How to Formulate a Researchable

Question based on PICOSAn Academic presentation by

Dr. Nancy Agnes, Head, Technical Operations, Pubrica Group: www.pubrica.comEmail: sales@pubrica.com

In Brief

Introduction

Formulating the research question

Importance of PICO question

The PICO Formula

Conclusion

Today's Discussion Outline

IN BRIEFOne of the most difficult challenges a researcher faces before starting a project is generating a researchable question.

practice andUnanswered questions in current

interactions

dictating

clinical alternatetreatments will lead to the formulation of a

clinical research question.

Contd...

It would help researchers by giving them step-by-step instructions about howto formulate a research question.

It also explains how to frame a research question using PICO(population, intervention, control, and outcomes) parameters.

Finally, before starting a research question, we evaluate the characteristics ofa research project.

INTRODUCTIONA researchable question can be challenged, investigated, and analysed to provide valuable knowledge about an issue.

A successful research experiment is determined by how well an author formulates the research issue in light of everyday research and clinical practice issues.

Contd...

The research project’s fundamental issues provide crucial details for determining whether the subject is appropriate, researchable, and meaningful.

A well-formulated research question necessitates excessive detail and precision, which guides the project’s execution while identifying variables and the population of interest.

We’ll go through a clinical situation and see how clinical problems emerge and how they will help us with the facts we need to address our question.

FORMULATING THERESEARCH QUESTION CASE

A 2-year-old boy with a fever and severe pain in his right ear visits an emergency doctor.

His mother is concerned that he has been on the antibiotic amoxicillin for the last two weeks, and he has a history of chronic ear infections.

Contd...

She is worried about the long-term effects of antibiotic use.

She’s still worried about the consequences of chronic ear infections.

Because of its side effects, such as constant diarrhoea, she needs to know whether anamoxicillin prescription is safe or whether another antibiotic can replace it.

This case raises several questions, which can be divided into two categories: history and foreground.

Contd...

“Background Queries” are generic questions about a health condition or illness.

These problems usually include comparing two objects, such as twomedications or treatments, or two diagnostic processes, etc.

PICO (population, intervention, control, and outcomes) is a commonly used method for framing a “foreground” study issue [Table 1].

Contd...

POPULATION OR PROBLEM

Addressing a specific population, its important characteristics and demographic information.

You may classify the paediatric population with otitis media, the age group, sex, presenting complaint, and experience from the above example from the above case.

INTERVENTION OR TREATMENT OF INTEREST

Treatments, procedures, laboratory tests, and risk or prognostic variablesare also examples of interventions.

Contd...

The intervention in this situation could be your treatment strategy for the patient, including new medication, a screening test, a prognostic factor, or a procedure.

when a new treatment is linked to one that still exists

E.g., based on your observations in a clinic, cefuroxime is a safertherapeutic choice for otitis media than amoxicillin.

Still, you are unsure about its effectiveness in paediatric otitis media patients.

COMPARATOR OR CONTROL

Contd...

OUTCOME

The intervention’s result is known as the outcome—for example, its ability to manage discomfort.

As a result, in the example above, the effect may be pain relief, infection resolution, or a reduction in the risk of developing resistance.

A successful primary outcome should be simple to quantify, specific,valid, reproducible, and appropriate to your research issue.

In a traditional clinical environment, a clinician must be aware of contextand foreground questions based on their knowledge of a specific condition and treatment.

Contd...

More background questions are presented after history questions are asked.

Medical considerations emerge from a clinical work’s central problems.

For instance, determining the causes or risk factors (etiological questions), evaluating diagnostic measures based on sensitivity and specificity (diagnostic question), determining the best treatment choices (therapeutic question), and the treatment outcome (prognostic question).

IMPORTANCE OF PICOQUESTION

The PICO question is a different way of thinking about clinical issues that emerge in health care.

These questions, unlike informational questions, are very complex and can be difficult to formulate.

They are made up of particular elements or principles that have a specific role in the evidence- based process.

Contd...

THE PICO FORMULA

The fact that this procedure is known as

formulating is no coincidence. When you ask a PICO question, you’re building a formula that accomplishes many goals

Contd...

Define the elements or ideas in the query to help focus it.

Used to determine which publications in a search retrieval better answer the query

Defines the principles that would be used when runninga complex literature search

Assists in determining whether the studies found to answerthe initial question’s components.

At the end of the review, you’ll have all the details you need to decide if the PICO action can be applied.Contd...

A concentrated research question contributes to structured research project preparation.

It is not a shortage of concepts that is causing the difficulties in framing a study issue.

The task is to transform a novel research issue into a proper study plan, which is the next step in the research question refinement process

CONCLUSIONA well-formulated research topic is a good place to proceed when doing a good study or practising evidence-based medicine.

A clinician should use the process outlined in this paper to formulate a question and look for a response, and a researcher can use it to create a new research project.

Contd...

The traditional method is first to classify a research question, then do a detailed literature review using the PICO criteria.

If the research question is well-defined, it will lead to a good study design and methodology. Finally, the findings are applied to a particular patient group.

In short, a researchable topic points to truth rather than opinions and is related to the ultimate purpose of t he research project

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