INFEKSI BAKTERI ANAEROB

7/25/2019 INFEKSI BAKTERI ANAEROB

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INFEKSI BAKTERI ANAEROB

OLEHOLEHNURROKHMANNURROKHMAN

BAGIAN MIKROBIOLOGIBAGIAN MIKROBIOLOGI

FAKULTAS KEDOKTERAN UGMFAKULTAS KEDOKTERAN UGM


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INFEKSI BAKTERI-BAKTERI ANAEROB

BAKTERI ANAEROBBAKTERI YG DALAM PERTUMBUHANNYA

MEMBUTUHKAN PENURUNAN OKSIGENDLM JUMLAH

TERTENTU DAN SENSITIF METRONIDAZOL

MACAMNYA:

ANAEROB OBLIGAT

ANAEROB FAKULTATIFMIKROAEROFILIK


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BERDASARKAN BENTUK DAN SIFAT

PENGECATAN GRAM

BATANG GRAM POSITIFBATANG GRAM NEGATIF

KOKUS GRAM POSITIF

KOKUS GRAM NEGATIF

BATANG GRAM POSITIF

ActinomycesLactobacillus

PropionibacteriumEubacteriumBifdobacteriumArachnia

Clostridium

BATANG GRAM NEGATIF

Bacteroides

Prefotella

PorphyromonasFusobacteria


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KOKUS GRAM POSITIF

Peptostreptococcus

KOKUS GRAM NEGATIFVeillonella

BERDASARKAN KEMAMPUAN MEMBENTUK SPORA

anaerob bersora

Clostridium

anaerob !"# bersoraBacteroides

Prefotella

Porphyromonas


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DIAGNOSIS INFEKSI BAKTERI ANAEROB

Sekret yg berba b!k

In"ek!i ter#a$i $ekat %er&kaan &ko!a

A$anya ga! $ala& #aringan

biakan aerob negati" 'ti$ak t&b()


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CLOSTRIDIUM

MERUPAKAN BAKTERI

ben!$# ba!an%

besar

%ra& os'!'(

&o!')

MORFOLOGI KOLONI

#o)on' besar

*C. perfringens+

#o)on' #e,')*C. tetani+

,e&b$n%

!e' $!$-

b$)a!

-e&o)'s's *.+


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Pen/a#'! /% "'sebab#an o)e- C)os!r'"'$&

"'be"a#an &en0a"' 1:

23 )$#a "an 'n(e#s' 0ar'n%an *&'one#ros's4 !e!an$s4 "an #o)'!'s+

13 'n!o#s'#as' &a#anan

SIFAT PERTUMBUHAN

!"# "aa! -'"$ aerob

!"# $n/a s'!o#ro&!"# $n/a s'!o#ro& o#s'"ase

!a# "! &e&e,a- H1O1

!a# $n/a #a!a)ase

!a# $n/a ero#s'"ase

!a# $n/a s$ero#s'"a "'s&$!ase


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C. perfringensC. perfringens

soil, fecal contaminationsoil, fecal contamination

warwar

gas gangrenegas gangrene

swelling of tissuesswelling of tissues gas releasegas release

* fermentation productsfermentation products

wound contaminationwound contamination


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Without treatment deathWithout treatment death

occurs within 2 daysoccurs within 2 days

effective antibiotic therapyeffective antibiotic therapy

debridementdebridementanti-toxinanti-toxin

amputation death is rareamputation death is rare


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!aboratory identification

lecithinase productionlecithinase production


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C. botulinumC. botulinum

food poisoningfood poisoning rarerare

fatalfatal

gerination of sporegerination of spore

inade!"atel# sterili$ed %anned foodinade!"atel# sterili$ed %anned food

&oe&oe

not an infe%tionnot an infe%tion


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Bot"lin" to'inBot"lin" to'in

(inds perip&eral ner)e re%eptors(inds perip&eral ner)e re%eptors

a%et#l%&oline ne"rotransittera%et#l%&oline ne"rotransitter

in&i(its ner)e ip"lsesin&i(its ner)e ip"lses

fla%%id paral#sisfla%%id paral#sis

deat&deat&

respirator#respirator# %ardia% fail"re%ardia% fail"re


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C. difficileC. difficile

"fter antibiotic use"fter antibiotic use

intestinal normal floraintestinal normal flora

greatly decreasedgreatly decreased colonization occurscolonization occurs enterotoxin secretedenterotoxin secreted

pseudomembanous colitispseudomembanous colitis


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Clostridi" tetaniClostridi" tetani


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TetanospasinTetanospasin

Men#e(ar se%ara sistei*Men#e(ar se%ara sistei*

ne"roto*sin potensialne"roto*sin potensial

Mengi*at reseptor gangliosidMengi*at reseptor gangliosid

eng&a(at ne"ron di CNSeng&a(at ne"ron di CNS

Otot (e*er+a ter"s ener"sOtot (e*er+a ter"s ener"sspasti% ,rigid paral#sisspasti% ,rigid paral#sis

.a*t" in*"(asi /-01 &ari.a*t" in*"(asi /-01 &ari


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Treatent and 2re)ention

Te!an$s I&&$ne G)ob$)'n *TIG+Te!an$s an!'!o5'n *TAT+ (ro& -orses

en','))'n or !e!ra,/,)'ne

&$s,)e re)a5an!sTra,-eos!o&/

6a,,'na!e"


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INFEKSI BAKTERI ANAEROB

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