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1. Hipertensi

a. Algoritma Hipertensi

 b. Penggolongan Obat Hipertensi

Klass Subklass Obat (nama dagang) dosis Pemakaian

 perhari

Diuretik 

Thiazid

hlortalidone (H!grotone) 1"#$ % "$ 1

H!dro&hlorotalidone ('i&rozide) 1"#$ % "$ 1

ndapamide (azol) 1#"$ * "#$ 1

'etolazone (+aro,ol!n) "#$ * $ 1

oop Diuretik -umetanide (-ume,) #$ * / "0urosemide (asi,) " * "

Torsemide (Demade,) $ % 1 1

Potassium

Sparing

Amiloride ('idamor) $ * 1 1 or "

Amirolide 2 HT ('odureti&) $ * 1 1

Triamterene (D!erenum) $ * 1 1 or "

Triamterene 2 HT (D!azide) 34#$ % 4$ 1

AldosteronAntagonis

5plerenone (nspra) $ * 1 1 or "

Spirinola&tone (Alda&ton) "$ * $ 1 or "

Spirinola&tone 2 HT (Alda&tazide) "$ % $ 1

Angiotensin

on6erting

5nzime

nhibitor (A5 in)

-enazepril (otensin) 1 * / 1 or "

aptopril (aptopen) 1"#$ * 1$ " or 3

5nalapril (7asote&) $ * / 1 or "

0osinopril ('onopril) 1 * / 1

isinopril (Prini6il 2 +estril) 1 * / 1

'oe,ipril (8ni6as&) 4#$ * 3 1 or "

Perindopril (A&eon) / * 19 1

:uinapril (A&&upril) 1 * 1 or "

;amipril (Alta&e) "#$ %" 1or "

Trandolapril ('a6ik) 1 * / 1

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Angiotensin ;e&eprot

-loker (A;-)

andesartan (Ata&and) * 3" 1 or "

5posartan (Te6eten) 9 * 1 or "

bersartan (A6apro) 1$ * 3 1

osartan (ozaar) $ * 1 1 or "

Olmesartan (-eni&ar) " * / 1

Telmisartan ('i&ardis) " * 1

7alsartan (Dio6an) * 3" 1

al&ium

anal

-lo&ker (-)

Dih!dropiridi

n

Amlodipin (<or6as&) "#$ * 1 1

0elodipine (Plendii) $ * " 1

sradipine (D!na&ir&) $ * 1 "

sradipine S; (D!na&ir& S;) $ * " 1

 <i&ardipin S; (ardene S;) 9 * 1" "

 <i=edipin ong%A&ting (Adalat ) 3 * > 1

 <isoldipin (Sular) 1 % / 1

 <on%D!hidropiridi

n

Diltiazem S; (ardizem S;) 1 * 39 "

Ditiazem 5,tended%release (ardizem A) 1" * / 1

7erapamil S; (alan S; 2 soptin S;) 1" * $/ 1

7erapamil O5; (o6era HS) 1 * /" 1

7erapamil Oral Absorption (7arelan P') 1 % / 1

-eta -lo&ker 

ardio

sele&ti6e

Atenolol (Tenormin) "$ * 1 1

-eta,olol (karlone) $ * " 1

-isoprolol (+ebeta) ".$ * 1 1

'etopolol tartrate (opressor) 1 * / "

'etoprolol Su&&inate 5; (Toprol ?) 1 % $ 1

 <on%Sele&ti6e

 <adolol (ogard) / * 1" 1

Propanolol (nderal) 19 * / "

Propanolol ong%a&ting (nderal A) * 3" 1

Timolol (-lo&adren) 1 % / 1

Akti6itas

ntrinsik S!mtomimetik 

A&ebutolol (Se&tral) " * "

arteolol (artrol) ".$ * 1 1

Penbutolol (e6atol) 1 * / 1

Pindolol (7isken) 1 * 9 "

ampuran

Al=a dan -eta

-lo&ker 

ar6edilol (oreg) 1".$ * $ "

ar6edilol 0os=at (oreg ;) " * 1

abetelol (<ormod!ne) " * "

 

". H!perlipidemia

a. 'ekanisme aksi obat

Klass Mechanism of Action Effect on LipidEffect on

LipoproteinResin @ D &atabolism

absorpsi Kolesterol

kolesterol Dl

@ 7D

Niacin D 7D sintess

Trigliseride Kolesterol

D 7D

@ HD

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Fibrate @ 7D learean&e

7D sintesis

Trigliseride

Kolesterol

D

7D

@ HD

Inhibitor HMG-

CoA

@ D &atabolism

D sintesis

Kolesterol D

Ezetimibe

 b. Penggolongan Obat

Golonan !bat "nama pasaran#

$osis

pen%naan

perhari

$osis

ma&sim%m

perhari

0ibrate0eno=ibrate (Tri&or) $/ mg 2 93 mg "1 mg

Bemi=ibrozil (opid) 9 mg (",1) 1#$ gr  

nhibitor H'B%oA

o6astatin ('e6a&or) " * / mg mg

Pra6astatin (Pra6a&hol) 1 * " mg / mg

Sim6astatin (+o&or) 1 * " mg mgAtro6astain (ipitor) 1 mg mg

;osu6astatin (restor) $ mg / mg

;esin

holest!ramin (:uestran) gr (3,1) 3" gr  

olestipol H!dro&loride (olestid) 1 gr (",1) 3 gr  

olese6elam (Cel&hol) 1#4$ mg (",1) /#34$ mg

 <ia&in <ia&in " gr (",1) > gr 

3. Diabetes 'elitus

a. a=d

/. Diare

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$. 'ual 'untah

9. Depresi

4. Kosntipasi

. Asma

>. Pirai 2 Asam 8rat