tidak diberikan pencegahanPengobatanpenyakit tuberkulosis dikembangkan. Walaupun tidak adaKesimpulan nitive defi dapat ditarik dari studi ini,Findingsmenyarankan bahwa perawatan preventif MDRTuberkulosiskontak adalahtiruan menyerupai manusia benefi anakInternational guidelines for the management of MDRtuberculosis contacts vary. The UK National Institute forHealth and Clinical Excellence and WHO advocate thatafter screening for tuberculosis disease all contacts ofpatients with infectious MDR tuberculosis should befollowed up without medication, because the datasupporting the use of drugs other than isoniazid andrifampicin are limited.64,79 The WHO guideline doesimply that contacts of MDR tuberculosis source casesmight also have been exposed to drug-susceptible sourcecases and, therefore, could be infected with a strainsusceptible to isoniazid.61 The National Department ofHealth of South Africa suggests giving high-doseisoniazid (15 mg/kg) to asymptomatic children aged5 years and younger who are contacts of MDRtuberculosis source cases